Primary Site >> Colorectal Cancer

Gene >> BUB1

Journal: Nature. 1998 Mar 19;392(6673):300-3.
Title: Mutations of mitotic checkpoint genes in human cancers.
Author: Cahill, D P|Lengauer, C|Yu, J|Riggins, G J|Willson, J K|Markowitz, S D|Kinzler, K W|Vogelstein, B
PMID: 9521327
Journal: Jpn J Cancer Res. 1999 Aug;90(8):837-40.
Title: Mutational inactivation of mitotic checkpoint genes, hsMAD2 and hBUB1, is rare in sporadic digestive tract cancers.
Author: Imai, Y|Shiratori, Y|Kato, N|Inoue, T|Omata, M
PMID: 10543255
Journal: Cancer Lett. 2000 May 1;152(2):193-9.
Title: Mutation and expression analysis of human BUB1 and BUB1B in aneuploid breast cancer cell lines.
Author: Myrie, K A|Percy, M J|Azim, J N|Neeley, C K|Petty, E M
PMID: 10773412
Journal: Jpn J Cancer Res. 2000 May;91(5):504-9.
Title: Infrequent mutation of the hBUB1 and hBUBR1 genes in human lung cancer.
Author: Sato, M|Sekido, Y|Horio, Y|Takahashi, M|Saito, H|Minna, J D|Shimokata, K|Hasegawa, Y
PMID: 10835495
Journal: Cancer Res. 2000 Aug 15;60(16):4349-52.
Title: Genomic instability at the BUB1 locus in colorectal cancer, but not in non-small cell lung cancer.
Author: Jaffrey, R G|Pritchard, S C|Clark, C|Murray, G I|Cassidy, J|Kerr, K M|Nicolson, M C|McLeod, H L
PMID: 10969775
Journal: Oncol Rep. 2001 Jan-Feb;8(1):39-42.
Title: Mutation analysis of hBUB1, human mitotic checkpoint gene in multiple carcinomas.
Author: Mimori, K|Inoue, H|Alder, H|Ueo, H|Tanaka, Y|Mori, M
PMID: 11115566
Journal: Nat Cell Biol. 2001 Apr;3(4):429-32.
Title: A role for the Adenomatous Polyposis Coli protein in chromosome segregation.
Author: Kaplan, K B|Burds, A A|Swedlow, J R|Bekir, S S|Sorger, P K|Nathke, I S
PMID: 11283619
Journal: Oncol Rep. 2001 Jul-Aug;8(4):791-4.
Title: No mutations of the Bub1 gene in human gastric carcinomas.
Author: Shigeishi, H|Yokozaki, H|Kuniyasu, H|Nakagawa, H|Ishikawa, T|Tahara, E|Yasui, W
PMID: 11410785
Journal: Cancer Res. 2002 Jan 1;62(1):13-7.
Title: Genetic and epigenetic inactivation of mitotic checkpoint genes hBUB1 and hBUBR1 and their relationship to survival.
Author: Shichiri, Masayoshi|Yoshinaga, Keigo|Hisatomi, Hisashi|Sugihara, Kenichi|Hirata, Yukio
PMID: 11782350
Journal: Cancer Metastasis Rev. 2004 Jan-Jun;23(1-2):11-27.
Title: Genomic instability and colon cancer.
Author: Grady, William M
PMID: 15000146
Journal: Cytogenet Genome Res. 2004;104(1-4):333-40.
Title: Possible causes of chromosome instability: comparison of chromosomal abnormalities in cancer cell lines with mutations in BRCA1, BRCA2, CHK2 and BUB1.
Author: Grigorova, M|Staines, J M|Ozdag, H|Caldas, C|Edwards, P A W
PMID: 15162061
Journal: J Cell Biol. 2007 Jan 15;176(2):183-95.
Title: Loss of APC induces polyploidy as a result of a combination of defects in mitosis and apoptosis.
Author: Dikovskaya, Dina|Schiffmann, David|Newton, Ian P|Oakley, Abigail|Kroboth, Karin|Sansom, Owen|Jamieson, Thomas J|Meniel, Valerie|Clarke, Alan|Nathke, Inke S
PMID: 17227893
Journal: PLoS One. 2007 Dec 26;2(12):e1337.
Title: Inhibition of Chk1 kills tetraploid tumor cells through a p53-dependent pathway.
Author: Vitale, Ilio|Galluzzi, Lorenzo|Vivet, Sonia|Nanty, Lisa|Dessen, Philippe|Senovilla, Laura|Olaussen, Ken A|Lazar, Vladimir|Prudhomme, Michelle|Golsteyn, Roy M|Castedo, Maria|Kroemer, Guido
PMID: 18159231
Journal: PLoS One. 2009;4(2):e4388.
Title: Five quantitative trait loci control radiation-induced adenoma multiplicity in Mom1R Apc Min/+ mice.
Author: Elahi, Eiram|Suraweera, Nirosha|Volikos, Emmanouil|Haines, Jackie|Brown, Natalie|Davidson, Gerovie|Churchman, Mike|Ilyas, Mohammed|Tomlinson, Ian|Silver, Andrew
PMID: 19194513
Journal: Cell Cycle. 2010 May;9(9):1711-6.
Title: Chromosome missegregation causes colon cancer by APC loss of heterozygosity.
Author: Baker, Darren J|van Deursen, Jan M
PMID: 20404532
Journal: Oncogene. 2010 Dec 9;29(49):6418-27.
Title: Defining the role of APC in the mitotic spindle checkpoint in vivo: APC-deficient cells are resistant to Taxol.
Author: Radulescu, S|Ridgway, R A|Appleton, P|Kroboth, K|Patel, S|Woodgett, J|Taylor, S|Nathke, I S|Sansom, O J
PMID: 20729907
Journal: Oncol Rep. 2010 Oct;24(4):1029-34.
Title: Possibility of paclitaxel as an alternative radiosensitizer to 5-fluorouracil for colon cancer.
Author: Hiro, Junichiro|Inoue, Yasuhiro|Toiyama, Yuji|Yoshiyama, Shigeyuki|Tanaka, Koji|Mohri, Yasuhiko|Miki, Chikao|Kusunoki, Masato
PMID: 20811685
Journal: BMJ Case Rep. 2013 Feb 25;2013. pii: bcr2013008684.
Title: Absence of aneuploidy and gastrointestinal tumours in a man with a chromosomal 2q13 deletion and BUB1 monoallelic deficiency.
Author: Hoang, Don|Sue, Gloria R|Xu, Fang|Li, Peining|Narayan, Deepak
PMID: 23440991
Journal: Gastroenterology. 2013 Sep;145(3):544-7.
Title: Germline mutations in the spindle assembly checkpoint genes BUB1 and BUB3 are risk factors for colorectal cancer.
Author: de Voer, Richarda M|Geurts van Kessel, Ad|Weren, Robbert D A|Ligtenberg, Marjolijn J L|Smeets, Dominique|Fu, Lei|Vreede, Lilian|Kamping, Eveline J|Verwiel, Eugene T P|Hahn, Marc-Manuel|Ariaans, Maayke|Spruijt, Liesbeth|van Essen, Ton|Houge, Gunnar|Schacke
PMID: 23747338
Journal: Oncotarget. 2015 Jul 10;6(19):17342-53.
Title: Deregulation of HMGA1 expression induces chromosome instability through regulation of spindle assembly checkpoint genes.
Author: Pierantoni, Giovanna Maria|Conte, Andrea|Rinaldo, Cinzia|Tornincasa, Mara|Gerlini, Raffaele|Federico, Antonella|Valente, Davide|Medico, Enzo|Fusco, Alfredo
PMID: 26009897
Journal: Cell Cycle. 2016;15(6):812-8.
Title: Hmga1 null mouse embryonic fibroblasts display downregulation of spindle assembly checkpoint gene expression associated to nuclear and karyotypic abnormalities.
Author: Pierantoni, Giovanna Maria|Conte, Andrea|Rinaldo, Cinzia|Tornincasa, Mara|Gerlini, Raffaele|Valente, Davide|Izzo, Antonella|Fusco, Alfredo
PMID: 26889953
Journal: Genes Chromosomes Cancer. 2016 Nov;55(11):855-63.
Title: Prevalence of germline mutations in the spindle assembly checkpoint gene BUB1B in individuals with early-onset colorectal cancer.
Author: Hahn, Marc-Manuel|Vreede, Lilian|Bemelmans, Sonja A S A|van der Looij, Erica|van Kessel, Ad Geurts|Schackert, Hans K|Ligtenberg, Marjolijn J L|Hoogerbrugge, Nicoline|Kuiper, Roland P|de Voer, Richarda M
PMID: 27239782
Journal: Oncol Lett. 2016 Dec;12(6):5092-5098.
Title: Identification of potential therapeutic targets for colorectal cancer by bioinformatics analysis.
Author: Yan, Ming|Song, Maomin|Bai, Rixing|Cheng, Shi|Yan, Wenmao
PMID: 28105216
Journal: Gastroenterology. 2017 Jan;152(1):75-77.e4.
Title: Validation of Recently Proposed Colorectal Cancer Susceptibility Gene Variants in an Analysis of Families and Patients-a Systematic Review.
Author: Broderick, Peter|Dobbins, Sara E|Chubb, Daniel|Kinnersley, Ben|Dunlop, Malcolm G|Tomlinson, Ian|Houlston, Richard S
PMID: 27713038
Journal: Int J Cancer. 2017 Oct 1;141(7):1365-1380.
Title: Elucidating the molecular basis of MSH2-deficient tumors by combined germline and somatic analysis.
Author: Vargas-Parra, Gardenia M|Gonzalez-Acosta, Maribel|Thompson, Bryony A|Gomez, Carolina|Fernandez, Anna|Damaso, Estela|Pons, Tirso|Morak, Monika|Del Valle, Jesus|Iglesias, Silvia|Velasco, Angela|Solanes, Ares|Sanjuan, Xavier|Padilla, Natalia|de la Cruz, Xavi
PMID: 28577310
Journal: Mol Cancer. 2018 Feb 15;17(1):23.
Title: Germline mutations in the spindle assembly checkpoint genes BUB1 and BUB3 are infrequent in familial colorectal cancer and polyposis.
Author: Mur, Pilar|De Voer, Richarda M|Olivera-Salguero, Ruben|Rodriguez-Perales, Sandra|Pons, Tirso|Setien, Fernando|Aiza, Gemma|Valdes-Mas, Rafael|Bertini, Angelo|Pineda, Marta|Vreede, Lilian|Navarro, Matilde|Iglesias, Silvia|Gonzalez, Sara|Brunet, Joan|Valenci
PMID: 29448935
Journal: Carcinogenesis. 2018 May 28;39(6):788-797.
Title: Mlh1 deficiency in normal mouse colon mucosa associates with chromosomally unstable colon cancer.
Author: Pussila, Marjaana|Toronen, Petri|Einarsdottir, Elisabet|Katayama, Shintaro|Krjutskov, Kaarel|Holm, Liisa|Kere, Juha|Peltomaki, Paivi|Makinen, Markus J|Linden, Jere|Nystrom, Minna
PMID: 29701748