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Journal:
Title: BRCA1- and BRCA2-Associated Hereditary Breast and Ovarian Cancer
Author: Petrucelli, Nancie|Daly, Mary B|Pal, Tuya
PMID: 20301425
Journal: Nat Genet. 1996 Jun;13(2):241-4.
Title: Low incidence of BRCA2 mutations in breast carcinoma and other cancers.
Author: Teng, D H|Bogden, R|Mitchell, J|Baumgard, M|Bell, R|Berry, S|Davis, T|Ha, P C|Kehrer, R|Jammulapati, S|Chen, Q|Offit, K|Skolnick, M H|Tavtigian, S V|Jhanwar, S|Swedlund, B|Wong, A K|Kamb, A
PMID: 8640236
Journal: J Med Genet. 1996 Nov;33(11):889-98.
Title: Pancreatic adenocarcinoma: epidemiology and genetics.
Author: Flanders, T Y|Foulkes, W D
PMID: 8950667
Journal: Nat Genet. 1997 Jan;15(1):103-5.
Title: Variation of risks of breast and ovarian cancer associated with different germline mutations of the BRCA2 gene.
Author: Gayther, S A|Mangion, J|Russell, P|Seal, S|Barfoot, R|Ponder, B A|Stratton, M R|Easton, D
PMID: 8988179
Journal: Mol Med Today. 1997 Apr;3(4):168-74.
Title: Mutations of the BRCA1 and BRCA2 genes and the possibilities for predictive testing.
Author: Gayther, S A|Ponder, B A
PMID: 9134530
Journal: Breast Cancer. 1997 Dec 25;4(4):256-258.
Title: BRCA1 and BRCA2 Germline Mutations in Japanese with Hereditary Breast Cancer Families.
Author: Fukutomi|Ushijima|Inoue|Akashi-Tanaka|Nanasawa|Tsuda
PMID: 11091610
Journal: Oncogene. 1998 Nov 5;17(18):2279-85.
Title: Characterization of a carboxy-terminal BRCA1 interacting protein.
Author: Wong, A K|Ormonde, P A|Pero, R|Chen, Y|Lian, L|Salada, G|Berry, S|Lawrence, Q|Dayananth, P|Ha, P|Tavtigian, S V|Teng, D H|Bartel, P L
PMID: 9811458
Journal: Cancer Res. 2000 Jan 15;60(2):409-16.
Title: Inherited predisposition to pancreatic adenocarcinoma: role of family history and germ-line p16, BRCA1, and BRCA2 mutations.
Author: Lal, G|Liu, G|Schmocker, B|Kaurah, P|Ozcelik, H|Narod, S A|Redston, M|Gallinger, S
PMID: 10667595
Journal: Cancer Res. 2001 Jan 1;61(1):270-7.
Title: Nonhomologous end-joining of ionizing radiation-induced DNA double-stranded breaks in human tumor cells deficient in BRCA1 or BRCA2.
Author: Wang, H|Zeng, Z C|Bui, T A|DiBiase, S J|Qin, W|Xia, F|Powell, S N|Iliakis, G
PMID: 11196174
Journal: Cancer Invest. 2001;19(1):65-75.
Title: The role of genetic factors in the etiology of pancreatic adenocarcinoma: an update.
Author: Chappuis, P O|Ghadirian, P|Foulkes, W D
PMID: 11291558
Journal: Breast Cancer Res. 2002;4(1):R2. Epub 2001 Nov 21.
Title: BRCA1 and BRCA2 mutations in a population-based study of male breast cancer.
Author: Basham, Victoria M|Lipscombe, Julian M|Ward, Joanna M|Gayther, Simon A|Ponder, Bruce A J|Easton, Douglas F|Pharoah, Paul D P
PMID: 11879560
Journal: J Natl Cancer Inst. 2002 Sep 18;94(18):1358-65.
Title: Cancer Incidence in BRCA1 mutation carriers.
Author: Thompson, Deborah|Easton, Douglas F
PMID: 12237281
Journal: Int J Gastrointest Cancer. 2002;31(1-3):99-106.
Title: BRCA2 and pancreatic cancer.
Author: Naderi, Ali|Couch, Fergus J
PMID: 12622420
Journal: Cancer Detect Prev. 2003;27(2):87-93.
Title: Epidemiology of pancreatic cancer: an overview.
Author: Ghadirian, P|Lynch, H T|Krewski, D
PMID: 12670518
Journal: Cancer. 2003 Nov 1;98(9):1947-57.
Title: Familial sarcoma: challenging pedigrees.
Author: Lynch, Henry T|Deters, Carolyn A|Hogg, David|Lynch, Jane F|Kinarsky, Yulia|Gatalica, Zoran
PMID: 14584079
Journal: Cancer Biol Ther. 2004 Feb;3(2):167-9. Epub 2004 Feb 1.
Title: The genetics of FANCC and FANCG in familial pancreatic cancer.
Author: Rogers, Carmelle D|van der Heijden, Michiel S|Brune, Kieran|Yeo, Charles J|Hruban, Ralph H|Kern, Scott E|Goggins, Michael
PMID: 14726700
Journal: J Clin Oncol. 2004 Feb 15;22(4):735-42.
Title: Cancer risks for male carriers of germline mutations in BRCA1 or BRCA2: a review of the literature.
Author: Liede, Alexander|Karlan, Beth Y|Narod, Steven A
PMID: 14966099
Journal: Cytogenet Genome Res. 2004;104(1-4):333-40.
Title: Possible causes of chromosome instability: comparison of chromosomal abnormalities in cancer cell lines with mutations in BRCA1, BRCA2, CHK2 and BUB1.
Author: Grigorova, M|Staines, J M|Ozdag, H|Caldas, C|Edwards, P A W
PMID: 15162061
Journal: Clin Cancer Res. 2004 Jun 1;10(11):3780-7.
Title: Down-regulation of BRCA1 in chronic pancreatitis and sporadic pancreatic adenocarcinoma.
Author: Beger, Carmela|Ramadani, Marco|Meyer, Stephan|Leder, Gerd|Kruger, Martin|Welte, Karl|Gansauge, Frank|Beger, Hans G
PMID: 15173085
Journal: Breast Cancer Res. 2004;6(4):R366-71. Epub 2004 May 14.
Title: No germline mutations in the histone acetyltransferase gene EP300 in BRCA1 and BRCA2 negative families with breast cancer and gastric, pancreatic, or colorectal cancer.
Author: Campbell, Ian G|Choong, David|Chenevix-Trench, Georgia
PMID: 15217503
Journal: Am J Med Genet C Semin Med Genet. 2004 Aug 15;129C(1):5-22.
Title: Inherited predisposition to cancer: a historical overview.
Author: Lynch, Henry T|Shaw, Trudy G|Lynch, Jane F
PMID: 15264268
Journal: Fam Cancer. 2004;3(3-4):233-40.
Title: Familial pancreatic carcinoma in Jews.
Author: Lynch, Henry T|Deters, Carolyn A|Lynch, Jane F|Brand, Randall E
PMID: 15516847
Journal: Ann Oncol. 2004 Dec;15(12):1834-41.
Title: Risk of cancer at sites other than the breast in Swedish families eligible for BRCA1 or BRCA2 mutation testing.
Author: Lorenzo Bermejo, J|Hemminki, K
PMID: 15550590
Journal: Cancer Res. 2005 Mar 15;65(6):2260-8.
Title: Tbx2 is overexpressed and plays an important role in maintaining proliferation and suppression of senescence in melanomas.
Author: Vance, Keith W|Carreira, Suzanne|Brosch, Gerald|Goding, Colin R
PMID: 15781639
Journal: Cancer Genet Cytogenet. 2005 Apr 15;158(2):119-25.
Title: BRCA1 and pancreatic cancer: pedigree findings and their causal relationships.
Author: Lynch, Henry T|Deters, Carolyn A|Snyder, Carrie L|Lynch, Jane F|Villeneuve, Pierre|Silberstein, Julie|Martin, Holly|Narod, Steven A|Brand, Randall E
PMID: 15796958
Journal: Mol Cancer Ther. 2005 Sep;4(9):1338-48.
Title: Modulation of cell cycle and gene expression in pancreatic tumor cell lines by methionine deprivation (methionine stress): implications to the therapy of pancreatic adenocarcinoma.
Author: Kokkinakis, Demetrius M|Liu, Xiaoyan|Neuner, Russell D
PMID: 16170025
Journal: Gut. 2007 May;56(5):601-5. Epub 2006 Sep 14.
Title: Role of BRCA1 and BRCA2 mutations in pancreatic cancer.
Author: Greer, Julia B|Whitcomb, David C
PMID: 16973716
Journal: Cancer. 2007 May 1;109(9):1784-90.
Title: Prophylactic salpingo-oophorectomy in a series of 89 women carrying a BRCA1 or a BRCA2 mutation.
Author: Laki, Fatima|Kirova, Youlia M|This, Pascale|Plancher, Corinne|Asselain, Bernard|Sastre, Xavier|Stoppa-Lyonnet, Dominique|Salmon, Remy
PMID: 17351952
Journal: Cancer Res. 2008 Feb 15;68(4):971-5.
Title: Mutational analysis of thirty-two double-strand DNA break repair genes in breast and pancreatic cancers.
Author: Wang, Xianshu|Szabo, Csilla|Qian, Chiping|Amadio, Peter G|Thibodeau, Stephen N|Cerhan, James R|Petersen, Gloria M|Liu, Wanguo|Couch, Fergus J
PMID: 18281469
Journal: Br J Cancer. 2008 Apr 22;98(8):1457-66.
Title: The BOADICEA model of genetic susceptibility to breast and ovarian cancers: updates and extensions.
Author: Antoniou, A C|Cunningham, A P|Peto, J|Evans, D G|Lalloo, F|Narod, S A|Risch, H A|Eyfjord, J E|Hopper, J L|Southey, M C|Olsson, H|Johannsson, O|Borg, A|Pasini, B|Radice, P|Manoukian, S|Eccles, D M|Tang, N|Olah, E|Anton-Culver, H|Warner, E|Lubinski, J|Gronw
PMID: 18349832
Journal: Genet Test. 2008 Jun;12(2):267-71.
Title: Predominant Ashkenazi BRCA1/2 mutations in families with pancreatic cancer.
Author: Dagan, Efrat
PMID: 18439109
Journal: J Genet Couns. 2008 Aug;17(4):365-72.
Title: Family history of pancreatic cancer in a high-risk cancer clinic: implications for risk assessment.
Author: Hall, Michael J|Dignam, James J|Olopade, Olufunmilayo I
PMID: 18581219
Journal: Hum Genet. 2008 Oct;124(3):271-8.
Title: Germline BRCA1 mutations predispose to pancreatic adenocarcinoma.
Author: Al-Sukhni, Wigdan|Rothenmund, Heidi|Borgida, Ayelet Eppel|Zogopoulos, George|O'Shea, Anne-Marie|Pollett, Aaron|Gallinger, Steven
PMID: 18762988
Journal: Pancreatology. 2008;8(6):558-65.
Title: International registries of families at high risk of pancreatic cancer.
Author: Greenhalf, William|Malats, Nuria|Nilsson, Magnus|Bartsch, Detlef|Neoptolemos, John
PMID: 18818508
Journal: Pol Arch Med Wewn. 2008 Nov;118(11):645-9.
Title: Is there any relationship between BRCA1 gene mutation and pancreatic cancer development?
Author: Lawniczak, Malgorzata|Gawin, Alicja|Bialek, Andrzej|Lubinski, Jan|Starzynska, Teresa
PMID: 19140568
Journal: J Genet Couns. 2009 Feb;18(1):42-8.
Title: The impact of social roles on the experience of men in BRCA1/2 families: implications for counseling.
Author: Daly, Mary B
PMID: 18688698
Journal: Fam Cancer. 2009;8(2):153-8.
Title: Prevalence and characteristics of pancreatic cancer in families with BRCA1 and BRCA2 mutations.
Author: Kim, Daniel H|Crawford, Beth|Ziegler, John|Beattie, Mary S
PMID: 18855126
Journal: Cancer Biol Ther. 2009 Jan;8(2):131-5. Epub 2009 Feb 4.
Title: Absence of germline BRCA1 mutations in familial pancreatic cancer patients.
Author: Axilbund, Jennifer E|Argani, Pedram|Kamiyama, Mihoko|Palmisano, Emily|Raben, Marian|Borges, Michael|Brune, Kieran A|Goggins, Michael|Hruban, Ralph H|Klein, Alison P
PMID: 19029836
Journal: Mutat Res. 2009 Apr 26;663(1-2):84-9.
Title: cDNA analysis demonstrates that the BRCA2 intronic variant IVS4-12del5 is a deleterious mutation.
Author: Zhang, Liying|Bacares, Ruben|Boyar, Sherry|Hudis, Clifford|Nafa, Khedoudja|Offit, Kenneth
PMID: 19070627
Journal: PLoS One. 2009;4(3):e4812.
Title: Potential excess mortality in BRCA1/2 mutation carriers beyond breast, ovarian, prostate, and pancreatic cancers, and melanoma.
Author: Mai, Phuong L|Chatterjee, Nilanjan|Hartge, Patricia|Tucker, Margaret|Brody, Lawrence|Struewing, Jeffery P|Wacholder, Sholom
PMID: 19277124
Journal: Anticancer Drugs. 2009 Aug;20(7):634-8.
Title: Prolonged survival in a patient with BRCA2 associated metastatic pancreatic cancer after exposure to camptothecin: a case report and review of literature.
Author: James, Edward|Waldron-Lynch, Maeve G|Saif, Muhammad Wasif
PMID: 19433978
Journal: Am J Gastroenterol. 2009 Sep;104(9):2175-81.
Title: The yield of first-time endoscopic ultrasonography in screening individuals at a high risk of developing pancreatic cancer.
Author: Poley, J W|Kluijt, I|Gouma, D J|Harinck, F|Wagner, A|Aalfs, C|van Eijck, C H J|Cats, A|Kuipers, E J|Nio, Y|Fockens, P|Bruno, M J
PMID: 19491823
Journal: Cancer Epidemiol Biomarkers Prev. 2009 Sep;18(9):2549-52.
Title: Polymorphic variants in hereditary pancreatic cancer genes are not associated with pancreatic cancer risk.
Author: McWilliams, Robert R|Bamlet, William R|de Andrade, Mariza|Rider, David N|Couch, Fergus J|Cunningham, Julie M|Matsumoto, Martha E|Rabe, Kari G|Hammer, Traci J|Petersen, Gloria M
PMID: 19690177
Journal: Environ Mol Mutagen. 2009 Oct;50(8):672-96.
Title: Nucleation capacity and presence of centrioles define a distinct category of centrosome abnormalities that induces multipolar mitoses in cancer cells.
Author: Difilippantonio, Michael J|Ghadimi, B Michael|Howard, Tamara|Camps, Jordi|Nguyen, Quang Tri|Ferris, Douglas K|Sackett, Dan L|Ried, Thomas
PMID: 19768832
Journal: Cancer Invest. 2010 Feb;28(2):172-80.
Title: In situ protein expression of RRM1, ERCC1, and BRCA1 in metastatic breast cancer patients treated with gemcitabine-based chemotherapy.
Author: Metro, G|Zheng, Z|Fabi, A|Schell, M|Antoniani, B|Mottolese, M|Monteiro, A N|Vici, P|Lara Rivera, S|Boulware, D|Cognetti, F|Bepler, G
PMID: 19968494
Journal: Planta Med. 2010 Aug;76(11):1155-61.
Title: Berberine inhibits cell growth and mediates caspase-independent cell death in human pancreatic cancer cells.
Author: Pinto-Garcia, Lina|Efferth, Thomas|Torres, Amada|Hoheisel, Jorg D|Youns, Mahmoud
PMID: 20455200
Journal: Cancer Res. 2010 Oct 1;70(19):7353-9.
Title: PALB2/FANCN: recombining cancer and Fanconi anemia.
Author: Tischkowitz, Marc|Xia, Bing
PMID: 20858716
Journal: Clin Cancer Res. 2010 Oct 15;16(20):5028-37.
Title: Pancreatic cancer screening in a prospective cohort of high-risk patients: a comprehensive strategy of imaging and genetics.
Author: Verna, Elizabeth C|Hwang, Caroline|Stevens, Peter D|Rotterdam, Heidrun|Stavropoulos, Stavros N|Sy, Carolyn D|Prince, Martin A|Chung, Wendy K|Fine, Robert L|Chabot, John A|Frucht, Harold
PMID: 20876795
Journal: Breast Cancer Res Treat. 2011 Jun;127(2):357-62.
Title: PALB2 analysis in BRCA2-like families.
Author: Adank, M A|van Mil, S E|Gille, J J P|Waisfisz, Q|Meijers-Heijboer, H
PMID: 20582465
Journal: Mol Cancer Ther. 2011 Jan;10(1):3-8.
Title: Personalizing cancer treatment in the age of global genomic analyses: PALB2 gene mutations and the response to DNA damaging agents in pancreatic cancer.
Author: Villarroel, Maria C|Rajeshkumar, N V|Garrido-Laguna, Ignacio|De Jesus-Acosta, Ana|Jones, Sian|Maitra, Anirban|Hruban, Ralph H|Eshleman, James R|Klein, Alison|Laheru, Daniel|Donehower, Ross|Hidalgo, Manuel
PMID: 21135251
Journal: J Natl Cancer Inst. 2011 Feb 16;103(4):334-46.
Title: Therapeutic potential of poly(ADP-ribose) polymerase inhibitor AG014699 in human cancers with mutated or methylated BRCA1 or BRCA2.
Author: Drew, Yvette|Mulligan, Evan A|Vong, Wan-Tse|Thomas, Huw D|Kahn, Samra|Kyle, Suzanne|Mukhopadhyay, Asima|Los, Gerrit|Hostomsky, Zdenek|Plummer, Elizabeth R|Edmondson, Richard J|Curtin, Nicola J
PMID: 21183737
Journal: Toxicol Lett. 2011 Apr 10;202(1):15-22.
Title: A novel in vitro pancreatic carcinogenesis model.
Author: Kang, Hyo Jin|Hong, Young Bin|Kim, Hee Jeong|Yi, Yong Weon|Nath, Raghu G|Chang, Young Soo|Cho, Ho-Chan|Bae, Insoo
PMID: 21256203
Journal: Cancer Res. 2011 Mar 15;71(6):2222-9.
Title: Contribution of inherited mutations in the BRCA2-interacting protein PALB2 to familial breast cancer.
Author: Casadei, Silvia|Norquist, Barbara M|Walsh, Tom|Stray, Sunday|Mandell, Jessica B|Lee, Ming K|Stamatoyannopoulos, John A|King, Mary-Claire
PMID: 21285249
Journal: Fam Cancer. 2011 Jun;10(2):225-31.
Title: PALB2 mutations in familial breast and pancreatic cancer.
Author: Hofstatter, Erin W|Domchek, Susan M|Miron, Alexander|Garber, Judy|Wang, Molin|Componeschi, Kathryn|Boghossian, Leigh|Miron, Penelope L|Nathanson, Katherine L|Tung, Nadine
PMID: 21365267
Journal: Cancer Biol Ther. 2011 Aug 1;12(3):165-8. Epub 2011 Aug 1.
Title: Complete remission, in BRCA2 mutation carrier with metastatic pancreatic adenocarcinoma, treated with cisplatin based therapy.
Author: Sonnenblick, Amir|Kadouri, Luna|Appelbaum, Liat|Peretz, Tamar|Sagi, Michal|Goldberg, Yael|Hubert, Ayala
PMID: 21613821
Journal: Pancreas. 2011 Jul;40(5):730-9.
Title: Increased expression of DNA repair genes in invasive human pancreatic cancer cells.
Author: Mathews, Lesley A|Cabarcas, Stephanie M|Hurt, Elaine M|Zhang, Xiaohu|Jaffee, Elizabeth M|Farrar, William L
PMID: 21633318
Journal: Oncologist. 2011;16(12):1714-20.
Title: Acinar cell carcinoma of the pancreas: new genetic and treatment insights into a rare malignancy.
Author: Lowery, Maeve A|Klimstra, David S|Shia, Jinru|Yu, Kenneth H|Allen, Peter J|Brennan, Murray F|O'Reilly, Eileen M
PMID: 22042785
Journal: Cell Cycle. 2011 Dec 15;10(24):4321-9.
Title: Selective radiosensitization of p53 mutant pancreatic cancer cells by combined inhibition of Chk1 and PARP1.
Author: Vance, Sean|Liu, Erqi|Zhao, Lili|Parsels, Joshua D|Parsels, Leslie A|Brown, Jeffery L|Maybaum, Jonathan|Lawrence, Theodore S|Morgan, Meredith A
PMID: 22134241
Journal: Surgery. 2012 Jan;151(1):70-5.
Title: Intraductal papillary mucinous neoplasm of the pancreas: associated cancers, family history, genetic predisposition?
Author: Lubezky, Nir|Ben-Haim, Menahem|Lahat, Guy|Marmor, Sylvia|Solar, Irit|Brazowski, Eli|Nackache, Richard|Klausner, Joseph M
PMID: 21975290
Journal: Fam Cancer. 2012 Mar;11(1):41-7.
Title: Contribution of germline mutations in the BRCA and PALB2 genes to pancreatic cancer in Italy.
Author: Ghiorzo, P|Pensotti, V|Fornarini, G|Sciallero, S|Battistuzzi, L|Belli, F|Bonelli, L|Borgonovo, G|Bruno, W|Gozza, A|Gargiulo, S|Mastracci, L|Nasti, S|Palmieri, G|Papadia, F|Pastorino, L|Russo, A|Savarino, V|Varesco, L|Bernard, L|Bianchi Scarra, G
PMID: 21989927
Journal: Eur J Hum Genet. 2012 May;20(5):577-9.
Title: Routine testing for PALB2 mutations in familial pancreatic cancer families and breast cancer families with pancreatic cancer is not indicated.
Author: Harinck, Femme|Kluijt, Irma|van Mil, Saskia E|Waisfisz, Quinten|van Os, Theo A M|Aalfs, Cora M|Wagner, Anja|Olderode-Berends, Maran|Sijmons, Rolf H|Kuipers, Ernst J|Poley, Jan-Werner|Fockens, Paul|Bruno, Marco J
PMID: 22166947
Journal: Breast Cancer Res Treat. 2012 Apr;132(3):1119-26.
Title: The KL-VS sequence variant of Klotho and cancer risk in BRCA1 and BRCA2 mutation carriers.
Author: Laitman, Yael|Kuchenbaecker, Karoline B|Rantala, Johanna|Hogervorst, Frans|Peock, Susan|Godwin, Andrew K|Arason, Adalgeir|Kirchhoff, Tomas|Offit, Kenneth|Isaacs, Claudine|Schmutzler, Rita K|Wappenschmidt, Barbara|Nevanlinna, Heli|Chen, Xiaoqing|Chenevix-T
PMID: 22212556
Journal: Breast Cancer Res Treat. 2012 Jun;133(2):725-34.
Title: Molecular and clinical characterization of an in frame deletion of uncertain clinical significance in the BRCA2 gene.
Author: Rath, Michelle G|Fathali-Zadeh, Farnoosh|Langheinz, Anne|Tchatchou, Sandrine|Voigtlander, Theda|Heil, Jorg|Golatta, Michael|Schott, Sarah|Drasseck, Teresa|Behnecke, Anne|Burgemeister, Anna-Lena|Evers, Christina|Bugert, Peter|Junkermann, Hans|Schneeweiss,
PMID: 22228431
Journal: Mol Cell Biol. 2012 Apr;32(8):1506-17.
Title: PALB2 interacts with KEAP1 to promote NRF2 nuclear accumulation and function.
Author: Ma, Jianglin|Cai, Hong|Wu, Tongde|Sobhian, Bijan|Huo, Yanying|Alcivar, Allen|Mehta, Monal|Cheung, Ka Lung|Ganesan, Shridar|Kong, Ah-Ng Tony|Zhang, Donna D|Xia, Bing
PMID: 22331464
Journal: J Med Genet. 2012 Mar;49(3):164-70.
Title: CDKN2A is the main susceptibility gene in Italian pancreatic cancer families.
Author: Ghiorzo, Paola|Fornarini, Giuseppe|Sciallero, Stefania|Battistuzzi, Linda|Belli, Fiorenza|Bernard, Loris|Bonelli, Luigina|Borgonovo, Giacomo|Bruno, William|De Cian, Franco|Decensi, Andrea|Filauro, Marco|Faravelli, Francesca|Gozza, Alberto|Gargiulo, Sara|M
PMID: 22368299
Journal: Breast Cancer Res Treat. 2012 Jun;133(3):1153-7.
Title: Recurrent germline mutations in BRCA1 and BRCA2 genes in high risk families in Israel.
Author: Laitman, Yael|Simeonov, Monica|Herskovitz, Liron|Kushnir, Anya|Shimon-Paluch, Shani|Kaufman, Bella|Zidan, Jamal|Friedman, Eitan
PMID: 22399190
Journal: Bull Cancer. 2012 Apr 1;99(4):417-23.
Title: [What management for the asymptomatic men carriers of BRCA1 or 2 mutation? Results of a survey in the French oncogenetic centers].
Author: Brachot-Simeonova, Iglika|Morin, Gilles|Gillaux, Claire|Demeer, Benedicte|Gondry, Jean|Mathieu, Michele|Fauvet, Raffaele
PMID: 22429936
Journal: Autophagy. 2012 Jun;8(6):989-91.
Title: AGER/RAGE-mediated autophagy promotes pancreatic tumorigenesis and bioenergetics through the IL6-pSTAT3 pathway.
Author: Kang, Rui|Tang, Daolin|Lotze, Michael T|Zeh, Herbert J 3rd
PMID: 22722139
Journal: Cancer J. 2012 Jul-Aug;18(4):350-4.
Title: Genetic testing by cancer site: pancreas.
Author: Axilbund, Jennifer E|Wiley, Elizabeth A
PMID: 22846737
Journal: J Breast Cancer. 2012 Sep;15(3):283-7.
Title: Associations between BRCA Mutations in High-Risk Breast Cancer Patients and Familial Cancers Other than Breast or Ovary.
Author: Noh, Jae Myoung|Choi, Doo Ho|Baek, Hyejin|Nam, Seok Jin|Lee, Jeong Eon|Kim, Jong Won|Ki, Chang-Seok|Park, Won|Huh, Seung Jae
PMID: 23091540
Journal: Br J Cancer. 2012 Dec 4;107(12):2005-9.
Title: The incidence of pancreatic cancer in BRCA1 and BRCA2 mutation carriers.
Author: Iqbal, J|Ragone, A|Lubinski, J|Lynch, H T|Moller, P|Ghadirian, P|Foulkes, W D|Armel, S|Eisen, A|Neuhausen, S L|Senter, L|Singer, C F|Ainsworth, P|Kim-Sing, C|Tung, N|Friedman, E|Llacuachaqui, M|Ping, S|Narod, S A
PMID: 23099806
Journal: Cancer J. 2012 Nov-Dec;18(6):485-91.
Title: Inherited pancreatic cancer syndromes.
Author: Solomon, Sheila|Das, Siddhartha|Brand, Randall|Whitcomb, David C
PMID: 23187834
Journal: Cancer Res. 2013 Jan 15;73(2):885-96.
Title: Hypomethylating therapy in an aggressive stroma-rich model of pancreatic carcinoma.
Author: Shakya, Reena|Gonda, Tamas|Quante, Michael|Salas, Martha|Kim, Samuel|Brooks, Jenna|Hirsch, Steffen|Davies, Justine|Cullo, Angelica|Olive, Kenneth|Wang, Timothy C|Szabolcs, Matthias|Tycko, Benjamin|Ludwig, Thomas
PMID: 23204224
Journal: Cancer Epidemiol Biomarkers Prev. 2013 May;22(5):803-11.
Title: Risk of pancreatic cancer in breast cancer families from the breast cancer family registry.
Author: Mocci, Evelina|Milne, Roger L|Mendez-Villamil, Elena Yuste|Hopper, John L|John, Esther M|Andrulis, Irene L|Chung, Wendy K|Daly, Mary|Buys, Saundra S|Malats, Nuria|Goldgar, David E
PMID: 23456555
Journal: Hered Cancer Clin Pract. 2013 Apr 1;11(1):2.
Title: Systemic treatment for hereditary cancers: a 2012 update.
Author: Imyanitov, Evgeny N|Byrski, Tomasz
PMID: 23548133
Journal: Bioinformatics. 2013 Jun 15;29(12):1553-61.
Title: Systematic tracking of dysregulated modules identifies novel genes in cancer.
Author: Srihari, Sriganesh|Ragan, Mark A
PMID: 23613489
Journal: Proc Natl Acad Sci U S A. 2013 May 21;110(21):8632-7.
Title: Palb2 synergizes with Trp53 to suppress mammary tumor formation in a model of inherited breast cancer.
Author: Bowman-Colin, Christian|Xia, Bing|Bunting, Samuel|Klijn, Christiaan|Drost, Rinske|Bouwman, Peter|Fineman, Laura|Chen, Xixi|Culhane, Aedin C|Cai, Hong|Rodig, Scott J|Bronson, Roderick T|Jonkers, Jos|Nussenzweig, Andre|Kanellopoulou, Chryssa|Livingston, Dav
PMID: 23657012
Journal: Clin Cancer Res. 2013 Jul 1;19(13):3396-403.
Title: High prevalence of BRCA1 and BRCA2 germline mutations with loss of heterozygosity in a series of resected pancreatic adenocarcinoma and other neoplastic lesions.
Author: Lucas, Aimee L|Shakya, Reena|Lipsyc, Marla D|Mitchel, Elana B|Kumar, Sheila|Hwang, Caroline|Deng, Liyong|Devoe, Catherine|Chabot, John A|Szabolcs, Matthias|Ludwig, Thomas|Chung, Wendy K|Frucht, Harold
PMID: 23658460
Journal: Pancreas. 2013 Jul;42(5):740-59.
Title: Sweating the small stuff: microRNAs and genetic changes define pancreatic cancer.
Author: Tang, Siuwah|Bonaroti, Jillian|Unlu, Sebnem|Liang, Xiaoyan|Tang, Daolin|Zeh, Herbert J|Lotze, Michael T
PMID: 23774697
Journal: PLoS One. 2013 Jul 23;8(7):e67538.
Title: Analysis of PALB2 gene in BRCA1/BRCA2 negative Spanish hereditary breast/ovarian cancer families with pancreatic cancer cases.
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Title: Network-based analysis of omics with multi-objective optimization.
Author: Mosca, Ettore|Milanesi, Luciano
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Journal: Clin Genet. 2014 Jan;85(1):18-20.
Title: Delineating the effects BRCA1 and BRCA2 loss of heterozygosity in pancreatic cancer progression.
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Title: PARP Inhibitors for BRCA1/2 mutation-associated and BRCA-like malignancies.
Author: Lee, J-M|Ledermann, J A|Kohn, E C
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Title: Characteristics of individuals with breast cancer rearrangements in BRCA1 and BRCA2.
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Title: Epigenetic changes associated with neoplasms of the exocrine and endocrine pancreas.
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Title: BRCA1 and BRCA2 germline mutations are frequently demonstrated in both high-risk pancreatic cancer screening and pancreatic cancer cohorts.
Author: Lucas, Aimee L|Frado, Laura E|Hwang, Caroline|Kumar, Sheila|Khanna, Lauren G|Levinson, Elana J|Chabot, John A|Chung, Wendy K|Frucht, Harold
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Journal: Mol Cancer. 2014 Apr 28;13:94.
Title: The negative interplay between Aurora A/B and BRCA1/2 controls cancer cell growth and tumorigenesis via distinct regulation of cell cycle progression, cytokinesis, and tetraploidy.
Author: Wang, Yan|Wang, Ziliang|Qi, Zihao|Yin, Sheng|Zhang, Na|Liu, Yang|Liu, Mingming|Meng, Jiao|Zang, Rongyu|Zhang, Zhen|Yang, Gong
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Title: [Hereditary predisposition to cancers of the digestive tract, breast, gynecological and gonadal: focus on the Peutz-Jeghers].
Author: Turpin, Anthony|Cattan, Stephane|Leclerc, Julie|Wacrenier, Agnes|Manouvrier-Hanu, Sylvie|Buisine, Marie-Pierre|Lejeune-Dumoulin, Sophie
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Journal: Br J Cancer. 2014 Sep 9;111(6):1132-8.
Title: Overall survival and clinical characteristics of pancreatic cancer in BRCA mutation carriers.
Author: Golan, T|Kanji, Z S|Epelbaum, R|Devaud, N|Dagan, E|Holter, S|Aderka, D|Paluch-Shimon, S|Kaufman, B|Gershoni-Baruch, R|Hedley, D|Moore, M J|Friedman, E|Gallinger, S
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Title: PARP-inhibitors in BRCA-associated pancreatic cancer.
Author: Bhalla, Anshul|Saif, Muhammad Wasif
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Title: Cancers associated with BRCA1 and BRCA2 mutations other than breast and ovarian.
Author: Mersch, Jacqueline|Jackson, Michelle A|Park, Minjeong|Nebgen, Denise|Peterson, Susan K|Singletary, Claire|Arun, Banu K|Litton, Jennifer K
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Journal: Genet Med. 2015 Jul;17(7):569-77.
Title: BRCA1, BRCA2, PALB2, and CDKN2A mutations in familial pancreatic cancer: a PACGENE study.
Author: Zhen, David B|Rabe, Kari G|Gallinger, Steven|Syngal, Sapna|Schwartz, Ann G|Goggins, Michael G|Hruban, Ralph H|Cote, Michele L|McWilliams, Robert R|Roberts, Nicholas J|Cannon-Albright, Lisa A|Li, Donghui|Moyes, Kelsey|Wenstrup, Richard J|Hartman, Anne-Rene
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Journal: J Clin Oncol. 2015 Jan 20;33(3):244-50.
Title: Olaparib monotherapy in patients with advanced cancer and a germline BRCA1/2 mutation.
Author: Kaufman, Bella|Shapira-Frommer, Ronnie|Schmutzler, Rita K|Audeh, M William|Friedlander, Michael|Balmana, Judith|Mitchell, Gillian|Fried, Georgeta|Stemmer, Salomon M|Hubert, Ayala|Rosengarten, Ora|Steiner, Mariana|Loman, Niklas|Bowen, Karin|Fielding, Anitr
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Journal: Virchows Arch. 2015 Feb;466(2):237-41.
Title: Basaloid carcinoma of the pancreas--clinicopathological presentation and oncogenetic snapshot of a rare entity.
Author: Szasz, A Marcell|Szirtes, Ildiko|Tihanyi, Balazs|Barkaszi, Bernadett|Baranyai, Zsolt|Tihanyi, Tibor|Harsanyi, Laszlo|Timar, Jozsef|Kulka, Janina
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Journal: Gastroenterology. 2015 Mar;148(3):556-64.
Title: Prevalence of germline mutations in cancer predisposition genes in patients with pancreatic cancer.
Author: Grant, Robert C|Selander, Iris|Connor, Ashton A|Selvarajah, Shamini|Borgida, Ayelet|Briollais, Laurent|Petersen, Gloria M|Lerner-Ellis, Jordan|Holter, Spring|Gallinger, Steven
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Journal: Fam Cancer. 2015 Sep;14(3):341-8.
Title: Analysis of PALB2 in a cohort of Italian breast cancer patients: identification of a novel PALB2 truncating mutation.
Author: Vietri, Maria Teresa|Caliendo, Gemma|Schiano, Concetta|Casamassimi, Amelia|Molinari, Anna Maria|Napoli, Claudio|Cioffi, Michele
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Journal: Nature. 2015 Feb 26;518(7540):495-501.
Title: Whole genomes redefine the mutational landscape of pancreatic cancer.
Author: Waddell, Nicola|Pajic, Marina|Patch, Ann-Marie|Chang, David K|Kassahn, Karin S|Bailey, Peter|Johns, Amber L|Miller, David|Nones, Katia|Quek, Kelly|Quinn, Michael C J|Robertson, Alan J|Fadlullah, Muhammad Z H|Bruxner, Tim J C|Christ, Angelika N|Harliwong,
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Journal: Breast Cancer Res Treat. 2015 Apr;150(3):631-5.
Title: Cancer risks in Jewish male BRCA1 and BRCA2 mutation carriers.
Author: Laitman, Yael|Keinan Boker, Lital|Liphsitz, Irena|Weissglas-Volkov, Daphna|Litz-Philipsborn, Shira|Schayek, Hagit|Friedman, Eitan
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Journal: JAMA Surg. 2015 Jun;150(6):512-8.
Title: Short-term Results of a Magnetic Resonance Imaging-Based Swedish Screening Program for Individuals at Risk for Pancreatic Cancer.
Author: Del Chiaro, Marco|Verbeke, Caroline S|Kartalis, Nikolaos|Pozzi Mucelli, Raffaella|Gustafsson, Peter|Hansson, Johan|Haas, Stephan L|Segersvard, Ralf|Andren-Sandberg, Ake|Lohr, J-Matthias
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Journal: Oncotarget. 2015 May 10;6(13):11575-84.
Title: Autoimmune response to PARP and BRCA1/BRCA2 in cancer.
Author: Zhu, Qing|Han, Su-Xia|Zhou, Cong-Ya|Cai, Meng-Jiao|Dai, Li-Ping|Zhang, Jian-Ying
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Journal: Clin Cancer Res. 2015 May 1;21(9):2029-37.
Title: Precision Medicine for Advanced Pancreas Cancer: The Individualized Molecular Pancreatic Cancer Therapy (IMPaCT) Trial.
Author: Chantrill, Lorraine A|Nagrial, Adnan M|Watson, Clare|Johns, Amber L|Martyn-Smith, Mona|Simpson, Skye|Mead, Scott|Jones, Marc D|Samra, Jaswinder S|Gill, Anthony J|Watson, Nicole|Chin, Venessa T|Humphris, Jeremy L|Chou, Angela|Brown, Belinda|Morey, Adrienne
PMID: 25896973
Journal: Oncologist. 2015 Jun;20(6):593-7.
Title: BRCAPRO 6.0 Model Validation in Male Patients Presenting for BRCA Testing.
Author: Mitri, Zahi I|Jackson, Michelle|Garby, Carolyn|Song, Juhee|Giordano, Sharon H|Hortobagyi, Gabriel N|Singletary, Claire N|Hashmi, S Shahrukh|Arun, Banu K|Litton, Jennifer K
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Journal: J Clin Oncol. 2015 Oct 1;33(28):3080-1.
Title: Assessing the Significance of BRCA1 and BRCA2 Mutations in Pancreatic Cancer.
Author: Carnevale, Julia|Ashworth, Alan
PMID: 25987697
Journal: Sultan Qaboos Univ Med J. 2015 May;15(2):e218-25. Epub 2015 May 28.
Title: Predicting the Pathogenic Potential of BRCA1 and BRCA2 Gene Variants Identified in Clinical Genetic Testing.
Author: Brookes, Clare|Lai, Stella|Doherty, Elaine|Love, Donald R
PMID: 26052455
Journal: Cancer Genet. 2015 Jul-Aug;208(7-8):374-81.
Title: Exome-level comparison of primary well-differentiated neuroendocrine tumors and their cell lines.
Author: Boora, Ganesh K|Kanwar, Rahul|Kulkarni, Amit A|Pleticha, Josef|Ames, Matthew|Schroth, Gary|Beutler, Andreas S|Banck, Michaela S
PMID: 26087898
Journal: Nat Genet. 2015 Aug;47(8):911-6.
Title: Common variation at 2p13.3, 3q29, 7p13 and 17q25.1 associated with susceptibility to pancreatic cancer.
Author: Childs, Erica J|Mocci, Evelina|Campa, Daniele|Bracci, Paige M|Gallinger, Steven|Goggins, Michael|Li, Donghui|Neale, Rachel E|Olson, Sara H|Scelo, Ghislaine|Amundadottir, Laufey T|Bamlet, William R|Bijlsma, Maarten F|Blackford, Amanda|Borges, Michael|Brenn
PMID: 26098869
Journal: Br J Cancer. 2015 Jul 28;113(3):425-32.
Title: BRCA1 and BRCA2 mutations sensitize to chemotherapy in patient-derived pancreatic cancer xenografts.
Author: Lohse, I|Borgida, A|Cao, P|Cheung, M|Pintilie, M|Bianco, T|Holter, S|Ibrahimov, E|Kumareswaran, R|Bristow, R G|Tsao, M-S|Gallinger, S|Hedley, D W
PMID: 26180923
Journal: Eur J Cancer. 2015 Sep;51(14):1911-7.
Title: PanGen-Fam: Spanish registry of hereditary pancreatic cancer.
Author: Mocci, E|Guillen-Ponce, C|Earl, J|Marquez, M|Solera, J|Salazar-Lopez, M-T|Calcedo-Arnaiz, C|Vazquez-Sequeiros, E|Montans, J|Munoz-Beltran, M|Vicente-Bartulos, A|Gonzalez-Gordaliza, C|Sanjuanbenito, A|Guerrero, C|Mendia, E|Lisa, E|Lobo, E|Martinez, J C|Rea
PMID: 26212471
Journal: Expert Rev Anticancer Ther. 2015;15(10):1223-31.
Title: Pancreatic cancer: BRCA mutation and personalized treatment.
Author: Luo, Guopei|Lu, Yu|Jin, Kaizhou|Cheng, He|Guo, Meng|Liu, Zuqiang|Long, Jiang|Liu, Chen|Ni, Quanxing|Yu, Xianjun
PMID: 26402249
Journal: Cancer. 2015 Dec 15;121(24):4382-8.
Title: Identification of germline genetic mutations in patients with pancreatic cancer.
Author: Salo-Mullen, Erin E|O'Reilly, Eileen M|Kelsen, David P|Ashraf, Asad M|Lowery, Maeve A|Yu, Kenneth H|Reidy, Diane L|Epstein, Andrew S|Lincoln, Anne|Saldia, Amethyst|Jacobs, Lauren M|Rau-Murthy, Rohini|Zhang, Liying|Kurtz, Robert C|Saltz, Leonard|Offit, Ken
PMID: 26440929
Journal: Cell Cycle. 2015;14(23):3713-24.
Title: MEK inhibitor GSK1120212-mediated radiosensitization of pancreatic cancer cells involves inhibition of DNA double-strand break repair pathways.
Author: Estrada-Bernal, Adriana|Chatterjee, Moumita|Haque, S Jaharul|Yang, Linlin|Morgan, Meredith A|Kotian, Shweta|Morrell, David|Chakravarti, Arnab|Williams, Terence M
PMID: 26505547
Journal: Nat Commun. 2015 Oct 29;6:8683.
Title: A mutational signature in gastric cancer suggests therapeutic strategies.
Author: Alexandrov, Ludmil B|Nik-Zainal, Serena|Siu, Hoi Cheong|Leung, Suet Yi|Stratton, Michael R
PMID: 26511885
Journal: Int J Clin Oncol. 2016 Apr;21(2):270-275.
Title: Analysis of PALB2 mutations in 155 Japanese patients with breast and/or ovarian cancer.
Author: Nakagomi, Hiroshi|Sakamoto, Ikuko|Hirotsu, Yosuke|Amemiya, Kenji|Mochiduki, Hitoshi|Omata, Masao
PMID: 26411315
Journal: Expert Opin Ther Targets. 2016;20(3):341-59.
Title: Molecular signature of pancreatic adenocarcinoma: an insight from genotype to phenotype and challenges for targeted therapy.
Author: Sahin, Ibrahim H|Iacobuzio-Donahue, Christine A|O'Reilly, Eileen M
PMID: 26439702
Journal: Cancer Epidemiol Biomarkers Prev. 2016 Jan;25(1):207-11.
Title: Prevalence of Pathogenic Mutations in Cancer Predisposition Genes among Pancreatic Cancer Patients.
Author: Hu, Chunling|Hart, Steven N|Bamlet, William R|Moore, Raymond M|Nandakumar, Kannabiran|Eckloff, Bruce W|Lee, Yean K|Petersen, Gloria M|McWilliams, Robert R|Couch, Fergus J
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Journal: Cancer. 2016 Jan 15;122(2):304-11.
Title: Inherited mutations in cancer susceptibility genes are common among survivors of breast cancer who develop therapy-related leukemia.
Author: Churpek, Jane E|Marquez, Rafael|Neistadt, Barbara|Claussen, Kimberly|Lee, Ming K|Churpek, Matthew M|Huo, Dezheng|Weiner, Howard|Bannerjee, Mekhala|Godley, Lucy A|Le Beau, Michelle M|Pritchard, Colin C|Walsh, Tom|King, Mary-Claire|Olopade, Olufunmilayo I|L
PMID: 26641009
Journal: Klin Onkol. 2016;29 Suppl 1:S9-13.
Title: [Recommended Extension of Indication Criteria for Genetic Testing of BRCA1 and BRCA2 Mutations in Hereditary Breast and Ovarian Cancer Syndrome].
Author: Foretova, L|Machackova, E|Palacova, M|Navratilova, M|Svoboda, M|Petrakova, K
PMID: 26691937
Journal: Klin Onkol. 2016;29 Suppl 1:S14-21.
Title: [Hereditary Breast and Ovarian Cancer Syndrome].
Author: Petrakova, K|Palacova, M|Schneiderova, M|Standara, M
PMID: 26691938
Journal: Klin Onkol. 2016;29 Suppl 1:S31-4.
Title: [PALB2 as Another Candidate Gene for Genetic Testing in Patients with Hereditary Breast Cancer in Czech Republic].
Author: Janatova, M|Borecka, M|Soukupova, J|Kleiblova, P|Stribrna, J|Vocka, M|Zemankova, P|Panczak, A|Vesela, K|Soucek, P|Foretova, L|Kleibl, Z
PMID: 26691940
Journal: Med Oncol. 2016 Jan;33(1):4.
Title: Biweekly gemcitabine and low-dose cisplatin in the treatment of locally advanced or metastatic pancreatic cancer patients: a single institute experience.
Author: Lundberg, Jordan|Reardon, Joshua|Blazer, Marlo|Phillips, Gary|Bekaii-Saab, Tanios
PMID: 26696390
Journal: Ann Surg Oncol. 2016 May;23(5):1729-35.
Title: Statewide Retrospective Review of Familial Pancreatic Cancer in Delaware, and Frequency of Genetic Mutations in Pancreatic Cancer Kindreds.
Author: Catts, Zohra Ali-Khan|Baig, Muhammad Khurram|Milewski, Becky|Keywan, Christine|Guarino, Michael|Petrelli, Nicholas
PMID: 26727920
Journal: Expert Rev Gastroenterol Hepatol. 2016 Aug;10(8):893-905.
Title: Genomic instability in pancreatic adenocarcinoma: a new step towards precision medicine and novel therapeutic approaches.
Author: Sahin, Ibrahim H|Lowery, Maeve A|Stadler, Zsofia K|Salo-Mullen, Erin|Iacobuzio-Donahue, Christine A|Kelsen, David P|O'Reilly, Eileen M
PMID: 26881472
Journal: PLoS One. 2016 Mar 25;11(3):e0152280.
Title: Phosphoproteome Analysis of Invasion and Metastasis-Related Factors in Pancreatic Cancer Cells.
Author: Tan, Xiaodong|Liu, Peng|Huang, Yinpeng|Zhou, Lei|Yang, Yifan|Wang, Huaitao|Yu, Boqiang|Meng, Xiangli|Zhang, Xiaobo|Gao, Feng
PMID: 27014871
Journal: Int J Cancer. 2016 Aug 1;139(3):601-6.
Title: Do founder mutations characteristic of some cancer sites also predispose to pancreatic cancer?
Author: Lener, Marcin R|Scott, Rodney J|Kluzniak, Wojciech|Baszuk, Piotr|Cybulski, Cezary|Wiechowska-Kozlowska, Anna|Huzarski, Tomasz|Byrski, Tomasz|Kladny, Jozef|Pietrzak, Sandra|Soluch, Agnieszka|Jakubowska, Anna|Lubinski, Jan
PMID: 27038244
Journal: Scientifica (Cairo). 2016;2016:5619358.
Title: Frequency and Significance of Abnormal Pancreatic Imaging in Patients with BRCA1 and BRCA2 Genetic Mutations.
Author: Chahla, Elie|Cheesman, Antonio|Mahon, Suzanne M|Garrett, Robert W|Bradenham, Ben P Jr|Schwartz, Theresa L|Omran, Louay|Taylor, Jason R|Alkaade, Samer
PMID: 27069714
Journal: J Clin Oncol. 2016 Jun 10;34(17):2010-9.
Title: Benefit of Surveillance for Pancreatic Cancer in High-Risk Individuals: Outcome of Long-Term Prospective Follow-Up Studies From Three European Expert Centers.
Author: Vasen, Hans|Ibrahim, Isaura|Ponce, Carmen Guillen|Slater, Emily P|Matthai, Elvira|Carrato, Alfredo|Earl, Julie|Robbers, Kristin|van Mil, Anneke M|Potjer, Thomas|Bonsing, Bert A|de Vos Tot Nederveen Cappel, Wouter H|Bergman, Wilma|Wasser, Martin|Morreau, H
PMID: 27114589
Journal: Oncologist. 2016 Jul;21(7):869-74.
Title: Cancer Incidence in First- and Second-Degree Relatives of BRCA1 and BRCA2 Mutation Carriers.
Author: Streff, Haley|Profato, Jessica|Ye, Yuanqing|Nebgen, Denise|Peterson, Susan K|Singletary, Claire|Arun, Banu K|Litton, Jennifer K
PMID: 27306910
Journal: Climacteric. 2016 Oct;19(5):419-22.
Title: Hormone therapy after prophylactic risk-reducing bilateral salpingo-oophorectomy in women who have BRCA gene mutation.
Author: Guidozzi, F
PMID: 27426853
Journal: PLoS One. 2016 Aug 17;11(8):e0161438.
Title: Analysis of Founder Mutations in Rare Tumors Associated With Hereditary Breast/Ovarian Cancer Reveals a Novel Association of BRCA2 Mutations with Ampulla of Vater Carcinomas.
Author: Pinto, Pedro|Peixoto, Ana|Santos, Catarina|Rocha, Patricia|Pinto, Carla|Pinheiro, Manuela|Leca, Luis|Martins, Ana Teresa|Ferreira, Veronica|Bartosch, Carla|Teixeira, Manuel R
PMID: 27532258
Journal: J Gastrointest Oncol. 2016 Oct;7(5):738-749.
Title: Is it time to split strategies to treat homologous recombinant deficiency in pancreas cancer?
Author: Teo, Min Yuen|O'Reilly, Eileen M
PMID: 27747088
Journal: Oncology (Williston Park). 2016 Oct 15;30(10):896-904.
Title: Prevention and Screening in Hereditary Breast and Ovarian Cancer.
Author: Zeichner, Simon B|Stanislaw, Christine|Meisel, Jane L
PMID: 27753056
Journal: Cancer Res Treat. 2017 Apr;49(2):430-436.
Title: The Prevalence of Founder Mutations among Individuals from Families with Familial Pancreatic Cancer Syndrome.
Author: Lener, Marcin R|Kashyap, Aniruddh|Kluzniak, Wojciech|Cybulski, Cezary|Soluch, Agnieszka|Pietrzak, Sandra|Huzarski, Tomasz|Gronwald, Jacek|Lubinski, Jan
PMID: 27488870
Journal: Br J Cancer. 2017 Mar 14;116(6):697-702.
Title: Overall survival and clinical characteristics of BRCA mutation carriers with stage I/II pancreatic cancer.
Author: Golan, Talia|Sella, Tal|O'Reilly, Eileen M|Katz, Matthew H G|Epelbaum, Ron|Kelsen, David P|Borgida, Ayelet|Maynard, Hannah|Kindler, Hedy|Friedmen, Eitan|Javle, Milind|Gallinger, Steven
PMID: 28183138
Journal: Cancer Metastasis Rev. 2017 Mar;36(1):77-90.
Title: Identification, genetic testing, and management of hereditary melanoma.
Author: Leachman, Sancy A|Lucero, Olivia M|Sampson, Jone E|Cassidy, Pamela|Bruno, William|Queirolo, Paola|Ghiorzo, Paola
PMID: 28283772
Journal: Nat Med. 2017 Apr;23(4):517-525.
Title: HRDetect is a predictor of BRCA1 and BRCA2 deficiency based on mutational signatures.
Author: Davies, Helen|Glodzik, Dominik|Morganella, Sandro|Yates, Lucy R|Staaf, Johan|Zou, Xueqing|Ramakrishna, Manasa|Martin, Sancha|Boyault, Sandrine|Sieuwerts, Anieta M|Simpson, Peter T|King, Tari A|Raine, Keiran|Eyfjord, Jorunn E|Kong, Gu|Borg, Ake|Birney, Ewa
PMID: 28288110
Journal: Oncotarget. 2017 May 30;8(22):36033-36039.
Title: BRCA1 missense polymorphisms are associated with poor prognosis of pancreatic cancer patients in a Chinese population.
Author: Zhu, Ying|Zhai, Kan|Ke, Juntao|Li, Jiaoyuan|Gong, Yajie|Yang, Yang|Tian, Jianbo|Zhang, Yi|Zou, Danyi|Peng, Xiating|Gong, Jing|Zhong, Rong|Huang, Kun|Chang, Jiang|Miao, Xiaoping
PMID: 28415599
Journal: Annu Rev Genomics Hum Genet. 2017 Aug 31;18:201-227.
Title: Application of Panel-Based Tests for Inherited Risk of Cancer.
Author: Shah, Payal D|Nathanson, Katherine L
PMID: 28504904
Journal: Cancer Epidemiol Biomarkers Prev. 2017 Oct;26(10):1540-1548.
Title: Impact of Sixteen Established Pancreatic Cancer Susceptibility Loci in American Jews.
Author: Streicher, Samantha A|Klein, Alison P|Olson, Sara H|Amundadottir, Laufey T|DeWan, Andrew T|Zhao, Hongyu|Risch, Harvey A
PMID: 28754795
Journal: J Clin Oncol. 2017 Oct 20;35(30):3382-3390.
Title: Deleterious Germline Mutations in Patients With Apparently Sporadic Pancreatic Adenocarcinoma.
Author: Shindo, Koji|Yu, Jun|Suenaga, Masaya|Fesharakizadeh, Shahriar|Cho, Christy|Macgregor-Das, Anne|Siddiqui, Abdulrehman|Witmer, P Dane|Tamura, Koji|Song, Tae Jun|Navarro Almario, Jose Alejandro|Brant, Aaron|Borges, Michael|Ford, Madeline|Barkley, Thomas|He,
PMID: 28767289
Journal: J Natl Compr Canc Netw. 2017 Aug;15(8):1063-1069.
Title: DNA Repair Dysfunction in Pancreatic Cancer: A Clinically Relevant Subtype for Drug Development.
Author: Golan, Talia|Javle, Milind
PMID: 28784866
Journal: Int J Mol Sci. 2017 Aug 31;18(9). pii: ijms18091886.
Title: The Role of PALB2 in the DNA Damage Response and Cancer Predisposition.
Author: Nepomuceno, Thales C|De Gregoriis, Giuliana|de Oliveira, Francisco M Bastos|Suarez-Kurtz, Guilherme|Monteiro, Alvaro N|Carvalho, Marcelo A
PMID: 28858227
Journal: Oncotarget. 2017 Apr 20;8(42):73240-73257.
Title: Germline mutations in pancreatic cancer and potential new therapeutic options.
Author: Pihlak, Rille|Valle, Juan W|McNamara, Mairead G
PMID: 29069866
Journal: Genet Med. 2018 Jan;20(1):119-127.
Title: Prevalence of germ-line mutations in cancer genes among pancreatic cancer patients with a positive family history.
Author: Chaffee, Kari G|Oberg, Ann L|McWilliams, Robert R|Majithia, Neil|Allen, Brian A|Kidd, John|Singh, Nanda|Hartman, Anne-Renee|Wenstrup, Richard J|Petersen, Gloria M
PMID: 28726808
Journal: Fam Cancer. 2018 Jan;17(1):101-111.
Title: Development of a high risk pancreatic screening clinic using 3.0 T MRI.
Author: Barnes, Chad A|Krzywda, Elizabeth|Lahiff, Shannon|McDowell, Dena|Christians, Kathleen K|Knechtges, Paul|Tolat, Parag|Hohenwalter, Mark|Dua, Kulwinder|Khan, Abdul H|Evans, Douglas B|Geurts, Jennifer|Tsai, Susan
PMID: 29101607
Journal: Gastrointest Endosc. 2018 Jun;87(6):1443-1450.
Title: Pancreatic cancer screening in high-risk individuals with germline genetic mutations.
Author: DaVee, Tomas|Coronel, Emmanuel|Papafragkakis, Charilaos|Thaiudom, Sayam|Lanke, Gandhi|Chakinala, Raja C|Nogueras Gonzalez, Graciela M|Bhutani, Manoop S|Ross, William A|Weston, Brian R|Lee, Jeffrey H
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Journal: BMC Cancer. 2018 Feb 13;18(1):179.
Title: Male BRCA mutation carriers: clinical characteristics and cancer spectrum.
Author: Ibrahim, Mohammed|Yadav, Siddhartha|Ogunleye, Foluso|Zakalik, Dana
PMID: 29433453
Journal: J Genet Couns. 2018 Aug;27(4):988-995.
Title: Comparison of Practice Guidelines, BRCAPRO, and Genetic Counselor Estimates to Identify Germline BRCA1 and BRCA2 Mutations in Pancreatic Cancer.
Author: Grant, Robert C|Holter, Spring|Borgida, Ayelet|Dhani, Neesha C|Hedley, David W|Knox, Jennifer J|Akbari, Mohammad R|Zogopoulos, George|Gallinger, Steven
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Journal: J Natl Cancer Inst. 2018 Feb 28. pii: 4915401.
Title: Prospective Evaluation of Germline Alterations in Patients With Exocrine Pancreatic Neoplasms.
Author: Lowery, Maeve A|Wong, Winston|Jordan, Emmet J|Lee, Jonathan W|Kemel, Yelena|Vijai, Joseph|Mandelker, Diana|Zehir, Ahmet|Capanu, Marinela|Salo-Mullen, Erin|Arnold, Angela G|Yu, Kenneth H|Varghese, Anna M|Kelsen, David P|Brenner, Robin|Kaufmann, Erica|Ravic
PMID: 29506128
Journal: Oncotarget. 2018 Apr 13;9(28):19817-19825.
Title: Association between homologous recombination repair gene mutations and response to oxaliplatin in pancreatic cancer.
Author: Kondo, Tomohiro|Kanai, Masashi|Kou, Tadayuki|Sakuma, Tomohiro|Mochizuki, Hiroaki|Kamada, Mayumi|Nakatsui, Masahiko|Uza, Norimitsu|Kodama, Yuzo|Masui, Toshihiko|Takaori, Kyoichi|Matsumoto, Shigemi|Miyake, Hidehiko|Okuno, Yasushi|Muto, Manabu
PMID: 29731985
Journal: Theranostics. 2018 Apr 11;8(10):2782-2798.
Title: Plectin-targeted liposomes enhance the therapeutic efficacy of a PARP inhibitor in the treatment of ovarian cancer.
Author: Dasa, Siva Sai Krishna|Diakova, Galina|Suzuki, Ryo|Mills, Anne M|Gutknecht, Michael F|Klibanov, Alexander L|Slack-Davis, Jill K|Kelly, Kimberly A
PMID: 29774075
Journal: J Cancer Res Clin Oncol. 2018 Aug;144(8):1503-1507.
Title: Emerging strategies in BRCA-positive pancreatic cancer.
Author: Kowalewski, Adam|Szylberg, Lukasz|Saganek, Michal|Napiontek, Wojciech|Antosik, Paulina|Grzanka, Dariusz
PMID: 29777302
Journal: JAMA. 2018 Jun 19;319(23):2401-2409.
Title: Association Between Inherited Germline Mutations in Cancer Predisposition Genes and Risk of Pancreatic Cancer.
Author: Hu, Chunling|Hart, Steven N|Polley, Eric C|Gnanaolivu, Rohan|Shimelis, Hermela|Lee, Kun Y|Lilyquist, Jenna|Na, Jie|Moore, Raymond|Antwi, Samuel O|Bamlet, William R|Chaffee, Kari G|DiCarlo, John|Wu, Zhong|Samara, Raed|Kasi, Pashtoon M|McWilliams, Robert R|
PMID: 29922827
Journal: Arch Iran Med. 2018 Jun 1;21(6):228-233.
Title: Mutations in Known and Novel cancer Susceptibility Genes in Young Patients with Pancreatic Cancer.
Author: Alimirzaie, Sahar|Mohamadkhani, Ashraf|Masoudi, Sahar|Sellars, Erin|Boffetta, Paolo|Malekzadeh, Reza|Akbari, Mohammad R|Pourshams, Akram
PMID: 29940740
Journal: Clin Cancer Res. 2018 Jun 28. pii: 1078-0432.CCR-18-0531.
Title: Molecular Profiling of Patients with Pancreatic Cancer: Initial Results from the Know Your Tumor Initiative.
Author: Pishvaian, Michael J|Bender, Robert J|Halverson, David|Rahib, Lola|Hendifar, Andrew E|Mikhail, Sameh|Chung, Vincent|Picozzi, Vincent J|Sohal, Davendra|Blais, Edik M|Mason, Kimberly|Lyons, Emily E|Matrisian, Lynn M|Brody, Jonathan R|Madhavan, Subha|Petrico
PMID: 29954777
Journal: Genet Med. 2018 Jul 2. pii: 10.1038/s41436-018-0009-5.
Title: Germline cancer susceptibility gene variants, somatic second hits, and survival outcomes in patients with resected pancreatic cancer.
Author: Yurgelun, Matthew B|Chittenden, Anu B|Morales-Oyarvide, Vicente|Rubinson, Douglas A|Dunne, Richard F|Kozak, Margaret M|Qian, Zhi Rong|Welch, Marisa W|Brais, Lauren K|Da Silva, Annacarolina|Bui, Justin L|Yuan, Chen|Li, Tingting|Li, Wanwan|Masuda, Atsuhiro|
PMID: 29961768
Journal: JCO Precis Oncol. 2018;2018. Epub 2018 May 16.
Title: Rucaparib Monotherapy in Patients With Pancreatic Cancer and a Known Deleterious BRCA Mutation.
Author: Shroff, Rachna T|Hendifar, Andrew|McWilliams, Robert R|Geva, Ravit|Epelbaum, Ron|Rolfe, Lindsey|Goble, Sandra|Lin, Kevin K|Biankin, Andrew V|Giordano, Heidi|Vonderheide, Robert H|Domchek, Susan M
PMID: 30051098
Journal: Pancreas. 2018 Sep;47(8):924-936.
Title: Germline Variants and Risk for Pancreatic Cancer: A Systematic Review and Emerging Concepts.
Author: Zhan, Wei|Shelton, Celeste A|Greer, Phil J|Brand, Randall E|Whitcomb, David C
PMID: 30113427
Journal: Clin Cancer Res. 2018 Aug 21. pii: 1078-0432.CCR-18-1472.
Title: Germline and Somatic DNA Damage Repair Gene Mutations and Overall Survival in Metastatic Pancreatic Adenocarcinoma Patients Treated with FOLFIRINOX.
Author: Sehdev, Amikar|Gbolahan, Olumide|Hancock, Bradley A|Stanley, Melissa|Shahda, Safi|Wan, Jun|Wu, Howard H|Radovich, Milan|O'Neil, Bert H
PMID: 30131383
Journal: Gastrointest Endosc. 2018 Aug 23. pii: S0016-5107(18)32987-0.
Title: Chronic pancreatitis changes in high-risk individuals for pancreatic ductal adenocarcinoma.
Author: Thiruvengadam, Sushrut S|Chuang, Judith|Huang, Robert|Girotra, Mohit|Park, Walter G
PMID: 30145314
Journal: JCO Precis Oncol. 2018;2018. Epub 2018 Jan 19.
Title: Inference of Germline Mutational Status and Evaluation of Loss of Heterozygosity in High-Depth, Tumor-Only Sequencing Data.
Author: Khiabanian, Hossein|Hirshfield, Kim M|Goldfinger, Mendel|Bird, Simon|Stein, Mark|Aisner, Joseph|Toppmeyer, Deborah|Wong, Serena|Chan, Nancy|Dhar, Kalyani|Gheeya, Jinesh|Vig, Hetal|Hadigol, Mohammad|Pavlick, Dean|Ansari, Sepand|Ali, Siraj|Xia, Bing|Rodrigu
PMID: 30246169
Journal: Cancer Prev Res (Phila). 2018 Nov;11(11):679-686.
Title: High Prevalence of Hereditary Cancer Syndromes and Outcomes in Adults with Early-Onset Pancreatic Cancer.
Author: Bannon, Sarah A|Montiel, Maria F|Goldstein, Jennifer B|Dong, Wenli|Mork, Maureen E|Borras, Ester|Hasanov, Merve|Varadhachary, Gauri R|Maitra, Anirban|Katz, Matthew H|Feng, Lei|Futreal, Andrew|Fogelman, David R|Vilar, Eduardo|McAllister, Florencia
PMID: 30274973