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Journal:
Title: BRCA1- and BRCA2-Associated Hereditary Breast and Ovarian Cancer
Author: Petrucelli, Nancie|Daly, Mary B|Pal, Tuya
PMID: 20301425
Journal: Cancer Res. 1995 Oct 15;55(20):4570-4.
Title: An integrated high-resolution physical map of the DPC/BRCA2 region at chromosome 13q12.
Author: Schutte, M|Rozenblum, E|Moskaluk, C A|Guan, X|Hoque, A T|Hahn, S A|da Costa, L T|de Jong, P J|Kern, S E
PMID: 7553631
Journal: Proc Natl Acad Sci U S A. 1995 Jun 20;92(13):5950-4.
Title: Identification by representational difference analysis of a homozygous deletion in pancreatic carcinoma that lies within the BRCA2 region.
Author: Schutte, M|da Costa, L T|Hahn, S A|Moskaluk, C|Hoque, A T|Rozenblum, E|Weinstein, C L|Bittner, M|Meltzer, P S|Trent, J M
PMID: 7597059
Journal: Nat Genet. 1996 Jun;13(2):241-4.
Title: Low incidence of BRCA2 mutations in breast carcinoma and other cancers.
Author: Teng, D H|Bogden, R|Mitchell, J|Baumgard, M|Bell, R|Berry, S|Davis, T|Ha, P C|Kehrer, R|Jammulapati, S|Chen, Q|Offit, K|Skolnick, M H|Tavtigian, S V|Jhanwar, S|Swedlund, B|Wong, A K|Kamb, A
PMID: 8640236
Journal: Nat Genet. 1996 May;13(1):117-9.
Title: A single BRCA2 mutation in male and female breast cancer families from Iceland with varied cancer phenotypes.
Author: Thorlacius, S|Olafsdottir, G|Tryggvadottir, L|Neuhausen, S|Jonasson, J G|Tavtigian, S V|Tulinius, H|Ogmundsdottir, H M|Eyfjord, J E
PMID: 8673089
Journal: Cancer Res. 1996 Oct 15;56(20):4575-7.
Title: Mutations in the BRCA2 gene in hepatocellular carcinomas.
Author: Katagiri, T|Nakamura, Y|Miki, Y
PMID: 8840963
Journal: J Med Genet. 1996 Nov;33(11):889-98.
Title: Pancreatic adenocarcinoma: epidemiology and genetics.
Author: Flanders, T Y|Foulkes, W D
PMID: 8950667
Journal: Cancer Res. 1996 Dec 1;56(23):5360-4.
Title: Germline BRCA2 gene mutations in patients with apparently sporadic pancreatic carcinomas.
Author: Goggins, M|Schutte, M|Lu, J|Moskaluk, C A|Weinstein, C L|Petersen, G M|Yeo, C J|Jackson, C E|Lynch, H T|Hruban, R H|Kern, S E
PMID: 8968085
Journal: Nat Genet. 1997 Jan;15(1):103-5.
Title: Variation of risks of breast and ovarian cancer associated with different germline mutations of the BRCA2 gene.
Author: Gayther, S A|Mangion, J|Russell, P|Seal, S|Barfoot, R|Ponder, B A|Stratton, M R|Easton, D
PMID: 8988179
Journal: Mol Med Today. 1997 Apr;3(4):168-74.
Title: Mutations of the BRCA1 and BRCA2 genes and the possibilities for predictive testing.
Author: Gayther, S A|Ponder, B A
PMID: 9134530
Journal: Nat Genet. 1997 May;16(1):17-8.
Title: Germline BRCA2 6174delT mutations in Ashkenazi Jewish pancreatic cancer patients.
Author: Ozcelik, H|Schmocker, B|Di Nicola, N|Shi, X H|Langer, B|Moore, M|Taylor, B R|Narod, S A|Darlington, G|Andrulis, I L|Gallinger, S|Redston, M
PMID: 9140390
Journal: Am J Hum Genet. 1997 May;60(5):1079-84.
Title: Study of a single BRCA2 mutation with high carrier frequency in a small population.
Author: Thorlacius, S|Sigurdsson, S|Bjarnadottir, H|Olafsdottir, G|Jonasson, J G|Tryggvadottir, L|Tulinius, H|Eyfjord, J E
PMID: 9150155
Journal: Digestion. 1997;58(6):550-6.
Title: Molecular advances in pancreatic cancer.
Author: Lemoine, N R
PMID: 9438601
Journal: Digestion. 1997;58(6):564-9.
Title: Hereditary pancreatitis and familial pancreatic cancer.
Author: Finch, M D|Howes, N|Ellis, I|Mountford, R|Sutton, R|Raraty, M|Neoptolemos, J P
PMID: 9438603
Journal: Breast Cancer. 1997 Dec 25;4(4):256-258.
Title: BRCA1 and BRCA2 Germline Mutations in Japanese with Hereditary Breast Cancer Families.
Author: Fukutomi|Ushijima|Inoue|Akashi-Tanaka|Nanasawa|Tsuda
PMID: 11091610
Journal: Surg Oncol Clin N Am. 1998 Jan;7(1):1-23.
Title: Genetics of pancreatic cancer. From genes to families.
Author: Hruban, R H|Petersen, G M|Ha, P K|Kern, S E
PMID: 9443984
Journal: Proc Natl Acad Sci U S A. 1998 Apr 28;95(9):5287-92.
Title: The BRC repeats in BRCA2 are critical for RAD51 binding and resistance to methyl methanesulfonate treatment.
Author: Chen, P L|Chen, C F|Chen, Y|Xiao, J|Sharp, Z D|Lee, W H
PMID: 9560268
Journal: Cancer Res. 1998 Jun 1;58(11):2339-42.
Title: Alterations in pancreatic, biliary, and breast carcinomas support MKK4 as a genetically targeted tumor suppressor gene.
Author: Su, G H|Hilgers, W|Shekher, M C|Tang, D J|Yeo, C J|Hruban, R H|Kern, S E
PMID: 9622070
Journal: J Natl Cancer Inst. 1999 Aug 4;91(15):1310-6.
Title: Cancer risks in BRCA2 mutation carriers.
Author:
PMID: 10433620
Journal: Ann Oncol. 1999;10 Suppl 4:4-8.
Title: Progress in cancer genetics: lessons from pancreatic cancer.
Author: Goggins, M|Kern, S E|Offerhaus, J A|Hruban, R H
PMID: 10436774
Journal: Ann Oncol. 1999;10 Suppl 4:9-11.
Title: Pathology of incipient pancreatic cancer.
Author: Hruban, R H|Wilentz, R E|Goggins, M|Offerhaus, G J|Yeo, C J|Kern, S E
PMID: 10436775
Journal: Ann Oncol. 1999;10 Suppl 4:69-73.
Title: Familial pancreatic cancer.
Author: Hruban, R H|Petersen, G M|Goggins, M|Tersmette, A C|Offerhaus, G J|Falatko, F|Yeo, C J|Kern, S E
PMID: 10436789
Journal: Curr Opin Gastroenterol. 1999 Sep;15(5):404-9.
Title: Molecular genetics and related developments in pancreatic cancer.
Author: Hruban, R H|Goggins, M|Kern, S E
PMID: 17023981
Journal: Cancer Res. 2000 Jan 15;60(2):409-16.
Title: Inherited predisposition to pancreatic adenocarcinoma: role of family history and germ-line p16, BRCA1, and BRCA2 mutations.
Author: Lal, G|Liu, G|Schmocker, B|Kaurah, P|Ozcelik, H|Narod, S A|Redston, M|Gallinger, S
PMID: 10667595
Journal: Am J Pathol. 2000 May;156(5):1767-71.
Title: BRCA2 is inactivated late in the development of pancreatic intraepithelial neoplasia: evidence and implications.
Author: Goggins, M|Hruban, R H|Kern, S E
PMID: 10793087
Journal: Pancreas. 2000 Nov;21(4):369-75.
Title: Multiple primary tumors as an indicator for p16INK4a germline mutations in pancreatic cancer patients?
Author: Gerdes, B|Bartsch, D K|Ramaswamy, A|Kersting, M|Wild, A|Schuermann, M|Frey, M|Rothmund, M
PMID: 11075991
Journal: Curr Opin Gastroenterol. 2000 Sep;16(5):419-25.
Title: Molecular genetics of ductal pancreatic neoplasia.
Author: Su, G H|Kern, S E
PMID: 17031113
Journal: Cancer Res. 2001 Jan 1;61(1):270-7.
Title: Nonhomologous end-joining of ionizing radiation-induced DNA double-stranded breaks in human tumor cells deficient in BRCA1 or BRCA2.
Author: Wang, H|Zeng, Z C|Bui, T A|DiBiase, S J|Qin, W|Xia, F|Powell, S N|Iliakis, G
PMID: 11196174
Journal: Br J Cancer. 2001 Feb;84(4):478-81.
Title: The rate of the 6174delT founder Jewish mutation in BRCA2 in patients with non-colonic gastrointestinal tract tumours in Israel.
Author: Figer, A|Irmin, L|Geva, R|Flex, D|Sulkes, J|Sulkes, A|Friedman, E
PMID: 11207041
Journal: Dig Dis. 2001;19(1):76-84.
Title: Prevention of pancreatic cancer and strategies for management of familial pancreatic cancer.
Author: Hruban, R H|Canto, M I|Yeo, C J
PMID: 11385254
Journal: Hepatogastroenterology. 2001 Jul-Aug;48(40):933-8.
Title: Molecular diagnosis of pancreatic cancer.
Author: Inoue, S|Tezel, E|Nakao, A
PMID: 11490843
Journal: Cancer J. 2001 Jul-Aug;7(4):266-73.
Title: Familial pancreatic cancer.
Author: Klein, A P|Hruban, R H|Brune, K A|Petersen, G M|Goggins, M
PMID: 11561603
Journal: Pancreatology. 2001;1(5):466-71.
Title: Hereditary pancreatic cancer.
Author: Lynch, H T|Brand, R E|Deters, C A|Shaw, T G|Lynch, J F
PMID: 12120226
Journal: Pancreatology. 2001;1(5):510-6.
Title: Update of familial pancreatic cancer in Germany.
Author: Bartsch, D K|Sina-Frey, M|Ziegler, A|Hahn, S A|Przypadlo, E|Kress, R|Gerdes, B|Rieder, H
PMID: 12120230
Journal: Pancreatology. 2001;1(6):571-5.
Title: Pancreatic cancer genetics.
Author: Efthimiou, E|Crnogorac-Jurcevic, T|Lemoine, N R
PMID: 12120238
Journal: Asian Pac J Cancer Prev. 2001;2(4):271-280.
Title: An Epidemiological Overview of Environmental and Genetic Risk Factors of Pancreatic Cancer.
Author: Lin, Yingsong|Tamakoshi, Akiko|Kawamura, Takashi|Inaba, Yutaka|Kikuchi, Shogo|Motohashi, Yutaka|Kurosawa, Michiko|Ohno, Yoshiyuki
PMID: 12718618
Journal: Breast Cancer Res. 2002;4(1):R2. Epub 2001 Nov 21.
Title: BRCA1 and BRCA2 mutations in a population-based study of male breast cancer.
Author: Basham, Victoria M|Lipscombe, Julian M|Ward, Joanna M|Gayther, Simon A|Ponder, Bruce A J|Easton, Douglas F|Pharoah, Paul D P
PMID: 11879560
Journal: Cancer Res. 2002 Mar 1;62(5):1311-4.
Title: Inhibition of cancer cell growth by BRCA2.
Author: Wang, Shao-Chun|Shao, Ruping|Pao, Annie Y|Zhang, Su|Hung, Mien-Chie|Su, Li-Kuo
PMID: 11888897
Journal: Gut. 2002 May;50(5):653-7.
Title: Family history of cancer and germline BRCA2 mutations in sporadic exocrine pancreatic cancer.
Author: Real, F X|Malats, N|Lesca, G|Porta, M|Chopin, S|Lenoir, G M|Sinilnikova, O
PMID: 11950811
Journal: Nihon Geka Gakkai Zasshi. 2002 Jun;103(6):476-81.
Title: [Genetics of pancreatic cancer: recent advances in molecular diagnosis].
Author: Hayashi, Naoko|Egami, Hiroshi|Ogawa, Michio
PMID: 12094699
Journal: Cancer Res. 2002 Jul 1;62(13):3789-93.
Title: Evaluation of candidate genes MAP2K4, MADH4, ACVR1B, and BRCA2 in familial pancreatic cancer: deleterious BRCA2 mutations in 17%.
Author: Murphy, Kathleen M|Brune, Kieran A|Griffin, Constance|Sollenberger, Jennifer E|Petersen, Gloria M|Bansal, Ravi|Hruban, Ralph H|Kern, Scott E
PMID: 12097290
Journal: Onkologie. 2002 Jun;25(3):262-6.
Title: German national case collection of familial pancreatic cancer - clinical-genetic analysis of the first 21 families.
Author: Rieder, H|Sina-Frey, M|Ziegler, A|Hahn, S A|Przypadlo, E|Kress, R|Gerdes, B|Colombo Benkmann, M|Eberl, T|Grutzmann, R|Lorken, M|Schmidt, J|Bartsch, D K
PMID: 12119461
Journal: Genet Epidemiol. 2002 Aug;23(2):133-49.
Title: Evidence for a major gene influencing risk of pancreatic cancer.
Author: Klein, Alison P|Beaty, Terri H|Bailey-Wilson, Joan E|Brune, Kieran A|Hruban, Ralph H|Petersen, Gloria M
PMID: 12214307
Journal: Oncology (Williston Park). 2002 Dec;16(12):1615-22, 1631-2; discussion 1632-3,
Title: Pancreatic cancer: epidemiology, genetics, and approaches to screening.
Author: Konner, Jason|O'Reilly, Eileen
PMID: 12520639
Journal: Pathology. 2002 Dec;34(6):504-17.
Title: Premalignant conditions of the pancreas.
Author: Hall, Pauline de la M|Wilentz, Robb E|de Klerk, Willouw|Bornman, Philippus P C
PMID: 12555988
Journal: Int J Gastrointest Cancer. 2002;31(1-3):99-106.
Title: BRCA2 and pancreatic cancer.
Author: Naderi, Ali|Couch, Fergus J
PMID: 12622420
Journal: J Natl Cancer Inst. 2003 Feb 5;95(3):214-21.
Title: BRCA2 germline mutations in familial pancreatic carcinoma.
Author: Hahn, Stephan A|Greenhalf, Bill|Ellis, Ian|Sina-Frey, Mercedes|Rieder, Harald|Korte, Birgit|Gerdes, Berthold|Kress, Ralf|Ziegler, Andreas|Raeburn, John A|Campra, Donata|Grutzmann, Robert|Rehder, Helga|Rothmund, Matthias|Schmiegel, Wolff|Neoptolemos, John
PMID: 12569143
Journal: Cancer Detect Prev. 2003;27(2):87-93.
Title: Epidemiology of pancreatic cancer: an overview.
Author: Ghadirian, P|Lynch, H T|Krewski, D
PMID: 12670518
Journal: Cancer Res. 2003 May 15;63(10):2585-8.
Title: Fanconi anemia gene mutations in young-onset pancreatic cancer.
Author: van der Heijden, Michiel S|Yeo, Charles J|Hruban, Ralph H|Kern, Scott E
PMID: 12750283
Journal: J Natl Cancer Inst. 2003 Jul 2;95(13):948-60.
Title: Etiology of pancreatic cancer, with a hypothesis concerning the role of N-nitroso compounds and excess gastric acidity.
Author: Risch, Harvey A
PMID: 12837831
Journal: Cancer Biol Ther. 2004 Feb;3(2):167-9. Epub 2004 Feb 1.
Title: The genetics of FANCC and FANCG in familial pancreatic cancer.
Author: Rogers, Carmelle D|van der Heijden, Michiel S|Brune, Kieran|Yeo, Charles J|Hruban, Ralph H|Kern, Scott E|Goggins, Michael
PMID: 14726700
Journal: J Clin Oncol. 2004 Feb 15;22(4):735-42.
Title: Cancer risks for male carriers of germline mutations in BRCA1 or BRCA2: a review of the literature.
Author: Liede, Alexander|Karlan, Beth Y|Narod, Steven A
PMID: 14966099
Journal: Oncogene. 2004 Mar 11;23(10):1896-901.
Title: A delayed chemically induced tumorigenesis in Brca2 mutant mice.
Author: Yan, Duen-Hwa|Wen, Yong|Su, Li-Kuo|Xia, Weiya|Wang, Shao-Chun|Zhang, Su|Gan, Lin|Lee, Dung-Fang|Spohn, Bill|Frey, Jennifer A|Hortobagyi, Gabriel N|Hung, Mien-Chie
PMID: 14981540
Journal: Cancer Biol Ther. 2004 Jun;3(6):534-7. Epub 2004 Jun 18.
Title: Functional screen of the fanconi anemia pathway in cancer cells by Fancd2 immunoblot.
Author: Van Der Heijden, Michiel S|Brody, Jonathan R|Kern, Scott E
PMID: 15107617
Journal: Cancer Biol Ther. 2004 Jun;3(6):534-7. Epub 2004 Jun 18.
Title: Functional screen of the fanconi anemia pathway in cancer cells by Fancd2 immunoblot.
Author: Van Der Heijden, Michiel S|Brody, Jonathan R|Kern, Scott E
PMID: 15107817
Journal: Cancer. 2004 May 1;100(9):1978-86.
Title: Characterization of FAMPAC, a newly identified human pancreatic carcinoma cell line with a hereditary background.
Author: Eisold, Sven|Ryschich, Eduard|Linnebacher, Michael|Giese, Thomas|Nauheimer, Dirk|Wild, Anja|Bartsch, Detlef K|Buchler, Markus W|Schmidt, Jan
PMID: 15112280
Journal: Fam Cancer. 2004;3(1):1-10.
Title: Cancer variation associated with the position of the mutation in the BRCA2 gene.
Author: Lubinski, Jan|Phelan, Catherine M|Ghadirian, Parviz|Lynch, Henry T|Garber, Judy|Weber, Barbara|Tung, Nadine|Horsman, Douglas|Isaacs, Claudine|Monteiro, Alvaro N A|Sun, Ping|Narod, Steven A
PMID: 15131399
Journal: Cytogenet Genome Res. 2004;104(1-4):333-40.
Title: Possible causes of chromosome instability: comparison of chromosomal abnormalities in cancer cell lines with mutations in BRCA1, BRCA2, CHK2 and BUB1.
Author: Grigorova, M|Staines, J M|Ozdag, H|Caldas, C|Edwards, P A W
PMID: 15162061
Journal: Clin Cancer Res. 2004 Jun 1;10(11):3780-7.
Title: Down-regulation of BRCA1 in chronic pancreatitis and sporadic pancreatic adenocarcinoma.
Author: Beger, Carmela|Ramadani, Marco|Meyer, Stephan|Leder, Gerd|Kruger, Martin|Welte, Karl|Gansauge, Frank|Beger, Hans G
PMID: 15173085
Journal: Breast Cancer Res. 2004;6(4):R366-71. Epub 2004 May 14.
Title: No germline mutations in the histone acetyltransferase gene EP300 in BRCA1 and BRCA2 negative families with breast cancer and gastric, pancreatic, or colorectal cancer.
Author: Campbell, Ian G|Choong, David|Chenevix-Trench, Georgia
PMID: 15217503
Journal: Jpn J Clin Oncol. 2004 May;34(5):238-44.
Title: Epidemiology and prevention of pancreatic cancer.
Author: Lowenfels, Albert B|Maisonneuve, Patrick
PMID: 15231857
Journal: Am J Med Genet C Semin Med Genet. 2004 Aug 15;129C(1):5-22.
Title: Inherited predisposition to cancer: a historical overview.
Author: Lynch, Henry T|Shaw, Trudy G|Lynch, Jane F
PMID: 15264268
Journal: Am J Pathol. 2004 Aug;165(2):651-7.
Title: Functional defects in the fanconi anemia pathway in pancreatic cancer cells.
Author: van der Heijden, Michiel S|Brody, Jonathan R|Gallmeier, Eike|Cunningham, Steven C|Dezentje, David A|Shen, Dong|Hruban, Ralph H|Kern, Scott E
PMID: 15277238
Journal: Fam Cancer. 2004;3(3-4):233-40.
Title: Familial pancreatic carcinoma in Jews.
Author: Lynch, Henry T|Deters, Carolyn A|Lynch, Jane F|Brand, Randall E
PMID: 15516847
Journal: Ann Oncol. 2004 Dec;15(12):1834-41.
Title: Risk of cancer at sites other than the breast in Swedish families eligible for BRCA1 or BRCA2 mutation testing.
Author: Lorenzo Bermejo, J|Hemminki, K
PMID: 15550590
Journal: Methods Mol Med. 2005;103:329-41.
Title: Overview of linkage analysis: application to pancreatic cancer.
Author: Klein, Alison P
PMID: 15542915
Journal: Cancer Res. 2005 Jan 15;65(2):383-6.
Title: Germ line Fanconi anemia complementation group C mutations and pancreatic cancer.
Author: Couch, Fergus J|Johnson, Michele R|Rabe, Kari|Boardman, Lisa|McWilliams, Robert|de Andrade, Mariza|Petersen, Gloria
PMID: 15695377
Journal: Cancer Res. 2005 Mar 15;65(6):2260-8.
Title: Tbx2 is overexpressed and plays an important role in maintaining proliferation and suppression of senescence in melanomas.
Author: Vance, Keith W|Carreira, Suzanne|Brosch, Gerald|Goding, Colin R
PMID: 15781639
Journal: Cancer Genet Cytogenet. 2005 Apr 15;158(2):119-25.
Title: BRCA1 and pancreatic cancer: pedigree findings and their causal relationships.
Author: Lynch, Henry T|Deters, Carolyn A|Snyder, Carrie L|Lynch, Jane F|Villeneuve, Pierre|Silberstein, Julie|Martin, Holly|Narod, Steven A|Brand, Randall E
PMID: 15796958
Journal: Oncogene. 2005 May 19;24(22):3652-6.
Title: Increased prevalence of the BRCA2 polymorphic stop codon K3326X among individuals with familial pancreatic cancer.
Author: Martin, Sean T|Matsubayashi, Hiroyuki|Rogers, Carmelle D|Philips, Juliet|Couch, Fergus J|Brune, Kieran|Yeo, Charles J|Kern, Scott E|Hruban, Ralph H|Goggins, Michael
PMID: 15806175
Journal: J Cell Biochem. 2005 Jul 1;95(4):649-56.
Title: Risk factors for pancreatic cancer.
Author: Lowenfels, Albert B|Maisonneuve, Patrick
PMID: 15849724
Journal: Curr Treat Options Gastroenterol. 2005 Oct;8(5):365-75.
Title: Treatment of familial pancreatic cancer and its precursors.
Author: Hruban, Ralph H|Canto, Marcia I|Griffin, Constance|Kern, Scott E|Klein, Alison P|Laheru, Dan|Yeo, Charles J
PMID: 16162302
Journal: Semin Radiat Oncol. 2005 Oct;15(4):254-64.
Title: Ductal neoplasia of the pancreas: nosologic, clinicopathologic, and biologic aspects.
Author: Adsay, Nazmi Volkan|Basturk, Olca|Cheng, Jeanette D|Andea, Aleodor A
PMID: 16183479
Journal: Clin Cancer Res. 2005 Oct 15;11(20):7508-15.
Title: In vivo therapeutic responses contingent on Fanconi anemia/BRCA2 status of the tumor.
Author: van der Heijden, Michiel S|Brody, Jonathan R|Dezentje, David A|Gallmeier, Eike|Cunningham, Steven C|Swartz, Michael J|DeMarzo, Angelo M|Offerhaus, G Johan A|Isacoff, William H|Hruban, Ralph H|Kern, Scott E
PMID: 16243825
Journal: BMC Genet. 2006 Jan 17;7:3.
Title: Does tumorigenesis select for or against mutations of the DNA repair-associated genes BRCA2 and MRE11?: considerations from somatic mutations in microsatellite unstable (MSI) gastrointestinal cancers.
Author: van der Heijden, Michiel S|Brody, Jonathan R|Elghalbzouri-Maghrani, Elhaam|Zdzienicka, Malgorzata Z|Kern, Scott E
PMID: 16417627
Journal: Endocrinol Metab Clin North Am. 2006 Jun;35(2):417-30, xi.
Title: Familial pancreatic cancer syndromes.
Author: Habbe, Nils|Langer, Peter|Sina-Frey, Mercedes|Bartsch, Detlef K
PMID: 16632103
Journal: Mol Cancer Ther. 2006 Apr;5(4):787-96.
Title: Molecular biomarkers: their increasing role in the diagnosis, characterization, and therapy guidance in pancreatic cancer.
Author: Jimeno, Antonio|Hidalgo, Manuel
PMID: 16648548
Journal: Magy Onkol. 2006;50(2):163-8.
Title: [Familial pancreatic cancer].
Author: Zalatnai, Attila
PMID: 16888680
Journal: Oncogene. 2007 Mar 8;26(11):1626-35. Epub 2006 Sep 11.
Title: Characterizing a rat Brca2 knockout model.
Author: Cotroneo, M S|Haag, J D|Zan, Y|Lopez, C C|Thuwajit, P|Petukhova, G V|Camerini-Otero, R D|Gendron-Fitzpatrick, A|Griep, A E|Murphy, C J|Dubielzig, R R|Gould, M N
PMID: 16964288
Journal: Gut. 2007 May;56(5):601-5. Epub 2006 Sep 14.
Title: Role of BRCA1 and BRCA2 mutations in pancreatic cancer.
Author: Greer, Julia B|Whitcomb, David C
PMID: 16973716
Journal: Clin Cancer Res. 2007 Feb 1;13(3):839-43.
Title: Germline mutations in the BRCA2 gene and susceptibility to hereditary prostate cancer.
Author: Agalliu, Ilir|Kwon, Erika M|Zadory, Daniel|McIntosh, Laura|Thompson, Joseph|Stanford, Janet L|Ostrander, Elaine A
PMID: 17289875
Journal: Cancer Epidemiol Biomarkers Prev. 2007 Feb;16(2):342-6.
Title: The prevalence of BRCA2 mutations in familial pancreatic cancer.
Author: Couch, Fergus J|Johnson, Michele R|Rabe, Kari G|Brune, Kieran|de Andrade, Mariza|Goggins, Michael|Rothenmund, Heidi|Gallinger, Steven|Klein, Alison|Petersen, Gloria M|Hruban, Ralph H
PMID: 17301269
Journal: Cancer Biol Ther. 2007 Mar;6(3):320-3. Epub 2007 Mar 15.
Title: Linkage analysis of chromosome 4 in families with familial pancreatic cancer.
Author: Klein, Alison P|de Andrade, Mariza|Hruban, Ralph H|Bondy, Melissa|Schwartz, Ann G|Gallinger, Steven|Lynch, Henry T|Syngal, Sapna|Rabe, Kari G|Goggins, Michael G|Petersen, Gloria M
PMID: 17312386
Journal: Cancer. 2007 May 1;109(9):1784-90.
Title: Prophylactic salpingo-oophorectomy in a series of 89 women carrying a BRCA1 or a BRCA2 mutation.
Author: Laki, Fatima|Kirova, Youlia M|This, Pascale|Plancher, Corinne|Asselain, Bernard|Sastre, Xavier|Stoppa-Lyonnet, Dominique|Salmon, Remy
PMID: 17351952
Journal: J Hepatobiliary Pancreat Surg. 2007;14(3):224-32. Epub 2007 May 29.
Title: Molecular genetics of pancreatic intraepithelial neoplasia.
Author: Feldmann, Georg|Beaty, Robert|Hruban, Ralph H|Maitra, Anirban
PMID: 17520196
Journal: Pancreatology. 2007;7(5-6):459-69. Epub 2007 Oct 1.
Title: Cancer risk among the relatives of patients with pancreatic ductal adenocarcinoma.
Author: Del Chiaro, Marco|Zerbi, Alessandro|Falconi, Massimo|Bertacca, Laura|Polese, Marco|Sartori, Nora|Boggi, Ugo|Casari, Giorgio|Longoni, Bianca Maria|Salvia, Roberto|Caligo, Maria Adelaide|Di Carlo, Valerio|Pederzoli, Paolo|Presciuttini, Silvano|Mosca, Franco
PMID: 17912010
Journal: Expert Rev Gastroenterol Hepatol. 2007 Oct;1(1):81-8.
Title: Familial pancreatic cancer: from genes to improved patient care.
Author: Hruban, Ralph H|Klein, Alison P|Eshleman, James R|Axilbund, Jennifer E|Goggins, Michael
PMID: 19072437
Journal: Expert Opin Med Diagn. 2007 Oct;1(2):193-201.
Title: Familial pancreatic cancer: current status.
Author: Langer, Peter|Slater, Emily|Fendrich, Volker|Habbe, Nils|Bartsch, Detlef K
PMID: 23489306
Journal: Nature. 2008 Feb 28;451(7182):1111-5.
Title: Resistance to therapy caused by intragenic deletion in BRCA2.
Author: Edwards, Stacey L|Brough, Rachel|Lord, Christopher J|Natrajan, Rachael|Vatcheva, Radost|Levine, Douglas A|Boyd, Jeff|Reis-Filho, Jorge S|Ashworth, Alan
PMID: 18264088
Journal: Cancer Res. 2008 Feb 15;68(4):971-5.
Title: Mutational analysis of thirty-two double-strand DNA break repair genes in breast and pancreatic cancers.
Author: Wang, Xianshu|Szabo, Csilla|Qian, Chiping|Amadio, Peter G|Thibodeau, Stephen N|Cerhan, James R|Petersen, Gloria M|Liu, Wanguo|Couch, Fergus J
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Journal: Br J Cancer. 2008 Apr 22;98(8):1457-66.
Title: The BOADICEA model of genetic susceptibility to breast and ovarian cancers: updates and extensions.
Author: Antoniou, A C|Cunningham, A P|Peto, J|Evans, D G|Lalloo, F|Narod, S A|Risch, H A|Eyfjord, J E|Hopper, J L|Southey, M C|Olsson, H|Johannsson, O|Borg, A|Pasini, B|Radice, P|Manoukian, S|Eccles, D M|Tang, N|Olah, E|Anton-Culver, H|Warner, E|Lubinski, J|Gronw
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Journal: Pancreas. 2008 May;36(4):337-40.
Title: BRCA2 mutations as a universal risk factor for pancreatic cancer has a limited role in Korean ethnic group.
Author: Cho, Jae Hee|Bang, Seungmin|Park, Seung Woo|Chung, Jae Bock|Song, Si Young
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Journal: Genet Test. 2008 Jun;12(2):267-71.
Title: Predominant Ashkenazi BRCA1/2 mutations in families with pancreatic cancer.
Author: Dagan, Efrat
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Journal: Eur J Gastroenterol Hepatol. 2008 Aug;20(8):713-5.
Title: Pancreatic cancer: a plea for good and comprehensive morphological studies.
Author: Algul, Hana|Schmid, Roland M
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Journal: Breast. 2008 Oct;17(5):441-50.
Title: Counseling for male BRCA mutation carriers: a review.
Author: Mohamad, Hussain B|Apffelstaedt, Justus P
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Journal: Gastrointest Endosc Clin N Am. 2008 Jul;18(3):535-53, x.
Title: Screening and surveillance approaches in familial pancreatic cancer.
Author: Canto, Marcia Irene
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Journal: Hum Genet. 2008 Oct;124(3):271-8.
Title: Germline BRCA1 mutations predispose to pancreatic adenocarcinoma.
Author: Al-Sukhni, Wigdan|Rothenmund, Heidi|Borgida, Ayelet Eppel|Zogopoulos, George|O'Shea, Anne-Marie|Pollett, Aaron|Gallinger, Steven
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Journal: Int J Clin Exp Pathol. 2008 Jan 1;1(4):343-51.
Title: Amplification of EMSY gene in a subset of sporadic pancreatic adenocarcinomas.
Author: van Hattem, W Arnout|Carvalho, Ralph|Li, Ang|Offerhaus, G Johan A|Goggins, Michael
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Journal: Pancreatology. 2008;8(6):558-65.
Title: International registries of families at high risk of pancreatic cancer.
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Journal: Pol Arch Med Wewn. 2008 Nov;118(11):645-9.
Title: Is there any relationship between BRCA1 gene mutation and pancreatic cancer development?
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Journal: Fam Cancer. 2009;8(2):153-8.
Title: Prevalence and characteristics of pancreatic cancer in families with BRCA1 and BRCA2 mutations.
Author: Kim, Daniel H|Crawford, Beth|Ziegler, John|Beattie, Mary S
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Journal: Mutat Res. 2009 Apr 26;663(1-2):84-9.
Title: cDNA analysis demonstrates that the BRCA2 intronic variant IVS4-12del5 is a deleterious mutation.
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Journal: Mutat Res. 2009 Mar-Jun;681(2-3):299-307.
Title: Genetic predisposition and environmental risk factors to pancreatic cancer: A review of the literature.
Author: Landi, Stefano
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Journal: Arch Pathol Lab Med. 2009 Mar;133(3):365-74.
Title: Familial pancreatic cancer.
Author: Shi, Chanjuan|Hruban, Ralph H|Klein, Alison P
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Journal: PLoS One. 2009;4(3):e4812.
Title: Potential excess mortality in BRCA1/2 mutation carriers beyond breast, ovarian, prostate, and pancreatic cancers, and melanoma.
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Title: Prolonged survival in a patient with BRCA2 associated metastatic pancreatic cancer after exposure to camptothecin: a case report and review of literature.
Author: James, Edward|Waldron-Lynch, Maeve G|Saif, Muhammad Wasif
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Journal: Am J Gastroenterol. 2009 Sep;104(9):2175-81.
Title: The yield of first-time endoscopic ultrasonography in screening individuals at a high risk of developing pancreatic cancer.
Author: Poley, J W|Kluijt, I|Gouma, D J|Harinck, F|Wagner, A|Aalfs, C|van Eijck, C H J|Cats, A|Kuipers, E J|Nio, Y|Fockens, P|Bruno, M J
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Journal: Gastroenterology. 2009 Sep;137(3):1183-6.
Title: Analysis of the gene coding for the BRCA2-interacting protein PALB2 in familial and sporadic pancreatic cancer.
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Journal: Cancer Epidemiol Biomarkers Prev. 2009 Sep;18(9):2549-52.
Title: Polymorphic variants in hereditary pancreatic cancer genes are not associated with pancreatic cancer risk.
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Journal: J Laparoendosc Adv Surg Tech A. 2009 Dec;19(6):771-5.
Title: Robotic resection of intraductal neoplasm of the pancreas.
Author: Machado, Marcel A C|Makdissi, Fabio F|Surjan, Rodrigo C|Abdalla, Ricardo Z
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Journal: Mayo Clin Proc. 2009 Sep;84(9):801-10.
Title: Fluorescence in situ hybridization to visualize genetic abnormalities in interphase cells of acinar cell carcinoma, ductal adenocarcinoma, and islet cell carcinoma of the pancreas.
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Journal: Br J Cancer. 2009 Nov 17;101(10):1792-7.
Title: Familial association of pancreatic cancer with other malignancies in Swedish families.
Author: Hiripi, E|Lorenzo Bermejo, J|Li, X|Sundquist, J|Hemminki, K
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Journal: Clin Gastroenterol Hepatol. 2009 Nov;7(11 Suppl):S55-8.
Title: Differentiating neoplastic from benign lesions of the pancreas: translational techniques.
Author: Khalid, Asif
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Journal: Eur J Gynaecol Oncol. 2009;30(6):661-3.
Title: Incidence of multiple primary malignancies in women diagnosed with breast cancer.
Author: Stracci, F|D'Alo, D|Cassetti, T|Scheibel, M|La Rosa, F
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Journal: Clin Genet. 2010 Apr;77(4):333-41.
Title: Clinical and genetic analysis of 18 pancreatic carcinoma/melanoma-prone families.
Author: Bartsch, D K|Langer, P|Habbe, N|Matthai, E|Chaloupka, B|Sina, M|Hahn, S A|Slater, E P
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Journal: Fam Cancer. 2010 Sep;9(3):335-43.
Title: Prevalence of BRCA2 and CDKN2a mutations in German familial pancreatic cancer families.
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Journal: Expert Opin Drug Deliv. 2010 Mar;7(3):273-84.
Title: Identifying pancreatic cancer patients for targeted treatment: the challenges and limitations of the current selection process and vision for the future.
Author: Showalter, Shayna L|Charles, Sarah|Belin, Justin|Cozzitorto, Joseph|Einstein, Peter|Richards, Nathan G|Sauter, Patricia K|Kennedy, Eugene P|Witkiewicz, Agnes|Brody, Jonathan R|Yeo, Charles J
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Journal: Clin Cancer Res. 2010 Jun 15;16(12):3171-81.
Title: Aurora kinase A promotes ovarian tumorigenesis through dysregulation of the cell cycle and suppression of BRCA2.
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Title: Pancreatic cancer risk counselling and screening: impact on perceived risk and psychological functioning.
Author: Maheu, Christine|Vodermaier, Andrea|Rothenmund, Heidi|Gallinger, Steve|Ardiles, Paola|Semotiuk, Kara|Holter, Spring|Thayalan, Saumea|Esplen, Mary Jane
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Journal: Cancer Res. 2010 Oct 1;70(19):7353-9.
Title: PALB2/FANCN: recombining cancer and Fanconi anemia.
Author: Tischkowitz, Marc|Xia, Bing
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Journal: Nat Struct Mol Biol. 2010 Oct;17(10):1247-54.
Title: Cooperation of breast cancer proteins PALB2 and piccolo BRCA2 in stimulating homologous recombination.
Author: Buisson, Remi|Dion-Cote, Anne-Marie|Coulombe, Yan|Launay, Helene|Cai, Hong|Stasiak, Alicja Z|Stasiak, Andrzej|Xia, Bing|Masson, Jean-Yves
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Journal: Orv Hetil. 2010 Oct 31;151(44):1816-22.
Title: [The epidemiology of pancreatic cancer].
Author: Lakatos, Gabor|Tulassay, Zsolt
PMID: 20961843
Journal: Cancer Cell. 2010 Nov 16;18(5):499-509.
Title: Germline Brca2 heterozygosity promotes Kras(G12D) -driven carcinogenesis in a murine model of familial pancreatic cancer.
Author: Skoulidis, Ferdinandos|Cassidy, Liam D|Pisupati, Venkat|Jonasson, Jon G|Bjarnason, Hordur|Eyfjord, Jorunn E|Karreth, Florian A|Lim, Michael|Barber, Lorraine M|Clatworthy, Susan A|Davies, Susan E|Olive, Kenneth P|Tuveson, David A|Venkitaraman, Ashok R
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Journal: Breast Cancer Res Treat. 2011 Jun;127(2):357-62.
Title: PALB2 analysis in BRCA2-like families.
Author: Adank, M A|van Mil, S E|Gille, J J P|Waisfisz, Q|Meijers-Heijboer, H
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Journal: Mol Cancer Ther. 2011 Jan;10(1):3-8.
Title: Personalizing cancer treatment in the age of global genomic analyses: PALB2 gene mutations and the response to DNA damaging agents in pancreatic cancer.
Author: Villarroel, Maria C|Rajeshkumar, N V|Garrido-Laguna, Ignacio|De Jesus-Acosta, Ana|Jones, Sian|Maitra, Anirban|Hruban, Ralph H|Eshleman, James R|Klein, Alison|Laheru, Daniel|Donehower, Ross|Hidalgo, Manuel
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Journal: J Natl Cancer Inst. 2011 Feb 16;103(4):334-46.
Title: Therapeutic potential of poly(ADP-ribose) polymerase inhibitor AG014699 in human cancers with mutated or methylated BRCA1 or BRCA2.
Author: Drew, Yvette|Mulligan, Evan A|Vong, Wan-Tse|Thomas, Huw D|Kahn, Samra|Kyle, Suzanne|Mukhopadhyay, Asima|Los, Gerrit|Hostomsky, Zdenek|Plummer, Elizabeth R|Edmondson, Richard J|Curtin, Nicola J
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Journal: Gastroenterology. 2011 Apr;140(4):1303-1313.e1-3.
Title: Inactivation of Brca2 promotes Trp53-associated but inhibits KrasG12D-dependent pancreatic cancer development in mice.
Author: Rowley, Matthew|Ohashi, Akihiro|Mondal, Gourish|Mills, Lisa|Yang, Lin|Zhang, Lizhi|Sundsbak, Rhianna|Shapiro, Virginia|Muders, Michael H|Smyrk, Thomas|Couch, Fergus J
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Journal: Fam Cancer. 2011 Jun;10(2):323-30.
Title: German national case collection for familial pancreatic cancer (FaPaCa): ten years experience.
Author: Schneider, Ralph|Slater, Emily P|Sina, Mercede|Habbe, Nils|Fendrich, Volker|Matthai, Elvira|Langer, Peter|Bartsch, Detlef K
PMID: 21207249
Journal: Cancer Res. 2011 Mar 15;71(6):2222-9.
Title: Contribution of inherited mutations in the BRCA2-interacting protein PALB2 to familial breast cancer.
Author: Casadei, Silvia|Norquist, Barbara M|Walsh, Tom|Stray, Sunday|Mandell, Jessica B|Lee, Ming K|Stamatoyannopoulos, John A|King, Mary-Claire
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Journal: Mol Cancer Ther. 2011 Apr;10(4):670-8.
Title: Context dependence of checkpoint kinase 1 as a therapeutic target for pancreatic cancers deficient in the BRCA2 tumor suppressor.
Author: Hattori, Hiroyoshi|Skoulidis, Ferdinandos|Russell, Paul|Venkitaraman, Ashok R
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Journal: Gastroenterology. 2011 Apr;140(4):1143-6.
Title: Timing is everything: Brca2 and p53 mutations in pancreatic cancer.
Author: Morton, Jennifer P|Steele, Colin W|Sansom, Owen J
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Journal: Fam Cancer. 2011 Jun;10(2):225-31.
Title: PALB2 mutations in familial breast and pancreatic cancer.
Author: Hofstatter, Erin W|Domchek, Susan M|Miron, Alexander|Garber, Judy|Wang, Molin|Componeschi, Kathryn|Boghossian, Leigh|Miron, Penelope L|Nathanson, Katherine L|Tung, Nadine
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Journal: Cancer Biol Ther. 2011 Jun 1;11(11):959-68. Epub 2011 Jun 1.
Title: Inactivation of Brca2 cooperates with Trp53(R172H) to induce invasive pancreatic ductal adenocarcinomas in mice: a mouse model of familial pancreatic cancer.
Author: Feldmann, Georg|Karikari, Collins|dal Molin, Marco|Duringer, Stephanie|Volkmann, Petra|Bartsch, Detlef K|Bisht, Savita|Koorstra, Jan-Bart|Brossart, Peter|Maitra, Anirban|Fendrich, Volker
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Journal: Anticancer Res. 2011 Apr;31(4):1417-20.
Title: Evidence for the efficacy of Iniparib, a PARP-1 inhibitor, in BRCA2-associated pancreatic cancer.
Author: Fogelman, David R|Wolff, Robert A|Kopetz, Scott|Javle, Milind|Bradley, Charles|Mok, Isabel|Cabanillas, Fernando|Abbruzzese, James L
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Journal: Cancer Biol Ther. 2011 Jun 1;11(11):969-73. Epub 2011 Jun 1.
Title: Brca2 deficiency and Trp53 deregulation in pancreatic cancer: implications for therapeutic targeting.
Author: Yee, Nelson S
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Journal: Cancer Biol Ther. 2011 Aug 1;12(3):165-8. Epub 2011 Aug 1.
Title: Complete remission, in BRCA2 mutation carrier with metastatic pancreatic adenocarcinoma, treated with cisplatin based therapy.
Author: Sonnenblick, Amir|Kadouri, Luna|Appelbaum, Liat|Peretz, Tamar|Sagi, Michal|Goldberg, Yael|Hubert, Ayala
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Journal: PLoS One. 2011;6(7):e21639.
Title: Comprehensive genomic analysis of a BRCA2 deficient human pancreatic cancer.
Author: Barber, Louise J|Rosa Rosa, Juan M|Kozarewa, Iwanka|Fenwick, Kerry|Assiotis, Ioannis|Mitsopoulos, Costas|Sims, David|Hakas, Jarle|Zvelebil, Marketa|Lord, Christopher J|Ashworth, Alan
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Journal: Oncology. 2011;81(3-4):259-72.
Title: Molecular pathogenesis of pancreatic cancer and clinical perspectives.
Author: Matthaios, D|Zarogoulidis, P|Balgouranidou, I|Chatzaki, E|Kakolyris, S
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Journal: Cancer. 2012 Jan 15;118(2):493-9.
Title: Prevalence of BRCA1 and BRCA2 mutations in Ashkenazi Jewish families with breast and pancreatic cancer.
Author: Stadler, Zsofia K|Salo-Mullen, Erin|Patil, Sujata M|Pietanza, M Catherine|Vijai, Joseph|Saloustros, Emmanouil|Hansen, Nichole A L|Kauff, Noah D|Kurtz, Robert C|Kelsen, David P|Offit, Kenneth|Robson, Mark E
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Journal: Psychooncology. 2012 Dec;21(12):1324-30.
Title: Moderators of cancer-related distress and worry after a pancreatic cancer genetic counseling and screening intervention.
Author: Hart, Stacey L|Torbit, Lindsey A|Crangle, Cassandra J|Esplen, Mary Jane|Holter, Spring|Semotiuk, Kara|Borgida, Ayelet|Ardiles, Paola|Rothenmund, Heidi|Gallinger, Steve
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Journal: Dig Liver Dis. 2012 May;44(5):442-6.
Title: Familial intraductal papillary mucinous neoplasms of the pancreas.
Author: Rebours, Vinciane|Couvelard, Anne|Peyroux, Jean-Luc|Sauvanet, Alain|Hammel, Pascal|Ruszniewski, Philippe|Levy, Philippe
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Journal: Surgery. 2012 Jan;151(1):70-5.
Title: Intraductal papillary mucinous neoplasm of the pancreas: associated cancers, family history, genetic predisposition?
Author: Lubezky, Nir|Ben-Haim, Menahem|Lahat, Guy|Marmor, Sylvia|Solar, Irit|Brazowski, Eli|Nackache, Richard|Klausner, Joseph M
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Journal: Fam Cancer. 2012 Mar;11(1):41-7.
Title: Contribution of germline mutations in the BRCA and PALB2 genes to pancreatic cancer in Italy.
Author: Ghiorzo, P|Pensotti, V|Fornarini, G|Sciallero, S|Battistuzzi, L|Belli, F|Bonelli, L|Borgonovo, G|Bruno, W|Gozza, A|Gargiulo, S|Mastracci, L|Nasti, S|Palmieri, G|Papadia, F|Pastorino, L|Russo, A|Savarino, V|Varesco, L|Bernard, L|Bianchi Scarra, G
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Journal: Mol Carcinog. 2012 Jan;51(1):14-24.
Title: Genetic susceptibility to pancreatic cancer.
Author: Klein, Alison P
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Journal: Breast Cancer Res Treat. 2012 Apr;132(3):1119-26.
Title: The KL-VS sequence variant of Klotho and cancer risk in BRCA1 and BRCA2 mutation carriers.
Author: Laitman, Yael|Kuchenbaecker, Karoline B|Rantala, Johanna|Hogervorst, Frans|Peock, Susan|Godwin, Andrew K|Arason, Adalgeir|Kirchhoff, Tomas|Offit, Kenneth|Isaacs, Claudine|Schmutzler, Rita K|Wappenschmidt, Barbara|Nevanlinna, Heli|Chen, Xiaoqing|Chenevix-T
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Journal: Breast Cancer Res Treat. 2012 Jun;133(2):725-34.
Title: Molecular and clinical characterization of an in frame deletion of uncertain clinical significance in the BRCA2 gene.
Author: Rath, Michelle G|Fathali-Zadeh, Farnoosh|Langheinz, Anne|Tchatchou, Sandrine|Voigtlander, Theda|Heil, Jorg|Golatta, Michael|Schott, Sarah|Drasseck, Teresa|Behnecke, Anne|Burgemeister, Anna-Lena|Evers, Christina|Bugert, Peter|Junkermann, Hans|Schneeweiss,
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Journal: Mol Cell Biol. 2012 Apr;32(8):1506-17.
Title: PALB2 interacts with KEAP1 to promote NRF2 nuclear accumulation and function.
Author: Ma, Jianglin|Cai, Hong|Wu, Tongde|Sobhian, Bijan|Huo, Yanying|Alcivar, Allen|Mehta, Monal|Cheung, Ka Lung|Ganesan, Shridar|Kong, Ah-Ng Tony|Zhang, Donna D|Xia, Bing
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Journal: J Med Genet. 2012 Mar;49(3):164-70.
Title: CDKN2A is the main susceptibility gene in Italian pancreatic cancer families.
Author: Ghiorzo, Paola|Fornarini, Giuseppe|Sciallero, Stefania|Battistuzzi, Linda|Belli, Fiorenza|Bernard, Loris|Bonelli, Luigina|Borgonovo, Giacomo|Bruno, William|De Cian, Franco|Decensi, Andrea|Filauro, Marco|Faravelli, Francesca|Gozza, Alberto|Gargiulo, Sara|M
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Journal: Breast Cancer Res Treat. 2012 Jun;133(3):1153-7.
Title: Recurrent germline mutations in BRCA1 and BRCA2 genes in high risk families in Israel.
Author: Laitman, Yael|Simeonov, Monica|Herskovitz, Liron|Kushnir, Anya|Shimon-Paluch, Shani|Kaufman, Bella|Zidan, Jamal|Friedman, Eitan
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Journal: Bull Cancer. 2012 Apr 1;99(4):417-23.
Title: [What management for the asymptomatic men carriers of BRCA1 or 2 mutation? Results of a survey in the French oncogenetic centers].
Author: Brachot-Simeonova, Iglika|Morin, Gilles|Gillaux, Claire|Demeer, Benedicte|Gondry, Jean|Mathieu, Michele|Fauvet, Raffaele
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Journal: World J Gastroenterol. 2012 Mar 28;18(12):1286-94.
Title: Mouse models of pancreatic cancer.
Author: Herreros-Villanueva, Marta|Hijona, Elizabeth|Cosme, Angel|Bujanda, Luis
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Journal: Nat Rev Gastroenterol Hepatol. 2012 Aug;9(8):445-53.
Title: Familial pancreatic cancer--current knowledge.
Author: Bartsch, Detlef K|Gress, Thomas M|Langer, Peter
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Journal: Cancer J. 2012 Jul-Aug;18(4):350-4.
Title: Genetic testing by cancer site: pancreas.
Author: Axilbund, Jennifer E|Wiley, Elizabeth A
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Journal: Br J Cancer. 2012 Dec 4;107(12):2005-9.
Title: The incidence of pancreatic cancer in BRCA1 and BRCA2 mutation carriers.
Author: Iqbal, J|Ragone, A|Lubinski, J|Lynch, H T|Moller, P|Ghadirian, P|Foulkes, W D|Armel, S|Eisen, A|Neuhausen, S L|Senter, L|Singer, C F|Ainsworth, P|Kim-Sing, C|Tung, N|Friedman, E|Llacuachaqui, M|Ping, S|Narod, S A
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Journal: Cancer J. 2012 Nov-Dec;18(6):485-91.
Title: Inherited pancreatic cancer syndromes.
Author: Solomon, Sheila|Das, Siddhartha|Brand, Randall|Whitcomb, David C
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Journal: Coll Antropol. 2012 Sep;36(3):1063-7.
Title: Etiology and oncogenesis of pancreatic carcinoma.
Author: Dobrila-Dintinjana, Renata|Vanis, Nenad|Dintinjana, Marijan|Radic, Mladen
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Journal: Anticancer Agents Med Chem. 2013 Feb;13(2):261-9.
Title: BRCA2 dysfunction promotes malignant transformation of pancreatic intraepithelial neoplasia.
Author: Wang, Qi|Liu, Hongrui|Liu, Tingting|Shu, Shizhen|Jiang, He|Cheng, Shidan|Yuan, Yaozong|Yang, Weiguo|Wang, Lifu
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Journal: Gut. 2013 Mar;62(3):339-47.
Title: International Cancer of the Pancreas Screening (CAPS) Consortium summit on the management of patients with increased risk for familial pancreatic cancer.
Author: Canto, Marcia Irene|Harinck, Femme|Hruban, Ralph H|Offerhaus, George Johan|Poley, Jan-Werner|Kamel, Ihab|Nio, Yung|Schulick, Richard S|Bassi, Claudio|Kluijt, Irma|Levy, Michael J|Chak, Amitabh|Fockens, Paul|Goggins, Michael|Bruno, Marco
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Journal: Mol Oncol. 2013 Jun;7(3):308-22.
Title: Optimize radiochemotherapy in pancreatic cancer: PARP inhibitors a new therapeutic opportunity.
Author: Porcelli, Letizia|Quatrale, Anna E|Mantuano, Paola|Leo, Maria G|Silvestris, Nicola|Rolland, Jean F|Carioggia, Enza|Lioce, Marco|Paradiso, Angelo|Azzariti, Amalia
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Journal: Carcinogenesis. 2013 May;34(5):1001-5.
Title: Identification of common variants in BRCA2 and MAP2K4 for susceptibility to sporadic pancreatic cancer.
Author: Huang, Liming|Wu, Chen|Yu, Dianke|Wang, Chengfeng|Che, Xu|Miao, Xiaoping|Zhai, Kan|Chang, Jiang|Jiang, Guoliang|Yang, Xianghong|Cao, Guangwen|Hu, Zhibin|Zhou, Yongjian|Zuo, Chaohui|Wang, Chunyou|Zhang, Xianghong|Zhou, Yifeng|Yu, Xianjun|Dai, Wanjin|Li, Zh
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Journal: Cancer Epidemiol Biomarkers Prev. 2013 May;22(5):803-11.
Title: Risk of pancreatic cancer in breast cancer families from the breast cancer family registry.
Author: Mocci, Evelina|Milne, Roger L|Mendez-Villamil, Elena Yuste|Hopper, John L|John, Esther M|Andrulis, Irene L|Chung, Wendy K|Daly, Mary|Buys, Saundra S|Malats, Nuria|Goldgar, David E
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Journal: JOP. 2013 Mar 10;14(2):149-51.
Title: BRCA-associated pancreatic cancer: the evolving management.
Author: Leung, Keith|Saif, Muhammad Wasif
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Journal: Bioinformatics. 2013 Jun 15;29(12):1553-61.
Title: Systematic tracking of dysregulated modules identifies novel genes in cancer.
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Journal: Proc Natl Acad Sci U S A. 2013 May 21;110(21):8632-7.
Title: Palb2 synergizes with Trp53 to suppress mammary tumor formation in a model of inherited breast cancer.
Author: Bowman-Colin, Christian|Xia, Bing|Bunting, Samuel|Klijn, Christiaan|Drost, Rinske|Bouwman, Peter|Fineman, Laura|Chen, Xixi|Culhane, Aedin C|Cai, Hong|Rodig, Scott J|Bronson, Roderick T|Jonkers, Jos|Nussenzweig, Andre|Kanellopoulou, Chryssa|Livingston, Dav
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Journal: Clin Cancer Res. 2013 Jul 1;19(13):3396-403.
Title: High prevalence of BRCA1 and BRCA2 germline mutations with loss of heterozygosity in a series of resected pancreatic adenocarcinoma and other neoplastic lesions.
Author: Lucas, Aimee L|Shakya, Reena|Lipsyc, Marla D|Mitchel, Elana B|Kumar, Sheila|Hwang, Caroline|Deng, Liyong|Devoe, Catherine|Chabot, John A|Szabolcs, Matthias|Ludwig, Thomas|Chung, Wendy K|Frucht, Harold
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Journal: Mol Cancer Res. 2013 Aug;11(8):901-11.
Title: Mitoxantrone targets human ubiquitin-specific peptidase 11 (USP11) and is a potent inhibitor of pancreatic cancer cell survival.
Author: Burkhart, Richard A|Peng, Yu|Norris, Zoe A|Tholey, Renee M|Talbott, Vanessa A|Liang, Qin|Ai, Yongxing|Miller, Kathy|Lal, Shruti|Cozzitorto, Joseph A|Witkiewicz, Agnieska K|Yeo, Charles J|Gehrmann, Matthew|Napper, Andrew|Winter, Jordan M|Sawicki, Janet A|Z
PMID: 23696131
Journal: PLoS One. 2013 Jul 23;8(7):e67538.
Title: Analysis of PALB2 gene in BRCA1/BRCA2 negative Spanish hereditary breast/ovarian cancer families with pancreatic cancer cases.
Author: Blanco, Ana|de la Hoya, Miguel|Osorio, Ana|Diez, Orland|Miramar, Maria Dolores|Infante, Mar|Martinez-Bouzas, Cristina|Torres, Asuncion|Lasa, Adriana|Llort, Gemma|Brunet, Joan|Grana, Begona|Perez Segura, Pedro|Garcia, Maria Jose|Gutierrez-Enriquez, Sara|Ca
PMID: 23935836
Journal: Int J Colorectal Dis. 2014 Feb;29(2):139-45.
Title: Familial pancreatic cancer--status quo.
Author: Fendrich, Volker|Langer, Peter|Bartsch, Detlef K
PMID: 23948969
Journal: Clin Genet. 2014 Jan;85(1):18-20.
Title: Delineating the effects BRCA1 and BRCA2 loss of heterozygosity in pancreatic cancer progression.
Author: Fam, H K
PMID: 24147435
Journal: Mol Oncol. 2014 Mar;8(2):161-8.
Title: Chromosome instability and carcinogenesis: insights from murine models of human pancreatic cancer associated with BRCA2 inactivation.
Author: Cassidy, Liam D|Liau, Siong-Seng|Venkitaraman, Ashok R
PMID: 24268522
Journal: J Pathol. 2014 Mar;232(4):428-35.
Title: Whole-exome sequencing of pancreatic neoplasms with acinar differentiation.
Author: Jiao, Yuchen|Yonescu, Raluca|Offerhaus, G Johan A|Klimstra, David S|Maitra, Anirban|Eshleman, James R|Herman, James G|Poh, Weijie|Pelosof, Lorraine|Wolfgang, Christopher L|Vogelstein, Bert|Kinzler, Kenneth W|Hruban, Ralph H|Papadopoulos, Nickolas|Wood, La
PMID: 24293293
Journal: Genes Dev. 2014 Jan 1;28(1):1-7.
Title: Familial pancreatic cancer: genetic advances.
Author: Rustgi, Anil K
PMID: 24395243
Journal: Cancer. 2014 May 15;120(10):1557-64.
Title: Characteristics of individuals with breast cancer rearrangements in BRCA1 and BRCA2.
Author: Jackson, Sarah A|Davis, Andrew A|Li, Jun|Yi, Nengjun|McCormick, Shelley R|Grant, Carly|Fallen, Taya|Crawford, Beth|Loranger, Kate|Litton, Jennifer|Arun, Banu|Vande Wydeven, Kimberly|Sidani, Amer|Farmer, Katie|Sanders, Merideth|Hoskins, Kent|Nussbaum, Robe
PMID: 24522996
Journal: Tumour Biol. 2014 Jun;35(6):5061-6.
Title: The function of EMSY in cancer development.
Author: Hou, Jing|Wang, Ziliang|Yang, Lina|Guo, Xiaomao|Yang, Gong
PMID: 24609898
Journal: Pancreas. 2014 Apr;43(3):458-61.
Title: Promising outcomes of screening for pancreatic cancer by genetic testing and endoscopic ultrasound.
Author: Sud, Anchal|Wham, Deborah|Catalano, Marc|Guda, Nalini M
PMID: 24622079
Journal: Semin Radiat Oncol. 2014 Apr;24(2):67-76.
Title: The clinical utility of biomarkers in the management of pancreatic adenocarcinoma.
Author: Jazieh, Khalid A|Foote, Michael B|Diaz, Luis A Jr
PMID: 24635863
Journal: Cancer. 2014 Jul 1;120(13):1960-7.
Title: BRCA1 and BRCA2 germline mutations are frequently demonstrated in both high-risk pancreatic cancer screening and pancreatic cancer cohorts.
Author: Lucas, Aimee L|Frado, Laura E|Hwang, Caroline|Kumar, Sheila|Khanna, Lauren G|Levinson, Elana J|Chabot, John A|Chung, Wendy K|Frucht, Harold
PMID: 24737347
Journal: J Gastrointest Cancer. 2014 Sep;45(3):256-61.
Title: Familial pancreatic cancer: challenging diagnostic approach and therapeutic management.
Author: Mastoraki, Aikaterini|Chatzimavridou-Grigoriadou, Victoria|Chatzipetrou, Varvara|Mastoraki, Sotiria|Papanikolaou, Ioannis S|Danias, Nikolaos|Smyrniotis, Vasilios|Arkadopoulos, Nikolaos
PMID: 24756831
Journal: Mol Cancer. 2014 Apr 28;13:94.
Title: The negative interplay between Aurora A/B and BRCA1/2 controls cancer cell growth and tumorigenesis via distinct regulation of cell cycle progression, cytokinesis, and tetraploidy.
Author: Wang, Yan|Wang, Ziliang|Qi, Zihao|Yin, Sheng|Zhang, Na|Liu, Yang|Liu, Mingming|Meng, Jiao|Zang, Rongyu|Zhang, Zhen|Yang, Gong
PMID: 24775809
Journal: Biochem J. 2014 Jun 15;460(3):331-42.
Title: Exploring the roles of PALB2 at the crossroads of DNA repair and cancer.
Author: Pauty, Joris|Rodrigue, Amelie|Couturier, Anthony|Buisson, Remi|Masson, Jean-Yves
PMID: 24870022
Journal: Case Rep Oncol Med. 2014;2014:860532.
Title: Squamous Cell Carcinoma of the Pancreas in a Patient with Germline BRCA2 Mutation-Response to Neoadjuvant Radiochemotherapy.
Author: Schultheis, Anne M|Nguyen, Gia Phuong|Ortmann, Monika|Kruis, Wolfgang|Buttner, Reinhard|Schildhaus, Hans-Ulrich|Markiefka, Birgid
PMID: 24959366
Journal: Bull Cancer. 2014 Sep;101(9):813-22.
Title: [Hereditary predisposition to cancers of the digestive tract, breast, gynecological and gonadal: focus on the Peutz-Jeghers].
Author: Turpin, Anthony|Cattan, Stephane|Leclerc, Julie|Wacrenier, Agnes|Manouvrier-Hanu, Sylvie|Buisine, Marie-Pierre|Lejeune-Dumoulin, Sophie
PMID: 25036236
Journal: Br J Cancer. 2014 Sep 9;111(6):1132-8.
Title: Overall survival and clinical characteristics of pancreatic cancer in BRCA mutation carriers.
Author: Golan, T|Kanji, Z S|Epelbaum, R|Devaud, N|Dagan, E|Holter, S|Aderka, D|Paluch-Shimon, S|Kaufman, B|Gershoni-Baruch, R|Hedley, D|Moore, M J|Friedman, E|Gallinger, S
PMID: 25072261
Journal: JOP. 2014 Jul 28;15(4):340-3.
Title: PARP-inhibitors in BRCA-associated pancreatic cancer.
Author: Bhalla, Anshul|Saif, Muhammad Wasif
PMID: 25076338
Journal: Cancer. 2015 Jan 15;121(2):269-75.
Title: Cancers associated with BRCA1 and BRCA2 mutations other than breast and ovarian.
Author: Mersch, Jacqueline|Jackson, Michelle A|Park, Minjeong|Nebgen, Denise|Peterson, Susan K|Singletary, Claire|Arun, Banu K|Litton, Jennifer K
PMID: 25224030
Journal: Genet Med. 2015 Jul;17(7):569-77.
Title: BRCA1, BRCA2, PALB2, and CDKN2A mutations in familial pancreatic cancer: a PACGENE study.
Author: Zhen, David B|Rabe, Kari G|Gallinger, Steven|Syngal, Sapna|Schwartz, Ann G|Goggins, Michael G|Hruban, Ralph H|Cote, Michele L|McWilliams, Robert R|Roberts, Nicholas J|Cannon-Albright, Lisa A|Li, Donghui|Moyes, Kelsey|Wenstrup, Richard J|Hartman, Anne-Rene
PMID: 25356972
Journal: J Clin Oncol. 2015 Jan 20;33(3):244-50.
Title: Olaparib monotherapy in patients with advanced cancer and a germline BRCA1/2 mutation.
Author: Kaufman, Bella|Shapira-Frommer, Ronnie|Schmutzler, Rita K|Audeh, M William|Friedlander, Michael|Balmana, Judith|Mitchell, Gillian|Fried, Georgeta|Stemmer, Salomon M|Hubert, Ayala|Rosengarten, Ora|Steiner, Mariana|Loman, Niklas|Bowen, Karin|Fielding, Anitr
PMID: 25366685
Journal: Gastroenterology. 2015 Mar;148(3):556-64.
Title: Prevalence of germline mutations in cancer predisposition genes in patients with pancreatic cancer.
Author: Grant, Robert C|Selander, Iris|Connor, Ashton A|Selvarajah, Shamini|Borgida, Ayelet|Briollais, Laurent|Petersen, Gloria M|Lerner-Ellis, Jordan|Holter, Spring|Gallinger, Steven
PMID: 25479140
Journal: Fam Cancer. 2015 Sep;14(3):341-8.
Title: Analysis of PALB2 in a cohort of Italian breast cancer patients: identification of a novel PALB2 truncating mutation.
Author: Vietri, Maria Teresa|Caliendo, Gemma|Schiano, Concetta|Casamassimi, Amelia|Molinari, Anna Maria|Napoli, Claudio|Cioffi, Michele
PMID: 25666743
Journal: Nature. 2015 Feb 26;518(7540):495-501.
Title: Whole genomes redefine the mutational landscape of pancreatic cancer.
Author: Waddell, Nicola|Pajic, Marina|Patch, Ann-Marie|Chang, David K|Kassahn, Karin S|Bailey, Peter|Johns, Amber L|Miller, David|Nones, Katia|Quek, Kelly|Quinn, Michael C J|Robertson, Alan J|Fadlullah, Muhammad Z H|Bruxner, Tim J C|Christ, Angelika N|Harliwong,
PMID: 25719666
Journal: Breast Cancer Res Treat. 2015 Apr;150(3):631-5.
Title: Cancer risks in Jewish male BRCA1 and BRCA2 mutation carriers.
Author: Laitman, Yael|Keinan Boker, Lital|Liphsitz, Irena|Weissglas-Volkov, Daphna|Litz-Philipsborn, Shira|Schayek, Hagit|Friedman, Eitan
PMID: 25788227
Journal: JAMA Surg. 2015 Jun;150(6):512-8.
Title: Short-term Results of a Magnetic Resonance Imaging-Based Swedish Screening Program for Individuals at Risk for Pancreatic Cancer.
Author: Del Chiaro, Marco|Verbeke, Caroline S|Kartalis, Nikolaos|Pozzi Mucelli, Raffaella|Gustafsson, Peter|Hansson, Johan|Haas, Stephan L|Segersvard, Ralf|Andren-Sandberg, Ake|Lohr, J-Matthias
PMID: 25853369
Journal: Cancer Lett. 2015 Aug 1;364(1):8-16.
Title: Increased in vitro and in vivo sensitivity of BRCA2-associated pancreatic cancer to the poly(ADP-ribose) polymerase-1/2 inhibitor BMN 673.
Author: Andrei, Alexandra-Zoe|Hall, Anita|Smith, Alyssa L|Bascunana, Claire|Malina, Abba|Connor, Ashton|Altinel-Omeroglu, Gulbeyaz|Huang, Sidong|Pelletier, Jerry|Huntsman, David|Gallinger, Steven|Omeroglu, Atilla|Metrakos, Peter|Zogopoulos, George
PMID: 25864590
Journal: Oncotarget. 2015 May 10;6(13):11575-84.
Title: Autoimmune response to PARP and BRCA1/BRCA2 in cancer.
Author: Zhu, Qing|Han, Su-Xia|Zhou, Cong-Ya|Cai, Meng-Jiao|Dai, Li-Ping|Zhang, Jian-Ying
PMID: 25865228
Journal: Clin Cancer Res. 2015 May 1;21(9):2029-37.
Title: Precision Medicine for Advanced Pancreas Cancer: The Individualized Molecular Pancreatic Cancer Therapy (IMPaCT) Trial.
Author: Chantrill, Lorraine A|Nagrial, Adnan M|Watson, Clare|Johns, Amber L|Martyn-Smith, Mona|Simpson, Skye|Mead, Scott|Jones, Marc D|Samra, Jaswinder S|Gill, Anthony J|Watson, Nicole|Chin, Venessa T|Humphris, Jeremy L|Chou, Angela|Brown, Belinda|Morey, Adrienne
PMID: 25896973
Journal: Oncologist. 2015 Jun;20(6):593-7.
Title: BRCAPRO 6.0 Model Validation in Male Patients Presenting for BRCA Testing.
Author: Mitri, Zahi I|Jackson, Michelle|Garby, Carolyn|Song, Juhee|Giordano, Sharon H|Hortobagyi, Gabriel N|Singletary, Claire N|Hashmi, S Shahrukh|Arun, Banu K|Litton, Jennifer K
PMID: 25948675
Journal: J Clin Oncol. 2015 Oct 1;33(28):3080-1.
Title: Assessing the Significance of BRCA1 and BRCA2 Mutations in Pancreatic Cancer.
Author: Carnevale, Julia|Ashworth, Alan
PMID: 25987697
Journal: Cancer. 2015 Sep 1;121(17):3047.
Title: Reply to BRCA2-associated pancreatic cancer and current screening guidelines.
Author: Litton, Jennifer K|Lee, Jeffrey H|Arun, Banu K
PMID: 26018033
Journal: Cancer. 2015 Sep 1;121(17):3046.
Title: BRCA2-associated pancreatic cancer and current screening guidelines.
Author: Kasi, Pashtoon Murtaza|Pedersen, Katrina S|McWilliams, Robert R
PMID: 26018189
Journal: Sultan Qaboos Univ Med J. 2015 May;15(2):e218-25. Epub 2015 May 28.
Title: Predicting the Pathogenic Potential of BRCA1 and BRCA2 Gene Variants Identified in Clinical Genetic Testing.
Author: Brookes, Clare|Lai, Stella|Doherty, Elaine|Love, Donald R
PMID: 26052455
Journal: Nat Genet. 2015 Aug;47(8):911-6.
Title: Common variation at 2p13.3, 3q29, 7p13 and 17q25.1 associated with susceptibility to pancreatic cancer.
Author: Childs, Erica J|Mocci, Evelina|Campa, Daniele|Bracci, Paige M|Gallinger, Steven|Goggins, Michael|Li, Donghui|Neale, Rachel E|Olson, Sara H|Scelo, Ghislaine|Amundadottir, Laufey T|Bamlet, William R|Bijlsma, Maarten F|Blackford, Amanda|Borges, Michael|Brenn
PMID: 26098869
Journal: Br J Cancer. 2015 Jul 28;113(3):425-32.
Title: BRCA1 and BRCA2 mutations sensitize to chemotherapy in patient-derived pancreatic cancer xenografts.
Author: Lohse, I|Borgida, A|Cao, P|Cheung, M|Pintilie, M|Bianco, T|Holter, S|Ibrahimov, E|Kumareswaran, R|Bristow, R G|Tsao, M-S|Gallinger, S|Hedley, D W
PMID: 26180923
Journal: Eur J Cancer. 2015 Sep;51(14):1911-7.
Title: PanGen-Fam: Spanish registry of hereditary pancreatic cancer.
Author: Mocci, E|Guillen-Ponce, C|Earl, J|Marquez, M|Solera, J|Salazar-Lopez, M-T|Calcedo-Arnaiz, C|Vazquez-Sequeiros, E|Montans, J|Munoz-Beltran, M|Vicente-Bartulos, A|Gonzalez-Gordaliza, C|Sanjuanbenito, A|Guerrero, C|Mendia, E|Lisa, E|Lobo, E|Martinez, J C|Rea
PMID: 26212471
Journal: Hematol Oncol Clin North Am. 2015 Aug;29(4):641-53.
Title: Familial Pancreatic Adenocarcinoma.
Author: Petersen, Gloria M
PMID: 26226902
Journal: World J Gastrointest Endosc. 2015 Jul 25;7(9):833-42.
Title: Methods and outcomes of screening for pancreatic adenocarcinoma in high-risk individuals.
Author: Capurso, Gabriele|Signoretti, Marianna|Valente, Roberto|Arnelo, Urban|Lohr, Matthias|Poley, Jan-Werner|Delle Fave, Gianfranco|Del Chiaro, Marco
PMID: 26240684
Journal: Eur J Med Chem. 2015 Sep 18;102:530-9.
Title: Quinazolinedione SIRT6 inhibitors sensitize cancer cells to chemotherapeutics.
Author: Sociali, Giovanna|Galeno, Lauretta|Parenti, Marco Daniele|Grozio, Alessia|Bauer, Inga|Passalacqua, Mario|Boero, Silvia|Donadini, Alessandra|Millo, Enrico|Bellotti, Marta|Sturla, Laura|Damonte, Patrizia|Puddu, Alessandra|Ferroni, Claudia|Varchi, Greta|Fran
PMID: 26310895
Journal: Cancer. 2015 Dec 15;121(24):4382-8.
Title: Identification of germline genetic mutations in patients with pancreatic cancer.
Author: Salo-Mullen, Erin E|O'Reilly, Eileen M|Kelsen, David P|Ashraf, Asad M|Lowery, Maeve A|Yu, Kenneth H|Reidy, Diane L|Epstein, Andrew S|Lincoln, Anne|Saldia, Amethyst|Jacobs, Lauren M|Rau-Murthy, Rohini|Zhang, Liying|Kurtz, Robert C|Saltz, Leonard|Offit, Ken
PMID: 26440929
Journal: Nat Commun. 2015 Oct 29;6:8683.
Title: A mutational signature in gastric cancer suggests therapeutic strategies.
Author: Alexandrov, Ludmil B|Nik-Zainal, Serena|Siu, Hoi Cheong|Leung, Suet Yi|Stratton, Michael R
PMID: 26511885
Journal: Neoplasia. 2015 Oct;17(10):757-66.
Title: Sensitization of Pancreatic Cancers to Gemcitabine Chemoradiation by WEE1 Kinase Inhibition Depends on Homologous Recombination Repair.
Author: Kausar, Tasneem|Schreiber, Jason S|Karnak, David|Parsels, Leslie A|Parsels, Joshua D|Davis, Mary A|Zhao, Lili|Maybaum, Jonathan|Lawrence, Theodore S|Morgan, Meredith A
PMID: 26585231
Journal: Melanoma Manag. 2015 Feb;2(1):83-89.
Title: Familial risk of melanoma and links with other cancers.
Author: Lee, Kachiu C|Higgins, H William 2nd|Qureshi, Abrar A
PMID: 30190834
Journal: Int J Clin Oncol. 2016 Apr;21(2):270-275.
Title: Analysis of PALB2 mutations in 155 Japanese patients with breast and/or ovarian cancer.
Author: Nakagomi, Hiroshi|Sakamoto, Ikuko|Hirotsu, Yosuke|Amemiya, Kenji|Mochiduki, Hitoshi|Omata, Masao
PMID: 26411315
Journal: Expert Opin Ther Targets. 2016;20(3):341-59.
Title: Molecular signature of pancreatic adenocarcinoma: an insight from genotype to phenotype and challenges for targeted therapy.
Author: Sahin, Ibrahim H|Iacobuzio-Donahue, Christine A|O'Reilly, Eileen M
PMID: 26439702
Journal: Cancer Epidemiol Biomarkers Prev. 2016 Jan;25(1):207-11.
Title: Prevalence of Pathogenic Mutations in Cancer Predisposition Genes among Pancreatic Cancer Patients.
Author: Hu, Chunling|Hart, Steven N|Bamlet, William R|Moore, Raymond M|Nandakumar, Kannabiran|Eckloff, Bruce W|Lee, Yean K|Petersen, Gloria M|McWilliams, Robert R|Couch, Fergus J
PMID: 26483394
Journal: Cancer. 2016 Jan 15;122(2):304-11.
Title: Inherited mutations in cancer susceptibility genes are common among survivors of breast cancer who develop therapy-related leukemia.
Author: Churpek, Jane E|Marquez, Rafael|Neistadt, Barbara|Claussen, Kimberly|Lee, Ming K|Churpek, Matthew M|Huo, Dezheng|Weiner, Howard|Bannerjee, Mekhala|Godley, Lucy A|Le Beau, Michelle M|Pritchard, Colin C|Walsh, Tom|King, Mary-Claire|Olopade, Olufunmilayo I|L
PMID: 26641009
Journal: Cancer Discov. 2016 Feb;6(2):166-75.
Title: Whole Genome Sequencing Defines the Genetic Heterogeneity of Familial Pancreatic Cancer.
Author: Roberts, Nicholas J|Norris, Alexis L|Petersen, Gloria M|Bondy, Melissa L|Brand, Randall|Gallinger, Steven|Kurtz, Robert C|Olson, Sara H|Rustgi, Anil K|Schwartz, Ann G|Stoffel, Elena|Syngal, Sapna|Zogopoulos, George|Ali, Syed Z|Axilbund, Jennifer|Chaffee,
PMID: 26658419
Journal: Klin Onkol. 2016;29 Suppl 1:S9-13.
Title: [Recommended Extension of Indication Criteria for Genetic Testing of BRCA1 and BRCA2 Mutations in Hereditary Breast and Ovarian Cancer Syndrome].
Author: Foretova, L|Machackova, E|Palacova, M|Navratilova, M|Svoboda, M|Petrakova, K
PMID: 26691937
Journal: Klin Onkol. 2016;29 Suppl 1:S14-21.
Title: [Hereditary Breast and Ovarian Cancer Syndrome].
Author: Petrakova, K|Palacova, M|Schneiderova, M|Standara, M
PMID: 26691938
Journal: Klin Onkol. 2016;29 Suppl 1:S31-4.
Title: [PALB2 as Another Candidate Gene for Genetic Testing in Patients with Hereditary Breast Cancer in Czech Republic].
Author: Janatova, M|Borecka, M|Soukupova, J|Kleiblova, P|Stribrna, J|Vocka, M|Zemankova, P|Panczak, A|Vesela, K|Soucek, P|Foretova, L|Kleibl, Z
PMID: 26691940
Journal: Med Oncol. 2016 Jan;33(1):4.
Title: Biweekly gemcitabine and low-dose cisplatin in the treatment of locally advanced or metastatic pancreatic cancer patients: a single institute experience.
Author: Lundberg, Jordan|Reardon, Joshua|Blazer, Marlo|Phillips, Gary|Bekaii-Saab, Tanios
PMID: 26696390
Journal: Ann Surg Oncol. 2016 May;23(5):1729-35.
Title: Statewide Retrospective Review of Familial Pancreatic Cancer in Delaware, and Frequency of Genetic Mutations in Pancreatic Cancer Kindreds.
Author: Catts, Zohra Ali-Khan|Baig, Muhammad Khurram|Milewski, Becky|Keywan, Christine|Guarino, Michael|Petrelli, Nicholas
PMID: 26727920
Journal: Nat Commun. 2016 Feb 26;7:10770.
Title: Multiplexed pancreatic genome engineering and cancer induction by transfection-based CRISPR/Cas9 delivery in mice.
Author: Maresch, Roman|Mueller, Sebastian|Veltkamp, Christian|Ollinger, Rupert|Friedrich, Mathias|Heid, Irina|Steiger, Katja|Weber, Julia|Engleitner, Thomas|Barenboim, Maxim|Klein, Sabine|Louzada, Sandra|Banerjee, Ruby|Strong, Alexander|Stauber, Teresa|Gross, Nin
PMID: 26916719
Journal: Scientifica (Cairo). 2016;2016:5619358.
Title: Frequency and Significance of Abnormal Pancreatic Imaging in Patients with BRCA1 and BRCA2 Genetic Mutations.
Author: Chahla, Elie|Cheesman, Antonio|Mahon, Suzanne M|Garrett, Robert W|Bradenham, Ben P Jr|Schwartz, Theresa L|Omran, Louay|Taylor, Jason R|Alkaade, Samer
PMID: 27069714
Journal: Cancer Genet. 2016 May;209(5):199-204.
Title: Mutation analysis of the PALB2 gene in unselected pancreatic cancer patients in the Czech Republic.
Author: Borecka, M|Zemankova, P|Vocka, M|Soucek, P|Soukupova, J|Kleiblova, P|Sevcik, J|Kleibl, Z|Janatova, M
PMID: 27106063
Journal: J Clin Oncol. 2016 Jun 10;34(17):2010-9.
Title: Benefit of Surveillance for Pancreatic Cancer in High-Risk Individuals: Outcome of Long-Term Prospective Follow-Up Studies From Three European Expert Centers.
Author: Vasen, Hans|Ibrahim, Isaura|Ponce, Carmen Guillen|Slater, Emily P|Matthai, Elvira|Carrato, Alfredo|Earl, Julie|Robbers, Kristin|van Mil, Anneke M|Potjer, Thomas|Bonsing, Bert A|de Vos Tot Nederveen Cappel, Wouter H|Bergman, Wilma|Wasser, Martin|Morreau, H
PMID: 27114589
Journal: J Transl Med. 2016 May 10;14(1):129.
Title: Novel patient-derived xenograft mouse model for pancreatic acinar cell carcinoma demonstrates single agent activity of oxaliplatin.
Author: Hall, Jason C|Marlow, Laura A|Mathias, Adam C|Dawson, Louis K|Durham, William F|Meshaw, Kenneth A|Mullin, Robert J|Synnott, Aidan J|Small, Daniel L|Krishna, Murli|von Hoff, Daniel|Schuler, Julia|Hart, Steven N|Couch, Fergus J|Colon-Otero, Gerardo|Copland,
PMID: 27165126
Journal: Cancer Epidemiol Biomarkers Prev. 2016 Jul;25(7):1185-91.
Title: Association of Common Susceptibility Variants of Pancreatic Cancer in Higher-Risk Patients: A PACGENE Study.
Author: Childs, Erica J|Chaffee, Kari G|Gallinger, Steven|Syngal, Sapna|Schwartz, Ann G|Cote, Michele L|Bondy, Melissa L|Hruban, Ralph H|Chanock, Stephen J|Hoover, Robert N|Fuchs, Charles S|Rider, David N|Amundadottir, Laufey T|Stolzenberg-Solomon, Rachael|Wolpin
PMID: 27197284
Journal: Oncologist. 2016 Jul;21(7):869-74.
Title: Cancer Incidence in First- and Second-Degree Relatives of BRCA1 and BRCA2 Mutation Carriers.
Author: Streff, Haley|Profato, Jessica|Ye, Yuanqing|Nebgen, Denise|Peterson, Susan K|Singletary, Claire|Arun, Banu K|Litton, Jennifer K
PMID: 27306910
Journal: Climacteric. 2016 Oct;19(5):419-22.
Title: Hormone therapy after prophylactic risk-reducing bilateral salpingo-oophorectomy in women who have BRCA gene mutation.
Author: Guidozzi, F
PMID: 27426853
Journal: Endocr Relat Cancer. 2016 Oct;23(10):T1-T17.
Title: BRCA2 functions: from DNA repair to replication fork stabilization.
Author: Fradet-Turcotte, Amelie|Sitz, Justine|Grapton, Damien|Orthwein, Alexandre
PMID: 27530658
Journal: PLoS One. 2016 Aug 17;11(8):e0161438.
Title: Analysis of Founder Mutations in Rare Tumors Associated With Hereditary Breast/Ovarian Cancer Reveals a Novel Association of BRCA2 Mutations with Ampulla of Vater Carcinomas.
Author: Pinto, Pedro|Peixoto, Ana|Santos, Catarina|Rocha, Patricia|Pinto, Carla|Pinheiro, Manuela|Leca, Luis|Martins, Ana Teresa|Ferreira, Veronica|Bartosch, Carla|Teixeira, Manuel R
PMID: 27532258
Journal: Medicine (Baltimore). 2016 Sep;95(36):e4756.
Title: First case report of an adrenocortical carcinoma caused by a BRCA2 mutation.
Author: El Ghorayeb, Nada|Grunenwald, Solange|Nolet, Serge|Primeau, Vanessa|Cote, Stephanie|Maugard, Christine M|Lacroix, Andre|Gaboury, Louis|Bourdeau, Isabelle
PMID: 27603373
Journal: Sci Rep. 2016 Sep 12;6:33323.
Title: WEE1 inhibition in pancreatic cancer cells is dependent on DNA repair status in a context dependent manner.
Author: Lal, Shruti|Zarei, Mahsa|Chand, Saswati N|Dylgjeri, Emanuela|Mambelli-Lisboa, Nicole C|Pishvaian, Michael J|Yeo, Charles J|Winter, Jordan M|Brody, Jonathan R
PMID: 27616351
Journal: Biomed Res Int. 2016;2016:4873089.
Title: Can Molecular Biomarkers Change the Paradigm of Pancreatic Cancer Prognosis?
Author: Martinez-Useros, Javier|Garcia-Foncillas, Jesus
PMID: 27689078
Journal: Case Rep Oncol. 2016 Jul 21;9(2):387-394.
Title: Synchronous Onset of Breast and Pancreatic Cancers: Results of Germline and Somatic Genetic Analysis.
Author: Castro, Michael|Vierkoetter, Koah|Prager, Douglas|Montgomery, Shasta|Sedgwick, Kristin
PMID: 27721756
Journal: Oncology (Williston Park). 2016 Oct 15;30(10):896-904.
Title: Prevention and Screening in Hereditary Breast and Ovarian Cancer.
Author: Zeichner, Simon B|Stanislaw, Christine|Meisel, Jane L
PMID: 27753056
Journal: PLoS One. 2016 Dec 29;11(12):e0167272.
Title: Effects of Combined Treatment with Ionizing Radiation and the PARP Inhibitor Olaparib in BRCA Mutant and Wild Type Patient-Derived Pancreatic Cancer Xenografts.
Author: Lohse, Ines|Kumareswaran, Ramya|Cao, Pinjiang|Pitcher, Bethany|Gallinger, Steven|Bristow, Robert G|Hedley, David W
PMID: 28033382
Journal: Biomed Res Int. 2016;2016:1869304.
Title: The Role of BRCA2 Mutation Status as Diagnostic, Predictive, and Prognosis Biomarker for Pancreatic Cancer.
Author: Martinez-Useros, Javier|Garcia-Foncillas, Jesus
PMID: 28078281
Journal: Fam Cancer. 2017 Apr;16(2):303-309.
Title: Double germline mutations in APC and BRCA2 in an individual with a pancreatic tumor.
Author: Goehringer, Caroline|Sutter, Christian|Kloor, Matthias|Gebert, Johannes|Slater, Emily P|Keller, Monika|Treiber, Irmgard|Ganschow, Petra|Kadmon, Martina|Moog, Ute
PMID: 27838800
Journal: Am J Clin Pathol. 2017 Jan 1;147(1):110-119.
Title: Male Breast Cancer.
Author: Serdy, Kate M|Leone, Jose Pablo|Dabbs, David J|Bhargava, Rohit
PMID: 28171879
Journal: Br J Cancer. 2017 Mar 14;116(6):697-702.
Title: Overall survival and clinical characteristics of BRCA mutation carriers with stage I/II pancreatic cancer.
Author: Golan, Talia|Sella, Tal|O'Reilly, Eileen M|Katz, Matthew H G|Epelbaum, Ron|Kelsen, David P|Borgida, Ayelet|Maynard, Hannah|Kindler, Hedy|Friedmen, Eitan|Javle, Milind|Gallinger, Steven
PMID: 28183138
Journal: Nat Med. 2017 Apr;23(4):517-525.
Title: HRDetect is a predictor of BRCA1 and BRCA2 deficiency based on mutational signatures.
Author: Davies, Helen|Glodzik, Dominik|Morganella, Sandro|Yates, Lucy R|Staaf, Johan|Zou, Xueqing|Ramakrishna, Manasa|Martin, Sancha|Boyault, Sandrine|Sieuwerts, Anieta M|Simpson, Peter T|King, Tari A|Raine, Keiran|Eyfjord, Jorunn E|Kong, Gu|Borg, Ake|Birney, Ewa
PMID: 28288110
Journal: Br J Cancer. 2017 Apr 11;116(8):1021-1026.
Title: BRCA2 secondary mutation-mediated resistance to platinum and PARP inhibitor-based therapy in pancreatic cancer.
Author: Pishvaian, Michael J|Biankin, Andrew V|Bailey, Peter|Chang, David K|Laheru, Daniel|Wolfgang, Christopher L|Brody, Jonathan R
PMID: 28291774
Journal: Oncotarget. 2017 May 30;8(22):36033-36039.
Title: BRCA1 missense polymorphisms are associated with poor prognosis of pancreatic cancer patients in a Chinese population.
Author: Zhu, Ying|Zhai, Kan|Ke, Juntao|Li, Jiaoyuan|Gong, Yajie|Yang, Yang|Tian, Jianbo|Zhang, Yi|Zou, Danyi|Peng, Xiating|Gong, Jing|Zhong, Rong|Huang, Kun|Chang, Jiang|Miao, Xiaoping
PMID: 28415599
Journal: Oncotarget. 2017 Jul 4;8(27):44073-44081.
Title: Olaparib in combination with irinotecan, cisplatin, and mitomycin C in patients with advanced pancreatic cancer.
Author: Yarchoan, Mark|Myzak, Melinda C|Johnson, Burles A 3rd|De Jesus-Acosta, Ana|Le, Dung T|Jaffee, Elizabeth M|Azad, Nilofer S|Donehower, Ross C|Zheng, Lei|Oberstein, Paul E|Fine, Robert L|Laheru, Daniel A|Goggins, Michael
PMID: 28454122
Journal: Cancer Res. 2017 Jul 15;77(14):3857-3869.
Title: Nicotinic Acid Phosphoribosyltransferase Regulates Cancer Cell Metabolism, Susceptibility to NAMPT Inhibitors, and DNA Repair.
Author: Piacente, Francesco|Caffa, Irene|Ravera, Silvia|Sociali, Giovanna|Passalacqua, Mario|Vellone, Valerio G|Becherini, Pamela|Reverberi, Daniele|Monacelli, Fiammetta|Ballestrero, Alberto|Odetti, Patrizio|Cagnetta, Antonia|Cea, Michele|Nahimana, Aimable|Duchos
PMID: 28507103
Journal: Oncotarget. 2017 Jun 20;8(25):39945-39962.
Title: BRCA2, EGFR, and NTRK mutations in mismatch repair-deficient colorectal cancers with MSH2 or MLH1 mutations.
Author: Deihimi, Safoora|Lev, Avital|Slifker, Michael|Shagisultanova, Elena|Xu, Qifang|Jung, Kyungsuk|Vijayvergia, Namrata|Ross, Eric A|Xiu, Joanne|Swensen, Jeffrey|Gatalica, Zoran|Andrake, Mark|Dunbrack, Roland L|El-Deiry, Wafik S
PMID: 28591715
Journal: Proc Natl Acad Sci U S A. 2017 Jul 3;114(27):7106-7111.
Title: Targeting reactive nitrogen species suppresses hereditary pancreatic cancer.
Author: Li, Mo|Chen, Qian|Ma, Teng|Yu, Xiaochun
PMID: 28630313
Journal: Cancer Epidemiol Biomarkers Prev. 2017 Oct;26(10):1540-1548.
Title: Impact of Sixteen Established Pancreatic Cancer Susceptibility Loci in American Jews.
Author: Streicher, Samantha A|Klein, Alison P|Olson, Sara H|Amundadottir, Laufey T|DeWan, Andrew T|Zhao, Hongyu|Risch, Harvey A
PMID: 28754795
Journal: J Clin Oncol. 2017 Oct 20;35(30):3382-3390.
Title: Deleterious Germline Mutations in Patients With Apparently Sporadic Pancreatic Adenocarcinoma.
Author: Shindo, Koji|Yu, Jun|Suenaga, Masaya|Fesharakizadeh, Shahriar|Cho, Christy|Macgregor-Das, Anne|Siddiqui, Abdulrehman|Witmer, P Dane|Tamura, Koji|Song, Tae Jun|Navarro Almario, Jose Alejandro|Brant, Aaron|Borges, Michael|Ford, Madeline|Barkley, Thomas|He,
PMID: 28767289
Journal: Oncotarget. 2017 Apr 20;8(42):73240-73257.
Title: Germline mutations in pancreatic cancer and potential new therapeutic options.
Author: Pihlak, Rille|Valle, Juan W|McNamara, Mairead G
PMID: 29069866
Journal: World J Gastroenterol. 2017 Dec 7;23(45):7945-7951.
Title: Pancreatic acinar cell carcinoma: A review on molecular profiling of patient tumors.
Author: Al-Hader, Ahmad|Al-Rohil, Rami N|Han, Haiyong|Von Hoff, Daniel
PMID: 29259370
Journal: Gut. 2018 Feb;67(2):320-332.
Title: IL-6 and PD-L1 antibody blockade combination therapy reduces tumour progression in murine models of pancreatic cancer.
Author: Mace, Thomas A|Shakya, Reena|Pitarresi, Jason R|Swanson, Benjamin|McQuinn, Christopher W|Loftus, Shannon|Nordquist, Emily|Cruz-Monserrate, Zobeida|Yu, Lianbo|Young, Gregory|Zhong, Xiaoling|Zimmers, Teresa A|Ostrowski, Michael C|Ludwig, Thomas|Bloomston, M
PMID: 27797936
Journal: Fam Cancer. 2018 Apr;17(2):235-245.
Title: The spectrum of genetic variants in hereditary pancreatic cancer includes Fanconi anemia genes.
Author: Slavin, Thomas P|Neuhausen, Susan L|Nehoray, Bita|Niell-Swiller, Mariana|Solomon, Ilana|Rybak, Christina|Blazer, Kathleen|Adamson, Aaron|Yang, Kai|Sand, Sharon|Guerrero-Llamas, Nancy|Castillo, Danielle|Herzog, Josef|Wu, Xiwei|Tao, Shu|Raja, Shivali|Chung,
PMID: 28687971
Journal: Genet Med. 2018 Jan;20(1):119-127.
Title: Prevalence of germ-line mutations in cancer genes among pancreatic cancer patients with a positive family history.
Author: Chaffee, Kari G|Oberg, Ann L|McWilliams, Robert R|Majithia, Neil|Allen, Brian A|Kidd, John|Singh, Nanda|Hartman, Anne-Renee|Wenstrup, Richard J|Petersen, Gloria M
PMID: 28726808
Journal: Gastroenterology. 2018 Feb;154(3):719-722.e3.
Title: Exome-Wide Association Study of Pancreatic Cancer Risk.
Author: Grant, Robert C|Denroche, Robert E|Borgida, Ayelet|Virtanen, Carl|Cook, Natalie|Smith, Alyssa L|Connor, Ashton A|Wilson, Julie M|Peterson, Gloria|Roberts, Nicholas J|Klein, Alison P|Grimmond, Sean M|Biankin, Andrew|Cleary, Sean|Moore, Malcolm|Lemire, Math
PMID: 29074453
Journal: Fam Cancer. 2018 Jan;17(1):101-111.
Title: Development of a high risk pancreatic screening clinic using 3.0 T MRI.
Author: Barnes, Chad A|Krzywda, Elizabeth|Lahiff, Shannon|McDowell, Dena|Christians, Kathleen K|Knechtges, Paul|Tolat, Parag|Hohenwalter, Mark|Dua, Kulwinder|Khan, Abdul H|Evans, Douglas B|Geurts, Jennifer|Tsai, Susan
PMID: 29101607
Journal: Hum Pathol. 2018 Jan;71:135-144.
Title: BRCA1 and BRCA2 expression patterns and prognostic significance in digestive system cancers.
Author: Wang, Gui-Hua|Zhao, Chun-Mei|Huang, Ying|Wang, Wei|Zhang, Shu|Wang, Xudong
PMID: 29126833
Journal: Med Clin (Barc). 2018 Apr 23;150(8):e19-e20.
Title: Familial pancreatic cancer asociated to germline mutation of BRCA2.
Author: Sanchez Bermudez, Ana Isabel|Marin Zafra, Gema|Sarabia Meseguer, M Desamparados
PMID: 29162271
Journal: Gastrointest Endosc. 2018 Jun;87(6):1443-1450.
Title: Pancreatic cancer screening in high-risk individuals with germline genetic mutations.
Author: DaVee, Tomas|Coronel, Emmanuel|Papafragkakis, Charilaos|Thaiudom, Sayam|Lanke, Gandhi|Chakinala, Raja C|Nogueras Gonzalez, Graciela M|Bhutani, Manoop S|Ross, William A|Weston, Brian R|Lee, Jeffrey H
PMID: 29309780
Journal: BMC Cancer. 2018 Feb 13;18(1):179.
Title: Male BRCA mutation carriers: clinical characteristics and cancer spectrum.
Author: Ibrahim, Mohammed|Yadav, Siddhartha|Ogunleye, Foluso|Zakalik, Dana
PMID: 29433453
Journal: J Genet Couns. 2018 Aug;27(4):988-995.
Title: Comparison of Practice Guidelines, BRCAPRO, and Genetic Counselor Estimates to Identify Germline BRCA1 and BRCA2 Mutations in Pancreatic Cancer.
Author: Grant, Robert C|Holter, Spring|Borgida, Ayelet|Dhani, Neesha C|Hedley, David W|Knox, Jennifer J|Akbari, Mohammad R|Zogopoulos, George|Gallinger, Steven
PMID: 29441441
Journal: Oncotarget. 2018 Jan 22;9(14):11592-11603.
Title: MEK inhibition leads to BRCA2 downregulation and sensitization to DNA damaging agents in pancreas and ovarian cancer models.
Author: Vena, Francesca|Jia, Ruochen|Esfandiari, Arman|Garcia-Gomez, Juan J|Rodriguez-Justo, Manuel|Ma, Jianguo|Syed, Sakeena|Crowley, Lindsey|Elenbaas, Brian|Goodstal, Samantha|Hartley, John A|Hochhauser, Daniel
PMID: 29545922
Journal: Oncotarget. 2018 Apr 13;9(28):19817-19825.
Title: Association between homologous recombination repair gene mutations and response to oxaliplatin in pancreatic cancer.
Author: Kondo, Tomohiro|Kanai, Masashi|Kou, Tadayuki|Sakuma, Tomohiro|Mochizuki, Hiroaki|Kamada, Mayumi|Nakatsui, Masahiko|Uza, Norimitsu|Kodama, Yuzo|Masui, Toshihiko|Takaori, Kyoichi|Matsumoto, Shigemi|Miyake, Hidehiko|Okuno, Yasushi|Muto, Manabu
PMID: 29731985
Journal: J Cancer Res Clin Oncol. 2018 Aug;144(8):1503-1507.
Title: Emerging strategies in BRCA-positive pancreatic cancer.
Author: Kowalewski, Adam|Szylberg, Lukasz|Saganek, Michal|Napiontek, Wojciech|Antosik, Paulina|Grzanka, Dariusz
PMID: 29777302
Journal: JAMA. 2018 Jun 19;319(23):2401-2409.
Title: Association Between Inherited Germline Mutations in Cancer Predisposition Genes and Risk of Pancreatic Cancer.
Author: Hu, Chunling|Hart, Steven N|Polley, Eric C|Gnanaolivu, Rohan|Shimelis, Hermela|Lee, Kun Y|Lilyquist, Jenna|Na, Jie|Moore, Raymond|Antwi, Samuel O|Bamlet, William R|Chaffee, Kari G|DiCarlo, John|Wu, Zhong|Samara, Raed|Kasi, Pashtoon M|McWilliams, Robert R|
PMID: 29922827
Journal: Genet Med. 2018 Jul 2. pii: 10.1038/s41436-018-0009-5.
Title: Germline cancer susceptibility gene variants, somatic second hits, and survival outcomes in patients with resected pancreatic cancer.
Author: Yurgelun, Matthew B|Chittenden, Anu B|Morales-Oyarvide, Vicente|Rubinson, Douglas A|Dunne, Richard F|Kozak, Margaret M|Qian, Zhi Rong|Welch, Marisa W|Brais, Lauren K|Da Silva, Annacarolina|Bui, Justin L|Yuan, Chen|Li, Tingting|Li, Wanwan|Masuda, Atsuhiro|
PMID: 29961768
Journal: JCO Precis Oncol. 2018;2018. Epub 2018 May 16.
Title: Rucaparib Monotherapy in Patients With Pancreatic Cancer and a Known Deleterious BRCA Mutation.
Author: Shroff, Rachna T|Hendifar, Andrew|McWilliams, Robert R|Geva, Ravit|Epelbaum, Ron|Rolfe, Lindsey|Goble, Sandra|Lin, Kevin K|Biankin, Andrew V|Giordano, Heidi|Vonderheide, Robert H|Domchek, Susan M
PMID: 30051098
Journal: Pancreas. 2018 Sep;47(8):924-936.
Title: Germline Variants and Risk for Pancreatic Cancer: A Systematic Review and Emerging Concepts.
Author: Zhan, Wei|Shelton, Celeste A|Greer, Phil J|Brand, Randall E|Whitcomb, David C
PMID: 30113427
Journal: Clin Cancer Res. 2018 Aug 21. pii: 1078-0432.CCR-18-1472.
Title: Germline and Somatic DNA Damage Repair Gene Mutations and Overall Survival in Metastatic Pancreatic Adenocarcinoma Patients Treated with FOLFIRINOX.
Author: Sehdev, Amikar|Gbolahan, Olumide|Hancock, Bradley A|Stanley, Melissa|Shahda, Safi|Wan, Jun|Wu, Howard H|Radovich, Milan|O'Neil, Bert H
PMID: 30131383
Journal: Gynecol Obstet Fertil Senol. 2018 Sep 19. pii: S2468-7189(18)30234-4.
Title: [PALB2, a major susceptibility gene for breast cancer].
Author: Piffer, A|Luporsi, E|Mathelin, C
PMID: 30243941
Journal: Oncol Res Treat. 2018;41(10):619-625.
Title: Targeting Defects in the Cellular DNA Damage Response for the Treatment of Pancreatic Ductal Adenocarcinoma.
Author: Schmitt, Anna|Feldmann, Georg|Zander, Thomas|Reinhardt, H Christian
PMID: 30286473