Primary Site >> Colorectal Cancer

Gene >> BTRC

Journal: EMBO J. 1999 May 4;18(9):2401-10.
Title: An F-box protein, FWD1, mediates ubiquitin-dependent proteolysis of beta-catenin.
Author: Kitagawa, M|Hatakeyama, S|Shirane, M|Matsumoto, M|Ishida, N|Hattori, K|Nakamichi, I|Kikuchi, A|Nakayama, K|Nakayama, K
PMID: 10228155
Journal: BMC Mol Biol. 2003 Sep 29;4:10.
Title: A protein knockdown strategy to study the function of beta-catenin in tumorigenesis.
Author: Cong, Feng|Zhang, Jianxuan|Pao, William|Zhou, Pengbo|Varmus, Harold
PMID: 14516475
Journal: J Natl Cancer Inst. 2004 Aug 4;96(15):1161-70.
Title: Associations among beta-TrCP, an E3 ubiquitin ligase receptor, beta-catenin, and NF-kappaB in colorectal cancer.
Author: Ougolkov, Andrei|Zhang, Bin|Yamashita, Kaname|Bilim, Vladimir|Mai, Masayoshi|Fuchs, Serge Y|Minamoto, Toshinari
PMID: 15292388
Journal: Int J Mol Med. 2005 Sep;16(3):493-6.
Title: Comparative genomics on FGF8, FGF17, and FGF18 orthologs.
Author: Katoh, Masuko|Katoh, Masaru
PMID: 16077960
Journal: Genes Dev. 2006 Mar 1;20(5):586-600.
Title: The APC tumor suppressor counteracts beta-catenin activation and H3K4 methylation at Wnt target genes.
Author: Sierra, Jose|Yoshida, Tomonori|Joazeiro, Claudio A|Jones, Katherine A
PMID: 16510874
Journal: Nature. 2006 Jun 15;441(7095):898-901.
Title: CRD-BP mediates stabilization of betaTrCP1 and c-myc mRNA in response to beta-catenin signalling.
Author: Noubissi, Felicite K|Elcheva, Irina|Bhatia, Neehar|Shakoori, Abbas|Ougolkov, Andrei|Liu, Jianghuai|Minamoto, Toshinari|Ross, Jeff|Fuchs, Serge Y|Spiegelman, Vladimir S
PMID: 16778892
Journal: J Biochem. 2009 Mar;145(3):289-97.
Title: Beta-catenin induces beta-TrCP-mediated PER2 degradation altering circadian clock gene expression in intestinal mucosa of ApcMin/+ mice.
Author: Yang, Xiaoming|Wood, Patricia A|Ansell, Christine M|Ohmori, Masami|Oh, Eun-Yeong|Xiong, Yin|Berger, Franklin G|Pena, Maria Marjorette O|Hrushesky, William J M
PMID: 19106159
Journal: J Biol Chem. 2009 May 8;284(19):13033-44.
Title: The F-box protein beta-TrCp1/Fbw1a interacts with p300 to enhance beta-catenin transcriptional activity.
Author: Kimbrel, Erin A|Kung, Andrew L
PMID: 19297328
Journal: Mol Cell Biol. 2009 Dec;29(23):6192-205.
Title: beta-TrCP-mediated ubiquitination and degradation of PHLPP1 are negatively regulated by Akt.
Author: Li, Xin|Liu, Jianyu|Gao, Tianyan
PMID: 19797085
Journal: Cell Cycle. 2010 Feb 1;9(3):450-5. Epub 2010 Feb 3.
Title: NEK11: linking CHK1 and CDC25A in DNA damage checkpoint signaling.
Author: Sorensen, Claus Storgaard|Melixetian, Marina|Klein, Ditte Kjaersgaard|Helin, Kristian
PMID: 20090422
Journal: Mol Carcinog. 2010 Feb;49(2):121-9.
Title: Association between activation of atypical NF-kappaB1 p105 signaling pathway and nuclear beta-catenin accumulation in colorectal carcinoma.
Author: Lauscher, Johannes C|Grone, Jorn|Dullat, Sonja|Hotz, Birgit|Ritz, Jorg-P|Steinhoff, Ulrich|Buhr, Heinz-J|Visekruna, Alexander
PMID: 20027638
Journal: Int J Oncol. 2011 Jul;39(1):235-43.
Title: Phosphorylation of beta-catenin results in lack of beta-catenin signaling in melanoma.
Author: Kuphal, Silke|Bosserhoff, Anja Katrin
PMID: 21584489
Journal: Bioorg Med Chem Lett. 2013 Nov 1;23(21):5814-20.
Title: Investigation of 3-aryl-pyrimido[5,4-e][1,2,4]triazine-5,7-diones as small molecule antagonists of beta-catenin/TCF transcription.
Author: Zeller, Jorg|Turbiak, Anjanette J|Powelson, Ian A|Lee, Surin|Sun, Duxin|Showalter, H D Hollis|Fearon, Eric R
PMID: 24060489
Journal: J Biol Chem. 2014 Mar 14;289(11):7730-7.
Title: Proteasome-dependent degradation of transcription factor activating enhancer-binding protein 4 (TFAP4) controls mitotic division.
Author: D'Annibale, Sara|Kim, Jihoon|Magliozzi, Roberto|Low, Teck Yew|Mohammed, Shabaz|Heck, Albert J R|Guardavaccaro, Daniele
PMID: 24500709
Journal: FEBS Lett. 2014 Nov 28;588(23):4334-41.
Title: TRIB2 inhibits Wnt/beta-Catenin/TCF4 signaling through its associated ubiquitin E3 ligases, beta-TrCP, COP1 and Smurf1, in liver cancer cells.
Author: Xu, Shanshan|Tong, Minghong|Huang, Jingqin|Zhang, Yue|Qiao, Yongxia|Weng, Wenhao|Liu, Weiwei|Wang, Jiayi|Sun, Fenyong
PMID: 25311538
Journal: Mol Cancer Res. 2015 Nov;13(11):1487-501.
Title: Structure, Dynamics, and Functionality of Tankyrase Inhibitor-Induced Degradasomes.
Author: Thorvaldsen, Tor Espen|Pedersen, Nina Marie|Wenzel, Eva M|Schultz, Sebastian W|Brech, Andreas|Liestol, Knut|Waaler, Jo|Krauss, Stefan|Stenmark, Harald
PMID: 26124443
Journal: Cancer Cell. 2015 Aug 10;28(2):183-97.
Title: ERK2-Dependent Phosphorylation of CSN6 Is Critical in Colorectal Cancer Development.
Author: Fang, Lekun|Lu, Weisi|Choi, Hyun Ho|Yeung, Sai-Ching J|Tung, Jung-Yu|Hsiao, Chwan-Deng|Fuentes-Mattei, Enrique|Menter, David|Chen, Chuangqi|Wang, Lei|Wang, Jianping|Lee, Mong-Hong
PMID: 26267535
Journal: Elife. 2015 Sep 3;4.
Title: FAK/PYK2 promotes the Wnt/beta-catenin pathway and intestinal tumorigenesis by phosphorylating GSK3beta.
Author: Gao, Chenxi|Chen, Guangming|Kuan, Shih-Fan|Zhang, Dennis Han|Schlaepfer, David D|Hu, Jing
PMID: 26274564
Journal: Cancer Cell. 2017 May 8;31(5):621-634.e6.
Title: TIAM1 Antagonizes TAZ/YAP Both in the Destruction Complex in the Cytoplasm and in the Nucleus to Inhibit Invasion of Intestinal Epithelial Cells.
Author: Diamantopoulou, Zoi|White, Gavin|Fadlullah, Muhammad Z H|Dreger, Marcel|Pickering, Karen|Maltas, Joe|Ashton, Garry|MacLeod, Ruth|Baillie, George S|Kouskoff, Valerie|Lacaud, Georges|Murray, Graeme I|Sansom, Owen J|Hurlstone, Adam F L|Malliri, Angeliki
PMID: 28416184
Journal: Cell Death Dis. 2018 May 1;9(5):456.
Title: Ube2s stabilizes beta-Catenin through K11-linked polyubiquitination to promote mesendoderm specification and colorectal cancer development.
Author: Li, Zhaoyan|Wang, Yan|Li, Yadan|Yin, Wanqi|Mo, Libin|Qian, Xianghao|Zhang, Yiran|Wang, Guifen|Bu, Fan|Zhang, Zhiling|Ren, Xiaofang|Zhu, Baochang|Niu, Chang|Xiao, Wei|Zhang, Weiwei
PMID: 29674637