Primary Site >> Colorectal Cancer

Gene >> BRD4

Journal: J Mol Med (Berl). 2012 May;90(5):587-95.
Title: Aberrant epigenetic regulation of bromodomain BRD4 in human colon cancer.
Author: Rodriguez, R M|Huidobro, C|Urdinguio, R G|Mangas, C|Soldevilla, B|Dominguez, G|Bonilla, F|Fernandez, A F|Fraga, M F
PMID: 22120039
Journal: Proc Natl Acad Sci U S A. 2012 May 1;109(18):6927-32.
Title: BRD4 is an atypical kinase that phosphorylates serine2 of the RNA polymerase II carboxy-terminal domain.
Author: Devaiah, Ballachanda N|Lewis, Brian A|Cherman, Natasha|Hewitt, Michael C|Albrecht, Brian K|Robey, Pamela G|Ozato, Keiko|Sims, Robert J 3rd|Singer, Dinah S
PMID: 22509028
Journal: Int J Mol Sci. 2015 Jan 16;16(1):1928-48.
Title: BRD4 inhibitor inhibits colorectal cancer growth and metastasis.
Author: Hu, Yuan|Zhou, Jieqiong|Ye, Fei|Xiong, Huabao|Peng, Liang|Zheng, Zihan|Xu, Feihong|Cui, Miao|Wei, Chengguo|Wang, Xinying|Wang, Zhongqiu|Zhu, Hongfa|Lee, Peng|Zhou, Mingming|Jiang, Bo|Zhang, David Y
PMID: 25603177
Journal: Drug Des Devel Ther. 2015 Oct 30;9:5851-62.
Title: Arsenic sulfide combined with JQ1, chemotherapy agents, or celecoxib inhibit gastric and colon cancer cell growth.
Author: Zhang, Lian|Tong, Yingying|Zhang, Xiuli|Pan, Minggui|Chen, Siyu
PMID: 26586936
Journal: J Clin Invest. 2016 Feb;126(2):639-52.
Title: CCAT1 is an enhancer-templated RNA that predicts BET sensitivity in colorectal cancer.
Author: McCleland, Mark L|Mesh, Kathryn|Lorenzana, Edward|Chopra, Vivek S|Segal, Ehud|Watanabe, Colin|Haley, Benjamin|Mayba, Oleg|Yaylaoglu, Murat|Gnad, Florian|Firestein, Ron
PMID: 26752646
Journal: Mol Cancer Ther. 2016 Jun;15(6):1217-26.
Title: Dual Targeting of Bromodomain and Extraterminal Domain Proteins, and WNT or MAPK Signaling, Inhibits c-MYC Expression and Proliferation of Colorectal Cancer Cells.
Author: Togel, Lars|Nightingale, Rebecca|Chueh, Anderly C|Jayachandran, Aparna|Tran, Hoanh|Phesse, Toby|Wu, Rui|Sieber, Oliver M|Arango, Diego|Dhillon, Amardeep S|Dawson, Mark A|Diez-Dacal, Beatriz|Gahman, Timothy C|Filippakopoulos, Panagis|Shiau, Andrew K|Mariad
PMID: 26983878
Journal: Tumori. 2017 Nov 15;103(Suppl. 1):e5-e8.
Title: Uncommon somatic mutations in metastatic NUT midline carcinoma.
Author: Cavalieri, Stefano|Stathis, Anastasios|Fabbri, Alessandra|Sonzogni, Angelica|Perrone, Federica|Tamborini, Elena|Pelosi, Giuseppe|de Braud, Filippo|Platania, Marco
PMID: 28967088
Journal: Oncotarget. 2017 Nov 14;8(64):108020-108030.
Title: Sequencing of Lynch syndrome tumors reveals the importance of epigenetic alterations.
Author: Porkka, Noora|Valo, Satu|Nieminen, Taina T|Olkinuora, Alisa|Maki-Nevala, Satu|Eldfors, Samuli|Peltomaki, Paivi
PMID: 29296220
Journal: Mol Cell Biol. 2018 May 15;38(11). pii: MCB.00573-17.
Title: Depletion of Mediator Kinase Module Subunits Represses Superenhancer-Associated Genes in Colon Cancer Cells.
Author: Kuuluvainen, Emilia|Domenech-Moreno, Eva|Niemela, Elina H|Makela, Tomi P
PMID: 29507187
Journal: Nucleic Acids Res. 2018 Jul 24. pii: 5057089.
Title: TIP60 represses activation of endogenous retroviral elements.
Author: Rajagopalan, Deepa|Tirado-Magallanes, Roberto|Bhatia, Shreshtha Sailesh|Teo, Wen Shiun|Sian, Stephanie|Hora, Shainan|Lee, Kwok Kin|Zhang, Yanzhou|Jadhav, Shweta Pradip|Wu, Yonghui|Gan, Yunn-Hwen|Karnani, Neerja|Benoukraf, Touati|Jha, Sudhakar
PMID: 30053221
Journal: Nat Struct Mol Biol. 2018 Aug;25(8):687-697.
Title: RNAs interact with BRD4 to promote enhanced chromatin engagement and transcription activation.
Author: Rahnamoun, Homa|Lee, Jihoon|Sun, Zhengxi|Lu, Hanbin|Ramsey, Kristen M|Komives, Elizabeth A|Lauberth, Shannon M
PMID: 30076409
Journal: Int J Biochem Cell Biol. 2018 Aug 29;104:1-8.
Title: PES1 is transcriptionally regulated by BRD4 and promotes cell proliferation and glycolysis in hepatocellular carcinoma.
Author: Fan, Ping|Wang, Bo|Meng, Zibo|Zhao, Jingyuan|Jin, Xin
PMID: 30172011