Literatures

Primary Site >> Colorectal Cancer

Gene >> BRAF

1.
Journal:	Nature. 2002 Aug 29;418(6901):934.
Title:	Tumorigenesis: RAF/RAS oncogenes and mismatch-repair status.
Author:	Rajagopalan, Harith\|Bardelli, Alberto\|Lengauer, Christoph\|Kinzler, Kenneth W\|Vogelstein, Bert\|Velculescu, Victor E
PMID:	12198537

2.
Journal:	Cancer Res. 2002 Nov 15;62(22):6451-5.
Title:	Similarity of the phenotypic patterns associated with BRAF and KRAS mutations in colorectal neoplasia.
Author:	Yuen, Siu T\|Davies, Helen\|Chan, Tsun L\|Ho, Judy W\|Bignell, Graham R\|Cox, Charles\|Stephens, Philip\|Edkins, Sarah\|Tsui, Wendy W\|Chan, Annie S\|Futreal, P Andrew\|Stratton, Michael R\|Wooster, Richard\|Leung, Suet Y
PMID:	12438234

3.
Journal:	Cancer Res. 2003 Apr 1;63(7):1454-7.
Title:	High prevalence of BRAF mutations in thyroid cancer: genetic evidence for constitutive activation of the RET/PTC-RAS-BRAF signaling pathway in papillary thyroid carcinoma.
Author:	Kimura, Edna T\|Nikiforova, Marina N\|Zhu, Zhaowen\|Knauf, Jeffrey A\|Nikiforov, Yuri E\|Fagin, James A
PMID:	12670889

4.
Journal:	Biochim Biophys Acta. 2003 Jun 5;1653(1):25-40.
Title:	Raf proteins and cancer: B-Raf is identified as a mutational target.
Author:	Mercer, Kathryn E\|Pritchard, Catrin A
PMID:	12781369

5.
Journal:	Cancer Res. 2003 Aug 15;63(16):4878-81.
Title:	BRAF and KRAS mutations in colorectal hyperplastic polyps and serrated adenomas.
Author:	Chan, Tsun L\|Zhao, Wei\|Leung, Suet Y\|Yuen, Siu T
PMID:	12941809

6.
Journal:	Cancer Res. 2003 Sep 1;63(17):5209-12.
Title:	BRAF mutations in colon cancer are not likely attributable to defective DNA mismatch repair.
Author:	Wang, Liang\|Cunningham, Julie M\|Winters, Jennifer L\|Guenther, Jennifer C\|French, Amy J\|Boardman, Lisa A\|Burgart, Lawrence J\|McDonnell, Shannon K\|Schaid, Daniel J\|Thibodeau, Stephen N
PMID:	14500346

7.
Journal:	J Cell Sci. 2003 Dec 15;116(Pt 24):4957-63.
Title:	Elevated ERK-MAP kinase activity protects the FOS family member FRA-1 against proteasomal degradation in colon carcinoma cells.
Author:	Vial, Emmanuel\|Marshall, Christopher J
PMID:	14625389

8.
Journal:	Cancer Res. 2003 Nov 15;63(22):7595-9.
Title:	Carcinogenesis in MYH-associated polyposis follows a distinct genetic pathway.
Author:	Lipton, Lara\|Halford, Sarah E\|Johnson, Victoria\|Novelli, Marco R\|Jones, Angela\|Cummings, Carole\|Barclay, Ella\|Sieber, Oliver\|Sadat, Amir\|Bisgaard, Marie-Luise\|Hodgson, Shirley V\|Aaltonen, Lauri A\|Thomas, Huw J W\|Tomlinson, Ian P M
PMID:	14633673

9.
Journal:	Oncogene. 2003 Dec 11;22(57):9192-6.
Title:	BRAF mutations characterize colon but not gastric cancer with mismatch repair deficiency.
Author:	Oliveira, Carla\|Pinto, Mafalda\|Duval, Alex\|Brennetot, Caroline\|Domingo, Enric\|Espin, Eloi\|Armengol, Manel\|Yamamoto, Hiroyuki\|Hamelin, Richard\|Seruca, Raquel\|Schwartz, Simo Jr
PMID:	14668801

10.
Journal:	Cancer Res. 2003 Dec 1;63(23):8132-7.
Title:	Functional analysis of mutations within the kinase activation segment of B-Raf in human colorectal tumors.
Author:	Ikenoue, Tsuneo\|Hikiba, Yohko\|Kanai, Fumihiko\|Tanaka, Yasuo\|Imamura, Jun\|Imamura, Takaaki\|Ohta, Miki\|Ijichi, Hideaki\|Tateishi, Keisuke\|Kawakami, Takayuki\|Aragaki, Jun\|Matsumura, Masayuki\|Kawabe, Takao\|Omata, Masao
PMID:	14678966

11.
Journal:	Carcinogenesis. 2004 Apr;25(4):527-33. Epub 2003 Dec 19.
Title:	Mutation analysis of the BRAF, ARAF and RAF-1 genes in human colorectal adenocarcinomas.
Author:	Fransen, Karin\|Klintenas, Maria\|Osterstrom, Anna\|Dimberg, Jan\|Monstein, Hans-Jurg\|Soderkvist, Peter
PMID:	14688025

12.
Journal:	Genes Chromosomes Cancer. 2004 Feb;39(2):138-42.
Title:	Activated BRAF targets proximal colon tumors with mismatch repair deficiency and MLH1 inactivation.
Author:	Domingo, Enric\|Espin, Eloi\|Armengol, Manel\|Oliveira, Carla\|Pinto, Mafalda\|Duval, Alex\|Brennetot, Caroline\|Seruca, Raquel\|Hamelin, Richard\|Yamamoto, Hiroyuki\|Schwartz, Simo Jr
PMID:	14695993

13.
Journal:	Clin Cancer Res. 2004 Jan 1;10(1 Pt 1):191-5.
Title:	BRAF mutation is frequently present in sporadic colorectal cancer with methylated hMLH1, but not in hereditary nonpolyposis colorectal cancer.
Author:	Deng, Guoren\|Bell, Ian\|Crawley, Suzanne\|Gum, James\|Terdiman, Jonathan P\|Allen, Brian A\|Truta, Brindusa\|Sleisenger, Marvin H\|Kim, Young S
PMID:	14734469

14.
Journal:	Eur J Clin Invest. 2004 Feb;34(2):100-6.
Title:	K-ras and B-raf gene mutations are not associated with gastrin- and CCK2-receptor mRNA expression in human colorectal tumour tissues.
Author:	Monstein, H-J\|Fransen, K\|Dimberg, J\|Soderkvist, P
PMID:	14764072

15.
Journal:	J Pathol. 2004 Mar;202(3):336-40.
Title:	In ovarian neoplasms, BRAF, but not KRAS, mutations are restricted to low-grade serous tumours.
Author:	Sieben, Nathalie L G\|Macropoulos, Patricia\|Roemen, Guido M J M\|Kolkman-Uljee, Sandra M\|Jan Fleuren, Gert\|Houmadi, Rifat\|Diss, Tim\|Warren, Bretta\|Al Adnani, Mudher\|De Goeij, Anton P M\|Krausz, Thomas\|Flanagan, Adrienne M
PMID:	14991899

16.
Journal:	Cancer Res. 2004 Apr 1;64(7):2544-51.
Title:	Inverse PCR-based RFLP scanning identifies low-level mutation signatures in colon cells and tumors.
Author:	Liu, Wei-Hua\|Kaur, Manjit\|Wang, Gang\|Zhu, Penny\|Zhang, Yuzhi\|Makrigiorgos, G Mike
PMID:	15059910

17.
Journal:	Cancer Genet Cytogenet. 2004 Feb;149(1):68-71.
Title:	Rapid detection of mutations in the BRAF gene using real-time polymerase chain reaction and melting curve analysis.
Author:	Ikenoue, Tsuneo\|Hikiba, Yohko\|Kanai, Fumihiko\|Ijichi, Hideaki\|Togo, Goichi\|Ohta, Miki\|Watabe, Hirotsugu\|Yamaji, Yutaka\|Okamoto, Makoto\|Aragaki, Jun\|Matsumura, Masayuki\|Kawabe, Takao\|Omata, Masao
PMID:	15104286

18.
Journal:	Am J Obstet Gynecol. 2004 Apr;190(4):935-42.
Title:	RAS/RAF mutation and defective DNA mismatch repair in endometrial cancers.
Author:	Mutch, David G\|Powell, Matthew A\|Mallon, Mary Ann\|Goodfellow, Paul J
PMID:	15118616

19.
Journal:	Cancer Res. 2004 May 15;64(10):3428-35.
Title:	Different effects of point mutations within the B-Raf glycine-rich loop in colorectal tumors on mitogen-activated protein/extracellular signal-regulated kinase kinase/extracellular signal-regulated kinase and nuclear factor kappaB pathway and cellular tra
Author:	Ikenoue, Tsuneo\|Hikiba, Yohko\|Kanai, Fumihiko\|Aragaki, Jun\|Tanaka, Yasuo\|Imamura, Jun\|Imamura, Takaaki\|Ohta, Miki\|Ijichi, Hideaki\|Tateishi, Keisuke\|Kawakami, Takayuki\|Matsumura, Masayuki\|Kawabe, Takao\|Omata, Masao
PMID:	15150094

20.
Journal:	Cancer Lett. 2004 Jul 28;211(1):105-9.
Title:	Both BRAF and KRAS mutations are rare in colorectal carcinomas from patients with hereditary nonpolyposis colorectal cancer.
Author:	Miyaki, Michiko\|Iijima, Takeru\|Yamaguchi, Tatsuro\|Kadofuku, Tsuyoki\|Funata, Nobuaki\|Mori, Takeo
PMID:	15194222

21.
Journal:	J Clin Pathol. 2004 Jul;57(7):682-6.
Title:	My approach to serrated polyps of the colorectum.
Author:	Higuchi, T\|Jass, J R
PMID:	15220357

22.
Journal:	Ann N Y Acad Sci. 2004 Jun;1022:250-6.
Title:	High sensitivity scanning of colorectal tumors and matched plasma DNA for mutations in APC, TP53, K-RAS, and BRAF genes with a novel DHPLC fluorescence detection platform.
Author:	Lilleberg, S L\|Durocher, J\|Sanders, C\|Walters, K\|Culver, K
PMID:	15251969

23.
Journal:	Mol Cell Probes. 2004 Oct;18(5):349-52.
Title:	Real-time allele-specific amplification for sensitive detection of the BRAF mutation V600E.
Author:	Jarry, Anne\|Masson, Damien\|Cassagnau, Elisabeth\|Parois, Sigrid\|Laboisse, Christian\|Denis, Marc G
PMID:	15294323

24.
Journal:	Fam Cancer. 2004;3(2):93-100.
Title:	HNPCC and sporadic MSI-H colorectal cancer: a review of the morphological similarities and differences.
Author:	Jass, Jeremy R
PMID:	15340259

25.
Journal:	Fam Cancer. 2004;3(2):101-7.
Title:	Promoter hypermethylation frequency and BRAF mutations distinguish hereditary non-polyposis colon cancer from sporadic MSI-H colon cancer.
Author:	McGivern, A\|Wynter, C V A\|Whitehall, V L J\|Kambara, T\|Spring, K J\|Walsh, M D\|Barker, M A\|Arnold, S\|Simms, L A\|Leggett, B A\|Young, J\|Jass, J R
PMID:	15340260

26.
Journal:	J Med Genet. 2004 Sep;41(9):664-8.
Title:	BRAF screening as a low-cost effective strategy for simplifying HNPCC genetic testing.
Author:	Domingo, E\|Laiho, P\|Ollikainen, M\|Pinto, M\|Wang, L\|French, A J\|Westra, J\|Frebourg, T\|Espin, E\|Armengol, M\|Hamelin, R\|Yamamoto, H\|Hofstra, R M W\|Seruca, R\|Lindblom, A\|Peltomaki, P\|Thibodeau, S N\|Aaltonen, L A\|Schwartz, S Jr
PMID:	15342696

27.
Journal:	Hum Genet. 2004 Nov;115(6):498-503. Epub 2004 Sep 24.
Title:	Mutational analysis of OGG1, MYH, MTH1 in FAP, HNPCC and sporadic colorectal cancer patients: R154H OGG1 polymorphism is associated with sporadic colorectal cancer patients.
Author:	Kim, I-J\|Ku, J-L\|Kang, H C\|Park, J-H\|Yoon, K-A\|Shin, Y\|Park, H-W\|Jang, S G\|Lim, S-K\|Han, S Y\|Shin, Y-K\|Lee, M R\|Jeong, S-Y\|Shin, H-R\|Lee, J S\|Kim, W-H\|Park, J-G
PMID:	15449173

28.
Journal:	Am J Surg Pathol. 2004 Nov;28(11):1452-9.
Title:	BRAF and KRAS Mutations in hyperplastic polyps and serrated adenomas of the colorectum: relationship to histology and CpG island methylation status.
Author:	Yang, Shi\|Farraye, Francis A\|Mack, Charline\|Posnik, Oksana\|O'Brien, Michael J
PMID:	15489648

29.
Journal:	Scand J Gastroenterol. 2004 Aug;39(8):748-53.
Title:	Mutational activation of the RAS-RAF-MAPK and the Wnt pathway in small intestinal adenocarcinomas.
Author:	Blaker, H\|Helmchen, B\|Bonisch, A\|Aulmann, S\|Penzel, R\|Otto, H F\|Rieker, R J
PMID:	15513360

30.
Journal:	J Clin Oncol. 2004 Nov 15;22(22):4584-94.
Title:	Colorectal cancer with mutation in BRAF, KRAS, and wild-type with respect to both oncogenes showing different patterns of DNA methylation.
Author:	Nagasaka, Takeshi\|Sasamoto, Hiromi\|Notohara, Kenji\|Cullings, Harry M\|Takeda, Masanori\|Kimura, Keigo\|Kambara, Takeshi\|MacPhee, Donald G\|Young, Joanne\|Leggett, Barbara A\|Jass, Jeremy R\|Tanaka, Noriaki\|Matsubara, Nagahide
PMID:	15542810

31.
Journal:	APMIS. 2005 Jan;113(1):54-7.
Title:	Mutational analysis of the ARAF gene in human cancers.
Author:	Lee, Jong Woo\|Soung, Young Hwa\|Kim, Su Young\|Park, Won Sang\|Nam, Suk Woo\|Min, Woo Sung\|Kim, Sang Ho\|Lee, Jung Young\|Yoo, Nam Jin\|Lee, Sug Hyung
PMID:	15676015

32.
Journal:	J Cell Physiol. 2005 Aug;204(2):484-8.
Title:	Mutation analysis of p53, K-ras, and BRAF genes in colorectal cancer progression.
Author:	Calistri, Daniele\|Rengucci, Claudia\|Seymour, Ian\|Lattuneddu, Arturo\|Polifemo, Anna Maria\|Monti, Franco\|Saragoni, Luca\|Amadori, Dino
PMID:	15702478

33.
Journal:	Int J Cancer. 2005 Jul 10;115(5):673-7.
Title:	Mutations of the BRAF gene in ulcerative colitis-related colorectal carcinoma.
Author:	Aust, Daniela E\|Haase, Michael\|Dobryden, Lyudmyla\|Markwarth, Annett\|Lohrs, Udo\|Wittekind, Christian\|Baretton, Gustavo B\|Tannapfel, Andrea
PMID:	15704157

34.
Journal:	Int J Cancer. 2005 Jul 20;115(6):943-50.
Title:	BRAF mutation associated with dysregulation of apoptosis in human colorectal neoplasms.
Author:	Ikehara, Nobunao\|Semba, Shuho\|Sakashita, Masanori\|Aoyama, Nobuo\|Kasuga, Masato\|Yokozaki, Hiroshi
PMID:	15729718

35.
Journal:	Clin Gastroenterol Hepatol. 2005 Mar;3(3):254-63.
Title:	Evidence for BRAF mutation and variable levels of microsatellite instability in a syndrome of familial colorectal cancer.
Author:	Young, Joanne\|Barker, Melissa A\|Simms, Lisa A\|Walsh, Michael D\|Biden, Kelli G\|Buchanan, Daniel\|Buttenshaw, Ron\|Whitehall, Vicki L J\|Arnold, Sven\|Jackson, Leigh\|Kambara, Takeshi\|Spring, Kevin J\|Jenkins, Mark A\|Walker, Graeme J\|Hopper, John L\|Leggett, Barba
PMID:	15765445

36.
Journal:	Carcinogenesis. 2005 Jul;26(7):1207-14.
Title:	Transformation of immortalized colorectal crypt cells by microcystin involving constitutive activation of Akt and MAPK cascade.
Author:	Zhu, Yongliang\|Zhong, Xian\|Zheng, Shu\|Ge, Zhen\|Du, Qin\|Zhang, Suzhang
PMID:	15774489

37.
Journal:	Oncogene. 2005 Jun 2;24(24):3995-8.
Title:	BRAF-V600E is not involved in the colorectal tumorigenesis of HNPCC in patients with functional MLH1 and MSH2 genes.
Author:	Domingo, Enric\|Niessen, Renee C\|Oliveira, Carla\|Alhopuro, Pia\|Moutinho, Catia\|Espin, Eloi\|Armengol, Manel\|Sijmons, Rolf H\|Kleibeuker, Jan H\|Seruca, Raquel\|Aaltonen, Lauri A\|Imai, Kohzoh\|Yamamoto, Hiroyuki\|Schwartz, Simo Jr\|Hofstra, Robert M W
PMID:	15782118

38.
Journal:	Am J Pathol. 2005 Apr;166(4):1069-75.
Title:	BRAF mutations in aberrant crypt foci and hyperplastic polyposis.
Author:	Beach, Robyn\|Chan, Annie On-On\|Wu, Tsung-Teh\|White, Jill A\|Morris, Jeffrey S\|Lunagomez, Simon\|Broaddus, Russell R\|Issa, Jean-Pierre J\|Hamilton, Stanley R\|Rashid, Asif
PMID:	15793287

39.
Journal:	Cancer Chemother Pharmacol. 2005 Aug;56(2):126-37.
Title:	Comparison of 17-dimethylaminoethylamino-17-demethoxy-geldanamycin (17DMAG) and 17-allylamino-17-demethoxygeldanamycin (17AAG) in vitro: effects on Hsp90 and client proteins in melanoma models.
Author:	Smith, Victoria\|Sausville, Edward A\|Camalier, Richard F\|Fiebig, Heinz-Herbert\|Burger, Angelika M
PMID:	15841378

40.
Journal:	Lancet Oncol. 2005 May;6(5):279-86.
Title:	Gene copy number for epidermal growth factor receptor (EGFR) and clinical response to antiEGFR treatment in colorectal cancer: a cohort study.
Author:	Moroni, Mauro\|Veronese, Silvio\|Benvenuti, Silvia\|Marrapese, Giovanna\|Sartore-Bianchi, Andrea\|Di Nicolantonio, Federica\|Gambacorta, Marcello\|Siena, Salvatore\|Bardelli, Alberto
PMID:	15863375

41.
Journal:	Eur J Cancer. 2005 Jul;41(11):1649-54.
Title:	The prevalence of PIK3CA mutations in gastric and colon cancer.
Author:	Velho, Sergia\|Oliveira, Carla\|Ferreira, Ana\|Ferreira, Antonio Carlos\|Suriano, Gianpaolo\|Schwartz, Simo Jr\|Duval, Alex\|Carneiro, Fatima\|Machado, Jose Carlos\|Hamelin, Richard\|Seruca, Raquel
PMID:	15994075

42.
Journal:	Oncogene. 2005 Nov 17;24(51):7630-4.
Title:	Concomitant RASSF1A hypermethylation and KRAS/BRAF mutations occur preferentially in MSI sporadic colorectal cancer.
Author:	Oliveira, Carla\|Velho, Sergia\|Domingo, Enric\|Preto, Ana\|Hofstra, Robert M W\|Hamelin, Richard\|Yamamoto, Hiroyuki\|Seruca, Raquel\|Schwartz, Simo Jr
PMID:	16007118

43.
Journal:	Gastroenterology. 2005 Jul;129(1):156-69.
Title:	The Ras effector RASSF2 is a novel tumor-suppressor gene in human colorectal cancer.
Author:	Akino, Kimishige\|Toyota, Minoru\|Suzuki, Hiromu\|Mita, Hiroaki\|Sasaki, Yasushi\|Ohe-Toyota, Mutsumi\|Issa, Jean-Pierre J\|Hinoda, Yuji\|Imai, Kohzoh\|Tokino, Takashi
PMID:	16012945

44.
Journal:	Cancer. 2005 Sep 1;104(5):952-61.
Title:	BRAF mutations in colorectal carcinoma suggest two entities of microsatellite-unstable tumors.
Author:	Lubomierski, Nikolaus\|Plotz, Guido\|Wormek, Marc\|Engels, Knut\|Kriener, Susanne\|Trojan, Jorg\|Jungling, Bernd\|Zeuzem, Stefan\|Raedle, Jochen
PMID:	16015629

45.
Journal:	Cancer Res. 2005 Jul 15;65(14):6063-9.
Title:	Poor survival associated with the BRAF V600E mutation in microsatellite-stable colon cancers.
Author:	Samowitz, Wade S\|Sweeney, Carol\|Herrick, Jennifer\|Albertsen, Hans\|Levin, Theodore R\|Murtaugh, Maureen A\|Wolff, Roger K\|Slattery, Martha L
PMID:	16024606

46.
Journal:	Gastroenterology. 2005 Sep;129(3):837-45.
Title:	Evaluation of a large, population-based sample supports a CpG island methylator phenotype in colon cancer.
Author:	Samowitz, Wade S\|Albertsen, Hans\|Herrick, Jennifer\|Levin, Theodore R\|Sweeney, Carol\|Murtaugh, Maureen A\|Wolff, Roger K\|Slattery, Martha L
PMID:	16143123

47.
Journal:	Clin Cancer Res. 2005 Sep 15;11(18):6650-6.
Title:	Molecular alterations in tumors and response to combination chemotherapy with gefitinib for advanced colorectal cancer.
Author:	Ogino, Shuji\|Meyerhardt, Jeffrey A\|Cantor, Mami\|Brahmandam, Mohan\|Clark, Jeffrey W\|Namgyal, Chungdak\|Kawasaki, Takako\|Kinsella, Kate\|Michelini, Ann L\|Enzinger, Peter C\|Kulke, Matthew H\|Ryan, David P\|Loda, Massimo\|Fuchs, Charles S
PMID:	16166444

48.
Journal:	Mod Pathol. 2006 Jan;19(1):59-68.
Title:	Distinct molecular features of colorectal carcinoma with signet ring cell component and colorectal carcinoma with mucinous component.
Author:	Ogino, Shuji\|Brahmandam, Mohan\|Cantor, Mami\|Namgyal, Chungdak\|Kawasaki, Takako\|Kirkner, Gregory\|Meyerhardt, Jeffrey A\|Loda, Massimo\|Fuchs, Charles S
PMID:	16118624

49.
Journal:	Int J Cancer. 2006 Mar 15;118(6):1426-9.
Title:	Somatic mutations of the ERBB4 kinase domain in human cancers.
Author:	Soung, Young Hwa\|Lee, Jong Woo\|Kim, Su Young\|Wang, Young Pil\|Jo, Keon Hyun\|Moon, Seok Whan\|Park, Won Sang\|Nam, Suk Woo\|Lee, Jung Young\|Yoo, Nam Jin\|Lee, Sug Hyung
PMID:	16187281

50.
Journal:	Carcinogenesis. 2006 Mar;27(3):392-404. Epub 2005 Oct 11.
Title:	Oligonucleotide microarray analysis of distinct gene expression patterns in colorectal cancer tissues harboring BRAF and K-ras mutations.
Author:	Kim, Il-Jin\|Kang, Hio Chung\|Jang, Sang-Geun\|Kim, Kun\|Ahn, Sun-A\|Yoon, Hyun-Ju\|Yoon, Sang Nam\|Park, Jae-Gahb
PMID:	16219636

51.
Journal:	Int J Cancer. 2006 Apr 1;118(7):1721-7.
Title:	Relationship between genetic alterations and prognosis in sporadic colorectal cancer.
Author:	Chang, Shih-Ching\|Lin, Jen-Kou\|Yang, Shung Haur\|Wang, Huann-Sheng\|Li, Anna Fen-Yau\|Chi, Chin-Wen
PMID:	16231316

52.
Journal:	Biochem Biophys Res Commun. 2006 Feb 10;340(2):469-75. Epub 2005 Dec 15.
Title:	Correlation of PIK3Ca mutations with gene expression and drug sensitivity in NCI-60 cell lines.
Author:	Whyte, David B\|Holbeck, Susan L
PMID:	16376301

53.
Journal:	Int J Cancer. 2006 Jun 1;118(11):2765-71.
Title:	BRAF mutation, CpG island methylator phenotype and microsatellite instability occur more frequently and concordantly in mucinous than non-mucinous colorectal cancer.
Author:	Tanaka, Hirofumi\|Deng, Guoren\|Matsuzaki, Koji\|Kakar, Sanjay\|Kim, Grace E\|Miura, Soichiro\|Sleisenger, Marvin H\|Kim, Young S
PMID:	16381005

54.
Journal:	Clin Cancer Res. 2006 Jan 1;12(1):57-61.
Title:	Somatic mutations of ERBB2 kinase domain in gastric, colorectal, and breast carcinomas.
Author:	Lee, Jong Woo\|Soung, Young Hwa\|Seo, Si Hyung\|Kim, Su Young\|Park, Cho Hyun\|Wang, Young Pil\|Park, Kyeongmee\|Nam, Suk Woo\|Park, Won Sang\|Kim, Sang Ho\|Lee, Jung Young\|Yoo, Nam Jin\|Lee, Sug Hyung
PMID:	16397024

55.
Journal:	Mol Cancer. 2006 Jan 10;5:2.
Title:	BRAF mutations are associated with distinctive clinical, pathological and molecular features of colorectal cancer independently of microsatellite instability status.
Author:	Li, Wei Qi\|Kawakami, Kazuyuki\|Ruszkiewicz, Andrew\|Bennett, Graeme\|Moore, James\|Iacopetta, Barry
PMID:	16403224

56.
Journal:	Gut. 2006 Jul;55(7):1000-6. Epub 2006 Jan 11.
Title:	CpG island methylator phenotype (CIMP) of colorectal cancer is best characterised by quantitative DNA methylation analysis and prospective cohort studies.
Author:	Ogino, S\|Cantor, M\|Kawasaki, T\|Brahmandam, M\|Kirkner, G J\|Weisenberger, D J\|Campan, M\|Laird, P W\|Loda, M\|Fuchs, C S
PMID:	16407376

57.
Journal:	Eur Urol. 2006 Nov;50(5):1102-9; discussion 1109-10.
Title:	Mitogen-activated protein kinase signaling is activated in prostate tumors but not mediated by B-RAF mutations.
Author:	Burger, Maximilian\|Denzinger, Stefan\|Hammerschmied, Christine\|Tannapfel, Andrea\|Maderstorfer, Armin\|Wieland, Wolf Ferdinand\|Hartmann, Arndt\|Stoehr, Robert
PMID:	16413100

58.
Journal:	Anticancer Res. 2006 Jan-Feb;26(1A):107-19.
Title:	Aberrant crypt foci.
Author:	Alrawi, Sadir J\|Schiff, Michael\|Carroll, Robert E\|Dayton, Merril\|Gibbs, John F\|Kulavlat, Mahmood\|Tan, Dongfeng\|Berman, Kevin\|Stoler, Daniel L\|Anderson, Garth R
PMID:	16475686

59.
Journal:	Cancer Res. 2006 Apr 15;66(8):3992-5.
Title:	KRAS mutation status is predictive of response to cetuximab therapy in colorectal cancer.
Author:	Lievre, Astrid\|Bachet, Jean-Baptiste\|Le Corre, Delphine\|Boige, Valerie\|Landi, Bruno\|Emile, Jean-Francois\|Cote, Jean-Francois\|Tomasic, Gorana\|Penna, Christophe\|Ducreux, Michel\|Rougier, Philippe\|Penault-Llorca, Frederique\|Laurent-Puig, Pierre
PMID:	16618717

60.
Journal:	Anticancer Res. 2006 Mar-Apr;26(2A):1077-84.
Title:	Cancer genetics of sporadic colorectal cancer: BRAF and PI3KCA mutations, their impact on signaling and novel targeted therapies.
Author:	Oikonomou, Eftychia\|Pintzas, Alexandros
PMID:	16619509

61.
Journal:	Cancer. 2006 Jun 1;106(11):2528-9; author reply 2529.
Title:	BRAF mutations in colorectal carcinoma suggest two entities of microsatellite-unstable tumors.
Author:	Vilar, Eduardo\|Balmana, Judith\|Espin, Eloy
PMID:	16628650

62.
Journal:	Mod Pathol. 2006 Aug;19(8):1083-90.
Title:	Epigenetic profiling of synchronous colorectal neoplasias by quantitative DNA methylation analysis.
Author:	Ogino, Shuji\|Brahmandam, Mohan\|Kawasaki, Takako\|Kirkner, Gregory J\|Loda, Massimo\|Fuchs, Charles S
PMID:	16699497

63.
Journal:	Cancer Res. 2006 Jun 1;66(11):5656-64.
Title:	Epidermal growth factor receptor signaling is up-regulated in human colonic aberrant crypt foci.
Author:	Cohen, Greg\|Mustafi, Reba\|Chumsangsri, Anusara\|Little, Nathaniel\|Nathanson, Jeff\|Cerda, Sonia\|Jagadeeswaran, Sujatha\|Dougherty, Urszula\|Joseph, Loren\|Hart, John\|Yerian, Lisa\|Tretiakova, Maria\|Yuan, Weihua\|Obara, Piotr\|Khare, Sharad\|Sinicrope, Frank A\|Fich
PMID:	16740703

64.
Journal:	Nat Genet. 2006 Jul;38(7):787-93. Epub 2006 Jun 25.
Title:	CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer.
Author:	Weisenberger, Daniel J\|Siegmund, Kimberly D\|Campan, Mihaela\|Young, Joanne\|Long, Tiffany I\|Faasse, Mark A\|Kang, Gyeong Hoon\|Widschwendter, Martin\|Weener, Deborah\|Buchanan, Daniel\|Koh, Hoey\|Simms, Lisa\|Barker, Melissa\|Leggett, Barbara\|Levine, Joan\|Kim, Myun
PMID:	16804544

65.
Journal:	J Pathol. 2006 Oct;210(2):147-54.
Title:	Down-regulation of p21 (CDKN1A/CIP1) is inversely associated with microsatellite instability and CpG island methylator phenotype (CIMP) in colorectal cancer.
Author:	Ogino, S\|Kawasaki, T\|Kirkner, G J\|Ogawa, A\|Dorfman, I\|Loda, M\|Fuchs, C S
PMID:	16850502

66.
Journal:	Histopathology. 2006 Aug;49(2):121-31.
Title:	Advanced colorectal polyps with the molecular and morphological features of serrated polyps and adenomas: concept of a 'fusion' pathway to colorectal cancer.
Author:	Jass, J R\|Baker, K\|Zlobec, I\|Higuchi, T\|Barker, M\|Buchanan, D\|Young, J
PMID:	16879389

67.
Journal:	Head Neck. 2006 Oct;28(10):909-15.
Title:	Phenotype-genotype correlation: challenge of intestinal-type adenocarcinoma of the nasal cavity and paranasal sinuses.
Author:	Frattini, Milo\|Perrone, Federica\|Suardi, Simona\|Balestra, Debora\|Caramuta, Stefano\|Colombo, Federica\|Licitra, Lisa\|Cantu, Giulio\|Pierotti, Marco A\|Pilotti, Silvana
PMID:	16906516

68.
Journal:	J Exp Clin Cancer Res. 2006 Jun;25(2):235-42.
Title:	Frequent involvement of ras-signalling pathways in both polypoid-type and flat-type early-stage colorectal cancers.
Author:	Noda, H\|Kato, Y\|Yoshikawa, H\|Arai, M\|Togashi, K\|Nagai, H\|Konishi, F\|Miki, Y
PMID:	16918136

69.
Journal:	Br J Cancer. 2006 Oct 23;95(8):1101-7.
Title:	Genetic and epigenetic changes in primary metastatic and nonmetastatic colorectal cancer.
Author:	Miranda, E\|Destro, A\|Malesci, A\|Balladore, E\|Bianchi, P\|Baryshnikova, E\|Franchi, G\|Morenghi, E\|Laghi, L\|Gennari, L\|Roncalli, M
PMID:	16969349

70.
Journal:	Int J Cancer. 2006 Nov 15;119(10):2272-8.
Title:	APC gene methylation is inversely correlated with features of the CpG island methylator phenotype in colorectal cancer.
Author:	Iacopetta, Barry\|Grieu, Fabienne\|Li, Wei\|Ruszkiewicz, Andrew\|Caruso, Maria\|Moore, James\|Watanabe, Goh\|Kawakami, Kazuyuki
PMID:	16981189

71.
Journal:	Cell Oncol. 2006;28(4):161-6.
Title:	KRAS, p53 and BRAF gene mutations and aneuploidy in sporadic colorectal cancer progression.
Author:	Calistri, Daniele\|Rengucci, Claudia\|Seymour, Ian\|Leonardi, Elena\|Truini, Mauro\|Malacarne, Davide\|Castagnola, Patrizio\|Giaretti, Walter
PMID:	16988471

72.
Journal:	Cancer Epidemiol Biomarkers Prev. 2006 Oct;15(10):1778-84.
Title:	The case for a genetic predisposition to serrated neoplasia in the colorectum: hypothesis and review of the literature.
Author:	Young, Joanne\|Jass, Jeremy R
PMID:	17035382

73.
Journal:	J Mol Diagn. 2006 Nov;8(5):540-3.
Title:	Detection of BRAF V600E mutation in colorectal cancer: comparison of automatic sequencing and real-time chemistry methodology.
Author:	Benlloch, Susana\|Paya, Artemio\|Alenda, Cristina\|Bessa, Xavier\|Andreu, Montserrat\|Jover, Rodrigo\|Castells, Antoni\|Llor, Xavier\|Aranda, F Ignacio\|Massuti, Bartomeu
PMID:	17065421

74.
Journal:	J Mol Diagn. 2006 Nov;8(5):582-8.
Title:	CpG island methylator phenotype-low (CIMP-low) in colorectal cancer: possible associations with male sex and KRAS mutations.
Author:	Ogino, Shuji\|Kawasaki, Takako\|Kirkner, Gregory J\|Loda, Massimo\|Fuchs, Charles S
PMID:	17065427

75.
Journal:	Clin Chem. 2006 Dec;52(12):2299-302.
Title:	Improved marker combination for detection of de novo genetic variation and aberrant DNA in colorectal neoplasia.
Author:	Kann, Lisa\|Han, James\|Ahlquist, David\|Levin, Theodore\|Rex, Douglas\|Whitney, Duncan\|Markowitz, Sanford\|Shuber, Anthony
PMID:	17082247

76.
Journal:	Gastroenterology. 2006 Nov;131(5):1400-7. Epub 2006 Aug 18.
Title:	High prevalence of sessile serrated adenomas with BRAF mutations: a prospective study of patients undergoing colonoscopy.
Author:	Spring, Kevin J\|Zhao, Zhen Zhen\|Karamatic, Rozemary\|Walsh, Michael D\|Whitehall, Vicki L J\|Pike, Tanya\|Simms, Lisa A\|Young, Joanne\|James, Michael\|Montgomery, Grant W\|Appleyard, Mark\|Hewett, David\|Togashi, Kazutomo\|Jass, Jeremy R\|Leggett, Barbara A
PMID:	17101316

77.
Journal:	Cancer Epidemiol Biomarkers Prev. 2006 Nov;15(11):2270-3.
Title:	Somatic BRAF-V600E mutations in familial colorectal cancer.
Author:	Vandrovcova, Jana\|Lagerstedt-Robinsson, Kristina\|Pahlman, Lars\|Lindblom, Annika
PMID:	17119056

78.
Journal:	Am J Surg Pathol. 2006 Dec;30(12):1491-501.
Title:	Comparison of microsatellite instability, CpG island methylation phenotype, BRAF and KRAS status in serrated polyps and traditional adenomas indicates separate pathways to distinct colorectal carcinoma end points.
Author:	O'Brien, Michael J\|Yang, Shi\|Mack, Charline\|Xu, Huihong\|Huang, Christopher S\|Mulcahy, Elizabeth\|Amorosino, Mark\|Farraye, Francis A
PMID:	17122504

79.
Journal:	J Natl Cancer Inst. 2006 Dec 6;98(23):1731-8.
Title:	Association of smoking, CpG island methylator phenotype, and V600E BRAF mutations in colon cancer.
Author:	Samowitz, Wade S\|Albertsen, Hans\|Sweeney, Carol\|Herrick, Jennifer\|Caan, Bette J\|Anderson, Kristin E\|Wolff, Roger K\|Slattery, Martha L
PMID:	17148775

80.
Journal:	Cancer Biomark. 2006;2(1-2):37-49.
Title:	New aspects in molecular diagnosis of Lynch syndrome (HNPCC).
Author:	Fridrichova, Ivana
PMID:	17192058

81.
Journal:	Endocr Regul. 2006 Dec;40(4):129-38.
Title:	BRAF mutations in papillary thyroid carcinoma.
Author:	Wojciechowska, Katarzyna\|Lewinski, Andrzej
PMID:	17201587

82.
Journal:	Crit Rev Oncog. 2006 Dec;12(3-4):273-87.
Title:	Colorectal cancer: a multipathway disease.
Author:	Jass, Jeremy R
PMID:	17425506

83.
Journal:	Verh Dtsch Ges Pathol. 2006;90:18-24.
Title:	Types of colorectal adenoma.
Author:	Lugli, A\|Jass, J R
PMID:	17867575

84.
Journal:	Verh Dtsch Ges Pathol. 2006;90:236-43.
Title:	[A new quantitative DNA-methylation analysis of MSI colorectal cancers helps to separate sporadic colorectal cancers from HNPCC-candidates].
Author:	Bettstetter, M\|Rummele, P\|Hofstadter, F\|Dietmaier, W
PMID:	17867602

85.
Journal:	Oncogene. 2007 Jan 4;26(1):158-63. Epub 2006 Sep 4.
Title:	KRAS and BRAF oncogenic mutations in MSS colorectal carcinoma progression.
Author:	Oliveira, C\|Velho, S\|Moutinho, C\|Ferreira, A\|Preto, A\|Domingo, E\|Capelinha, A F\|Duval, A\|Hamelin, R\|Machado, J C\|Schwartz, S Jr\|Carneiro, F\|Seruca, R
PMID:	16953233

86.
Journal:	Int J Cancer. 2007 Jan 1;120(1):7-12.
Title:	Correlation between hypermethylation of the RASSF2A promoter and K-ras/BRAF mutations in microsatellite-stable colorectal cancers.
Author:	Park, Hye-Won\|Kang, Hio Chung\|Kim, Il-Jin\|Jang, Sang-Geun\|Kim, Kun\|Yoon, Hyun-Ju\|Jeong, Seung-Yong\|Park, Jae-Gahb
PMID:	17013898

87.
Journal:	Mod Pathol. 2007 Jan;20(1):15-22. Epub 2006 Nov 3.
Title:	Loss of nuclear p27 (CDKN1B/KIP1) in colorectal cancer is correlated with microsatellite instability and CIMP.
Author:	Ogino, Shuji\|Kawasaki, Takako\|Kirkner, Gregory J\|Yamaji, Taiki\|Loda, Massimo\|Fuchs, Charles S
PMID:	17086168

88.
Journal:	Gastroenterology. 2007 Jan;132(1):127-38.
Title:	The CpG island methylator phenotype and chromosomal instability are inversely correlated in sporadic colorectal cancer.
Author:	Goel, Ajay\|Nagasaka, Takeshi\|Arnold, Christian N\|Inoue, Toru\|Hamilton, Cody\|Niedzwiecki, Donna\|Compton, Carolyn\|Mayer, Robert J\|Goldberg, Richard\|Bertagnolli, Monica M\|Boland, C Richard
PMID:	17087942

89.
Journal:	Int J Cancer. 2007 Feb 1;120(3):656-63.
Title:	Diet and lifestyle factor associations with CpG island methylator phenotype and BRAF mutations in colon cancer.
Author:	Slattery, Martha L\|Curtin, Karen\|Sweeney, Carol\|Levin, Theodore R\|Potter, John\|Wolff, Roger K\|Albertsen, Hans\|Samowitz, Wade S
PMID:	17096326

90.
Journal:	Ann Surg Oncol. 2007 Mar;14(3):1229-36. Epub 2006 Dec 31.
Title:	Role of the BRAF mutations in the microsatellite instability genetic pathway in sporadic colorectal cancer.
Author:	Maestro, M L\|Vidaurreta, M\|Sanz-Casla, M T\|Rafael, S\|Veganzones, S\|Martinez, A\|Aguilera, C\|Herranz, M D\|Cerdan, J\|Arroyo, M
PMID:	17195912

91.
Journal:	Histopathology. 2007 Jan;50(1):113-30.
Title:	Classification of colorectal cancer based on correlation of clinical, morphological and molecular features.
Author:	Jass, J R
PMID:	17204026

92.
Journal:	Histopathology. 2007 Jan;50(1):131-50.
Title:	Colorectal serrated adenocarcinoma.
Author:	Makinen, M J
PMID:	17204027

93.
Journal:	Hum Pathol. 2007 Apr;38(4):585-92. Epub 2007 Jan 19.
Title:	Cytoplasmic localization of p27 (cyclin-dependent kinase inhibitor 1B/KIP1) in colorectal cancer: inverse correlations with nuclear p27 loss, microsatellite instability, and CpG island methylator phenotype.
Author:	Ogino, Shuji\|Kawasaki, Takako\|Ogawa, Akiyo\|Kirkner, Gregory J\|Loda, Massimo\|Fuchs, Charles S
PMID:	17239930

94.
Journal:	J Mol Diagn. 2007 Feb;9(1):55-63.
Title:	Development and applications of a BRAF oligonucleotide microarray.
Author:	Kim, Il-Jin\|Kang, Hio Chung\|Jang, Sang Geun\|Ahn, Sun-A\|Yoon, Hyun-Ju\|Park, Jae-Gahb
PMID:	17251336

95.
Journal:	Gastroenterology. 2007 Feb;132(2):527-30. Epub 2006 Nov 29.
Title:	Homozygous PMS2 deletion causes a severe colorectal cancer and multiple adenoma phenotype without extraintestinal cancer.
Author:	Will, Olivia\|Carvajal-Carmona, Luis G\|Gorman, Patricia\|Howarth, Kimberley M\|Jones, Angela M\|Polanco-Echeverry, Guadalupe M\|Chinaleong, Jo-Anne\|Gunther, Thomas\|Silver, Andrew\|Clark, Susan K\|Tomlinson, Ian
PMID:	17258725

96.
Journal:	Oncogene. 2007 Jun 28;26(30):4435-41. Epub 2007 Jan 29.
Title:	Promoter methylation of the mutated in colorectal cancer gene is a frequent early event in colorectal cancer.
Author:	Kohonen-Corish, M R J\|Sigglekow, N D\|Susanto, J\|Chapuis, P H\|Bokey, E L\|Dent, O F\|Chan, C\|Lin, B P C\|Seng, T J\|Laird, P W\|Young, J\|Leggett, B A\|Jass, J R\|Sutherland, R L
PMID:	17260021

97.
Journal:	Hum Pathol. 2007 Apr;38(4):614-20. Epub 2007 Jan 31.
Title:	TGFBR2 mutation is correlated with CpG island methylator phenotype in microsatellite instability-high colorectal cancer.
Author:	Ogino, Shuji\|Kawasaki, Takako\|Ogawa, Akiyo\|Kirkner, Gregory J\|Loda, Massimo\|Fuchs, Charles S
PMID:	17270239

98.
Journal:	Mol Cancer Res. 2007 Feb;5(2):165-70. Epub 2007 Feb 9.
Title:	APC mutations and other genetic and epigenetic changes in colon cancer.
Author:	Samowitz, Wade S\|Slattery, Martha L\|Sweeney, Carol\|Herrick, Jennifer\|Wolff, Roger K\|Albertsen, Hans
PMID:	17293392

99.
Journal:	J Natl Cancer Inst. 2007 Feb 21;99(4):291-9.
Title:	Lynch syndrome (hereditary nonpolyposis colorectal cancer) diagnostics.
Author:	Lagerstedt Robinson, Kristina\|Liu, Tao\|Vandrovcova, Jana\|Halvarsson, Britta\|Clendenning, Mark\|Frebourg, Thierry\|Papadopoulos, Nickolas\|Kinzler, Kenneth W\|Vogelstein, Bert\|Peltomaki, Paivi\|Kolodner, Richard D\|Nilbert, Mef\|Lindblom, Annika
PMID:	17312306

100.
Journal:	Mol Cancer Res. 2007 Feb;5(2):195-201.
Title:	Phosphatidylinositol-3-OH kinase or RAS pathway mutations in human breast cancer cell lines.
Author:	Hollestelle, Antoinette\|Elstrodt, Fons\|Nagel, Jord H A\|Kallemeijn, Wouter W\|Schutte, Mieke
PMID:	17314276

101.
Journal:	Hum Pathol. 2007 Jun;38(6):842-9. Epub 2007 Mar 12.
Title:	Fatty acid synthase overexpression in colorectal cancer is associated with microsatellite instability, independent of CpG island methylator phenotype.
Author:	Ogino, Shuji\|Kawasaki, Takako\|Ogawa, Akiyo\|Kirkner, Gregory J\|Loda, Massimo\|Fuchs, Charles S
PMID:	17350669

102.
Journal:	Int J Biol Markers. 2007 Jan-Mar;22(1):12-8.
Title:	Highly conserved sequence of exon 15 BRAF gene and KRAS codon 12 mutation among Greek patients with colorectal cancer.
Author:	Symvoulakis, E K\|Zaravinos, A\|Panutsopulos, D\|Zoras, O\|Papalambros, E\|Sigala, F\|Spandidos, D A
PMID:	17393356

103.
Journal:	Eur J Surg Oncol. 2007 Jun;33(5):580-5. Epub 2007 Apr 3.
Title:	Chk1 frameshift mutation in sporadic and hereditary non-polyposis colorectal cancers with microsatellite instability.
Author:	Kim, C J\|Lee, J H\|Song, J W\|Cho, Y G\|Kim, S Y\|Nam, S W\|Yoo, N J\|Park, W S\|Lee, J Y
PMID:	17408908

104.
Journal:	J Pathol. 2007 Jun;212(2):124-33.
Title:	Role of BRAF-V600E in the serrated pathway of colorectal tumourigenesis.
Author:	Minoo, P\|Moyer, M P\|Jass, J R
PMID:	17427169

105.
Journal:	Mol Cancer Ther. 2007 Apr;6(4):1198-211.
Title:	Inhibition of the heat shock protein 90 molecular chaperone in vitro and in vivo by novel, synthetic, potent resorcinylic pyrazole/isoxazole amide analogues.
Author:	Sharp, Swee Y\|Prodromou, Chrisostomos\|Boxall, Kathy\|Powers, Marissa V\|Holmes, Joanna L\|Box, Gary\|Matthews, Thomas P\|Cheung, Kwai-Ming J\|Kalusa, Andrew\|James, Karen\|Hayes, Angela\|Hardcastle, Anthea\|Dymock, Brian\|Brough, Paul A\|Barril, Xavier\|Cansfield, Jul
PMID:	17431102

106.
Journal:	Cancer Res. 2007 Apr 15;67(8):3551-4.
Title:	Mutations in BRAF and KRAS differentially distinguish serrated versus non-serrated hyperplastic aberrant crypt foci in humans.
Author:	Rosenberg, Daniel W\|Yang, Shi\|Pleau, Devon C\|Greenspan, Emily J\|Stevens, Richard G\|Rajan, Thiruchandurai V\|Heinen, Christopher D\|Levine, Joel\|Zhou, Yijian\|O'Brien, Michael J
PMID:	17440063

107.
Journal:	Fam Cancer. 2007;6(3):301-10. Epub 2007 Apr 24.
Title:	Incorporation of somatic BRAF mutation testing into an algorithm for the investigation of hereditary non-polyposis colorectal cancer.
Author:	Loughrey, M B\|Waring, P M\|Tan, A\|Trivett, M\|Kovalenko, S\|Beshay, V\|Young, M-A\|McArthur, G\|Boussioutas, A\|Dobrovic, A
PMID:	17453358

108.
Journal:	Cancer J. 2007 Jan-Feb;13(1):49-55.
Title:	Targeting aberrant chromatin structure in colorectal carcinomas.
Author:	Konishi, Kazuo\|Issa, Jean-Pierre J
PMID:	17464246

109.
Journal:	BMC Cancer. 2007 May 2;7:72.
Title:	18q loss of heterozygosity in microsatellite stable colorectal cancer is correlated with CpG island methylator phenotype-negative (CIMP-0) and inversely with CIMP-low and CIMP-high.
Author:	Ogino, Shuji\|Kawasaki, Takako\|Kirkner, Gregory J\|Ohnishi, Mutsuko\|Fuchs, Charles S
PMID:	17474983

110.
Journal:	J Pathol. 2007 Aug;212(4):378-85.
Title:	Molecular classification and genetic pathways in hyperplastic polyposis syndrome.
Author:	Carvajal-Carmona, L G\|Howarth, K M\|Lockett, M\|Polanco-Echeverry, G M\|Volikos, E\|Gorman, M\|Barclay, E\|Martin, L\|Jones, A M\|Saunders, B\|Guenther, T\|Donaldson, A\|Paterson, J\|Frayling, I\|Novelli, M R\|Phillips, R\|Thomas, H J W\|Silver, A\|Atkin, W\|Tomlinson, I P
PMID:	17503413

111.
Journal:	Clin Cancer Res. 2007 Jun 1;13(11):3221-8.
Title:	Distinction of hereditary nonpolyposis colorectal cancer and sporadic microsatellite-unstable colorectal cancer through quantification of MLH1 methylation by real-time PCR.
Author:	Bettstetter, Marcus\|Dechant, Stephan\|Ruemmele, Petra\|Grabowski, Monika\|Keller, Gisela\|Holinski-Feder, Elke\|Hartmann, Arndt\|Hofstaedter, Ferdinand\|Dietmaier, Wolfgang
PMID:	17545526

112.
Journal:	Cancer Detect Prev. 2007;31(3):254-6. Epub 2007 Jun 12.
Title:	Frequency and application of the hot spot BRAF gene mutation (p.V600E) in the diagnostic strategy for Hereditary Nonpolyposis Colorectal Cancer.
Author:	Kadiyska, Tanya K\|Konstantinova, Darina V\|Atanasov, Venceslav R\|Kremensky, Ivo M\|Mitev, Vanio I
PMID:	17566669

113.
Journal:	J Mol Diagn. 2007 Jul;9(3):305-14.
Title:	Evaluation of markers for CpG island methylator phenotype (CIMP) in colorectal cancer by a large population-based sample.
Author:	Ogino, Shuji\|Kawasaki, Takako\|Kirkner, Gregory J\|Kraft, Peter\|Loda, Massimo\|Fuchs, Charles S
PMID:	17591929

114.
Journal:	Clin Cancer Res. 2007 Jul 1;13(13):3831-9.
Title:	Reduced likelihood of metastases in patients with microsatellite-unstable colorectal cancer.
Author:	Malesci, Alberto\|Laghi, Luigi\|Bianchi, Paolo\|Delconte, Gabriele\|Randolph, Ann\|Torri, Valter\|Carnaghi, Carlo\|Doci, Roberto\|Rosati, Riccardo\|Montorsi, Marco\|Roncalli, Massimo\|Gennari, Leandro\|Santoro, Armando
PMID:	17606714

115.
Journal:	Carcinogenesis. 2007 Sep;28(9):1985-90. Epub 2007 Jul 9.
Title:	MGMT germline polymorphism is associated with somatic MGMT promoter methylation and gene silencing in colorectal cancer.
Author:	Ogino, Shuji\|Hazra, Aditi\|Tranah, Gregory J\|Kirkner, Gregory J\|Kawasaki, Takako\|Nosho, Katsuhiko\|Ohnishi, Mutsuko\|Suemoto, Yuko\|Meyerhardt, Jeffrey A\|Hunter, David J\|Fuchs, Charles S
PMID:	17621591

116.
Journal:	J Mol Diagn. 2007 Sep;9(4):472-8. Epub 2007 Jul 25.
Title:	Heterogeneous staining for mismatch repair proteins during population-based prescreening for hereditary nonpolyposis colorectal cancer.
Author:	Watson, Natasha\|Grieu, Fabienne\|Morris, Melinda\|Harvey, Jennet\|Stewart, Colin\|Schofield, Lyn\|Goldblatt, Jack\|Iacopetta, Barry
PMID:	17652638

117.
Journal:	World J Gastroenterol. 2007 Aug 7;13(29):3932-8.
Title:	Involvement of Kruppel-like factor 6 (KLF6) mutation in the development of nonpolypoid colorectal carcinoma.
Author:	Mukai, Shinichi\|Hiyama, Toru\|Tanaka, Shinji\|Yoshihara, Masaharu\|Arihiro, Koji\|Chayama, Kazuaki
PMID:	17663506

118.
Journal:	Carcinogenesis. 2007 Sep;28(9):1851-8. Epub 2007 Aug 11.
Title:	Genetic pathways and mutation profiles of human cancers: site- and exposure-specific patterns.
Author:	Lea, I A\|Jackson, M A\|Li, X\|Bailey, S\|Peddada, S D\|Dunnick, J K
PMID:	17693665

119.
Journal:	Mol Cancer Ther. 2007 Aug;6(8):2220-9.
Title:	Context-dependent roles of mutant B-Raf signaling in melanoma and colorectal carcinoma cell growth.
Author:	Hao, Honglin\|Muniz-Medina, Vanessa M\|Mehta, Heena\|Thomas, Nancy E\|Khazak, Vladimir\|Der, Channing J\|Shields, Janiel M
PMID:	17699719

120.
Journal:	Neoplasia. 2007 Jul;9(7):569-77.
Title:	Correlation of beta-catenin localization with cyclooxygenase-2 expression and CpG island methylator phenotype (CIMP) in colorectal cancer.
Author:	Kawasaki, Takako\|Nosho, Katsuhiko\|Ohnishi, Mutsuko\|Suemoto, Yuko\|Kirkner, Gregory J\|Dehari, Reiko\|Meyerhardt, Jeffrey A\|Fuchs, Charles S\|Ogino, Shuji
PMID:	17710160

121.
Journal:	Invest Ophthalmol Vis Sci. 2007 Oct;48(10):4403-6.
Title:	Promoter methylation status of multiple genes in uveal melanoma.
Author:	Merhavi, Efrat\|Cohen, Yoram\|Avraham, Bat Chen R\|Frenkel, Shahar\|Chowers, Itay\|Pe'er, Jacob\|Goldenberg-Cohen, Nitza
PMID:	17898258

122.
Journal:	Clin Cancer Res. 2007 Oct 1;13(19):5729-35.
Title:	Molecular analysis of colorectal cancer tumors from patients with mismatch repair proficient hereditary nonpolyposis colorectal cancer suggests novel carcinogenic pathways.
Author:	Sanchez-de-Abajo, Ana\|de la Hoya, Miguel\|van Puijenbroek, Marjo\|Tosar, Alicia\|Lopez-Asenjo, J A\|Diaz-Rubio, Eduardo\|Morreau, Hans\|Caldes, Trinidad
PMID:	17908962

123.
Journal:	Oncol Rep. 2007 Nov;18(5):1093-7.
Title:	Involvement of the serrated neoplasia pathway in inflammatory bowel disease-related colorectal oncogenesis.
Author:	Bossard, Celine\|Denis, Marc G\|Bezieau, Stephane\|Bach-Ngohou, Kalyane\|Bourreille, Arnaud\|Laboisse, Christian L\|Mosnier, Jean-Francois
PMID:	17914558

124.
Journal:	Tumour Biol. 2007;28(5):290-300. Epub 2007 Oct 26.
Title:	Molecular testing for microsatellite instability and DNA mismatch repair defects in hereditary and sporadic colorectal cancers--ready for prime time?
Author:	Soreide, Kjetil
PMID:	17962726

125.
Journal:	Gastroenterol Clin North Am. 2007 Dec;36(4):947-68, viii.
Title:	Hyperplastic and serrated polyps of the colorectum.
Author:	O'Brien, Michael J
PMID:	17996799

126.
Journal:	Proc Natl Acad Sci U S A. 2007 Nov 20;104(47):18654-9. Epub 2007 Nov 14.
Title:	Integrated genetic and epigenetic analysis identifies three different subclasses of colon cancer.
Author:	Shen, Lanlan\|Toyota, Minoru\|Kondo, Yutaka\|Lin, E\|Zhang, Li\|Guo, Yi\|Hernandez, Natalie Supunpong\|Chen, Xinli\|Ahmed, Saira\|Konishi, Kazuo\|Hamilton, Stanley R\|Issa, Jean-Pierre J
PMID:	18003927

127.
Journal:	Cancer Epidemiol Biomarkers Prev. 2007 Nov;16(11):2344-50.
Title:	Frequency of defective DNA mismatch repair in colorectal cancer among the Alaska Native people.
Author:	Boardman, Lisa A\|Lanier, Anne P\|French, Amy J\|Schowalter, Karen V\|Burgart, Lawrence J\|Koller, Kathryn R\|McDonnell, Shannon K\|Schaid, Daniel J\|Thibodeau, Stephen N
PMID:	18006922

128.
Journal:	Cancer Epidemiol Biomarkers Prev. 2007 Dec;16(12):2686-96.
Title:	Highly methylated genes in colorectal neoplasia: implications for screening.
Author:	Zou, Hongzhi\|Harrington, Jonathan J\|Shire, Abdirashid M\|Rego, Rafaela L\|Wang, Liang\|Campbell, Megan E\|Oberg, Ann L\|Ahlquist, David A
PMID:	18086775

129.
Journal:	Cancer Res. 2007 Dec 15;67(24):11594-600.
Title:	Flat colorectal cancers are genetically determined and progress to invasion without going through a polypoid stage.
Author:	Uronis, Joshua M\|Herfarth, Hans H\|Rubinas, Tara C\|Bissahoyo, Anika C\|Hanlon, Kathleen\|Threadgill, David W
PMID:	18089788

130.
Journal:	Curr Med Chem. 2007;14(29):3122-38.
Title:	Drug-mediated targeted disruption of multiple protein activities through functional inhibition of the Hsp90 chaperone complex.
Author:	Stravopodis, Dimitrios J\|Margaritis, Lukas H\|Voutsinas, Gerassimos E
PMID:	18220746

131.
Journal:	Verh Dtsch Ges Pathol. 2007;91:119-25.
Title:	[Colorectal serrated adenoma: diagnostic criteria and clinical implications].
Author:	Ruschoff, J\|Aust, D\|Hartmann, A
PMID:	18314605

132.
Journal:	Rev Recent Clin Trials. 2007 May;2(2):121-34.
Title:	Therapeutic strategies for targeting BRAF in human cancer.
Author:	Pratilas, Christine A\|Solit, David B
PMID:	18473997

133.
Journal:	Ann Pathol. 2007 Dec;27(6):433-8.
Title:	[How and when to search for microsatellite instability in colorectal cancer in 2008?].
Author:	Paraf, Francois
PMID:	18554553

134.
Journal:	Colorectal Dis. 2008 Jun;10(5):490-7.
Title:	Strategy in clinical practice for classification of unselected colorectal tumours based on mismatch repair deficiency.
Author:	Jensen, L H\|Lindebjerg, J\|Byriel, L\|Kolvraa, S\|Cruger, D G
PMID:	17868408

135.
Journal:	Int J Colorectal Dis. 2008 Jan;23(1):7-13. Epub 2007 Oct 9.
Title:	Relationship of BRAF mutation, morphology, and apoptosis in early colorectal cancer.
Author:	Yoshida, Shiei\|Ikehara, Nobunao\|Aoyama, Nobuo\|Shirasaka, Daisuke\|Sakashita, Masanori\|Semba, Shuho\|Hasuo, Tadateru\|Miki, Ikuya\|Morita, Yoshinori\|Tamura, Takao\|Azuma, Takeshi\|Yokozaki, Hiroshi\|Kasuga, Masato
PMID:	17924122

136.
Journal:	J Biol Chem. 2008 Jan 4;283(1):529-40. Epub 2007 Nov 1.
Title:	Matrix metalloproteinase-activated anthrax lethal toxin demonstrates high potency in targeting tumor vasculature.
Author:	Liu, Shihui\|Wang, Hailun\|Currie, Brooke M\|Molinolo, Alfredo\|Leung, Howard J\|Moayeri, Mahtab\|Basile, John R\|Alfano, Randall W\|Gutkind, J Silvio\|Frankel, Arthur E\|Bugge, Thomas H\|Leppla, Stephen H
PMID:	17974567

137.
Journal:	Hum Mutat. 2008 Feb;29(2):284-8.
Title:	PIK3CA cancer mutations display gender and tissue specificity patterns.
Author:	Benvenuti, Silvia\|Frattini, Milo\|Arena, Sabrina\|Zanon, Carlo\|Cappelletti, Vera\|Coradini, Danila\|Daidone, Maria Grazia\|Pilotti, Silvana\|Pierotti, Marco A\|Bardelli, Alberto
PMID:	18022911

138.
Journal:	Carcinogenesis. 2008 Feb;29(2):434-9.
Title:	Integrated analysis of chromosomal, microsatellite and epigenetic instability in colorectal cancer identifies specific associations between promoter methylation of pivotal tumour suppressor and DNA repair genes and specific chromosomal alterations.
Author:	Derks, Sarah\|Postma, Cindy\|Carvalho, Beatriz\|van den Bosch, Sandra M\|Moerkerk, Peter T M\|Herman, James G\|Weijenberg, Matty P\|de Bruine, Adriaan P\|Meijer, Gerrit A\|van Engeland, Manon
PMID:	18048385

139.
Journal:	Gastroenterology. 2008 Jan;134(1):39-46. Epub 2007 Oct 26.
Title:	Validation and extension of the PREMM1,2 model in a population-based cohort of colorectal cancer patients.
Author:	Balaguer, Francesc\|Balmana, Judith\|Castellvi-Bel, Sergi\|Steyerberg, Ewout W\|Andreu, Montserrat\|Llor, Xavier\|Jover, Rodrigo\|Syngal, Sapna\|Castells, Antoni
PMID:	18061181

140.
Journal:	Mod Pathol. 2008 Feb;21(2):150-8. Epub 2007 Dec 14.
Title:	WRN promoter methylation possibly connects mucinous differentiation, microsatellite instability and CpG island methylator phenotype in colorectal cancer.
Author:	Kawasaki, Takako\|Ohnishi, Mutsuko\|Suemoto, Yuko\|Kirkner, Gregory J\|Liu, Zhiqian\|Yamamoto, Hiroyuki\|Loda, Massimo\|Fuchs, Charles S\|Ogino, Shuji
PMID:	18084250

141.
Journal:	Clin Gastroenterol Hepatol. 2008 Feb;6(2):206-14. Epub 2007 Dec 21.
Title:	A prospective, multicenter, population-based study of BRAF mutational analysis for Lynch syndrome screening.
Author:	Bessa, Xavier\|Balleste, Belen\|Andreu, Montserrat\|Castells, Antoni\|Bellosillo, Beatriz\|Balaguer, Francesc\|Castellvi-Bel, Sergi\|Paya, Artemio\|Jover, Rodrigo\|Alenda, Cristina\|Tito, Llucia\|Martinez-Villacampa, Mercedes\|Vilella, Angels\|Xicola, Rosa M\|Pons, Eli
PMID:	18096441

142.
Journal:	J Pathol. 2008 Feb;214(3):320-7.
Title:	BRAF provides proliferation and survival signals in MSI colorectal carcinoma cells displaying BRAF(V600E) but not KRAS mutations.
Author:	Preto, A\|Figueiredo, J\|Velho, S\|Ribeiro, A S\|Soares, P\|Oliveira, C\|Seruca, R
PMID:	18098337

143.
Journal:	Hum Mutat. 2008 Mar;29(3):441-50.
Title:	Rapid identification of somatic mutations in colorectal and breast cancer tissues using mismatch repair detection (MRD).
Author:	Bentivegna, Steven\|Zheng, Jianbiao\|Namsaraev, Eugeni\|Carlton, Victoria E H\|Pavlicek, Adam\|Moorhead, Martin\|Siddiqui, Farooq\|Wang, Zhiyong\|Lee, Liana\|Ireland, James S\|Suyenaga, Kent\|Willis, Thomas D\|Faham, Malek\|Seymour, Albert B
PMID:	18186519

144.
Journal:	Pathol Int. 2008 Feb;58(2):104-13.
Title:	Clinicopathological features of CpG island methylator phenotype-positive colorectal cancer and its adverse prognosis in relation to KRAS/BRAF mutation.
Author:	Lee, Sun\|Cho, Nam-Yun\|Choi, Minhee\|Yoo, Eun J\|Kim, Jung-Ho\|Kang, Gyeong H
PMID:	18199160

145.
Journal:	Am J Clin Pathol. 2008 Feb;129(2):238-44.
Title:	Clinicopathologic factors identify sporadic mismatch repair-defective colon cancers.
Author:	Halvarsson, Britta\|Anderson, Harald\|Domanska, Katarina\|Lindmark, Gudrun\|Nilbert, Mef
PMID:	18208804

146.
Journal:	Int J Cancer. 2008 May 15;122(10):2255-9.
Title:	Mutations in the RAS-MAPK, PI(3)K (phosphatidylinositol-3-OH kinase) signaling network correlate with poor survival in a population-based series of colon cancers.
Author:	Barault, Ludovic\|Veyrie, Nicolas\|Jooste, Valerie\|Lecorre, Delphine\|Chapusot, Caroline\|Ferraz, Jean-Marc\|Lievre, Astrid\|Cortet, Marion\|Bouvier, Anne-Marie\|Rat, Patrick\|Roignot, Patrick\|Faivre, Jean\|Laurent-Puig, Pierre\|Piard, Francoise
PMID:	18224685

147.
Journal:	Am J Surg Pathol. 2008 Mar;32(3):407-12.
Title:	Serrated polyps with "intermediate features" of sessile serrated polyp and microvesicular hyperplastic polyp: a practical approach to the classification of nondysplastic serrated polyps.
Author:	Chung, Sun M\|Chen, Yao-Tseng\|Panczykowski, Andrea\|Schamberg, Neal\|Klimstra, David S\|Yantiss, Rhonda K
PMID:	18300810

148.
Journal:	Genes Chromosomes Cancer. 2008 Jun;47(6):449-60.
Title:	Bone morphogenic protein 3 inactivation is an early and frequent event in colorectal cancer development.
Author:	Loh, Kim\|Chia, June A\|Greco, Sonia\|Cozzi, Sarah-Jane\|Buttenshaw, Ron L\|Bond, Catherine E\|Simms, Lisa A\|Pike, Tanya\|Young, Joanne P\|Jass, Jeremy R\|Spring, Kevin J\|Leggett, Barbara A\|Whitehall, Vicki L J
PMID:	18311777

149.
Journal:	Carcinogenesis. 2008 Sep;29(9):1765-73.
Title:	Associations of dietary methyl donor intake with MLH1 promoter hypermethylation and related molecular phenotypes in sporadic colorectal cancer.
Author:	de Vogel, Stefan\|Bongaerts, Brenda W C\|Wouters, Kim A D\|Kester, Arnold D M\|Schouten, Leo J\|de Goeij, Anton F P M\|de Bruine, Adriaan P\|Goldbohm, R Alexandra\|van den Brandt, Piet A\|van Engeland, Manon\|Weijenberg, Matty P
PMID:	18339680

150.
Journal:	Cancer Res. 2008 Mar 15;68(6):1953-61.
Title:	PIK3CA mutation/PTEN expression status predicts response of colon cancer cells to the epidermal growth factor receptor inhibitor cetuximab.
Author:	Jhawer, Minaxi\|Goel, Sanjay\|Wilson, Andrew J\|Montagna, Cristina\|Ling, Yi-He\|Byun, Do-Sun\|Nasser, Shannon\|Arango, Diego\|Shin, Joongho\|Klampfer, Lidija\|Augenlicht, Leonard H\|Perez-Soler, Roman\|Mariadason, John M
PMID:	18339877

151.
Journal:	Int J Cancer. 2008 Jun 15;122(12):2767-73.
Title:	LINE-1 hypomethylation is inversely associated with microsatellite instability and CpG island methylator phenotype in colorectal cancer.
Author:	Ogino, Shuji\|Kawasaki, Takako\|Nosho, Katsuhiko\|Ohnishi, Mutsuko\|Suemoto, Yuko\|Kirkner, Gregory J\|Fuchs, Charles S
PMID:	18366060

152.
Journal:	Mol Cancer Res. 2008 Apr;6(4):585-91.
Title:	The CpG island methylator phenotype correlates with long-range epigenetic silencing in colorectal cancer.
Author:	Karpinski, Pawel\|Ramsey, David\|Grzebieniak, Zygmunt\|Sasiadek, Maria M\|Blin, Nikolaus
PMID:	18403637

153.
Journal:	Mutat Res. 2008 Jul-Aug;659(1-2):109-17.
Title:	Sixty years of follow-up of Hiroshima and Nagasaki survivors: current progress in molecular epidemiology studies.
Author:	Nakachi, Kei\|Hayashi, Tomonori\|Hamatani, Kiyohiro\|Eguchi, Hidetaka\|Kusunoki, Yoichiro
PMID:	18406659

154.
Journal:	Pathology. 2008 Apr;40(3):295-8.
Title:	Detection of BRAF V600E mutation by pyrosequencing.
Author:	Tan, Yi Hui\|Liu, Yanqun\|Eu, Kong Weng\|Ang, Pei Woon\|Li, Wei Qi\|Salto-Tellez, Manuel\|Iacopetta, Barry\|Soong, Richie
PMID:	18428050

155.
Journal:	Gastroenterology. 2008 Jun;134(7):1950-60, 1960.e1.
Title:	Mutations in both KRAS and BRAF may contribute to the methylator phenotype in colon cancer.
Author:	Nagasaka, Takeshi\|Koi, Minoru\|Kloor, Matthias\|Gebert, Johannes\|Vilkin, Alex\|Nishida, Naoshi\|Shin, Sung Kwan\|Sasamoto, Hiromi\|Tanaka, Noriaki\|Matsubara, Nagahide\|Boland, C Richard\|Goel, Ajay
PMID:	18435933

156.
Journal:	Clin Cancer Res. 2008 May 1;14(9):2560-9.
Title:	Epigenetic-genetic interactions in the APC/WNT, RAS/RAF, and P53 pathways in colorectal carcinoma.
Author:	Suehiro, Yutaka\|Wong, Chi Wai\|Chirieac, Lucian R\|Kondo, Yutaka\|Shen, Lanlan\|Webb, C Renee\|Chan, Yee Wai\|Chan, Annie S Y\|Chan, Tsun Leung\|Wu, Tsung-Teh\|Rashid, Asif\|Hamanaka, Yuichiro\|Hinoda, Yuji\|Shannon, Rhonda L\|Wang, Xuemei\|Morris, Jeffrey\|Issa, Jean-P
PMID:	18451217

157.
Journal:	Mol Cancer Res. 2008 May;6(5):751-9.
Title:	BRAF silencing by short hairpin RNA or chemical blockade by PLX4032 leads to different responses in melanoma and thyroid carcinoma cells.
Author:	Sala, Elisa\|Mologni, Luca\|Truffa, Silvia\|Gaetano, Carlo\|Bollag, Gideon E\|Gambacorti-Passerini, Carlo
PMID:	18458053

158.
Journal:	Cancer. 2008 Jul 15;113(2):247-55.
Title:	Hypermethylation of the DNA mismatch repair gene hMLH1 and its association with lymph node metastasis and T1799A BRAF mutation in patients with papillary thyroid cancer.
Author:	Guan, Haixia\|Ji, Meiju\|Hou, Peng\|Liu, Zhi\|Wang, Cuifang\|Shan, Zhongyan\|Teng, Weiping\|Xing, Mingzhao
PMID:	18470905

159.
Journal:	Eur J Cancer. 2008 Jun;44(9):1290-301.
Title:	Proximal and distal colorectal cancers show distinct gene-specific methylation profiles and clinical and molecular characteristics.
Author:	Deng, Guoren\|Kakar, Sanjay\|Tanaka, Hirofumi\|Matsuzaki, Koji\|Miura, Soichiro\|Sleisenger, Marvin H\|Kim, Young S
PMID:	18486467

160.
Journal:	Arch Pathol Lab Med. 2008 Jun;132(6):958-64.
Title:	Clinicopathologic characteristics, CpG island methylator phenotype, and BRAF mutations in microsatellite-stable colorectal cancers without chromosomal instability.
Author:	Kakar, Sanjay\|Deng, Guoren\|Sahai, Vaibhav\|Matsuzaki, Koji\|Tanaka, Hirofumi\|Miura, Soichuro\|Kim, Young S
PMID:	18517279

161.
Journal:	Clin Cancer Res. 2008 Jun 1;14(11):3408-15.
Title:	Prognostic significance of defective mismatch repair and BRAF V600E in patients with colon cancer.
Author:	French, Amy J\|Sargent, Daniel J\|Burgart, Lawrence J\|Foster, Nathan R\|Kabat, Brian F\|Goldberg, Richard\|Shepherd, Lois\|Windschitl, Harold E\|Thibodeau, Stephen N
PMID:	18519771

162.
Journal:	Mol Cancer Ther. 2008 Jun;7(6):1337-46.
Title:	In vitro differential sensitivity of melanomas to phenothiazines is based on the presence of codon 600 BRAF mutation.
Author:	Ikediobi, Ogechi N\|Reimers, Mark\|Durinck, Steffen\|Blower, Paul E\|Futreal, Andrew P\|Stratton, Michael R\|Weinstein, John N
PMID:	18524847

163.
Journal:	J Mol Diagn. 2008 Jul;10(4):301-7.
Title:	Immunohistochemistry versus microsatellite instability testing for screening colorectal cancer patients at risk for hereditary nonpolyposis colorectal cancer syndrome. Part II. The utility of microsatellite instability testing.
Author:	Zhang, Liying
PMID:	18556776

164.
Journal:	World J Gastroenterol. 2008 Jun 14;14(22):3461-3.
Title:	Heterogeneity of colorectal adenomas, the serrated adenoma, and implications for screening and surveillance.
Author:	Freeman, Hugh-James
PMID:	18567071

165.
Journal:	Oncol Rep. 2008 Jul;20(1):3-11.
Title:	Analysis of the K-ras/B-raf/Erk signal cascade, p53 and CMAP as markers for tumor progression in colorectal cancer patients.
Author:	Georgieva, Milka\|Krasteva, Maria\|Angelova, Elka\|Ralchev, Krassimir\|Dimitrov, Valentin\|Bozhimirov, Stanislav\|Georgieva, Elena\|Berger, Martin R
PMID:	18575712

166.
Journal:	Br J Cancer. 2008 Jul 8;99(1):83-9.
Title:	Primary resistance to cetuximab therapy in EGFR FISH-positive colorectal cancer patients.
Author:	Cappuzzo, F\|Varella-Garcia, M\|Finocchiaro, G\|Skokan, M\|Gajapathy, S\|Carnaghi, C\|Rimassa, L\|Rossi, E\|Ligorio, C\|Di Tommaso, L\|Holmes, A J\|Toschi, L\|Tallini, G\|Destro, A\|Roncalli, M\|Santoro, A\|Janne, P A
PMID:	18577988

167.
Journal:	Oncogene. 2008 Oct 9;27(46):6044-55.
Title:	Mutated in colorectal cancer, a putative tumor suppressor for serrated colorectal cancer, selectively represses beta-catenin-dependent transcription.
Author:	Fukuyama, R\|Niculaita, R\|Ng, K P\|Obusez, E\|Sanchez, J\|Kalady, M\|Aung, P P\|Casey, G\|Sizemore, N
PMID:	18591935

168.
Journal:	Neoplasia. 2008 Jul;10(7):680-6, 2 p following 686.
Title:	RAS signaling in colorectal carcinomas through alteration of RAS, RAF, NF1, and/or RASSF1A.
Author:	Ahlquist, Terje\|Bottillo, Irene\|Danielsen, Stine A\|Meling, Gunn I\|Rognum, Torleiv O\|Lind, Guro E\|Dallapiccola, Bruno\|Lothe, Ragnhild A
PMID:	18592002

169.
Journal:	Gastroenterology. 2008 Sep;135(3):899-906.
Title:	B-Raf(V600E) cooperates with alternative spliced Rac1b to sustain colorectal cancer cell survival.
Author:	Matos, Paulo\|Oliveira, Carla\|Velho, Sergia\|Goncalves, Vania\|da Costa, Luis Teixiera\|Moyer, Mary Pat\|Seruca, Raquel\|Jordan, Peter
PMID:	18602919

170.
Journal:	Genes Chromosomes Cancer. 2008 Oct;47(10):835-44.
Title:	The MLH1 -93 G>A promoter polymorphism and genetic and epigenetic alterations in colon cancer.
Author:	Samowitz, Wade S\|Curtin, Karen\|Wolff, Roger K\|Albertsen, Hans\|Sweeney, Carol\|Caan, Bette J\|Ulrich, Cornelia M\|Potter, John D\|Slattery, Martha L
PMID:	18615680

171.
Journal:	Hum Pathol. 2008 Sep;39(9):1301-8.
Title:	Genetic alterations in colorectal cancers with demethylation of insulin-like growth factor II.
Author:	Ohta, Miki\|Sugimoto, Takafumi\|Seto, Motoko\|Mohri, Dai\|Asaoka, Yoshinari\|Tada, Motohisa\|Tanaka, Yasuo\|Yamaji, Yutaka\|Kanai, Fumihiko\|Kawabe, Takao\|Omata, Masao
PMID:	18619647

172.
Journal:	Am J Clin Pathol. 2008 Aug;130(2):247-53.
Title:	High-resolution melting analysis for rapid detection of KRAS, BRAF, and PIK3CA gene mutations in colorectal cancer.
Author:	Simi, Lisa\|Pratesi, Nicola\|Vignoli, Marina\|Sestini, Roberta\|Cianchi, Fabio\|Valanzano, Rosa\|Nobili, Stefania\|Mini, Enrico\|Pazzagli, Mario\|Orlando, Claudio
PMID:	18628094

173.
Journal:	Cancer Epidemiol Biomarkers Prev. 2008 Jul;17(7):1774-80.
Title:	Ethnicity and risk for colorectal cancers showing somatic BRAF V600E mutation or CpG island methylator phenotype.
Author:	English, Dallas R\|Young, Joanne P\|Simpson, Julie A\|Jenkins, Mark A\|Southey, Melissa C\|Walsh, Michael D\|Buchanan, Daniel D\|Barker, Melissa A\|Haydon, Andrew M\|Royce, Simon G\|Roberts, Aedan\|Parry, Susan\|Hopper, John L\|Jass, Jeremy J\|Giles, Graham G
PMID:	18628431

174.
Journal:	Magy Onkol. 2008 Jun;52(2):185-91.
Title:	[The RAS paradox of the EGFR-targeted therapy in colorectal cancer].
Author:	Timar, Jozsef\|Lang, Istvan
PMID:	18640895

175.
Journal:	Cancer Res. 2008 Aug 1;68(15):6324-30.
Title:	Oxidative stress plays a critical role in inactivating mutant BRAF by geldanamycin derivatives.
Author:	Fukuyo, Yayoi\|Inoue, Masahiro\|Nakajima, Takuma\|Higashikubo, Ryuji\|Horikoshi, Nobuko T\|Hunt, Clayton\|Usheva, Anny\|Freeman, Michael L\|Horikoshi, Nobuo
PMID:	18676857

176.
Journal:	Mol Cancer. 2008 Aug 21;7:68.
Title:	Impact of BRAF, MLH1 on the incidence of microsatellite instability high colorectal cancer in populations based study.
Author:	Brim, Hassan\|Mokarram, Pooneh\|Naghibalhossaini, Fakhraddin\|Saberi-Firoozi, Mehdi\|Al-Mandhari, Mansour\|Al-Mawaly, Kamla\|Al-Mjeni, Rayhaneh\|Al-Sayegh, Abeer\|Raeburn, Sandy\|Lee, Edward\|Giardiello, Francis\|Smoot, Duane T\|Vilkin, Alexander\|Boland, C Richard\|Go
PMID:	18718023

177.
Journal:	Am J Gastroenterol. 2008 Nov;103(11):2825-35; quiz 2836.
Title:	Identification in daily practice of patients with Lynch syndrome (hereditary nonpolyposis colorectal cancer): revised Bethesda guidelines-based approach versus molecular screening.
Author:	Julie, Catherine\|Tresallet, Christophe\|Brouquet, Antoine\|Vallot, Celine\|Zimmermann, Ute\|Mitry, Emmanuel\|Radvanyi, Francois\|Rouleau, Etienne\|Lidereau, Rosette\|Coulet, Florence\|Olschwang, Sylviane\|Frebourg, Thierry\|Rougier, Philippe\|Nordlinger, Bernard\|Laur
PMID:	18759827

178.
Journal:	BMC Cancer. 2008 Sep 9;8:255.
Title:	BRAF, KRAS and PIK3CA mutations in colorectal serrated polyps and cancer: primary or secondary genetic events in colorectal carcinogenesis?
Author:	Velho, Sergia\|Moutinho, Catia\|Cirnes, Luis\|Albuquerque, Cristina\|Hamelin, Richard\|Schmitt, Fernando\|Carneiro, Fatima\|Oliveira, Carla\|Seruca, Raquel
PMID:	18782444

179.
Journal:	Mol Cancer Ther. 2008 Sep;7(9):3112-21.
Title:	Noninvasive imaging of cell proliferation following mitogenic extracellular kinase inhibition by PD0325901.
Author:	Leyton, Julius\|Smith, Graham\|Lees, Mark\|Perumal, Meg\|Nguyen, Quang-de\|Aigbirhio, Franklin I\|Golovko, Oksana\|He, Quimin\|Workman, Paul\|Aboagye, Eric O
PMID:	18790789

180.
Journal:	Int J Cancer. 2008 Dec 1;123(11):2587-93.
Title:	Distinct CpG island methylation profiles and BRAF mutation status in serrated and adenomatous colorectal polyps.
Author:	Kim, Yong Ho\|Kakar, Sanjay\|Cun, Lisa\|Deng, Guoren\|Kim, Young S
PMID:	18798261

181.
Journal:	Curr Gastroenterol Rep. 2008 Oct;10(5):490-8.
Title:	Significance of serrated polyps of the colon.
Author:	Groff, Rachel J\|Nash, Russell\|Ahnen, Dennis J
PMID:	18799125

182.
Journal:	Oncogene. 2008 Dec 4;27(57):7150-61.
Title:	Colorectal cancer cells with the BRAF(V600E) mutation are addicted to the ERK1/2 pathway for growth factor-independent survival and repression of BIM.
Author:	Wickenden, J A\|Jin, H\|Johnson, M\|Gillings, A S\|Newson, C\|Austin, M\|Chell, S D\|Balmanno, K\|Pritchard, C A\|Cook, S J
PMID:	18806830

183.
Journal:	Clin Cancer Res. 2008 Oct 1;14(19):6005-13.
Title:	CpG island methylator phenotype associates with low-degree chromosomal abnormalities in colorectal cancer.
Author:	Cheng, Yu-Wei\|Pincas, Hanna\|Bacolod, Manny D\|Schemmann, Gunter\|Giardina, Sarah F\|Huang, Jianmin\|Barral, Sandra\|Idrees, Kamran\|Khan, Sajid A\|Zeng, Zhaoshi\|Rosenberg, Shoshana\|Notterman, Daniel A\|Ott, Jurg\|Paty, Philip\|Barany, Francis
PMID:	18829479

184.
Journal:	Arch Pathol Lab Med. 2008 Oct;132(10):1657-65.
Title:	CpG island methylator phenotype in colorectal cancers: comparison of the new and classic CpG island methylator phenotype marker panels.
Author:	Lee, Sun\|Cho, Nam-Yun\|Yoo, Eun Joo\|Kim, Jung Ho\|Kang, Gyeong Hoon
PMID:	18834226

185.
Journal:	Cancer Res. 2008 Oct 15;68(20):8541-6.
Title:	Hypermethylator phenotype in sporadic colon cancer: study on a population-based series of 582 cases.
Author:	Barault, Ludovic\|Charon-Barra, Celine\|Jooste, Valerie\|de la Vega, Mathilde Funes\|Martin, Laurent\|Roignot, Patrick\|Rat, Patrick\|Bouvier, Anne-Marie\|Laurent-Puig, Pierre\|Faivre, Jean\|Chapusot, Caroline\|Piard, Francoise
PMID:	18922929

186.
Journal:	Eur J Cancer. 2008 Nov;44(17):2689-95.
Title:	Epigenetic events in normal colonic mucosa surrounding colorectal cancer lesions.
Author:	Ramirez, N\|Bandres, E\|Navarro, A\|Pons, A\|Jansa, S\|Moreno, I\|Martinez-Rodenas, F\|Zarate, R\|Bitarte, N\|Monzo, M\|Garcia-Foncillas, J
PMID:	18938072

187.
Journal:	J Clin Oncol. 2008 Dec 10;26(35):5713-20.
Title:	Cohort study of fatty acid synthase expression and patient survival in colon cancer.
Author:	Ogino, Shuji\|Nosho, Katsuhiko\|Meyerhardt, Jeffrey A\|Kirkner, Gregory J\|Chan, Andrew T\|Kawasaki, Takako\|Giovannucci, Edward L\|Loda, Massimo\|Fuchs, Charles S
PMID:	18955444

188.
Journal:	Histopathology. 2008 Nov;53(5):588-98.
Title:	Cyclin D1 is frequently overexpressed in microsatellite unstable colorectal cancer, independent of CpG island methylator phenotype.
Author:	Nosho, K\|Kawasaki, T\|Chan, A T\|Ohnishi, M\|Suemoto, Y\|Kirkner, G J\|Fuchs, C S\|Ogino, S
PMID:	18983468

189.
Journal:	Cancer Genet Cytogenet. 2008 Nov;187(1):12-8.
Title:	Prevalence of mutations in APC, CTNNB1, and BRAF in Tunisian patients with sporadic colorectal cancer.
Author:	Bougatef, Karim\|Ouerhani, Slah\|Moussa, Amel\|Kourda, Nadia\|Coulet, Florence\|Colas, Chrystelle\|Lahely, Yannick Blondeau\|Najjar, Tawfik\|Ben Jilani, Sarra\|Benammar-Elgaaied, Amel\|Soubrier, Florent\|Marrakchi, Raja
PMID:	18992635

190.
Journal:	J Clin Oncol. 2008 Dec 10;26(35):5705-12.
Title:	Wild-type BRAF is required for response to panitumumab or cetuximab in metastatic colorectal cancer.
Author:	Di Nicolantonio, Federica\|Martini, Miriam\|Molinari, Francesca\|Sartore-Bianchi, Andrea\|Arena, Sabrina\|Saletti, Piercarlo\|De Dosso, Sara\|Mazzucchelli, Luca\|Frattini, Milo\|Siena, Salvatore\|Bardelli, Alberto
PMID:	19001320

191.
Journal:	PLoS One. 2008;3(11):e3698.
Title:	Comprehensive biostatistical analysis of CpG island methylator phenotype in colorectal cancer using a large population-based sample.
Author:	Nosho, Katsuhiko\|Irahara, Natsumi\|Shima, Kaori\|Kure, Shoko\|Kirkner, Gregory J\|Schernhammer, Eva S\|Hazra, Aditi\|Hunter, David J\|Quackenbush, John\|Spiegelman, Donna\|Giovannucci, Edward L\|Fuchs, Charles S\|Ogino, Shuji
PMID:	19002263

192.
Journal:	Br J Cancer. 2008 Dec 16;99(12):2001-5.
Title:	Statistical strategies to improve the efficiency of molecular studies of colorectal cancer prognosis.
Author:	Qu, P\|Chu, H\|Ibrahim, J G\|Peacock, J\|Shen, X J\|Tepper, J\|Sandler, R S\|Keku, T O
PMID:	19018265

193.
Journal:	J Natl Cancer Inst. 2008 Dec 3;100(23):1734-8.
Title:	A cohort study of tumoral LINE-1 hypomethylation and prognosis in colon cancer.
Author:	Ogino, Shuji\|Nosho, Katsuhiko\|Kirkner, Gregory J\|Kawasaki, Takako\|Chan, Andrew T\|Schernhammer, Eva S\|Giovannucci, Edward L\|Fuchs, Charles S
PMID:	19033568

194.
Journal:	Mol Cancer. 2008 Dec 16;7:92.
Title:	Gene expression deregulation by KRAS G12D and G12V in a BRAF V600E context.
Author:	Monticone, Massimiliano\|Biollo, Emanuela\|Maffei, Massimo\|Donadini, Alessandra\|Romeo, Francesco\|Storlazzi, Clelia Tiziana\|Giaretti, Walter\|Castagnola, Patrizio
PMID:	19087308

195.
Journal:	Clin Cancer Res. 2008 Dec 15;14(24):8221-7.
Title:	Cyclooxygenase-2 expression is an independent predictor of poor prognosis in colon cancer.
Author:	Ogino, Shuji\|Kirkner, Gregory J\|Nosho, Katsuhiko\|Irahara, Natsumi\|Kure, Shoko\|Shima, Kaori\|Hazra, Aditi\|Chan, Andrew T\|Dehari, Reiko\|Giovannucci, Edward L\|Fuchs, Charles S
PMID:	19088039

196.
Journal:	Mol Cancer. 2008 Dec 31;7:94.
Title:	Gene methylation profiles of normal mucosa, and benign and malignant colorectal tumors identify early onset markers.
Author:	Ahlquist, Terje\|Lind, Guro E\|Costa, Vera L\|Meling, Gunn I\|Vatn, Morten\|Hoff, Geir S\|Rognum, Torleiv O\|Skotheim, Rolf I\|Thiis-Evensen, Espen\|Lothe, Ragnhild A
PMID:	19117505

197.
Journal:	Clin Colon Rectal Surg. 2008 Nov;21(4):273-9.
Title:	Management of serrated adenomas and hyperplastic polyps.
Author:	Bauer, Valerie P\|Papaconstantinou, Harry T
PMID:	20011438

198.
Journal:	Ann Oncol. 2009 Jan;20(1):84-90.
Title:	PI3KCA/PTEN deregulation contributes to impaired responses to cetuximab in metastatic colorectal cancer patients.
Author:	Perrone, F\|Lampis, A\|Orsenigo, M\|Di Bartolomeo, M\|Gevorgyan, A\|Losa, M\|Frattini, M\|Riva, C\|Andreola, S\|Bajetta, E\|Bertario, L\|Leo, E\|Pierotti, M A\|Pilotti, S
PMID:	18669866

199.
Journal:	Genes Chromosomes Cancer. 2009 Jan;48(1):1-9.
Title:	Oncogenetic tree model of somatic mutations and DNA methylation in colon tumors.
Author:	Sweeney, Carol\|Boucher, Kenneth M\|Samowitz, Wade S\|Wolff, Roger K\|Albertsen, Hans\|Curtin, Karen\|Caan, Bette J\|Slattery, Martha L
PMID:	18767147

200.
Journal:	Cancer Lett. 2009 Jan 18;273(2):221-4.
Title:	BRAF mutation is associated with the CpG island methylator phenotype in colorectal cancer from young patients.
Author:	Ang, Pei Woon\|Li, Wei Qi\|Soong, Richie\|Iacopetta, Barry
PMID:	18778891

201.
Journal:	Gut. 2009 Jan;58(1):90-6.
Title:	CpG island methylator phenotype, microsatellite instability, BRAF mutation and clinical outcome in colon cancer.
Author:	Ogino, Shuji\|Nosho, Katsuhiko\|Kirkner, Gregory J\|Kawasaki, Takako\|Meyerhardt, Jeffrey A\|Loda, Massimo\|Giovannucci, Edward L\|Fuchs, Charles S
PMID:	18832519

202.
Journal:	Cell Death Differ. 2009 Mar;16(3):368-77.
Title:	Tumour cell survival signalling by the ERK1/2 pathway.
Author:	Balmanno, K\|Cook, S J
PMID:	18846109

203.
Journal:	Cancer Lett. 2009 Feb 18;274(2):266-70.
Title:	Endometrial cancer and somatic G>T KRAS transversion in patients with constitutional MUTYH biallelic mutations.
Author:	Tricarico, Rossella\|Bet, Paola\|Ciambotti, Benedetta\|Di Gregorio, Carmela\|Gatteschi, Beatrice\|Gismondi, Viviana\|Toschi, Benedetta\|Tonelli, Francesco\|Varesco, Liliana\|Genuardi, Maurizio
PMID:	18980800

204.
Journal:	Gastroenterology. 2009 Feb;136(2):459-70.
Title:	High detection rates of colorectal neoplasia by stool DNA testing with a novel digital melt curve assay.
Author:	Zou, Hongzhi\|Taylor, William R\|Harrington, Jonathan J\|Hussain, Fareeda Taher Nazer\|Cao, Xiaoming\|Loprinzi, Charles L\|Levine, Theodore R\|Rex, Douglas K\|Ahnen, Dennis\|Knigge, Kandice L\|Lance, Peter\|Jiang, Xuan\|Smith, David I\|Ahlquist, David A
PMID:	19026650

205.
Journal:	Am J Surg Pathol. 2009 Apr;33(4):572-82.
Title:	Clinical, pathologic, and molecular features of early-onset colorectal carcinoma.
Author:	Yantiss, Rhonda K\|Goodarzi, Mahmoud\|Zhou, Xi K\|Rennert, Hanna\|Pirog, Edyta C\|Banner, Barbara F\|Chen, Yao-Tseng
PMID:	19047896

206.
Journal:	Int J Cancer. 2009 Mar 1;124(5):1097-102.
Title:	Population-based detection of Lynch syndrome in young colorectal cancer patients using microsatellite instability as the initial test.
Author:	Schofield, Lyn\|Watson, Natasha\|Grieu, Fabienne\|Li, Wei Qi\|Zeps, Nik\|Harvey, Jennet\|Stewart, Colin\|Abdo, Michael\|Goldblatt, Jack\|Iacopetta, Barry
PMID:	19072991

207.
Journal:	Neoplasia. 2009 Jan;11(1):87-95.
Title:	JC virus T-antigen in colorectal cancer is associated with p53 expression and chromosomal instability, independent of CpG island methylator phenotype.
Author:	Nosho, Katsuhiko\|Shima, Kaori\|Kure, Shoko\|Irahara, Natsumi\|Baba, Yoshifumi\|Chen, Li\|Kirkner, Gregory J\|Fuchs, Charles S\|Ogino, Shuji
PMID:	19107235

208.
Journal:	Cancer Treat Rev. 2009 May;35(3):262-71.
Title:	Clinical relevance of EGFR- and KRAS-status in colorectal cancer patients treated with monoclonal antibodies directed against the EGFR.
Author:	Heinemann, Volker\|Stintzing, Sebastian\|Kirchner, Thomas\|Boeck, Stefan\|Jung, Andreas
PMID:	19117687

209.
Journal:	Cancer. 2009 Feb 15;115(4):760-9.
Title:	Microsatellite instability, MLH1 promoter methylation, and BRAF mutation analysis in sporadic colorectal cancers of different ethnic groups in Israel.
Author:	Vilkin, Alex\|Niv, Yaron\|Nagasaka, Takeshi\|Morgenstern, Sarah\|Levi, Zohar\|Fireman, Zvi\|Fuerst, Florentine\|Goel, Ajay\|Boland, C Richard
PMID:	19127559

210.
Journal:	Carcinogenesis. 2009 Mar;30(3):494-9.
Title:	Microsatellite instability-low colorectal cancer acquires a KRAS mutation during the progression from Dukes' A to Dukes' B.
Author:	Asaka, Shin-ichi\|Arai, Yoshiko\|Nishimura, Yoji\|Yamaguchi, Kensei\|Ishikubo, Tsutomu\|Yatsuoka, Toshimasa\|Tanaka, Yoichi\|Akagi, Kiwamu
PMID:	19147861

211.
Journal:	Ann Oncol. 2009 Jul;20(7):1216-22.
Title:	MGMT and MLH1 promoter methylation versus APC, KRAS and BRAF gene mutations in colorectal cancer: indications for distinct pathways and sequence of events.
Author:	de Vogel, S\|Weijenberg, M P\|Herman, J G\|Wouters, K A D\|de Goeij, A F P M\|van den Brandt, P A\|de Bruine, A P\|van Engeland, M
PMID:	19164452

212.
Journal:	Gastroenterology. 2009 Apr;136(4):1242-50.
Title:	Colorectal cancer expression of peroxisome proliferator-activated receptor gamma (PPARG, PPARgamma) is associated with good prognosis.
Author:	Ogino, Shuji\|Shima, Kaori\|Baba, Yoshifumi\|Nosho, Katsuhiko\|Irahara, Natsumi\|Kure, Shoko\|Chen, Li\|Toyoda, Saori\|Kirkner, Gregory J\|Wang, Y Lynn\|Giovannucci, Edward L\|Fuchs, Charles S
PMID:	19186181

213.
Journal:	Clin Cancer Res. 2009 Feb 15;15(4):1155-61.
Title:	Distinct BRAF (V600E) and KRAS mutations in high microsatellite instability sporadic colorectal cancer in African Americans.
Author:	Kumar, Krishan\|Brim, Hassan\|Giardiello, Francis\|Smoot, Duane T\|Nouraie, Mehdi\|Lee, Edward L\|Ashktorab, Hassan
PMID:	19190129

214.
Journal:	Gastroenterology. 2009 May;136(5):1680-8.e7.
Title:	TGF-beta receptor inactivation and mutant Kras induce intestinal neoplasms in mice via a beta-catenin-independent pathway.
Author:	Trobridge, Patty\|Knoblaugh, Sue\|Washington, M Kay\|Munoz, Nina M\|Tsuchiya, Karen D\|Rojas, Andres\|Song, Xiaoling\|Ulrich, Cornelia M\|Sasazuki, Takehiko\|Shirasawa, Senji\|Grady, William M
PMID:	19208363

215.
Journal:	J Mol Diagn. 2009 Mar;11(2):140-7.
Title:	Evaluation of high-resolution melting analysis as a diagnostic tool to detect the BRAF V600E mutation in colorectal tumors.
Author:	Pichler, Martin\|Balic, Marija\|Stadelmeyer, Elke\|Ausch, Christoph\|Wild, Martina\|Guelly, Christian\|Bauernhofer, Thomas\|Samonigg, Hellmut\|Hoefler, Gerald\|Dandachi, Nadia
PMID:	19213871

216.
Journal:	Cancer Res. 2009 Mar 1;69(5):1851-7.
Title:	PIK3CA mutations in colorectal cancer are associated with clinical resistance to EGFR-targeted monoclonal antibodies.
Author:	Sartore-Bianchi, Andrea\|Martini, Miriam\|Molinari, Francesca\|Veronese, Silvio\|Nichelatti, Michele\|Artale, Salvatore\|Di Nicolantonio, Federica\|Saletti, Piercarlo\|De Dosso, Sara\|Mazzucchelli, Luca\|Frattini, Milo\|Siena, Salvatore\|Bardelli, Alberto
PMID:	19223544

217.
Journal:	J Clin Oncol. 2009 Mar 20;27(9):1477-84.
Title:	PIK3CA mutation is associated with poor prognosis among patients with curatively resected colon cancer.
Author:	Ogino, Shuji\|Nosho, Katsuhiko\|Kirkner, Gregory J\|Shima, Kaori\|Irahara, Natsumi\|Kure, Shoko\|Chan, Andrew T\|Engelman, Jeffrey A\|Kraft, Peter\|Cantley, Lewis C\|Giovannucci, Edward L\|Fuchs, Charles S
PMID:	19237633

218.
Journal:	Fam Cancer. 2009;8(4):313-23.
Title:	Analysis of families with Lynch syndrome complicated by advanced serrated neoplasia: the importance of pathology review and pedigree analysis.
Author:	Walsh, Michael D\|Buchanan, Daniel D\|Walters, Rhiannon\|Roberts, Aedan\|Arnold, Sven\|McKeone, Diane\|Clendenning, Mark\|Ruszkiewicz, Andrew R\|Jenkins, Mark A\|Hopper, John L\|Goldblatt, Jack\|George, Jillian\|Suthers, Graeme K\|Phillips, Kerry\|Young, Graeme P\|Macra
PMID:	19241144

219.
Journal:	Br J Cancer. 2009 Apr 7;100(7):1087-94.
Title:	Differing deregulation of EGFR and downstream proteins in primary colorectal cancer and related metastatic sites may be clinically relevant.
Author:	Molinari, F\|Martin, V\|Saletti, P\|De Dosso, S\|Spitale, A\|Camponovo, A\|Bordoni, A\|Crippa, S\|Mazzucchelli, L\|Frattini, M
PMID:	19293803

220.
Journal:	Gastroenterology. 2009 Jul;137(1):176-87.
Title:	Frequent inactivation of axon guidance molecule RGMA in human colon cancer through genetic and epigenetic mechanisms.
Author:	Li, Vivian S W\|Yuen, Siu Tsan\|Chan, Tsun Leung\|Yan, Helen H N\|Law, Wai Lun\|Yeung, Bonnie H Y\|Chan, Annie S Y\|Tsui, Wai Yin\|So, Samuel\|Chen, Xin\|Leung, Suet Yi
PMID:	19303019

221.
Journal:	Cancer Lett. 2009 Aug 28;281(2):162-70.
Title:	Luteolin, quercetin and ursolic acid are potent inhibitors of proliferation and inducers of apoptosis in both KRAS and BRAF mutated human colorectal cancer cells.
Author:	Xavier, Cristina P R\|Lima, Cristovao F\|Preto, Ana\|Seruca, Raquel\|Fernandes-Ferreira, Manuel\|Pereira-Wilson, Cristina
PMID:	19344998

222.
Journal:	Int J Cancer. 2009 Jul 1;125(1):158-64.
Title:	Somatic alterations, metabolizing genes and smoking in rectal cancer.
Author:	Curtin, Karen\|Samowitz, Wade S\|Wolff, Roger K\|Herrick, Jennifer\|Caan, Bette J\|Slattery, Martha L
PMID:	19358278

223.
Journal:	Bioorg Med Chem Lett. 2009 May 15;19(10):2735-8.
Title:	Identification of pyrazolo[1,5-a]pyrimidine-3-carboxylates as B-Raf kinase inhibitors.
Author:	Gopalsamy, Ariamala\|Ciszewski, Greg\|Hu, Yongbo\|Lee, Frederick\|Feldberg, Larry\|Frommer, Eileen\|Kim, Steven\|Collins, Karen\|Wojciechowicz, Donald\|Mallon, Robert
PMID:	19362830

224.
Journal:	Mol Cancer Ther. 2009 Apr;8(4):834-43.
Title:	KRAS/BRAF mutation status and ERK1/2 activation as biomarkers for MEK1/2 inhibitor therapy in colorectal cancer.
Author:	Yeh, Jen Jen\|Routh, Elizabeth D\|Rubinas, Tara\|Peacock, Janie\|Martin, Timothy D\|Shen, Xiang Jun\|Sandler, Robert S\|Kim, Hong Jin\|Keku, Temitope O\|Der, Channing J
PMID:	19372556

225.
Journal:	Int J Cancer. 2009 Jul 15;125(2):297-307.
Title:	Selective inhibition of proliferation in colorectal carcinoma cell lines expressing mutant APC or activated B-Raf.
Author:	Zhang, Hui-Hua\|Walker, Francesca\|Kiflemariam, Sara\|Whitehead, Robert H\|Williams, David\|Phillips, Wayne A\|Mikeska, Thomas\|Dobrovic, Alexander\|Burgess, Antony W
PMID:	19378335

226.
Journal:	Clin Cancer Res. 2009 May 1;15(9):3156-62.
Title:	Utility of p16 immunohistochemistry for the identification of Lynch syndrome.
Author:	Paya, Artemio\|Alenda, Cristina\|Perez-Carbonell, Lucia\|Rojas, Estefania\|Soto, Jose-Luis\|Guillen, Carmen\|Castillejo, Adela\|Barbera, Victor M\|Carrato, Alfredo\|Castells, Antoni\|Llor, Xavier\|Andreu, Montserrat\|Koh, Jim\|Enders, Greg H\|Benlloch, Susana\|Jover, Ro
PMID:	19383812

227.
Journal:	Cell Cycle. 2009 Jul 1;8(13):2122-4. Epub 2009 Jul 9.
Title:	MEK1 mutations, but not ERK2 mutations, occur in melanomas and colon carcinomas, but none in thyroid carcinomas.
Author:	Murugan, Avaniyapuram Kannan\|Dong, Jianli\|Xie, Jingwu\|Xing, Mingzhao
PMID:	19411838

228.
Journal:	Neoplasia. 2009 May;11(5):418-25.
Title:	Aurora-A expression is independently associated with chromosomal instability in colorectal cancer.
Author:	Baba, Yoshifumi\|Nosho, Katsuhiko\|Shima, Kaori\|Irahara, Natsumi\|Kure, Shoko\|Toyoda, Saori\|Kirkner, Gregory J\|Goel, Ajay\|Fuchs, Charles S\|Ogino, Shuji
PMID:	19412426

229.
Journal:	Int J Oncol. 2009 Jun;34(6):1541-7.
Title:	Analysis of a correlation between the BRAF V600E mutation and abnormal DNA mismatch repair in patients with sporadic endometrial cancer.
Author:	Kawaguchi, Makiko\|Yanokura, Megumi\|Banno, Kouji\|Kobayashi, Yusuke\|Kuwabara, Yoshiko\|Kobayashi, Maya\|Nomura, Hiroyuki\|Hirasawa, Akira\|Susumu, Nobuyuki\|Aoki, Daisuke
PMID:	19424571

230.
Journal:	Oncol Rep. 2009 Jun;21(6):1577-83.
Title:	Efficient molecular screening of Lynch syndrome by specific 3' promoter methylation of the MLH1 or BRAF mutation in colorectal cancer with high-frequency microsatellite instability.
Author:	Nakagawa, Hitoshi\|Nagasaka, Takeshi\|Cullings, Harry M\|Notohara, Kenji\|Hoshijima, Naoko\|Young, Joanne\|Lynch, Henry T\|Tanaka, Noriaki\|Matsubara, Nagahide
PMID:	19424639

231.
Journal:	Diagn Mol Pathol. 2009 Jun;18(2):62-71.
Title:	Implementation of novel pyrosequencing assays to screen for common mutations of BRAF and KRAS in a cohort of sporadic colorectal cancers.
Author:	Packham, Deborah\|Ward, Robyn L\|Ap Lin, Vita\|Hawkins, Nicholas J\|Hitchins, Megan P
PMID:	19430299

232.
Journal:	Mod Pathol. 2009 Jul;22(7):922-32.
Title:	SIRT1 histone deacetylase expression is associated with microsatellite instability and CpG island methylator phenotype in colorectal cancer.
Author:	Nosho, Katsuhiko\|Shima, Kaori\|Irahara, Natsumi\|Kure, Shoko\|Firestein, Ron\|Baba, Yoshifumi\|Toyoda, Saori\|Chen, Li\|Hazra, Aditi\|Giovannucci, Edward L\|Fuchs, Charles S\|Ogino, Shuji
PMID:	19430421

233.
Journal:	Am J Dermatopathol. 2009 Jun;31(4):354-63.
Title:	Allelotyping, microsatellite instability, and BRAF mutation analyses in common and atypical melanocytic nevi and primary cutaneous melanomas.
Author:	Uribe, Pablo\|Wistuba, Ignacio I\|Gonzalez, Sergio
PMID:	19461239

234.
Journal:	Clin Cancer Res. 2009 Jun 1;15(11):3663-71.
Title:	DNMT3B expression might contribute to CpG island methylator phenotype in colorectal cancer.
Author:	Nosho, Katsuhiko\|Shima, Kaori\|Irahara, Natsumi\|Kure, Shoko\|Baba, Yoshifumi\|Kirkner, Gregory J\|Chen, Li\|Gokhale, Sumita\|Hazra, Aditi\|Spiegelman, Donna\|Giovannucci, Edward L\|Jaenisch, Rudolf\|Fuchs, Charles S\|Ogino, Shuji
PMID:	19470733

235.
Journal:	Gut. 2009 Sep;58(9):1234-41.
Title:	Concomitant mutations and splice variants in KRAS and BRAF demonstrate complex perturbation of the Ras/Raf signalling pathway in advanced colorectal cancer.
Author:	Seth, R\|Crook, S\|Ibrahem, S\|Fadhil, W\|Jackson, D\|Ilyas, M
PMID:	19474002

236.
Journal:	PLoS One. 2009 May 27;4(5):e5717.
Title:	Combined targeting of BRAF and CRAF or BRAF and PI3K effector pathways is required for efficacy in NRAS mutant tumors.
Author:	Jaiswal, Bijay S\|Janakiraman, Vasantharajan\|Kljavin, Noelyn M\|Eastham-Anderson, Jeffrey\|Cupp, James E\|Liang, Yuxin\|Davis, David P\|Hoeflich, Klaus P\|Seshagiri, Somasekar
PMID:	19492075

237.
Journal:	Cancer Epidemiol Biomarkers Prev. 2009 Jun;18(6):1849-58.
Title:	A cohort study of p27 localization in colon cancer, body mass index, and patient survival.
Author:	Ogino, Shuji\|Shima, Kaori\|Nosho, Katsuhiko\|Irahara, Natsumi\|Baba, Yoshifumi\|Wolpin, Brian M\|Giovannucci, Edward L\|Meyerhardt, Jeffrey A\|Fuchs, Charles S
PMID:	19505918

238.
Journal:	Am J Gastroenterol. 2009 Aug;104(8):2047-56.
Title:	A cohort study of STMN1 expression in colorectal cancer: body mass index and prognosis.
Author:	Ogino, Shuji\|Nosho, Katsuhiko\|Baba, Yoshifumi\|Kure, Shoko\|Shima, Kaori\|Irahara, Natsumi\|Toyoda, Saori\|Chen, Li\|Kirkner, Gregory J\|Wolpin, Brian M\|Chan, Andrew T\|Giovannucci, Edward L\|Fuchs, Charles S
PMID:	19513025

239.
Journal:	Mol Diagn Ther. 2009;13(2):103-14.
Title:	Clinical biomarkers in oncology: focus on colorectal cancer.
Author:	De Roock, Wendy\|Biesmans, Bart\|De Schutter, Jef\|Tejpar, Sabine
PMID:	19537845

240.
Journal:	Clin Cancer Res. 2009 Jul 1;15(13):4431-8.
Title:	A cohort study of cyclin D1 expression and prognosis in 602 colon cancer cases.
Author:	Ogino, Shuji\|Nosho, Katsuhiko\|Irahara, Natsumi\|Kure, Shoko\|Shima, Kaori\|Baba, Yoshifumi\|Toyoda, Saori\|Chen, Li\|Giovannucci, Edward L\|Meyerhardt, Jeffrey A\|Fuchs, Charles S
PMID:	19549773

241.
Journal:	Adv Anat Pathol. 2009 Mar;16(2):79-91.
Title:	Pathologic features and biologic importance of colorectal serrated polyps.
Author:	Vakiani, Efsevia\|Yantiss, Rhonda K
PMID:	19550369

242.
Journal:	Mutat Res. 2009 Nov 2;670(1-2):96-8.
Title:	Genetic pathways to colorectal cancer.
Author:	Lea, Isabel A\|Jackson, Marcus A\|Dunnick, June K
PMID:	19576232

243.
Journal:	Int J Oncol. 2009 Aug;35(2):321-7.
Title:	Chromosomally and microsatellite stable colorectal carcinomas without the CpG island methylator phenotype in a molecular classification.
Author:	Ostwald, Christiane\|Linnebacher, Michael\|Weirich, Volker\|Prall, Friedrich
PMID:	19578746

244.
Journal:	Dis Colon Rectum. 2009 Jun;52(6):1039-45.
Title:	Divergent oncogenic changes influence survival differences between colon and rectal adenocarcinomas.
Author:	Kalady, Matthew F\|Sanchez, Julian A\|Manilich, Elena\|Hammel, Jeff\|Casey, Graham\|Church, James M
PMID:	19581844

245.
Journal:	Mol Carcinog. 2009 Nov;48(11):989-94.
Title:	MSH6 G39E polymorphism and CpG island methylator phenotype in colon cancer.
Author:	Curtin, Karen\|Samowitz, Wade S\|Wolff, Roger K\|Caan, Bette J\|Ulrich, Cornelia M\|Potter, John D\|Slattery, Martha L
PMID:	19582761

246.
Journal:	Clin Cancer Res. 2009 Jul 15;15(14):4665-73.
Title:	Relationship of CDX2 loss with molecular features and prognosis in colorectal cancer.
Author:	Baba, Yoshifumi\|Nosho, Katsuhiko\|Shima, Kaori\|Freed, Ellen\|Irahara, Natsumi\|Philips, Juliet\|Meyerhardt, Jeffrey A\|Hornick, Jason L\|Shivdasani, Ramesh A\|Fuchs, Charles S\|Ogino, Shuji
PMID:	19584150

247.
Journal:	Clin Cancer Res. 2009 Jul 15;15(14):4531-7.
Title:	Down-regulation of epidermal growth factor receptor by selective expansion of a 5'-end regulatory dinucleotide repeat in colon cancer with microsatellite instability.
Author:	Baranovskaya, Svetlana\|Martin, Yolanda\|Alonso, Sergio\|Pisarchuk, Ksenia L\|Falchetti, Mario\|Dai, Yuichi\|Khaldoyanidi, Sophia\|Krajewski, Stan\|Novikova, Inna\|Sidorenko, Yuri S\|Perucho, Manuel\|Malkhosyan, Sergei R
PMID:	19584170

248.
Journal:	Br J Cancer. 2009 Aug 18;101(4):715-21.
Title:	KRAS codon 61, 146 and BRAF mutations predict resistance to cetuximab plus irinotecan in KRAS codon 12 and 13 wild-type metastatic colorectal cancer.
Author:	Loupakis, F\|Ruzzo, A\|Cremolini, C\|Vincenzi, B\|Salvatore, L\|Santini, D\|Masi, G\|Stasi, I\|Canestrari, E\|Rulli, E\|Floriani, I\|Bencardino, K\|Galluccio, N\|Catalano, V\|Tonini, G\|Magnani, M\|Fontanini, G\|Basolo, F\|Falcone, A\|Graziano, F
PMID:	19603018

249.
Journal:	Gan To Kagaku Ryoho. 2009 Jul;36(7):1063-6.
Title:	[Status of components in EGFR-related signal transduction as predictive markers for anti-EGFR antibody therapy in colorectal cancer treatment].
Author:	Shimodaira, Hideki\|Soeda, Hiroshi\|Komine, Keigo\|Ishioka, Chikashi
PMID:	19620792

250.
Journal:	Surgery. 2009 Aug;146(2):227-31.
Title:	Genetic and molecular diversity of colon cancer hepatic metastases.
Author:	Messick, Craig A\|Sanchez, Julian\|Dejulius, Kathryn L\|Church, James M\|Kalady, Matthew F
PMID:	19628078

251.
Journal:	Int J Cancer. 2009 Nov 15;125(10):2332-41.
Title:	Intrinsic resistance to the MEK1/2 inhibitor AZD6244 (ARRY-142886) is associated with weak ERK1/2 signalling and/or strong PI3K signalling in colorectal cancer cell lines.
Author:	Balmanno, Kathryn\|Chell, Simon D\|Gillings, Annette S\|Hayat, Shaista\|Cook, Simon J
PMID:	19637312

252.
Journal:	Int J Cancer. 2009 Nov 1;125(9):2127-35.
Title:	TRAIL receptor upregulation and the implication of KRAS/BRAF mutations in human colon cancer tumors.
Author:	Oikonomou, Eftychia\|Kosmidou, Vivian\|Katseli, Anastasia\|Kothonidis, Konstantinos\|Mourtzoukou, Despina\|Kontogeorgos, George\|Andera, Ladislav\|Zografos, Georgios\|Pintzas, Alexander
PMID:	19637313

253.
Journal:	Anticancer Res. 2009 Aug;29(8):3369-74.
Title:	A novel K-ras mutation in colorectal cancer. A case report and literature review.
Author:	Palmirotta, Raffaele\|Savonarola, Annalisa\|Formica, Vincenzo\|Ludovici, Giorgia\|Del Monte, Girolamo\|Roselli, Mario\|Guadagni, Fiorella
PMID:	19661358

254.
Journal:	Science. 2009 Sep 18;325(5947):1555-9.
Title:	Glucose deprivation contributes to the development of KRAS pathway mutations in tumor cells.
Author:	Yun, Jihye\|Rago, Carlo\|Cheong, Ian\|Pagliarini, Ray\|Angenendt, Philipp\|Rajagopalan, Harith\|Schmidt, Kerstin\|Willson, James K V\|Markowitz, Sandy\|Zhou, Shibin\|Diaz, Luis A Jr\|Velculescu, Victor E\|Lengauer, Christoph\|Kinzler, Kenneth W\|Vogelstein, Bert\|Papado
PMID:	19661383

255.
Journal:	Curr Drug Targets. 2009 Oct;10(10):1033-40.
Title:	Anti-EGFR therapy in colorectal cancer: how to choose the right patient.
Author:	Meriggi, F\|Di Biasi, B\|Abeni, C\|Zaniboni, A
PMID:	19663767

256.
Journal:	Cancer Causes Control. 2009 Nov;20(9):1763-8.
Title:	Microsatellite instability and survival in rectal cancer.
Author:	Samowitz, Wade S\|Curtin, Karen\|Wolff, Roger K\|Tripp, Sheryl R\|Caan, Bette J\|Slattery, Martha L
PMID:	19669908

257.
Journal:	Mol Cancer Res. 2009 Aug;7(8):1244-52.
Title:	Oncogenic activating mutations are associated with local copy gain.
Author:	Modrek, Barmak\|Ge, Lin\|Pandita, Ajay\|Lin, Eva\|Mohan, Sankar\|Yue, Peng\|Guerrero, Steve\|Lin, William M\|Pham, Thinh\|Modrusan, Zora\|Seshagiri, Somasekar\|Stern, Howard M\|Waring, Paul\|Garraway, Levi A\|Chant, John\|Stokoe, David\|Cavet, Guy
PMID:	19671679

258.
Journal:	Cancer Epidemiol. 2009 Aug;33(2):123-9.
Title:	A gene marker panel covering the Wnt and the Ras-Raf-MEK-MAPK signalling pathways allows to detect gene mutations in 80% of early (UICC I) colon cancer stages in humans.
Author:	Scholtka, Bettina\|Schneider, Mandy\|Melcher, Ralph\|Katzenberger, Tiemo\|Friedrich, Daniela\|Berghof-Jager, Kornelia\|Scheppach, Wolfgang\|Steinberg, Pablo
PMID:	19679059

259.
Journal:	Gastroenterology. 2009 Nov;137(5):1609-20.e1-3.
Title:	A prospective cohort study shows unique epigenetic, genetic, and prognostic features of synchronous colorectal cancers.
Author:	Nosho, Katsuhiko\|Kure, Shoko\|Irahara, Natsumi\|Shima, Kaori\|Baba, Yoshifumi\|Spiegelman, Donna\|Meyerhardt, Jeffrey A\|Giovannucci, Edward L\|Fuchs, Charles S\|Ogino, Shuji
PMID:	19686742

260.
Journal:	Clin Cancer Res. 2009 Sep 1;15(17):5528-33.
Title:	Tissue biomarker development in a multicentre trial context: a feasibility study on the PETACC3 stage II and III colon cancer adjuvant treatment trial.
Author:	Bosman, Fred T\|Yan, Pu\|Tejpar, Sabine\|Fiocca, Roberto\|Van Cutsem, Eric\|Kennedy, Richard D\|Dietrich, Daniel\|Roth, Arnaud
PMID:	19690194

261.
Journal:	Carcinogenesis. 2009 Oct;30(10):1670-7.
Title:	Oncogenic Ras, but not (V600E)B-RAF, protects from cholesterol depletion-induced apoptosis through the PI3K/AKT pathway in colorectal cancer cells.
Author:	Calleros, Laura\|Sanchez-Hernandez, Irene\|Baquero, Pablo\|Toro, Maria Jose\|Chiloeches, Antonio
PMID:	19700418

262.
Journal:	J Clin Oncol. 2009 Sep 20;27(27):4591-8.
Title:	Prognostic significance and molecular associations of 18q loss of heterozygosity: a cohort study of microsatellite stable colorectal cancers.
Author:	Ogino, Shuji\|Nosho, Katsuhiko\|Irahara, Natsumi\|Shima, Kaori\|Baba, Yoshifumi\|Kirkner, Gregory J\|Meyerhardt, Jeffrey A\|Fuchs, Charles S
PMID:	19704056

263.
Journal:	Cancer Epidemiol Biomarkers Prev. 2009 Sep;18(9):2513-21.
Title:	p21 expression in colon cancer and modifying effects of patient age and body mass index on prognosis.
Author:	Ogino, Shuji\|Nosho, Katsuhiko\|Shima, Kaori\|Baba, Yoshifumi\|Irahara, Natsumi\|Kirkner, Gregory J\|Hazra, Aditi\|De Vivo, Immaculata\|Giovannucci, Edward L\|Meyerhardt, Jeffrey A\|Fuchs, Charles S
PMID:	19723919

264.
Journal:	Cancer Prev Res (Phila). 2009 Sep;2(9):814-22.
Title:	Concordant DNA methylation in synchronous colorectal carcinomas.
Author:	Konishi, Kazuo\|Shen, Lanlan\|Jelinek, Jaroslav\|Watanabe, Yoshiyuki\|Ahmed, Saira\|Kaneko, Kazuhiro\|Kogo, Mari\|Takano, Toshihumi\|Imawari, Michio\|Hamilton, Stanley R\|Issa, Jean-Pierre J
PMID:	19737982

265.
Journal:	J Natl Cancer Inst. 2009 Oct 7;101(19):1308-24.
Title:	Biomarkers predicting clinical outcome of epidermal growth factor receptor-targeted therapy in metastatic colorectal cancer.
Author:	Siena, Salvatore\|Sartore-Bianchi, Andrea\|Di Nicolantonio, Federica\|Balfour, Julia\|Bardelli, Alberto
PMID:	19738166

266.
Journal:	Am J Surg Pathol. 2009 Dec;33(12):1823-32.
Title:	Beta-catenin nuclear labeling is a common feature of sessile serrated adenomas and correlates with early neoplastic progression after BRAF activation.
Author:	Yachida, Shinichi\|Mudali, Shiyama\|Martin, Sherri A\|Montgomery, Elizabeth A\|Iacobuzio-Donahue, Christine A
PMID:	19745699

267.
Journal:	J Int Med Res. 2009 Jul-Aug;37(4):1038-45.
Title:	Methylation in p14(ARF) is frequently observed in colorectal cancer with low-level microsatellite instability.
Author:	Kominami, K\|Nagasaka, T\|Cullings, H M\|Hoshizima, N\|Sasamoto, H\|Young, J\|Leggett, B A\|Tanaka, N\|Matsubara, N
PMID:	19761686

268.
Journal:	Br J Surg. 2009 Oct;96(10):1196-204.
Title:	Genetic and epigenetic classifications define clinical phenotypes and determine patient outcomes in colorectal cancer.
Author:	Sanchez, J A\|Krumroy, L\|Plummer, S\|Aung, P\|Merkulova, A\|Skacel, M\|DeJulius, K L\|Manilich, E\|Church, J M\|Casey, G\|Kalady, M F
PMID:	19787768

269.
Journal:	Cancer Res. 2009 Oct 1;69(19):7811-8.
Title:	An A13 repeat within the 3'-untranslated region of epidermal growth factor receptor (EGFR) is frequently mutated in microsatellite instability colon cancers and is associated with increased EGFR expression.
Author:	Yuan, Ziqiang\|Shin, Joongho\|Wilson, Andrew\|Goel, Sanjay\|Ling, Yi-He\|Ahmed, Naseem\|Dopeso, Higinio\|Jhawer, Minaxi\|Nasser, Shannon\|Montagna, Cristina\|Fordyce, Kenneth\|Augenlicht, Leonard H\|Aaltonen, Lauri A\|Arango, Diego\|Weber, Thomas K\|Mariadason, John M
PMID:	19789347

270.
Journal:	Cancer Epidemiol Biomarkers Prev. 2009 Oct;18(10):2765-72.
Title:	Vitamin D receptor expression is associated with PIK3CA and KRAS mutations in colorectal cancer.
Author:	Kure, Shoko\|Nosho, Katsuhiko\|Baba, Yoshifumi\|Irahara, Natsumi\|Shima, Kaori\|Ng, Kimmie\|Meyerhardt, Jeffrey A\|Giovannucci, Edward L\|Fuchs, Charles S\|Ogino, Shuji
PMID:	19789368

271.
Journal:	PLoS One. 2009 Oct 2;4(10):e7287.
Title:	Multi-determinants analysis of molecular alterations for predicting clinical benefit to EGFR-targeted monoclonal antibodies in colorectal cancer.
Author:	Sartore-Bianchi, Andrea\|Di Nicolantonio, Federica\|Nichelatti, Michele\|Molinari, Francesca\|De Dosso, Sara\|Saletti, Piercarlo\|Martini, Miriam\|Cipani, Tiziana\|Marrapese, Giovanna\|Mazzucchelli, Luca\|Lamba, Simona\|Veronese, Silvio\|Frattini, Milo\|Bardelli, Albe
PMID:	19806185

272.
Journal:	Clin Cancer Res. 2009 Oct 15;15(20):6412-20.
Title:	Lymphocytic reaction to colorectal cancer is associated with longer survival, independent of lymph node count, microsatellite instability, and CpG island methylator phenotype.
Author:	Ogino, Shuji\|Nosho, Katsuhiko\|Irahara, Natsumi\|Meyerhardt, Jeffrey A\|Baba, Yoshifumi\|Shima, Kaori\|Glickman, Jonathan N\|Ferrone, Cristina R\|Mino-Kenudson, Mari\|Tanaka, Noriko\|Dranoff, Glenn\|Giovannucci, Edward L\|Fuchs, Charles S
PMID:	19825961

273.
Journal:	Cancer Res. 2009 Nov 1;69(21):8499-506.
Title:	Oncogenic KRAS and BRAF differentially regulate hypoxia-inducible factor-1alpha and -2alpha in colon cancer.
Author:	Kikuchi, Hirotoshi\|Pino, Maria S\|Zeng, Min\|Shirasawa, Senji\|Chung, Daniel C
PMID:	19843849

274.
Journal:	Mol Cancer Ther. 2009 Nov;8(11):3009-14.
Title:	Efficacy of IGFBP7 for treatment of metastatic melanoma and other cancers in mouse models and human cell lines.
Author:	Wajapeyee, Narendra\|Kapoor, Varun\|Mahalingam, Meera\|Green, Michael R
PMID:	19861408

275.
Journal:	Neoplasia. 2009 Nov;11(11):1116-31.
Title:	BRAF(V600E) efficient transformation and induction of microsatellite instability versus KRAS(G12V) induction of senescence markers in human colon cancer cells.
Author:	Oikonomou, Eftychia\|Makrodouli, Eleni\|Evagelidou, Maria\|Joyce, Tobias\|Probert, Lesley\|Pintzas, Alexander
PMID:	19881948

276.
Journal:	J Clin Oncol. 2009 Dec 10;27(35):5931-7.
Title:	KRAS and BRAF mutations in advanced colorectal cancer are associated with poor prognosis but do not preclude benefit from oxaliplatin or irinotecan: results from the MRC FOCUS trial.
Author:	Richman, Susan D\|Seymour, Matthew T\|Chambers, Philip\|Elliott, Faye\|Daly, Catherine L\|Meade, Angela M\|Taylor, Graham\|Barrett, Jennifer H\|Quirke, Philip
PMID:	19884549

277.
Journal:	Clin Cancer Res. 2009 Nov 15;15(22):6956-62.
Title:	PIK3CA mutations predict local recurrences in rectal cancer patients.
Author:	He, Youji\|Van't Veer, Laura J\|Mikolajewska-Hanclich, Izabela\|van Velthuysen, Marie-Louise F\|Zeestraten, Eliane C M\|Nagtegaal, Iris D\|van de Velde, Cornelis J H\|Marijnen, Corrie A M
PMID:	19903786

278.
Journal:	Virchows Arch. 2009 Dec;455(6):485-94.
Title:	Prognostic implications of CpG island hypermethylator phenotype in colorectal cancers.
Author:	Kim, Jung Ho\|Shin, So Hyun\|Kwon, Hyeong Ju\|Cho, Nam Yun\|Kang, Gyeong Hoon
PMID:	19911194

279.
Journal:	Cancer Epidemiol Biomarkers Prev. 2009 Dec;18(12):3384-8.
Title:	Assessing tumor mutations to gain insight into base excision repair sequence polymorphisms and smoking in colon cancer.
Author:	Curtin, Karen\|Samowitz, Wade S\|Wolff, Roger K\|Ulrich, Cornelia M\|Caan, Bette J\|Potter, John D\|Slattery, Martha L
PMID:	19959686

280.
Journal:	PLoS One. 2009 Dec 21;4(12):e8357.
Title:	Analysis of the association between CIMP and BRAF in colorectal cancer by DNA methylation profiling.
Author:	Hinoue, Toshinori\|Weisenberger, Daniel J\|Pan, Fei\|Campan, Mihaela\|Kim, Myungjin\|Young, Joanne\|Whitehall, Vicki L\|Leggett, Barbara A\|Laird, Peter W
PMID:	20027224

281.
Journal:	Oncology. 2009;77 Suppl 1:57-68.
Title:	The long and winding road to useful predictive factors for anti-EGFR therapy in metastatic colorectal carcinoma: the KRAS/BRAF pathway.
Author:	Russo, Antonio\|Rizzo, Sergio\|Bronte, Giuseppe\|Silvestris, Nicola\|Colucci, Giuseppe\|Gebbia, Nicola\|Bazan, Viviana\|Fulfaro, Fabio
PMID:	20130433

282.
Journal:	J Oncol. 2009;2009:831626.
Title:	Concordance of KRAS/BRAF Mutation Status in Metastatic Colorectal Cancer before and after Anti-EGFR Therapy.
Author:	Gattenlohner, S\|Etschmann, B\|Kunzmann, V\|Thalheimer, A\|Hack, M\|Kleber, G\|Einsele, H\|Germer, C\|Muller-Hermelink, H-K
PMID:	20300583

283.
Journal:	Ther Adv Med Oncol. 2009 Sep;1(2):55-68.
Title:	Medical treatment of advanced colorectal cancer in 2009.
Author:	Grothey, Axel
PMID:	21789113

284.
Journal:	Carcinogenesis. 2010 Mar;31(3):342-9.
Title:	IGFBP7 is a p53-responsive gene specifically silenced in colorectal cancer with CpG island methylator phenotype.
Author:	Suzuki, Hiromu\|Igarashi, Shinichi\|Nojima, Masanori\|Maruyama, Reo\|Yamamoto, Eiichiro\|Kai, Masahiro\|Akashi, Hirofumi\|Watanabe, Yoshiyuki\|Yamamoto, Hiroyuki\|Sasaki, Yasushi\|Itoh, Fumio\|Imai, Kohzoh\|Sugai, Tamotsu\|Shen, Lanlan\|Issa, Jean-Pierre J\|Shinomura, Y
PMID:	19638426

285.
Journal:	Int J Cancer. 2010 Jun 15;126(12):2863-73.
Title:	CDK8 expression in 470 colorectal cancers in relation to beta-catenin activation, other molecular alterations and patient survival.
Author:	Firestein, Ron\|Shima, Kaori\|Nosho, Katsuhiko\|Irahara, Natsumi\|Baba, Yoshifumi\|Bojarski, Emeric\|Giovannucci, Edward L\|Hahn, William C\|Fuchs, Charles S\|Ogino, Shuji
PMID:	19790197

286.
Journal:	Am J Gastroenterol. 2010 Feb;105(2):420-33.
Title:	Negative lymph node count is associated with survival of colorectal cancer patients, independent of tumoral molecular alterations and lymphocytic reaction.
Author:	Ogino, Shuji\|Nosho, Katsuhiko\|Irahara, Natsumi\|Shima, Kaori\|Baba, Yoshifumi\|Kirkner, Gregory J\|Mino-Kenudson, Mari\|Giovannucci, Edward L\|Meyerhardt, Jeffrey A\|Fuchs, Charles S
PMID:	19809407

287.
Journal:	Cancer Lett. 2010 Apr 1;290(1):24-35.
Title:	Geldanamycin and its anti-cancer activities.
Author:	Fukuyo, Yayoi\|Hunt, Clayton R\|Horikoshi, Nobuo
PMID:	19850405

288.
Journal:	Int J Cancer. 2010 Jul 15;127(2):367-80.
Title:	Clinicopathological and protein characterization of BRAF- and K-RAS-mutated colorectal cancer and implications for prognosis.
Author:	Zlobec, Inti\|Bihl, Michel P\|Schwarb, Heike\|Terracciano, Luigi\|Lugli, Alessandro
PMID:	19908233

289.
Journal:	Radiother Oncol. 2010 Jan;94(1):76-81.
Title:	KRAS and BRAF mutations in patients with rectal cancer treated with preoperative chemoradiotherapy.
Author:	Gaedcke, Jochen\|Grade, Marian\|Jung, Klaus\|Schirmer, Markus\|Jo, Peter\|Obermeyer, Christoph\|Wolff, Hendrik A\|Herrmann, Markus K\|Beissbarth, Tim\|Becker, Heinz\|Ried, Thomas\|Ghadimi, Michael
PMID:	19913317

290.
Journal:	Br J Cancer. 2010 Jan 5;102(1):151-61.
Title:	Prognostic and predictive value of TOPK stratified by KRAS and BRAF gene alterations in sporadic, hereditary and metastatic colorectal cancer patients.
Author:	Zlobec, I\|Molinari, F\|Kovac, M\|Bihl, M P\|Altermatt, H J\|Diebold, J\|Frick, H\|Germer, M\|Horcic, M\|Montani, M\|Singer, G\|Yurtsever, H\|Zettl, A\|Terracciano, L\|Mazzucchelli, L\|Saletti, P\|Frattini, M\|Heinimann, K\|Lugli, A
PMID:	19935791

291.
Journal:	Fam Cancer. 2010 Jun;9(2):167-72.
Title:	Selection of patients with germline MLH1 mutated Lynch syndrome by determination of MLH1 methylation and BRAF mutation.
Author:	Bouzourene, Hanifa\|Hutter, Pierre\|Losi, Lorena\|Martin, Patricia\|Benhattar, Jean
PMID:	19949877

292.
Journal:	Hum Mol Genet. 2010 Feb 15;19(4):697-706.
Title:	Mixed lineage kinase 3 gene mutations in mismatch repair deficient gastrointestinal tumours.
Author:	Velho, Sergia\|Oliveira, Carla\|Paredes, Joana\|Sousa, Sonia\|Leite, Marina\|Matos, Paulo\|Milanezi, Fernanda\|Ribeiro, Ana Sofia\|Mendes, Nuno\|Licastro, Danilo\|Karhu, Auli\|Oliveira, Maria Jose\|Ligtenberg, Marjolijn\|Hamelin, Richard\|Carneiro, Fatima\|Lindblom, Ann
PMID:	19955118

293.
Journal:	J Clin Oncol. 2010 Jan 20;28(3):466-74.
Title:	Prognostic role of KRAS and BRAF in stage II and III resected colon cancer: results of the translational study on the PETACC-3, EORTC 40993, SAKK 60-00 trial.
Author:	Roth, Arnaud D\|Tejpar, Sabine\|Delorenzi, Mauro\|Yan, Pu\|Fiocca, Roberto\|Klingbiel, Dirk\|Dietrich, Daniel\|Biesmans, Bart\|Bodoky, Gyorgy\|Barone, Carlo\|Aranda, Enrique\|Nordlinger, Bernard\|Cisar, Laura\|Labianca, Roberto\|Cunningham, David\|Van Cutsem, Eric\|Bosma
PMID:	20008640

294.
Journal:	Fam Cancer. 2010 Jun;9(2):155-66.
Title:	Mismatch repair protein expression and colorectal cancer in Hispanics from Puerto Rico.
Author:	De Jesus-Monge, Wilfredo E\|Gonzalez-Keelan, Carmen\|Zhao, Ronghua\|Hamilton, Stanley R\|Rodriguez-Bigas, Miguel\|Cruz-Correa, Marcia
PMID:	20012372

295.
Journal:	Clin Cancer Res. 2010 Jan 1;16(1):21-33.
Title:	Three DNA methylation epigenotypes in human colorectal cancer.
Author:	Yagi, Koichi\|Akagi, Kiwamu\|Hayashi, Hiroshi\|Nagae, Genta\|Tsuji, Shingo\|Isagawa, Takayuki\|Midorikawa, Yutaka\|Nishimura, Yoji\|Sakamoto, Hirohiko\|Seto, Yasuyuki\|Aburatani, Hiroyuki\|Kaneda, Atsushi
PMID:	20028768

296.
Journal:	Surgery. 2010 May;147(5):720-8.
Title:	Taiwan hospital-based detection of Lynch syndrome distinguishes 2 types of microsatellite instabilities in colorectal cancers.
Author:	Chang, Shih-Ching\|Lin, Pei-Ching\|Yang, Shung-Haur\|Wang, Huann-Sheng\|Liang, Wen-Yih\|Lin, Jen-Kou
PMID:	20045164

297.
Journal:	Ann Surg Oncol. 2010 May;17(5):1429-34.
Title:	KRAS and BRAF mutational status in primary colorectal tumors and related metastatic sites: biological and clinical implications.
Author:	Italiano, Antoine\|Hostein, Isabelle\|Soubeyran, Isabelle\|Fabas, Thibault\|Benchimol, Daniel\|Evrard, Serge\|Gugenheim, Jean\|Becouarn, Yves\|Brunet, Rene\|Fonck, Marianne\|Francois, Eric\|Saint-Paul, Marie-Christine\|Pedeutour, Florence
PMID:	20049644

298.
Journal:	Br J Cancer. 2010 Feb 2;102(3):482-8.
Title:	Performance of clinical guidelines compared with molecular tumour screening methods in identifying possible Lynch syndrome among colorectal cancer patients: a Norwegian population-based study.
Author:	Trano, G\|Sjursen, W\|Wasmuth, H H\|Hofsli, E\|Vatten, L J
PMID:	20051945

299.
Journal:	Bull Cancer. 2010 Feb;97(2):265-80.
Title:	[Prerequisites to the administration and prevention of adverse effects of chemotherapy in colorectal cancer].
Author:	Bouche, O\|Scaglia, E\|Lagarde, S
PMID:	20080456

300.
Journal:	Curr Cancer Drug Targets. 2010 Feb;10(1):68-79.
Title:	Molecular predictors of efficacy to anti-EGFR agents in colorectal cancer patients.
Author:	Ruzzo, Annamaria\|Graziano, Francesco\|Canestrari, Emanuele\|Magnani, Mauro
PMID:	20088793

301.
Journal:	PLoS One. 2010 Jan 21;5(1):e8802.
Title:	Two multiplex assays that simultaneously identify 22 possible mutation sites in the KRAS, BRAF, NRAS and PIK3CA genes.
Author:	Lurkin, Irene\|Stoehr, Robert\|Hurst, Carolyn D\|van Tilborg, Angela A G\|Knowles, Margaret A\|Hartmann, Arndt\|Zwarthoff, Ellen C
PMID:	20098682

302.
Journal:	J Clin Oncol. 2010 Mar 1;28(7):1254-61.
Title:	Molecular mechanisms of resistance to cetuximab and panitumumab in colorectal cancer.
Author:	Bardelli, Alberto\|Siena, Salvatore
PMID:	20100961

303.
Journal:	Gastroenterology. 2010 May;138(5):1854-62.
Title:	Aberrant DNA methylation in hereditary nonpolyposis colorectal cancer without mismatch repair deficiency.
Author:	Goel, Ajay\|Xicola, Rosa M\|Nguyen, Thuy-Phuong\|Doyle, Brian J\|Sohn, Vanessa R\|Bandipalliam, Prathap\|Rozek, Laura S\|Reyes, Josep\|Cordero, Carmen\|Balaguer, Francesc\|Castells, Antoni\|Jover, Rodrigo\|Andreu, Montserrat\|Syngal, Sapna\|Boland, C Richard\|Llor, Xavi
PMID:	20102720

304.
Journal:	Clin Cancer Res. 2010 Feb 1;16(3):790-9.
Title:	Prevalence and heterogeneity of KRAS, BRAF, and PIK3CA mutations in primary colorectal adenocarcinomas and their corresponding metastases.
Author:	Baldus, Stephan E\|Schaefer, Karl-L\|Engers, Rainer\|Hartleb, Dinah\|Stoecklein, Nikolas H\|Gabbert, Helmut E
PMID:	20103678

305.
Journal:	Oncologist. 2010;15(2):157-67.
Title:	Predicting response to EGFR inhibitors in metastatic colorectal cancer: current practice and future directions.
Author:	Shankaran, Veena\|Obel, Jennifer\|Benson, Al B 3rd
PMID:	20133499

306.
Journal:	J Transl Med. 2010 Feb 10;8:15.
Title:	TAp73 is one of the genes responsible for the lack of response to chemotherapy depending on B-Raf mutational status.
Author:	Herreros-Villanueva, Marta\|Muniz, Pilar\|Garcia-Giron, Carlos\|Cavia-Saiz, Monica\|del Corral, Maria J Coma
PMID:	20146801

307.
Journal:	Int J Cancer. 2010 Dec 1;127(11):2569-75.
Title:	Combined analysis of specific KRAS mutation, BRAF and microsatellite instability identifies prognostic subgroups of sporadic and hereditary colorectal cancer.
Author:	Zlobec, Inti\|Kovac, Michal\|Erzberger, Priska\|Molinari, Francesca\|Bihl, Michel P\|Rufle, Alexander\|Foerster, Anja\|Frattini, Milo\|Terracciano, Luigi\|Heinimann, Karl\|Lugli, Alessandro
PMID:	20162668

308.
Journal:	Cell Commun Signal. 2010 Feb 2;8(1):1.
Title:	High Erk activity suppresses expression of the cell cycle inhibitor p27Kip1 in colorectal cancer cells.
Author:	Kress, Theresia R\|Raabe, Thomas\|Feller, Stephan M
PMID:	20181064

309.
Journal:	Diagn Mol Pathol. 2010 Mar;19(1):1-8.
Title:	Rapid multiplex real-time PCR by molecular beacons for different BRAF allele detection in papillary thyroid carcinoma.
Author:	Orru, Germano\|Coghe, Ferdinando\|Faa, Gavino\|Pillai, Sara\|Manieli, Cristina\|Montaldo, Caterina\|Pilia, Francesca\|Pichiri, Giuseppina\|Piras, Vincenzo\|Coni, Pierpaolo
PMID:	20186005

310.
Journal:	Clin Cancer Res. 2010 Mar 15;16(6):1845-55.
Title:	The role of the CpG island methylator phenotype in colorectal cancer prognosis depends on microsatellite instability screening status.
Author:	Dahlin, Anna M\|Palmqvist, Richard\|Henriksson, Maria L\|Jacobsson, Maria\|Eklof, Vincy\|Rutegard, Jorgen\|Oberg, Ake\|Van Guelpen, Bethany R
PMID:	20197478

311.
Journal:	Cancer Epidemiol Biomarkers Prev. 2010 Mar;19(3):822-31.
Title:	PTGER2 overexpression in colorectal cancer is associated with microsatellite instability, independent of CpG island methylator phenotype.
Author:	Baba, Yoshifumi\|Nosho, Katsuhiko\|Shima, Kaori\|Goessling, Wolfram\|Chan, Andrew T\|Ng, Kimmie\|Chan, Jennifer A\|Giovannucci, Edward L\|Fuchs, Charles S\|Ogino, Shuji
PMID:	20200425

312.
Journal:	Cancer Epidemiol Biomarkers Prev. 2010 Mar;19(3):838-43.
Title:	Smoking, gender, and ethnicity predict somatic BRAF mutations in colorectal cancer.
Author:	Rozek, Laura S\|Herron, Casey M\|Greenson, Joel K\|Moreno, Victor\|Capella, Gabriel\|Rennert, Gad\|Gruber, Stephen B
PMID:	20200438

313.
Journal:	BMC Cancer. 2010 Mar 16;10:99.
Title:	Dietary, lifestyle and clinicopathological factors associated with BRAF and K-ras mutations arising in distinct subsets of colorectal cancers in the EPIC Norfolk study.
Author:	Naguib, Adam\|Mitrou, Panagiota N\|Gay, Laura J\|Cooke, James C\|Luben, Robert N\|Ball, Richard Y\|McTaggart, Alison\|Arends, Mark J\|Rodwell, Sheila A
PMID:	20233436

314.
Journal:	BMC Cancer. 2010 Mar 16;10:101.
Title:	A rapid, sensitive, reproducible and cost-effective method for mutation profiling of colon cancer and metastatic lymph nodes.
Author:	Fumagalli, Debora\|Gavin, Patrick G\|Taniyama, Yusuke\|Kim, Seung-Il\|Choi, Hyun-Joo\|Paik, Soonmyung\|Pogue-Geile, Katherine L
PMID:	20233444

315.
Journal:	Br J Cancer. 2010 Mar 30;102(7):1137-44.
Title:	Mitogen-activated protein kinase phosphatase-1 (MKP-1) impairs the response to anti-epidermal growth factor receptor (EGFR) antibody cetuximab in metastatic colorectal cancer patients.
Author:	Montagut, C\|Iglesias, M\|Arumi, M\|Bellosillo, B\|Gallen, M\|Martinez-Fernandez, A\|Martinez-Aviles, L\|Canadas, I\|Dalmases, A\|Moragon, E\|Lema, L\|Serrano, S\|Rovira, A\|Rojo, F\|Bellmunt, J\|Albanell, J
PMID:	20234366

316.
Journal:	Dig Dis Sci. 2010 Aug;55(8):2352-6.
Title:	Is BRAF mutation associated with interval colorectal cancers?
Author:	Shaukat, Aasma\|Arain, Mustafa\|Thaygarajan, Bharat\|Bond, John H\|Sawhney, Mandeep
PMID:	20300843

317.
Journal:	Am J Pathol. 2010 May;176(5):2292-301.
Title:	HIF1A overexpression is associated with poor prognosis in a cohort of 731 colorectal cancers.
Author:	Baba, Yoshifumi\|Nosho, Katsuhiko\|Shima, Kaori\|Irahara, Natsumi\|Chan, Andrew T\|Meyerhardt, Jeffrey A\|Chung, Daniel C\|Giovannucci, Edward L\|Fuchs, Charles S\|Ogino, Shuji
PMID:	20363910

318.
Journal:	Arch Pathol Lab Med. 2010 Apr;134(4):620-4.
Title:	KRas and BRaf mutational status analysis from formalin-fixed, paraffin-embedded tissues using multiplex polymerase chain reaction-based assay.
Author:	Jakubauskas, Arturas\|Griskevicius, Laimonas
PMID:	20367313

319.
Journal:	Cancer Epidemiol. 2010 Jun;34(3):338-44.
Title:	Polymorphisms in methyl-group metabolism genes and risk of sporadic colorectal cancer with relation to the CpG island methylator phenotype.
Author:	Karpinski, Pawel\|Myszka, Aleksander\|Ramsey, David\|Misiak, Blazej\|Gil, Justyna\|Laczmanska, Izabela\|Grzebieniak, Zygmunt\|Sebzda, Tadeusz\|Smigiel, Robert\|Stembalska, Agnieszka\|Sasiadek, Maria M
PMID:	20381446

320.
Journal:	Oncogene. 2010 May 27;29(21):3033-43.
Title:	Oncogenic mutations as predictive factors in colorectal cancer.
Author:	Lievre, A\|Blons, H\|Laurent-Puig, P
PMID:	20383189

321.
Journal:	Surgeon. 2010 Jun;8(3):164-71.
Title:	Colorectal cancer screening - methodology.
Author:	Jenkinson, F\|Steele, R J C
PMID:	20400027

322.
Journal:	Eur J Cancer. 2010 Jul;46(11):1997-2009.
Title:	Markers for EGFR pathway activation as predictor of outcome in metastatic colorectal cancer patients treated with or without cetuximab.
Author:	Tol, Jolien\|Dijkstra, Jeroen R\|Klomp, Marjolein\|Teerenstra, Steven\|Dommerholt, Martin\|Vink-Borger, M Elisa\|van Cleef, Patricia H\|van Krieken, J Han\|Punt, Cornelis J A\|Nagtegaal, Iris D
PMID:	20413299

323.
Journal:	Eur J Cancer. 2010 Jul;46(10):1823-8.
Title:	Molecular biology from bench-to-bedside - which colorectal cancer patients should be referred for genetic counselling and risk assessment.
Author:	Jensen, Lars Henrik\|Dysager, Lars\|Lindebjerg, Jan\|Kolvra, Steen\|Byriel, Lene\|Cruger, Dorthe Gylling
PMID:	20417091

324.
Journal:	BMC Cancer. 2010 May 5;10:180.
Title:	Early onset MSI-H colon cancer with MLH1 promoter methylation, is there a genetic predisposition?
Author:	van Roon, Eddy H J\|van Puijenbroek, Marjo\|Middeldorp, Anneke\|van Eijk, Ronald\|de Meijer, Emile J\|Erasmus, Dianhdra\|Wouters, Kim A D\|van Engeland, Manon\|Oosting, Jan\|Hes, Frederik J\|Tops, Carli M J\|van Wezel, Tom\|Boer, Judith M\|Morreau, Hans
PMID:	20444249

325.
Journal:	Thyroid. 2010 Jun;20(6):615-22.
Title:	Sulindac reverses aberrant expression and localization of beta-catenin in papillary thyroid cancer cells with the BRAFV600E mutation.
Author:	Cho, Nancy L\|Lin, Chi-Iou\|Whang, Edward E\|Carothers, Adelaide M\|Moore, Francis D Jr\|Ruan, Daniel T
PMID:	20470206

326.
Journal:	J Mol Diagn. 2010 Jul;12(4):498-504.
Title:	Methylation analysis of MLH1 improves the selection of patients for genetic testing in Lynch syndrome.
Author:	Perez-Carbonell, Lucia\|Alenda, Cristina\|Paya, Artemio\|Castillejo, Adela\|Barbera, Victor M\|Guillen, Carmen\|Rojas, Estefania\|Acame, Nuria\|Gutierrez-Avino, Francisco J\|Castells, Antoni\|Llor, Xavier\|Andreu, Montserrat\|Soto, Jose-Luis\|Jover, Rodrigo
PMID:	20489114

327.
Journal:	BMC Cancer. 2010 May 21;10:227.
Title:	Comprehensive profiling of DNA methylation in colorectal cancer reveals subgroups with distinct clinicopathological and molecular features.
Author:	Ang, Pei Woon\|Loh, Marie\|Liem, Natalia\|Lim, Pei Li\|Grieu, Fabienne\|Vaithilingam, Aparna\|Platell, Cameron\|Yong, Wei Peng\|Iacopetta, Barry\|Soong, Richie
PMID:	20492682

328.
Journal:	Nucleic Acids Res. 2010 Oct;38(18):6159-75.
Title:	Origin and quantification of circulating DNA in mice with human colorectal cancer xenografts.
Author:	Thierry, Alain R\|Mouliere, Florent\|Gongora, Celine\|Ollier, Jeremy\|Robert, Bruno\|Ychou, Marc\|Del Rio, Maguy\|Molina, Franck
PMID:	20494973

329.
Journal:	Curr Opin Investig Drugs. 2010 Jun;11(6):699-706.
Title:	PLX-4032, a small-molecule B-Raf inhibitor for the potential treatment of malignant melanoma.
Author:	Smalley, Keiran S M
PMID:	20496265

330.
Journal:	Pol J Pathol. 2010;61(1):23-6.
Title:	BRAF mutations in sporadic colorectal carcinoma from polish patients.
Author:	Wojcik, Piotr\|Okon, Krzysztof\|Osuch, Czeslaw\|Klimkowska, Agnieszka\|Tomaszewska, Romana
PMID:	20496269

331.
Journal:	Ann Oncol. 2010 Dec;21(12):2396-402.
Title:	The BRAF V600E mutation is an independent prognostic factor for survival in stage II and stage III colon cancer patients.
Author:	Farina-Sarasqueta, A\|van Lijnschoten, G\|Moerland, E\|Creemers, G-J\|Lemmens, V E P P\|Rutten, H J T\|van den Brule, A J C
PMID:	20501503

332.
Journal:	Mol Cancer. 2010 May 27;9:125.
Title:	Epigenomic diversity of colorectal cancer indicated by LINE-1 methylation in a database of 869 tumors.
Author:	Baba, Yoshifumi\|Huttenhower, Curtis\|Nosho, Katsuhiko\|Tanaka, Noriko\|Shima, Kaori\|Hazra, Aditi\|Schernhammer, Eva S\|Hunter, David J\|Giovannucci, Edward L\|Fuchs, Charles S\|Ogino, Shuji
PMID:	20507599

333.
Journal:	Cancer J. 2010 May-Jun;16(3):262-72.
Title:	Molecular markers in the treatment of metastatic colorectal cancer.
Author:	Wilson, Peter M\|Labonte, Melissa J\|Lenz, Heinz-Josef
PMID:	20526105

334.
Journal:	Clin Cancer Res. 2010 Jun 15;16(12):3193-204.
Title:	Development of an integrated genomic classifier for a novel agent in colorectal cancer: approach to individualized therapy in early development.
Author:	Pitts, Todd M\|Tan, Aik Choon\|Kulikowski, Gillian N\|Tentler, John J\|Brown, Amy M\|Flanigan, Sara A\|Leong, Stephen\|Coldren, Christopher D\|Hirsch, Fred R\|Varella-Garcia, Marileila\|Korch, Christopher\|Eckhardt, S Gail
PMID:	20530704

335.
Journal:	Cancer Epidemiol Biomarkers Prev. 2010 Jul;19(7):1831-9.
Title:	Increased cancer predisposition in family members of colorectal cancer patients harboring the p.V600E BRAF mutation: a population-based study.
Author:	Wish, Tyler A\|Hyde, Angela J\|Parfrey, Patrick S\|Green, Jane S\|Younghusband, H Banfield\|Simms, Michelle I\|Fontaine, Dan G\|Dicks, Elizabeth L\|Stuckless, Susan N\|Gallinger, Steven\|McLaughlin, John R\|Woods, Michael O\|Green, Roger C
PMID:	20570909

336.
Journal:	Oncologist. 2010;15(7):699-731.
Title:	A review of the most promising biomarkers in colorectal cancer: one step closer to targeted therapy.
Author:	Deschoolmeester, Vanessa\|Baay, Marc\|Specenier, Pol\|Lardon, Filip\|Vermorken, Jan B
PMID:	20584808

337.
Journal:	J Natl Cancer Inst. 2010 Jul 21;102(14):1012-22.
Title:	Cigarette smoking and colorectal cancer risk by molecularly defined subtypes.
Author:	Limsui, David\|Vierkant, Robert A\|Tillmans, Lori S\|Wang, Alice H\|Weisenberger, Daniel J\|Laird, Peter W\|Lynch, Charles F\|Anderson, Kristin E\|French, Amy J\|Haile, Robert W\|Harnack, Lisa J\|Potter, John D\|Slager, Susan L\|Smyrk, Thomas C\|Thibodeau, Stephen N\|Ce
PMID:	20587792

338.
Journal:	J Med Chem. 2010 Aug 12;53(15):5639-55.
Title:	Novel hinge binder improves activity and pharmacokinetic properties of BRAF inhibitors.
Author:	Zambon, Alfonso\|Menard, Delphine\|Suijkerbuijk, Bart M J M\|Niculescu-Duvaz, Ion\|Whittaker, Steven\|Niculescu-Duvaz, Dan\|Nourry, Arnaud\|Davies, Lawrence\|Manne, Helen A\|Lopes, Filipa\|Preece, Natasha\|Hedley, Douglas\|Ogilvie, Lesley M\|Kirk, Ruth\|Marais, Richard
PMID:	20597484

339.
Journal:	Proc Natl Acad Sci U S A. 2010 Jul 13;107(28):12605-10.
Title:	T cell-engaging BiTE antibodies specific for EGFR potently eliminate KRAS- and BRAF-mutated colorectal cancer cells.
Author:	Lutterbuese, Ralf\|Raum, Tobias\|Kischel, Roman\|Hoffmann, Patrick\|Mangold, Susanne\|Rattel, Benno\|Friedrich, Matthias\|Thomas, Oliver\|Lorenczewski, Grit\|Rau, Doris\|Schaller, Evelyne\|Herrmann, Ines\|Wolf, Andreas\|Urbig, Thomas\|Baeuerle, Patrick A\|Kufer, Peter
PMID:	20616015

340.
Journal:	J Mol Diagn. 2010 Sep;12(5):705-11.
Title:	The use of COLD-PCR and high-resolution melting analysis improves the limit of detection of KRAS and BRAF mutations in colorectal cancer.
Author:	Mancini, Irene\|Santucci, Claudio\|Sestini, Roberta\|Simi, Lisa\|Pratesi, Nicola\|Cianchi, Fabio\|Valanzano, Rosa\|Pinzani, Pamela\|Orlando, Claudio
PMID:	20616366

341.
Journal:	Transl Res. 2010 Aug;156(2):98-105.
Title:	Cycleave polymerase chain reaction method is practically applicable for V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog (KRAS)/V-raf murine sarcoma viral oncogene homolog B1 (BRAF) genotyping in colorectal cancer.
Author:	Yokota, Tomoya\|Shibata, Noriko\|Ura, Takashi\|Takahari, Daisuke\|Shitara, Kohei\|Muro, Kei\|Yatabe, Yasushi
PMID:	20627194

342.
Journal:	Clin Colorectal Cancer. 2010 Jun;9 Suppl 1:S16-27.
Title:	Integrating biomarkers into clinical decision making for colorectal cancer.
Author:	Wilson, Peter M\|Lenz, Heinz-Josef
PMID:	20630847

343.
Journal:	Anticancer Drugs. 2010 Sep;21(8):737-48.
Title:	Targeted therapy in advanced colorectal cancer: more data, more questions.
Author:	Ochenduszko, Sebastian L\|Krzemieniecki, Krzysztof
PMID:	20631611

344.
Journal:	Anticancer Res. 2010 Jun;30(6):1969-75.
Title:	KRAS and BRAF mutation analysis from liquid-based cytology brushings of colorectal carcinoma in comparison with formalin-fixed, paraffin-embedded tissue.
Author:	Spathis, Aris\|Georgoulakis, John\|Foukas, Periklis\|Kefala, Maria\|Leventakos, Konstantinos\|Machairas, Anastasios\|Panayiotides, Ioannis\|Karakitsos, Petros
PMID:	20651341

345.
Journal:	Anat Rec (Hoboken). 2010 Sep;293(9):1506-11.
Title:	Gene mutations in epidermal growth factor receptor signaling network and their association with survival in Chinese patients with metastatic colorectal cancers.
Author:	Liao, Wangjun\|Liao, Yulin\|Zhou, Jeff X\|Xie, Jianming\|Chen, Jinzhang\|Huang, Weizhen\|Luo, Rongcheng
PMID:	20652941

346.
Journal:	Clin Gastroenterol Hepatol. 2010 Nov;8(11):966-71.
Title:	Low frequency of Lynch syndrome among young patients with non-familial colorectal cancer.
Author:	Goel, Ajay\|Nagasaka, Takeshi\|Spiegel, Jennifer\|Meyer, Richard\|Lichliter, Warren E\|Boland, C Richard
PMID:	20655395

347.
Journal:	Int J Oncol. 2010 Sep;37(3):707-18.
Title:	Characterization of rectal, proximal and distal colon cancers based on clinicopathological, molecular and protein profiles.
Author:	Minoo, P\|Zlobec, I\|Peterson, M\|Terracciano, L\|Lugli, A
PMID:	20664940

348.
Journal:	Arch Pathol Lab Med. 2010 Aug;134(8):1225-8.
Title:	BRAF mutation testing in colorectal cancer.
Author:	Sharma, Shree G\|Gulley, Margaret L
PMID:	20670148

349.
Journal:	Gastroenterology. 2010 Dec;139(6):1855-64.
Title:	Hypomethylation of the IGF2 DMR in colorectal tumors, detected by bisulfite pyrosequencing, is associated with poor prognosis.
Author:	Baba, Yoshifumi\|Nosho, Katsuhiko\|Shima, Kaori\|Huttenhower, Curtis\|Tanaka, Noriko\|Hazra, Aditi\|Giovannucci, Edward L\|Fuchs, Charles S\|Ogino, Shuji
PMID:	20682317

350.
Journal:	Gut. 2010 Oct;59(10):1369-77.
Title:	The genetic basis of colorectal cancer in a population-based incident cohort with a high rate of familial disease.
Author:	Woods, M O\|Younghusband, H B\|Parfrey, P S\|Gallinger, S\|McLaughlin, J\|Dicks, E\|Stuckless, S\|Pollett, A\|Bapat, B\|Mrkonjic, M\|de la Chapelle, A\|Clendenning, M\|Thibodeau, S N\|Simms, M\|Dohey, A\|Williams, P\|Robb, D\|Searle, C\|Green, J S\|Green, R C
PMID:	20682701

351.
Journal:	BMC Cancer. 2010 Aug 9;10:413.
Title:	Mutations in the WTX-gene are found in some high-grade microsatellite instable (MSI-H) colorectal cancers.
Author:	Scheel, Silvio K\|Porzner, Marc\|Pfeiffer, Sabine\|Ormanns, Steffen\|Kirchner, Thomas\|Jung, Andreas
PMID:	20696052

352.
Journal:	Ann Surg Oncol. 2010 Dec;17(12):3370-8.
Title:	Improved testing for microsatellite instability in colorectal cancer using a simplified 3-marker assay.
Author:	Esemuede, Iyare\|Forslund, Ann\|Khan, Sajid A\|Qin, Li-Xuan\|Gimbel, Mark I\|Nash, Garrett M\|Zeng, Zhaoshi\|Rosenberg, Shoshana\|Shia, Jinru\|Barany, Francis\|Paty, Philip B
PMID:	20703819

353.
Journal:	J Clin Oncol. 2010 Sep 20;28(27):4240-6.
Title:	Randomized, phase II study of the insulin-like growth factor-1 receptor inhibitor IMC-A12, with or without cetuximab, in patients with cetuximab- or panitumumab-refractory metastatic colorectal cancer.
Author:	Reidy, Diane Lauren\|Vakiani, Efsevia\|Fakih, Marwan G\|Saif, Muhammad Wasif\|Hecht, Joel Randolph\|Goodman-Davis, Noah\|Hollywood, Ellen\|Shia, Jinru\|Schwartz, Jonathan\|Chandrawansa, Kumari\|Dontabhaktuni, Aruna\|Youssoufian, Hagop\|Solit, David B\|Saltz, Leonard B
PMID:	20713879

354.
Journal:	Curr Cancer Drug Targets. 2010 Dec;10(8):813-23.
Title:	KRAS mutation testing of colorectal cancer for anti-EGFR therapy: dogmas versus evidence.
Author:	Timar, Jozsef\|Hegedus, Balazs\|Raso, Erzsebet
PMID:	20718705

355.
Journal:	Curr Cancer Drug Targets. 2010 Dec;10(8):799-812.
Title:	Predictive molecular markers of response to epidermal growth factor receptor(EGFR) family-targeted therapies.
Author:	Barton, Sarah\|Starling, Naureen\|Swanton, Charles
PMID:	20718710

356.
Journal:	Clin Adv Hematol Oncol. 2010 Jun;8(6):437-44.
Title:	BRAF testing in advanced colorectal cancer: is it ready for prime time?
Author:	Phillips, Brooke\|Kalady, Matthew\|Kim, Richard
PMID:	20733556

357.
Journal:	Diagn Mol Pathol. 2010 Sep;19(3):157-63.
Title:	NRAS mutations are rare in colorectal cancer.
Author:	Irahara, Natsumi\|Baba, Yoshifumi\|Nosho, Katsuhiko\|Shima, Kaori\|Yan, Liying\|Dias-Santagata, Dora\|Iafrate, Anthony John\|Fuchs, Charles S\|Haigis, Kevin M\|Ogino, Shuji
PMID:	20736745

358.
Journal:	Br J Cancer. 2010 Sep 28;103(7):1025-33.
Title:	Prognostic significance of AMP-activated protein kinase expression and modifying effect of MAPK3/1 in colorectal cancer.
Author:	Baba, Y\|Nosho, K\|Shima, K\|Meyerhardt, J A\|Chan, A T\|Engelman, J A\|Cantley, L C\|Loda, M\|Giovannucci, E\|Fuchs, C S\|Ogino, S
PMID:	20808308

359.
Journal:	Cancer Epidemiol Biomarkers Prev. 2010 Nov;19(11):2777-85.
Title:	Cathepsin B expression and survival in colon cancer: implications for molecular detection of neoplasia.
Author:	Chan, Andrew T\|Baba, Yoshifumi\|Shima, Kaori\|Nosho, Katsuhiko\|Chung, Daniel C\|Hung, Kenneth E\|Mahmood, Umar\|Madden, Karen\|Poss, Kirtland\|Ranieri, Audrey\|Shue, Daniel\|Kucherlapati, Raju\|Fuchs, Charles S\|Ogino, Shuji
PMID:	20833970

360.
Journal:	Mol Cancer Ther. 2010 Dec;9(12):3351-62.
Title:	Identification of predictive markers of response to the MEK1/2 inhibitor selumetinib (AZD6244) in K-ras-mutated colorectal cancer.
Author:	Tentler, John J\|Nallapareddy, Sujatha\|Tan, Aik Choon\|Spreafico, Anna\|Pitts, Todd M\|Morelli, M Pia\|Selby, Heather M\|Kachaeva, Maria I\|Flanigan, Sara A\|Kulikowski, Gillian N\|Leong, Stephen\|Arcaroli, John J\|Messersmith, Wells A\|Eckhardt, S Gail
PMID:	20923857

361.
Journal:	Clin Cancer Res. 2010 Nov 15;16(22):5402-13.
Title:	MSH6 and MUTYH deficiency is a frequent event in early-onset colorectal cancer.
Author:	Giraldez, Maria Dolores\|Balaguer, Francesc\|Bujanda, Luis\|Cuatrecasas, Miriam\|Munoz, Jenifer\|Alonso-Espinaco, Virginia\|Larzabal, Mikel\|Petit, Anna\|Gonzalo, Victoria\|Ocana, Teresa\|Moreira, Leticia\|Enriquez-Navascues, Jose Maria\|Boland, C Richard\|Goel, Ajay\|
PMID:	20924129

362.
Journal:	J Pathol. 2010 Dec;222(4):350-66.
Title:	Tumour-infiltrating T-cell subsets, molecular changes in colorectal cancer, and prognosis: cohort study and literature review.
Author:	Nosho, Katsuhiko\|Baba, Yoshifumi\|Tanaka, Noriko\|Shima, Kaori\|Hayashi, Marika\|Meyerhardt, Jeffrey A\|Giovannucci, Edward\|Dranoff, Glenn\|Fuchs, Charles S\|Ogino, Shuji
PMID:	20927778

363.
Journal:	Expert Rev Gastroenterol Hepatol. 2010 Oct;4(5):525-9.
Title:	Colorectal cancer: cetuximab, KRAS, BRAF, PIK3CA mutations and beyond.
Author:	Katsios, Christos\|Ziogas, Dimosthenis E\|Roukos, Dimitrios H
PMID:	20932136

364.
Journal:	Mol Cancer. 2010 Oct 13;9:271.
Title:	The serine protease inhibitor serpinE2 is a novel target of ERK signaling involved in human colorectal tumorigenesis.
Author:	Bergeron, Sebastien\|Lemieux, Etienne\|Durand, Veronique\|Cagnol, Sebastien\|Carrier, Julie C\|Lussier, Jacques G\|Boucher, Marie-Josee\|Rivard, Nathalie
PMID:	20942929

365.
Journal:	Am J Pathol. 2010 Nov;177(5):2347-56.
Title:	Development of sporadic microsatellite instability in colorectal tumors involves hypermethylation at methylated-in-tumor loci in adenoma.
Author:	de Maat, Michiel F G\|Narita, Norihiko\|Benard, Anne\|Yoshimura, Tetsunori\|Kuo, Christine\|Tollenaar, Rob A E M\|de Miranda, Noel F C C\|Turner, Roderick R\|van de Velde, Cornelis J H\|Morreau, Hans\|Hoon, Dave S B
PMID:	20952593

366.
Journal:	PLoS Curr. 2010 Oct 19;2:RRN1187.
Title:	BRAF p.Val600Glu (V600E) Testing for Assessment of Treatment Options in Metastatic Colorectal Cancer.
Author:	Lea, Andrew\|Allingham-Hawkins, Diane\|Levine, Susan
PMID:	20972475

367.
Journal:	BMC Cancer. 2010 Oct 27;10:587.
Title:	Colorectal carcinomas with microsatellite instability display a different pattern of target gene mutations according to large bowel site of origin.
Author:	Pinheiro, Manuela\|Ahlquist, Terje\|Danielsen, Stine A\|Lind, Guro E\|Veiga, Isabel\|Pinto, Carla\|Costa, Vera\|Afonso, Luis\|Sousa, Olga\|Fragoso, Maria\|Santos, Lucio\|Henrique, Rui\|Lopes, Paula\|Lopes, Carlos\|Lothe, Ragnhild A\|Teixeira, Manuel R
PMID:	20979647

368.
Journal:	Am J Pathol. 2010 Dec;177(6):2731-40.
Title:	Novel application of structural equation modeling to correlation structure analysis of CpG island methylation in colorectal cancer.
Author:	Tanaka, Noriko\|Huttenhower, Curtis\|Nosho, Katsuhiko\|Baba, Yoshifumi\|Shima, Kaori\|Quackenbush, John\|Haigis, Kevin M\|Giovannucci, Edward\|Fuchs, Charles S\|Ogino, Shuji
PMID:	21037082

369.
Journal:	J Cell Biochem. 2010 Dec 1;111(5):1082-6.
Title:	Activation of signal pathways and the resistance to anti-EGFR treatment in colorectal cancer.
Author:	Chen, Jiezhong\|Huang, Xu-Feng\|Katsifis, Andrew
PMID:	21053280

370.
Journal:	Duodecim. 2010;126(17):2002-11.
Title:	[Colorectal serrated lesions: current insight on their role in colorectal carcinogenesis].
Author:	Makinen, Markus
PMID:	21053517

371.
Journal:	Sci Signal. 2010 Nov 23;3(149):ra84.
Title:	BRAF gene amplification can promote acquired resistance to MEK inhibitors in cancer cells harboring the BRAF V600E mutation.
Author:	Corcoran, Ryan B\|Dias-Santagata, Dora\|Bergethon, Kristin\|Iafrate, A John\|Settleman, Jeffrey\|Engelman, Jeffrey A
PMID:	21098728

372.
Journal:	PLoS One. 2010 Nov 12;5(11):e13978.
Title:	DNA sequence profiles of the colorectal cancer critical gene set KRAS-BRAF-PIK3CA-PTEN-TP53 related to age at disease onset.
Author:	Berg, Marianne\|Danielsen, Stine A\|Ahlquist, Terje\|Merok, Marianne A\|Agesen, Trude H\|Vatn, Morten H\|Mala, Tom\|Sjo, Ole H\|Bakka, Arne\|Moberg, Ingvild\|Fetveit, Torunn\|Mathisen, Oystein\|Husby, Anders\|Sandvik, Oddvar\|Nesbakken, Arild\|Thiis-Evensen, Espen\|Lothe
PMID:	21103049

373.
Journal:	Cancer Treat Rev. 2010 Nov;36 Suppl 3:S56-61.
Title:	Prognostic vs predictive molecular biomarkers in colorectal cancer: is KRAS and BRAF wild type status required for anti-EGFR therapy?
Author:	Rizzo, Sergio\|Bronte, Giuseppe\|Fanale, Daniele\|Corsini, Lidia\|Silvestris, Nicola\|Santini, Daniele\|Gulotta, Gaspare\|Bazan, Viviana\|Gebbia, Nicola\|Fulfaro, Fabio\|Russo, Antonio
PMID:	21129611

374.
Journal:	Br J Cancer. 2010 Dec 7;103(12):1765-72.
Title:	Molecular determinants of anti-EGFR sensitivity and resistance in metastatic colorectal cancer.
Author:	Di Fiore, F\|Sesboue, R\|Michel, P\|Sabourin, J C\|Frebourg, T
PMID:	21139621

375.
Journal:	Int J Biol Markers. 2010 Oct-Dec;25(4):179-84.
Title:	Mutation analysis of BRAF exon 15 and KRAS codons 12 and 13 in Moroccan patients with colorectal cancer.
Author:	Bennani, Bahia\|Gilles, Sophie\|Fina, Frederic\|Nanni, Isabelle\|Ibrahimi, Sidi Adil\|Riffi, Afaf Amarti\|Nejjari, Chakib\|Benajeh, Dafr-Allah\|El Abkari, Mohammed\|Martin, Pierre-Marie\|Ouafik, L'Houcine
PMID:	21161938

376.
Journal:	Magy Onkol. 2010 Dec;54(4):383-94.
Title:	Predictive and prognostic factors in the complex treatment of patients with colorectal cancer.
Author:	Laszlo, Landherr
PMID:	21163770

377.
Journal:	Bull Cancer. 2010 Dec;97(12):1441-52.
Title:	[Clinical significance of BRAF mutations in colorectal cancer].
Author:	Lievre, A\|Rouleau, E\|Buecher, B\|Mitry, E
PMID:	21220223

378.
Journal:	Oncology. 2010;79(5-6):415-22.
Title:	Cetuximab plus FOLFOX-4 in untreated patients with advanced colorectal cancer: a Gruppo Oncologico dell'Italia Meridionale Multicenter phase II study.
Author:	Colucci, Giuseppe\|Giuliani, Francesco\|Garufi, Carlo\|Mattioli, Rodolfo\|Manzione, Luigi\|Russo, Antonio\|Lopez, Massimo\|Parrella, Paola\|Tommasi, Stefania\|Copetti, Massimiliano\|Daniele, Bruno\|Pisconti, Salvatore\|Tuveri, Guido\|Silvestris, Nicola\|Maiello, Evaris
PMID:	21474966

379.
Journal:	Cancers (Basel). 2010 Dec 29;3(1):91-105.
Title:	Detection of up to 65% of Precancerous Lesions of the Human Colon and Rectum by Mutation Analysis of APC, K-Ras, B-Raf and CTNNB1.
Author:	Schneider, Mandy\|Scholtka, Bettina\|Gottschalk, Uwe\|Faiss, Siegbert\|Schatz, Daniela\|Berghof-Jager, Kornelia\|Steinberg, Pablo
PMID:	24212608

380.
Journal:	Int J Cancer. 2011 Mar 1;128(5):1080-94.
Title:	Prognostic significance of CDKN2A (p16) promoter methylation and loss of expression in 902 colorectal cancers: Cohort study and literature review.
Author:	Shima, Kaori\|Nosho, Katsuhiko\|Baba, Yoshifumi\|Cantor, Mami\|Meyerhardt, Jeffrey A\|Giovannucci, Edward L\|Fuchs, Charles S\|Ogino, Shuji
PMID:	20473920

381.
Journal:	Mol Biol Rep. 2011 Feb;38(2):1315-20.
Title:	KRAS, BRAF, EGFR and HER2 gene status in a Spanish population of colorectal cancer.
Author:	Herreros-Villanueva, Marta\|Rodrigo, Maximiliano\|Claver, Manuel\|Muniz, Pilar\|Lastra, Enrique\|Garcia-Giron, Carlos\|Coma del Corral, Maria Jesus
PMID:	20563851

382.
Journal:	Mol Biol Rep. 2011 Feb;38(2):1347-51.
Title:	PIK3CA mutations in KRAS and BRAF wild type colorectal cancer patients. A study of Spanish population.
Author:	Herreros-Villanueva, Marta\|Gomez-Manero, Noemi\|Muniz, Pilar\|Garcia-Giron, Carlos\|Coma del Corral, Maria Jesus
PMID:	20571907

383.
Journal:	Int J Cancer. 2011 May 1;128(9):2075-84.
Title:	Optimizing targeted therapeutic development: analysis of a colorectal cancer patient population with the BRAF(V600E) mutation.
Author:	Tie, Jeanne\|Gibbs, Peter\|Lipton, Lara\|Christie, Michael\|Jorissen, Robert N\|Burgess, Antony W\|Croxford, Matthew\|Jones, Ian\|Langland, Rachel\|Kosmider, Suzanne\|McKay, Daniel\|Bollag, Gideon\|Nolop, Keith\|Sieber, Oliver M\|Desai, Jayesh
PMID:	20635392

384.
Journal:	Med Oncol. 2011 Dec;28(4):1048-53.
Title:	Distribution of some activating KRAS and BRAF mutations in Slovene patients with colorectal cancer.
Author:	Licar, Alenka\|Cerkovnik, Petra\|Novakovic, Srdjan
PMID:	20645028

385.
Journal:	Int J Colorectal Dis. 2011 Feb;26(2):127-33.
Title:	Signet-ring cell carcinoma of colorectum--current perspectives and molecular biology.
Author:	Gopalan, Vinod\|Smith, Robert Anthony\|Ho, Yik-Hong\|Lam, Alfred King-Yin
PMID:	20686774

386.
Journal:	Clin Genet. 2011 May;79(5):468-74.
Title:	Germline mutation in BRAF codon 600 is compatible with human development: de novo p.V600G mutation identified in a patient with CFC syndrome.
Author:	Champion, K J\|Bunag, C\|Estep, A L\|Jones, J R\|Bolt, C H\|Rogers, R C\|Rauen, K A\|Everman, D B
PMID:	20735442

387.
Journal:	Int J Cancer. 2011 Jun 15;128(12):2938-46.
Title:	EGFR and HER3 mRNA expression levels predict distant metastases in locally advanced rectal cancer.
Author:	Ho-Pun-Cheung, Alexandre\|Assenat, Eric\|Bascoul-Mollevi, Caroline\|Bibeau, Frederic\|Boissiere-Michot, Florence\|Cellier, Dominic\|Azria, David\|Rouanet, Philippe\|Senesse, Pierre\|Ychou, Marc\|Lopez-Crapez, Evelyne
PMID:	20824716

388.
Journal:	Cytopathology. 2011 Dec;22(6):358-64.
Title:	KRAS and BRAF mutation analysis can be reliably performed on aspirated cytological specimens of metastatic colorectal carcinoma.
Author:	Pang, N K B\|Nga, M E\|Chin, S Y\|Ismail, T M\|Lim, G L\|Soong, R\|Salto-Tellez, M
PMID:	21029218

389.
Journal:	Gut. 2011 Mar;60(3):397-411.
Title:	Molecular pathological epidemiology of colorectal neoplasia: an emerging transdisciplinary and interdisciplinary field.
Author:	Ogino, Shuji\|Chan, Andrew T\|Fuchs, Charles S\|Giovannucci, Edward
PMID:	21036793

390.
Journal:	Cancer Biol Ther. 2011 Jan 15;11(2):177-83. Epub 2011 Jan 15.
Title:	Co-expression of matrix metalloproteinase-7 (MMP-7) and phosphorylated insulin growth factor receptor I (pIGF-1R) correlates with poor prognosis in patients with wild-type KRAS treated with cetuximab or panitumumab: a GEMCAD study.
Author:	Horndler, Carlos\|Gallego, Rosa\|Garcia-Albeniz, Xabier\|Alonso-Espinaco, Virginia\|Alonso, Vicente\|Escudero, Pilar\|Jimeno, Mireya\|Ortego, Javier\|Codony-Servat, Jordi\|Fernandez-Martos, Carlos\|Calatrava, Ana\|Marin-Aguilera, Mercedes\|Munoz, Jenifer\|Castellvi-Be
PMID:	21099348

391.
Journal:	Mod Pathol. 2011 Mar;24(3):396-411.
Title:	Methylation of the 3p22 region encompassing MLH1 is representative of the CpG island methylator phenotype in colorectal cancer.
Author:	Wong, Justin J-L\|Hawkins, Nicholas J\|Ward, Robyn L\|Hitchins, Megan P
PMID:	21102416

392.
Journal:	Tumour Biol. 2011 Apr;32(2):417-24.
Title:	Serum matrilysin correlates with poor survival independently of KRAS and BRAF status in refractory advanced colorectal cancer patients treated with irinotecan plus cetuximab.
Author:	Garcia-Albeniz, Xabier\|Pericay, Carles\|Alonso-Espinaco, Virginia\|Alonso, Vicente\|Escudero, Pilar\|Fernandez-Martos, Carlos\|Gallego, Rosa\|Gascon, Pere\|Castellvi-Bel, Sergi\|Maurel, Joan
PMID:	21104178

393.
Journal:	Hum Pathol. 2011 Mar;42(3):332-9.
Title:	Gene-environment interactions in the pre-Industrial Era: the cancer of King Ferrante I of Aragon (1431-1494).
Author:	Ottini, Laura\|Falchetti, Mario\|Marinozzi, Silvia\|Angeletti, Luciana Rita\|Fornaciari, Gino
PMID:	21111451

394.
Journal:	Cancer Causes Control. 2011 Feb;22(2):301-9.
Title:	MGMT promoter methylation, loss of expression and prognosis in 855 colorectal cancers.
Author:	Shima, Kaori\|Morikawa, Teppei\|Baba, Yoshifumi\|Nosho, Katsuhiko\|Suzuki, Maiko\|Yamauchi, Mai\|Hayashi, Marika\|Giovannucci, Edward\|Fuchs, Charles S\|Ogino, Shuji
PMID:	21140203

395.
Journal:	Cancer Sci. 2011 Jan;102(1):18-24.
Title:	Two groups of DNA methylation markers to classify colorectal cancer into three epigenotypes.
Author:	Kaneda, Atsushi\|Yagi, Koichi
PMID:	21159060

396.
Journal:	Lancet Oncol. 2011 Jun;12(6):594-603.
Title:	KRAS, BRAF, PIK3CA, and PTEN mutations: implications for targeted therapies in metastatic colorectal cancer.
Author:	De Roock, Wendy\|De Vriendt, Veerle\|Normanno, Nicola\|Ciardiello, Fortunato\|Tejpar, Sabine
PMID:	21163703

397.
Journal:	Oncol Rep. 2011 Mar;25(3):789-94.
Title:	Effect of classification based on combination of mutation and methylation in colorectal cancer prognosis.
Author:	Aoyagi, Haruhiko\|Iida, Satoru\|Uetake, Hiroyuki\|Ishikawa, Toshiaki\|Takagi, Yoko\|Kobayashi, Hirotoshi\|Higuchi, Tetsuro\|Yasuno, Masamichi\|Enomoto, Masayuki\|Sugihara, Kenichi
PMID:	21174064

398.
Journal:	Mol Cancer Ther. 2011 Mar;10(3):558-65.
Title:	PIK3CA mutations in patients with advanced cancers treated with PI3K/AKT/mTOR axis inhibitors.
Author:	Janku, Filip\|Tsimberidou, Apostolia M\|Garrido-Laguna, Ignacio\|Wang, Xuemei\|Luthra, Rajyalakshmi\|Hong, David S\|Naing, Aung\|Falchook, Gerald S\|Moroney, John W\|Piha-Paul, Sarina A\|Wheler, Jennifer J\|Moulder, Stacy L\|Fu, Siqing\|Kurzrock, Razelle
PMID:	21216929

399.
Journal:	J Mol Diagn. 2011 Jan;13(1):64-73.
Title:	Detection of KRAS and BRAF mutations in colorectal carcinoma roles for high-sensitivity locked nucleic acid-PCR sequencing and broad-spectrum mass spectrometry genotyping.
Author:	Arcila, Maria\|Lau, Christopher\|Nafa, Khedoudja\|Ladanyi, Marc
PMID:	21227396

400.
Journal:	J Natl Compr Canc Netw. 2011 Jan;9(1):13-25.
Title:	Personalized medicine and oncology practice guidelines: a case study of contemporary biomarkers in colorectal cancer.
Author:	Kelley, Robin K\|Van Bebber, Stephanie L\|Phillips, Kathryn A\|Venook, Alan P
PMID:	21233242

401.
Journal:	Virchows Arch. 2011 Feb;458(2):213-9.
Title:	Downregulation of the hedgehog receptor PTCH1 in colorectal serrated adenocarcinomas is not caused by PTCH1 mutations.
Author:	Stefanius, Karoliina\|Kantola, Tiina\|Tuomisto, Anne\|Vahteristo, Pia\|Karttunen, Tuomo J\|Aaltonen, Lauri A\|Makinen, Markus J\|Karhu, Auli
PMID:	21234763

402.
Journal:	Clin Cancer Res. 2011 Mar 1;17(5):1122-30.
Title:	KRAS mutation is associated with lung metastasis in patients with curatively resected colorectal cancer.
Author:	Tie, Jeanne\|Lipton, Lara\|Desai, Jayesh\|Gibbs, Peter\|Jorissen, Robert N\|Christie, Michael\|Drummond, Katharine J\|Thomson, Benjamin N J\|Usatoff, Valery\|Evans, Peter M\|Pick, Adrian W\|Knight, Simon\|Carne, Peter W G\|Berry, Roger\|Polglase, Adrian\|McMurrick, Paul
PMID:	21239505

403.
Journal:	Anticancer Res. 2011 Jan;31(1):255-61.
Title:	A phase II study of capecitabine, oxaliplatin, bevacizumab and cetuximab in the treatment of metastatic colorectal cancer.
Author:	Wong, Nan Soon\|Fernando, Nishan H\|Nixon, Andrew B\|Cushman, Stephanie\|Aklilu, Mebea\|Bendell, Johanna C\|Morse, Michael A\|Blobe, Gerard C\|Ashton, Jill\|Pang, Herbert\|Hurwitz, Herbert I
PMID:	21273607

404.
Journal:	Pathol Oncol Res. 2011 Sep;17(3):633-7.
Title:	B-Raf mutations, microsatellite instability and p53 protein expression in sporadic basal cell carcinomas.
Author:	Stamatelli, Angeliki\|Saetta, Angelica A\|Bei, Thaleia\|Kavantzas, Nicolaos\|Michalopoulos, Nicolaos V\|Patsouris, Efstratios\|Aroni, Kiriaki
PMID:	21274671

405.
Journal:	PLoS One. 2011 Jan 20;6(1):e15980.
Title:	Impact of KRAS, BRAF, PIK3CA mutations, PTEN, AREG, EREG expression and skin rash in >/= 2 line cetuximab-based therapy of colorectal cancer patients.
Author:	Saridaki, Zacharenia\|Tzardi, Maria\|Papadaki, Chara\|Sfakianaki, Maria\|Pega, Fraga\|Kalikaki, Aristea\|Tsakalaki, Eleftheria\|Trypaki, Maria\|Messaritakis, Ippokratis\|Stathopoulos, Efstathios\|Mavroudis, Dimitris\|Georgoulias, Vassilis\|Souglakos, John
PMID:	21283802

406.
Journal:	Br J Cancer. 2011 Mar 1;104(5):856-62.
Title:	BRAF mutation is a powerful prognostic factor in advanced and recurrent colorectal cancer.
Author:	Yokota, T\|Ura, T\|Shibata, N\|Takahari, D\|Shitara, K\|Nomura, M\|Kondo, C\|Mizota, A\|Utsunomiya, S\|Muro, K\|Yatabe, Y
PMID:	21285991

407.
Journal:	Cancer Genomics Proteomics. 2011 Jan-Feb;8(1):15-8.
Title:	BRAF p.Val600Glu (V600E) somatic mutation is mainly associated with MSS phenotype in metastatic colorectal cancer.
Author:	Qiu, Jinghua\|Compagnone, Marion\|Laibe, Sophy\|Lagarde, Arnaud\|Goncalves, Anthony\|Turrini, Olivier\|Xerri, Luc\|Monges, Genevieve\|Olschwang, Sylviane
PMID:	21289333

408.
Journal:	Genes Chromosomes Cancer. 2011 May;50(5):307-12.
Title:	Frequency of KRAS, BRAF, and NRAS mutations in colorectal cancer.
Author:	Vaughn, Cecily P\|Zobell, Scott D\|Furtado, Larissa V\|Baker, Christine L\|Samowitz, Wade S
PMID:	21305640

409.
Journal:	Clin Cancer Res. 2011 Mar 15;17(6):1452-62.
Title:	STAT3 expression, molecular features, inflammation patterns, and prognosis in a database of 724 colorectal cancers.
Author:	Morikawa, Teppei\|Baba, Yoshifumi\|Yamauchi, Mai\|Kuchiba, Aya\|Nosho, Katsuhiko\|Shima, Kaori\|Tanaka, Noriko\|Huttenhower, Curtis\|Frank, David A\|Fuchs, Charles S\|Ogino, Shuji
PMID:	21310826

410.
Journal:	Hum Pathol. 2011 Jul;42(7):1047-52.
Title:	A novel case of rhabdoid colon carcinoma associated with a positive CpG island methylator phenotype and BRAF mutation.
Author:	Pancione, Massimo\|Di Blasi, Arturo\|Sabatino, Lina\|Fucci, Alessandra\|Dalena, Anna Maria\|Palombi, Natalia\|Carotenuto, Pietro\|Aquino, Gabriella\|Daniele, Bruno\|Normanno, Nicola\|Colantuoni, Vittorio
PMID:	21315413

411.
Journal:	J Gastroenterol Hepatol. 2011 Mar;26(3):599-607.
Title:	Analysis of K-ras, BRAF, and PIK3CA mutations in laterally-spreading tumors of the colorectum.
Author:	Kaji, Eisuke\|Kato, Jun\|Suzuki, Hideyuki\|Akita, Mitsuhiro\|Horii, Joichiro\|Saito, Shunsuke\|Higashi, Reiji\|Ishikawa, Shin\|Kuriyama, Motoaki\|Hiraoka, Sakiko\|Uraoka, Toshio\|Yamamoto, Kazuhide
PMID:	21332555

412.
Journal:	Mod Pathol. 2011 May;24(5):729-38.
Title:	Clinicopathological and molecular characterization of colorectal micropapillary carcinoma.
Author:	Verdu, Montse\|Roman, Ruth\|Calvo, Miquel\|Rodon, Natalia\|Garcia, Beatriz\|Gonzalez, Marta\|Vidal, August\|Puig, Xavier
PMID:	21336262

413.
Journal:	Cancer Chemother Pharmacol. 2011 Oct;68(4):1045-55.
Title:	Analysis of KRAS, BRAF, PTEN, IGF1R, EGFR intron 1 CA status in both primary tumors and paired metastases in determining benefit from cetuximab therapy in colon cancer.
Author:	Park, Jin Hyun\|Han, Sae-Won\|Oh, Do-Youn\|Im, Seock-Ah\|Jeong, Seung-Yong\|Park, Kyu Joo\|Kim, Tae-You\|Bang, Yung-Jue\|Park, Jae-Gahb
PMID:	21340604

414.
Journal:	Discov Med. 2011 Feb;11(57):95-105.
Title:	The role of the epidermal growth factor receptor in the mechanism and treatment of colorectal cancer.
Author:	Yarom, Nirit\|Jonker, Derek J
PMID:	21356164

415.
Journal:	J Clin Oncol. 2011 Apr 1;29(10):1261-70.
Title:	Value of mismatch repair, KRAS, and BRAF mutations in predicting recurrence and benefits from chemotherapy in colorectal cancer.
Author:	Hutchins, Gordon\|Southward, Katie\|Handley, Kelly\|Magill, Laura\|Beaumont, Claire\|Stahlschmidt, Jens\|Richman, Susan\|Chambers, Philip\|Seymour, Matthew\|Kerr, David\|Gray, Richard\|Quirke, Philip
PMID:	21383284

416.
Journal:	World J Gastroenterol. 2011 Feb 14;17(6):809-16.
Title:	Clinical significance of K-ras and BRAF mutations in Chinese colorectal cancer patients.
Author:	Shen, Hong\|Yuan, Ying\|Hu, Han-Guang\|Zhong, Xian\|Ye, Xiao-Xian\|Li, Mo-Dan\|Fang, Wei-Jia\|Zheng, Shu
PMID:	21390154

417.
Journal:	J Natl Cancer Inst. 2011 Apr 20;103(8):674-88.
Title:	Effect of simvastatin on cetuximab resistance in human colorectal cancer with KRAS mutations.
Author:	Lee, Jeeyun\|Lee, Inkyoung\|Han, Boram\|Park, Joon Oh\|Jang, Jiryeon\|Park, Chaehwa\|Kang, Won Ki
PMID:	21398618

418.
Journal:	Mod Pathol. 2011 Jul;24(7):1015-22.
Title:	Up and downregulation of p16(Ink4a) expression in BRAF-mutated polyps/adenomas indicates a senescence barrier in the serrated route to colon cancer.
Author:	Kriegl, Lydia\|Neumann, Jens\|Vieth, Michael\|Greten, Florian R\|Reu, Simone\|Jung, Andreas\|Kirchner, Thomas
PMID:	21423154

419.
Journal:	Oncol Rep. 2011 Jun;25(6):1691-7.
Title:	KRAS, BRAF and PIK3CA mutations in human colorectal cancer: relationship with metastatic colorectal cancer.
Author:	Li, Hong-Tao\|Lu, Yuan-Yuan\|An, Yan-Xin\|Wang, Xin\|Zhao, Qing-Chuan
PMID:	21424126

420.
Journal:	Cancer. 2011 Apr 1;117(7):1399-408.
Title:	Phosphorylated AKT expression is associated with PIK3CA mutation, low stage, and favorable outcome in 717 colorectal cancers.
Author:	Baba, Yoshifumi\|Nosho, Katsuhiko\|Shima, Kaori\|Hayashi, Marika\|Meyerhardt, Jeffrey A\|Chan, Andrew T\|Giovannucci, Edward\|Fuchs, Charles S\|Ogino, Shuji
PMID:	21425139

421.
Journal:	Cancer J. 2011 Mar-Apr;17(2):114-26.
Title:	Molecular predictors of response to chemotherapy in colorectal cancer.
Author:	Dienstmann, Rodrigo\|Vilar, Eduardo\|Tabernero, Josep
PMID:	21427555

422.
Journal:	Pathology. 2011 Apr;43(3):228-33.
Title:	Clinically important molecular features of Peruvian colorectal tumours: high prevalence of DNA mismatch repair deficiency and low incidence of KRAS mutations.
Author:	Egoavil, C M\|Montenegro, P\|Soto, J L\|Casanova, L\|Sanchez-Lihon, J\|Castillejo, M I\|Martinez-Canto, A\|Perez-Carbonell, L\|Castillejo, A\|Guarinos, C\|Barbera, V M\|Jover, R\|Paya, A\|Alenda, C
PMID:	21436632

423.
Journal:	Sci Signal. 2011 Mar 29;4(166):ra17.
Title:	Amplification of the driving oncogene, KRAS or BRAF, underpins acquired resistance to MEK1/2 inhibitors in colorectal cancer cells.
Author:	Little, Annette S\|Balmanno, Kathryn\|Sale, Matthew J\|Newman, Scott\|Dry, Jonathan R\|Hampson, Mark\|Edwards, Paul A W\|Smith, Paul D\|Cook, Simon J
PMID:	21447798

424.
Journal:	Pathol Oncol Res. 2011 Dec;17(4):819-25.
Title:	High frequency of genes' promoter methylation, but lack of BRAF V600E mutation among Iranian colorectal cancer patients.
Author:	Naghibalhossaini, Fakhraddin\|Hosseini, Hamideh Mahmoodzadeh\|Mokarram, Pooneh\|Zamani, Mozhdeh
PMID:	21455633

425.
Journal:	Cancer. 2011 Oct 15;117(20):4623-32.
Title:	Impact of BRAF mutation and microsatellite instability on the pattern of metastatic spread and prognosis in metastatic colorectal cancer.
Author:	Tran, Ben\|Kopetz, Scott\|Tie, Jeanne\|Gibbs, Peter\|Jiang, Zhi-Qin\|Lieu, Christopher H\|Agarwal, Atin\|Maru, Dipen M\|Sieber, Oliver\|Desai, Jayesh
PMID:	21456008

426.
Journal:	Cancer Res. 2011 May 15;71(10):3635-48.
Title:	The dual EGFR/HER2 inhibitor lapatinib synergistically enhances the antitumor activity of the histone deacetylase inhibitor panobinostat in colorectal cancer models.
Author:	LaBonte, Melissa J\|Wilson, Peter M\|Fazzone, Will\|Russell, Jared\|Louie, Stan G\|El-Khoueiry, Anthony\|Lenz, Heinz-Josef\|Ladner, Robert D
PMID:	21464044

427.
Journal:	Anal Cell Pathol (Amst). 2011;34(1-2):61-6.
Title:	Intra-tumoral heterogeneity of KRAS and BRAF mutation status in patients with advanced colorectal cancer (aCRC) and cost-effectiveness of multiple sample testing.
Author:	Richman, Susan D\|Chambers, Philip\|Seymour, Matthew T\|Daly, Catherine\|Grant, Sophie\|Hemmings, Gemma\|Quirke, Philip
PMID:	21483104

428.
Journal:	Cancer. 2011 May 1;117(9):1847-54.
Title:	DNA methylation predicts recurrence from resected stage III proximal colon cancer.
Author:	Ahn, Joong Bae\|Chung, Woon Bok\|Maeda, Osamu\|Shin, Sang Joon\|Kim, Hyun Soo\|Chung, Hyun Chul\|Kim, Nam Kyu\|Issa, Jean-Pierre J
PMID:	21509761

429.
Journal:	Mod Pathol. 2011 Aug;24(8):1090-100.
Title:	Metastatic colorectal cancer KRAS genotyping in routine practice: results and pitfalls.
Author:	Lamy, Aude\|Blanchard, France\|Le Pessot, Florence\|Sesboue, Richard\|Di Fiore, Frederic\|Bossut, Jessie\|Fiant, Elodie\|Frebourg, Thierry\|Sabourin, Jean-Christophe
PMID:	21516079

430.
Journal:	JAMA. 2011 Apr 27;305(16):1685-94.
Title:	Association of CTNNB1 (beta-catenin) alterations, body mass index, and physical activity with survival in patients with colorectal cancer.
Author:	Morikawa, Teppei\|Kuchiba, Aya\|Yamauchi, Mai\|Meyerhardt, Jeffrey A\|Shima, Kaori\|Nosho, Katsuhiko\|Chan, Andrew T\|Giovannucci, Edward\|Fuchs, Charles S\|Ogino, Shuji
PMID:	21521850

431.
Journal:	Arch Pathol Lab Med. 2011 May;135(5):578-87.
Title:	Molecular diagnostics of colorectal cancer.
Author:	Bedeir, Ahmed\|Krasinskas, Alyssa M
PMID:	21526956

432.
Journal:	Int J Colorectal Dis. 2011 Nov;26(11):1387-95.
Title:	Mutations in BRAF correlate with poor survival of colorectal cancers in Chinese population.
Author:	Liou, Jyh-Ming\|Wu, Ming-Shiang\|Shun, Chia-Tung\|Chiu, Han-Mo\|Chen, Mei-Jyh\|Chen, Chien-Chuan\|Wang, Hsiu-Po\|Lin, Jaw-Town\|Liang, Jin-Tung
PMID:	21553007

433.
Journal:	BMC Res Notes. 2011 May 10;4:140.
Title:	Analysis of the anti-tumor effect of cetuximab using protein kinetics and mouse xenograft models.
Author:	Matsuo, Teppei\|Nishizuka, Satoshi S\|Ishida, Kazushige\|Iwaya, Takeshi\|Ikeda, Miyuki\|Wakabayashi, Go
PMID:	21554739

434.
Journal:	Clin Cancer Res. 2011 May 15;17(10):3469-77.
Title:	Biomarkers for cetuximab-based neoadjuvant radiochemotherapy in locally advanced rectal cancer.
Author:	Grimminger, Peter P\|Danenberg, Peter\|Dellas, Kathrin\|Arnold, Dirk\|Rodel, Claus\|Machiels, Jean-Pascal\|Haustermans, Karin\|Debucquoy, Annelies\|Velenik, Vaneja\|Sempoux, Christine\|Bracko, Matej\|Holscher, Arnulf H\|Semrau, Robert\|Yang, Dongyun\|Danenberg, Kathlee
PMID:	21558395

435.
Journal:	Br J Cancer. 2011 Jun 7;104(12):1906-12.
Title:	Promoter methylation of Wnt5a is associated with microsatellite instability and BRAF V600E mutation in two large populations of colorectal cancer patients.
Author:	Rawson, J B\|Mrkonjic, M\|Daftary, D\|Dicks, E\|Buchanan, D D\|Younghusband, H B\|Parfrey, P S\|Young, J P\|Pollett, A\|Green, R C\|Gallinger, S\|McLaughlin, J R\|Knight, J A\|Bapat, B
PMID:	21587258

436.
Journal:	J Dig Dis. 2011 Jun;12(3):193-8.
Title:	Clinical features and molecular alterations of traditional serrated adenoma in sporadic colorectal carcinogenesis.
Author:	Han, Ying\|Zhou, Zhi Yong
PMID:	21615873

437.
Journal:	Inflamm Bowel Dis. 2011 Sep;17(9):1966-70.
Title:	Relative role of methylator and tumor suppressor pathways in ulcerative colitis-associated colon cancer.
Author:	Sanchez, Julian A\|Dejulius, Kathryn L\|Bronner, Mary\|Church, James M\|Kalady, Matthew F
PMID:	21618350

438.
Journal:	Clin Cancer Res. 2011 Jul 15;17(14):4901-14.
Title:	Increased detection sensitivity for KRAS mutations enhances the prediction of anti-EGFR monoclonal antibody resistance in metastatic colorectal cancer.
Author:	Molinari, Francesca\|Felicioni, Lara\|Buscarino, Michela\|De Dosso, Sara\|Buttitta, Fiamma\|Malatesta, Sara\|Movilia, Alessandra\|Luoni, Marco\|Boldorini, Renzo\|Alabiso, Oscar\|Girlando, Salvatore\|Soini, Barbara\|Spitale, Alessandra\|Di Nicolantonio, Federica\|Salett
PMID:	21632860

439.
Journal:	Am J Pathol. 2011 Jun;178(6):2700-7.
Title:	A serrated colorectal cancer pathway predominates over the classic WNT pathway in patients with hyperplastic polyposis syndrome.
Author:	Boparai, Karam S\|Dekker, Evelien\|Polak, Mirjam M\|Musler, Alex R\|van Eeden, Susanne\|van Noesel, Carel J M
PMID:	21641392

440.
Journal:	Lancet. 2011 Jun 18;377(9783):2103-14.
Title:	Addition of cetuximab to oxaliplatin-based first-line combination chemotherapy for treatment of advanced colorectal cancer: results of the randomised phase 3 MRC COIN trial.
Author:	Maughan, Timothy S\|Adams, Richard A\|Smith, Christopher G\|Meade, Angela M\|Seymour, Matthew T\|Wilson, Richard H\|Idziaszczyk, Shelley\|Harris, Rebecca\|Fisher, David\|Kenny, Sarah L\|Kay, Edward\|Mitchell, Jenna K\|Madi, Ayman\|Jasani, Bharat\|James, Michelle D\|Brid
PMID:	21641636

441.
Journal:	J Biomed Sci. 2011 Jun 7;18:36.
Title:	Molecular profile and copy number analysis of sporadic colorectal cancer in Taiwan.
Author:	Lin, Chien-Hsing\|Lin, Jen-Kou\|Chang, Shih-Ching\|Chang, Ya-Hui\|Chang, Hwey-May\|Liu, Jin-Hwang\|Li, Ling-Hui\|Chen, Yuan-Tsong\|Tsai, Shih-Feng\|Chen, Wei-Shone
PMID:	21645411

442.
Journal:	J Clin Oncol. 2011 Jul 1;29(19):2728-9.
Title:	Impact of KRAS and BRAF gene mutations on targeted therapies in colorectal cancer.
Author:	Bass, Adam
PMID:	21646605

443.
Journal:	J Clin Oncol. 2011 Jul 1;29(19):2675-82.
Title:	Impact of KRAS and BRAF Gene Mutation Status on Outcomes From the Phase III AGITG MAX Trial of Capecitabine Alone or in Combination With Bevacizumab and Mitomycin in Advanced Colorectal Cancer.
Author:	Price, Timothy J\|Hardingham, Jennifer E\|Lee, Chee K\|Weickhardt, Andrew\|Townsend, Amanda R\|Wrin, Joseph W\|Chua, Ann\|Shivasami, Aravind\|Cummins, Michelle M\|Murone, Carmel\|Tebbutt, Niall C
PMID:	21646616

444.
Journal:	Patholog Res Int. 2011;2011:157073.
Title:	Serrated polyposis: an enigmatic model of colorectal cancer predisposition.
Author:	Rosty, Christophe\|Parry, Susan\|Young, Joanne P
PMID:	21660283

445.
Journal:	J Pathol. 2011 Nov;225(3):336-43.
Title:	Comprehensive analysis of CpG island methylator phenotype (CIMP)-high, -low, and -negative colorectal cancers based on protein marker expression and molecular features.
Author:	Zlobec, Inti\|Bihl, Michel\|Foerster, Anja\|Rufle, Alex\|Lugli, Alessandro
PMID:	21660972

446.
Journal:	Hum Pathol. 2011 Dec;42(12):1897-910.
Title:	Distinctive patterns of p53 protein expression and microsatellite instability in human colorectal cancer.
Author:	Nyiraneza, Christine\|Jouret-Mourin, Anne\|Kartheuser, Alex\|Camby, Philippe\|Plomteux, Olivier\|Detry, Roger\|Dahan, Karin\|Sempoux, Christine
PMID:	21665242

447.
Journal:	J Surg Oncol. 2011 Nov 1;104(6):661-6.
Title:	The status of EGFR-associated genes could predict the outcome and tumor response of chemo-refractory metastatic colorectal patients using cetuximab and chemotherapy.
Author:	Lin, Jen-Kou\|Lin, An-Jen\|Lin, Chun-Chi\|Lan, Yuan-Tzu\|Yang, Shung-Haur\|Li, Anna Fen-Yau\|Chang, Shih-Ching
PMID:	21671463

448.
Journal:	Br J Cancer. 2011 Jul 12;105(2):281-7.
Title:	Molecular alterations associated with liver metastases development in colorectal cancer patients.
Author:	Bruin, S C\|He, Y\|Mikolajewska-Hanclich, I\|Liefers, G-J\|Klijn, C\|Vincent, A\|Verwaal, V J\|de Groot, K A\|Morreau, H\|van Velthuysen, M-L F\|Tollenaar, R A E M\|van 't Veer, L J
PMID:	21673680

449.
Journal:	Sci Signal. 2011;4(170):er2.
Title:	A correction to the research article titled: "Amplification of the driving oncogene, KRAS or BRAF, underpins acquired resistance to MEK1/2 inhibitors in colorectal cancer cells" by A. S. Little, K. Balmanno, M. J. Sale, S. Newman, J. R. Dry, M. Hampson, P
Author:	Little, Annette S\|Balmanno, Kathryn\|Sale, Matthew J\|Newman, Scott\|Dry, Jonathan R\|Hampson, Mark\|Edwards, Paul A W\|Smith, Paul D\|Cook, Simon J
PMID:	21674991

450.
Journal:	Drugs R D. 2011;11(2):101-11.
Title:	Use of bevacizumab in metastatic colorectal cancer: report from the Mexican opinion and analysis forum on colorectal cancer treatment with bevacizumab (September 2009).
Author:	Zinser-Sierra, Juan W\|Rodriguez-Ramirez, Saul\|Villalobos-Valencia, Ricardo\|Ramirez-Marquez, Marcelino
PMID:	21679003

451.
Journal:	PLoS One. 2011;6(6):e20919.
Title:	Cten is targeted by Kras signalling to regulate cell motility in the colon and pancreas.
Author:	Al-Ghamdi, Saleh\|Albasri, Abdulkader\|Cachat, Julien\|Ibrahem, Salih\|Muhammad, Belal A\|Jackson, Darryl\|Nateri, Abdolrahman S\|Kindle, Karin B\|Ilyas, Mohammad
PMID:	21698197

452.
Journal:	J Mol Diagn. 2011 Jul;13(4):436-45.
Title:	KRAS, NRAS, PIK3CA exon 20, and BRAF genotypes in synchronous and metachronous primary colorectal cancers diagnostic and therapeutic implications.
Author:	Balschun, Katharina\|Haag, Jochen\|Wenke, Ann-Kathrin\|von Schonfels, Witigo\|Schwarz, Nicolas T\|Rocken, Christoph
PMID:	21704278

453.
Journal:	J Mol Diagn. 2011 Sep;13(5):467-73.
Title:	Comparison of allelic discrimination by dHPLC, HRM, and TaqMan in the detection of BRAF mutation V600E.
Author:	Carbonell, Pablo\|Turpin, Maria C\|Torres-Moreno, Daniel\|Molina-Martinez, Irene\|Garcia-Solano, Jose\|Perez-Guillermo, Miguel\|Conesa-Zamora, Pablo
PMID:	21708284

454.
Journal:	Br J Cancer. 2011 Jul 12;105(2):246-54.
Title:	Pyrosequencing-based methods reveal marked inter-individual differences in oncogene mutation burden in human colorectal tumours.
Author:	Weidlich, S\|Walsh, K\|Crowther, D\|Burczynski, M E\|Feuerstein, G\|Carey, F A\|Steele, R J C\|Wolf, C R\|Miele, G\|Smith, G
PMID:	21712828

455.
Journal:	Clin Colorectal Cancer. 2011 Dec;10(4):325-32.
Title:	Is there a role for IGF1R and c-MET pathways in resistance to cetuximab in metastatic colorectal cancer?
Author:	Inno, Alessandro\|Di Salvatore, Mariantonietta\|Cenci, Tonia\|Martini, Maurizio\|Orlandi, Armando\|Strippoli, Antonia\|Ferrara, Anna Maria\|Bagala, Cinzia\|Cassano, Alessandra\|Larocca, Luigi Maria\|Barone, Carlo
PMID:	21729677

456.
Journal:	Clin Colorectal Cancer. 2011 Dec;10(4):279-89.
Title:	Development of molecular biomarkers in individualized treatment of colorectal cancer.
Author:	De Mattos-Arruda, Leticia\|Dienstmann, Rodrigo\|Tabernero, Josep
PMID:	21729679

457.
Journal:	PLoS One. 2011;6(6):e21102.
Title:	B vitamins, methionine and alcohol intake and risk of colon cancer in relation to BRAF mutation and CpG island methylator phenotype (CIMP).
Author:	Schernhammer, Eva S\|Giovannucci, Edward\|Baba, Yoshifumi\|Fuchs, Charles S\|Ogino, Shuji
PMID:	21738611

458.
Journal:	PLoS One. 2011;6(6):e21632.
Title:	Selective BRAFV600E inhibitor PLX4720, requires TRAIL assistance to overcome oncogenic PIK3CA resistance.
Author:	Oikonomou, Eftychia\|Koc, Michal\|Sourkova, Vladimira\|Andera, Ladislav\|Pintzas, Alexander
PMID:	21738740

459.
Journal:	Oncologist. 2011;16(9):1239-49.
Title:	Concordance of predictive markers for EGFR inhibitors in primary tumors and metastases in colorectal cancer: a review.
Author:	Baas, Jara M\|Krens, Lisanne L\|Guchelaar, Henk-Jan\|Morreau, Hans\|Gelderblom, Hans
PMID:	21742964

460.
Journal:	Mod Pathol. 2011 Oct;24(10):1404-12.
Title:	VEGFA gene locus (6p12) amplification identifies a small but highly aggressive subgroup of colorectal cancer [corrected] patients.
Author:	Vlajnic, Tatjana\|Andreozzi, Maria Carla\|Schneider, Sandra\|Tornillo, Luigi\|Karamitopoulou, Eva\|Lugli, Alessandro\|Ruiz, Christian\|Zlobec, Inti\|Terracciano, Luigi
PMID:	21743435

461.
Journal:	Ann Intern Med. 2011 Jul 19;155(2):69-79.
Title:	Strategies to identify the Lynch syndrome among patients with colorectal cancer: a cost-effectiveness analysis.
Author:	Ladabaum, Uri\|Wang, Grace\|Terdiman, Jonathan\|Blanco, Amie\|Kuppermann, Miriam\|Boland, C Richard\|Ford, James\|Elkin, Elena\|Phillips, Kathryn A
PMID:	21768580

462.
Journal:	Gan To Kagaku Ryoho. 2011 Jul;38(7):1079-83.
Title:	[Predictive biomarkers of anti-EGFR monoclonal anti-body in colorectal cancer].
Author:	Soeda, Hiroshi\|Shimodaira, Hideki\|Ishioka, Chikashi
PMID:	21772090

463.
Journal:	J Clin Oncol. 2011 Sep 1;29(25):3374-80.
Title:	Validation microsatellite path score in a population-based cohort of patients with colorectal cancer.
Author:	Bessa, Xavier\|Alenda, Cristina\|Paya, Artemio\|Alvarez, Cristina\|Iglesias, Mar\|Seoane, Agustin\|Dedeu, Josep Maria\|Abuli, Anna\|Ilzarbe, Lucas\|Navarro, Gemma\|Pellise, Maria\|Balaguer, Francesc\|Castellvi-Bel, Sergi\|Llor, Xavier\|Castells, Antoni\|Jover, Rodrigo\|A
PMID:	21788563

464.
Journal:	Semin Oncol. 2011 Aug;38(4):576-87.
Title:	Predictive molecular classifiers in colorectal cancer.
Author:	Bohanes, Pierre\|LaBonte, Melissa J\|Winder, Thomas\|Lenz, Heinz-Josef
PMID:	21810517

465.
Journal:	Rinsho Byori. 2011 Jun;59(6):598-601.
Title:	[KRAS mutation test].
Author:	Hinoda, Yuji
PMID:	21815483

466.
Journal:	Nat Rev Clin Oncol. 2011 Aug 9;8(12):711-9.
Title:	Cancer immunology--analysis of host and tumor factors for personalized medicine.
Author:	Ogino, Shuji\|Galon, Jerome\|Fuchs, Charles S\|Dranoff, Glenn
PMID:	21826083

467.
Journal:	BMC Cancer. 2011 Aug 10;11:344.
Title:	The CpG island methylator phenotype may confer a survival benefit in patients with stage II or III colorectal carcinomas receiving fluoropyrimidine-based adjuvant chemotherapy.
Author:	Min, Byung-Hoon\|Bae, Jeong Mo\|Lee, Eui Jin\|Yu, Hong Suk\|Kim, Young-Ho\|Chang, Dong Kyung\|Kim, Hee Cheol\|Park, Cheol Keun\|Lee, Suk-Hee\|Kim, Kyoung-Mee\|Kang, Gyeong Hoon
PMID:	21827707

468.
Journal:	PLoS One. 2011;6(7):e22769.
Title:	PIK3CA mutations frequently coexist with RAS and BRAF mutations in patients with advanced cancers.
Author:	Janku, Filip\|Lee, J Jack\|Tsimberidou, Apostolia M\|Hong, David S\|Naing, Aung\|Falchook, Gerald S\|Fu, Siqing\|Luthra, Rajyalakshmi\|Garrido-Laguna, Ignacio\|Kurzrock, Razelle
PMID:	21829508

469.
Journal:	Am J Manag Care. 2011 Aug 1;17(8):e288-300.
Title:	Lynch syndrome screening implementation: business analysis by a healthcare system.
Author:	Gudgeon, James M\|Williams, Janet L\|Burt, Randall W\|Samowitz, Wade S\|Snow, Gregory L\|Williams, Marc S
PMID:	21851136

470.
Journal:	Endocr Relat Cancer. 2011 Oct 27;18(6):C31-4.
Title:	Quantitative validation of GJC1 promoter hypermethylation in benign and malignant colorectal tumors.
Author:	Ahmed, Deeqa\|Lothe, Ragnhild A\|Rivedal, Edgar\|Lind, Guro E
PMID:	21868474

471.
Journal:	Sci Transl Med. 2011 Sep 7;3(99):99ra86.
Title:	Activation of ERBB2 signaling causes resistance to the EGFR-directed therapeutic antibody cetuximab.
Author:	Yonesaka, Kimio\|Zejnullahu, Kreshnik\|Okamoto, Isamu\|Satoh, Taroh\|Cappuzzo, Federico\|Souglakos, John\|Ercan, Dalia\|Rogers, Andrew\|Roncalli, Massimo\|Takeda, Masayuki\|Fujisaka, Yasuhito\|Philips, Juliet\|Shimizu, Toshio\|Maenishi, Osamu\|Cho, Yonggon\|Sun, Jason\|D
PMID:	21900593

472.
Journal:	Cancer Prev Res (Phila). 2011 Dec;4(12):2035-43.
Title:	Alcohol intake and colorectal cancer risk by molecularly defined subtypes in a prospective study of older women.
Author:	Razzak, Anthony A\|Oxentenko, Amy S\|Vierkant, Robert A\|Tillmans, Lori S\|Wang, Alice H\|Weisenberger, Daniel J\|Laird, Peter W\|Lynch, Charles F\|Anderson, Kristin E\|French, Amy J\|Haile, Robert W\|Harnack, Lisa J\|Slager, Susan L\|Smyrk, Thomas C\|Thibodeau, Stephe
PMID:	21900595

473.
Journal:	PLoS One. 2011;6(8):e24114.
Title:	Molecular genetic analysis of 103 sporadic colorectal tumours in Czech patients.
Author:	Vasovcak, Peter\|Pavlikova, Kristyna\|Sedlacek, Zdenek\|Skapa, Petr\|Kouda, Martin\|Hoch, Jiri\|Krepelova, Anna
PMID:	21901162

474.
Journal:	Radiat Oncol. 2011 Sep 12;6:114.
Title:	Phospho-ERK and AKT status, but not KRAS mutation status, are associated with outcomes in rectal cancer treated with chemoradiotherapy.
Author:	Davies, Janine M\|Trembath, Dimitri\|Deal, Allison M\|Funkhouser, William K\|Calvo, Benjamin F\|Finnegan, Timothy\|Weck, Karen E\|Tepper, Joel E\|O'Neil, Bert H
PMID:	21910869

475.
Journal:	Cancer Biol Ther. 2011 Oct 1;12(7):557-68. Epub 2011 Oct 1.
Title:	Preliminary observations indicate variable patterns of plasma 5-fluorouracil (5-FU) levels during dose optimization of infusional 5-FU in colorectal cancer patients.
Author:	Kline, Christina Leah\|Sheikh, Hassan S\|Scicchitano, Angelique\|Gingrich, Rebecca\|Beachler, Cheryl\|Finnberg, Niklas K\|Liao, Jason\|Sivik, Jeffrey\|El-Deiry, Wafik S
PMID:	21931273

476.
Journal:	Rinsho Byori. 2011 Aug;59(8):757-62.
Title:	[Tm analysis method using a quenching probe is a simple and rapid way to simultaneously detect KRAS and BRAF mutations].
Author:	Akagi, Kiwamu\|Arai, Yoshiko
PMID:	21942085

477.
Journal:	Mol Cancer. 2011 Sep 23;10:118.
Title:	BRAF and RAS oncogenes regulate Rho GTPase pathways to mediate migration and invasion properties in human colon cancer cells: a comparative study.
Author:	Makrodouli, Eleni\|Oikonomou, Eftychia\|Koc, Michal\|Andera, Ladislav\|Sasazuki, Takehiko\|Shirasawa, Senji\|Pintzas, Alexander
PMID:	21943101

478.
Journal:	BMC Cancer. 2011 Sep 24;11:406.
Title:	Clinical pharmacogenomic testing of KRAS, BRAF and EGFR mutations by high resolution melting analysis and ultra-deep pyrosequencing.
Author:	Borras, Emma\|Jurado, Ismael\|Hernan, Imma\|Gamundi, Maria Jose\|Dias, Miguel\|Marti, Isabel\|Mane, Begona\|Arcusa, Angels\|Agundez, Jose A G\|Blanca, Miguel\|Carballo, Miguel
PMID:	21943394

479.
Journal:	Arch Med Res. 2011 Aug;42(6):457-62.
Title:	Analysis of DNA mismatch repair proteins expression and BRAF V600E mutation in a subset of early- and late-onset colorectal carcinoma patients in Mexico.
Author:	Luevano-Gonzalez, Arturo\|Guzman, Arturo Quintanilla\|Ancer Rodriguez, Jesus\|Ortiz Lopez, Rocio\|Rojas Martinez, Augusto\|Gonzalez Guerrero, Juan Francisco\|Flores Gutierrez, Juan Pablo
PMID:	21945875

480.
Journal:	PLoS One. 2011;6(9):e25062.
Title:	TGFBR2 and BAX mononucleotide tract mutations, microsatellite instability, and prognosis in 1072 colorectal cancers.
Author:	Shima, Kaori\|Morikawa, Teppei\|Yamauchi, Mai\|Kuchiba, Aya\|Imamura, Yu\|Liao, Xiaoyun\|Meyerhardt, Jeffrey A\|Fuchs, Charles S\|Ogino, Shuji
PMID:	21949851

481.
Journal:	Arch Pathol Lab Med. 2011 Oct;135(10):1269-77.
Title:	Microsatellite instability and colorectal cancer.
Author:	Geiersbach, Katherine B\|Samowitz, Wade S
PMID:	21970482

482.
Journal:	Expert Rev Anticancer Ther. 2011 Oct;11(10):1499-503.
Title:	Anti-EGFR therapy in first-line colorectal cancer.
Author:	Lamas, Maria J\|Duran, Goretti\|Gallardo, Elena
PMID:	21999123

483.
Journal:	Expert Rev Mol Diagn. 2011 Nov;11(8):799-802.
Title:	Detection of KRAS and BRAF mutations in advanced colorectal cancer by allele-specific single-base primer extension.
Author:	Balschun, Katharina\|Wenke, Ann-Kathrin\|Rocken, Christoph\|Haag, Jochen
PMID:	22022941

484.
Journal:	PLoS One. 2011;6(10):e25806.
Title:	BRAF mutations in advanced cancers: clinical characteristics and outcomes.
Author:	El-Osta, Hazem\|Falchook, Gerald\|Tsimberidou, Apostolia\|Hong, David\|Naing, Aung\|Kim, Kevin\|Wen, Sijin\|Janku, Filip\|Kurzrock, Razelle
PMID:	22039425

485.
Journal:	J Natl Compr Canc Netw. 2011 Nov;9(11):1293-302.
Title:	Biomarker use in colorectal cancer therapy.
Author:	Kelley, Robin K\|Wang, Grace\|Venook, Alan P
PMID:	22056657

486.
Journal:	Pathol Res Pract. 2011 Dec 15;207(12):762-8.
Title:	Frequency of KRAS, BRAF, and PIK3CA mutations in advanced colorectal cancers: Comparison of peptide nucleic acid-mediated PCR clamping and direct sequencing in formalin-fixed, paraffin-embedded tissue.
Author:	Kwon, Mi Jung\|Lee, Seung Eun\|Kang, So Young\|Choi, Yoon-La
PMID:	22070922

487.
Journal:	Int J Biol Markers. 2011 Oct-Dec;26(4):276-7.
Title:	KRAS and BRAF mutation status in patients with sporadic colorectal cancer: data from two different Mediterranean countries.
Author:	Symvoulakis, Emmanouil K\|Zaravinos, Apostolos\|Zoras, Odysseas\|Spandidos, Demetrios A
PMID:	22139644

488.
Journal:	Cesk Patol. 2011 Oct;47(4):154-8.
Title:	[Molecular predictive markers of EGFR-targeted therapy in metastatic colorectal cancer].
Author:	Fabian, P\|Berkovcova, J
PMID:	22145213

489.
Journal:	PLoS One. 2011;6(12):e28841.
Title:	Antitumor activity of sorafenib in human cancer cell lines with acquired resistance to EGFR and VEGFR tyrosine kinase inhibitors.
Author:	Morgillo, Floriana\|Martinelli, Erika\|Troiani, Teresa\|Orditura, Michele\|De Vita, Ferdinando\|Ciardiello, Fortunato
PMID:	22174910

490.
Journal:	World J Gastroenterol. 2011 Nov 14;17(42):4729-33.
Title:	Neuroendocrine and squamous colonic composite carcinoma: case report with molecular analysis.
Author:	Wentz, Sabrina C\|Vnencak-Jones, Cindy\|Chopp, William V
PMID:	22180717

491.
Journal:	Oncology. 2011;81 Suppl 1:18-23.
Title:	Signaling pathways in hepatocellular carcinoma.
Author:	Sia, Daniela\|Villanueva, Augusto
PMID:	22212931

492.
Journal:	Folia Histochem Cytobiol. 2011;49(4):570-8.
Title:	Digital pathology in personalized cancer therapy.
Author:	Slodkowska, Janina\|Rojo, Marcial Garcia
PMID:	22252751

493.
Journal:	Cancer Discov. 2011 Nov;1(6):508-23.
Title:	A molecularly annotated platform of patient-derived xenografts ("xenopatients") identifies HER2 as an effective therapeutic target in cetuximab-resistant colorectal cancer.
Author:	Bertotti, Andrea\|Migliardi, Giorgia\|Galimi, Francesco\|Sassi, Francesco\|Torti, Davide\|Isella, Claudio\|Cora, Davide\|Di Nicolantonio, Federica\|Buscarino, Michela\|Petti, Consalvo\|Ribero, Dario\|Russolillo, Nadia\|Muratore, Andrea\|Massucco, Paolo\|Pisacane, Alber
PMID:	22586653

494.
Journal:	Exp Ther Med. 2011 Jul;2(4):695-700.
Title:	Sessile serrated adenoma shares similar genetic and epigenetic features with microsatellite unstable colon cancer in a location-dependent manner.
Author:	Maeda, Takafumi\|Suzuki, Koichi\|Togashi, Kazutomo\|Nokubi, Mitsuhiro\|Saito, Masaaki\|Tsujinaka, Shingo\|Kamiyama, Hidenori\|Konishi, Fumio
PMID:	22977561

495.
Journal:	Chin J Cancer Res. 2011 Dec;23(4):271-5.
Title:	Wild-Type KRAS and BRAF Could Predict Response to Cetuximab in Chinese Colorectal Cancer Patients.
Author:	Gao, Jing\|Wang, Ting-Ting\|Yu, Jing-Wei\|Li, Yan-Yan\|Shen, Lin
PMID:	23357879

496.
Journal:	Cancers (Basel). 2011 Mar 29;3(2):1622-38.
Title:	Predictive and prognostic factors in colorectal cancer: a personalized approach.
Author:	Kulendran, Myutan\|Stebbing, John F\|Marks, Christopher G\|Rockall, Timothy A
PMID:	24212777

497.
Journal:	Cancers (Basel). 2011 Jun 23;3(2):2767-810.
Title:	Review of histopathological and molecular prognostic features in colorectal cancer.
Author:	Marzouk, Ola\|Schofield, John
PMID:	24212832

498.
Journal:	Colorectal Dis. 2012 Jan;14(1):3-17.
Title:	Review of biomarkers in colorectal cancer.
Author:	Newton, K F\|Newman, W\|Hill, J
PMID:	21040359

499.
Journal:	Int J Cancer. 2012 Feb 15;130(4):837-46.
Title:	Increased frequency of 20q gain and copy-neutral loss of heterozygosity in mismatch repair proficient familial colorectal carcinomas.
Author:	Middeldorp, A\|van Eijk, R\|Oosting, J\|Forte, G I\|van Puijenbroek, M\|van Nieuwenhuizen, M\|Corver, W E\|Ruano, D\|Caldes, T\|Wijnen, J\|Morreau, H\|van Wezel, T
PMID:	21445971

500.
Journal:	Int J Cancer. 2012 Mar 1;130(5):1082-92.
Title:	A distinct DNA methylation profile associated with microsatellite and chromosomal stable sporadic colorectal cancers.
Author:	Silver, Andrew\|Sengupta, Neel\|Propper, David\|Wilson, Peter\|Hagemann, Thorsten\|Patel, Asif\|Parker, Alexandra\|Ghosh, Anil\|Feakins, Roger\|Dorudi, Sina\|Suraweera, Nirosha
PMID:	21455990

501.
Journal:	Int J Cancer. 2012 Mar 15;130(6):1367-77.
Title:	Evaluation of predictive models in daily practice for the identification of patients with Lynch syndrome.
Author:	Tresallet, Christophe\|Brouquet, Antoine\|Julie, Catherine\|Beauchet, Alain\|Vallot, Celine\|Menegaux, Fabrice\|Mitry, Emmanuel\|Radvanyi, Francois\|Malafosse, Robert\|Rougier, Philippe\|Nordlinger, Bernard\|Laurent-Puig, Pierre\|Boileau, Catherine\|Emile, Jean-Franco
PMID:	21520036

502.
Journal:	Int J Cancer. 2012 Apr 1;130(7):1567-76.
Title:	p53 mutation is common in microsatellite stable, BRAF mutant colorectal cancers.
Author:	Bond, Catherine E\|Umapathy, Aarti\|Ramsnes, Ingunn\|Greco, Sonia A\|Zhen Zhao, Zhen\|Mallitt, Kylie-Ann\|Buttenshaw, Ron L\|Montgomery, Grant W\|Leggett, Barbara A\|Whitehall, Vicki L J
PMID:	21557216

503.
Journal:	Genome Res. 2012 Feb;22(2):271-82.
Title:	Genome-scale analysis of aberrant DNA methylation in colorectal cancer.
Author:	Hinoue, Toshinori\|Weisenberger, Daniel J\|Lange, Christopher P E\|Shen, Hui\|Byun, Hyang-Min\|Van Den Berg, David\|Malik, Simeen\|Pan, Fei\|Noushmehr, Houtan\|van Dijk, Cornelis M\|Tollenaar, Rob A E M\|Laird, Peter W
PMID:	21659424

504.
Journal:	Mol Biol Rep. 2012 Mar;39(3):2553-60.
Title:	Association between methylation in mismatch repair genes, V600E BRAF mutation and microsatellite instability in colorectal cancer patients.
Author:	Rasuck, Carla G\|Leite, Sinara M O\|Komatsuzaki, Flavia\|Ferreira, Alessandro C S\|Oliveira, Vanessa C\|Gomes, Karina B
PMID:	21681432

505.
Journal:	Int J Surg Pathol. 2012 Apr;20(2):185-90.
Title:	Rhabdoid carcinoma of the colon: a distinct entity with a very aggressive behavior: a case report associated with a polyposis coli and review of the literature.
Author:	Remo, Andrea\|Zanella, Caterina\|Molinari, Enrico\|Talamini, Alberto\|Tollini, Filippo\|Piacentini, Paolo\|Battaglia, Paolo\|Baritono, Elisabetta\|Bonetti, Andrea\|Lanza, Franco\|Fasolin, Antonio\|Manfrin, Erminia\|Vendraminelli, Roberto
PMID:	21791485

506.
Journal:	Clin Colorectal Cancer. 2012 Mar;11(1):53-9.
Title:	Phase II study of irinotecan and cetuximab given every 2 weeks as second-line therapy for advanced colorectal cancer.
Author:	Carneiro, Benedito A\|Ramanathan, Ramesh K\|Fakih, Marwan G\|Krishnamurthi, Smitha S\|Lembersky, Barry C\|Stoller, Ronald G\|Lancaster, Stewart L\|Pinkerton, Richard A\|Crandall, Theodore L\|Schmotzer, Amy R\|Potter, Douglas M\|Bahary, Nathan
PMID:	21813336

507.
Journal:	Int J Oncol. 2012 Jan;40(1):176-84.
Title:	The effect of a dimeric Affibody molecule (ZEGFR:1907)2 targeting EGFR in combination with radiation in colon cancer cell lines.
Author:	Haggblad Sahlberg, Sara\|Spiegelberg, Diana\|Lennartsson, Johan\|Nygren, Peter\|Glimelius, Bengt\|Stenerlow, Bo
PMID:	21879255

508.
Journal:	Int J Cancer. 2012 Aug 15;131(4):813-20.
Title:	Oncogenic PIK3CA mutations in colorectal cancers and polyps.
Author:	Whitehall, Vicki L J\|Rickman, Celestine\|Bond, Catherine E\|Ramsnes, Ingunn\|Greco, Sonia A\|Umapathy, Aarti\|McKeone, Diane\|Faleiro, Rebecca J\|Buttenshaw, Ron L\|Worthley, Daniel L\|Nayler, Sam\|Zhao, Zhen Zhen\|Montgomery, Grant W\|Mallitt, Kylie-Ann\|Jass, Jeremy
PMID:	21932420

509.
Journal:	Surgery. 2012 Apr;151(4):564-70.
Title:	CpG island methylator phenotype infers a poor disease-free survival in locally advanced rectal cancer.
Author:	Jo, Peter\|Jung, Klaus\|Grade, Marian\|Conradi, Lena-Christin\|Wolff, Hendrik A\|Kitz, Julia\|Becker, Heinz\|Ruschoff, Josef\|Hartmann, Arndt\|Beissbarth, Tim\|Muller-Dornieden, Annegret\|Ghadimi, Michael\|Schneider-Stock, Regine\|Gaedcke, Jochen
PMID:	22001634

510.
Journal:	Mol Carcinog. 2012 Dec;51(12):1003-8.
Title:	Assessment of three epigenotypes in colorectal cancer by combined bisulfite restriction analysis.
Author:	Karpinski, Pawel\|Szmida, Elzbieta\|Misiak, Blazej\|Ramsey, David\|Leszczynski, Przemyslaw\|Bebenek, Marek\|Sedziak, Tomasz\|Grzebieniak, Zygmunt\|Jonkisz, Anna\|Lebioda, Arleta\|Sasiadek, Maria M
PMID:	22006538

511.
Journal:	Acta Neuropathol. 2012 Feb;123(2):223-33.
Title:	Immunohistochemical testing of BRAF V600E status in 1,120 tumor tissue samples of patients with brain metastases.
Author:	Capper, David\|Berghoff, Anna Sophie\|Magerle, Manuel\|Ilhan, Aysegul\|Wohrer, Adelheid\|Hackl, Monika\|Pichler, Josef\|Pusch, Stefan\|Meyer, Jochen\|Habel, Antje\|Petzelbauer, Peter\|Birner, Peter\|von Deimling, Andreas\|Preusser, Matthias
PMID:	22012135

512.
Journal:	Gut. 2012 Sep;61(9):1299-305.
Title:	Postmenopausal hormone therapy and colorectal cancer risk by molecularly defined subtypes among older women.
Author:	Limsui, David\|Vierkant, Robert A\|Tillmans, Lori S\|Wang, Alice H\|Weisenberger, Daniel J\|Laird, Peter W\|Lynch, Charles F\|Anderson, Kristin E\|French, Amy J\|Haile, Robert W\|Harnack, Lisa J\|Potter, John D\|Slager, Susan L\|Smyrk, Thomas C\|Thibodeau, Stephen N\|Ce
PMID:	22027477

513.
Journal:	Int J Cancer. 2012 Sep 1;131(5):1169-78.
Title:	Tumor TP53 expression status, body mass index and prognosis in colorectal cancer.
Author:	Morikawa, Teppei\|Kuchiba, Aya\|Liao, Xiaoyun\|Imamura, Yu\|Yamauchi, Mai\|Qian, Zhi Rong\|Nishihara, Reiko\|Sato, Kaori\|Meyerhardt, Jeffrey A\|Fuchs, Charles S\|Ogino, Shuji
PMID:	22038927

514.
Journal:	Anticancer Agents Med Chem. 2012 Feb;12(2):163-71.
Title:	Are KRAS/BRAF mutations potent prognostic and/or predictive biomarkers in colorectal cancers?
Author:	Yokota, Tomoya
PMID:	22043994

515.
Journal:	Clin Cancer Res. 2012 Jan 15;18(2):350-9.
Title:	Molecular analysis of colorectal tumors within a diverse patient cohort at a single institution.
Author:	Sylvester, Brooke E\|Huo, Dezheng\|Khramtsov, Andrey\|Zhang, Jing\|Smalling, Rana V\|Olugbile, Sope\|Polite, Blase N\|Olopade, Olufunmilayo I
PMID:	22114137

516.
Journal:	Am J Pathol. 2012 Feb;180(2):616-25.
Title:	Intermediate methylation epigenotype and its correlation to KRAS mutation in conventional colorectal adenoma.
Author:	Yagi, Koichi\|Takahashi, Hirokazu\|Akagi, Kiwamu\|Matsusaka, Keisuke\|Seto, Yasuyuki\|Aburatani, Hiroyuki\|Nakajima, Atsushi\|Kaneda, Atsushi
PMID:	22115708

517.
Journal:	Fam Cancer. 2012 Mar;11(1):1-6.
Title:	A state-wide population-based program for detection of lynch syndrome based upon immunohistochemical and molecular testing of colorectal tumours.
Author:	Schofield, Lyn\|Grieu, Fabienne\|Goldblatt, Jack\|Amanuel, Benhur\|Iacopetta, Barry
PMID:	22120844

518.
Journal:	Clin Cancer Res. 2012 Feb 1;18(3):890-900.
Title:	Predictive and prognostic roles of BRAF mutation in stage III colon cancer: results from intergroup trial CALGB 89803.
Author:	Ogino, Shuji\|Shima, Kaori\|Meyerhardt, Jeffrey A\|McCleary, Nadine J\|Ng, Kimmie\|Hollis, Donna\|Saltz, Leonard B\|Mayer, Robert J\|Schaefer, Paul\|Whittom, Renaud\|Hantel, Alexander\|Benson, Al B 3rd\|Spiegelman, Donna\|Goldberg, Richard M\|Bertagnolli, Monica M\|Fuch
PMID:	22147942

519.
Journal:	Mol Biol Rep. 2012 May;39(5):5387-91.
Title:	No evidence for PML-RARa bcr1 fusion gene in colorectal cancer.
Author:	Herreros-Villanueva, Marta
PMID:	22167334

520.
Journal:	Clin Cancer Res. 2012 Feb 1;18(3):688-99.
Title:	Primary colorectal cancers and their subsequent hepatic metastases are genetically different: implications for selection of patients for targeted treatment.
Author:	Vermaat, Joost S\|Nijman, Isaac J\|Koudijs, Marco J\|Gerritse, Frank L\|Scherer, Stefan J\|Mokry, Michal\|Roessingh, Wijnand M\|Lansu, Nico\|de Bruijn, Ewart\|van Hillegersberg, Richard\|van Diest, Paul J\|Cuppen, Edwin\|Voest, Emile E
PMID:	22173549

521.
Journal:	Dig Dis Sci. 2012 May;57(5):1261-70.
Title:	Externalization of saw-tooth architecture in small serrated polyps implies the presence of methylation of IGFBP7.
Author:	Kaji, Eisuke\|Uraoka, Toshio\|Kato, Jun\|Hiraoka, Sakiko\|Suzuki, Hideyuki\|Akita, Mitsuhiro\|Saito, Shunsuke\|Tanaka, Takehiro\|Ohara, Nobuya\|Yamamoto, Kazuhide
PMID:	22173745

522.
Journal:	Cancer Res. 2012 Feb 1;72(3):779-89.
Title:	Antitumor activity of BRAF inhibitor vemurafenib in preclinical models of BRAF-mutant colorectal cancer.
Author:	Yang, Hong\|Higgins, Brian\|Kolinsky, Kenneth\|Packman, Kathryn\|Bradley, William D\|Lee, Richard J\|Schostack, Kathleen\|Simcox, Mary Ellen\|Kopetz, Scott\|Heimbrook, David\|Lestini, Brian\|Bollag, Gideon\|Su, Fei
PMID:	22180495

523.
Journal:	Ann Surg Oncol. 2012 Jun;19(6):1944-53.
Title:	Prognostic significance and molecular associations of tumor growth pattern in colorectal cancer.
Author:	Morikawa, Teppei\|Kuchiba, Aya\|Qian, Zhi Rong\|Mino-Kenudson, Mari\|Hornick, Jason L\|Yamauchi, Mai\|Imamura, Yu\|Liao, Xiaoyun\|Nishihara, Reiko\|Meyerhardt, Jeffrey A\|Fuchs, Charles S\|Ogino, Shuji
PMID:	22189472

524.
Journal:	J Mol Histol. 2012 Apr;43(2):137-43.
Title:	High-frequency microsatellite instability and BRAF mutation (V600E) in unselected Serbian patients with colorectal cancer.
Author:	Markovic, Srdjan\|Antic, Jadranka\|Dragicevic, Neda\|Hamelin, Richard\|Krivokapic, Zoran
PMID:	22210186

525.
Journal:	Dis Colon Rectum. 2012 Feb;55(2):128-33.
Title:	BRAF mutations in colorectal cancer are associated with distinct clinical characteristics and worse prognosis.
Author:	Kalady, Matthew F\|Dejulius, Kathryn L\|Sanchez, Julian A\|Jarrar, Awad\|Liu, Xiuli\|Manilich, Elena\|Skacel, Marek\|Church, James M
PMID:	22228154

526.
Journal:	Dis Colon Rectum. 2012 Feb;55(2):181-90.
Title:	Clinicopathologic and molecular characteristics of synchronous colorectal cancers: heterogeneity of clinical outcome depending on microsatellite instability status of individual tumors.
Author:	Bae, Jeong M\|Cho, Nam-Yun\|Kim, Tae-You\|Kang, Gyeong H
PMID:	22228162

527.
Journal:	Clin Cancer Res. 2012 Feb 15;18(4):1177-85.
Title:	Quantitative cell-free DNA, KRAS, and BRAF mutations in plasma from patients with metastatic colorectal cancer during treatment with cetuximab and irinotecan.
Author:	Spindler, Karen-Lise Garm\|Pallisgaard, Niels\|Vogelius, Ivan\|Jakobsen, Anders
PMID:	22228631

528.
Journal:	Curr Cancer Drug Targets. 2012 Feb;12(2):124-31.
Title:	Analysis of the concordance in the EGFR pathway status between primary tumors and related metastases of colorectal cancer patients:implications for cancer therapy.
Author:	Cejas, P\|Lopez-Gomez, M\|Aguayo, C\|Madero, R\|Moreno-Rubio, J\|de Castro Carpeno, J\|Belda-Iniesta, C\|Barriuso, J\|Moreno Garcia, V\|Diaz, E\|Burgos, E\|Gonzalez-Baron, M\|Feliu, J
PMID:	22229245

529.
Journal:	Am J Gastroenterol. 2012 Mar;107(3):460-9.
Title:	A novel pit pattern identifies the precursor of colorectal cancer derived from sessile serrated adenoma.
Author:	Kimura, Tomoaki\|Yamamoto, Eiichiro\|Yamano, Hiro-O\|Suzuki, Hiromu\|Kamimae, Seiko\|Nojima, Masanori\|Sawada, Takeshi\|Ashida, Masami\|Yoshikawa, Kenjiro\|Takagi, Ryo\|Kato, Ryusuke\|Harada, Taku\|Suzuki, Ryo\|Maruyama, Reo\|Kai, Masahiro\|Imai, Kohzoh\|Shinomura, Yasuh
PMID:	22233696

530.
Journal:	Transplantation. 2012 Mar 15;93(5):509-17.
Title:	Role of oncogenic pathways and KRAS/BRAF mutations in the behavior of colon adenocarcinoma in renal transplant patients.
Author:	Revuelta, Ignacio\|Moya-Rull, Daniel\|Garcia-Herrera, Adriana\|Rovira, Jordi\|Ayala de la Pena, Francisco\|Misiego, Antonio\|Guzman, Flavia\|Oppenheimer, Federico\|Albanell, Joan\|Campistol, Josep M
PMID:	22245873

531.
Journal:	Hematol Oncol. 2012 Dec;30(4):190-3.
Title:	Real-time PCR-based analysis of BRAF V600E mutation in low and intermediate grade lymphomas confirms frequent occurrence in hairy cell leukaemia.
Author:	Ewalt, Mark\|Nandula, Subhadra\|Phillips, Adrienne\|Alobeid, Bachir\|Murty, Vundavalli V\|Mansukhani, Mahesh M\|Bhagat, Govind
PMID:	22246856

532.
Journal:	Biochem Soc Trans. 2012 Feb;40(1):73-8.
Title:	Tumour cell responses to MEK1/2 inhibitors: acquired resistance and pathway remodelling.
Author:	Little, Annette S\|Balmanno, Kathryn\|Sale, Matthew J\|Smith, Paul D\|Cook, Simon J
PMID:	22260668

533.
Journal:	Clin Cancer Res. 2012 Apr 15;18(8):2316-25.
Title:	The clinical effect of the dual-targeting strategy involving PI3K/AKT/mTOR and RAS/MEK/ERK pathways in patients with advanced cancer.
Author:	Shimizu, Toshio\|Tolcher, Anthony W\|Papadopoulos, Kyriakos P\|Beeram, Muralidhar\|Rasco, Drew W\|Smith, Lon S\|Gunn, Shelly\|Smetzer, Leslie\|Mays, Theresa A\|Kaiser, Brianne\|Wick, Michael J\|Alvarez, Cathy\|Cavazos, Aracely\|Mangold, Gina L\|Patnaik, Amita
PMID:	22261800

534.
Journal:	Cell Cycle. 2012 Feb 1;11(3):594-603.
Title:	mTOR-independent 4E-BP1 phosphorylation is associated with cancer resistance to mTOR kinase inhibitors.
Author:	Zhang, Yanjie\|Zheng, X F Steven
PMID:	22262166

535.
Journal:	Recent Pat Anticancer Drug Discov. 2012 May 1;7(2):233-47.
Title:	Emerging role of cetuximab in the treatment of colorectal cancer.
Author:	Papa, Anselmo\|Rossi, Luigi\|Lo Russo, Giuseppe\|Giordani, Erika\|Spinelli, Gian Paolo\|Zullo, Angelo\|Petrozza, Vincenzo\|Tomao, Silverio
PMID:	22264223

536.
Journal:	Eur J Hum Genet. 2012 Jul;20(7):762-8.
Title:	MLH1 promoter hypermethylation in the analytical algorithm of Lynch syndrome: a cost-effectiveness study.
Author:	Gausachs, Mireia\|Mur, Pilar\|Corral, Julieta\|Pineda, Marta\|Gonzalez, Sara\|Benito, Llucia\|Menendez, Mireia\|Espinas, Josep Alfons\|Brunet, Joan\|Iniesta, Maria Dolores\|Gruber, Stephen B\|Lazaro, Conxi\|Blanco, Ignacio\|Capella, Gabriel
PMID:	22274583

537.
Journal:	Tumour Biol. 2012 Jun;33(3):857-64.
Title:	Clinical and molecular detection of inherited colorectal cancers in northeast Italy: a first prospective study of incidence of Lynch syndrome and MUTYH-related colorectal cancer in Italy.
Author:	Urso, E\|Agostini, M\|Pucciarelli, S\|Rugge, M\|Bertorelle, R\|Maretto, I\|Bedin, C\|D'Angelo, E\|Mescoli, C\|Zorzi, M\|Viel, A\|Bruttocao, G\|Ferraro, B\|Erroi, F\|Contin, P\|De Salvo, G L\|Nitti, D
PMID:	22278153

538.
Journal:	Nature. 2012 Jan 26;483(7387):100-3.
Title:	Unresponsiveness of colon cancer to BRAF(V600E) inhibition through feedback activation of EGFR.
Author:	Prahallad, Anirudh\|Sun, Chong\|Huang, Sidong\|Di Nicolantonio, Federica\|Salazar, Ramon\|Zecchin, Davide\|Beijersbergen, Roderick L\|Bardelli, Alberto\|Bernards, Rene
PMID:	22281684

539.
Journal:	Clin Cancer Res. 2012 Mar 15;18(6):1696-703.
Title:	Relationship between 18F-fluorodeoxyglucose accumulation and KRAS/BRAF mutations in colorectal cancer.
Author:	Kawada, Kenji\|Nakamoto, Yuji\|Kawada, Mayumi\|Hida, Koya\|Matsumoto, Takuya\|Murakami, Teppei\|Hasegawa, Suguru\|Togashi, Kaori\|Sakai, Yoshiharu
PMID:	22282467

540.
Journal:	Clin Colorectal Cancer. 2012 Jun;11(2):143-50.
Title:	PTEN gene expression and mutations in the PIK3CA gene as predictors of clinical benefit to anti-epidermal growth factor receptor antibody therapy in patients with KRAS wild-type metastatic colorectal cancer.
Author:	Sood, Arjun\|McClain, Danielle\|Maitra, Radhashree\|Basu-Mallick, Atrayee\|Seetharam, Raviraja\|Kaubisch, Andreas\|Rajdev, Lakshmi\|Mariadason, John M\|Tanaka, Kathryn\|Goel, Sanjay
PMID:	22285706

541.
Journal:	Int J Cancer. 2012 Oct 15;131(8):1790-9.
Title:	Colorectal serrated adenocarcinoma shows a different profile of oncogene mutations, MSI status and DNA repair protein expression compared to conventional and sporadic MSI-H carcinomas.
Author:	Garcia-Solano, J\|Conesa-Zamora, P\|Carbonell, P\|Trujillo-Santos, J\|Torres-Moreno D, D\|Pagan-Gomez, I\|Rodriguez-Braun, E\|Perez-Guillermo, M
PMID:	22287190

542.
Journal:	Pathologe. 2012 Feb;33(1):39-44.
Title:	[Prognostic marker profiles for risk of distant metastases in colorectal cancer].
Author:	Neumann, J\|Reu, S\|Kirchner, T
PMID:	22293788

543.
Journal:	Clin Cancer Res. 2012 Mar 15;18(6):1506-12.
Title:	Molecular pathways: microsatellite instability in colorectal cancer: prognostic, predictive, and therapeutic implications.
Author:	Sinicrope, Frank A\|Sargent, Daniel J
PMID:	22302899

544.
Journal:	Am J Surg Pathol. 2012 May;36(5):744-52.
Title:	BRAF-mutated, microsatellite-stable adenocarcinoma of the proximal colon: an aggressive adenocarcinoma with poor survival, mucinous differentiation, and adverse morphologic features.
Author:	Pai, Reetesh K\|Jayachandran, Priya\|Koong, Albert C\|Chang, Daniel T\|Kwok, Shirley\|Ma, Lisa\|Arber, Daniel A\|Balise, Raymond R\|Tubbs, Raymond R\|Shadrach, Bonnie\|Pai, Rish K
PMID:	22314188

545.
Journal:	Mol Cancer Ther. 2012 Apr;11(4):930-41.
Title:	CEP-32496: a novel orally active BRAF(V600E) inhibitor with selective cellular and in vivo antitumor activity.
Author:	James, Joyce\|Ruggeri, Bruce\|Armstrong, Robert C\|Rowbottom, Martin W\|Jones-Bolin, Susan\|Gunawardane, Ruwanthi N\|Dobrzanski, Pawel\|Gardner, Michael F\|Zhao, Hugh\|Cramer, Merryl D\|Hunter, Kathryn\|Nepomuceno, Ronald R\|Cheng, Mangeng\|Gitnick, Dana\|Yazdanian, Me
PMID:	22319199

546.
Journal:	Clin Cancer Res. 2012 Apr 15;18(8):2257-68.
Title:	Prognostic role of PIK3CA mutation in colorectal cancer: cohort study and literature review.
Author:	Liao, Xiaoyun\|Morikawa, Teppei\|Lochhead, Paul\|Imamura, Yu\|Kuchiba, Aya\|Yamauchi, Mai\|Nosho, Katsuhiko\|Qian, Zhi Rong\|Nishihara, Reiko\|Meyerhardt, Jeffrey A\|Fuchs, Charles S\|Ogino, Shuji
PMID:	22357840

547.
Journal:	J Med Genet. 2012 Mar;49(3):151-7.
Title:	Correlation of tumour BRAF mutations and MLH1 methylation with germline mismatch repair (MMR) gene mutation status: a literature review assessing utility of tumour features for MMR variant classification.
Author:	Parsons, Michael T\|Buchanan, Daniel D\|Thompson, Bryony\|Young, Joanne P\|Spurdle, Amanda B
PMID:	22368298

548.
Journal:	Expert Rev Mol Diagn. 2012 Mar;12(2):123-6.
Title:	KRAS mutational test for metastatic colorectal cancer patients: not just a technical problem.
Author:	Molinari, Francesca\|Frattini, Milo
PMID:	22369372

549.
Journal:	World J Surg Oncol. 2012 Feb 29;10:47.
Title:	ERK/pERK expression and B-raf mutations in colon adenocarcinomas: correlation with clinicopathological characteristics.
Author:	Levidou, Georgia\|Saetta, Angelica A\|Gigelou, Fanie\|Karlou, Maria\|Papanastasiou, Polyanthi\|Stamatelli, Angeliki\|Kavantzas, Nikolaos\|Michalopoulos, Nikolaos V\|Agrogiannis, George\|Patsouris, Efstratios\|Korkolopoulou, Penelope
PMID:	22376079

550.
Journal:	Clin Cancer Res. 2012 May 1;18(9):2515-25.
Title:	Inhibition of MEK and PI3K/mTOR suppresses tumor growth but does not cause tumor regression in patient-derived xenografts of RAS-mutant colorectal carcinomas.
Author:	Migliardi, Giorgia\|Sassi, Francesco\|Torti, Davide\|Galimi, Francesco\|Zanella, Eugenia R\|Buscarino, Michela\|Ribero, Dario\|Muratore, Andrea\|Massucco, Paolo\|Pisacane, Alberto\|Risio, Mauro\|Capussotti, Lorenzo\|Marsoni, Silvia\|Di Nicolantonio, Federica\|Bardelli,
PMID:	22392911

551.
Journal:	J Clin Oncol. 2012 Apr 20;30(12):1288-95.
Title:	Identification of a poor-prognosis BRAF-mutant-like population of patients with colon cancer.
Author:	Popovici, Vlad\|Budinska, Eva\|Tejpar, Sabine\|Weinrich, Scott\|Estrella, Heather\|Hodgson, Graeme\|Van Cutsem, Eric\|Xie, Tao\|Bosman, Fred T\|Roth, Arnaud D\|Delorenzi, Mauro
PMID:	22393095

552.
Journal:	J Crohns Colitis. 2012 Jul;6(6):647-54.
Title:	Molecular alterations in colitis-associated colorectal neoplasia: study from a low prevalence area using magnifying chromo colonoscopy.
Author:	Shivakumar, Bhadravathi Marigowda\|Kumar, Balasubramanian Lakshman\|Bhat, Ganesh\|Suvarna, Deepak\|Rao, Lakshmi\|Pai, C Ganesh\|Satyamoorthy, Kapaettu
PMID:	22398042

553.
Journal:	Int J Biol Markers. 2012 Jan-Mar;27(1):27-33.
Title:	Combined mutational analysis of KRAS, NRAS and BRAF genes in Indian patients with colorectal carcinoma.
Author:	Bagadi, Sarita B\|Sanghvi, Meera\|Nair, Sudish B\|Das, Bibhu R
PMID:	22427190

554.
Journal:	Gut. 2012 Jun;61(6):847-54.
Title:	Assessment of colorectal cancer molecular features along bowel subsites challenges the conception of distinct dichotomy of proximal versus distal colorectum.
Author:	Yamauchi, Mai\|Morikawa, Teppei\|Kuchiba, Aya\|Imamura, Yu\|Qian, Zhi Rong\|Nishihara, Reiko\|Liao, Xiaoyun\|Waldron, Levi\|Hoshida, Yujin\|Huttenhower, Curtis\|Chan, Andrew T\|Giovannucci, Edward\|Fuchs, Charles\|Ogino, Shuji
PMID:	22427238

555.
Journal:	Jpn J Clin Oncol. 2012 May;42(5):451-4.
Title:	Development of invasive colon cancer with microsatellite instability in a patient with hyperplastic polyposis syndrome.
Author:	Horii, Joichiro\|Kato, Jun\|Nagasaka, Takeshi\|Hiraoka, Sakiko\|Sun, Dong-Sheng\|Watanabe, Kazuo\|Fujita, Isao\|Toyokawa, Tatsuya\|Tomoda, Jun\|Yamamoto, Kazuhide
PMID:	22438407

556.
Journal:	Eur J Cancer. 2012 May;48(7):1108-15.
Title:	Concordance in KRAS and BRAF mutations in endoscopic biopsy samples and resection specimens of colorectal adenocarcinoma.
Author:	Krol, L C\|'t Hart, N A\|Methorst, N\|Knol, A J\|Prinsen, C\|Boers, J E
PMID:	22446020

557.
Journal:	Cancer Discov. 2012 Mar;2(3):227-35.
Title:	EGFR-mediated re-activation of MAPK signaling contributes to insensitivity of BRAF mutant colorectal cancers to RAF inhibition with vemurafenib.
Author:	Corcoran, Ryan B\|Ebi, Hiromichi\|Turke, Alexa B\|Coffee, Erin M\|Nishino, Michiya\|Cogdill, Alexandria P\|Brown, Ronald D\|Della Pelle, Patricia\|Dias-Santagata, Dora\|Hung, Kenneth E\|Flaherty, Keith T\|Piris, Adriano\|Wargo, Jennifer A\|Settleman, Jeffrey\|Mino-Kenu
PMID:	22448344

558.
Journal:	Crit Rev Oncog. 2012;17(1):97-121.
Title:	Aberrant B-Raf signaling in human cancer -- 10 years from bench to bedside.
Author:	Roring, Michael\|Brummer, Tilman
PMID:	22471666

559.
Journal:	J Clin Oncol. 2012 May 10;30(14):1620-7.
Title:	Multicenter randomized phase II clinical trial comparing neoadjuvant oxaliplatin, capecitabine, and preoperative radiotherapy with or without cetuximab followed by total mesorectal excision in patients with high-risk rectal cancer (EXPERT-C).
Author:	Dewdney, Alice\|Cunningham, David\|Tabernero, Josep\|Capdevila, Jaume\|Glimelius, Bengt\|Cervantes, Andres\|Tait, Diana\|Brown, Gina\|Wotherspoon, Andrew\|Gonzalez de Castro, David\|Chua, Yu Jo\|Wong, Rachel\|Barbachano, Yolanda\|Oates, Jacqueline\|Chau, Ian
PMID:	22473163

560.
Journal:	Mod Pathol. 2012 Aug;25(8):1128-39.
Title:	Clinicopathologic and molecular features of sporadic early-onset colorectal adenocarcinoma: an adenocarcinoma with frequent signet ring cell differentiation, rectal and sigmoid involvement, and adverse morphologic features.
Author:	Chang, Daniel T\|Pai, Rish K\|Rybicki, Lisa A\|Dimaio, Michael A\|Limaye, Maneesha\|Jayachandran, Priya\|Koong, Albert C\|Kunz, Pamela A\|Fisher, George A\|Ford, James M\|Welton, Mark\|Shelton, Andrew\|Ma, Lisa\|Arber, Daniel A\|Pai, Reetesh K
PMID:	22481281

561.
Journal:	Neoplasma. 2012;59(4):376-83.
Title:	Mutation pattern of KRAS and BRAF oncogenes in colorectal cancer patients.
Author:	Rako, I\|Jakic-Razumovic, J\|Katalinic, D\|Sertic, J\|Plestina, S
PMID:	22489692

562.
Journal:	Clin Cancer Res. 2012 Jun 1;18(11):3132-41.
Title:	Mutations in the Ras-Raf Axis underlie the prognostic value of CD133 in colorectal cancer.
Author:	Kemper, Kristel\|Versloot, Miranda\|Cameron, Katherine\|Colak, Selcuk\|de Sousa e Melo, Felipe\|de Jong, Joan H\|Bleackley, Joanne\|Vermeulen, Louis\|Versteeg, Rogier\|Koster, Jan\|Medema, Jan Paul
PMID:	22496204

563.
Journal:	Arch Surg. 2012 Aug;147(8):715-23.
Title:	Predictors of lymph node count in colorectal cancer resections: data from US nationwide prospective cohort studies.
Author:	Morikawa, Teppei\|Tanaka, Noriko\|Kuchiba, Aya\|Nosho, Katsuhiko\|Yamauchi, Mai\|Hornick, Jason L\|Swanson, Richard S\|Chan, Andrew T\|Meyerhardt, Jeffrey A\|Huttenhower, Curtis\|Schrag, Deborah\|Fuchs, Charles S\|Ogino, Shuji
PMID:	22508672

564.
Journal:	Am J Surg Pathol. 2012 Jun;36(6):876-82.
Title:	Phenotype and polyp landscape in serrated polyposis syndrome: a series of 100 patients from genetics clinics.
Author:	Rosty, Christophe\|Buchanan, Daniel D\|Walsh, Michael D\|Pearson, Sally-Ann\|Pavluk, Erika\|Walters, Rhiannon J\|Clendenning, Mark\|Spring, Kevin J\|Jenkins, Mark A\|Win, Aung K\|Hopper, John L\|Sweet, Kevin\|Frankel, Wendy L\|Aronson, Melyssa\|Gallinger, Steve\|Goldbla
PMID:	22510757

565.
Journal:	Curr Cancer Drug Targets. 2012 Sep;12(7):873-98.
Title:	A molecular signature for oncogenic BRAF in human colon cancer cells is revealed by microarray analysis.
Author:	Joyce, T\|Oikonomou, E\|Kosmidou, V\|Makrodouli, E\|Bantounas, I\|Avlonitis, S\|Zografos, G\|Pintzas, A
PMID:	22515520

566.
Journal:	J BUON. 2012 Jan-Mar;17(1):73-8.
Title:	Meta-analysis of the predictive value of KRAS mutations in treatment response using cetuximab in colorectal cancer.
Author:	Tsoukalas, N\|Tzovaras, A A\|Tolia, M\|Kostakis, I D\|Papakostidi, A\|Pistamaltzian, N\|Ardavanis, A
PMID:	22517696

567.
Journal:	Int J Epidemiol. 2012 Aug;41(4):1060-72. Epub 2012 Apr 24.
Title:	Body size and risk for colorectal cancers showing BRAF mutations or microsatellite instability: a pooled analysis.
Author:	Hughes, Laura A E\|Williamson, Elizabeth J\|van Engeland, Manon\|Jenkins, Mark A\|Giles, Graham G\|Hopper, John L\|Southey, Melissa C\|Young, Joanne P\|Buchanan, Daniel D\|Walsh, Michael D\|van den Brandt, Piet A\|Alexandra Goldbohm, R\|Weijenberg, Matty P\|English, D
PMID:	22531127

568.
Journal:	Expert Opin Investig Drugs. 2012 Jun;21(6):879-89.
Title:	Regorafenib for cancer.
Author:	Strumberg, Dirk\|Schultheis, Beate
PMID:	22577890

569.
Journal:	Clin Chim Acta. 2012 Oct 9;413(19-20):1605-11.
Title:	Characteristics and prevalence of KRAS, BRAF, and PIK3CA mutations in colorectal cancer by high-resolution melting analysis in Taiwanese population.
Author:	Hsieh, Li-Ling\|Er, Tze-Kiong\|Chen, Chih-Chieh\|Hsieh, Jan-Sing\|Chang, Jan-Gowth\|Liu, Ta-Chih
PMID:	22579930

570.
Journal:	PLoS One. 2012;7(5):e36653.
Title:	KRAS, BRAF and PIK3CA mutations and the loss of PTEN expression in Chinese patients with colorectal cancer.
Author:	Mao, Chen\|Zhou, Junhua\|Yang, Zuyao\|Huang, Yafang\|Wu, Xinyin\|Shen, Hong\|Tang, Jinling\|Chen, Qing
PMID:	22586484

571.
Journal:	Anticancer Res. 2012 May;32(5):1621-6.
Title:	Utility of cell-free tumour DNA for post-surgical follow-up of colorectal cancer patients.
Author:	Levy, Miroslav\|Benesova, Lucie\|Lipska, Ludmila\|Belsanova, Barbora\|Minarikova, Petra\|Veprekova, Gabriela\|Zavoral, Miroslav\|Minarik, Marek
PMID:	22593440

572.
Journal:	Expert Opin Biol Ther. 2012 Jun;12 Suppl 1:S209-15.
Title:	The importance of examining the proportion of circulating DNA originating from tumor, microenvironment and normal cells in colorectal cancer patients.
Author:	Mouliere, Florent\|Thierry, Alain R
PMID:	22594497

573.
Journal:	Food Funct. 2012 Aug;3(8):844-52.
Title:	Hypericum androsaemum water extract inhibits proliferation in human colorectal cancer cells through effects on MAP kinases and PI3K/Akt pathway.
Author:	Xavier, Cristina P R\|Lima, Cristovao F\|Fernandes-Ferreira, Manuel\|Pereira-Wilson, Cristina
PMID:	22596086

574.
Journal:	Lancet. 2012 May 19;379(9829):1893-901.
Title:	Dabrafenib in patients with melanoma, untreated brain metastases, and other solid tumours: a phase 1 dose-escalation trial.
Author:	Falchook, Gerald S\|Long, Georgina V\|Kurzrock, Razelle\|Kim, Kevin B\|Arkenau, Tobias H\|Brown, Michael P\|Hamid, Omid\|Infante, Jeffrey R\|Millward, Michael\|Pavlick, Anna C\|O'Day, Steven J\|Blackman, Samuel C\|Curtis, C Martin\|Lebowitz, Peter\|Ma, Bo\|Ouellet, Dani
PMID:	22608338

575.
Journal:	Ann Surg Oncol. 2012 Oct;19(11):3441-8.
Title:	Clinical outcomes of patients with microsatellite-unstable colorectal carcinomas depend on L1 methylation level.
Author:	Rhee, Ye-Young\|Kim, Mi Jung\|Bae, Jeong Mo\|Koh, Jae Moon\|Cho, Nam-Yun\|Juhnn, Yong-Sung\|Kim, Donguk\|Kang, Gyeong Hoon
PMID:	22618722

576.
Journal:	Nihon Rinsho. 2012 May;70(5):802-8.
Title:	[Biomarker for colorectal cancer].
Author:	Nagasaka, Takeshi\|Mori, Yoshiko\|Umeda, Yuzo\|Fujiwara, Toshiyoshi
PMID:	22620004

577.
Journal:	Gastroenterology. 2012 Sep;143(3):730-740.
Title:	A role for the epidermal growth factor receptor signaling in development of intestinal serrated polyps in mice and humans.
Author:	Bongers, Gerold\|Muniz, Luciana R\|Pacer, Michelle E\|Iuga, Alina C\|Thirunarayanan, Nanthakumar\|Slinger, Erik\|Smit, Martine J\|Reddy, E Premkumar\|Mayer, Lloyd\|Furtado, Glaucia C\|Harpaz, Noam\|Lira, Sergio A
PMID:	22643351

578.
Journal:	World J Gastroenterol. 2012 May 28;18(20):2452-61.
Title:	Serrated polyposis syndrome: molecular, pathological and clinical aspects.
Author:	Guarinos, Carla\|Sanchez-Fortun, Cristina\|Rodriguez-Soler, Maria\|Alenda, Cristina\|Paya, Artemio\|Jover, Rodrigo
PMID:	22654442

579.
Journal:	Front Oncol. 2012 Feb 27;2:7.
Title:	Stratification and Prognostic Relevance of Jass's Molecular Classification of Colorectal Cancer.
Author:	Zlobec, Inti\|Bihl, Michel P\|Foerster, Anja\|Rufle, Alex\|Terracciano, Luigi\|Lugli, Alessandro
PMID:	22655257

580.
Journal:	J Clin Oncol. 2012 Aug 20;30(24):2956-62.
Title:	Comparative genomic analysis of primary versus metastatic colorectal carcinomas.
Author:	Vakiani, Efsevia\|Janakiraman, Manickam\|Shen, Ronglai\|Sinha, Rileen\|Zeng, Zhaoshi\|Shia, Jinru\|Cercek, Andrea\|Kemeny, Nancy\|D'Angelica, Michael\|Viale, Agnes\|Heguy, Adriana\|Paty, Philip\|Chan, Timothy A\|Saltz, Leonard B\|Weiser, Martin\|Solit, David B
PMID:	22665543

581.
Journal:	PLoS One. 2012;7(5):e38033.
Title:	KRASness and PIK3CAness in patients with advanced colorectal cancer: outcome after treatment with early-phase trials with targeted pathway inhibitors.
Author:	Garrido-Laguna, Ignacio\|Hong, David S\|Janku, Filip\|Nguyen, Ly M\|Falchook, Gerald S\|Fu, Siqing\|Wheler, Jenifer J\|Luthra, Rajyalakshmi\|Naing, Aung\|Wang, Xuemei\|Kurzrock, Razelle
PMID:	22675430

582.
Journal:	PLoS One. 2012;7(6):e38422.
Title:	Histological and molecular evaluation of patient-derived colorectal cancer explants.
Author:	Uronis, Joshua M\|Osada, Takuya\|McCall, Shannon\|Yang, Xiao Yi\|Mantyh, Christopher\|Morse, Michael A\|Lyerly, H Kim\|Clary, Bryan M\|Hsu, David S
PMID:	22675560

583.
Journal:	Mod Pathol. 2012 Oct;25(10):1423-31.
Title:	Proximal colon cancers and the serrated pathway: a systematic analysis of precursor histology and BRAF mutation status.
Author:	Patil, Deepa T\|Shadrach, Bonnie L\|Rybicki, Lisa A\|Leach, Brandie H\|Pai, Rish K
PMID:	22684223

584.
Journal:	Am J Manag Care. 2012 May 1;18(5):e179-85.
Title:	Influence of patient preferences on the cost-effectiveness of screening for Lynch syndrome.
Author:	Wang, Grace\|Kuppermann, Miriam\|Kim, Benjamin\|Phillips, Kathryn A\|Ladabaum, Uri
PMID:	22694112

585.
Journal:	BMC Cancer. 2012 Jun 19;12:260.
Title:	Colon cancer molecular subtypes identified by expression profiling and associated to stroma, mucinous type and different clinical behavior.
Author:	Perez-Villamil, Beatriz\|Romera-Lopez, Alejandro\|Hernandez-Prieto, Susana\|Lopez-Campos, Guillermo\|Calles, Antonio\|Lopez-Asenjo, Jose-Antonio\|Sanz-Ortega, Julian\|Fernandez-Perez, Cristina\|Sastre, Javier\|Alfonso, Rosario\|Caldes, Trinidad\|Martin-Sanchez, Fern
PMID:	22712570

586.
Journal:	Small GTPases. 2012 Jan-Mar;3(1):34-9.
Title:	KRAS mutant colorectal tumors: past and present.
Author:	Brand, Toni M\|Wheeler, Deric L
PMID:	22714415

587.
Journal:	Mol Cancer Ther. 2012 Sep;11(9):2062-71.
Title:	Molecular profiling of patients with colorectal cancer and matched targeted therapy in phase I clinical trials.
Author:	Dienstmann, Rodrigo\|Serpico, Danila\|Rodon, Jordi\|Saura, Cristina\|Macarulla, Teresa\|Elez, Elena\|Alsina, Maria\|Capdevila, Jaume\|Perez-Garcia, Jose\|Sanchez-Olle, Gessami\|Aura, Claudia\|Prudkin, Ludmila\|Landolfi, Stefania\|Hernandez-Losa, Javier\|Vivancos, Ana\|T
PMID:	22723336

588.
Journal:	Oncol Lett. 2012 Mar;3(3):649-653.
Title:	Acquired/intratumoral mutation of KRAS during metastatic progression of colorectal carcinogenesis.
Author:	Otsuka, Kazunori\|Satoyoshi, Rika\|Nanjo, Hiroshi\|Miyazawa, Hideaki\|Abe, Yuki\|Tanaka, Masamitsu\|Yamamoto, Yuzo\|Shibata, Hiroyuki
PMID:	22740969

589.
Journal:	Ann Surg Oncol. 2012 Nov;19(12):3719-26.
Title:	Prognostic relevance of occult metastases detected by cytokeratin 20 and mucin 2 mRNA levels in sentinel lymph nodes from colon cancer patients.
Author:	Nordgard, Oddmund\|Oltedal, Satu\|Aasprong, Ole Gunnar\|Soreide, Jon Arne\|Soreide, Kjetil\|Tjensvoll, Kjersti\|Gilje, Bjornar\|Heikkila, Reino\|Guriby, Marianne\|Lothe, Ragnhild A\|Smaaland, Rune\|Korner, Hartwig
PMID:	22752373

590.
Journal:	Clin Cancer Res. 2012 Sep 1;18(17):4753-63.
Title:	Specific mutations in KRAS codons 12 and 13, and patient prognosis in 1075 BRAF wild-type colorectal cancers.
Author:	Imamura, Yu\|Morikawa, Teppei\|Liao, Xiaoyun\|Lochhead, Paul\|Kuchiba, Aya\|Yamauchi, Mai\|Qian, Zhi Rong\|Nishihara, Reiko\|Meyerhardt, Jeffrey A\|Haigis, Kevin M\|Fuchs, Charles S\|Ogino, Shuji
PMID:	22753589

591.
Journal:	In Vivo. 2012 Jul-Aug;26(4):537-47.
Title:	A comprehensive procedural approach to genotyping KRAS and BRAF from paraffin embedded tissues for diagnostic purposes.
Author:	Palmirotta, Raffaele\|Ludovici, Giorgia\|De Marchis, Maria Laura\|Leone, Barbara\|Formica, Vincenzo\|Ettorre, Giuseppe Maria\|Cavaliere, Francesco\|Della-Morte, David\|Ferroni, Patrizia\|Roselli, Mario\|Guadagni, Fiorella
PMID:	22773565

592.
Journal:	Proc Natl Acad Sci U S A. 2012 Jul 31;109(31):E2127-33.
Title:	Lung cancers with acquired resistance to EGFR inhibitors occasionally harbor BRAF gene mutations but lack mutations in KRAS, NRAS, or MEK1.
Author:	Ohashi, Kadoaki\|Sequist, Lecia V\|Arcila, Maria E\|Moran, Teresa\|Chmielecki, Juliann\|Lin, Ya-Lun\|Pan, Yumei\|Wang, Lu\|de Stanchina, Elisa\|Shien, Kazuhiko\|Aoe, Keisuke\|Toyooka, Shinichi\|Kiura, Katsuyuki\|Fernandez-Cuesta, Lynnette\|Fidias, Panos\|Yang, James Chi
PMID:	22773810

593.
Journal:	J Clin Pathol. 2012 Oct;65(10):924-7.
Title:	Qualities of sessile serrated adenoma/polyp/lesion and its borderline variant in the context of synchronous colorectal carcinoma.
Author:	Mohammadi, Mahin\|Kristensen, Michael Holmsgaard\|Nielsen, Hans Jorgen\|Bonde, Jesper Hansen\|Holck, Susanne
PMID:	22782936

594.
Journal:	Chemother Res Pract. 2012;2012:359041.
Title:	CpG Island Methylation, Microsatellite Instability, and BRAF Mutations and Their Clinical Application in the Treatment of Colon Cancer.
Author:	Wu, Christina\|Bekaii-Saab, Tanios
PMID:	22792460

595.
Journal:	Oncol Rep. 2012 Oct;28(4):1187-92.
Title:	KIF5B/RET fusion gene in surgically-treated adenocarcinoma of the lung.
Author:	Yokota, Keisuke\|Sasaki, Hidefumi\|Okuda, Katsuhiro\|Shimizu, Shigeki\|Shitara, Masayuki\|Hikosaka, Yu\|Moriyama, Satoru\|Yano, Motoki\|Fujii, Yoshitaka
PMID:	22797671

596.
Journal:	Histopathology. 2012 Nov;61(5):777-87.
Title:	The impact of CpG island methylator phenotype and microsatellite instability on tumour budding in colorectal cancer.
Author:	Zlobec, Inti\|Bihl, Michel P\|Foerster, Anja\|Rufle, Alex\|Lugli, Alessandro
PMID:	22803799

597.
Journal:	PLoS One. 2012;7(7):e40671.
Title:	Expression of Abelson interactor 1 (Abi1) correlates with inflammation, KRAS mutation and adenomatous change during colonic carcinogenesis.
Author:	Steinestel, Konrad\|Bruderlein, Silke\|Steinestel, Julie\|Markl, Bruno\|Schwerer, Michael J\|Arndt, Annette\|Kraft, Klaus\|Propper, Christian\|Moller, Peter
PMID:	22808230

598.
Journal:	J Cell Biol. 2012 Jul 23;198(2):185-94.
Title:	K-Ras and B-Raf oncogenes inhibit colon epithelial polarity establishment through up-regulation of c-myc.
Author:	Magudia, Kirti\|Lahoz, Aurelia\|Hall, Alan
PMID:	22826122

599.
Journal:	Eur J Cancer. 2012 Dec;48(18):3405-13.
Title:	Insulin-like growth factor 2 messenger RNA binding protein 3 (IGF2BP3) is a marker of unfavourable prognosis in colorectal cancer.
Author:	Lochhead, Paul\|Imamura, Yu\|Morikawa, Teppei\|Kuchiba, Aya\|Yamauchi, Mai\|Liao, Xiaoyun\|Qian, Zhi Rong\|Nishihara, Reiko\|Wu, Kana\|Meyerhardt, Jeffrey A\|Fuchs, Charles S\|Ogino, Shuji
PMID:	22840368

600.
Journal:	Expert Rev Mol Diagn. 2012 Jul;12(6):593-602.
Title:	Personalized medicine and pharmacogenetic biomarkers: progress in molecular oncology testing.
Author:	Ong, Frank S\|Das, Kingshuk\|Wang, Jay\|Vakil, Hana\|Kuo, Jane Z\|Blackwell, Wendell-Lamar B\|Lim, Stephen W\|Goodarzi, Mark O\|Bernstein, Kenneth E\|Rotter, Jerome I\|Grody, Wayne W
PMID:	22845480

601.
Journal:	Clin Transl Oncol. 2012 Oct;14(10):726-39.
Title:	Guidelines for biomarker testing in colorectal carcinoma (CRC): a national consensus of the Spanish Society of Pathology (SEAP) and the Spanish Society of Medical Oncology (SEOM).
Author:	Garcia-Alfonso, Pilar\|Salazar, Ramon\|Garcia-Foncillas, Jesus\|Musulen, Eva\|Garcia-Carbonero, Rocio\|Paya, Artemio\|Perez-Segura, Pedro\|Ramon y Cajal, Santiago\|Navarro, Samuel
PMID:	22855150

602.
Journal:	PLoS One. 2012;7(7):e42001.
Title:	A comprehensive characterization of genome-wide copy number aberrations in colorectal cancer reveals novel oncogenes and patterns of alterations.
Author:	Xie, Tao\|D' Ario, Giovanni\|Lamb, John R\|Martin, Eric\|Wang, Kai\|Tejpar, Sabine\|Delorenzi, Mauro\|Bosman, Fred T\|Roth, Arnaud D\|Yan, Pu\|Bougel, Stephanie\|Di Narzo, Antonio Fabio\|Popovici, Vlad\|Budinska, Eva\|Mao, Mao\|Weinrich, Scott L\|Rejto, Paul A\|Hodgson, J
PMID:	22860045

603.
Journal:	Oncotarget. 2012 Jul;3(7):700-8.
Title:	The response to PAK1 inhibitor IPA3 distinguishes between cancer cells with mutations in BRAF and Ras oncogenes.
Author:	Singhal, Ruchi\|Kandel, Eugene S
PMID:	22869096

604.
Journal:	PLoS One. 2012;7(8):e42274.
Title:	Prognostic impact of FoxP3+ regulatory T cells in relation to CD8+ T lymphocyte density in human colon carcinomas.
Author:	Yoon, Harry H\|Orrock, Jared M\|Foster, Nathan R\|Sargent, Daniel J\|Smyrk, Thomas C\|Sinicrope, Frank A
PMID:	22879926

605.
Journal:	Histopathology. 2012 Dec;61(6):1117-24.
Title:	The utility of diagnostic biopsy specimens for predictive molecular testing in colorectal cancer.
Author:	Fadhil, Wakkas\|Ibrahem, Salih\|Seth, Rashmi\|AbuAli, Ghada\|Ragunath, Krishna\|Kaye, Philip\|Ilyas, Mohammad
PMID:	22882224

606.
Journal:	Pathol Res Pract. 2012 Oct 15;208(10):592-7.
Title:	Influence of anatomical subsite on the incidence of microsatellite instability, and KRAS and BRAF mutation rates in patients with colon carcinoma.
Author:	Benedix, Frank\|Meyer, Frank\|Kube, Rainer\|Kropf, Siegfried\|Kuester, Doerthe\|Lippert, Hans\|Roessner, Albert\|Kruger, Sabine
PMID:	22898351

607.
Journal:	Cancer Epidemiol Biomarkers Prev. 2012 Oct;21(10):1792-8.
Title:	BRAF mutation status and survival after colorectal cancer diagnosis according to patient and tumor characteristics.
Author:	Phipps, Amanda I\|Buchanan, Daniel D\|Makar, Karen W\|Burnett-Hartman, Andrea N\|Coghill, Anna E\|Passarelli, Michael N\|Baron, John A\|Ahnen, Dennis J\|Win, Aung Ko\|Potter, John D\|Newcomb, Polly A
PMID:	22899730

608.
Journal:	Cancer Biol Ther. 2012 Nov;13(13):1235-43.
Title:	K-Ras gene mutation status as a prognostic and predictive factor in patients with colorectal cancer undergoing irinotecan- or oxaliplatin-based chemotherapy.
Author:	Stec, Rafal\|Bodnar, Lubomir\|Charkiewicz, Radoslaw\|Korniluk, Jan\|Rokita, Marta\|Smoter, Marta\|Ciechowicz, Marzena\|Chyczewski, Lech\|Niklinski, Jacek\|Kozlowski, Wojciech\|Szczylik, Cezary
PMID:	22909976

609.
Journal:	PLoS One. 2012;7(7):e41347.
Title:	Antitumoral efficacy of the protease inhibitor gabexate mesilate in colon cancer cells harbouring KRAS, BRAF and PIK3CA mutations.
Author:	Brandi, Giovanni\|Tavolari, Simona\|De Rosa, Francesco\|Di Girolamo, Stefania\|Agostini, Valentina\|Barbera, Maria Aurelia\|Frega, Giorgio\|Biasco, Guido
PMID:	22911782

610.
Journal:	Int J Oncol. 2012 Nov;41(5):1855-62.
Title:	Combination therapy targeting Raf-1 and MEK causes apoptosis of HCT116 colon cancer cells.
Author:	Subramanian, Romesh R\|Yamakawa, Akio
PMID:	22922669

611.
Journal:	J Transl Med. 2012 Aug 27;10:173.
Title:	Characterization of CDKN2A(p16) methylation and impact in colorectal cancer: systematic analysis using pyrosequencing.
Author:	Bihl, Michel P\|Foerster, Anja\|Lugli, Alessandro\|Zlobec, Inti
PMID:	22925370

612.
Journal:	Stud Health Technol Inform. 2012;179:143-54.
Title:	Digital pathology in personalized cancer therapy.
Author:	Slodkowska, Janina\|Garcia-Rojo, Marcial
PMID:	22925795

613.
Journal:	Genes Chromosomes Cancer. 2012 Dec;51(12):1133-43.
Title:	Aberrant promoter methylation of beta-1,4 galactosyltransferase 1 as potential cancer-specific biomarker of colorectal tumors.
Author:	Poeta, Maria Luana\|Massi, Emanuela\|Parrella, Paola\|Pellegrini, Pasquale\|De Robertis, Mariangela\|Copetti, Massimiliano\|Rabitti, Carla\|Perrone, Giuseppe\|Muda, Andrea Onetti\|Molinari, Francesca\|Zanellato, Elena\|Crippa, Stefano\|Caputo, Damiano\|Caricato, Marco
PMID:	22927297

614.
Journal:	J Transl Med. 2012 Aug 29;10:178.
Title:	Prevalence of KRAS, BRAF, and PIK3CA somatic mutations in patients with colorectal carcinoma may vary in the same population: clues from Sardinia.
Author:	Palomba, Grazia\|Colombino, Maria\|Contu, Antonio\|Massidda, Bruno\|Baldino, Giovanni\|Pazzola, Antonio\|Ionta, MariaTeresa\|Capelli, Francesca\|Trova, Vittorio\|Sedda, Tito\|Sanna, Giovanni\|Tanda, Francesco\|Budroni, Mario\|Palmieri, Giuseppe\|Cossu, Antonio\|Contu, M
PMID:	22931052

615.
Journal:	Arch Pathol Lab Med. 2012 Sep;136(9):983-92.
Title:	High-resolution melting analysis as a sensitive prescreening diagnostic tool to detect KRAS , BRAF , PIK3CA , and AKT1 mutations in formalin-fixed, paraffin-embedded tissues.
Author:	Ney, Jasmin Teresa\|Froehner, Stefanie\|Roesler, Angelika\|Buettner, Reinhard\|Merkelbach-Bruse, Sabine
PMID:	22938585

616.
Journal:	J Oncol Pract. 2012 May;8(3 Suppl):e24s-30s.
Title:	Influence of patient preferences on the cost-effectiveness of screening for lynch syndrome.
Author:	Wang, Grace\|Kuppermann, Miriam\|Kim, Benjamin\|Phillips, Kathryn A\|Ladabaum, Uri
PMID:	22942831

617.
Journal:	Exp Ther Med. 2012 Mar;3(3):547-549.
Title:	Possibility of molecular targeting therapy for the treatment of cancer of unknown primary origin by analysis of intracellular signaling molecules.
Author:	Ohta, Shoichiro\|Cho, Yukiko\|Shibata, Masaharu\|Nagai, Kimihiro\|Iijima, Tatsuo\|Saito, Hitoaki\|Asakura, Hirotaka\|Kojima, Hiroshi
PMID:	22969927

618.
Journal:	Am J Pathol. 2012 Nov;181(5):1847-61.
Title:	Molecular dissection of premalignant colorectal lesions reveals early onset of the CpG island methylator phenotype.
Author:	Yamamoto, Eiichiro\|Suzuki, Hiromu\|Yamano, Hiro-o\|Maruyama, Reo\|Nojima, Masanori\|Kamimae, Seiko\|Sawada, Takeshi\|Ashida, Masami\|Yoshikawa, Kenjiro\|Kimura, Tomoaki\|Takagi, Ryo\|Harada, Taku\|Suzuki, Ryo\|Sato, Akiko\|Kai, Masahiro\|Sasaki, Yasushi\|Tokino, Takashi
PMID:	22995252

619.
Journal:	Oncotarget. 2012 Sep;3(9):907-8.
Title:	Mutation specific antibodies: tool or dinosaur?
Author:	von Deimling, Andreas\|Sahm, Felix\|Capper, David
PMID:	23006938

620.
Journal:	Br J Surg. 2012 Nov;99(11):1575-82.
Title:	KRAS status and outcome of liver resection after neoadjuvant chemotherapy including bevacizumab.
Author:	Stremitzer, S\|Stift, J\|Gruenberger, B\|Tamandl, D\|Aschacher, T\|Wolf, B\|Wrba, F\|Gruenberger, T
PMID:	23027075

621.
Journal:	J BUON. 2012 Jul-Sep;17(3):575-80.
Title:	KRAS and BRAF mutations in Serbian patients with colorectal cancer.
Author:	Jakovljevic, K\|Malisic, E\|Cavic, M\|Krivokuca, A\|Dobricic, J\|Jankovic, R
PMID:	23033302

622.
Journal:	Clin Cancer Res. 2012 Dec 1;18(23):6531-41.
Title:	Mutation profiling and microsatellite instability in stage II and III colon cancer: an assessment of their prognostic and oxaliplatin predictive value.
Author:	Gavin, Patrick G\|Colangelo, Linda H\|Fumagalli, Debora\|Tanaka, Noriko\|Remillard, Matthew Y\|Yothers, Greg\|Kim, Chungyeul\|Taniyama, Yusuke\|Kim, Seung Il\|Choi, Hyun Joo\|Blackmon, Nicole L\|Lipchik, Corey\|Petrelli, Nicholas J\|O'Connell, Michael J\|Wolmark, Norma
PMID:	23045248

623.
Journal:	Oncotarget. 2012 Oct;3(10):1182-93.
Title:	Up-regulation of c-MYC and SIRT1 expression correlates with malignant transformation in the serrated route to colorectal cancer.
Author:	Kriegl, Lydia\|Vieth, Michael\|Kirchner, Thomas\|Menssen, Antje
PMID:	23045412

624.
Journal:	PLoS One. 2012;7(9):e45357.
Title:	A high degree of LINE-1 hypomethylation is a unique feature of early-onset colorectal cancer.
Author:	Antelo, Marina\|Balaguer, Francesc\|Shia, Jinru\|Shen, Yan\|Hur, Keun\|Moreira, Leticia\|Cuatrecasas, Miriam\|Bujanda, Luis\|Giraldez, Maria Dolores\|Takahashi, Masanobu\|Cabanne, Ana\|Barugel, Mario Edmundo\|Arnold, Mildred\|Roca, Enrique Luis\|Andreu, Montserrat\|Cast
PMID:	23049789

625.
Journal:	Clin Exp Metastasis. 2012 Oct;29(7):821-39.
Title:	Meeting the biologic challenge of colorectal metastases.
Author:	Wanebo, Harold J\|LeGolvan, Mark\|Paty, Philip B\|Saha, Sukamal\|Zuber, Markus\|D'Angelica, Michael I\|Kemeny, Nancey E
PMID:	23053740

626.
Journal:	Onco Targets Ther. 2012;5:199-211.
Title:	Critical appraisal of bevacizumab in the treatment of metastatic colorectal cancer.
Author:	Zoratto, Federica\|Rossi, Luigi\|Zullo, Angelo\|Papa, Anselmo\|Zaccarelli, Eleonora\|Tomao, Luigi\|Giordani, Erika\|Colonna, Maria\|Baiano, Giovanni\|Tomao, Silverio
PMID:	23055745

627.
Journal:	PLoS One. 2012;7(10):e47054.
Title:	The prognostic value of BRAF mutation in colorectal cancer and melanoma: a systematic review and meta-analysis.
Author:	Safaee Ardekani, Gholamreza\|Jafarnejad, Seyed Mehdi\|Tan, Larry\|Saeedi, Ardavan\|Li, Gang
PMID:	23056577

628.
Journal:	Nutr Cancer. 2012;64(7):899-910.
Title:	Associations between intake of folate and related micronutrients with molecularly defined colorectal cancer risks in the Iowa Women's Health Study.
Author:	Razzak, Anthony A\|Oxentenko, Amy S\|Vierkant, Robert A\|Tillmans, Lori S\|Wang, Alice H\|Weisenberger, Daniel J\|Laird, Peter W\|Lynch, Charles F\|Anderson, Kristin E\|French, Amy J\|Haile, Robert W\|Harnack, Lisa J\|Potter, John D\|Slager, Susan L\|Smyrk, Thomas C\|Th
PMID:	23061900

629.
Journal:	Bioorg Med Chem. 2012 Nov 15;20(22):6724-31.
Title:	Synthesis and evaluation of apoptosis induction of thienopyrimidine compounds on KRAS and BRAF mutated colorectal cancer cell lines.
Author:	Pedeboscq, Stephane\|Gravier, Denis\|Casadebaig, Francoise\|Hou, Genevieve\|Gissot, Arnaud\|Rey, Christophe\|Ichas, Francois\|De Giorgi, Francesca\|Lartigue, Lydia\|Pometan, Jean-Paul
PMID:	23063521

630.
Journal:	World J Gastroenterol. 2012 Oct 7;18(37):5171-80.
Title:	KRAS mutation testing in metastatic colorectal cancer.
Author:	Tan, Cong\|Du, Xiang
PMID:	23066310

631.
Journal:	Sci Signal. 2012 Oct 16;5(246):pe46.
Title:	The response of cancers to BRAF inhibition underscores the importance of cancer systems biology.
Author:	Stites, Edward C
PMID:	23074264

632.
Journal:	N Engl J Med. 2012 Oct 25;367(17):1596-606.
Title:	Aspirin use, tumor PIK3CA mutation, and colorectal-cancer survival.
Author:	Liao, Xiaoyun\|Lochhead, Paul\|Nishihara, Reiko\|Morikawa, Teppei\|Kuchiba, Aya\|Yamauchi, Mai\|Imamura, Yu\|Qian, Zhi Rong\|Baba, Yoshifumi\|Shima, Kaori\|Sun, Ruifang\|Nosho, Katsuhiko\|Meyerhardt, Jeffrey A\|Giovannucci, Edward\|Fuchs, Charles S\|Chan, Andrew T\|Ogino
PMID:	23094721

633.
Journal:	Ann Surg. 2012 Nov;256(5):763-71; discussion 771.
Title:	Integrative marker analysis allows risk assessment for metastasis in stage II colon cancer.
Author:	Nitsche, Ulrich\|Rosenberg, Robert\|Balmert, Alexander\|Schuster, Tibor\|Slotta-Huspenina, Julia\|Herrmann, Pia\|Bader, Franz G\|Friess, Helmut\|Schlag, Peter M\|Stein, Ulrike\|Janssen, Klaus-Peter
PMID:	23095620

634.
Journal:	World J Gastroenterol. 2012 Oct 21;18(39):5551-9.
Title:	MUC5AC/beta-catenin expression and KRAS gene alteration in laterally spreading colorectal tumors.
Author:	Nakae, Kosaburo\|Mitomi, Hiroyuki\|Saito, Tsuyoshi\|Takahashi, Michiko\|Morimoto, Takashi\|Hidaka, Yasuhiro\|Sakamoto, Naoto\|Yao, Takashi\|Watanabe, Sumio
PMID:	23112547

635.
Journal:	Eur J Gastroenterol Hepatol. 2012 Dec;24(12):1430-7.
Title:	Colorectal neuroendocrine carcinomas and adenocarcinomas share oncogenic pathways. A clinico-pathologic study of 12 cases.
Author:	Karkouche, Raymond\|Bachet, Jean-Baptiste\|Sandrini, Jeremy\|Mitry, Emmanuel\|Penna, Christophe\|Cote, Jean-Francois\|Blons, Helene\|Penault-Llorca, Frederique\|Rougier, Philippe\|Saint Andre, Jean-Paul\|Emile, Jean-Francois
PMID:	23114745

636.
Journal:	Int J Biol Markers. 2012 Dec 27;27(4):e366-74.
Title:	Survey of KRAS, BRAF and PIK3CA mutational status in 209 consecutive Italian colorectal cancer patients.
Author:	Bozzao, Cristina\|Varvara, Dora\|Piglionica, Marilidia\|Bagnulo, Rosanna\|Forte, Giovanna\|Patruno, Margherita\|Russo, Silvana\|Piscitelli, Domenico\|Stella, Alessandro\|Resta, Nicoletta
PMID:	23125007

637.
Journal:	J Natl Compr Canc Netw. 2012 Nov 1;10(11):1456-8.
Title:	BRAF mutations in colorectal cancer: clinical relevance and role in targeted therapy.
Author:	Yaeger, Rona\|Saltz, Leonard
PMID:	23138171

638.
Journal:	Gan To Kagaku Ryoho. 2012 Nov;39(11):1618-25.
Title:	[Predictive biomarkers for anti-EGFR antibodies].
Author:	Bando, Hideaki\|Yoshino, Takayuki
PMID:	23152013

639.
Journal:	Oncotarget. 2012 Nov;3(11):1348-55.
Title:	Loss of expression of the double strand break repair protein ATM is associated with worse prognosis in colorectal cancer and loss of Ku70 expression is associated with CIN.
Author:	Beggs, Andrew D\|Domingo, Enric\|McGregor, Megan\|Presz, Mikael\|Johnstone, Elaine\|Midgley, Rachel\|Kerr, David\|Oukrif, Dahmane\|Novelli, Marco\|Abulafi, Muti\|Hodgson, Shirley V\|Fadhil, Wakkas\|Ilyas, Mohammad\|Tomlinson, Ian P M
PMID:	23154512

640.
Journal:	Zhonghua Bing Li Xue Za Zhi. 2012 Sep;41(9):579-83.
Title:	[Mutations of KRAS and BRAF in Chinese patients with colorectal carcinoma: analyses of 966 cases].
Author:	Gao, Jing\|Sun, Zhi-wei\|Li, Yan-yan\|Shen, Lin
PMID:	23157823

641.
Journal:	Zhonghua Bing Li Xue Za Zhi. 2012 Sep;41(9):584-9.
Title:	[KRAS and BRAF gene mutations in correlation with clinicopathologic features of colorectal carcinoma in Chinese].
Author:	Zhu, Xiao-li\|Cai, Xu\|Zhang, Ling\|Yang, Fei\|Sheng, Wei-qi\|Lu, Yong-ming\|Du, Xiang\|Zhou, Xiao-yan
PMID:	23157824

642.
Journal:	Zhonghua Bing Li Xue Za Zhi. 2012 Sep;41(9):590-4.
Title:	[Detection of KRAS, BRAF, PIK3CA and EGFR gene mutations in colorectal carcinoma].
Author:	Ling, Yun\|Ying, Jian-ming\|Qiu, Tian\|Shan, Ling\|Guo, Lei\|Lu, Ning
PMID:	23157825

643.
Journal:	Cell. 2012 Nov 21;151(5):937-50.
Title:	MED12 controls the response to multiple cancer drugs through regulation of TGF-beta receptor signaling.
Author:	Huang, Sidong\|Holzel, Michael\|Knijnenburg, Theo\|Schlicker, Andreas\|Roepman, Paul\|McDermott, Ultan\|Garnett, Mathew\|Grernrum, Wipawadee\|Sun, Chong\|Prahallad, Anirudh\|Groenendijk, Floris H\|Mittempergher, Lorenza\|Nijkamp, Wouter\|Neefjes, Jacques\|Salazar, Ramo
PMID:	23178117

644.
Journal:	Proc Natl Acad Sci U S A. 2012 Dec 18;109(51):21046-51.
Title:	Direct and immune mediated antibody targeting of ERBB receptors in a colorectal cancer cell-line panel.
Author:	Ashraf, Shazad Q\|Nicholls, Angela M\|Wilding, Jennifer L\|Ntouroupi, Triantafyllia G\|Mortensen, Neil J\|Bodmer, Walter F
PMID:	23213241

645.
Journal:	PLoS One. 2012;7(11):e50806.
Title:	Tumor phosphatidylinositol-3-kinase signaling and development of metastatic disease in locally advanced rectal cancer.
Author:	Ree, Anne Hansen\|Kristensen, Annette Torgunrud\|Saelen, Marie Gron\|de Wijn, Rik\|Edvardsen, Hege\|Jovanovic, Jovana\|Abrahamsen, Torveig Weum\|Dueland, Svein\|Flatmark, Kjersti
PMID:	23226389

646.
Journal:	PLoS One. 2012;7(12):e51449.
Title:	Synergistic effects of combined Wnt/KRAS inhibition in colorectal cancer cells.
Author:	Mologni, Luca\|Brussolo, Stefania\|Ceccon, Monica\|Gambacorti-Passerini, Carlo
PMID:	23227266

647.
Journal:	Clin Transl Gastroenterol. 2012 Jan 5;3:e6.
Title:	Prevalence of different subtypes of serrated polyps and risk of synchronous advanced colorectal neoplasia in average-risk population undergoing first-time colonoscopy.
Author:	Buda, Andrea\|De Bona, Manuela\|Dotti, Isabella\|Piselli, Pierluca\|Zabeo, Eva\|Barbazza, Renzo\|Bellumat, Angelo\|Valiante, Flavio\|Nardon, Ermanno\|Probert, Chris S\|Pignatelli, Massimo\|Stanta, Giorgio\|Sturniolo, Giacomo Carlo\|De Boni, Michele
PMID:	23238028

648.
Journal:	PLoS One. 2012;7(12):e52485.
Title:	Establishment, characterization and chemosensitivity of three mismatch repair deficient cell lines from sporadic and inherited colorectal carcinomas.
Author:	Maletzki, Claudia\|Stier, Saskia\|Gruenert, Ulrike\|Gock, Michael\|Ostwald, Christiane\|Prall, Friedrich\|Linnebacher, Michael
PMID:	23300683

649.
Journal:	Asian Pac J Cancer Prev. 2012;13(11):5599-603.
Title:	Mutational analysis of key EGFR pathway genes in Chinese breast cancer patients.
Author:	Tong, Lin\|Yang, Xue-Xi\|Liu, Min-Feng\|Yao, Guang-Yu\|Dong, Jian-Yu\|Ye, Chang-Sheng\|Li, Ming
PMID:	23317280

650.
Journal:	Transl Oncol. 2012 Dec;5(6):430-6. Epub 2012 Dec 1.
Title:	Analysis of the BRAF(V600E) Mutation in Central Nervous System Tumors.
Author:	Myung, Jae Kyung\|Cho, Hwajin\|Park, Chul-Kee\|Kim, Seung-Ki\|Lee, Se-Hoon\|Park, Sung-Hye
PMID:	23323158

651.
Journal:	Rinsho Byori. 2012 Oct;60(10):976-81.
Title:	[Genetic and epigenetic changes in colorectal cancer and genetic testing for personalized medicine].
Author:	Suehiro, Yutaka\|Hinoda, Yuji
PMID:	23323463

652.
Journal:	Front Genet. 2013 Jan 17;3:312.
Title:	High-resolution melting analysis of the common c.1905+1G>A mutation causing dihydropyrimidine dehydrogenase deficiency and lethal 5-fluorouracil toxicity.
Author:	Borras, Emma\|Dotor, Emma\|Arcusa, Angels\|Gamundi, Maria J\|Hernan, Imma\|de Sousa Dias, Miguel\|Mane, Begona\|Agundez, Jose A G\|Blanca, Miguel\|Carballo, Miguel
PMID:	23335937

653.
Journal:	Acta Chir Iugosl. 2012;59(2):31-8.
Title:	Colorectal carcinoma under microscopy: patohistology or much more?
Author:	Knezevic-Usaj, Slavica\|Zivkovic-Kapicl, Ratjana\|Panjkovic, Milana\|Klem, Istvan\|Eri, Zivka
PMID:	23373356

654.
Journal:	Yao Xue Xue Bao. 2012 Dec;47(12):1567-74.
Title:	[Progress of anti-tumor study based on BRAF].
Author:	Yan, Gui-Rui\|Xu, Zhi-Jian\|Wang, He-Yao\|Zhu, Wei-Liang
PMID:	23460959

655.
Journal:	Oncogene. 2013 Jan 31;32(5):564-76.
Title:	Oncogenic KRAS and BRAF activation of the MEK/ERK signaling pathway promotes expression of dual-specificity phosphatase 4 (DUSP4/MKP2) resulting in nuclear ERK1/2 inhibition.
Author:	Cagnol, S\|Rivard, N
PMID:	22430215

656.
Journal:	Int J Clin Oncol. 2013 Aug;18(4):670-7.
Title:	Clinical usefulness of KRAS, BRAF, and PIK3CA mutations as predictive markers of cetuximab efficacy in irinotecan- and oxaliplatin-refractory Japanese patients with metastatic colorectal cancer.
Author:	Soeda, Hiroshi\|Shimodaira, Hideki\|Watanabe, Mika\|Suzuki, Takao\|Gamoh, Makio\|Mori, Takahiro\|Komine, Keigo\|Iwama, Noriyuki\|Kato, Shunsuke\|Ishioka, Chikashi
PMID:	22638623

657.
Journal:	Crit Rev Oncol Hematol. 2013 Jan;85(1):45-81.
Title:	Prognostic and predictive biomarkers for epidermal growth factor receptor-targeted therapy in colorectal cancer: beyond KRAS mutations.
Author:	Custodio, Ana\|Feliu, Jaime
PMID:	22647972

658.
Journal:	Int J Radiat Oncol Biol Phys. 2013 Jan 1;85(1):201-7.
Title:	KRAS mutation status and clinical outcome of preoperative chemoradiation with cetuximab in locally advanced rectal cancer: a pooled analysis of 2 phase II trials.
Author:	Kim, Sun Young\|Shim, Eun Kyung\|Yeo, Hyun Yang\|Baek, Ji Yeon\|Hong, Yong Sang\|Kim, Dae Yong\|Kim, Tae Won\|Kim, Jee Hyun\|Im, Seock-Ah\|Jung, Kyung Hae\|Chang, Hee Jin
PMID:	22672749

659.
Journal:	Cancer. 2013 Jan 15;119(2):266-76.
Title:	Genetic and epigenetic alterations in primary colorectal cancers and related lymph node and liver metastases.
Author:	Miranda, Elena\|Bianchi, Paolo\|Destro, Annarita\|Morenghi, Emanuela\|Malesci, Alberto\|Santoro, Armando\|Laghi, Luigi\|Roncalli, Massimo
PMID:	22786759

660.
Journal:	Gut. 2013 Apr;62(4):540-9.
Title:	A combined oncogenic pathway signature of BRAF, KRAS and PI3KCA mutation improves colorectal cancer classification and cetuximab treatment prediction.
Author:	Tian, Sun\|Simon, Iris\|Moreno, Victor\|Roepman, Paul\|Tabernero, Josep\|Snel, Mireille\|van't Veer, Laura\|Salazar, Ramon\|Bernards, Rene\|Capella, Gabriel
PMID:	22798500

661.
Journal:	J Pathol. 2013 Jan;229(1):99-110.
Title:	MLH1-silenced and non-silenced subgroups of hypermutated colorectal carcinomas have distinct mutational landscapes.
Author:	Donehower, Lawrence A\|Creighton, Chad J\|Schultz, Nikolaus\|Shinbrot, Eve\|Chang, Kyle\|Gunaratne, Preethi H\|Muzny, Donna\|Sander, Chris\|Hamilton, Stanley R\|Gibbs, Richard A\|Wheeler, David
PMID:	22899370

662.
Journal:	Mod Pathol. 2013 Feb;26(2):302-13.
Title:	Combined analysis of KRAS and PIK3CA mutations, MET and PTEN expression in primary tumors and corresponding metastases in colorectal cancer.
Author:	Voutsina, Alexandra\|Tzardi, Maria\|Kalikaki, Aristea\|Zafeiriou, Zafeiris\|Papadimitraki, Elsa\|Papadakis, Michael\|Mavroudis, Dimitris\|Georgoulias, Vassilis
PMID:	22936063

663.
Journal:	Hum Mutat. 2013 Jan;34(1):200-9.
Title:	A multifactorial likelihood model for MMR gene variant classification incorporating probabilities based on sequence bioinformatics and tumor characteristics: a report from the Colon Cancer Family Registry.
Author:	Thompson, Bryony A\|Goldgar, David E\|Paterson, Carol\|Clendenning, Mark\|Walters, Rhiannon\|Arnold, Sven\|Parsons, Michael T\|Michael D, Walsh\|Gallinger, Steven\|Haile, Robert W\|Hopper, John L\|Jenkins, Mark A\|Lemarchand, Loic\|Lindor, Noralane M\|Newcomb, Polly A\|
PMID:	22949379

664.
Journal:	Ann Surg Oncol. 2013 Apr;20(4):1395-402.
Title:	The rs6983267 SNP is associated with MYC transcription efficiency, which promotes progression and worsens prognosis of colorectal cancer.
Author:	Takatsuno, Yasushi\|Mimori, Koshi\|Yamamoto, Ken\|Sato, Tetsuya\|Niida, Atsushi\|Inoue, Hiroshi\|Imoto, Seiya\|Kawano, Shuhei\|Yamaguchi, Rui\|Toh, Hiroyuki\|Iinuma, Hisae\|Ishimaru, Shinya\|Ishii, Hideshi\|Suzuki, Sadao\|Tokudome, Shinkan\|Watanabe, Masahiko\|Tanaka, Ju
PMID:	22976378

665.
Journal:	J Cell Biochem. 2013 Mar;114(3):514-24.
Title:	Molecular diagnostics and personalized medicine in oncology: challenges and opportunities.
Author:	Normanno, Nicola\|Rachiglio, Anna Maria\|Roma, Cristin\|Fenizia, Francesca\|Esposito, Claudia\|Pasquale, Raffaella\|La Porta, Maria Libera\|Iannaccone, Alessia\|Micheli, Filippo\|Santangelo, Michele\|Bergantino, Francesca\|Costantini, Susan\|De Luca, Antonella
PMID:	22991232

666.
Journal:	J Hepatobiliary Pancreat Sci. 2013 Feb;20(2):223-33.
Title:	Poor prognosis of KRAS or BRAF mutant colorectal liver metastasis without microsatellite instability.
Author:	Umeda, Yuzo\|Nagasaka, Takeshi\|Mori, Yoshiko\|Sadamori, Hiroshi\|Sun, Dong-Sheng\|Shinoura, Susumu\|Yoshida, Ryuich\|Satoh, Daisuke\|Nobuoka, Daisuke\|Utsumi, Masashi\|Yoshida, Kazuhiro\|Yagi, Takahito\|Fujiwara, Toshiyoshi
PMID:	23010994

667.
Journal:	Int J Cancer. 2013 Apr 15;132(8):1800-10.
Title:	Molecular patterns in the evolution of serrated lesion of the colorectum.
Author:	Gaiser, Timo\|Meinhardt, Sandra\|Hirsch, Daniela\|Killian, Jonathan Keith\|Gaedcke, Jochen\|Jo, Peter\|Ponsa, Immaculada\|Miro, Rosa\|Ruschoff, Josef\|Seitz, Gerhard\|Hu, Yue\|Camps, Jordi\|Ried, Thomas
PMID:	23011871

668.
Journal:	J Cancer Res Clin Oncol. 2013 Feb;139(2):201-9.
Title:	KRAS p.G13D mutations are associated with sensitivity to anti-EGFR antibody treatment in colorectal cancer cell lines.
Author:	Messner, Isabelle\|Cadeddu, Giuseppe\|Huckenbeck, Wolfgang\|Knowles, Helen J\|Gabbert, Helmut E\|Baldus, Stephan E\|Schaefer, Karl-Ludwig
PMID:	23015072

669.
Journal:	Neoplasma. 2013;60(1):83-91.
Title:	Bevacizumab in combination with chemotherapy in the first-line treatment of metastatic colorectal carcinoma.
Author:	Usakova, V\|Sevcikova, K\|Usak, J\|Bartosova, Z\|Mikulova, M\|Spanik, S
PMID:	23067221

670.
Journal:	Genes Chromosomes Cancer. 2013 Feb;52(2):140-9.
Title:	Association between genomic alterations and metastatic behavior of colorectal cancer identified by array-based comparative genomic hybridization.
Author:	Sawada, Takeshi\|Yamamoto, Eiichiro\|Suzuki, Hiromu\|Nojima, Masanori\|Maruyama, Reo\|Shioi, Yoshihiro\|Akasaka, Risaburo\|Kamimae, Seiko\|Harada, Taku\|Ashida, Masami\|Kai, Masahiro\|Adachi, Yasushi\|Yamamoto, Hiroyuki\|Imai, Kohzoh\|Toyota, Minoru\|Itoh, Fumio\|Sugai,
PMID:	23073979

671.
Journal:	J Hum Genet. 2013 Jan;58(1):11-5.
Title:	Protein tyrosine phosphatase receptor-like genes are frequently hypermethylated in sporadic colorectal cancer.
Author:	Laczmanska, Izabela\|Karpinski, Pawel\|Bebenek, Marek\|Sedziak, Tomasz\|Ramsey, David\|Szmida, Elzbieta\|Sasiadek, Maria M
PMID:	23096495

672.
Journal:	Int J Cancer. 2013 May 15;132(10):2303-15.
Title:	Non-CpG island promoter hypomethylation and miR-149 regulate the expression of SRPX2 in colorectal cancer.
Author:	Oster, Bodil\|Linnet, Lene\|Christensen, Lise Lotte\|Thorsen, Kasper\|Ongen, Halit\|Dermitzakis, Emmanouil T\|Sandoval, Juan\|Moran, Sebastian\|Esteller, Manel\|Hansen, Torben F\|Lamy, Philippe\|Laurberg, Soren\|Orntoft, Torben F\|Andersen, Claus L
PMID:	23115050

673.
Journal:	Oncogene. 2013 Oct;32(40):4806-13.
Title:	Analysis of the combined action of miR-143 and miR-145 on oncogenic pathways in colorectal cancer cells reveals a coordinate program of gene repression.
Author:	Pagliuca, A\|Valvo, C\|Fabrizi, E\|di Martino, S\|Biffoni, M\|Runci, D\|Forte, S\|De Maria, R\|Ricci-Vitiani, L
PMID:	23128394

674.
Journal:	Clin Chem. 2013 Jan;59(1):252-60.
Title:	Heterogeneity of epidermal growth factor receptor status and mutations of KRAS/PIK3CA in circulating tumor cells of patients with colorectal cancer.
Author:	Gasch, Christin\|Bauernhofer, Thomas\|Pichler, Martin\|Langer-Freitag, Sabine\|Reeh, Matthias\|Seifert, Adrian M\|Mauermann, Oliver\|Izbicki, Jakob R\|Pantel, Klaus\|Riethdorf, Sabine
PMID:	23136247

675.
Journal:	Hum Pathol. 2013 May;44(5):829-36.
Title:	Epidermal growth factor receptor, phosphatidylinositol-3-kinase catalytic subunit/PTEN, and KRAS/NRAS/BRAF in primary resected esophageal adenocarcinomas: loss of PTEN is associated with worse clinical outcome.
Author:	Bettstetter, Marcus\|Berezowska, Sabina\|Keller, Gisela\|Walch, Axel\|Feuchtinger, Annette\|Slotta-Huspenina, Julia\|Feith, Marcus\|Drecoll, Enken\|Hofler, Heinz\|Langer, Rupert
PMID:	23158210

676.
Journal:	J Pathol. 2013 Feb;229(3):441-8.
Title:	Use of multivariate analysis to suggest a new molecular classification of colorectal cancer.
Author:	Domingo, Enric\|Ramamoorthy, Rajarajan\|Oukrif, Dahmane\|Rosmarin, Daniel\|Presz, Michal\|Wang, Haitao\|Pulker, Hannah\|Lockstone, Helen\|Hveem, Tarjei\|Cranston, Treena\|Danielsen, Havard\|Novelli, Marco\|Davidson, Brian\|Xu, Zheng-Zhou\|Molloy, Peter\|Johnstone, Elain
PMID:	23165447

677.
Journal:	Int J Clin Oncol. 2013 Dec;18(6):1042-8.
Title:	Prognostic relevance of KRAS and BRAF mutations in Japanese patients with colorectal cancer.
Author:	Nakanishi, Ryota\|Harada, Jun\|Tuul, Munkhbold\|Zhao, Yan\|Ando, Koji\|Saeki, Hiroshi\|Oki, Eiji\|Ohga, Takefumi\|Kitao, Hiroyuki\|Kakeji, Yoshihiro\|Maehara, Yoshihiko
PMID:	23188063

678.
Journal:	J Gastroenterol. 2013 Mar;48(3):287-302.
Title:	Serrated polyps of the large intestine: current understanding of diagnosis, pathogenesis, and clinical management.
Author:	Rosty, Christophe\|Hewett, David G\|Brown, Ian S\|Leggett, Barbara A\|Whitehall, Vicki L J
PMID:	23208018

679.
Journal:	Am J Surg Pathol. 2013 Mar;37(3):434-42.
Title:	Multiplicity and molecular heterogeneity of colorectal carcinomas in individuals with serrated polyposis.
Author:	Rosty, Christophe\|Walsh, Michael D\|Walters, Rhiannon J\|Clendenning, Mark\|Pearson, Sally-Ann\|Jenkins, Mark A\|Win, Aung Ko\|Hopper, John L\|Sweet, Kevin\|Frankel, Wendy L\|Aronson, Melyssa\|Gallinger, Steve\|Goldblatt, Jack\|Tucker, Kathy\|Greening, Sian\|Gattas, Mi
PMID:	23211288

680.
Journal:	Mol Cancer Res. 2013 Feb;11(2):109-21.
Title:	Knockdown of PAK4 or PAK1 inhibits the proliferation of mutant KRAS colon cancer cells independently of RAF/MEK/ERK and PI3K/AKT signaling.
Author:	Tabusa, Hana\|Brooks, Teresa\|Massey, Andrew J
PMID:	23233484

681.
Journal:	Biochem J. 2013 Mar 1;450(2):285-94.
Title:	The BH3 mimetic ABT-263 synergizes with the MEK1/2 inhibitor selumetinib/AZD6244 to promote BIM-dependent tumour cell death and inhibit acquired resistance.
Author:	Sale, Matthew J\|Cook, Simon J
PMID:	23234544

682.
Journal:	Crit Rev Oncol Hematol. 2013 Jul;87(1):55-68.
Title:	BRAF mutations in melanoma and colorectal cancer: a single oncogenic mutation with different tumour phenotypes and clinical implications.
Author:	Sclafani, F\|Gullo, G\|Sheahan, K\|Crown, J
PMID:	23246082

683.
Journal:	Clin Cancer Res. 2013 Feb 1;19(3):657-67.
Title:	Resistance to BRAF inhibition in BRAF-mutant colon cancer can be overcome with PI3K inhibition or demethylating agents.
Author:	Mao, Muling\|Tian, Feng\|Mariadason, John M\|Tsao, Chun C\|Lemos, Robert Jr\|Dayyani, Farshid\|Gopal, Y N Vashisht\|Jiang, Zhi-Qin\|Wistuba, Ignacio I\|Tang, Xi M\|Bornman, William G\|Bollag, Gideon\|Mills, Gordon B\|Powis, Garth\|Desai, Jayesh\|Gallick, Gary E\|Davies,
PMID:	23251002

684.
Journal:	Oncol Lett. 2013 Jan;5(1):249-254.
Title:	Comparison of KRAS/BRAF mutations between primary tumors and serum in colorectal cancer: Biological and clinical implications.
Author:	Pu, Xingxiang\|Pan, Zhizhong\|Huang, Ying\|Tian, Ying\|Guo, Hongqiang\|Wu, Lin\|He, Xuexing\|Chen, Xinggui\|Zhang, Shaodan\|Lin, Tongyu
PMID:	23255930

685.
Journal:	Ann Surg Oncol. 2013 Dec;20 Suppl 3:S485-91.
Title:	KRAS and BRAF mutations in 203 esophageal squamous cell carcinomas: pyrosequencing technology and literature review.
Author:	Shigaki, Hironobu\|Baba, Yoshifumi\|Watanabe, Masayuki\|Miyake, Keisuke\|Murata, Asuka\|Iwagami, Shiro\|Ishimoto, Takatsugu\|Iwatsuki, Masaaki\|Yoshida, Naoya\|Baba, Hideo
PMID:	23274581

686.
Journal:	Clin Genet. 2013 Dec;84(6):522-30.
Title:	A population-based study of hereditary non-polyposis colorectal cancer: evidence of pathologic and genetic heterogeneity.
Author:	Warden, G\|Harnett, D\|Green, J\|Wish, T\|Woods, M O\|Green, R\|Dicks, E\|Rahman, P\|Zhai, G\|Parfrey, P
PMID:	23278430

687.
Journal:	Expert Opin Biol Ther. 2013 Feb;13(2):241-55.
Title:	Optimizing treatment of metastatic colorectal cancer patients with anti-EGFR antibodies: overcoming the mechanisms of cancer cell resistance.
Author:	Troiani, Teresa\|Zappavigna, Silvia\|Martinelli, Erika\|Addeo, Santolo R\|Stiuso, Paola\|Ciardiello, Fortunato\|Caraglia, Michele
PMID:	23281932

688.
Journal:	Mol Cancer. 2013 Jan 3;12:1.
Title:	Analysis of colorectal cancers in British Bangladeshi identifies early onset, frequent mucinous histotype and a high prevalence of RBFOX1 deletion.
Author:	Sengupta, Neel\|Yau, Christopher\|Sakthianandeswaren, Anuratha\|Mouradov, Dmitri\|Gibbs, Peter\|Suraweera, Nirosha\|Cazier, Jean-Baptiste\|Polanco-Echeverry, Guadalupe\|Ghosh, Anil\|Thaha, Mohamed\|Ahmed, Shafi\|Feakins, Roger\|Propper, David\|Dorudi, Sina\|Sieber, Oli
PMID:	23286373

689.
Journal:	Genet Test Mol Biomarkers. 2013 Feb;17(2):135-9.
Title:	The proto-oncogene KRAS and BRAF profiles and some clinical characteristics in colorectal cancer in the Turkish population.
Author:	Ozen, Filiz\|Ozdemir, Semra\|Zemheri, Ebru\|Hacimuto, Gizem\|Silan, Fatma\|Ozdemir, Ozturk
PMID:	23297805

690.
Journal:	Cancer Res. 2013 Mar 15;73(6):1912-21.
Title:	Mixed lineage kinase MLK4 is activated in colorectal cancers where it synergistically cooperates with activated RAS signaling in driving tumorigenesis.
Author:	Martini, Miriam\|Russo, Mariangela\|Lamba, Simona\|Vitiello, Elisa\|Crowley, Emily Hannah\|Sassi, Francesco\|Romanelli, Davide\|Frattini, Milo\|Marchetti, Antonio\|Bardelli, Alberto
PMID:	23319808

691.
Journal:	Biosens Bioelectron. 2013 May 15;43:257-63.
Title:	Sensitive electrochemical analysis of BRAF V600E mutation based on an amplification-refractory mutation system coupled with multienzyme functionalized Fe3O4/Au nanoparticles.
Author:	Situ, Bo\|Cao, Nannan\|Li, Bo\|Liu, Qinlan\|Lin, Li\|Dai, Zong\|Zou, Xiaoyong\|Cai, Zhen\|Wang, Qian\|Yan, Xiaohui\|Zheng, Lei
PMID:	23321558

692.
Journal:	Clin Epigenetics. 2013 Jan 16;5(1):2.
Title:	BRAF mutation-specific promoter methylation of FOX genes in colorectal cancer.
Author:	van Roon, Eddy H\|Boot, Arnoud\|Dihal, Ashwin A\|Ernst, Robert F\|van Wezel, Tom\|Morreau, Hans\|Boer, Judith M
PMID:	23324568

693.
Journal:	Dis Markers. 2013;34(3):171-7.
Title:	Duplex reverse-hybridization assay for the simultaneous detection of KRAS/BRAF mutations in FFPE-extracted genomic DNA from colorectal cancer specimens.
Author:	Buxhofer-Ausch, Veronika\|Ausch, Christoph\|Zeillinger, Robert\|Oberkanins, Christian\|Dandachi, Nadia\|Reiner-Concin, Angelika\|Kriegshauser, Gernot
PMID:	23324583

694.
Journal:	PLoS One. 2013;8(1):e47902.
Title:	SATB1 expression is associated with biologic behavior in colorectal carcinoma in vitro and in vivo.
Author:	Zhang, Jie\|Zhang, Baogang\|Zhang, Xumei\|Sun, Yingui\|Wei, Xiaolong\|McNutt, Michael A\|Lu, Shijun\|Liu, Yuqing\|Zhang, Donghong\|Wang, Mingyu\|Lin, Zhijuan\|Niu, Na
PMID:	23326301

695.
Journal:	Histopathology. 2013 Feb;62(3):367-86.
Title:	The serrated pathway to colorectal carcinoma: current concepts and challenges.
Author:	Bettington, Mark\|Walker, Neal\|Clouston, Andrew\|Brown, Ian\|Leggett, Barbara\|Whitehall, Vicki
PMID:	23339363

696.
Journal:	Histol Histopathol. 2013 May;28(5):585-95.
Title:	Epigenetic alterations in colorectal cancer: the CpG island methylator phenotype.
Author:	Bae, Jeong Mo\|Kim, Jung Ho\|Kang, Gyeong Hoon
PMID:	23341177

697.
Journal:	J Nucl Med. 2013 Mar;54(3):424-30.
Title:	3'-Deoxy-3'-18F-fluorothymidine PET predicts response to (V600E)BRAF-targeted therapy in preclinical models of colorectal cancer.
Author:	McKinley, Eliot T\|Smith, R Adam\|Zhao, Ping\|Fu, Allie\|Saleh, Samir A\|Uddin, Md Imam\|Washington, M Kay\|Coffey, Robert J\|Manning, H Charles
PMID:	23341544

698.
Journal:	Aliment Pharmacol Ther. 2013 Mar;37(5):546-54.
Title:	Stool DNA testing for the detection of colorectal neoplasia in patients with inflammatory bowel disease.
Author:	Kisiel, J B\|Yab, T C\|Nazer Hussain, F T\|Taylor, W R\|Garrity-Park, M M\|Sandborn, W J\|Loftus, E V\|Wolff, B G\|Smyrk, T C\|Itzkowitz, S H\|Rubin, D T\|Zou, H\|Mahoney, D W\|Ahlquist, D A
PMID:	23347191

699.
Journal:	Mod Pathol. 2013 Jun;26(6):825-34.
Title:	Colorectal carcinomas with KRAS mutation are associated with distinctive morphological and molecular features.
Author:	Rosty, Christophe\|Young, Joanne P\|Walsh, Michael D\|Clendenning, Mark\|Walters, Rhiannon J\|Pearson, Sally\|Pavluk, Erika\|Nagler, Belinda\|Pakenas, David\|Jass, Jeremy R\|Jenkins, Mark A\|Win, Aung Ko\|Southey, Melissa C\|Parry, Susan\|Hopper, John L\|Giles, Graham G
PMID:	23348904

700.
Journal:	Eur J Gastroenterol Hepatol. 2013 Mar;25(3):319-26.
Title:	A correlation of the endoscopic characteristics of colonic laterally spreading tumours with genetic alterations.
Author:	Metz, Andrew J\|Bourke, Michael J\|Moss, Alan\|Dower, Ashraf\|Zarzour, Peter\|Hawkins, Nicholas J\|Ward, Robyn L\|Hesson, Luke B
PMID:	23354161

701.
Journal:	Int J Cancer. 2013 Aug 1;133(3):590-6.
Title:	Alternative splicing of BRAF transcripts and characterization of C-terminally truncated B-Raf isoforms in colorectal cancer.
Author:	Hirschi, Benjamin\|Kolligs, Frank T
PMID:	23354951

702.
Journal:	EPMA J. 2013 Jan 28;4(1):3.
Title:	Targeted therapies in colorectal cancer-an integrative view by PPPM.
Author:	Hagan, Suzanne\|Orr, Maria C M\|Doyle, Brendan
PMID:	23356214

703.
Journal:	Neoplasia. 2013 Jan;15(1):102-11.
Title:	Ibuprofen inhibits colitis-induced overexpression of tumor-related Rac1b.
Author:	Matos, Paulo\|Kotelevets, Larissa\|Goncalves, Vania\|Henriques, Andreai F A\|Zerbib, Philippe\|Moyer, Mary Pat\|Chastre, Eric\|Jordan, Peter
PMID:	23359345

704.
Journal:	Cancer Discov. 2013 May;3(5):520-33.
Title:	Relief of feedback inhibition of HER3 transcription by RAF and MEK inhibitors attenuates their antitumor effects in BRAF-mutant thyroid carcinomas.
Author:	Montero-Conde, Cristina\|Ruiz-Llorente, Sergio\|Dominguez, Jose M\|Knauf, Jeffrey A\|Viale, Agnes\|Sherman, Eric J\|Ryder, Mabel\|Ghossein, Ronald A\|Rosen, Neal\|Fagin, James A
PMID:	23365119

705.
Journal:	BMC Cancer. 2013 Feb 2;13:49.
Title:	Biomarkers of benefit from cetuximab-based therapy in metastatic colorectal cancer: interaction of EGFR ligand expression with RAS/RAF, PIK3CA genotypes.
Author:	Pentheroudakis, George\|Kotoula, Vassiliki\|De Roock, Wendy\|Kouvatseas, George\|Papakostas, Pavlos\|Makatsoris, Thomas\|Papamichael, Demetris\|Xanthakis, Ioannis\|Sgouros, Joseph\|Televantou, Despina\|Kafiri, Georgia\|Tsamandas, Athanassios C\|Razis, Evangelia\|Galan
PMID:	23374602

706.
Journal:	Clin Gastroenterol Hepatol. 2013 Jun;11(6):705-11; quiz e46.
Title:	Clinical subtypes and molecular characteristics of serrated polyposis syndrome.
Author:	Guarinos, Carla\|Sanchez-Fortun, Cristina\|Rodriguez-Soler, Maria\|Perez-Carbonell, Lucia\|Egoavil, Cecilia\|Juarez, Miriam\|Serradesanferm, Anna\|Bujanda, Luis\|Fernandez-Banares, Fernando\|Cubiella, Joaquin\|de-Castro, Luisa\|Guerra, Ana\|Aguirre, Elena\|Herreros-de
PMID:	23376323

707.
Journal:	J Clin Oncol. 2013 Apr 1;31(10):1336-40.
Title:	Implementation of universal microsatellite instability and immunohistochemistry screening for diagnosing lynch syndrome in a large academic medical center.
Author:	Heald, Brandie\|Plesec, Thomas\|Liu, Xiuli\|Pai, Rish\|Patil, Deepa\|Moline, Jessica\|Sharp, Richard R\|Burke, Carol A\|Kalady, Matthew F\|Church, James\|Eng, Charis
PMID:	23401454

708.
Journal:	Clin Cancer Res. 2013 May 1;19(9):2301-9.
Title:	Molecular pathways: mitogen-activated protein kinase pathway mutations and drug resistance.
Author:	Pritchard, Antonia L\|Hayward, Nicholas K
PMID:	23406774

709.
Journal:	Br J Cancer. 2013 Mar 5;108(4):771-4.
Title:	Docetaxel plus cetuximab as second-line treatment for docetaxel-refractory oesophagogastric cancer: the AGITG ATTAX2 trial.
Author:	Tebbutt, N C\|Parry, M M\|Zannino, D\|Strickland, A H\|Van Hazel, G A\|Pavlakis, N\|Ganju, V\|Mellor, D\|Dobrovic, A\|Gebski, V J
PMID:	23412099

710.
Journal:	Diagn Pathol. 2013 Feb 20;8:31.
Title:	Right-sided rhabdoid colorectal tumors might be related to the serrated pathway.
Author:	Pancione, Massimo\|Remo, Andrea\|Sabatino, Lina\|Zanella, Caterina\|Votino, Carolina\|Fucci, Alessandra\|Di Blasi, Arturo\|Lepore, Giovanni\|Daniele, Bruno\|Fenizia, Francesca\|Molinari, Enrico\|Normanno, Nicola\|Manfrin, Erminia\|Vendraminelli, Roberto\|Colantuoni, Vi
PMID:	23425390

711.
Journal:	Genet Med. 2013 Jul;15(7):517-27.
Title:	Recommendations from the EGAPP Working Group: can testing of tumor tissue for mutations in EGFR pathway downstream effector genes in patients with metastatic colorectal cancer improve health outcomes by guiding decisions regarding anti-EGFR therapy?
Author:
PMID:	23429431

712.
Journal:	BioDrugs. 2013 Jun;27(3):213-24.
Title:	Regorafenib for gastrointestinal malignancies : from preclinical data to clinical results of a novel multi-target inhibitor.
Author:	Aprile, Giuseppe\|Macerelli, Marianna\|Giuliani, Francesco
PMID:	23435872

713.
Journal:	BMC Gastroenterol. 2013 Feb 27;13:36.
Title:	Management of stage II colon cancer - the use of molecular biomarkers for adjuvant therapy decision.
Author:	Donada, Marisa\|Bonin, Serena\|Barbazza, Renzo\|Pettirosso, Daniel\|Stanta, Giorgio
PMID:	23446022

714.
Journal:	J Gastrointest Oncol. 2013 Mar;4(1):72-81.
Title:	The role of EGFR monoclonal antibodies (MoABs) cetuximab/panitumab, and BRAF inhibitors in BRAF mutated colorectal cancer.
Author:	Muhammad, Shan\|Jiang, Zheng\|Liu, Zheng\|Kaur, Kavanjit\|Wang, Xishan
PMID:	23451330

715.
Journal:	Int J Mol Sci. 2013 Mar 4;14(3):5170-81.
Title:	EGFR Expression and KRAS and BRAF Mutational Status in Intestinal-Type Sinonasal Adenocarcinoma.
Author:	Szablewski, Vanessa\|Solassol, Jerome\|Poizat, Flora\|Larrieux, Marion\|Crampette, Louis\|Mange, Alain\|Bascoul-Mollevi, Caroline\|Costes, Valerie
PMID:	23459231

716.
Journal:	Cancer Epidemiol Biomarkers Prev. 2013 May;22(5):917-26.
Title:	Family history of colorectal cancer in BRAF p.V600E-mutated colorectal cancer cases.
Author:	Buchanan, Daniel D\|Win, Aung K\|Walsh, Michael D\|Walters, Rhiannon J\|Clendenning, Mark\|Nagler, Belinda\|Pearson, Sally-Ann\|Macrae, Finlay A\|Parry, Susan\|Arnold, Julie\|Winship, Ingrid\|Giles, Graham G\|Lindor, Noralane M\|Potter, John D\|Hopper, John L\|Rosty, Ch
PMID:	23462926

717.
Journal:	Eur J Endocrinol. 2013 Apr 29;168(6):795-804.
Title:	RAC1b overexpression in papillary thyroid carcinoma: a role to unravel.
Author:	Silva, Ana Luisa\|Carmo, Francisca\|Bugalho, Maria Joao
PMID:	23482591

718.
Journal:	J Egypt Natl Canc Inst. 2013 Mar;25(1):37-41.
Title:	The KRAS StripAssay for detection of KRAS mutation in Egyptian patients with colorectal cancer (CRC): a pilot study.
Author:	Abd El Kader, Yasser\|Emera, Gamal\|Safwat, Ezzat\|Kassem, Heba A\|Kassem, Neemat M
PMID:	23499205

719.
Journal:	Biomed Res Int. 2013;2013:181384.
Title:	Downregulation of DLC-1 gene by promoter methylation during primary colorectal cancer progression.
Author:	Peng, Haixia\|Long, Feng\|Wu, Zhiyuan\|Chu, Yimin\|Li, Ji\|Kuai, Rong\|Zhang, Jing\|Kang, Zhihua\|Zhang, Xinju\|Guan, Ming
PMID:	23509688

720.
Journal:	Cancer Treat Rev. 2013 Dec;39(8):908-24.
Title:	Molecular markers to predict outcome to antiangiogenic therapies in colorectal cancer: current evidence and future perspectives.
Author:	Custodio, Ana\|Barriuso, Jorge\|de Castro, Javier\|Martinez-Marin, Virginia\|Moreno, Victor\|Rodriguez-Salas, Nuria\|Feliu, Jaime
PMID:	23510598

721.
Journal:	Br J Cancer. 2013 Apr 30;108(8):1757-64.
Title:	KRAS-mutation status in relation to colorectal cancer survival: the joint impact of correlated tumour markers.
Author:	Phipps, A I\|Buchanan, D D\|Makar, K W\|Win, A K\|Baron, J A\|Lindor, N M\|Potter, J D\|Newcomb, P A
PMID:	23511557

722.
Journal:	Br J Cancer. 2013 Apr 16;108(7):1495-501.
Title:	KRAS and BRAF mutations are rare and related to DNA mismatch repair deficiency in gastric cancer from the East and the West: results from a large international multicentre study.
Author:	van Grieken, N C T\|Aoyama, T\|Chambers, P A\|Bottomley, D\|Ward, L C\|Inam, I\|Buffart, T E\|Das, K\|Lim, T\|Pang, B\|Zhang, S L\|Tan, I B\|Carvalho, B\|Heideman, D A M\|Miyagi, Y\|Kameda, Y\|Arai, T\|Meijer, G A\|Tsuburaya, A\|Tan, P\|Yoshikawa, T\|Grabsch, H I
PMID:	23511561

723.
Journal:	Hum Mutat. 2013 Apr;34(4):636-43.
Title:	Genotyping by induced Forster Resonance Energy Transfer(iFRET) mechanism and simultaneous mutation scanning.
Author:	Masojc, Bartlomiej\|Gorski, Bohdan\|van de Wetering, Thierry\|Debniak, Tadeusz\|Cybulski, Cezary\|Jakubowska, Anna\|Medrek, Krzysztof\|Rudnicka, Helena\|Dwight, Zachary Lawrence\|Lubinski, Jan
PMID:	23520118

724.
Journal:	PLoS One. 2013;8(3):e58089.
Title:	Utilization of quantitative in vivo pharmacology approaches to assess combination effects of everolimus and irinotecan in mouse xenograft models of colorectal cancer.
Author:	Bradshaw-Pierce, Erica L\|Pitts, Todd M\|Kulikowski, Gillian\|Selby, Heather\|Merz, Andrea L\|Gustafson, Daniel L\|Serkova, Natalie J\|Eckhardt, S Gail\|Weekes, Colin D
PMID:	23520486

725.
Journal:	Klin Onkol. 2013;26(1):25-30.
Title:	[Molecular biological diagnostics of KRAS and BRAF mutations in patients with colorectal cancer - laboratory experience].
Author:	Robesova, B\|Bajerova, M\|Vasikova, A\|Ostrizkova, L\|Hausnerova, J\|Kyclova, J\|Pospisilova, S\|Mayer, J\|Dvorakova, D
PMID:	23528169

726.
Journal:	J Mol Diagn. 2013 May;15(3):299-311.
Title:	KRAS, BRAF, and TP53 deep sequencing for colorectal carcinoma patient diagnostics.
Author:	Rechsteiner, Markus\|von Teichman, Adriana\|Ruschoff, Jan H\|Fankhauser, Niklaus\|Pestalozzi, Bernhard\|Schraml, Peter\|Weber, Achim\|Wild, Peter\|Zimmermann, Dieter\|Moch, Holger
PMID:	23531339

727.
Journal:	Asian Pac J Cancer Prev. 2013;14(1):329-32.
Title:	Somatic mutations of K-ras and BRAF in Thai colorectal cancer and their prognostic value.
Author:	Chaiyapan, Welawee\|Duangpakdee, Pongsanae\|Boonpipattanapong, Teeranut\|Kanngern, Samornmas\|Sangkhathat, Surasak
PMID:	23534748

728.
Journal:	PLoS One. 2013;8(3):e59939.
Title:	A new microarray substrate for ultra-sensitive genotyping of KRAS and BRAF gene variants in colorectal cancer.
Author:	Galbiati, Silvia\|Damin, Francesco\|Pinzani, Pamela\|Mancini, Irene\|Vinci, Serena\|Chiari, Marcella\|Orlando, Claudio\|Cremonesi, Laura\|Ferrari, Maurizio
PMID:	23536897

729.
Journal:	J Clin Oncol. 2013 Jun 1;31(16):2016-23.
Title:	Associations between cigarette smoking status and colon cancer prognosis among participants in North Central Cancer Treatment Group Phase III Trial N0147.
Author:	Phipps, Amanda I\|Shi, Qian\|Newcomb, Polly A\|Nelson, Garth D\|Sargent, Daniel J\|Alberts, Steven R\|Limburg, Paul J
PMID:	23547084

730.
Journal:	BMC Cancer. 2013 Apr 1;13:169.
Title:	High resolution melting analysis of KRAS, BRAF and PIK3CA in KRAS exon 2 wild-type metastatic colorectal cancer.
Author:	Guedes, Joana G\|Veiga, Isabel\|Rocha, Patricia\|Pinto, Pedro\|Pinto, Carla\|Pinheiro, Manuela\|Peixoto, Ana\|Fragoso, Maria\|Raimundo, Ana\|Ferreira, Paula\|Machado, Manuela\|Sousa, Nuno\|Lopes, Paula\|Araujo, Antonio\|Macedo, Joana\|Alves, Fernando\|Coutinho, Camila\|He
PMID:	23548132

731.
Journal:	Clin Cancer Res. 2013 May 15;19(10):2688-98.
Title:	Concomitant BRAF and PI3K/mTOR blockade is required for effective treatment of BRAF(V600E) colorectal cancer.
Author:	Coffee, Erin M\|Faber, Anthony C\|Roper, Jatin\|Sinnamon, Mark J\|Goel, Gautam\|Keung, Lily\|Wang, Wei Vivian\|Vecchione, Loredana\|de Vriendt, Veerle\|Weinstein, Barbara J\|Bronson, Roderick T\|Tejpar, Sabine\|Xavier, Ramnik J\|Engelman, Jeffrey A\|Martin, Eric S\|Hung
PMID:	23549875

732.
Journal:	Int J Cancer. 2013 Oct 1;133(7):1624-30.
Title:	BRAF V600E-specific immunohistochemistry for the exclusion of Lynch syndrome in MSI-H colorectal cancer.
Author:	Capper, David\|Voigt, Anita\|Bozukova, Gergana\|Ahadova, Aysel\|Kickingereder, Philipp\|von Deimling, Andreas\|von Knebel Doeberitz, Magnus\|Kloor, Matthias
PMID:	23553055

733.
Journal:	PLoS One. 2013;8(3):e59064.
Title:	MLH1 promoter methylation frequency in colorectal cancer patients and related clinicopathological and molecular features.
Author:	Li, Xia\|Yao, Xiaoping\|Wang, Yibaina\|Hu, Fulan\|Wang, Fan\|Jiang, Liying\|Liu, Yupeng\|Wang, Da\|Sun, Guizhi\|Zhao, Yashuang
PMID:	23555617

734.
Journal:	J Cancer. 2013;4(4):320-2.
Title:	Rare Though Not Mutually Exclusive: A Report of Three Cases of Concomitant KRAS and BRAF Mutation and a Review of the Literature.
Author:	Sahin, Ibrahim Halil\|Kazmi, Syed M A\|Yorio, Jeffrey T\|Bhadkamkar, Nishin A\|Kee, Bryan K\|Garrett, Christopher R
PMID:	23569465

735.
Journal:	Eur J Hum Genet. 2013 Dec;21(12):1383-8.
Title:	Oncogenic mutations and microsatellite instability phenotype predict specific anatomical subsite in colorectal cancer patients.
Author:	Corso, Giovanni\|Pascale, Valeria\|Flauti, Giuseppe\|Ferrara, Francesco\|Marrelli, Daniele\|Roviello, Franco
PMID:	23572025

736.
Journal:	Br J Cancer. 2013 Apr 30;108(8):1750-6.
Title:	Van-Gogh-like 2 antagonises the canonical WNT pathway and is methylated in colorectal cancers.
Author:	Piazzi, G\|Selgrad, M\|Garcia, M\|Ceccarelli, C\|Fini, L\|Bianchi, P\|Laghi, L\|D'Angelo, L\|Paterini, P\|Malfertheiner, P\|Chieco, P\|Boland, C R\|Bazzoli, F\|Ricciardiello, L
PMID:	23579212

737.
Journal:	Am J Surg. 2013 May;205(5):608-12; discussion 612.
Title:	Stage III & IV colon and rectal cancers share a similar genetic profile: a review of the Oregon Colorectal Cancer Registry.
Author:	Gawlick, Ute\|Lu, Kim C\|Douthit, Miriam A\|Diggs, Brian S\|Schuff, Kathryn G\|Herzig, Daniel O\|Tsikitis, Vassiliki L
PMID:	23592171

738.
Journal:	Pathology. 2013 Jun;45(4):346-56.
Title:	Clinicopathological relevance of BRAF mutations in human cancer.
Author:	Pakneshan, Sahar\|Salajegheh, Ali\|Smith, Robert Anthony\|Lam, Alfred King-Yin
PMID:	23594689

739.
Journal:	Clin Adv Hematol Oncol. 2013 Apr;11(4):234-6.
Title:	The BRAF mutation in MLH1-deficient colorectal cancer.
Author:	Mahesh, Sameer A
PMID:	23604240

740.
Journal:	Mol Diagn Ther. 2013 Jun;17(3):193-203.
Title:	KRAS and BRAF mutation analysis in colorectal adenocarcinoma specimens with a low percentage of tumor cells.
Author:	Lewandowska, Marzena Anna\|Jozwicki, Wojciech\|Zurawski, Bogdan
PMID:	23606169

741.
Journal:	Cancer Manag Res. 2013 Apr 12;5:49-55.
Title:	Critical appraisal of the use of regorafenib in the management of colorectal cancer.
Author:	Festino, Lucia\|Fabozzi, Alessio\|Manzo, Anna\|Gambardella, Valentina\|Martinelli, Erika\|Troiani, Teresa\|De Vita, Ferdinando\|Orditura, Michele\|Ciardiello, Fortunato\|Morgillo, Floriana
PMID:	23610528

742.
Journal:	BMC Cancer. 2013 Apr 23;13:200.
Title:	Impact of KRAS, BRAF and PI3KCA mutations in rectal carcinomas treated with neoadjuvant radiochemotherapy and surgery.
Author:	Derbel, Olfa\|Wang, Qing\|Desseigne, Francoise\|Rivoire, Michel\|Meeus, Pierre\|Peyrat, Patrice\|Stella, Mattia\|Martel-Lafay, Isabelle\|Lemaistre, Anne-Isabelle\|de La Fouchardiere, Christelle
PMID:	23617638

743.
Journal:	Int J Cancer. 2013 Nov;133(9):2089-101.
Title:	Antitumor activity of pimasertib, a selective MEK 1/2 inhibitor, in combination with PI3K/mTOR inhibitors or with multi-targeted kinase inhibitors in pimasertib-resistant human lung and colorectal cancer cells.
Author:	Martinelli, Erika\|Troiani, Teresa\|D'Aiuto, Elena\|Morgillo, Floriana\|Vitagliano, Donata\|Capasso, Anna\|Costantino, Sarah\|Ciuffreda, Loreta Pia\|Merolla, Francesco\|Vecchione, Loredana\|De Vriendt, Veerle\|Tejpar, Sabine\|Nappi, Anna\|Sforza, Vincenzo\|Martini, Giu
PMID:	23629727

744.
Journal:	Br J Cancer. 2013 May 28;108(10):2088-96.
Title:	Geographic analysis of RKIP expression and its clinical relevance in colorectal cancer.
Author:	Koelzer, V H\|Karamitopoulou, E\|Dawson, H\|Kondi-Pafiti, A\|Zlobec, I\|Lugli, A
PMID:	23632477

745.
Journal:	Clin Cancer Res. 2013 Jun 15;19(12):3285-96.
Title:	PIK3CA and PTEN gene and exon mutation-specific clinicopathologic and molecular associations in colorectal cancer.
Author:	Day, Fiona L\|Jorissen, Robert N\|Lipton, Lara\|Mouradov, Dmitri\|Sakthianandeswaren, Anuratha\|Christie, Michael\|Li, Shan\|Tsui, Cary\|Tie, Jeannie\|Desai, Jayesh\|Xu, Zheng-Zhou\|Molloy, Peter\|Whitehall, Vicki\|Leggett, Barbara A\|Jones, Ian T\|McLaughlin, Stephen\|W
PMID:	23633456

746.
Journal:	Expert Opin Investig Drugs. 2013 Jun;22(6):739-49.
Title:	Phase I/II RAF kinase inhibitors in cancer therapy.
Author:	Turajlic, Samra\|Ali, Zohra\|Yousaf, Nadia\|Larkin, James
PMID:	23642225

747.
Journal:	Am J Surg Pathol. 2013 Aug;37(8):1192-200.
Title:	High-level microsatellite instability in appendiceal carcinomas.
Author:	Taggart, Melissa W\|Galbincea, John\|Mansfield, Paul F\|Fournier, Keith F\|Royal, Richard E\|Overman, Michael J\|Rashid, Asif\|Abraham, Susan C
PMID:	23648460

748.
Journal:	Genes Chromosomes Cancer. 2013 Aug;52(8):748-52.
Title:	BRAF V600E mutation detection by immunohistochemistry in colorectal carcinoma.
Author:	Affolter, Kajsa\|Samowitz, Wade\|Tripp, Sheryl\|Bronner, Mary P
PMID:	23650027

749.
Journal:	Clin Chem. 2013 Oct;59(10):1447-56.
Title:	Companion biomarkers: paving the pathway to personalized treatment for cancer.
Author:	Duffy, Michael J\|Crown, John
PMID:	23656699

750.
Journal:	Cancer. 2013 Aug 1;119(15):2765-70.
Title:	Mutation-specific antibody detects mutant BRAFV600E protein expression in human colon carcinomas.
Author:	Sinicrope, Frank A\|Smyrk, Thomas C\|Tougeron, David\|Thibodeau, Stephen N\|Singh, Shalini\|Muranyi, Andrea\|Shanmugam, Kandavel\|Grogan, Thomas M\|Alberts, Steven R\|Shi, Qian
PMID:	23657789

751.
Journal:	Br J Cancer. 2013 May 28;108(10):2153-63.
Title:	The prognostic role of KRAS, BRAF, PIK3CA and PTEN in colorectal cancer.
Author:	Eklof, V\|Wikberg, M L\|Edin, S\|Dahlin, A M\|Jonsson, B-A\|Oberg, A\|Rutegard, J\|Palmqvist, R
PMID:	23660947

752.
Journal:	Gastroenterology. 2013 Aug;145(2):348-56.e1-2.
Title:	Associations between colorectal cancer molecular markers and pathways with clinicopathologic features in older women.
Author:	Samadder, N Jewel\|Vierkant, Robert A\|Tillmans, Lori S\|Wang, Alice H\|Weisenberger, Daniel J\|Laird, Peter W\|Lynch, Charles F\|Anderson, Kristin E\|French, Amy J\|Haile, Robert W\|Potter, John D\|Slager, Susan L\|Smyrk, Thomas C\|Thibodeau, Stephen N\|Cerhan, James
PMID:	23665275

753.
Journal:	PLoS One. 2013 May 9;8(5):e62989.
Title:	A novel fully automated molecular diagnostic system (AMDS) for colorectal cancer mutation detection.
Author:	Kitano, Shiro\|Myers, Jamie\|Nakamura, Junko\|Yamane, Akio\|Yamashita, Mami\|Nakayama, Masato\|Tsukahara, Yusuke\|Ushida, Hiroshi\|Liu, Wanqing\|Ratain, Mark J\|Amano, Masahiko
PMID:	23671647

754.
Journal:	PLoS Med. 2013;10(5):e1001453.
Title:	Gene expression classification of colon cancer into molecular subtypes: characterization, validation, and prognostic value.
Author:	Marisa, Laetitia\|de Reynies, Aurelien\|Duval, Alex\|Selves, Janick\|Gaub, Marie Pierre\|Vescovo, Laure\|Etienne-Grimaldi, Marie-Christine\|Schiappa, Renaud\|Guenot, Dominique\|Ayadi, Mira\|Kirzin, Sylvain\|Chazal, Maurice\|Flejou, Jean-Francois\|Benchimol, Daniel\|Ber
PMID:	23700391

755.
Journal:	Lancet Oncol. 2013 Jul;14(8):749-59.
Title:	Panitumumab and irinotecan versus irinotecan alone for patients with KRAS wild-type, fluorouracil-resistant advanced colorectal cancer (PICCOLO): a prospectively stratified randomised trial.
Author:	Seymour, Matthew T\|Brown, Sarah R\|Middleton, Gary\|Maughan, Timothy\|Richman, Susan\|Gwyther, Stephen\|Lowe, Catherine\|Seligmann, Jennifer F\|Wadsley, Jonathan\|Maisey, Nick\|Chau, Ian\|Hill, Mark\|Dawson, Lesley\|Falk, Stephen\|O'Callaghan, Ann\|Benstead, Kim\|Chambe
PMID:	23725851

756.
Journal:	Int J Colorectal Dis. 2013 Dec;28(12):1637-42.
Title:	Descriptive profile of PIK3CA-mutated colorectal cancer in postmenopausal women.
Author:	Phipps, Amanda I\|Makar, Karen W\|Newcomb, Polly A
PMID:	23728594

757.
Journal:	Transl Oncol. 2013 Jun 1;6(3):319-28. Print 2013 Jun.
Title:	Circulating Cell-Free DNA from Colorectal Cancer Patients May Reveal High KRAS or BRAF Mutation Load.
Author:	Mouliere, Florent\|El Messaoudi, Safia\|Gongora, Celine\|Guedj, Anne-Sophie\|Robert, Bruno\|Del Rio, Maguy\|Molina, Franck\|Lamy, Pierre-Jean\|Lopez-Crapez, Evelyne\|Mathonnet, Muriel\|Ychou, Marc\|Pezet, Denis\|Thierry, Alain R
PMID:	23730412

758.
Journal:	J Gastrointest Oncol. 2013 Jun;4(2):182-92.
Title:	Signature of microsatellite instability, KRAS and BRAF gene mutations in German patients with locally advanced rectal adenocarcinoma before and after neoadjuvant 5-FU radiochemotherapy.
Author:	Demes, Melanie\|Scheil-Bertram, Stefanie\|Bartsch, Holger\|Fisseler-Eckhoff, Annette
PMID:	23730514

759.
Journal:	J Clin Oncol. 2013 Jul 10;31(20):2554-62.
Title:	Population-based molecular screening for Lynch syndrome: implications for personalized medicine.
Author:	Ward, Robyn L\|Hicks, Sian\|Hawkins, Nicholas J
PMID:	23733757

760.
Journal:	Clin Cancer Res. 2013 Aug 1;19(15):4104-13.
Title:	Somatic profiling of the epidermal growth factor receptor pathway in tumors from patients with advanced colorectal cancer treated with chemotherapy +/- cetuximab.
Author:	Smith, Christopher G\|Fisher, David\|Claes, Bart\|Maughan, Timothy S\|Idziaszczyk, Shelley\|Peuteman, Gilian\|Harris, Rebecca\|James, Michelle D\|Meade, Angela\|Jasani, Bharat\|Adams, Richard A\|Kenny, Sarah\|Kaplan, Richard\|Lambrechts, Diether\|Cheadle, Jeremy P
PMID:	23741067

761.
Journal:	Ann Surg Oncol. 2013 Dec;20 Suppl 3:S527-36.
Title:	Overexpression of hypoxia inducible factor-1 alpha is an independent risk factor for recurrence after curative resection of colorectal liver metastases.
Author:	Shimomura, Manabu\|Hinoi, Takao\|Kuroda, Shintaro\|Adachi, Tomohiro\|Kawaguchi, Yasuo\|Sasada, Tatsunari\|Takakura, Yuji\|Egi, Hiroyuki\|Okajima, Masazumi\|Tashiro, Hirotaka\|Nishizaka, Takashi\|Ohdan, Hideki
PMID:	23748663

762.
Journal:	Anticancer Res. 2013 Jun;33(6):2499-508.
Title:	Combination of CYP inhibitor with MEK/ERK inhibitor enhances the inhibitory effect on ERK in BRAF mutant colon cancer cells.
Author:	Lim, Sun Min\|Hwang, Jee Won\|Ahn, Joong Bae\|Bae, Soo Kyung\|Park, Chan Hee\|Kim, Ki-Yeol\|Rha, Sun Young\|Chung, Hyun Cheol\|Roh, Jae Kyung\|Shin, Sang Joon
PMID:	23749901

763.
Journal:	Mol Syst Biol. 2013;9:673.
Title:	Network quantification of EGFR signaling unveils potential for targeted combination therapy.
Author:	Klinger, Bertram\|Sieber, Anja\|Fritsche-Guenther, Raphaela\|Witzel, Franziska\|Berry, Leanne\|Schumacher, Dirk\|Yan, Yibing\|Durek, Pawel\|Merchant, Mark\|Schafer, Reinhold\|Sers, Christine\|Bluthgen, Nils
PMID:	23752269

764.
Journal:	Histopathology. 2013 Aug;63(2):187-93.
Title:	Immunohistochemistry using the BRAF V600E mutation-specific monoclonal antibody VE1 is not a useful surrogate for genotyping in colorectal adenocarcinoma.
Author:	Adackapara, Cheryl A\|Sholl, Lynette M\|Barletta, Justine A\|Hornick, Jason L
PMID:	23763264

765.
Journal:	Br J Cancer. 2013 Jul 23;109(2):408-15.
Title:	Methylation levels of LINE-1 in primary lesion and matched metastatic lesions of colorectal cancer.
Author:	Murata, A\|Baba, Y\|Watanabe, M\|Shigaki, H\|Miyake, K\|Ishimoto, T\|Iwatsuki, M\|Iwagami, S\|Sakamoto, Y\|Miyamoto, Y\|Yoshida, N\|Nosho, K\|Baba, H
PMID:	23764749

766.
Journal:	Rom J Morphol Embryol. 2013;54(2):241-5.
Title:	Molecular classification of colorectal cancer: a dream that can become a reality.
Author:	Gurzu, Simona\|Szentirmay, Z\|Jung, I
PMID:	23771065

767.
Journal:	Clin Colorectal Cancer. 2013 Sep;12(3):168-78.
Title:	Clinical utility of KRAS and BRAF mutations in a cohort of patients with colorectal neoplasms submitted for microsatellite instability testing.
Author:	Cushman-Vokoun, Allison M\|Stover, Daniel G\|Zhao, Zhiguo\|Koehler, Elizabeth A\|Berlin, Jordan D\|Vnencak-Jones, Cindy L
PMID:	23773459

768.
Journal:	PLoS One. 2013 Jun 13;8(6):e65479.
Title:	PIK3CA activating mutation in colorectal carcinoma: associations with molecular features and survival.
Author:	Rosty, Christophe\|Young, Joanne P\|Walsh, Michael D\|Clendenning, Mark\|Sanderson, Kristy\|Walters, Rhiannon J\|Parry, Susan\|Jenkins, Mark A\|Win, Aung Ko\|Southey, Melissa C\|Hopper, John L\|Giles, Graham G\|Williamson, Elizabeth J\|English, Dallas R\|Buchanan, Dani
PMID:	23785428

769.
Journal:	Am J Epidemiol. 2013 Jul 1;178(1):84-100.
Title:	A prospective study of duration of smoking cessation and colorectal cancer risk by epigenetics-related tumor classification.
Author:	Nishihara, Reiko\|Morikawa, Teppei\|Kuchiba, Aya\|Lochhead, Paul\|Yamauchi, Mai\|Liao, Xiaoyun\|Imamura, Yu\|Nosho, Katsuhiko\|Shima, Kaori\|Kawachi, Ichiro\|Qian, Zhi Rong\|Fuchs, Charles S\|Chan, Andrew T\|Giovannucci, Edward\|Ogino, Shuji
PMID:	23788674

770.
Journal:	Cancer Biol Ther. 2013 Aug;14(8):711-9.
Title:	FOLFIRI plus dulanermin (rhApo2L/TRAIL) in a patient with BRAF-mutant metastatic colon cancer.
Author:	Lim, Bora\|Scicchitano, Angelique\|Beachler, Cheryl\|Gusani, Niraj\|Sarwani, Nabeel\|Yang, Zhaohai\|Staveley-O'Carroll, Kevin\|Ashkenazi, Avi\|Portera, Chia\|El-Deiry, Wafik S
PMID:	23792567

771.
Journal:	Cancer Biol Ther. 2013 Aug;14(8):703-10.
Title:	Off-label use of cetuximab plus sorafenib and panitumumab plus regorafenib to personalize therapy for a patient with V600E BRAF-mutant metastatic colon cancer.
Author:	Al-Marrawi, Mhd Yaser\|Saroya, Bikramajit Singh\|Brennan, Matthew C\|Yang, Zhaohai\|Dykes, Thomas M\|El-Deiry, Wafik S
PMID:	23792568

772.
Journal:	Am J Surg Pathol. 2013 Oct;37(10):1592-602.
Title:	BRAFV600E immunohistochemistry facilitates universal screening of colorectal cancers for Lynch syndrome.
Author:	Toon, Christopher W\|Walsh, Michael D\|Chou, Angela\|Capper, David\|Clarkson, Adele\|Sioson, Loretta\|Clarke, Stephen\|Mead, Scott\|Walters, Rhiannon J\|Clendenning, Mark\|Rosty, Christophe\|Young, Joanne P\|Win, Aung Ko\|Hopper, John L\|Crook, Ashley\|von Deimling, And
PMID:	23797718

773.
Journal:	JAMA. 2013 Jun 26;309(24):2563-71.
Title:	Aspirin use and risk of colorectal cancer according to BRAF mutation status.
Author:	Nishihara, Reiko\|Lochhead, Paul\|Kuchiba, Aya\|Jung, Seungyoun\|Yamauchi, Mai\|Liao, Xiaoyun\|Imamura, Yu\|Qian, Zhi Rong\|Morikawa, Teppei\|Wang, Molin\|Spiegelman, Donna\|Cho, Eunyoung\|Giovannucci, Edward\|Fuchs, Charles S\|Chan, Andrew T\|Ogino, Shuji
PMID:	23800934

774.
Journal:	Crit Rev Oncol Hematol. 2013 Nov;88(2):272-83.
Title:	Molecular biomarkers of resistance to anti-EGFR treatment in metastatic colorectal cancer, from classical to innovation.
Author:	Giampieri, Riccardo\|Scartozzi, Mario\|Del Prete, Michela\|Maccaroni, Elena\|Bittoni, Alessandro\|Faloppi, Luca\|Bianconi, Maristella\|Cecchini, Luca\|Cascinu, Stefano
PMID:	23806981

775.
Journal:	Mod Pathol. 2013 Dec;26(12):1642-56.
Title:	Expression of MUC2, MUC5AC, MUC5B, and MUC6 mucins in colorectal cancers and their association with the CpG island methylator phenotype.
Author:	Walsh, Michael D\|Clendenning, Mark\|Williamson, Elizabeth\|Pearson, Sally-Ann\|Walters, Rhiannon J\|Nagler, Belinda\|Packenas, David\|Win, Aung K\|Hopper, John L\|Jenkins, Mark A\|Haydon, Andrew M\|Rosty, Christophe\|English, Dallas R\|Giles, Graham G\|McGuckin, Micha
PMID:	23807779

776.
Journal:	J Mol Diagn. 2013 Sep;15(5):652-60.
Title:	Similarities of molecular genetic changes in synchronous and metachronous colorectal cancers are limited and related to the cancers' proximities to each other.
Author:	Zauber, Peter\|Huang, Jiaying\|Sabbath-Solitare, Marlene\|Marotta, Stephen
PMID:	23810502

777.
Journal:	J Pathol. 2013 Sep;231(1):63-76.
Title:	Gene expression patterns unveil a new level of molecular heterogeneity in colorectal cancer.
Author:	Budinska, Eva\|Popovici, Vlad\|Tejpar, Sabine\|D'Ario, Giovanni\|Lapique, Nicolas\|Sikora, Katarzyna Otylia\|Di Narzo, Antonio Fabio\|Yan, Pu\|Hodgson, John Graeme\|Weinrich, Scott\|Bosman, Fred\|Roth, Arnaud\|Delorenzi, Mauro
PMID:	23836465

778.
Journal:	PLoS One. 2013 Jul 3;8(7):e67583.
Title:	Dabrafenib; preclinical characterization, increased efficacy when combined with trametinib, while BRAF/MEK tool combination reduced skin lesions.
Author:	King, Alastair J\|Arnone, Marc R\|Bleam, Maureen R\|Moss, Katherine G\|Yang, Jingsong\|Fedorowicz, Kelly E\|Smitheman, Kimberly N\|Erhardt, Joseph A\|Hughes-Earle, Angela\|Kane-Carson, Laurie S\|Sinnamon, Robert H\|Qi, Hongwei\|Rheault, Tara R\|Uehling, David E\|Laquer
PMID:	23844038

779.
Journal:	Cancer Cell. 2013 Jul 8;24(1):1-2.
Title:	BRAF: a driver of the serrated pathway in colon cancer.
Author:	Rustgi, Anil K
PMID:	23845435

780.
Journal:	Drugs. 2013 Jul;73(11):1245-54.
Title:	Trametinib: first global approval.
Author:	Wright, Cameron J M\|McCormack, Paul L
PMID:	23846731

781.
Journal:	Pathol Biol (Paris). 2013 Dec;61(6):273-6.
Title:	Distribution of KRAS and BRAF mutations in Moroccan patients with advanced colorectal cancer.
Author:	Marchoudi, N\|Amrani Hassani Joutei, H\|Jouali, F\|Fekkak, J\|Rhaissi, H
PMID:	23849768

782.
Journal:	Biomarkers. 2013 Sep;18(6):516-24.
Title:	DUSP 4 expression identifies a subset of colorectal cancer tumors that differ in MAPK activation, regardless of the genotype.
Author:	De Vriendt, Veerle\|De Roock, Wendy\|Di Narzo, Antonio Fabio\|Tian, Sun\|Biesmans, Bart\|Jacobs, Bart\|Budinska, Eva\|Sagaert, Xavier\|Rossi, Simona\|D'Ario, Giovanni\|Delorenzi, Mauro\|Simon, Iris\|Vecchione, Loredana\|Tejpar, Sabine
PMID:	23875912

783.
Journal:	Eur J Cancer. 2013 Oct;49(15):3076-82.
Title:	Feasibility of preemptive biomarker profiling for personalised early clinical drug development at a Comprehensive Cancer Center.
Author:	Wiesweg, Marcel\|Ting, Saskia\|Reis, Henning\|Worm, Karl\|Kasper, Stefan\|Tewes, Mitra\|Welt, Anja\|Richly, Heike\|Meiler, Johannes\|Bauer, Sebastian\|Hense, Jorg\|Gauler, Thomas C\|Kohler, Jens\|Eberhardt, Wilfried E\|Darwiche, Kaid\|Freitag, Lutz\|Stamatis, Georgios\|Br
PMID:	23876834

784.
Journal:	J Natl Cancer Inst. 2013 Aug 7;105(15):1075-7.
Title:	BRAF mutation and microsatellite instability status in colonic and rectal carcinoma: context really does matter.
Author:	Hamilton, Stanley R
PMID:	23878351

785.
Journal:	J Natl Cancer Inst. 2013 Aug 7;105(15):1151-6.
Title:	Microsatellite instability and BRAF mutation testing in colorectal cancer prognostication.
Author:	Lochhead, Paul\|Kuchiba, Aya\|Imamura, Yu\|Liao, Xiaoyun\|Yamauchi, Mai\|Nishihara, Reiko\|Qian, Zhi Rong\|Morikawa, Teppei\|Shen, Jeanne\|Meyerhardt, Jeffrey A\|Fuchs, Charles S\|Ogino, Shuji
PMID:	23878352

786.
Journal:	Am J Surg Pathol. 2013 Nov;37(11):1660-70.
Title:	Clinicopathologic features of synchronous colorectal carcinoma: A distinct subset arising from multiple sessile serrated adenomas and associated with high levels of microsatellite instability and favorable prognosis.
Author:	Hu, Huankai\|Chang, Daniel T\|Nikiforova, Marina N\|Kuan, Shih-Fan\|Pai, Reetesh K
PMID:	23887157

787.
Journal:	Expert Rev Mol Diagn. 2013 Jul;13(6):581-99.
Title:	Colorectal cancer diagnostics: biomarkers, cell-free DNA, circulating tumor cells and defining heterogeneous populations by single-cell analysis.
Author:	Kin, Cindy\|Kidess, Evelyn\|Poultsides, George A\|Visser, Brendan C\|Jeffrey, Stefanie S
PMID:	23895128

788.
Journal:	Am J Clin Pathol. 2013 Aug;140(2):177-83.
Title:	BRAF V600E mutation analysis simplifies the testing algorithm for Lynch syndrome.
Author:	Jin, Ming\|Hampel, Heather\|Zhou, Xiaoping\|Schunemann, Lisa\|Yearsley, Martha\|Frankel, Wendy L
PMID:	23897252

789.
Journal:	Anticancer Res. 2013 Aug;33(8):3053-9.
Title:	The growing galectin network in colon cancer and clinical relevance of cytoplasmic galectin-3 reactivity.
Author:	Dawson, Heather\|Andre, Sabine\|Karamitopoulou, Eva\|Zlobec, Inti\|Gabius, Hans-Joachim
PMID:	23898060

790.
Journal:	Br J Cancer. 2013 Aug 20;109(4):1004-12.
Title:	Prognostic implication of the CpG island methylator phenotype in colorectal cancers depends on tumour location.
Author:	Bae, J M\|Kim, J H\|Cho, N-Y\|Kim, T-Y\|Kang, G H
PMID:	23900220

791.
Journal:	Biomark Med. 2013 Aug;7(4):613-21.
Title:	Microsatellite instability affecting the T17 repeats in intron 8 of HSP110, as well as five mononucleotide repeats in patients with colorectal carcinoma.
Author:	Markovic, Srdjan\|Antic, Jadranka\|Dimitrijevic, Ivan\|Zogovic, Branimir\|Bojic, Daniela\|Svorcan, Petar\|Markovic, Velimir\|Krivokapic, Zoran
PMID:	23905898

792.
Journal:	PLoS One. 2013 Jul 26;8(7):e69604.
Title:	Validation of next generation sequencing technologies in comparison to current diagnostic gold standards for BRAF, EGFR and KRAS mutational analysis.
Author:	McCourt, Clare M\|McArt, Darragh G\|Mills, Ken\|Catherwood, Mark A\|Maxwell, Perry\|Waugh, David J\|Hamilton, Peter\|O'Sullivan, Joe M\|Salto-Tellez, Manuel
PMID:	23922754

793.
Journal:	Cancer Med. 2013 Jun;2(3):277-85.
Title:	Prognostic impact and the relevance of PTEN copy number alterations in patients with advanced colorectal cancer (CRC) receiving bevacizumab.
Author:	Price, Timothy J\|Hardingham, Jennifer E\|Lee, Chee K\|Townsend, Amanda R\|Wrin, Joseph W\|Wilson, Kate\|Weickhardt, Andrew\|Simes, Robert J\|Murone, Carmel\|Tebbutt, Niall C
PMID:	23930204

794.
Journal:	Cancer Med. 2013 Jun;2(3):296-304.
Title:	EGFR, KRAS, BRAF, and HER-2 molecular status in brain metastases from 77 NSCLC patients.
Author:	Villalva, Claire\|Duranton-Tanneur, Valerie\|Guilloteau, Karline\|Burel-Vandenbos, Fanny\|Wager, Michel\|Doyen, Jerome\|Levillain, Pierre Marie\|Fontaine, Denys\|Blons, Helene\|Pedeutour, Florence\|Karayan-Tapon, Lucie
PMID:	23930206

795.
Journal:	Virchows Arch. 2013 Oct;463(4):509-23.
Title:	Alterations in the EGFR pathway coincide in colorectal cancer and impact on prognosis.
Author:	Neumann, Jens\|Wehweck, Laura\|Maatz, Susanne\|Engel, Jutta\|Kirchner, Thomas\|Jung, Andreas
PMID:	23934607

796.
Journal:	Curr Gastroenterol Rep. 2013 Sep;15(9):342.
Title:	Serrated polyps: clinical implications and future directions.
Author:	Tadros, Michael\|Anderson, Joseph C
PMID:	23934652

797.
Journal:	Clin Chem. 2013 Dec;59(12):1722-31.
Title:	Multiplex picodroplet digital PCR to detect KRAS mutations in circulating DNA from the plasma of colorectal cancer patients.
Author:	Taly, Valerie\|Pekin, Deniz\|Benhaim, Leonor\|Kotsopoulos, Steve K\|Le Corre, Delphine\|Li, Xinyu\|Atochin, Ivan\|Link, Darren R\|Griffiths, Andrew D\|Pallier, Karine\|Blons, Helene\|Bouche, Olivier\|Landi, Bruno\|Hutchison, J Brian\|Laurent-Puig, Pierre
PMID:	23938455

798.
Journal:	Br J Cancer. 2013 Sep 17;109(6):1562-9.
Title:	Acute tumour response to the MEK1/2 inhibitor selumetinib (AZD6244, ARRY-142886) evaluated by non-invasive diffusion-weighted MRI.
Author:	Beloueche-Babari, M\|Jamin, Y\|Arunan, V\|Walker-Samuel, S\|Revill, M\|Smith, P D\|Halliday, J\|Waterton, J C\|Barjat, H\|Workman, P\|Leach, M O\|Robinson, S P
PMID:	23942066

799.
Journal:	Med Oncol. 2013;30(3):686.
Title:	Pattern of clinically relevant mutations in consecutive series of Russian colorectal cancer patients.
Author:	Yanus, Grigoriy A\|Belyaeva, Anna V\|Ivantsov, Alexandr O\|Kuligina, Ekatherina Sh\|Suspitsin, Evgeny N\|Mitiushkina, Natalia V\|Aleksakhina, Svetlana N\|Iyevleva, Aglaya G\|Zaitseva, Olga A\|Yatsuk, Olga S\|Gorodnova, Tatiana V\|Strelkova, Tatiana N\|Efremova, Sofia
PMID:	23943423

800.
Journal:	BMC Gastroenterol. 2013 Aug 19;13:129.
Title:	Morphological change of a laterally spreading rectal tumor over a short period.
Author:	Miyamoto, Hideaki\|Oono, Yasuhiro\|Fu, Kuang-l\|Ikematsu, Hiroaki\|Fujii, Satoshi\|Kojima, Takashi\|Yano, Tomonori\|Ochiai, Atsushi\|Sasaki, Yutaka\|Kaneko, Kazuhiro
PMID:	23957258

801.
Journal:	Cancer Epidemiol. 2013 Oct;37(5):556-61.
Title:	Distinct molecular features of colorectal cancer in Ghana.
Author:	Raskin, Leon\|Dakubo, Jonathan C B\|Palaski, Nicole\|Greenson, Joel K\|Gruber, Stephen B
PMID:	23962701

802.
Journal:	Virchows Arch. 2013 Nov;463(5):613-21.
Title:	BRAF mutation in sporadic colorectal cancer and Lynch syndrome.
Author:	Thiel, Alexandra\|Heinonen, Mira\|Kantonen, Jonas\|Gylling, Annette\|Lahtinen, Laura\|Korhonen, Mari\|Kytola, Soili\|Mecklin, Jukka-Pekka\|Orpana, Arto\|Peltomaki, Paivi\|Ristimaki, Ari
PMID:	23963522

803.
Journal:	Mol Med. 2013 Sep 10;19:286-93.
Title:	Influence of microsatellite instability and KRAS and BRAF mutations on lymph node harvest in stage I-III colon cancers.
Author:	Berg, Marianne\|Guriby, Marianne\|Nordgard, Oddmund\|Nedrebo, Bjorn S\|Ahlquist, Terje C\|Smaaland, Rune\|Oltedal, Satu\|Soreide, Jon Arne\|Korner, Hartwig\|Lothe, Ragnhild A\|Soreide, Kjetil
PMID:	23979710

804.
Journal:	Zhonghua Wei Chang Wai Ke Za Zhi. 2013 Aug;16(8):753-8.
Title:	[Association of epithermal growth factor receptor expression and its downstream gene mutation status with radiosensitivity of colorectal carcinoma cell lines in vitro].
Author:	Zuo, Zhi-gui\|Yu, Zhi-qi\|Gao, Xian-hua\|Wang, Hao\|Zhang, Chang\|Liu, Qi-zhi\|Han, Yi-fang\|Chen, Li-ping\|Zhang, Xiao-qing\|Fu, Chuan-gang
PMID:	23980047

805.
Journal:	World J Gastroenterol. 2013 Aug 28;19(32):5286-94.
Title:	Somatic molecular changes and histo-pathological features of colorectal cancer in Tunisia.
Author:	Aissi, Sana\|Buisine, Marie Pierre\|Zerimech, Farid\|Kourda, Nadia\|Moussa, Amel\|Manai, Mohamed\|Porchet, Nicole
PMID:	23983431

806.
Journal:	APMIS. 2013 Oct;121(10):954-66.
Title:	Molecular alterations of Ras-Raf-mitogen-activated protein kinase and phosphatidylinositol 3-kinase-Akt signaling pathways in colorectal cancers from a tertiary hospital at Kuala Lumpur, Malaysia.
Author:	Yip, Wai Kien\|Choo, Chee Wei\|Leong, Vincent Ching-Shian\|Leong, Pooi Pooi\|Jabar, Mohd Faisal\|Seow, Heng Fong
PMID:	23992303

807.
Journal:	J Gastrointest Oncol. 2013 Sep;4(3):285-98.
Title:	Integrating anti-EGFR therapies in metastatic colorectal cancer.
Author:	Haraldsdottir, Sigurdis\|Bekaii-Saab, Tanios
PMID:	23997940

808.
Journal:	J Gastrointest Oncol. 2013 Sep;4(3):308-18.
Title:	Markers of resistance to anti-EGFR therapy in colorectal cancer.
Author:	Shaib, Walid\|Mahajan, Reena\|El-Rayes, Bassel
PMID:	23997942

809.
Journal:	BMC Cancer. 2013 Sep 3;13:405.
Title:	Simultaneous identification of 36 mutations in KRAS codons 61 and 146, BRAF, NRAS, and PIK3CA in a single reaction by multiplex assay kit.
Author:	Bando, Hideaki\|Yoshino, Takayuki\|Shinozaki, Eiji\|Nishina, Tomohiro\|Yamazaki, Kentaro\|Yamaguchi, Kensei\|Yuki, Satoshi\|Kajiura, Shinya\|Fujii, Satoshi\|Yamanaka, Takeharu\|Tsuchihara, Katsuya\|Ohtsu, Atsushi
PMID:	24006859

810.
Journal:	J Clin Oncol. 2013 Oct 10;31(29):3664-72.
Title:	Prognostic impact of deficient DNA mismatch repair in patients with stage III colon cancer from a randomized trial of FOLFOX-based adjuvant chemotherapy.
Author:	Sinicrope, Frank A\|Mahoney, Michelle R\|Smyrk, Thomas C\|Thibodeau, Stephen N\|Warren, Robert S\|Bertagnolli, Monica M\|Nelson, Garth D\|Goldberg, Richard M\|Sargent, Daniel J\|Alberts, Steven R
PMID:	24019539

811.
Journal:	Biol Sex Differ. 2013 Sep 10;4(1):17.
Title:	Sex differences in the prognostic significance of KRAS codons 12 and 13, and BRAF mutations in colorectal cancer: a cohort study.
Author:	Wangefjord, Sakarias\|Sundstrom, Magnus\|Zendehrokh, Nooreldin\|Lindquist, Kajsa Ericson\|Nodin, Bjorn\|Jirstrom, Karin\|Eberhard, Jakob
PMID:	24020794

812.
Journal:	N Engl J Med. 2013 Sep 12;369(11):1023-34.
Title:	Panitumumab-FOLFOX4 treatment and RAS mutations in colorectal cancer.
Author:	Douillard, Jean-Yves\|Oliner, Kelly S\|Siena, Salvatore\|Tabernero, Josep\|Burkes, Ronald\|Barugel, Mario\|Humblet, Yves\|Bodoky, Gyorgy\|Cunningham, David\|Jassem, Jacek\|Rivera, Fernando\|Kocakova, Ilona\|Ruff, Paul\|Blasinska-Morawiec, Maria\|Smakal, Martin\|Canon, J
PMID:	24024839

813.
Journal:	Cancer Biol Ther. 2013 Dec;14(12):1098-103.
Title:	Single agent panitumumab in KRAS wild-type metastatic colorectal cancer patients following cetuximab-based regimens: Clinical outcome and biomarkers of efficacy.
Author:	Pietrantonio, Filippo\|Perrone, Federica\|Biondani, Pamela\|Maggi, Claudia\|Lampis, Andrea\|Bertan, Claudia\|Venturini, Filippo\|Tondulli, Luca\|Ferrari, Daris\|Ricci, Vincenzo\|Villa, Federica\|Barone, Gloria\|Bianco, Nadia\|Ghidini, Antonio\|Bossi, Ilaria\|Fanetti, Gi
PMID:	24025413

814.
Journal:	Am J Surg Pathol. 2013 Oct;37(10):1532-41.
Title:	Loss of CDX2/CK20 expression is associated with poorly differentiated carcinoma, the CpG island methylator phenotype, and adverse prognosis in microsatellite-unstable colorectal cancer.
Author:	Kim, Jung Ho\|Rhee, Ye-Young\|Bae, Jeong Mo\|Cho, Nam-Yun\|Kang, Gyeong Hoon
PMID:	24025523

815.
Journal:	Hum Pathol. 2013 Nov;44(11):2518-28.
Title:	Lynch syndrome-associated colorectal carcinoma: frequent involvement of the left colon and rectum and late-onset presentation supports a universal screening approach.
Author:	Hartman, Douglas J\|Brand, Randall E\|Hu, Huankai\|Bahary, Nathan\|Dudley, Beth\|Chiosea, Simon I\|Nikiforova, Marina N\|Pai, Reetesh K
PMID:	24034859

816.
Journal:	Am J Gastroenterol. 2013 Nov;108(11):1785-93.
Title:	Survival in stage II/III colorectal cancer is independently predicted by chromosomal and microsatellite instability, but not by specific driver mutations.
Author:	Mouradov, Dmitri\|Domingo, Enric\|Gibbs, Peter\|Jorissen, Robert N\|Li, Shan\|Soo, Pik Ying\|Lipton, Lara\|Desai, Jayesh\|Danielsen, Havard E\|Oukrif, Dahmane\|Novelli, Marco\|Yau, Christopher\|Holmes, Christopher C\|Jones, Ian T\|McLaughlin, Stephen\|Molloy, Peter\|Hawk
PMID:	24042191

817.
Journal:	Oncogenesis. 2013 Sep 16;2:e71.
Title:	Epigenetic and genetic features of 24 colon cancer cell lines.
Author:	Ahmed, D\|Eide, P W\|Eilertsen, I A\|Danielsen, S A\|Eknaes, M\|Hektoen, M\|Lind, G E\|Lothe, R A
PMID:	24042735

818.
Journal:	Neoplasma. 2013 Sep 20.
Title:	The role of tumor markers and biomarkers in colorectal cancer.
Author:	Lech, G\|Slotwinski, R\|Krasnodebski, I W
PMID:	24050544

819.
Journal:	Clin Ther. 2013 Sep;35(9):1282-303.
Title:	Epidermal growth factor receptor: pathway, therapies, and pipeline.
Author:	Goffin, John R\|Zbuk, Kevin
PMID:	24054705

820.
Journal:	PLoS One. 2013 Sep 16;8(9):e74950.
Title:	Colorectal cancers from distinct ancestral populations show variations in BRAF mutation frequency.
Author:	Hanna, Megan C\|Go, Christina\|Roden, Christine\|Jones, Robert T\|Pochanard, Panisa\|Javed, Ahmed Yasir\|Javed, Awais\|Mondal, Chandrani\|Palescandolo, Emanuele\|Van Hummelen, Paul\|Hatton, Charles\|Bass, Adam J\|Chun, Sung Min\|Na, Deuk Chae\|Kim, Tae-Im\|Jang, Se Jin\|
PMID:	24066160

821.
Journal:	Hum Pathol. 2013 Nov;44(11):2563-70.
Title:	Comparison of 2 monoclonal antibodies for immunohistochemical detection of BRAF V600E mutation in malignant melanoma, pulmonary carcinoma, gastrointestinal carcinoma, thyroid carcinoma, and gliomas.
Author:	Routhier, Caitlin Ann\|Mochel, Mark C\|Lynch, Kerry\|Dias-Santagata, Dora\|Louis, David N\|Hoang, Mai P
PMID:	24071017

822.
Journal:	BMC Cancer. 2013 Sep 27;13:439.
Title:	Context-dependent interpretation of the prognostic value of BRAF and KRAS mutations in colorectal cancer.
Author:	Popovici, Vlad\|Budinska, Eva\|Bosman, Fred T\|Tejpar, Sabine\|Roth, Arnaud D\|Delorenzi, Mauro
PMID:	24073892

823.
Journal:	Virchows Arch. 2013 Nov;463(5):623-31.
Title:	Ultra-deep sequencing confirms immunohistochemistry as a highly sensitive and specific method for detecting BRAF V600E mutations in colorectal carcinoma.
Author:	Rossle, Matthias\|Sigg, Michele\|Ruschoff, Jan H\|Wild, Peter J\|Moch, Holger\|Weber, Achim\|Rechsteiner, Markus P
PMID:	24085553

824.
Journal:	Mol Cancer Ther. 2013 Dec;12(12):2857-63.
Title:	Target-based therapeutic matching in early-phase clinical trials in patients with advanced colorectal cancer and PIK3CA mutations.
Author:	Ganesan, Prasanth\|Janku, Filip\|Naing, Aung\|Hong, David S\|Tsimberidou, Apostolia M\|Falchook, Gerald S\|Wheler, Jennifer J\|Piha-Paul, Sarina A\|Fu, Siqing\|Stepanek, Vanda M\|Lee, J Jack\|Luthra, Rajyalakshmi\|Overman, Michael J\|Kopetz, E Scott\|Wolff, Robert A\|Ku
PMID:	24092809

825.
Journal:	Oncol Rep. 2013 Dec;30(6):2909-16.
Title:	Molecular and clinical characteristics of MSH6 germline variants detected in colorectal cancer patients.
Author:	Terui, Hiroko\|Tachikawa, Tetsuhiko\|Kakuta, Miho\|Nishimura, Yoji\|Yatsuoka, Toshimasa\|Yamaguchi, Kensei\|Yura, Kei\|Akagi, Kiwamu
PMID:	24100870

826.
Journal:	Cancer. 2013 Dec 1;119(23):4137-44.
Title:	Incidence and prognostic impact of KRAS and BRAF mutation in patients undergoing liver surgery for colorectal metastases.
Author:	Karagkounis, Georgios\|Torbenson, Michael S\|Daniel, Hubert D\|Azad, Nilofer S\|Diaz, Luis A Jr\|Donehower, Ross C\|Hirose, Kenzo\|Ahuja, Nita\|Pawlik, Timothy M\|Choti, Michael A
PMID:	24104864

827.
Journal:	Mol Cancer Ther. 2013 Dec;12(12):2950-61.
Title:	BRAF V600E is a determinant of sensitivity to proteasome inhibitors.
Author:	Zecchin, Davide\|Boscaro, Valentina\|Medico, Enzo\|Barault, Ludovic\|Martini, Miriam\|Arena, Sabrina\|Cancelliere, Carlotta\|Bartolini, Alice\|Crowley, Emily H\|Bardelli, Alberto\|Gallicchio, Margherita\|Di Nicolantonio, Federica
PMID:	24107445

828.
Journal:	Colorectal Dis. 2013 Dec;15(12):e711-8.
Title:	BRAF mutation is associated with distinct clinicopathological characteristics in colorectal cancer: a systematic review and meta-analysis.
Author:	Clancy, C\|Burke, J P\|Kalady, M F\|Coffey, J C
PMID:	24112392

829.
Journal:	Front Oncol. 2013 Oct 11;3:265.
Title:	Loss of Cdx2 Expression in Primary Tumors and Lymph Node Metastases is Specific for Mismatch Repair-Deficiency in Colorectal Cancer.
Author:	Dawson, Heather\|Koelzer, Viktor H\|Lukesch, Anne C\|Mallaev, Makhmudbek\|Inderbitzin, Daniel\|Lugli, Alessandro\|Zlobec, Inti
PMID:	24130965

830.
Journal:	Oncology (Williston Park). 2013 Aug;27(8):746-54.
Title:	Use of molecular biomarkers to inform adjuvant therapy for colon cancer.
Author:	Mettu, Niharika B\|Hurwitz, Herbert\|Hsu, David S
PMID:	24133820

831.
Journal:	J Cancer Res Clin Oncol. 2013 Dec;139(12):2133-40.
Title:	Repositioning of the anthelmintic drug mebendazole for the treatment for colon cancer.
Author:	Nygren, Peter\|Fryknas, Marten\|Agerup, Bengt\|Larsson, Rolf
PMID:	24135855

832.
Journal:	Ann Oncol. 2013 Dec;24(12):3123-8.
Title:	HER2 in high-risk rectal cancer patients treated in EXPERT-C, a randomized phase II trial of neoadjuvant capecitabine and oxaliplatin (CAPOX) and chemoradiotherapy (CRT) with or without cetuximab.
Author:	Sclafani, F\|Roy, A\|Cunningham, D\|Wotherspoon, A\|Peckitt, C\|Gonzalez de Castro, D\|Tabernero, J\|Glimelius, B\|Cervantes, A\|Eltahir, Z\|Oates, J\|Chau, I
PMID:	24146218

833.
Journal:	BMC Med Genomics. 2013 Oct 23;6:43.
Title:	Association of candidate single nucleotide polymorphisms with somatic mutation of the epidermal growth factor receptor pathway.
Author:	Wormald, Samuel\|Milla, Liz\|O'Connor, Liam
PMID:	24152305

834.
Journal:	Medicina (B Aires). 2013;73(5):417-22.
Title:	[Clinical-pathological features and gene profile in colorectal cancer].
Author:	Perazzo, Florencia\|Piaggio, Fernando\|Krupitzki, Hugo\|Garcia, Alejandro\|Avagnina, Alejandra\|Elsner, Boris\|Denninghoff, Valeria
PMID:	24152396

835.
Journal:	Cancer Med. 2013 Aug;2(4):496-506.
Title:	PTEN expression is consistent in colorectal cancer primaries and metastases and associates with patient survival.
Author:	Atreya, Chloe E\|Sangale, Zaina\|Xu, Nafei\|Matli, Mary R\|Tikishvili, Eliso\|Welbourn, William\|Stone, Steven\|Shokat, Kevan M\|Warren, Robert S
PMID:	24156022

836.
Journal:	J Natl Compr Canc Netw. 2013 Sep;11 Suppl 4:S9-17.
Title:	Multigene assays in metastatic colorectal cancer.
Author:	Deeb, Kristin K\|Sram, Jakub P\|Gao, Hanlin\|Fakih, Marwan G
PMID:	24158971

837.
Journal:	Exp Mol Pathol. 2013 Dec;95(3):336-42.
Title:	B-Raf mutation: a key player in molecular biology of cancer.
Author:	Rahman, M A\|Salajegheh, A\|Smith, R A\|Lam, A K-Y
PMID:	24161954

838.
Journal:	J Clin Oncol. 2013 Dec 10;31(35):e448-51.
Title:	BRAF inhibitor-driven tumor proliferation in a KRAS-mutated colon carcinoma is not overcome by MEK1/2 inhibition.
Author:	Andrews, Miles C\|Behren, Andreas\|Chionh, Fiona\|Mariadason, John\|Vella, Laura J\|Do, Hongdo\|Dobrovic, Alexander\|Tebbutt, Niall\|Cebon, Jonathan
PMID:	24190114

839.
Journal:	Br J Cancer. 2013 Dec 10;109(12):3057-66.
Title:	Small bowel adenocarcinoma phenotyping, a clinicobiological prognostic study.
Author:	Aparicio, T\|Svrcek, M\|Zaanan, A\|Beohou, E\|Laforest, A\|Afchain, P\|Mitry, Emmanuel\|Taieb, J\|Di Fiore, F\|Gornet, J-M\|Thirot-Bidault, A\|Sobhani, I\|Malka, D\|Lecomte, T\|Locher, C\|Bonnetain, F\|Laurent-Puig, P
PMID:	24196786

840.
Journal:	J Natl Cancer Inst. 2013 Dec 4;105(23):1789-98.
Title:	Predictive and prognostic analysis of PIK3CA mutation in stage III colon cancer intergroup trial.
Author:	Ogino, Shuji\|Liao, Xiaoyun\|Imamura, Yu\|Yamauchi, Mai\|McCleary, Nadine J\|Ng, Kimmie\|Niedzwiecki, Donna\|Saltz, Leonard B\|Mayer, Robert J\|Whittom, Renaud\|Hantel, Alexander\|Benson, Al B 3rd\|Mowat, Rex B\|Spiegelman, Donna\|Goldberg, Richard M\|Bertagnolli, Monic
PMID:	24231454

841.
Journal:	PLoS One. 2013 Nov 7;8(11):e79898.
Title:	The homeobox gene MEIS1 is methylated in BRAF (p.V600E) mutated colon tumors.
Author:	Dihal, Ashwin A\|Boot, Arnoud\|van Roon, Eddy H\|Schrumpf, Melanie\|Farina-Sarasqueta, Arantza\|Fiocco, Marta\|Zeestraten, Eliane C M\|Kuppen, Peter J K\|Morreau, Hans\|van Wezel, Tom\|Boer, Judith M
PMID:	24244575

842.
Journal:	J Clin Oncol. 2013 Dec 20;31(36):4562-8.
Title:	Evaluating many treatments and biomarkers in oncology: a new design.
Author:	Kaplan, Richard\|Maughan, Timothy\|Crook, Angela\|Fisher, David\|Wilson, Richard\|Brown, Louise\|Parmar, Mahesh
PMID:	24248692

843.
Journal:	Clin Lab Med. 2013 Dec;33(4):835-59.
Title:	Molecular diagnostics in colorectal carcinoma.
Author:	Bhalla, Amarpreet\|Zulfiqar, Muhammad\|Weindel, Michael\|Shidham, Vinod B
PMID:	24267189

844.
Journal:	Cancer Manag Res. 2013 Nov 21;5:387-400.
Title:	Personalized treatment for advanced colorectal cancer: KRAS and beyond.
Author:	Patel, Gargi Surendra\|Karapetis, Christos S
PMID:	24294007

845.
Journal:	Front Oncol. 2013 Nov 15;3:281.
Title:	Toward a Molecular Classification of Colorectal Cancer: The Role of BRAF.
Author:	Thiel, Alexandra\|Ristimaki, Ari
PMID:	24298448

846.
Journal:	J Natl Compr Canc Netw. 2013 Dec 1;11(12):1585-94.
Title:	Sessile serrated polyps: an important route to colorectal cancer.
Author:	Kalady, Matthew F
PMID:	24335690

847.
Journal:	PLoS One. 2013 Dec 10;8(12):e81628.
Title:	Effectors of epidermal growth factor receptor pathway: the genetic profiling ofKRAS, BRAF, PIK3CA, NRAS mutations in colorectal cancer characteristics and personalized medicine.
Author:	Shen, Yinchen\|Wang, Jianfei\|Han, Xiaohong\|Yang, Hongying\|Wang, Shuai\|Lin, Dongmei\|Shi, Yuankai
PMID:	24339949

848.
Journal:	Onkologie. 2013;36(12):719-24.
Title:	RAS, BRAF, and TP53 gene mutations in Taiwanese colorectal cancer patients.
Author:	Chang, Ya-Sian\|Chang, Shun-Jen\|Yeh, Kun-Tu\|Lin, Tsai-Hsiu\|Chang, Jan-Gowth
PMID:	24356563

849.
Journal:	Cancer Biomark. 2013;13(5):359-66.
Title:	Somatic gene mutations in African Americans may predict worse outcomes in colorectal cancer.
Author:	Kang, Melissa\|Shen, Xiang J\|Kim, Sangmi\|Araujo-Perez, Felix\|Galanko, Joseph A\|Martin, Chris F\|Sandler, Robert S\|Keku, Temitope O
PMID:	24440976

850.
Journal:	Acta Chir Belg. 2013 Nov-Dec;113(6):385-90.
Title:	Mucinous differentiation in colorectal cancer: molecular, histological and clinical aspects.
Author:	Debunne, H\|Ceelen, W
PMID:	24494463

851.
Journal:	Mol Clin Oncol. 2013 Mar;1(2):291-296.
Title:	Analysis of the anatomic subsites, gender and age in unresectable advanced colorectal carcinomas in Tochigi, Japan suggests a shift in location towards the right side colon in elderly patients treated with cetuximab.
Author:	Tanaka, Toshio\|Ichikawa, Kazuhito\|Maruoka, Takashi\|Tomita, Shigeki\|Ueda, Hirofumi\|Yamaguchi, Takeshi\|Shida, Yosuke\|Kato, Hiroyuki\|Nagata, Hitoshi\|Kubota, Keiichi\|Akimoto, Naohiko\|Sakamoto, Chouitsu\|Imura, Johji\|Arita, Munefumi\|Tanaka, Hiroyuki\|Okamoto, Yo
PMID:	24649163

852.
Journal:	Gastroenterol Rep (Oxf). 2013 Jul;1(1):70-4.
Title:	BRAF mutation in multiple primary cancer with colorectal cancer and stomach cancer.
Author:	Lee, Seung-Hyun\|Ahn, Byung-Kwon\|Baek, Sung-Uhn\|Chang, Hee-Kyung
PMID:	24759670

853.
Journal:	Gastroenterol Rep (Oxf). 2013 Nov;1(3):166-83.
Title:	Biomarkers in precision therapy in colorectal cancer.
Author:	Reimers, Marlies S\|Zeestraten, Eliane C M\|Kuppen, Peter J K\|Liefers, Gerrit Jan\|van de Velde, Cornelis J H
PMID:	24759962

854.
Journal:	Gastroenterol Hepatol Bed Bench. 2013 Winter;6(1):6-13.
Title:	Clinical implications of BRAF mutation test in colorectal cancer.
Author:	Nazemalhosseini Mojarad, Ehsan\|Farahani, Roya Kishani\|Haghighi, Mahdi Montazer\|Aghdaei, Hamid Asadzadeh\|Kuppen, Peter Jk\|Zali, Mohammad Reza
PMID:	24834238

855.
Journal:	ACS Med Chem Lett. 2013 Feb 7;4(3):358-62.
Title:	Discovery of Dabrafenib: A Selective Inhibitor of Raf Kinases with Antitumor Activity against B-Raf-Driven Tumors.
Author:	Rheault, Tara R\|Stellwagen, John C\|Adjabeng, George M\|Hornberger, Keith R\|Petrov, Kimberly G\|Waterson, Alex G\|Dickerson, Scott H\|Mook, Robert A Jr\|Laquerre, Sylvie G\|King, Alastair J\|Rossanese, Olivia W\|Arnone, Marc R\|Smitheman, Kimberly N\|Kane-Carson, La
PMID:	24900673

856.
Journal:	Am J Clin Oncol. 2014 Apr;37(2):117-21.
Title:	A prospective pilot study of target-guided personalized chemotherapy with intensity-modulated radiotherapy in patients with early rectal cancer.
Author:	Cubillo, Antonio\|Hernando-Requejo, Ovidio\|Garcia-Garcia, Elena\|Rodriguez-Pascual, Jesus\|De Vicente, Emilio\|Morelli, Pia\|Rubio, Carmen\|Lopez-Rios, Fernando\|Muro, Avertano\|Lopez, Ulpiano\|Prados, Susana\|Quijano, Yolanda\|Hidalgo, Manuel
PMID:	23211222

857.
Journal:	PLoS One. 2013 Jun 3;8(6):e65117.
Title:	Prognostic significance of C-reactive protein polymorphism and KRAS/BRAF in synchronous liver metastasis from colorectal cancer.
Author:	Huang, Chi-Jung\|Teng, Hao-Wei\|Chien, Chih-Cheng\|Lin, Jen-Kou\|Yang, Shung-Haur
PMID:	23755178

858.
Journal:	Oncogene. 2014 Jun 5;33(23):2949-55.
Title:	Discovery of colorectal cancer PIK3CA mutation as potential predictive biomarker: power and promise of molecular pathological epidemiology.
Author:	Ogino, S\|Lochhead, P\|Giovannucci, E\|Meyerhardt, J A\|Fuchs, C S\|Chan, A T
PMID:	23792451

859.
Journal:	Int J Cancer. 2014 Feb 1;134(3):552-62.
Title:	Colorectal cancer intrinsic subtypes predict chemotherapy benefit, deficient mismatch repair and epithelial-to-mesenchymal transition.
Author:	Roepman, Paul\|Schlicker, Andreas\|Tabernero, Josep\|Majewski, Ian\|Tian, Sun\|Moreno, Victor\|Snel, Mireille H\|Chresta, Christine M\|Rosenberg, Robert\|Nitsche, Ulrich\|Macarulla, Teresa\|Capella, Gabriel\|Salazar, Ramon\|Orphanides, George\|Wessels, Lodewyk F A\|Bern
PMID:	23852808

860.
Journal:	Fam Cancer. 2014 Mar;13(1):1-12.
Title:	Endometrial tumour BRAF mutations and MLH1 promoter methylation as predictors of germline mismatch repair gene mutation status: a literature review.
Author:	Metcalf, Alexander M\|Spurdle, Amanda B
PMID:	23880961

861.
Journal:	Mod Pathol. 2014 Jan;27(1):135-44.
Title:	Improved molecular classification of serrated lesions of the colon by immunohistochemical detection of BRAF V600E.
Author:	Mesteri, Ildiko\|Bayer, Gunther\|Meyer, Jochen\|Capper, David\|Schoppmann, Sebastian F\|von Deimling, Andreas\|Birner, Peter
PMID:	23887306

862.
Journal:	Pharmacogenomics J. 2014 Jun;14(3):256-62.
Title:	Intergenic polymorphisms in the amphiregulin gene region as biomarkers in metastatic colorectal cancer patients treated with anti-EGFR plus irinotecan.
Author:	Sebio, A\|Paez, D\|Salazar, J\|Berenguer-Llergo, A\|Pare-Brunet, L\|Lasa, A\|Del Rio, E\|Tobena, M\|Martin-Richard, M\|Baiget, M\|Barnadas, A
PMID:	23959273

863.
Journal:	J Gastrointest Cancer. 2014 Mar;45(1):34-9.
Title:	Mutational and clinical predictors of pathologic complete response in the treatment of locally advanced rectal cancer.
Author:	Russo, Andrea L\|Ryan, David P\|Borger, Darrell R\|Wo, Jennifer Y\|Szymonifka, Jackie\|Liang, Wen-Yih\|Kwak, Eunice L\|Blaszkowsky, Lawrence S\|Clark, Jeffrey W\|Allen, Jill N\|Zhu, Andrew X\|Berger, David L\|Cusack, James C\|Mamon, Harvey J\|Haigis, Kevin M\|Hong, Theo
PMID:	24006244

864.
Journal:	Fam Cancer. 2014 Mar;13(1):109-19.
Title:	Cancer risk and overall survival in mismatch repair proficient hereditary non-polyposis colorectal cancer, Lynch syndrome and sporadic colorectal cancer.
Author:	Garre, Pilar\|Martin, Lorena\|Bando, Inmaculada\|Tosar, Alicia\|Llovet, Patricia\|Sanz, Julian\|Romero, Atocha\|de la Hoya, Miguel\|Diaz-Rubio, Eduardo\|Caldes, Trinidad
PMID:	24061861

865.
Journal:	Mod Pathol. 2014 May;27(5):644-50.
Title:	BRAFV600E immunohistochemistry in conjunction with mismatch repair status predicts survival in patients with colorectal cancer.
Author:	Toon, Christopher W\|Chou, Angela\|DeSilva, Keshani\|Chan, Joseph\|Patterson, Jillian\|Clarkson, Adele\|Sioson, Loretta\|Jankova, Lucy\|Gill, Anthony J
PMID:	24157612

866.
Journal:	Cancer Discov. 2014 Jan;4(1):42-52.
Title:	mTOR inhibition specifically sensitizes colorectal cancers with KRAS or BRAF mutations to BCL-2/BCL-XL inhibition by suppressing MCL-1.
Author:	Faber, Anthony C\|Coffee, Erin M\|Costa, Carlotta\|Dastur, Anahita\|Ebi, Hiromichi\|Hata, Aaron N\|Yeo, Alan T\|Edelman, Elena J\|Song, Youngchul\|Tam, Ah Ting\|Boisvert, Jessica L\|Milano, Randy J\|Roper, Jatin\|Kodack, David P\|Jain, Rakesh K\|Corcoran, Ryan B\|Rivera,
PMID:	24163374

867.
Journal:	Int J Cancer. 2014 May 15;134(10):2342-51.
Title:	Possible role of Cdx2 in the serrated pathway of colorectal cancer characterized by BRAF mutation, high-level CpG Island methylator phenotype and mismatch repair-deficiency.
Author:	Dawson, Heather\|Galvan, Jose A\|Helbling, Melina\|Muller, Dominique-Elisabeth\|Karamitopoulou, Eva\|Koelzer, Viktor H\|Economou, Mary\|Hammer, Caroline\|Lugli, Alessandro\|Zlobec, Inti
PMID:	24166180

868.
Journal:	J Mol Diagn. 2014 Jan;16(1):116-26.
Title:	Age at onset should be a major criterion for subclassification of colorectal cancer.
Author:	Perea, Jose\|Rueda, Daniel\|Canal, Alicia\|Rodriguez, Yolanda\|Alvaro, Edurne\|Osorio, Irene\|Alegre, Cristina\|Rivera, Barbara\|Martinez, Joaquin\|Benitez, Javier\|Urioste, Miguel
PMID:	24184227

869.
Journal:	Neoplasma. 2014;61(1):1-8.
Title:	The role of tumor markers and biomarkers in colorectal cancer.
Author:	Lech, G\|Slotwinski, R\|Krasnodebski, I W
PMID:	24195503

870.
Journal:	Clin Cancer Res. 2014 Feb 1;20(3):744-53.
Title:	PIK3CA, BRAF, and PTEN status and benefit from cetuximab in the treatment of advanced colorectal cancer--results from NCIC CTG/AGITG CO.17.
Author:	Karapetis, Christos S\|Jonker, Derek\|Daneshmand, Manijeh\|Hanson, Jennifer E\|O'Callaghan, Christopher J\|Marginean, Celia\|Zalcberg, John R\|Simes, John\|Moore, Malcolm J\|Tebbutt, Niall C\|Price, Timothy J\|Shapiro, Jeremy D\|Pavlakis, Nick\|Gibbs, Peter\|Van Hazel,
PMID:	24218517

871.
Journal:	Carcinogenesis. 2014 Apr;35(4):776-83.
Title:	Association of microRNA-31 with BRAF mutation, colorectal cancer survival and serrated pathway.
Author:	Nosho, Katsuhiko\|Igarashi, Hisayoshi\|Nojima, Masanori\|Ito, Miki\|Maruyama, Reo\|Yoshii, Shinji\|Naito, Takafumi\|Sukawa, Yasutaka\|Mikami, Masashi\|Sumioka, Wakana\|Yamamoto, Eiichiro\|Kurokawa, Sei\|Adachi, Yasushi\|Takahashi, Hiroaki\|Okuda, Hiroyuki\|Kusumi, Takay
PMID:	24242331

872.
Journal:	Tumour Biol. 2014 Apr;35(4):2983-8.
Title:	Overexpression of miR-145 increases the sensitivity of vemurafenib in drug-resistant colo205 cell line.
Author:	Peng, Wei\|Hu, Jian\|Zhu, Xiao-dong\|Liu, Xin\|Wang, Chen-chen\|Li, Wen-hua\|Chen, Zhi-yu
PMID:	24248543

873.
Journal:	Int J Cancer. 2014 Jun 15;134(12):2820-8.
Title:	KRAS mutations and CDKN2A promoter methylation show an interactive adverse effect on survival and predict recurrence of rectal cancer.
Author:	Kohonen-Corish, Maija R J\|Tseung, Jason\|Chan, Charles\|Currey, Nicola\|Dent, Owen F\|Clarke, Stephen\|Bokey, Les\|Chapuis, Pierre H
PMID:	24259266

874.
Journal:	Ann Surg Oncol. 2014 Mar;21(3):946-54.
Title:	EGFR, BRAF and KRAS status in patients undergoing pulmonary metastasectomy from primary colorectal carcinoma: a prospective follow-up study.
Author:	Schweiger, Thomas\|Hegedus, Balazs\|Nikolowsky, Christoph\|Hegedus, Zita\|Szirtes, Ildiko\|Mair, Roland\|Birner, Peter\|Dome, Balazs\|Lang, Gyorgy\|Klepetko, Walter\|Ankersmit, Hendrik Jan\|Hoetzenecker, Konrad
PMID:	24281417

875.
Journal:	Mol Cancer Res. 2014 Jan;12(1):111-8.
Title:	ROS1 and ALK fusions in colorectal cancer, with evidence of intratumoral heterogeneity for molecular drivers.
Author:	Aisner, Dara L\|Nguyen, Teresa T\|Paskulin, Diego D\|Le, Anh T\|Haney, Jerry\|Schulte, Nathan\|Chionh, Fiona\|Hardingham, Jenny\|Mariadason, John\|Tebbutt, Niall\|Doebele, Robert C\|Weickhardt, Andrew J\|Varella-Garcia, Marileila
PMID:	24296758

876.
Journal:	Int J Oncol. 2014 Feb;44(2):548-56.
Title:	PRDX1 and PRDX6 are repressed in papillary thyroid carcinomas via BRAF V600E-dependent and -independent mechanisms.
Author:	Nicolussi, Arianna\|D'Inzeo, Sonia\|Mincione, Gabriella\|Buffone, Amelia\|Di Marcantonio, Maria Carmela\|Cotellese, Roberto\|Cichella, Annadomenica\|Capalbo, Carlo\|Di Gioia, Cira\|Nardi, Francesco\|Giannini, Giuseppe\|Coppa, Anna
PMID:	24316730

877.
Journal:	Pharmacol Ther. 2014 May;142(2):176-82.
Title:	BRAF inhibitors in cancer therapy.
Author:	Hertzman Johansson, Carolina\|Egyhazi Brage, Suzanne
PMID:	24325952

878.
Journal:	Clin Cancer Res. 2014 Mar 1;20(5):1087-94.
Title:	Aspirin and colorectal cancer: back to the future.
Author:	Tougeron, David\|Sha, Dan\|Manthravadi, Sashidhar\|Sinicrope, Frank A
PMID:	24327271

879.
Journal:	Hum Mutat. 2014 Mar;35(3):329-40.
Title:	Tumor heterogeneity revealed by KRAS, BRAF, and PIK3CA pyrosequencing: KRAS and PIK3CA intratumor mutation profile differences and their therapeutic implications.
Author:	Kosmidou, Vivian\|Oikonomou, Eftychia\|Vlassi, Margarita\|Avlonitis, Spyros\|Katseli, Anastasia\|Tsipras, Iraklis\|Mourtzoukou, Despina\|Kontogeorgos, Georgios\|Zografos, Georgios\|Pintzas, Alexander
PMID:	24352906

880.
Journal:	Clin Gastroenterol Hepatol. 2014 Mar;12(3):377-81.
Title:	DNA testing and molecular screening for colon cancer.
Author:	Carethers, John M
PMID:	24355100

881.
Journal:	Ann Oncol. 2014 Feb;25(2):404-8.
Title:	Activity of temozolomide in patients with advanced chemorefractory colorectal cancer and MGMT promoter methylation.
Author:	Pietrantonio, F\|Perrone, F\|de Braud, F\|Castano, A\|Maggi, C\|Bossi, I\|Gevorgyan, A\|Biondani, P\|Pacifici, M\|Busico, A\|Gariboldi, M\|Festinese, F\|Tamborini, E\|Di Bartolomeo, M
PMID:	24379162

882.
Journal:	Cancer Res. 2014 Mar 1;74(5):1311-8.
Title:	Fusobacterium in colonic flora and molecular features of colorectal carcinoma.
Author:	Tahara, Tomomitsu\|Yamamoto, Eiichiro\|Suzuki, Hiromu\|Maruyama, Reo\|Chung, Woonbok\|Garriga, Judith\|Jelinek, Jaroslav\|Yamano, Hiro-o\|Sugai, Tamotsu\|An, Byonggu\|Shureiqi, Imad\|Toyota, Minoru\|Kondo, Yutaka\|Estecio, Marcos R H\|Issa, Jean-Pierre J
PMID:	24385213

883.
Journal:	Mol Biol Rep. 2014 Mar;41(3):1291-8.
Title:	Effect of BRAF V600E mutation on tumor response of anti-EGFR monoclonal antibodies for first-line metastatic colorectal cancer treatment: a meta-analysis of randomized studies.
Author:	Cui, Dandan\|Cao, Dan\|Yang, Yu\|Qiu, Meng\|Huang, Ying\|Yi, Cheng
PMID:	24390240

884.
Journal:	Br J Cancer. 2014 Mar 4;110(5):1228-35.
Title:	Molecular heterogeneity and prognostic implications of synchronous advanced colorectal neoplasia.
Author:	Malesci, A\|Basso, G\|Bianchi, P\|Fini, L\|Grizzi, F\|Celesti, G\|Di Caro, G\|Delconte, G\|Dattola, F\|Repici, A\|Roncalli, M\|Montorsi, M\|Laghi, L
PMID:	24434431

885.
Journal:	Curr Cancer Drug Targets. 2014;14(2):128-43.
Title:	BRAF inhibitor therapy for melanoma, thyroid and colorectal cancers: development of resistance and future prospects.
Author:	Rahman, Md Atiqur\|Salajegheh, Ali\|Smith, Robert Anthony\|Lam, Alfred King-yin
PMID:	24446739

886.
Journal:	Br J Cancer. 2014 Mar 4;110(5):1359-66.
Title:	Influence of pre-diagnostic cigarette smoking on colorectal cancer survival: overall and by tumour molecular phenotype.
Author:	Zhu, Y\|Yang, S R\|Wang, P P\|Savas, S\|Wish, T\|Zhao, J\|Green, R\|Woods, M\|Sun, Z\|Roebothan, B\|Squires, J\|Buehler, S\|Dicks, E\|Zhao, J\|Mclaughlin, J R\|Parfrey, P S\|Campbell, P T
PMID:	24448365

887.
Journal:	Int J Exp Pathol. 2014 Feb;95(1):16-23.
Title:	DNA content analysis of colorectal cancer defines a distinct 'microsatellite and chromosome stable' group but does not predict response to radiotherapy.
Author:	Fadhil, Wakkas\|Kindle, Karin\|Jackson, Darryl\|Zaitoun, Abed\|Lane, Nina\|Robins, Adrian\|Ilyas, Mohammad
PMID:	24456329

888.
Journal:	Digestion. 2014;89(1):18-23.
Title:	Biomarkers for predicting the efficacy of anti-epidermal growth factor receptor antibody in the treatment of colorectal cancer.
Author:	Okada, Yasuyuki\|Miyamoto, Hiroshi\|Goji, Takahiro\|Takayama, Tetsuji
PMID:	24458108

889.
Journal:	Int J Cancer. 2014 Sep 1;135(5):1085-91.
Title:	Population-based screening for Lynch syndrome in Western Australia.
Author:	Schofield, Lyn\|Grieu, Fabienne\|Amanuel, Benhur\|Carrello, Amerigo\|Spagnolo, Dominic\|Kiraly, Cathy\|Pachter, Nicholas\|Goldblatt, Jack\|Platell, Cameron\|Levitt, Michael\|Stewart, Colin\|Salama, Paul\|Ee, Hooi\|Raftopoulous, Spiro\|Katris, Paul\|Threlfall, Tim\|Edkins
PMID:	24474394

890.
Journal:	PLoS One. 2014 Jan 30;9(1):e87966.
Title:	GNAS mutations identify a set of right-sided, RAS mutant, villous colon cancers.
Author:	Fecteau, Ryan E\|Lutterbaugh, James\|Markowitz, Sanford D\|Willis, Joseph\|Guda, Kishore
PMID:	24498230

891.
Journal:	Cancer Chemother Pharmacol. 2014 Apr;73(4):749-57.
Title:	Overexpression of MET is a new predictive marker for anti-EGFR therapy in metastatic colorectal cancer with wild-type KRAS.
Author:	Kishiki, Tomokazu\|Ohnishi, Hiroaki\|Masaki, Tadahiko\|Ohtsuka, Kouki\|Ohkura, Yasuo\|Furuse, Jyunji\|Watanabe, Takashi\|Sugiyama, Masanori
PMID:	24500024

892.
Journal:	Cancer. 2014 May 15;120(10):1482-90.
Title:	Mutational analysis and clinical correlation of metastatic colorectal cancer.
Author:	Russo, Andrea L\|Borger, Darrell R\|Szymonifka, Jackie\|Ryan, David P\|Wo, Jennifer Y\|Blaszkowsky, Lawrence S\|Kwak, Eunice L\|Allen, Jill N\|Wadlow, Raymond C\|Zhu, Andrew X\|Murphy, Janet E\|Faris, Jason E\|Dias-Santagata, Dora\|Haigis, Kevin M\|Ellisen, Leif W\|Iafr
PMID:	24500602

893.
Journal:	PLoS One. 2014 Feb 4;9(2):e87456.
Title:	Immunohistochemistry for myc predicts survival in colorectal cancer.
Author:	Toon, Christopher W\|Chou, Angela\|Clarkson, Adele\|DeSilva, Keshani\|Houang, Michelle\|Chan, Joseph C Y\|Sioson, Loretta L\|Jankova, Lucy\|Gill, Anthony J
PMID:	24503701

894.
Journal:	Am J Surg Pathol. 2014 Jul;38(7):910-20.
Title:	SMARCB1 (INI1)-negative rhabdoid carcinomas of the gastrointestinal tract: clinicopathologic and molecular study of a highly aggressive variant with literature review.
Author:	Agaimy, Abbas\|Rau, Tilman T\|Hartmann, Arndt\|Stoehr, Robert
PMID:	24503755

895.
Journal:	Epigenetics. 2014 May;9(5):738-46.
Title:	CpG island methylator phenotype and its association with malignancy in sporadic duodenal adenomas.
Author:	Sun, Lifeng\|Guzzetta, Angela A\|Fu, Tao\|Chen, Jinming\|Jeschke, Jana\|Kwak, Ruby\|Vatapalli, Rajita\|Baylin, Stephen B\|Iacobuzio-Donahue, Christine A\|Wolfgang, Christopher L\|Ahuja, Nita
PMID:	24518818

896.
Journal:	Curr Oncol. 2014 Feb;21(1):e151-4.
Title:	Anticancer activity of combination targeted therapy using cetuximab plus vemurafenib for refractory BRAF (V600E)-mutant metastatic colorectal carcinoma.
Author:	Connolly, K\|Brungs, D\|Szeto, E\|Epstein, R J
PMID:	24523613

897.
Journal:	Hum Pathol. 2014 Mar;45(3):464-72.
Title:	Immunohistochemical detection of BRAF V600E mutant protein using the VE1 antibody in colorectal carcinoma is highly concordant with molecular testing but requires rigorous antibody optimization.
Author:	Kuan, Shih-Fan\|Navina, Sarah\|Cressman, Kristi L\|Pai, Reetesh K
PMID:	24529329

898.
Journal:	Br J Cancer. 2014 Mar 18;110(6):1606-13.
Title:	RAD21 cohesin overexpression is a prognostic and predictive marker exacerbating poor prognosis in KRAS mutant colorectal carcinomas.
Author:	Deb, S\|Xu, H\|Tuynman, J\|George, J\|Yan, Y\|Li, J\|Ward, R L\|Mortensen, N\|Hawkins, N J\|McKay, M J\|Ramsay, R G\|Fox, S B
PMID:	24548858

899.
Journal:	Sci Transl Med. 2014 Feb 19;6(224):224ra26.
Title:	Blockade of EGFR and MEK intercepts heterogeneous mechanisms of acquired resistance to anti-EGFR therapies in colorectal cancer.
Author:	Misale, Sandra\|Arena, Sabrina\|Lamba, Simona\|Siravegna, Giulia\|Lallo, Alice\|Hobor, Sebastijan\|Russo, Mariangela\|Buscarino, Michela\|Lazzari, Luca\|Sartore-Bianchi, Andrea\|Bencardino, Katia\|Amatu, Alessio\|Lauricella, Calogero\|Valtorta, Emanuele\|Siena, Salvato
PMID:	24553387

900.
Journal:	Pathol Res Pract. 2014 May;210(5):274-8.
Title:	EGFR, KRAS, BRAF-mutations and microsatellite instability are absent in goblet cell carcinoids of the appendix.
Author:	Dimmler, Arno\|Geddert, Helene\|Faller, Gerhard
PMID:	24560515

901.
Journal:	J Clin Pathol. 2014 Jun;67(6):491-8.
Title:	Prevalence and molecular characterisation of the sessile serrated adenoma in a subset of the Chinese population.
Author:	Qiu, Ye\|Fu, Xiangsheng\|Zhang, Wei\|Xu, Yong\|Xiao, Lanyue\|Chen, Xia\|Shi, Lei\|Zhou, Xian\|Xia, Guodong\|Peng, Yan\|Deng, Mingming
PMID:	24570042

902.
Journal:	Clin Cancer Res. 2014 Apr 15;20(8):2126-35.
Title:	A peptide-based positron emission tomography probe for in vivo detection of caspase activity in apoptotic cells.
Author:	Hight, Matthew R\|Cheung, Yiu-Yin\|Nickels, Michael L\|Dawson, Eric S\|Zhao, Ping\|Saleh, Samir\|Buck, Jason R\|Tang, Dewei\|Washington, M Kay\|Coffey, Robert J\|Manning, H Charles
PMID:	24573549

903.
Journal:	Eur J Cancer. 2014 May;50(8):1430-6.
Title:	RAS mutations and cetuximab in locally advanced rectal cancer: results of the EXPERT-C trial.
Author:	Sclafani, F\|Gonzalez, D\|Cunningham, D\|Hulkki Wilson, S\|Peckitt, C\|Giralt, J\|Glimelius, B\|Rosello Keranen, S\|Wotherspoon, A\|Brown, G\|Tait, D\|Oates, J\|Chau, I
PMID:	24582914

904.
Journal:	Eur J Gastroenterol Hepatol. 2014 May;26(5):570-3.
Title:	Molecular and immunohistochemical profile of a basaloid (cloacogenic) carcinoma of the sigmoid colon: possible predictive value for clinical outcomes.
Author:	Gurzu, Simona\|Szentirmay, Zoltan\|Bara, Tivadar\|Bara, Tivadar Jr\|Iurcsuk, Olga\|Jung, Ioan
PMID:	24584270

905.
Journal:	Ann Oncol. 2014 May;25(5):1032-8.
Title:	Multicenter retrospective analysis of metastatic colorectal cancer (CRC) with high-level microsatellite instability (MSI-H).
Author:	Goldstein, J\|Tran, B\|Ensor, J\|Gibbs, P\|Wong, H L\|Wong, S F\|Vilar, E\|Tie, J\|Broaddus, R\|Kopetz, S\|Desai, J\|Overman, M J
PMID:	24585723

906.
Journal:	J Med Chem. 2014 Mar 27;57(6):2692-703.
Title:	Identification and optimization of new dual inhibitors of B-Raf and epidermal growth factor receptor kinases for overcoming resistance against vemurafenib.
Author:	Cheng, Huimin\|Chang, Yu\|Zhang, Lianwen\|Luo, Jinfeng\|Tu, Zhengchao\|Lu, Xiaoyun\|Zhang, Qingwen\|Lu, Jibu\|Ren, Xiaomei\|Ding, Ke
PMID:	24588073

907.
Journal:	Int J Cancer. 2014 Oct 1;135(7):1586-95.
Title:	Methylation epigenotypes and genetic features in colorectal laterally spreading tumors.
Author:	Sakai, Eiji\|Ohata, Ken\|Chiba, Hideyuki\|Matsuhashi, Nobuyuki\|Doi, Noriteru\|Fukushima, Junichi\|Endo, Hiroki\|Takahashi, Hirokazu\|Tsuji, Shingo\|Yagi, Koichi\|Matsusaka, Keisuke\|Aburatani, Hiroyuki\|Nakajima, Atsushi\|Kaneda, Atsushi
PMID:	24590867

908.
Journal:	Exp Mol Pathol. 2014 Apr;96(2):257-60.
Title:	KRAS insertions in colorectal cancer: what do we know about unusual KRAS mutations?
Author:	de Macedo, Mariana Petaccia\|de Lima, Luiz Guilherme Cernaglia Aureliano\|Begnami, Maria Dirlei Ferreira de Souza\|de Melo, Fernanda Machado\|Andrade, Louise D Brot\|Lisboa, Bianca Cristina Garcia\|Soares, Luisa Martelli\|Soares, Fernando Augusto\|Carraro, Dirce
PMID:	24594115

909.
Journal:	PLoS One. 2014 Mar 3;9(3):e90607.
Title:	BRAFV600E mutation and its association with clinicopathological features of colorectal cancer: a systematic review and meta-analysis.
Author:	Chen, Dong\|Huang, Jun-Fu\|Liu, Kai\|Zhang, Li-Qun\|Yang, Zhao\|Chuai, Zheng-Ran\|Wang, Yun-Xia\|Shi, Da-Chuan\|Huang, Qing\|Fu, Wei-Ling
PMID:	24594804

910.
Journal:	J Cancer Res Clin Oncol. 2014 May;140(5):737-48.
Title:	EGFR gene gain and PTEN protein expression are favorable prognostic factors in patients with KRAS wild-type metastatic colorectal cancer treated with cetuximab.
Author:	Razis, Evangelia\|Pentheroudakis, George\|Rigakos, George\|Bobos, Mattheos\|Kouvatseas, George\|Tzaida, Olympia\|Makatsoris, Thomas\|Papakostas, Pavlos\|Bai, Maria\|Goussia, Anna\|Samantas, Epaminontas\|Papamichael, Demetrios\|Romanidou, Ourania\|Efstratiou, Ioannis\|T
PMID:	24595598

911.
Journal:	Nihon Rinsho. 2014 Jan;72(1):29-34.
Title:	[Perspective of personalized (precise) cancer therapy based on predictive biomarkers].
Author:	Osera, Shozo\|Yoshino, Takayuki
PMID:	24597345

912.
Journal:	Mod Pathol. 2014 Oct;27(10):1375-85.
Title:	Traditional serrated adenoma has two pathways of neoplastic progression that are distinct from the sessile serrated pathway of colorectal carcinogenesis.
Author:	Tsai, Jia-Huei\|Liau, Jau-Yu\|Lin, Yu-Lin\|Lin, Liang-In\|Cheng, Yi-Chen\|Cheng, Mei-Ling\|Jeng, Yung-Ming
PMID:	24603588

913.
Journal:	J Gastroenterol Hepatol. 2014 Jun;29(6):1192-9.
Title:	Distinct profile of HIF1alpha, PTCH, EphB2, or DNA repair protein expression and BRAF mutation in colorectal serrated adenoma.
Author:	Morimoto, Takashi\|Mitomi, Hiroyuki\|Saito, Tsuyoshi\|Takahashi, Michiko\|Murakami, Takashi\|Sakamoto, Naoto\|Yao, Takashi\|Watanabe, Sumio
PMID:	24612059

914.
Journal:	Cesk Patol. 2014 Jan;50(1):18-24.
Title:	[Lynch syndrome in the hands of pathologists].
Author:	Daum, Ondrej\|Benes, Zdenek\|Hadravsky, Ladislav\|Stehlik, Jan\|Cerna, Katerina\|Dusek, Martin\|Kokoskova, Bohuslava\|Michal, Michal
PMID:	24624982

915.
Journal:	Am J Surg Pathol. 2014 Apr;38(4):518-25.
Title:	Immunohistochemistry for annexin A10 can distinguish sporadic from Lynch syndrome-associated microsatellite-unstable colorectal carcinoma.
Author:	Pai, Reetesh K\|Shadrach, Bonnie L\|Carver, Paula\|Heald, Brandie\|Moline, Jessica\|Church, James\|Kalady, Matthew F\|Burke, Carol A\|Plesec, Thomas P\|Lai, Keith K\|Gonzalo, David H\|Pai, Rish K
PMID:	24625416

916.
Journal:	Oncol Rep. 2014 May;31(5):2115-22.
Title:	Cetuximab-mediated ADCC activity is correlated with the cell surface expression level of EGFR but not with the KRAS/BRAF mutational status in colorectal cancer.
Author:	Seo, Yuki\|Ishii, Yoshiyuki\|Ochiai, Hiroki\|Fukuda, Kazumasa\|Akimoto, Shingo\|Hayashida, Tetsu\|Okabayashi, Koji\|Tsuruta, Masashi\|Hasegawa, Hirotoshi\|Kitagawa, Yuko
PMID:	24626880

917.
Journal:	World J Gastroenterol. 2014 Mar 14;20(10):2634-40.
Title:	Serrated pathway in colorectal carcinogenesis.
Author:	Yamane, Leticia\|Scapulatempo-Neto, Cristovam\|Reis, Rui Manuel\|Guimaraes, Denise Peixoto
PMID:	24627599

918.
Journal:	Klin Onkol. 2014;27(1):38-44.
Title:	[Surgical treatment of metastases and its impact on prognosis in patients with metastatic colorectal carcinoma].
Author:	Sevcikova, K\|Usakova, V\|Bartosova, Z\|Sabol, M\|Ondrusova, M\|Ondrus, D\|Spanik, S
PMID:	24635436

919.
Journal:	PLoS One. 2014 Mar 18;9(3):e91033.
Title:	Multiple sporadic colorectal cancers display a unique methylation phenotype.
Author:	Gonzalo, Victoria\|Lozano, Juan Jose\|Alonso-Espinaco, Virginia\|Moreira, Leticia\|Munoz, Jenifer\|Pellise, Maria\|Castellvi-Bel, Sergi\|Bessa, Xavier\|Andreu, Montserrat\|Xicola, Rosa M\|Llor, Xavier\|Ruiz-Ponte, Clara\|Carracedo, Angel\|Jover, Rodrigo\|Castells, Anto
PMID:	24643221

920.
Journal:	PLoS One. 2014 Mar 20;9(3):e91739.
Title:	Microsatellite stable colorectal cancers stratified by the BRAF V600E mutation show distinct patterns of chromosomal instability.
Author:	Bond, Catherine E\|Nancarrow, Derek J\|Wockner, Leesa F\|Wallace, Leanne\|Montgomery, Grant W\|Leggett, Barbara A\|Whitehall, Vicki L J
PMID:	24651849

921.
Journal:	J Med Life. 2014 Mar 15;7(1):17-26. Epub 2014 Mar 25.
Title:	Translating clinical research of Molecular Biology into a personalized, multidisciplinary approach of colorectal cancer patients.
Author:	Strambu, V\|Garofil, D\|Pop, F\|Radu, P\|Bratucu, M\|Popa, F
PMID:	24653752

922.
Journal:	Int J Cancer. 2014 Nov 1;135(9):2215-22.
Title:	Changes in mutational status during third-line treatment for metastatic colorectal cancer--results of consecutive measurement of cell free DNA, KRAS and BRAF in the plasma.
Author:	Spindler, Karen-Lise Garm\|Pallisgaard, Niels\|Andersen, Rikke Fredslund\|Jakobsen, Anders
PMID:	24659028

923.
Journal:	World J Gastroenterol. 2014 Mar 21;20(11):2979-94.
Title:	Differential gene expression of chemokines in KRAS and BRAF mutated colorectal cell lines: role of cytokines.
Author:	Khan, Sajjad\|Cameron, Silke\|Blaschke, Martina\|Moriconi, Federico\|Naz, Naila\|Amanzada, Ahmad\|Ramadori, Giuliano\|Malik, Ihtzaz Ahmed
PMID:	24659889

924.
Journal:	BMC Gastroenterol. 2014 Mar 28;14:55.
Title:	DNA methylation subgroups and the CpG island methylator phenotype in gastric cancer: a comprehensive profiling approach.
Author:	Loh, Marie\|Liem, Natalia\|Vaithilingam, Aparna\|Lim, Pei Li\|Sapari, Nur Sabrina\|Elahi, Eiram\|Mok, Zuan Yu\|Cheng, Chee Leong\|Yan, Benedict\|Pang, Brendan\|Salto-Tellez, Manuel\|Yong, Wei Peng\|Iacopetta, Barry\|Soong, Richie
PMID:	24674026

925.
Journal:	PLoS Genet. 2014 Mar 27;10(3):e1004271.
Title:	Changes in colorectal carcinoma genomes under anti-EGFR therapy identified by whole-genome plasma DNA sequencing.
Author:	Mohan, Sumitra\|Heitzer, Ellen\|Ulz, Peter\|Lafer, Ingrid\|Lax, Sigurd\|Auer, Martina\|Pichler, Martin\|Gerger, Armin\|Eisner, Florian\|Hoefler, Gerald\|Bauernhofer, Thomas\|Geigl, Jochen B\|Speicher, Michael R
PMID:	24676216

926.
Journal:	PLoS One. 2014 Apr 1;9(4):e92147.
Title:	Gain of ALK gene copy number may predict lack of benefit from anti-EGFR treatment in patients with advanced colorectal cancer and RAS-RAF-PI3KCA wild-type status.
Author:	Pietrantonio, Filippo\|Maggi, Claudia\|Di Bartolomeo, Maria\|Facciorusso, Maria Grazia\|Perrone, Federica\|Testi, Adele\|Iacovelli, Roberto\|Miceli, Rosalba\|Bossi, Ilaria\|Leone, Giorgia\|Milione, Massimo\|Pelosi, Giuseppe\|de Braud, Filippo
PMID:	24691006

927.
Journal:	Ann Surg Oncol. 2014 Aug;21(8):2642-9.
Title:	The frequencies and clinical implications of mutations in 33 kinase-related genes in locally advanced rectal cancer: a pilot study.
Author:	Abdul-Jalil, Khairun I\|Sheehan, Katherine M\|Toomey, Sinead\|Schmid, Jasmin\|Prehn, Jochen\|O'Grady, Anthony\|Cummins, Robert\|O'Neill, Brian\|McNamara, Deborah A\|Deasy, Joseph\|Breathnach, Oscar\|Grogan, Liam\|Rogers, Ailin\|Doherty, Glen\|Winter, Des\|Ryan, John\|El-
PMID:	24700299

928.
Journal:	Lancet Oncol. 2014 May;15(6):631-9.
Title:	Intermittent chemotherapy plus either intermittent or continuous cetuximab for first-line treatment of patients with KRAS wild-type advanced colorectal cancer (COIN-B): a randomised phase 2 trial.
Author:	Wasan, Harpreet\|Meade, Angela M\|Adams, Richard\|Wilson, Richard\|Pugh, Cheryl\|Fisher, David\|Sydes, Benjamin\|Madi, Ayman\|Sizer, Bruce\|Lowdell, Charles\|Middleton, Gary\|Butler, Rachel\|Kaplan, Richard\|Maughan, Tim
PMID:	24703531

929.
Journal:	Dig Dis Sci. 2014 Sep;59(9):2255-63.
Title:	Genetic mechanisms in interval colon cancers.
Author:	Richter, James M\|Pino, Maria Simona\|Austin, Thomas R\|Campbell, Emily\|Szymonifka, Jackie\|Russo, Andrea L\|Hong, Theodore S\|Borger, Darrell\|Iafrate, A John\|Chung, Daniel C
PMID:	24705641

930.
Journal:	Virchows Arch. 2014 Jun;464(6):637-43.
Title:	VE1 immunohistochemistry accurately detects BRAF V600E mutations in colorectal carcinoma and can be utilized in the detection of poorly differentiated colorectal serrated adenocarcinoma.
Author:	Sajanti, Sara\|Sirnio, Paivi\|Vayrynen, Juha P\|Tuomisto, Anne\|Klintrup, Kai\|Makela, Jyrki\|Ristimaki, Ari\|Makinen, Markus J
PMID:	24722974

931.
Journal:	Int J Colorectal Dis. 2014 Jun;29(6):663-71.
Title:	Expression analysis of heat shock protein 90 (HSP90) and Her2 in colon carcinoma.
Author:	Drecoll, Enken\|Nitsche, Ulrich\|Bauer, Karina\|Berezowska, Sabina\|Slotta-Huspenina, Julia\|Rosenberg, Robert\|Langer, Rupert
PMID:	24733427

932.
Journal:	Methods Mol Biol. 2014;1160:189-214.
Title:	Clinical applications using digital PCR.
Author:	Bizouarn, Francisco
PMID:	24740231

933.
Journal:	Zhonghua Bing Li Xue Za Zhi. 2014 Feb;43(2):77-82.
Title:	[Comparative analysis of real-time quantitative PCR-Sanger sequencing method and TaqMan probe method for detection of KRAS/BRAF mutation in colorectal carcinomas].
Author:	Zhang, Xun\|Wang, Yuehua\|Gao, Ning\|Wang, Jinfen
PMID:	24742565

934.
Journal:	Mol Cancer Ther. 2014 Jun;13(6):1399-409.
Title:	Moguntinones--new selective inhibitors for the treatment of human colorectal cancer.
Author:	Maderer, Annett\|Plutizki, Stanislav\|Kramb, Jan-Peter\|Gopfert, Katrin\|Linnig, Monika\|Khillimberger, Katrin\|Ganser, Christopher\|Lauermann, Eva\|Dannhardt, Gerd\|Galle, Peter R\|Moehler, Markus
PMID:	24743703

935.
Journal:	Br J Cancer. 2014 Apr 29;110(9):2178-86.
Title:	A feasibility study testing four hypotheses with phase II outcomes in advanced colorectal cancer (MRC FOCUS3): a model for randomised controlled trials in the era of personalised medicine?
Author:	Maughan, T S\|Meade, A M\|Adams, R A\|Richman, S D\|Butler, R\|Fisher, D\|Wilson, R H\|Jasani, B\|Taylor, G R\|Williams, G T\|Sampson, J R\|Seymour, M T\|Nichols, L L\|Kenny, S L\|Nelson, A\|Sampson, C M\|Hodgkinson, E\|Bridgewater, J A\|Furniss, D L\|Roy, R\|Pope, M J\|Pope,
PMID:	24743706

936.
Journal:	Int J Cancer. 2014 Dec 1;135(11):2507-15.
Title:	MicroRNA-31 expression in relation to BRAF mutation, CpG island methylation and colorectal continuum in serrated lesions.
Author:	Ito, Miki\|Mitsuhashi, Kei\|Igarashi, Hisayoshi\|Nosho, Katsuhiko\|Naito, Takafumi\|Yoshii, Shinji\|Takahashi, Hiroaki\|Fujita, Masahiro\|Sukawa, Yasutaka\|Yamamoto, Eiichiro\|Takahashi, Taiga\|Adachi, Yasushi\|Nojima, Masanori\|Sasaki, Yasushi\|Tokino, Takashi\|Baba, Y
PMID:	24752710

937.
Journal:	Recent Results Cancer Res. 2014;201:215-25.
Title:	Vemurafenib.
Author:	Garbe, Claus\|Abusaif, Sail\|Eigentler, Thomas K
PMID:	24756795

938.
Journal:	Recent Results Cancer Res. 2014;201:241-8.
Title:	Trametinib.
Author:	Zeiser, Robert
PMID:	24756797

939.
Journal:	Rev Recent Clin Trials. 2014;9(1):8-12.
Title:	The Emerging Role of NRAS Mutations in Colorectal Cancer Patients Selected for Anti-EGFR Therapies.
Author:	Meriggi, Fausto\|Vermi, William\|Bertocchi, Paola\|Zaniboni, Alberto
PMID:	24758538

940.
Journal:	World J Gastroenterol. 2014 Apr 21;20(15):4230-43.
Title:	Molecular and prognostic heterogeneity of microsatellite-unstable colorectal cancer.
Author:	Kim, Jung Ho\|Kang, Gyeong Hoon
PMID:	24764661

941.
Journal:	World J Gastroenterol. 2014 Apr 21;20(15):4370-6.
Title:	Clinical meaning of BRAF mutation in Korean patients with advanced colorectal cancer.
Author:	Kim, Bun\|Park, Soo Jung\|Cheon, Jae Hee\|Kim, Tae Il\|Kim, Won Ho\|Hong, Sung Pil
PMID:	24764675

942.
Journal:	Oncol Lett. 2014 May;7(5):1532-1536.
Title:	KRAS and BRAF genotyping of synchronous colorectal carcinomas.
Author:	Giannini, Riccardo\|Lupi, Cristiana\|Loupakis, Fotios\|Servadio, Adele\|Cremolini, Chiara\|Sensi, Elisa\|Chiarugi, Massimo\|Antoniotti, Carlotta\|Basolo, Fulvio\|Falcone, Alfredo\|Fontanini, Gabriella
PMID:	24765171

943.
Journal:	Hum Pathol. 2014 Jul;45(7):1388-96.
Title:	Mismatch repair protein immunohistochemistry: a useful population screening strategy for Lynch syndrome.
Author:	Musulen, Eva\|Sanz, Carolina\|Munoz-Marmol, Ana Maria\|Ariza, Aurelio
PMID:	24768606

944.
Journal:	Anticancer Res. 2014 May;34(5):2061-8.
Title:	Molecular biomarkers and classification models in the evaluation of the prognosis of colorectal cancer.
Author:	Sideris, Michail\|Papagrigoriadis, Savvas
PMID:	24778007

945.
Journal:	Pathology. 2014 Jun;46(4):311-5.
Title:	BRAFV600E mutation analysis by immunohistochemistry in patients with thoracic metastases from colorectal cancer.
Author:	Ilie, Marius I\|Long-Mira, Elodie\|Hofman, Veronique\|Mouroux, Jerome\|Vignaud, Jean-Michel\|Gauchotte, Guillaume\|Begueret, Hugues\|Merlio, Jean-Philippe\|Emile, Jean-Francois\|Hebuterne, Xavier\|Hofman, Paul
PMID:	24798160

946.
Journal:	Future Oncol. 2014 Apr;10(5):713-23.
Title:	Pyrosequencing evaluation of low-frequency KRAS mutant alleles for EGF receptor therapy selection in metastatic colorectal carcinoma.
Author:	Natalicchio, Maria Iole\|Improta, Giuseppina\|Zupa, Angela\|Cursio, Olga Elisabetta\|Stampone, Emanuela\|Possidente, Luciana\|Teresa Gerardi, Assunta Maria\|Vita, Giulia\|Martini, Maurizio\|Cassano, Alessandra\|Piccoli, Claudia\|Romito, Sante\|Aieta, Michele\|Antonett
PMID:	24799053

947.
Journal:	Br J Cancer. 2014 May 27;110(11):2728-37.
Title:	Molecular patterns in deficient mismatch repair colorectal tumours: results from a French prospective multicentric biological and genetic study.
Author:	Etienne-Grimaldi, M-C\|Mahamat, A\|Chazal, M\|Laurent-Puig, P\|Olschwang, S\|Gaub, M-P\|Formento, J-L\|Formento, P\|Sudaka, A\|Boige, V\|Abderrahim-Ferkoune, A\|Benchimol, D\|Andre, T\|Houry, S\|Faucheron, J-L\|Letoublon, C\|Gilly, F-N\|Delpero, J-R\|Lasser, P\|Pradere, B\|P
PMID:	24800948

948.
Journal:	Appl Immunohistochem Mol Morphol. 2014 May-Jun;22(5):e8-e13.
Title:	The utility of BRAFV600E mutation-specific antibody for colon cancers with microsatellite instability.
Author:	Nolan, Stephanie\|Arnason, Thomas\|Drucker, Arik\|Huang, Weei-Yuarn
PMID:	24805134

949.
Journal:	Oncol Rep. 2014 Jul;32(1):50-6.
Title:	Clinicopathological characteristics and prognostic impact of colorectal cancers with NRAS mutations.
Author:	Ogura, Toshiro\|Kakuta, Miho\|Yatsuoka, Toshimasa\|Nishimura, Yoji\|Sakamoto, Hirohiko\|Yamaguchi, Kensei\|Tanabe, Minoru\|Tanaka, Yoichi\|Akagi, Kiwamu
PMID:	24806883

950.
Journal:	Clin Cancer Res. 2014 Jul 15;20(14):3775-86.
Title:	Primary and acquired resistance of colorectal cancer cells to anti-EGFR antibodies converge on MEK/ERK pathway activation and can be overcome by combined MEK/EGFR inhibition.
Author:	Troiani, Teresa\|Napolitano, Stefania\|Vitagliano, Donata\|Morgillo, Floriana\|Capasso, Anna\|Sforza, Vincenzo\|Nappi, Anna\|Ciardiello, Davide\|Ciardiello, Fortunato\|Martinelli, Erika
PMID:	24812410

951.
Journal:	Am J Surg Pathol. 2014 Sep;38(9):1235-41.
Title:	Detection of the BRAF V600E mutation in colon carcinoma: critical evaluation of the imunohistochemical approach.
Author:	Lasota, Jerzy\|Kowalik, Artur\|Wasag, Bartosz\|Wang, Zeng-Feng\|Felisiak-Golabek, Anna\|Coates, Tiffany\|Kopczynski, Janusz\|Gozdz, Stanislaw\|Miettinen, Markku
PMID:	24832158

952.
Journal:	Eur J Cancer. 2014 Jul;50(11):1973-81.
Title:	RAC1b overexpression correlates with poor prognosis in KRAS/BRAF WT metastatic colorectal cancer patients treated with first-line FOLFOX/XELOX chemotherapy.
Author:	Alonso-Espinaco, Virginia\|Cuatrecasas, Miriam\|Alonso, Vicente\|Escudero, Pilar\|Marmol, Maribel\|Horndler, Carlos\|Ortego, Javier\|Gallego, Rosa\|Codony-Servat, Jordi\|Garcia-Albeniz, Xabier\|Jares, Pedro\|Castells, Antoni\|Lozano, Juan Jose\|Rosell, Rafael\|Maurel,
PMID:	24833563

953.
Journal:	Oncol Rep. 2014 Jul;32(1):57-64.
Title:	Impact of genetic profiles on the efficacy of anti-EGFR antibodies in metastatic colorectal cancer with KRAS mutation.
Author:	Kishiki, Tomokazu\|Ohnishi, Hiroaki\|Masaki, Tadahiko\|Ohtsuka, Kouki\|Ohkura, Yasuo\|Furuse, Jyunji\|Sugiyama, Masanori\|Watanabe, Takashi
PMID:	24839940

954.
Journal:	Eur J Cancer. 2014 Jul;50(11):1964-72.
Title:	Comprehensive molecular characterisation of hereditary non-polyposis colorectal tumours with mismatch repair proficiency.
Author:	Bellido, Fernando\|Pineda, Marta\|Sanz-Pamplona, Rebeca\|Navarro, Matilde\|Nadal, Marga\|Lazaro, Conxi\|Blanco, Ignacio\|Moreno, Victor\|Capella, Gabriel\|Valle, Laura
PMID:	24841217

955.
Journal:	Ann Surg Oncol. 2014 Dec;21 Suppl 4:S680-6.
Title:	Clinical relevance of alterations in quantity and quality of plasma DNA in colorectal cancer patients: based on the mutation spectra detected in primary tumors.
Author:	Lin, Jen-Kou\|Lin, Pei-Ching\|Lin, Chien-Hsing\|Jiang, Jeng-Kai\|Yang, Shung-Haur\|Liang, Wen-Yi\|Chen, Wei-Shone\|Chang, Shih-Ching
PMID:	24841357

956.
Journal:	Expert Rev Mol Diagn. 2014 Jun;14(5):517-24.
Title:	A new generation of companion diagnostics: cobas BRAF, KRAS and EGFR mutation detection tests.
Author:	Angulo, Barbara\|Lopez-Rios, Fernando\|Gonzalez, David
PMID:	24844134

957.
Journal:	PLoS One. 2014 May 21;9(5):e98059.
Title:	Colorectal advanced neoplasms occur through dual carcinogenesis pathways in individuals with coexisting serrated polyps.
Author:	Yamada, Atsushi\|Minamiguchi, Sachiko\|Sakai, Yoshiharu\|Horimatsu, Takahiro\|Muto, Manabu\|Chiba, Tsutomu\|Boland, C Richard\|Goel, Ajay
PMID:	24849572

958.
Journal:	Surgery. 2014 Jun;155(6):1062-8.
Title:	Prognostic implication of mucinous histology in resected colorectal cancer liver metastases.
Author:	Lupinacci, Renato Micelli\|Mello, Evandro Sobroza\|Coelho, Fabricio Ferreira\|Kruger, Jaime Arthur Pirolla\|Perini, Marcos Vinicius\|Pinheiro, Rafael S\|Fonseca, Gilton Marques\|Cecconello, Ivan\|Herman, Paulo
PMID:	24856126

959.
Journal:	Am Soc Clin Oncol Educ Book. 2014:91-9.
Title:	The evolution of our molecular understanding of colorectal cancer: what we are doing now, what the future holds, and how tumor profiling is just the beginning.
Author:	Dienstmann, Rodrigo\|Salazar, Ramon\|Tabernero, Josep
PMID:	24857065

960.
Journal:	Gastroenterology. 2014 Sep;147(3):637-45.
Title:	CpG island methylator phenotype is associated with response to adjuvant irinotecan-based therapy for stage III colon cancer.
Author:	Shiovitz, Stacey\|Bertagnolli, Monica M\|Renfro, Lindsay A\|Nam, Eunmi\|Foster, Nathan R\|Dzieciatkowski, Slavomir\|Luo, Yanxin\|Lao, Victoria Valinluck\|Monnat, Raymond J Jr\|Emond, Mary J\|Maizels, Nancy\|Niedzwiecki, Donna\|Goldberg, Richard M\|Saltz, Leonard B\|Ven
PMID:	24859205

961.
Journal:	BMJ Open. 2014 May 23;4(5):e004652.
Title:	KRAS, NRAS and BRAF mutations in Greek and Romanian patients with colorectal cancer: a cohort study.
Author:	Negru, Serban\|Papadopoulou, Eirini\|Apessos, Angela\|Stanculeanu, Dana Lucia\|Ciuleanu, Eliade\|Volovat, Constantin\|Croitoru, Adina\|Kakolyris, Stylianos\|Aravantinos, Gerasimos\|Ziras, Nikolaos\|Athanasiadis, Elias\|Touroutoglou, Nikolaos\|Pavlidis, Nikolaos\|Kalof
PMID:	24859998

962.
Journal:	Rev Med Chil. 2014 Jan;142(1):55-60.
Title:	[BRAF gene mutation in wild-type KRAS patients with colorectal cancers].
Author:	Roa, Ivan\|Game, Anakaren\|Bizama, Carolina\|Schalper, Kurt
PMID:	24861115

963.
Journal:	Med Oncol. 2014 Jul;31(7):16.
Title:	Mutations of KRAS and PIK3CA as independent predictors of distant metastases in colorectal cancer.
Author:	Zhu, Kunli\|Yan, Hongjiang\|Wang, Renben\|Zhu, Hui\|Meng, Xiangjiao\|Xu, Xiaoqing\|Dou, Xue\|Chen, Dong
PMID:	24861917

964.
Journal:	Cancer Sci. 2014 Aug;105(8):1002-7.
Title:	Clinical impact of c-MET expression and genetic mutational status in colorectal cancer patients after liver resection.
Author:	Shoji, Hirokazu\|Yamada, Yasuhide\|Taniguchi, Hirokazu\|Nagashima, Kengo\|Okita, Natsuko\|Takashima, Atsuo\|Honma, Yoshitaka\|Iwasa, Satoru\|Kato, Ken\|Hamaguchi, Tetsuya\|Shimada, Yasuhiro
PMID:	24863535

965.
Journal:	Mol Cancer. 2014 May 31;13:135.
Title:	Analyses of clinicopathological, molecular, and prognostic associations of KRAS codon 61 and codon 146 mutations in colorectal cancer: cohort study and literature review.
Author:	Imamura, Yu\|Lochhead, Paul\|Yamauchi, Mai\|Kuchiba, Aya\|Qian, Zhi Rong\|Liao, Xiaoyun\|Nishihara, Reiko\|Jung, Seungyoun\|Wu, Kana\|Nosho, Katsuhiko\|Wang, Yaoyu E\|Peng, Shouyong\|Bass, Adam J\|Haigis, Kevin M\|Meyerhardt, Jeffrey A\|Chan, Andrew T\|Fuchs, Charles S\|O
PMID:	24885062

966.
Journal:	Mol Cancer. 2014 May 24;13:122.
Title:	Genetic targeting of B-RafV600E affects survival and proliferation and identifies selective agents against BRAF-mutant colorectal cancer cells.
Author:	Hirschi, Benjamin\|Gallmeier, Eike\|Ziesch, Andreas\|Marschall, Maximilian\|Kolligs, Frank T
PMID:	24885690

967.
Journal:	Hum Pathol. 2014 Aug;45(8):1704-12.
Title:	BRAF-mutated microsatellite stable colorectal carcinoma: an aggressive adenocarcinoma with reduced CDX2 and increased cytokeratin 7 immunohistochemical expression.
Author:	Landau, Michael S\|Kuan, Shih-Fan\|Chiosea, Simon\|Pai, Reetesh K
PMID:	24908142

968.
Journal:	Virchows Arch. 2014 Aug;465(2):155-63.
Title:	Invasion pattern and histologic features of tumor aggressiveness correlate with MMR protein expression, but are independent of activating KRAS and BRAF mutations in CRC.
Author:	Steinestel, Konrad\|Lennerz, Jochen K\|Eder, Stefan\|Kraft, Klaus\|Arndt, Annette
PMID:	24915895

969.
Journal:	PLoS One. 2014 Jun 11;9(2):e98964.
Title:	Associations of anthropometric factors with KRAS and BRAF mutation status of primary colorectal cancer in men and women: a cohort study.
Author:	Brandstedt, Jenny\|Wangefjord, Sakarias\|Nodin, Bjorn\|Eberhard, Jakob\|Sundstrom, Magnus\|Manjer, Jonas\|Jirstrom, Karin
PMID:	24918610

970.
Journal:	Cancer Epidemiol Biomarkers Prev. 2014 Aug;23(8):1628-37.
Title:	Predicted 25(OH)D score and colorectal cancer risk according to vitamin D receptor expression.
Author:	Jung, Seungyoun\|Qian, Zhi Rong\|Yamauchi, Mai\|Bertrand, Kimberly A\|Fitzgerald, Kathryn C\|Inamura, Kentaro\|Kim, Sun A\|Mima, Kosuke\|Sukawa, Yasutaka\|Zhang, Xuehong\|Wang, Molin\|Smith-Warner, Stephanie A\|Wu, Kana\|Fuchs, Charles S\|Chan, Andrew T\|Giovannucci, Ed
PMID:	24920642

971.
Journal:	Am J Surg Pathol. 2014 Oct;38(10):1418-28.
Title:	BRAF V600E immunohistochemistry is reliable in primary and metastatic colorectal carcinoma regardless of treatment status and shows high intratumoral homogeneity.
Author:	Bledsoe, Jacob R\|Kamionek, Michal\|Mino-Kenudson, Mari
PMID:	24921639

972.
Journal:	Hum Pathol. 2014 Aug;45(8):1697-703.
Title:	Loss of ARID1A expression in colorectal carcinoma is strongly associated with mismatch repair deficiency.
Author:	Chou, Angela\|Toon, Christopher W\|Clarkson, Adele\|Sioson, Loretta\|Houang, Michelle\|Watson, Nicole\|DeSilva, Keshani\|Gill, Anthony J
PMID:	24925223

973.
Journal:	J Natl Cancer Inst. 2014 Jun 12;106(7). pii: dju106.
Title:	Patient and tumor characteristics and BRAF and KRAS mutations in colon cancer, NCCTG/Alliance N0147.
Author:	Gonsalves, Wilson I\|Mahoney, Michelle R\|Sargent, Daniel J\|Nelson, Garth D\|Alberts, Steven R\|Sinicrope, Frank A\|Goldberg, Richard M\|Limburg, Paul J\|Thibodeau, Stephen N\|Grothey, Axel\|Hubbard, Joleen M\|Chan, Emily\|Nair, Suresh\|Berenberg, Jeffrey L\|McWilliam
PMID:	24925349

974.
Journal:	Clin Cancer Res. 2014 Jun 15;20(12):3261-71.
Title:	CHFR promoter methylation indicates poor prognosis in stage II microsatellite stable colorectal cancer.
Author:	Cleven, Arjen H G\|Derks, Sarah\|Draht, Muriel X G\|Smits, Kim M\|Melotte, Veerle\|Van Neste, Leander\|Tournier, Benjamin\|Jooste, Valerie\|Chapusot, Caroline\|Weijenberg, Matty P\|Herman, James G\|de Bruine, Adriaan P\|van Engeland, Manon
PMID:	24928946

975.
Journal:	Oncol Lett. 2014 Jun;7(6):1761-1766.
Title:	'Druggable' alterations detected by Ion Torrent in metastatic colorectal cancer patients.
Author:	Fang, Weijia\|Radovich, Milan\|Zheng, Yulong\|Fu, Cai-Yun\|Zhao, Peng\|Mao, Chengyu\|Zheng, Yi\|Zheng, Shusen
PMID:	24932229

976.
Journal:	Am J Gastroenterol. 2014 Aug;109(8):1205-14.
Title:	Progress and opportunities in molecular pathological epidemiology of colorectal premalignant lesions.
Author:	Lochhead, Paul\|Chan, Andrew T\|Giovannucci, Edward\|Fuchs, Charles S\|Wu, Kana\|Nishihara, Reiko\|O'Brien, Michael\|Ogino, Shuji
PMID:	24935274

977.
Journal:	Ann Oncol. 2014 Sep;25(9):1756-61.
Title:	Clinical activity of FOLFIRI plus cetuximab according to extended gene mutation status by next-generation sequencing: findings from the CAPRI-GOIM trial.
Author:	Ciardiello, F\|Normanno, N\|Maiello, E\|Martinelli, E\|Troiani, T\|Pisconti, S\|Giuliani, F\|Barone, C\|Carteni, G\|Rachiglio, A M\|Montesarchio, V\|Tonini, G\|Rizzi, D\|Cinieri, S\|Bordonaro, R\|Febbraro, A\|De Vita, F\|Orditura, M\|Fenizia, F\|Lambiase, M\|Rinaldi, A\|Tatan
PMID:	24942275

978.
Journal:	J Cancer Res Clin Oncol. 2014 Nov;140(11):1863-71.
Title:	The BRAF mutation is associated with the prognosis in colorectal cancer.
Author:	Ahn, Tae Sung\|Jeong, Dongjun\|Son, Myoung Won\|Jung, Haeil\|Park, Soyoung\|Kim, Hyungjoo\|Bae, Sang Byung\|Kim, Han Jo\|Jeon, Young-Woo\|Lee, Moon Soo\|Baek, Moo-Jun
PMID:	24942334

979.
Journal:	Clin Cancer Res. 2014 Aug 15;20(16):4251-61.
Title:	Phase I expansion and pharmacodynamic study of the oral MEK inhibitor RO4987655 (CH4987655) in selected patients with advanced cancer with RAS-RAF mutations.
Author:	Zimmer, Lisa\|Barlesi, Fabrice\|Martinez-Garcia, Maria\|Dieras, Veronique\|Schellens, Jan H M\|Spano, Jean-Philippe\|Middleton, Mark R\|Calvo, Emiliano\|Paz-Ares, Luiz\|Larkin, James\|Pacey, Simon\|Venturi, Miro\|Kraeber-Bodere, Francoise\|Tessier, Jean J L\|Eberhardt,
PMID:	24947927

980.
Journal:	Cancer. 2014 Nov 15;120(22):3446-56.
Title:	The MAPK pathway across different malignancies: a new perspective.
Author:	Burotto, Mauricio\|Chiou, Victoria L\|Lee, Jung-Min\|Kohn, Elise C
PMID:	24948110

981.
Journal:	Transl Oncol. 2014 Aug;7(4):456-63.
Title:	Claudin-1 Expression Is Elevated in Colorectal Cancer Precursor Lesions Harboring the BRAF V600E Mutation.
Author:	Caruso, Maria\|Fung, Kim Y C\|Moore, James\|Brierley, Gemma V\|Cosgrove, Leah J\|Thomas, Michelle\|Cheetham, Glenice\|Brook, Emma\|Fraser, Louise M\|Tin, Teresa\|Tran, Ha\|Ruszkiewicz, Andrew
PMID:	24954356

982.
Journal:	Cancer Control. 2014 Jul;21(3):221-30.
Title:	BRAF mutations: signaling, epidemiology, and clinical experience in multiple malignancies.
Author:	Hall, Richard D\|Kudchadkar, Ragini R
PMID:	24955706

983.
Journal:	J Natl Cancer Inst. 2014 Jun 23;106(7). pii: dju121.
Title:	TP53 mutational status and cetuximab benefit in rectal cancer: 5-year results of the EXPERT-C trial.
Author:	Sclafani, Francesco\|Gonzalez, David\|Cunningham, David\|Hulkki Wilson, Sanna\|Peckitt, Clare\|Tabernero, Josep\|Glimelius, Bengt\|Cervantes, Andres\|Dewdney, Alice\|Wotherspoon, Andrew\|Brown, Gina\|Tait, Diana\|Oates, Jacqueline\|Chau, Ian
PMID:	24957073

984.
Journal:	J Formos Med Assoc. 2014 Jul;113(7):417-21.
Title:	Hyperplastic polyps identified during screening endoscopy: reevaluated by histological examinations and genetic alterations.
Author:	Lin, Yang-Chao\|Chiu, Han-Mo\|Lee, Yi-Chia\|Shun, Chia-Tung\|Wang, Hsiu-Po\|Wu, Ming-Shiang
PMID:	24961182

985.
Journal:	J Surg Oncol. 2014 Sep;110(4):451-7.
Title:	The prognostic role of microsatellite instability, codon-specific KRAS, and BRAF mutations in colon cancer.
Author:	Lin, Chun-Chi\|Lin, Jen-Kou\|Lin, Tzu-Chen\|Chen, Wei-Shone\|Yang, Shung-Haur\|Wang, Huann-Sheng\|Lan, Yuan-Tzu\|Jiang, Jeng-Kai\|Yang, Muh-Hwa\|Chang, Shih-Ching
PMID:	24964758

986.
Journal:	BMC Cancer. 2014 Jun 25;14:466.
Title:	DNA methylation alterations of AXIN2 in serrated adenomas and colon carcinomas with microsatellite instability.
Author:	Muto, Yuta\|Maeda, Takafumi\|Suzuki, Koichi\|Kato, Takaharu\|Watanabe, Fumiaki\|Kamiyama, Hidenori\|Saito, Masaaki\|Koizumi, Kei\|Miyaki, Yuichiro\|Konishi, Fumio\|Alonso, Sergio\|Perucho, Manuel\|Rikiyama, Toshiki
PMID:	24964857

987.
Journal:	Int J Oncol. 2014 Sep;45(3):1167-74.
Title:	Next-generation sequencing analysis of lung and colon carcinomas reveals a variety of genetic alterations.
Author:	Chevrier, Sandy\|Arnould, Laurent\|Ghiringhelli, Francois\|Coudert, Bruno\|Fumoleau, Pierre\|Boidot, Romain
PMID:	24990411

988.
Journal:	Mol Cancer. 2014 Jul 8;13:168.
Title:	A very low incidence of BRAF mutations in Middle Eastern colorectal carcinoma.
Author:	Siraj, Abdul K\|Bu, Rong\|Prabhakaran, Sarita\|Bavi, Prashant\|Beg, Shaham\|Al Hazmi, Mohsen\|Al-Rasheed, Maha\|Alobaisi, Khadija\|Al-Dayel, Fouad\|AlManea, Hadeel\|Al-Sanea, Nasser\|Uddin, Shahab\|Al-Kuraya, Khawla S
PMID:	25005754

989.
Journal:	Ann Oncol. 2014 Oct;25(10):2008-14.
Title:	Clinicopathologic characteristics and gene expression analyses of non-KRAS 12/13, RAS-mutated metastatic colorectal cancer.
Author:	Morris, V K\|Lucas, F A San\|Overman, M J\|Eng, C\|Morelli, M P\|Jiang, Z-Q\|Luthra, R\|Meric-Bernstam, F\|Maru, D\|Scheet, P\|Kopetz, S\|Vilar, E
PMID:	25009008

990.
Journal:	PLoS One. 2014 Jul 10;9(7):e101957.
Title:	SOX2 expression is regulated by BRAF and contributes to poor patient prognosis in colorectal cancer.
Author:	Lundberg, Ida V\|Lofgren Burstrom, Anna\|Edin, Sofia\|Eklof, Vincy\|Oberg, Ake\|Stenling, Roger\|Palmqvist, Richard\|Wikberg, Maria L
PMID:	25010701

991.
Journal:	Clin Cancer Res. 2014 Sep 15;20(18):4962-70.
Title:	Excess of proximal microsatellite-stable colorectal cancer in African Americans from a multiethnic study.
Author:	Xicola, Rosa M\|Gagnon, Molly\|Clark, Julia R\|Carroll, Timothy\|Gao, Weihua\|Fernandez, Christian\|Mijic, Dragana\|Rawson, James B\|Janoski, Ashley\|Pusatcioglu, Cenk K\|Rajaram, Priyanka\|Gluskin, Adam B\|Regan, Maureen\|Chaudhry, Vivek\|Abcarian, Herand\|Blumetti, Je
PMID:	25013126

992.
Journal:	Oncol Lett. 2014 Aug;8(2):869-875.
Title:	BRAF-activated long non-coding RNA contributes to colorectal cancer migration by inducing epithelial-mesenchymal transition.
Author:	Guo, Qinhao\|Zhao, Yan\|Chen, Jiejing\|Hu, Jun\|Wang, Shuwei\|Zhang, Dongsheng\|Sun, Yueming
PMID:	25013510

993.
Journal:	Ann Surg Oncol. 2014 Dec;21(13):4164-73.
Title:	SMO expression in colorectal cancer: associations with clinical, pathological, and molecular features.
Author:	Li, Tingting\|Liao, Xiaoyun\|Lochhead, Paul\|Morikawa, Teppei\|Yamauchi, Mai\|Nishihara, Reiko\|Inamura, Kentaro\|Kim, Sun A\|Mima, Kosuke\|Sukawa, Yasutaka\|Kuchiba, Aya\|Imamura, Yu\|Baba, Yoshifumi\|Shima, Kaori\|Meyerhardt, Jeffrey A\|Chan, Andrew T\|Fuchs, Charles S
PMID:	25023548

994.
Journal:	Inflamm Bowel Dis. 2014 Sep;20(9):1584-92.
Title:	Small bowel adenocarcinomas complicating Crohn's disease are associated with dysplasia: a pathological and molecular study.
Author:	Svrcek, Magali\|Piton, Gael\|Cosnes, Jacques\|Beaugerie, Laurent\|Vermeire, Severine\|Geboes, Karel\|Lemoine, Antoinette\|Cervera, Pascale\|El-Murr, Nizar\|Dumont, Sylvie\|Scriva, Aurelie\|Lascols, Olivier\|Ardizzone, Sandro\|Fociani, Paolo\|Savoye, Guillaume\|Le Pessot
PMID:	25029614

995.
Journal:	Biomed Res Int. 2014;2014:591867.
Title:	Current approaches for predicting a lack of response to anti-EGFR therapy in KRAS wild-type patients.
Author:	Er, Tze-Kiong\|Chen, Chih-Chieh\|Bujanda, Luis\|Herreros-Villanueva, Marta
PMID:	25032217

996.
Journal:	Oncol Rep. 2014 Oct;32(4):1419-26.
Title:	KRAS and BRAF mutations and MSI status in precursor lesions of colorectal cancer detected by colonoscopy.
Author:	Yamane, L S\|Scapulatempo-Neto, C\|Alvarenga, L\|Oliveira, C Z\|Berardinelli, G N\|Almodova, E\|Cunha, T R\|Fava, G\|Colaiacovo, W\|Melani, A\|Fregnani, J H\|Reis, R M\|Guimaraes, D P
PMID:	25050586

997.
Journal:	Acta Med Indones. 2014 Apr;46(2):104-10.
Title:	Use of BRAF V600E as a molecular marker in aggressive colorectal cancer.
Author:	Hernowo, Bethy S\|Ariyanni, Fenny\|Suryanti, Sri\|Hassan, Abdul H
PMID:	25053682

998.
Journal:	Ann Oncol. 2014 Oct;25(10):1995-2001.
Title:	Distal and proximal colon cancers differ in terms of molecular, pathological, and clinical features.
Author:	Missiaglia, E\|Jacobs, B\|D'Ario, G\|Di Narzo, A F\|Soneson, C\|Budinska, E\|Popovici, V\|Vecchione, L\|Gerster, S\|Yan, P\|Roth, A D\|Klingbiel, D\|Bosman, F T\|Delorenzi, M\|Tejpar, S
PMID:	25057166

999.
Journal:	Clin Colorectal Cancer. 2014 Sep;13(3):164-71.
Title:	Progression-free survival remains poor over sequential lines of systemic therapy in patients with BRAF-mutated colorectal cancer.
Author:	Morris, Van\|Overman, Michael J\|Jiang, Zhi-Qin\|Garrett, Christopher\|Agarwal, Shweta\|Eng, Cathy\|Kee, Bryan\|Fogelman, David\|Dasari, Arvind\|Wolff, Robert\|Maru, Dipen\|Kopetz, Scott
PMID:	25069797

1000.
Journal:	Med Oncol. 2014 Sep;31(9):124.
Title:	Molecular spectrum of KRAS, BRAF, and PIK3CA gene mutation: determination of frequency, distribution pattern in Indian colorectal carcinoma.
Author:	Bisht, Swati\|Ahmad, Firoz\|Sawaimoon, Satyakam\|Bhatia, Simi\|Das, Bibhu Ranjan
PMID:	25073438

1001.
Journal:	Tumori. 2014 May-Jun;100(3):315-20.
Title:	BRAF mutation analysis is a valid tool to implement in Lynch syndrome diagnosis in patients classified according to the Bethesda guidelines.
Author:	Molinari, Francesca\|Signoroni, Stefano\|Lampis, Andrea\|Bertan, Claudia\|Perrone, Federica\|Sala, Paola\|Mondini, Patrizia\|Crippa, Stefano\|Bertario, Lucio\|Frattini, Milo
PMID:	25076244

1002.
Journal:	PLoS One. 2014 Aug 1;9(8):e103159.
Title:	Sporadic early-onset colorectal cancer is a specific sub-type of cancer: a morphological, molecular and genetics study.
Author:	Kirzin, Sylvain\|Marisa, Laetitia\|Guimbaud, Rosine\|De Reynies, Aurelien\|Legrain, Michele\|Laurent-Puig, Pierre\|Cordelier, Pierre\|Pradere, Bernard\|Bonnet, Delphine\|Meggetto, Fabienne\|Portier, Guillaume\|Brousset, Pierre\|Selves, Janick
PMID:	25083765

1003.
Journal:	PLoS One. 2014 Aug 5;9(8):e103822.
Title:	Distinct molecular features of different macroscopic subtypes of colorectal neoplasms.
Author:	Konda, Kenichi\|Konishi, Kazuo\|Yamochi, Toshiko\|Ito, Yoichi M\|Nozawa, Hisako\|Tojo, Masayuki\|Shinmura, Kensuke\|Kogo, Mari\|Katagiri, Atsushi\|Kubota, Yutaro\|Muramoto, Takashi\|Yano, Yuichiro\|Kobayashi, Yoshiya\|Kihara, Toshihiro\|Tagawa, Teppei\|Makino, Reiko\|Tak
PMID:	25093594

1004.
Journal:	Pathologe. 2014 Nov;35(6):615-21; quiz 622-3.
Title:	[Colorectal carcinoma in consideration of the new German S3 guideline 2013].
Author:	Neumann, J H L\|Kirchner, T
PMID:	25106124

1005.
Journal:	World J Gastroenterol. 2014 Aug 7;20(29):9732-43.
Title:	Beyond KRAS: Predictive factors of the efficacy of anti-EGFR monoclonal antibodies in the treatment of metastatic colorectal cancer.
Author:	De Stefano, Alfonso\|Carlomagno, Chiara
PMID:	25110411

1006.
Journal:	World J Gastroenterol. 2014 Aug 7;20(29):10050-61.
Title:	IGF2 differentially methylated region hypomethylation in relation to pathological and molecular features of serrated lesions.
Author:	Naito, Takafumi\|Nosho, Katsuhiko\|Ito, Miki\|Igarashi, Hisayoshi\|Mitsuhashi, Kei\|Yoshii, Shinji\|Aoki, Hironori\|Nomura, Masafumi\|Sukawa, Yasutaka\|Yamamoto, Eiichiro\|Adachi, Yasushi\|Takahashi, Hiroaki\|Hosokawa, Masao\|Fujita, Masahiro\|Takenouchi, Toshinao\|Maru
PMID:	25110432

1007.
Journal:	J Natl Cancer Inst. 2014 Aug 11;106(8). pii: dju180.
Title:	Re: Microsatellite instability and BRAF mutation testing in colorectal cancer prognostication.
Author:	Rosty, Christophe\|Williamson, Elizabeth J\|Clendenning, Mark\|Walters, Rhiannon J\|Walsh, Michael D\|Win, Aung K\|Jenkins, Mark A\|Hopper, John L\|Winship, Ingrid\|Southey, Melissa C\|Giles, Graham G\|English, Dallas R\|Buchanan, Daniel D
PMID:	25114271

1008.
Journal:	Cancer Med. 2014 Dec;3(6):1527-38.
Title:	Mutations in POLE and survival of colorectal cancer patients--link to disease stage and treatment.
Author:	Stenzinger, Albrecht\|Pfarr, Nicole\|Endris, Volker\|Penzel, Roland\|Jansen, Lina\|Wolf, Thomas\|Herpel, Esther\|Warth, Arne\|Klauschen, Frederick\|Kloor, Matthias\|Roth, Wilfried\|Blaker, Hendrik\|Chang-Claude, Jenny\|Brenner, Hermann\|Hoffmeister, Michael\|Weichert, W
PMID:	25124163

1009.
Journal:	Surg Oncol. 2014 Sep;23(3):167-76.
Title:	The clinical perspectives of CDX2 expression in colorectal cancer: a qualitative systematic review.
Author:	Olsen, J\|Espersen, M L M\|Jess, P\|Kirkeby, L T\|Troelsen, J T
PMID:	25126956

1010.
Journal:	PLoS One. 2014 Aug 25;9(8):e106105.
Title:	A further investigation of combined mismatch repair and BRAFV600E mutation specific immunohistochemistry as a predictor of overall survival in colorectal carcinoma.
Author:	Luey, Nathan\|Toon, Christopher W\|Sioson, Loretta\|Clarkson, Adele\|Watson, Nicole\|Cussigh, Carmen\|Kedziora, Andrew\|Pincott, Stuart\|Pillinger, Stephen\|Evans, Justin\|Percy, John\|Engel, Alexander\|Schnitzler, Margaret\|Gill, Anthony J
PMID:	25153715

1011.
Journal:	J Surg Oncol. 2014 Dec;110(8):982-8.
Title:	Combined microsatellite instability and BRAF gene status as biomarkers for adjuvant chemotherapy in stage III colorectal cancer.
Author:	Ooki, Akira\|Akagi, Kiwamu\|Yatsuoka, Toshimasa\|Asayama, Masako\|Hara, Hiroki\|Takahashi, Akemi\|Kakuta, Miho\|Nishimura, Yoji\|Yamaguchi, Kensei
PMID:	25154726

1012.
Journal:	Biomed Res Int. 2014;2014:629496.
Title:	Epithelial-mesenchymal transition and somatic alteration in colorectal cancer with and without peritoneal carcinomatosis.
Author:	Shelygin, Y A\|Pospekhova, N I\|Shubin, V P\|Kashnikov, V N\|Frolov, S A\|Sushkov, O I\|Achkasov, S I\|Tsukanov, A S
PMID:	25157365

1013.
Journal:	Genome Biol. 2014 Aug 28;15(8):454.
Title:	Comparative sequencing analysis reveals high genomic concordance between matched primary and metastatic colorectal cancer lesions.
Author:	Brannon, A Rose\|Vakiani, Efsevia\|Sylvester, Brooke E\|Scott, Sasinya N\|McDermott, Gregory\|Shah, Ronak H\|Kania, Krishan\|Viale, Agnes\|Oschwald, Dayna M\|Vacic, Vladimir\|Emde, Anne-Katrin\|Cercek, Andrea\|Yaeger, Rona\|Kemeny, Nancy E\|Saltz, Leonard B\|Shia, Jinru
PMID:	25164765

1014.
Journal:	Pathol Res Pract. 2014 Dec;210(12):893-6.
Title:	Copy number alterations of chromosomal regions enclosing protein tyrosine phosphatase receptor-like genes in colorectal cancer.
Author:	Laczmanska, Izabela\|Karpinski, Pawel\|Kozlowska, Joanna\|Bebenek, Marek\|Ramsey, David\|Sedziak, Tomasz\|Ziolkowski, Piotr\|Sasiadek, Maria M
PMID:	25169130

1015.
Journal:	J Geriatr Oncol. 2014 Oct 1;5(4):384-8.
Title:	High prevalence of deficient mismatch repair phenotype and the V600E BRAF mutation in elderly patients with colorectal cancer.
Author:	Aparicio, Thomas\|Schischmanoff, Olivier\|Poupardin, Cecile\|Mary, Florence\|Soufir, Nadem\|Barrat, Christophe\|Bellaiche, Guy\|Boubaya, Marouane\|Choudat, Laurence\|Cucherousset, Joel\|DesGuetz, Gaetan\|Wind, Philippe\|Benamouzig, Robert
PMID:	25176643

1016.
Journal:	Clin Cancer Res. 2014 Sep 1;20(17):4499-4510.
Title:	A let-7 microRNA-binding site polymorphism in KRAS predicts improved outcome in patients with metastatic colorectal cancer treated with salvage cetuximab/panitumumab monotherapy.
Author:	Saridaki, Zenia\|Weidhaas, Joanne B\|Lenz, Heinz-Josef\|Laurent-Puig, Pierre\|Jacobs, Bart\|De Schutter, Jef\|De Roock, Wendy\|Salzman, David W\|Zhang, Wu\|Yang, Dongyun\|Pilati, Camilla\|Bouche, Olivier\|Piessevaux, Hubert\|Tejpar, Sabine
PMID:	25183481

1017.
Journal:	J Natl Cancer Inst. 2014 Sep 4;106(9). pii: dju195.
Title:	Tumor LINE-1 methylation level and microsatellite instability in relation to colorectal cancer prognosis.
Author:	Inamura, Kentaro\|Yamauchi, Mai\|Nishihara, Reiko\|Lochhead, Paul\|Qian, Zhi Rong\|Kuchiba, Aya\|Kim, Sun A\|Mima, Kosuke\|Sukawa, Yasutaka\|Jung, Seungyoun\|Zhang, Xuehong\|Wu, Kana\|Cho, Eunyoung\|Chan, Andrew T\|Meyerhardt, Jeffrey A\|Harris, Curtis C\|Fuchs, Charles
PMID:	25190725

1018.
Journal:	Zhonghua Bing Li Xue Za Zhi. 2014 Jun;43(6):394-8.
Title:	[Screening for Lynch syndrome in colorectal cancer].
Author:	Liu, Xiaohong\|Cao, Yongcheng\|Wang, Cuicui\|Cao, Ruixue\|Chen, Xin\|Ding, Jiyuan\|Geng, Ming
PMID:	25208990

1019.
Journal:	World J Gastroenterol. 2014 Sep 14;20(34):12346-9.
Title:	MicroRNA-31 expression in colorectal serrated pathway progression.
Author:	Aoki, Hironori\|Nosho, Katsuhiko\|Igarashi, Hisayoshi\|Ito, Miki\|Mitsuhashi, Kei\|Naito, Takafumi\|Yamamoto, Eiichiro\|Tanuma, Tokuma\|Nomura, Masafumi\|Maguchi, Hiroyuki\|Shinohara, Toshiya\|Suzuki, Hiromu\|Yamamoto, Hiroyuki\|Shinomura, Yasuhisa
PMID:	25232271

1020.
Journal:	Cancer Res. 2014 Nov 15;74(22):6693-704.
Title:	TRAP1 is involved in BRAF regulation and downstream attenuation of ERK phosphorylation and cell-cycle progression: a novel target for BRAF-mutated colorectal tumors.
Author:	Condelli, Valentina\|Piscazzi, Annamaria\|Sisinni, Lorenza\|Matassa, Danilo Swann\|Maddalena, Francesca\|Lettini, Giacomo\|Simeon, Vittorio\|Palladino, Giuseppe\|Amoroso, Maria Rosaria\|Trino, Stefania\|Esposito, Franca\|Landriscina, Matteo
PMID:	25239454

1021.
Journal:	Health Technol Assess. 2014 Sep;18(58):1-406.
Title:	A systematic review and economic evaluation of diagnostic strategies for Lynch syndrome.
Author:	Snowsill, Tristan\|Huxley, Nicola\|Hoyle, Martin\|Jones-Hughes, Tracey\|Coelho, Helen\|Cooper, Chris\|Frayling, Ian\|Hyde, Chris
PMID:	25244061

1022.
Journal:	Ann Surg Treat Res. 2014 Sep;87(3):123-30.
Title:	hMLH1 promoter methylation and BRAF mutations in high-frequency microsatellite instability colorectal cancers not fulfilling the revised Bethesda guidelines.
Author:	Kim, Sang Jin\|Kim, Hyoung Ran\|Kim, Seok Hyung\|Han, Ji Hye\|Cho, Yong Beom\|Yun, Seong Hyeon\|Lee, Woo Yong\|Kim, Hee Cheol
PMID:	25247165

1023.
Journal:	PLoS One. 2014 Sep 23;9(9):e108193.
Title:	3'-Deoxy-3'-[18F]-Fluorothymidine PET imaging reflects PI3K-mTOR-mediated pro-survival response to targeted therapy in colorectal cancer.
Author:	McKinley, Eliot T\|Zhao, Ping\|Coffey, Robert J\|Washington, M Kay\|Manning, H Charles
PMID:	25247710

1024.
Journal:	Clin Biochem. 2014 Dec;47(18):340-3.
Title:	High-throughput screening of extended RAS mutations based on high-resolution melting analysis for prediction of anti-EGFR treatment efficacy in colorectal carcinoma.
Author:	Ishige, Takayuki\|Itoga, Sakae\|Sato, Kenichi\|Kitamura, Kouichi\|Nishimura, Motoi\|Sawai, Setsu\|Matsushita, Kazuyuki\|Suzuki, Kazufumi\|Ota, Satoshi\|Miyauchi, Hideaki\|Matsubara, Hisahiro\|Nakatani, Yukio\|Nomura, Fumio
PMID:	25262986

1025.
Journal:	Diagn Pathol. 2014 Sep 30;9:187.
Title:	KRAS and BRAF mutational status in colon cancer from Albanian patients.
Author:	Martinetti, Daniela\|Costanzo, Rosario\|Kadare, Shahin\|Alimehmeti, Mehdiu\|Colarossi, Cristina\|Canzonieri, Vincenzo\|Berretta, Massimiliano\|Memeo, Lorenzo
PMID:	25267307

1026.
Journal:	Int J Mol Sci. 2014 Sep 29;15(10):17344-65.
Title:	Gender-associated genomic differences in colorectal cancer: clinical insight from feminization of male cancer cells.
Author:	Ali, Rola H\|Marafie, Makia J\|Bitar, Milad S\|Al-Dousari, Fahad\|Ismael, Samar\|Bin Haider, Hussain\|Al-Ali, Waleed\|Jacob, Sindhu P\|Al-Mulla, Fahd
PMID:	25268611

1027.
Journal:	Oncotarget. 2014 Oct 15;5(19):9444-59.
Title:	miR-524-5p suppresses the growth of oncogenic BRAF melanoma by targeting BRAF and ERK2.
Author:	Liu, Szu-Mam\|Lu, Jean\|Lee, Hoong-Chien\|Chung, Feng-Hsiang\|Ma, Nianhan
PMID:	25275294

1028.
Journal:	J Med Genet. 2014 Dec;51(12):789-96.
Title:	Tumour MLH1 promoter region methylation testing is an effective prescreen for Lynch Syndrome (HNPCC).
Author:	Newton, K\|Jorgensen, N M\|Wallace, A J\|Buchanan, D D\|Lalloo, F\|McMahon, R F T\|Hill, J\|Evans, D G
PMID:	25280751

1029.
Journal:	Acta Neuropathol. 2014 Dec;128(6):879-91.
Title:	Predictive molecular markers in metastases to the central nervous system: recent advances and future avenues.
Author:	Berghoff, Anna Sophie\|Bartsch, Rupert\|Wohrer, Adelheid\|Streubel, Berthold\|Birner, Peter\|Kros, Johan M\|Brastianos, Priscilla K\|von Deimling, Andreas\|Preusser, Matthias
PMID:	25287912

1030.
Journal:	Cancer Discov. 2014 Nov;4(11):1269-80.
Title:	Resistance to anti-EGFR therapy in colorectal cancer: from heterogeneity to convergent evolution.
Author:	Misale, Sandra\|Di Nicolantonio, Federica\|Sartore-Bianchi, Andrea\|Siena, Salvatore\|Bardelli, Alberto
PMID:	25293556

1031.
Journal:	Biomed Res Int. 2014;2014:568693.
Title:	Biological and molecular effects of small molecule kinase inhibitors on low-passage human colorectal cancer cell lines.
Author:	Lange, Falko\|Franz, Benjamin\|Maletzki, Claudia\|Linnebacher, Michael\|Huhns, Maja\|Jaster, Robert
PMID:	25309914

1032.
Journal:	J Natl Compr Canc Netw. 2014 Oct;12(10):1433-42.
Title:	Predictive biomarkers for anti-epidermal growth factor receptor therapy: beyond KRAS testing.
Author:	Ashraf, Noman\|Kothari, Nishi\|Kim, Richard
PMID:	25313182

1033.
Journal:	Onco Targets Ther. 2014 Oct 4;7:1817-28.
Title:	Colorectal cancer in Chinese patients: current and emerging treatment options.
Author:	Li, Leung\|Ma, Brigette By
PMID:	25336973

1034.
Journal:	Int J Clin Exp Pathol. 2014 Aug 15;7(9):5927-39. eCollection 2014.
Title:	Comparison of neuroendocrine differentiation and KRAS/NRAS/BRAF/PIK3CA/TP53 mutation status in primary and metastatic colorectal cancer.
Author:	Kleist, Britta\|Kempa, Marcel\|Novy, Michael\|Oberkanins, Christian\|Xu, Li\|Li, Guojun\|Loland, Christiane\|Poetsch, Micaela
PMID:	25337237

1035.
Journal:	Mol Cancer Ther. 2014 Dec;13(12):3230-40.
Title:	Cancer in silico drug discovery: a systems biology tool for identifying candidate drugs to target specific molecular tumor subtypes.
Author:	San Lucas, F Anthony\|Fowler, Jerry\|Chang, Kyle\|Kopetz, Scott\|Vilar, Eduardo\|Scheet, Paul
PMID:	25349306

1036.
Journal:	Oncotarget. 2014 Dec 15;5(23):11752-77.
Title:	BRAF vs RAS oncogenes: are mutations of the same pathway equal? Differential signalling and therapeutic implications.
Author:	Oikonomou, Eftychia\|Koustas, Evangelos\|Goulielmaki, Maria\|Pintzas, Alexander
PMID:	25361007

1037.
Journal:	BMC Cancer. 2014 Nov 3;14:802.
Title:	BRAF V600E mutation and KRAS codon 13 mutations predict poor survival in Chinese colorectal cancer patients.
Author:	Chen, Jing\|Guo, Fang\|Shi, Xin\|Zhang, Lihua\|Zhang, Aifeng\|Jin, Hui\|He, Youji
PMID:	25367198

1038.
Journal:	Cancer Discov. 2014 Nov;4(11):OF11.
Title:	MAFG mediates CIMP in BRAF-mutant colorectal cancer.
Author:
PMID:	25367952

1039.
Journal:	Neoplasia. 2014 Oct 23;16(10):814-23.
Title:	The presence of telomere fusion in sporadic colon cancer independently of disease stage, TP53/KRAS mutation status, mean telomere length, and telomerase activity.
Author:	Tanaka, Hiromi\|Beam, Matthew J\|Caruana, Kevin
PMID:	25379018

1040.
Journal:	Neoplasia. 2014 Oct 23;16(10):845-60.
Title:	Resistance to Selumetinib (AZD6244) in colorectal cancer cell lines is mediated by p70S6K and RPS6 activation.
Author:	Grasso, Silvina\|Tristante, Elena\|Saceda, Miguel\|Carbonell, Pablo\|Mayor-Lopez, Leticia\|Carballo-Santana, Mar\|Carrasco-Garcia, Estefania\|Rocamora-Reverte, Lourdes\|Garcia-Morales, Pilar\|Carballo, Fernando\|Ferragut, Jose A\|Martinez-Lacaci, Isabel
PMID:	25379021

1041.
Journal:	Curr Colorectal Cancer Rep. 2014 Sep 1;10(3):346-353.
Title:	Prognostic Impact of Deficient DNA Mismatch Repair and Mutations in KRAS, and BRAF(V600E) in Patients with Lymph Node-Positive Colon Cancer.
Author:	Zaanan, Aziz\|Bachet, Jean-Baptiste\|Andre, Thierry\|Sinicrope, Frank A
PMID:	25386108

1042.
Journal:	Zhonghua Wei Chang Wai Ke Za Zhi. 2014 Nov;17(11):1081-6.
Title:	[Safety and efficacy analysis on modified FOLFOXIRI as first-line treatment for advanced colorectal cancer in China-single center experience].
Author:	Cai, Yue\|Hu, Huabin\|Wang, Wenjing\|Cao, Taiyuan\|Deng, Yanhong
PMID:	25421765

1043.
Journal:	Oncol Res Treat. 2014;37(11):646-52.
Title:	Efficacy of triplet combination chemotherapy with oxaliplatin, irinotecan and capecitabine (OCX) in metastatic colorectal cancer in relation to RAS/RAF mutation status: results of a retrospective analysis.
Author:	Brunner, Stefan\|von Moos, Roger\|Mey, Ulrich\|Camenisch Gross, Ulrike\|Freyholdt, Tobias\|Cathomas, Richard
PMID:	25427581

1044.
Journal:	BMC Cancer. 2014 Nov 29;14:891.
Title:	Boosting Wnt activity during colorectal cancer progression through selective hypermethylation of Wnt signaling antagonists.
Author:	Silva, Ana-Luisa\|Dawson, Sarah N\|Arends, Mark J\|Guttula, Kiran\|Hall, Nigel\|Cameron, Ewen A\|Huang, Tim H-M\|Brenton, James D\|Tavare, Simon\|Bienz, Mariann\|Ibrahim, Ashraf E K
PMID:	25432628

1045.
Journal:	MAbs. 2014;6(6):1571-84.
Title:	CEA/CD3 bispecific antibody MEDI-565/AMG 211 activation of T cells and subsequent killing of human tumors is independent of mutations commonly found in colorectal adenocarcinomas.
Author:	Oberst, Michael D\|Fuhrmann, Stacy\|Mulgrew, Kathy\|Amann, Maria\|Cheng, Lily\|Lutterbuese, Petra\|Richman, Laura\|Coats, Steve\|Baeuerle, Patrick A\|Hammond, Scott A
PMID:	25484061

1046.
Journal:	Epigenetics. 2014 Nov;9(11):1454-60.
Title:	Isocitrate dehydrogenase 1 R132C mutation occurs exclusively in microsatellite stable colorectal cancers with the CpG island methylator phenotype.
Author:	Whitehall, V L J\|Dumenil, T D\|McKeone, D M\|Bond, C E\|Bettington, M L\|Buttenshaw, R L\|Bowdler, L\|Montgomery, G W\|Wockner, L F\|Leggett, B A
PMID:	25496513

1047.
Journal:	World J Clin Cases. 2014 Dec 16;2(12):835-9.
Title:	Role of MGMT as biomarker in colorectal cancer.
Author:	Inno, Alessandro\|Fanetti, Giuseppe\|Di Bartolomeo, Maria\|Gori, Stefania\|Maggi, Claudia\|Cirillo, Massimo\|Iacovelli, Roberto\|Nichetti, Federico\|Martinetti, Antonia\|de Braud, Filippo\|Bossi, Ilaria\|Pietrantonio, Filippo
PMID:	25516857

1048.
Journal:	Int J Clin Exp Pathol. 2014 Oct 15;7(11):7319-22. eCollection 2014.
Title:	BRAF mutation as a potential marker to identify the proximal colon serrated polyps with malignant potential.
Author:	Fu, Xiangsheng\|Zhang, Xiaoyan
PMID:	25550768

1049.
Journal:	Front Surg. 2015 Jan 5;1:50.
Title:	Immunohistochemistry - microarray analysis of patients with peritoneal metastases of appendiceal or colorectal origin.
Author:	Green, Danielle E\|Jayakrishnan, Thejus T\|Hwang, Michael\|Pappas, Sam G\|Gamblin, T Clark\|Turaga, Kiran K
PMID:	25593974

1050.
Journal:	Rev Gastroenterol Peru. 2014 Oct-Dec;34(4):299-303.
Title:	[Molecular characterization of hereditary colorectal cancer in Peru].
Author:	Nique Carbajal, Cesar\|Sanchez Renteria, Fernando\|Lettiero, Barbara\|Wernhoff, Patrik\|Dominguez-Valentin, Mev
PMID:	25594752

1051.
Journal:	Pol J Pathol. 2014 Dec;65(4):257-66.
Title:	Molecular pathology of colorectal cancer.
Author:	Bosman, Ft\|Yan, P
PMID:	25693079

1052.
Journal:	Eksp Klin Gastroenterol. 2014;(7):4-12.
Title:	[The alternative way of colorectal cancer developing. The histogenetic and molecular features of serrated lesions (review, continued)].
Author:	Ageikina, N V\|Duvanskii, V A\|Kniazev, M V\|Mal'kov, P G\|Danilova, N V\|Kharlova, O A
PMID:	25842399

1053.
Journal:
Title:
Author:	Meleth, Sreelatha\|Reeder-Hayes, Katherine\|Ashok, Mahima\|Clark, Robert\|Funkhouser, William\|Wines, Roberta\|Hill, Christine\|Shanahan, Ellen\|McClure, Emily\|Burson, Katrina\|Coker-Schwimmer, Manny\|Garge, Nikhil\|Jonas, Daniel E
PMID:	25905152

1054.
Journal:	Pak J Biol Sci. 2014 Apr;17(4):565-9.
Title:	High frequency of BRAF proto-oncogene hot spot mutation V600E in cohort of colorectal cancer patients from Ahvaz City, southwest Iran.
Author:	Asl, Javad Mohammadi\|Almasi, Shekoufeh\|Tabatabaiefar, Mohammad Amin
PMID:	25911848

1055.
Journal:	Bull Acad Natl Med. 2014 Jan;198(1):101-17.
Title:	[Genome sequencing and personalized medicine: perspectives and limitations].
Author:	Le Gall, Jean-Yves\|Debre, Patrice
PMID:	26259290

1056.
Journal:	Indian J Cancer. 2014 Oct-Dec;51(4):531-7.
Title:	Prevalence of KRAS mutations in metastatic colorectal cancer: A retrospective observational study from India.
Author:	Veldore, V H\|Rao, M R\|Prabhudesai, S A\|Tejaswi, R\|Kakara, S\|Pattanayak, S\|Krishnamoorthy, N\|Tejaswini, B N\|Hazarika, D\|Gangoli, A\|Rahman, S M\|Dixit, J\|Naik, R\|Diwakar, R B\|Satheesh, C T\|Shashidhara, H P\|Patil, S\|Gopinath, K S\|Kumar, B S
PMID:	26842186

1057.
Journal:	Biomedicines. 2014 Nov 25;2(4):345-358.
Title:	Role of HGF-MET Signaling in Primary and Acquired Resistance to Targeted Therapies in Cancer.
Author:	Della Corte, Carminia Maria\|Fasano, Morena\|Papaccio, Federica\|Ciardiello, Fortunato\|Morgillo, Floriana
PMID:	28548075

1058.
Journal:	Oncogene. 2015 Jan 22;34(4):531-6.
Title:	A chromatin modifier genetic screen identifies SIRT2 as a modulator of response to targeted therapies through the regulation of MEK kinase activity.
Author:	Bajpe, P K\|Prahallad, A\|Horlings, H\|Nagtegaal, I\|Beijersbergen, R\|Bernards, R
PMID:	24469059

1059.
Journal:	Int J Cancer. 2015 Jan 1;136(1):83-90.
Title:	Role of NRAS mutations as prognostic and predictive markers in metastatic colorectal cancer.
Author:	Schirripa, Marta\|Cremolini, Chiara\|Loupakis, Fotios\|Morvillo, Manfredi\|Bergamo, Francesca\|Zoratto, Federica\|Salvatore, Lisa\|Antoniotti, Carlotta\|Marmorino, Federica\|Sensi, Elisa\|Lupi, Cristiana\|Fontanini, Gabriella\|De Gregorio, Veronica\|Giannini, Riccardo
PMID:	24806288

1060.
Journal:	Target Oncol. 2015 Mar;10(1):99-109.
Title:	A mutant BRAF V600E-specific immunohistochemical assay: correlation with molecular mutation status and clinical outcome in colorectal cancer.
Author:	Day, Fiona\|Muranyi, Andrea\|Singh, Shalini\|Shanmugam, Kandavel\|Williams, David\|Byrne, David\|Pham, Kym\|Palmieri, Michelle\|Tie, Jeanne\|Grogan, Thomas\|Gibbs, Peter\|Sieber, Oliver\|Waring, Paul\|Desai, Jayesh
PMID:	24859797

1061.
Journal:	Gut. 2015 Apr;64(4):627-35.
Title:	Fluorescence virus-guided capturing system of human colorectal circulating tumour cells for non-invasive companion diagnostics.
Author:	Shigeyasu, Kunitoshi\|Tazawa, Hiroshi\|Hashimoto, Yuuri\|Mori, Yoshiko\|Nishizaki, Masahiko\|Kishimoto, Hiroyuki\|Nagasaka, Takeshi\|Kuroda, Shinji\|Urata, Yasuo\|Goel, Ajay\|Kagawa, Shunsuke\|Fujiwara, Toshiyoshi
PMID:	24870621

1062.
Journal:	Ann Surg Oncol. 2015 Jan;22(1):187-94.
Title:	KRAS mutation is associated with worse prognosis in stage III or high-risk stage II colon cancer patients treated with adjuvant FOLFOX.
Author:	Lee, Dae-Won\|Kim, Kyung Ju\|Han, Sae-Won\|Lee, Hyun Jung\|Rhee, Ye Young\|Bae, Jeong Mo\|Cho, Nam-Yun\|Lee, Kyung-Hun\|Kim, Tae-Yong\|Oh, Do-Youn\|Im, Seock-Ah\|Bang, Yung-Jue\|Jeong, Seung-Yong\|Park, Kyu Joo\|Park, Jae-Gahb\|Kang, Gyeong Hoon\|Kim, Tae-You
PMID:	24889488

1063.
Journal:	Mod Pathol. 2015 Jan;28(1):146-58.
Title:	Distinct WNT/beta-catenin signaling activation in the serrated neoplasia pathway and the adenoma-carcinoma sequence of the colorectum.
Author:	Murakami, Takashi\|Mitomi, Hiroyuki\|Saito, Tsuyoshi\|Takahashi, Michiko\|Sakamoto, Naoto\|Fukui, Naoshi\|Yao, Takashi\|Watanabe, Sumio
PMID:	24925057

1064.
Journal:	Mod Pathol. 2015 Feb;28(2):268-78.
Title:	Aberrant expression of annexin A10 is closely related to gastric phenotype in serrated pathway to colorectal carcinoma.
Author:	Tsai, Jia-Huei\|Lin, Yu-Lin\|Cheng, Yi-Chen\|Chen, Chien-Chuan\|Lin, Liang-In\|Tseng, Li-Hui\|Cheng, Mei-Ling\|Liau, Jau-Yu\|Jeng, Yung-Ming
PMID:	25081749

1065.
Journal:	Oncogene. 2015 Jun 11;34(24):3164-75.
Title:	Transgenic expression of oncogenic BRAF induces loss of stem cells in the mouse intestine, which is antagonized by beta-catenin activity.
Author:	Riemer, P\|Sreekumar, A\|Reinke, S\|Rad, R\|Schafer, R\|Sers, C\|Blaker, H\|Herrmann, B G\|Morkel, M
PMID:	25109331

1066.
Journal:	Target Oncol. 2015 Jun;10(2):179-88.
Title:	Targeting BRAF mutant metastatic colorectal cancer: clinical implications and emerging therapeutic strategies.
Author:	Tie, Jeanne\|Desai, Jayesh
PMID:	25119972

1067.
Journal:	Int J Cancer. 2015 Mar 15;136(6):E559-68.
Title:	Comprehensive screening for mutations associated with colorectal cancer in unselected cases reveals penetrant and nonpenetrant mutations.
Author:	Kraus, Cornelia\|Rau, Tilman T\|Lux, Philipp\|Erlenbach-Wunsch, Katharina\|Lohr, Sabine\|Krumbiegel, Mandy\|Thiel, Christian T\|Stohr, Robert\|Agaimy, Abbas\|Croner, Roland S\|Sturzl, Michael\|Hohenberger, Werner\|Hartmann, Arndt\|Reis, Andre
PMID:	25142776

1068.
Journal:	Mod Pathol. 2015 Mar;28(3):414-27.
Title:	A clinicopathological and molecular analysis of 200 traditional serrated adenomas.
Author:	Bettington, Mark L\|Walker, Neal I\|Rosty, Christophe\|Brown, Ian S\|Clouston, Andrew D\|McKeone, Diane M\|Pearson, Sally-Ann\|Klein, Kerenaftali\|Leggett, Barbara A\|Whitehall, Vicki L J
PMID:	25216220

1069.
Journal:	Clin Cancer Res. 2015 Mar 1;21(5):1087-97.
Title:	Clinical relevance of KRAS-mutated subclones detected with picodroplet digital PCR in advanced colorectal cancer treated with anti-EGFR therapy.
Author:	Laurent-Puig, Pierre\|Pekin, Deniz\|Normand, Corinne\|Kotsopoulos, Steve K\|Nizard, Philippe\|Perez-Toralla, Karla\|Rowell, Rachel\|Olson, Jeff\|Srinivasan, Preethi\|Le Corre, Delphine\|Hor, Thevy\|El Harrak, Zakaria\|Li, Xinyu\|Link, Darren R\|Bouche, Olivier\|Emile, J
PMID:	25248381

1070.
Journal:	Cancer. 2015 Jan 1;121(1):34-42.
Title:	Identification of novel mutations by exome sequencing in African American colorectal cancer patients.
Author:	Ashktorab, Hassan\|Daremipouran, Mohammad\|Devaney, Joe\|Varma, Sudhir\|Rahi, Hamed\|Lee, Edward\|Shokrani, Babak\|Schwartz, Russell\|Nickerson, Michael L\|Brim, Hassan
PMID:	25250560

1071.
Journal:	Br J Cancer. 2015 Jan 6;112(1):24-31.
Title:	A phase I trial of vertical inhibition of IGF signalling using cixutumumab, an anti-IGF-1R antibody, and selumetinib, an MEK 1/2 inhibitor, in advanced solid tumours.
Author:	Wilky, B A\|Rudek, M A\|Ahmed, S\|Laheru, D A\|Cosgrove, D\|Donehower, R C\|Nelkin, B\|Ball, D\|Doyle, L A\|Chen, H\|Ye, X\|Bigley, G\|Womack, C\|Azad, N S
PMID:	25268371

1072.
Journal:	Gastroenterology. 2015 Jan;148(1):77-87.e2.
Title:	Association between molecular subtypes of colorectal cancer and patient survival.
Author:	Phipps, Amanda I\|Limburg, Paul J\|Baron, John A\|Burnett-Hartman, Andrea N\|Weisenberger, Daniel J\|Laird, Peter W\|Sinicrope, Frank A\|Rosty, Christophe\|Buchanan, Daniel D\|Potter, John D\|Newcomb, Polly A
PMID:	25280443

1073.
Journal:	Gastroenterology. 2015 Jan;148(1):88-99.
Title:	Molecular markers identify subtypes of stage III colon cancer associated with patient outcomes.
Author:	Sinicrope, Frank A\|Shi, Qian\|Smyrk, Thomas C\|Thibodeau, Stephen N\|Dienstmann, Rodrigo\|Guinney, Justin\|Bot, Brian M\|Tejpar, Sabine\|Delorenzi, Mauro\|Goldberg, Richard M\|Mahoney, Michelle\|Sargent, Daniel J\|Alberts, Steven R
PMID:	25305506

1074.
Journal:	Br J Cancer. 2015 Jan 20;112(2):403-12.
Title:	B-RAF mutation and accumulated gene methylation in aberrant crypt foci (ACF), sessile serrated adenoma/polyp (SSA/P) and cancer in SSA/P.
Author:	Inoue, A\|Okamoto, K\|Fujino, Y\|Nakagawa, T\|Muguruma, N\|Sannomiya, K\|Mitsui, Y\|Takaoka, T\|Kitamura, S\|Miyamoto, H\|Okahisa, T\|Fujimori, T\|Imoto, I\|Takayama, T
PMID:	25314065

1075.
Journal:	Tumour Biol. 2015 Feb;36(2):1003-13.
Title:	Performance comparison of three BRAF V600E detection methods in malignant melanoma and colorectal cancer specimens.
Author:	Loes, Inger Marie\|Immervoll, Heike\|Angelsen, Jon-Helge\|Horn, Arild\|Geisler, Jurgen\|Busch, Christian\|Lonning, Per Eystein\|Knappskog, Stian
PMID:	25318602

1076.
Journal:	Ann Surg Oncol. 2015 Apr;22(4):1226-1235.
Title:	Prognostic significance and molecular features of signet-ring cell and mucinous components in colorectal carcinoma.
Author:	Inamura, Kentaro\|Yamauchi, Mai\|Nishihara, Reiko\|Kim, Sun A\|Mima, Kosuke\|Sukawa, Yasutaka\|Li, Tingting\|Yasunari, Mika\|Zhang, Xuehong\|Wu, Kana\|Meyerhardt, Jeffrey A\|Fuchs, Charles S\|Harris, Curtis C\|Qian, Zhi Rong\|Ogino, Shuji
PMID:	25326395

1077.
Journal:	Tumour Biol. 2015 Feb;36(2):1091-7.
Title:	Combine MEK inhibition with PI3K/mTOR inhibition exert inhibitory tumor growth effect on KRAS and PIK3CA mutation CRC xenografts due to reduced expression of VEGF and matrix metallopeptidase-9.
Author:	E, Jifu\|Xing, Junjie\|Gong, Haifeng\|He, Jian\|Zhang, Wei
PMID:	25326806

1078.
Journal:	Virchows Arch. 2015 Jan;466(1):13-20.
Title:	Medullary carcinoma of the colon: can the undifferentiated be differentiated?
Author:	Fiehn, Anne-Marie Kanstrup\|Grauslund, Morten\|Glenthoj, Anders\|Melchior, Linea Cecilie\|Vainer, Ben\|Willemoe, Gro Linno
PMID:	25339302

1079.
Journal:	Genet Med. 2015 Jun;17(6):476-84.
Title:	Is it all Lynch syndrome?: An assessment of family history in individuals with mismatch repair-deficient tumors.
Author:	Dempsey, Katherine M\|Broaddus, Russell\|You, Y Nancy\|Noblin, Sarah Jane\|Mork, Maureen\|Fellman, Bryan\|Urbauer, Diana\|Daniels, Molly\|Lu, Karen
PMID:	25341111

1080.
Journal:	Ann Oncol. 2015 Jan;26(1):126-32.
Title:	Prognosis of stage II and III colon cancer treated with adjuvant 5-fluorouracil or FOLFIRI in relation to microsatellite status: results of the PETACC-3 trial.
Author:	Klingbiel, D\|Saridaki, Z\|Roth, A D\|Bosman, F T\|Delorenzi, M\|Tejpar, S
PMID:	25361982

1081.
Journal:	J Appl Genet. 2015 May;56(2):185-92.
Title:	Aberrant methylation of ERBB pathway genes in sporadic colorectal cancer.
Author:	Szmida, Elzbieta\|Karpinski, Pawel\|Leszczynski, Przemyslaw\|Sedziak, Tomasz\|Kielan, Wojciech\|Ostasiewicz, Pawel\|Sasiadek, Maria M
PMID:	25366420

1082.
Journal:	Zentralbl Chir. 2015 Dec;140(6):591-9.
Title:	[Colorectal Carcinoma with Suspected Lynch Syndrome: A Multidisciplinary Algorithm].
Author:	Schneider, R\|Schneider, C\|Buttner, R\|Reinacher-Schick, A\|Tannapfel, A\|Furst, A\|Ruschoff, J\|Jakobeit, C\|Royer-Pokora, B\|Moslein, G
PMID:	25372301

1083.
Journal:	Clin Transl Oncol. 2015 Apr;17(4):264-73.
Title:	Updated guidelines for biomarker testing in colorectal carcinoma: a national consensus of the Spanish Society of Pathology and the Spanish Society of Medical Oncology.
Author:	Garcia-Alfonso, P\|Garcia-Foncillas, J\|Salazar, R\|Perez-Segura, P\|Garcia-Carbonero, R\|Musulen-Palet, E\|Cuatrecasas, M\|Landolfi, S\|Ramon Y Cajal, S\|Navarro, S
PMID:	25373533

1084.
Journal:	J Clin Pathol. 2015 Jan;68(1):64-8.
Title:	Ion Torrent next-generation sequencing for routine identification of clinically relevant mutations in colorectal cancer patients.
Author:	Malapelle, Umberto\|Vigliar, Elena\|Sgariglia, Roberta\|Bellevicine, Claudio\|Colarossi, Lorenzo\|Vitale, Domenico\|Pallante, Pierlorenzo\|Troncone, Giancarlo
PMID:	25378536

1085.
Journal:	Cancer Res. 2015 Jan 1;75(1):216-29.
Title:	B-Raf inhibitors induce epithelial differentiation in BRAF-mutant colorectal cancer cells.
Author:	Herr, Ricarda\|Kohler, Martin\|Andrlova, Hana\|Weinberg, Florian\|Moller, Yvonne\|Halbach, Sebastian\|Lutz, Lisa\|Mastroianni, Justin\|Klose, Martin\|Bittermann, Nicola\|Kowar, Silke\|Zeiser, Robert\|Olayioye, Monilola A\|Lassmann, Silke\|Busch, Hauke\|Boerries, Melanie
PMID:	25381152

1086.
Journal:	J Gastroenterol. 2015 Jun;50(6):657-66.
Title:	Genome-wide linkage analysis and tumoral characterization reveal heterogeneity in familial colorectal cancer type X.
Author:	Sanchez-Tome, E\|Rivera, B\|Perea, J\|Pita, G\|Rueda, D\|Mercadillo, F\|Canal, A\|Gonzalez-Neira, A\|Benitez, J\|Urioste, M
PMID:	25381643

1087.
Journal:	Histopathology. 2015 Apr;66(5):715-25.
Title:	Tyrosine kinase receptor B (TrkB) expression in colorectal cancers highlights anoikis resistance as a survival mechanism of tumour budding cells.
Author:	Dawson, Heather\|Grundmann, Sandra\|Koelzer, Viktor H\|Galvan, Jose A\|Kirsch, Richard\|Karamitopoulou, Eva\|Lugli, Alessandro\|Inderbitzin, Daniel\|Zlobec, Inti
PMID:	25382057

1088.
Journal:	Virchows Arch. 2015 Jan;466(1):5-12.
Title:	Annexin A10 is a marker for the serrated pathway of colorectal carcinoma.
Author:	Sajanti, Sara A\|Vayrynen, Juha P\|Sirnio, Paivi\|Klintrup, Kai\|Makela, Jyrki\|Tuomisto, Anne\|Makinen, Markus J
PMID:	25395067

1089.
Journal:	Int J Cancer. 2015 Jun 15;136(12):2811-21.
Title:	MUC5AC hypomethylation is a predictor of microsatellite instability independently of clinical factors associated with colorectal cancer.
Author:	Renaud, Florence\|Vincent, Audrey\|Mariette, Christophe\|Crepin, Michel\|Stechly, Laurence\|Truant, Stephanie\|Copin, Marie-Christine\|Porchet, Nicole\|Leteurtre, Emmanuelle\|Van Seuningen, Isabelle\|Buisine, Marie-Pierre
PMID:	25403854

1090.
Journal:	Mol Carcinog. 2015 Dec;54(12):1786-95.
Title:	Rectal cancer profiling identifies distinct subtypes in India based on age at onset, genetic, epigenetic and clinicopathological characteristics.
Author:	Laskar, Ruhina Shirin\|Ghosh, Sankar Kumar\|Talukdar, Fazlur Rahman
PMID:	25418895

1091.
Journal:	Target Oncol. 2015 Sep;10(3):415-21.
Title:	Colorectal liver metastases are more often super wild type. Toward treatment based on metastatic site genotyping?
Author:	Allard, M A\|Saffroy, R\|de la Maisonneuve, P Bouvet\|Ricca, L\|Bosselut, N\|Hamelin, J\|Lecorche, E\|Bejarano, M A\|Innominato, P\|Sebagh, M\|Adam, R\|Morere, J F\|Lemoine, A
PMID:	25420993

1092.
Journal:	Horm Cancer. 2015 Feb;6(1):21-36.
Title:	BRAF inhibitors: experience in thyroid cancer and general review of toxicity.
Author:	Cabanillas, M E\|Patel, A\|Danysh, B P\|Dadu, R\|Kopetz, S\|Falchook, G
PMID:	25467940

1093.
Journal:	Ann Surg Oncol. 2015 Aug;22(8):2640-8.
Title:	Association of MicroRNA-31-5p with Clinical Efficacy of Anti-EGFR Therapy in Patients with Metastatic Colorectal Cancer.
Author:	Igarashi, Hisayoshi\|Kurihara, Hiroyoshi\|Mitsuhashi, Kei\|Ito, Miki\|Okuda, Hiroyuki\|Kanno, Shinichi\|Naito, Takafumi\|Yoshii, Shinji\|Takahashi, Hiroaki\|Kusumi, Takaya\|Hasegawa, Tadashi\|Sukawa, Yasutaka\|Adachi, Yasushi\|Okita, Kenji\|Hirata, Koichi\|Imamura, Yu\|B
PMID:	25472647

1094.
Journal:	Int J Surg. 2015 Jan;13:272-9.
Title:	MicroRNAs associated with initiation and progression of colonic polyp: a feasibility study.
Author:	Aslam, Muhammad Imran\|Hussein, Samir\|West, Kevin\|Singh, Baljit\|Jameson, John Stuart\|Pringle, James Howard
PMID:	25496852

1095.
Journal:	Oncogene. 2015 Sep 17;34(38):4914-27.
Title:	Oncogenic KRAS signalling promotes the Wnt/beta-catenin pathway through LRP6 in colorectal cancer.
Author:	Lemieux, E\|Cagnol, S\|Beaudry, K\|Carrier, J\|Rivard, N
PMID:	25500543

1096.
Journal:	Appl Immunohistochem Mol Morphol. 2015 Jul;23(6):438-43.
Title:	Immunohistochemical detection of the BRAF V600E mutant protein in colorectal neoplasms.
Author:	Vakiani, Efsevia\|Yaeger, Rona\|Brooke, Sylvester\|Zhou, Yi\|Klimstra, David S\|Shia, Jinru
PMID:	25517872

1097.
Journal:	Mol Cancer Ther. 2015 Feb;14(2):620-30.
Title:	IRS2 copy number gain, KRAS and BRAF mutation status as predictive biomarkers for response to the IGF-1R/IR inhibitor BMS-754807 in colorectal cancer cell lines.
Author:	Huang, Fei\|Chang, Han\|Greer, Ann\|Hillerman, Stephen\|Reeves, Karen A\|Hurlburt, Warren\|Cogswell, John\|Patel, Dharmesh\|Qi, Zhenhao\|Fairchild, Craig\|Ryseck, Rolf-Peter\|Wong, Tai W\|Finckenstein, Friedrich G\|Jackson, Jeffrey\|Carboni, Joan M
PMID:	25527633

1098.
Journal:	Dig Dis. 2015;33(1):28-37.
Title:	Serrated and non-serrated precursor lesions of colorectal cancer.
Author:	Langner, Cord
PMID:	25531494

1099.
Journal:	Pharmacogenomics J. 2015 Aug;15(4):354-62.
Title:	Distinct gene expression profiles of proximal and distal colorectal cancer: implications for cytotoxic and targeted therapy.
Author:	Maus, M K H\|Hanna, D L\|Stephens, C L\|Astrow, S H\|Yang, D\|Grimminger, P P\|Loupakis, F\|Hsiang, J H\|Zeger, G\|Wakatsuki, T\|Barzi, A\|Lenz, H-J
PMID:	25532759

1100.
Journal:	Dig Dis Sci. 2015 Mar;60(3):773-80.
Title:	How does the serrated polyp pathway alter CRC screening and surveillance?
Author:	Kahi, Charles J
PMID:	25556584

1101.
Journal:	Cancer. 2015 May 1;121(9):1395-404.
Title:	Prevalence of somatic mutl homolog 1 promoter hypermethylation in Lynch syndrome colorectal cancer.
Author:	Moreira, Leticia\|Munoz, Jenifer\|Cuatrecasas, Miriam\|Quintanilla, Isabel\|Leoz, Maria Liz\|Carballal, Sabela\|Ocana, Teresa\|Lopez-Ceron, Maria\|Pellise, Maria\|Castellvi-Bel, Sergi\|Jover, Rodrigo\|Andreu, Montserrat\|Carracedo, Angel\|Xicola, Rosa Maria\|Llor, Xavi
PMID:	25557234

1102.
Journal:	PLoS One. 2015 Jan 8;10(1):e0115672.
Title:	KRAS mutation analysis by PCR: a comparison of two methods.
Author:	Bolton, Louise\|Reiman, Anne\|Lucas, Katie\|Timms, Judith\|Cree, Ian A
PMID:	25568935

1103.
Journal:	Genet Med. 2015 Oct;17(10):765-73.
Title:	Economic evaluation of genetic screening for Lynch syndrome in Germany.
Author:	Severin, Franziska\|Stollenwerk, Bjorn\|Holinski-Feder, Elke\|Meyer, Elisabeth\|Heinemann, Volker\|Giessen-Jung, Clemens\|Rogowski, Wolf
PMID:	25569434

1104.
Journal:	Tumour Biol. 2015 May;36(5):3853-61.
Title:	Combined methylation of p16 and hMLH1 (CMETH2) discriminates a subpopulation with better prognosis in colorectal cancer patients with microsatellite instability tumors.
Author:	Veganzones, S\|Maestro, M L\|Rafael, S\|de la Orden, V\|Vidaurreta, M\|Mediero, B\|Espantaleon, M\|Cerdan, J\|Diaz-Rubio, E
PMID:	25576161

1105.
Journal:	Cancer Epidemiol Biomarkers Prev. 2015 Mar;24(3):512-519.
Title:	Association of the colorectal CpG island methylator phenotype with molecular features, risk factors, and family history.
Author:	Weisenberger, Daniel J\|Levine, A Joan\|Long, Tiffany I\|Buchanan, Daniel D\|Walters, Rhiannon\|Clendenning, Mark\|Rosty, Christophe\|Joshi, Amit D\|Stern, Mariana C\|LeMarchand, Loic\|Lindor, Noralane M\|Daftary, Darshana\|Gallinger, Steven\|Selander, Teresa\|Bapat, B
PMID:	25587051

1106.
Journal:	Clin Cancer Res. 2015 Mar 15;21(6):1313-20.
Title:	Pilot trial of combined BRAF and EGFR inhibition in BRAF-mutant metastatic colorectal cancer patients.
Author:	Yaeger, Rona\|Cercek, Andrea\|O'Reilly, Eileen M\|Reidy, Diane L\|Kemeny, Nancy\|Wolinsky, Tamar\|Capanu, Marinela\|Gollub, Marc J\|Rosen, Neal\|Berger, Michael F\|Lacouture, Mario E\|Vakiani, Efsevia\|Saltz, Leonard B
PMID:	25589621

1107.
Journal:	Cancer Res. 2015 Jan 15;75(2):245-9.
Title:	Colorectal cancer heterogeneity and targeted therapy: a case for molecular disease subtypes.
Author:	Linnekamp, Janneke F\|Wang, Xin\|Medema, Jan Paul\|Vermeulen, Louis
PMID:	25593032

1108.
Journal:	Am J Surg Pathol. 2015 Mar;39(3):313-7.
Title:	Sporadic microsatellite instability-high colon cancers rarely display immunohistochemical evidence of Wnt signaling activation.
Author:	Panarelli, Nicole C\|Vaughn, Cecily P\|Samowitz, Wade S\|Yantiss, Rhonda K
PMID:	25602793

1109.
Journal:	Mol Oncol. 2015 Apr;9(4):850-60.
Title:	Non-invasive sensitive detection of KRAS and BRAF mutation in circulating tumor cells of colorectal cancer patients.
Author:	Mohamed Suhaimi, Nur-Afidah\|Foong, Yu Miin\|Lee, Daniel Yoke San\|Phyo, Wai Min\|Cima, Igor\|Lee, Esther Xing Wei\|Goh, Wei Lin\|Lim, Wei-Yen\|Chia, Kee Seng\|Kong, Say Li\|Gong, Min\|Lim, Bing\|Hillmer, Axel M\|Koh, Poh Koon\|Ying, Jackie Y\|Tan, Min-Han
PMID:	25605225

1110.
Journal:	BMC Cancer. 2015 Jan 23;15:20.
Title:	Methylation and expression of the tumour suppressor, PRDM5, in colorectal cancer and polyp subgroups.
Author:	Bond, Catherine E\|Bettington, Mark L\|Pearson, Sally-Ann\|McKeone, Diane M\|Leggett, Barbara A\|Whitehall, Vicki L J
PMID:	25613750

1111.
Journal:	PLoS One. 2015 Jan 24;10(1):e0116753.
Title:	A pathway-centric survey of somatic mutations in Chinese patients with colorectal carcinomas.
Author:	Ling, Chao\|Wang, Lin\|Wang, Zheng\|Xu, Luming\|Sun, Lifang\|Yang, Hui\|Li, Wei-Dong\|Wang, Kai
PMID:	25617745

1112.
Journal:	Clin Cancer Res. 2015 May 1;21(9):2157-66.
Title:	Emergence of Multiple EGFR Extracellular Mutations during Cetuximab Treatment in Colorectal Cancer.
Author:	Arena, Sabrina\|Bellosillo, Beatriz\|Siravegna, Giulia\|Martinez, Alejandro\|Canadas, Israel\|Lazzari, Luca\|Ferruz, Noelia\|Russo, Mariangela\|Misale, Sandra\|Gonzalez, Iria\|Iglesias, Mar\|Gavilan, Elena\|Corti, Giorgio\|Hobor, Sebastijan\|Crisafulli, Giovanni\|Salido
PMID:	25623215

1113.
Journal:	World J Gastroenterol. 2015 Jan 21;21(3):926-34.
Title:	Deficient DNA mismatch repair is associated with favorable prognosis in Thai patients with sporadic colorectal cancer.
Author:	Korphaisarn, Krittiya\|Pongpaibul, Ananya\|Limwongse, Chanin\|Roothumnong, Ekkapong\|Klaisuban, Wipawi\|Nimmannit, Akarin\|Jinawath, Artit\|Akewanlop, Charuwan
PMID:	25624727

1114.
Journal:	Am J Cancer Res. 2014 Dec 15;5(1):72-86. eCollection 2015.
Title:	Dovitinib (TKI258), a multi-target angiokinase inhibitor, is effective regardless of KRAS or BRAF mutation status in colorectal cancer.
Author:	Lee, Choong-Kun\|Lee, Myung Eun\|Lee, Won Suk\|Kim, Jeong Min\|Park, Kyu Hyun\|Kim, Tae Soo\|Lee, Kang Young\|Ahn, Joong Bae\|Chung, Hyun Cheol\|Rha, Sun Young
PMID:	25628921

1115.
Journal:	World J Gastroenterol. 2015 Jan 28;21(4):1275-83.
Title:	Prognostic value of KRAS and BRAF mutations in curatively resected colorectal cancer.
Author:	Kadowaki, Shigenori\|Kakuta, Miho\|Takahashi, Shuhei\|Takahashi, Akemi\|Arai, Yoshiko\|Nishimura, Yoji\|Yatsuoka, Toshimasa\|Ooki, Akira\|Yamaguchi, Kensei\|Matsuo, Keitaro\|Muro, Kei\|Akagi, Kiwamu
PMID:	25632202

1116.
Journal:	Digestion. 2015;91(1):57-63.
Title:	Clinicopathological and molecular characteristics of serrated lesions in Japanese elderly patients.
Author:	Nosho, Katsuhiko\|Igarashi, Hisayoshi\|Ito, Miki\|Mitsuhashi, Kei\|Kurihara, Hiroyoshi\|Kanno, Shinichi\|Yoshii, Shinji\|Mikami, Masashi\|Takahashi, Hiroaki\|Kusumi, Takaya\|Hosokawa, Masao\|Sukawa, Yasutaka\|Adachi, Yasushi\|Hasegawa, Tadashi\|Okita, Kenji\|Hirata, Koi
PMID:	25632919

1117.
Journal:	BMC Med Genet. 2015 Jan 31;16:1.
Title:	The rare BRAF VK600-601E mutation as a possible indicator of poor prognosis in rectal carcinoma - a report of a case.
Author:	Mori, Yoshiko\|Nagasaka, Takeshi\|Mishima, Hideyuki\|Umeda, Yuzo\|Inada, Ryo\|Kishimoto, Hiroyuki\|Goel, Ajay\|Fujiwara, Toshiyoshi
PMID:	25636897

1118.
Journal:	BMC Cancer. 2015 Jan 31;15:26.
Title:	Development of a semi-conductor sequencing-based panel for genotyping of colon and lung cancer by the Onconetwork consortium.
Author:	Tops, Bastiaan B J\|Normanno, Nicola\|Kurth, Henriette\|Amato, Eliana\|Mafficini, Andrea\|Rieber, Nora\|Le Corre, Delphine\|Rachiglio, Anna Maria\|Reiman, Anne\|Sheils, Orla\|Noppen, Christoph\|Lacroix, Ludovic\|Cree, Ian A\|Scarpa, Aldo\|Ligtenberg, Marjolijn J L\|Laur
PMID:	25637035

1119.
Journal:	Sci Rep. 2015 Feb 2;5:8065.
Title:	Concordant analysis of KRAS, BRAF, PIK3CA mutations, and PTEN expression between primary colorectal cancer and matched metastases.
Author:	Mao, Chen\|Wu, Xin-Yin\|Yang, Zu-Yao\|Threapleton, Diane Erin\|Yuan, Jin-Qiu\|Yu, Yuan-Yuan\|Tang, Jin-Ling
PMID:	25639985

1120.
Journal:	Tumour Biol. 2015 Jun;36(6):4661-70.
Title:	Association of HPV with genetic and epigenetic alterations in colorectal adenocarcinoma from Indian population.
Author:	Laskar, Ruhina S\|Talukdar, Fazlur R\|Choudhury, Javed H\|Singh, Seram Anil\|Kundu, Sharbadeb\|Dhar, Bishal\|Mondal, Rosy\|Ghosh, Sankar Kumar
PMID:	25647260

1121.
Journal:	Oncologist. 2015 Mar;20(3):257-62.
Title:	External quality assessment unravels interlaboratory differences in quality of RAS testing for anti-EGFR therapy in colorectal cancer.
Author:	Tack, Veronique\|Ligtenberg, Marjolijn J L\|Tembuyser, Lien\|Normanno, Nicola\|Vander Borght, Sara\|Han van Krieken, J\|Dequeker, Elisabeth M C
PMID:	25657200

1122.
Journal:	World J Gastroenterol. 2015 Feb 7;21(5):1457-67.
Title:	Loss of CDX2 expression is associated with poor prognosis in colorectal cancer patients.
Author:	Bae, Jeong Mo\|Lee, Tae Hun\|Cho, Nam-Yun\|Kim, Tae-You\|Kang, Gyeong Hoon
PMID:	25663765

1123.
Journal:	World J Gastroenterol. 2015 Feb 7;21(5):1595-605.
Title:	KRAS and BRAF gene mutations and DNA mismatch repair status in Chinese colorectal carcinoma patients.
Author:	Ye, Ju-Xiang\|Liu, Yan\|Qin, Yun\|Zhong, Hao-Hao\|Yi, Wei-Ning\|Shi, Xue-Ying
PMID:	25663779

1124.
Journal:	Oncol Lett. 2015 Mar;9(3):1432-1438.
Title:	EGFR methylation and outcome of patients with advanced colorectal cancer treated with cetuximab.
Author:	Chiadini, Elisa\|Scarpi, Emanuela\|Passardi, Alessandro\|Calistri, Daniele\|Valgiusti, Martina\|Saragoni, Luca\|Zoli, Wainer\|Amadori, Dino\|Ulivi, Paola
PMID:	25663927

1125.
Journal:	Clin Colorectal Cancer. 2015 Jun;14(2):91-8.
Title:	FOLFOX4 Plus Cetuximab for Patients With Previously Untreated Metastatic Colorectal Cancer According to Tumor RAS and BRAF Mutation Status: Updated Analysis of the CECOG/CORE 1.2.002 Study.
Author:	Kaczirek, Klaus\|Ciuleanu, Tudor E\|Vrbanec, Damir\|Marton, Erika\|Messinger, Diethelm\|Liegl-Atzwanger, Bernadette\|Wrba, Fritz\|Knittelfelder, Regina\|Lindner, Elisabeth\|Zielinski, Christoph C\|Streubel, Berthold\|Brodowicz, Thomas
PMID:	25666295

1126.
Journal:	Eur J Cancer. 2015 Mar;51(5):587-94.
Title:	Predictive role of BRAF mutations in patients with advanced colorectal cancer receiving cetuximab and panitumumab: a meta-analysis.
Author:	Pietrantonio, Filippo\|Petrelli, Fausto\|Coinu, Andrea\|Di Bartolomeo, Maria\|Borgonovo, Karen\|Maggi, Claudia\|Cabiddu, Mary\|Iacovelli, Roberto\|Bossi, Ilaria\|Lonati, Veronica\|Ghilardi, Mara\|de Braud, Filippo\|Barni, Sandro
PMID:	25673558

1127.
Journal:	Cancer Discov. 2015 Apr;5(4):358-67.
Title:	Clinical Acquired Resistance to RAF Inhibitor Combinations in BRAF-Mutant Colorectal Cancer through MAPK Pathway Alterations.
Author:	Ahronian, Leanne G\|Sennott, Erin M\|Van Allen, Eliezer M\|Wagle, Nikhil\|Kwak, Eunice L\|Faris, Jason E\|Godfrey, Jason T\|Nishimura, Koki\|Lynch, Kerry D\|Mermel, Craig H\|Lockerman, Elizabeth L\|Kalsy, Anuj\|Gurski, Joseph M Jr\|Bahl, Samira\|Anderka, Kristin\|Green,
PMID:	25673644

1128.
Journal:	Hum Pathol. 2015 Apr;46(4):507-13.
Title:	Novel molecular insights from routine genotyping of colorectal carcinomas.
Author:	Stachler, Matthew D\|Rinehart, Elizabeth\|Lindeman, Neal\|Odze, Robert\|Srivastava, Amitabh
PMID:	25683705

1129.
Journal:	J Cancer Epidemiol. 2015;2015:643020.
Title:	Colorectal cancer in iran: molecular epidemiology and screening strategies.
Author:	Dolatkhah, Roya\|Somi, Mohammad Hossein\|Bonyadi, Mortaza Jabbarpour\|Asvadi Kermani, Iraj\|Farassati, Faris\|Dastgiri, Saeed
PMID:	25685149

1130.
Journal:	Br J Cancer. 2015 Mar 17;112(6):1088-97.
Title:	Cytokine profile and prognostic significance of high neutrophil-lymphocyte ratio in colorectal cancer.
Author:	Chen, Z-Y\|Raghav, K\|Lieu, C H\|Jiang, Z-Q\|Eng, C\|Vauthey, J-N\|Chang, G J\|Qiao, W\|Morris, J\|Hong, D\|Hoff, P\|Tran, H\|Menter, D G\|Heymach, J\|Overman, M\|Kopetz, S
PMID:	25688736

1131.
Journal:	Br J Cancer. 2015 Feb 17;112(4):720-8.
Title:	KRAS and BRAF mutations are prognostic biomarkers in patients undergoing lung metastasectomy of colorectal cancer.
Author:	Renaud, S\|Romain, B\|Falcoz, P-E\|Olland, A\|Santelmo, N\|Brigand, C\|Rohr, S\|Guenot, D\|Massard, G
PMID:	25688918

1132.
Journal:	Am J Clin Pathol. 2015 Mar;143(3):374-84.
Title:	Left-sided early-onset vs late-onset colorectal carcinoma: histologic, clinical, and molecular differences.
Author:	Pilozzi, Emanuela\|Maresca, Carmen\|Duranti, Enrico\|Giustiniani, Maria Cristina\|Catalanotto, Caterina\|Lucarelli, Marco\|Cogoni, Carlo\|Ferri, Mario\|Ruco, Luigi\|Zardo, Giuseppe
PMID:	25696795

1133.
Journal:	Front Oncol. 2015 Feb 2;5:13.
Title:	Implications of epithelial-mesenchymal plasticity for heterogeneity in colorectal cancer.
Author:	Pereira, Lloyd\|Mariadason, John M\|Hannan, Ross D\|Dhillon, Amardeep S
PMID:	25699236

1134.
Journal:	Arch Toxicol. 2015 Jun;89(6):899-921.
Title:	Microsatellite instability: an update.
Author:	Yamamoto, Hiroyuki\|Imai, Kohzoh
PMID:	25701956

1135.
Journal:	Int J Cancer. 2015 Sep 15;137(6):1467-74.
Title:	Circulating tumor cells as a longitudinal biomarker in patients with advanced chemorefractory, RAS-BRAF wild-type colorectal cancer receiving cetuximab or panitumumab.
Author:	Musella, Valeria\|Pietrantonio, Filippo\|Di Buduo, Eleonora\|Iacovelli, Roberto\|Martinetti, Antonia\|Sottotetti, Elisa\|Bossi, Ilaria\|Maggi, Claudia\|Di Bartolomeo, Maria\|de Braud, Filippo\|Daidone, Maria Grazia\|Cappelletti, Vera
PMID:	25704501

1136.
Journal:	APMIS. 2015 Apr;123(4):298-304.
Title:	Hyperplastic polyps of the colon and rectum - reclassification, BRAF and KRAS status in index polyps and subsequent colorectal carcinoma.
Author:	Janjua, Huma Gul Rehana\|Hogdall, Estrid\|Linnemann, Dorte
PMID:	25708741

1137.
Journal:	Cancer Res. 2015 Apr 15;75(8):1560-6.
Title:	Evaluating patient-derived colorectal cancer xenografts as preclinical models by comparison with patient clinical data.
Author:	Nunes, Manoel\|Vrignaud, Patricia\|Vacher, Sophie\|Richon, Sophie\|Lievre, Astrid\|Cacheux, Wulfran\|Weiswald, Louis-Bastien\|Massonnet, Gerald\|Chateau-Joubert, Sophie\|Nicolas, Andre\|Dib, Colette\|Zhang, Weidong\|Watters, James\|Bergstrom, Donald\|Roman-Roman, Sergi
PMID:	25712343

1138.
Journal:	Cancer. 2015 Jun 1;121(11):1762-71.
Title:	Prevalence of Lynch syndrome in a Middle Eastern population with colorectal cancer.
Author:	Siraj, Abdul K\|Prabhakaran, Sarita\|Bavi, Prashant\|Bu, Rong\|Beg, Shaham\|Hazmi, Mohsen Al\|Al-Rasheed, Maha\|Al-Assiri, Mohammed\|Sairafi, Rami\|Al-Dayel, Fouad\|Al-Sanea, Nasser\|Uddin, Shahab\|Al-Kuraya, Khawla S
PMID:	25712738

1139.
Journal:	Mol Cancer Res. 2015 Jun;13(6):1003-8.
Title:	AKT1 E17K in Colorectal Carcinoma Is Associated with BRAF V600E but Not MSI-H Status: A Clinicopathologic Comparison to PIK3CA Helical and Kinase Domain Mutants.
Author:	Hechtman, Jaclyn F\|Sadowska, Justyna\|Huse, Jason T\|Borsu, Laetitia\|Yaeger, Rona\|Shia, Jinru\|Vakiani, Efsevia\|Ladanyi, Marc\|Arcila, Maria E
PMID:	25714871

1140.
Journal:	PLoS One. 2015 Mar 3;10(3):e0118612.
Title:	Genetic characteristics of mitochondrial DNA was associated with colorectal carcinogenesis and its prognosis.
Author:	Lee, Jae-Ho\|Hwang, Ilseon\|Kang, Yu-Na\|Choi, In-Jang\|Kim, Dae-Kwang
PMID:	25734426

1141.
Journal:	Mol Cancer. 2015 Feb 14;14:38.
Title:	High MACC1 expression in combination with mutated KRAS G13 indicates poor survival of colorectal cancer patients.
Author:	Ilm, Katharina\|Kemmner, Wolfgang\|Osterland, Marc\|Burock, Susen\|Koch, Gudrun\|Herrmann, Pia\|Schlag, Peter M\|Stein, Ulrike
PMID:	25742883

1142.
Journal:	Semin Diagn Pathol. 2015 Sep;32(5):400-8.
Title:	BRAF V600E mutation-specific antibody: A review.
Author:	Ritterhouse, Lauren L\|Barletta, Justine A
PMID:	25744437

1143.
Journal:	Ann Coloproctol. 2015 Feb;31(1):1-2.
Title:	Does BRAF Mutation and Extracellular Signal Regulated Kinase Expression in Patients With Colorectal Cancer Have Any Prognostic Significance?
Author:	Baek, Moo Jun
PMID:	25745617

1144.
Journal:	Ann Coloproctol. 2015 Feb;31(1):9-15.
Title:	Clinicopathologic Significance of BRAF Mutation and Extracellular Signal Regulated Kinase 1/2 Expression in Patients With a Colorectal Adenocarcinoma.
Author:	Kim, Hyung Ook\|Kim, Beom Gyu\|Cha, Seong Jae\|Park, Yong Gum\|Lee, Tae Jin
PMID:	25745621

1145.
Journal:	Mol Ther Nucleic Acids. 2015 Mar 10;4:e231.
Title:	Concurrent Targeting of KRAS and AKT by MiR-4689 Is a Novel Treatment Against Mutant KRAS Colorectal Cancer.
Author:	Hiraki, Masayuki\|Nishimura, Junichi\|Takahashi, Hidekazu\|Wu, Xin\|Takahashi, Yusuke\|Miyo, Masaaki\|Nishida, Naohiro\|Uemura, Mamoru\|Hata, Taishi\|Takemasa, Ichiro\|Mizushima, Tsunekazu\|Soh, Jae-Won\|Doki, Yuichiro\|Mori, Masaki\|Yamamoto, Hirofumi
PMID:	25756961

1146.
Journal:	Curr Opin Oncol. 2015 May;27(3):276-81.
Title:	B-type proto-oncogene-mutated tumors of colon cancer: promising therapeutic approaches.
Author:	Temraz, Sally\|Alameddine, Raafat\|Shamseddine, Ali
PMID:	25774859

1147.
Journal:	Pathologe. 2015 Mar;36(2):137-44.
Title:	[Molecular pathology of colorectal cancer].
Author:	Neumann, J H L\|Jung, A\|Kirchner, T
PMID:	25777075

1148.
Journal:	Sci Rep. 2015 Mar 18;5:9211.
Title:	Detection of BRAF mutation in Chinese tumor patients using a highly sensitive antibody immunohistochemistry assay.
Author:	Qiu, Tian\|Lu, Haizhen\|Guo, Lei\|Huang, Wenting\|Ling, Yun\|Shan, Ling\|Li, Wenbin\|Ying, Jianming\|Lv, Ning
PMID:	25784606

1149.
Journal:	Front Oncol. 2015 Mar 3;5:54.
Title:	Current Understanding of BRAF Alterations in Diagnosis, Prognosis, and Therapeutic Targeting in Pediatric Low-Grade Gliomas.
Author:	Penman, Catherine Louise\|Faulkner, Claire\|Lowis, Stephen P\|Kurian, Kathreena M
PMID:	25785246

1150.
Journal:	Am J Surg Pathol. 2015 Aug;39(8):1140-7.
Title:	Distinctive Spatiotemporal Stability of Somatic Mutations in Metastasized Microsatellite-stable Colorectal Cancer.
Author:	Jesinghaus, Moritz\|Wolf, Thomas\|Pfarr, Nicole\|Muckenhuber, Alexander\|Ahadova, Aysel\|Warth, Arne\|Goeppert, Benjamin\|Sers, Christine\|Kloor, Matthias\|Endris, Volker\|Stenzinger, Albrecht\|Weichert, Wilko
PMID:	25786087

1151.
Journal:	J Invest Dermatol. 2015 Jul;135(7):1863-1872.
Title:	MITF Modulates Therapeutic Resistance through EGFR Signaling.
Author:	Ji, Zhenyu\|Erin Chen, Yiyin\|Kumar, Raj\|Taylor, Michael\|Jenny Njauw, Ching-Ni\|Miao, Benchun\|Frederick, Dennie T\|Wargo, Jennifer A\|Flaherty, Keith T\|Jonsson, Goran\|Tsao, Hensin
PMID:	25789707

1152.
Journal:	J Natl Cancer Inst. 2015 Mar 20;107(4). pii: djv005.
Title:	Comparative effectiveness of screening strategies for Lynch syndrome.
Author:	Barzi, Afsaneh\|Sadeghi, Sarmad\|Kattan, Michael W\|Meropol, Neal J
PMID:	25794514

1153.
Journal:	Am J Pathol. 2015 Apr;185(4):1135-44.
Title:	Methionine adenosyltransferase 2B-GIT1 complex serves as a scaffold to regulate Ras/Raf/MEK1/2 activity in human liver and colon cancer cells.
Author:	Peng, Hui\|Li, Tony W H\|Yang, Heping\|Moyer, Mary P\|Mato, Jose M\|Lu, Shelly C
PMID:	25794709

1154.
Journal:	Oncotarget. 2015 Mar 30;6(9):7209-20.
Title:	Association of Fusobacterium species in pancreatic cancer tissues with molecular features and prognosis.
Author:	Mitsuhashi, Kei\|Nosho, Katsuhiko\|Sukawa, Yasutaka\|Matsunaga, Yasutaka\|Ito, Miki\|Kurihara, Hiroyoshi\|Kanno, Shinichi\|Igarashi, Hisayoshi\|Naito, Takafumi\|Adachi, Yasushi\|Tachibana, Mami\|Tanuma, Tokuma\|Maguchi, Hiroyuki\|Shinohara, Toshiya\|Hasegawa, Tadashi\|I
PMID:	25797243

1155.
Journal:	Transl Res. 2015 Aug;166(2):207-17.
Title:	Active immunosurveillance in the tumor microenvironment of colorectal cancer is associated with low frequency tumor budding and improved outcome.
Author:	Koelzer, Viktor H\|Dawson, Heather\|Andersson, Emilia\|Karamitopoulou, Eva\|Masucci, Giuseppe V\|Lugli, Alessandro\|Zlobec, Inti
PMID:	25797890

1156.
Journal:	J Natl Cancer Inst. 2015 Mar 25;107(4). pii: djv007.
Title:	Marine omega-3 polyunsaturated fatty acids and risk of colorectal cancer according to microsatellite instability.
Author:	Song, Mingyang\|Nishihara, Reiko\|Wu, Kana\|Qian, Zhi Rong\|Kim, Sun A\|Sukawa, Yasutaka\|Mima, Kosuke\|Inamura, Kentaro\|Masuda, Atsuhiro\|Yang, Juhong\|Fuchs, Charles S\|Giovannucci, Edward L\|Ogino, Shuji\|Chan, Andrew T
PMID:	25810492

1157.
Journal:	Clin Cancer Res. 2015 Jul 15;21(14):3230-3240.
Title:	HDAC Inhibition Overcomes Acute Resistance to MEK Inhibition in BRAF-Mutant Colorectal Cancer by Downregulation of c-FLIPL.
Author:	Carson, Robbie\|Celtikci, Basak\|Fenning, Cathy\|Javadi, Arman\|Crawford, Nyree\|Carbonell, Lucia Perez\|Lawler, Mark\|Longley, Daniel B\|Johnston, Patrick G\|Van Schaeybroeck, Sandra
PMID:	25813020

1158.
Journal:	Mol Med Rep. 2015 Jul;12(1):1219-24.
Title:	Identification of KRAS and PIK3CA but not BRAF mutations in patients with gastric cancer.
Author:	Lu, Weipeng\|Wei, Hong\|Li, Mei\|Wang, Hai\|Liu, Lina\|Zhang, Qiuping\|Liu, Lisha\|Lu, Shen
PMID:	25815786

1159.
Journal:	Clin Cancer Res. 2015 Jul 1;21(13):2975-83.
Title:	Primary and Acquired Resistance of Colorectal Cancer to Anti-EGFR Monoclonal Antibody Can Be Overcome by Combined Treatment of Regorafenib with Cetuximab.
Author:	Napolitano, Stefania\|Martini, Giulia\|Rinaldi, Barbara\|Martinelli, Erika\|Donniacuo, Maria\|Berrino, Liberato\|Vitagliano, Donata\|Morgillo, Floriana\|Barra, Giusy\|De Palma, Raffaele\|Merolla, Francesco\|Ciardiello, Fortunato\|Troiani, Teresa
PMID:	25838391

1160.
Journal:	Dig Dis Sci. 2015 Aug;60(8):2477-87.
Title:	Systemic Analysis of Predictive Biomarkers for Recurrence in Colorectal Cancer Patients Treated with Curative Surgery.
Author:	Mori, Koichiro\|Toiyama, Yuji\|Saigusa, Susumu\|Fujikawa, Hiroyuki\|Hiro, Junichiro\|Kobayashi, Minako\|Ohi, Masaki\|Araki, Toshimitsu\|Inoue, Yasuhiro\|Tanaka, Koji\|Mohri, Yasuhiko\|Kusunoki, Masato
PMID:	25840921

1161.
Journal:	Adv Anat Pathol. 2015 May;22(3):217-24.
Title:	Selected case from the Arkadi M. Rywlin International Pathology Slide Club: carcinoma of the transverse colon in a young girl.
Author:	Galliani, Carlos A\|Sanchez, Irene C\|D'Errico, Maria M\|Bisceglia, Michele
PMID:	25844680

1162.
Journal:	Cancer Discov. 2015 Apr;5(4):348-50.
Title:	Old Habits Die Hard: Addiction of BRAF-Mutant Cancer Cells to MAP Kinase Signaling.
Author:	Meador, Catherine B\|Pao, William
PMID:	25847954

1163.
Journal:	Ann Oncol. 2015 Aug;26(8):1710-4.
Title:	Heterogeneity of KRAS, NRAS, BRAF and PIK3CA mutations in metastatic colorectal cancer and potential effects on therapy in the CAPRI GOIM trial.
Author:	Normanno, N\|Rachiglio, A M\|Lambiase, M\|Martinelli, E\|Fenizia, F\|Esposito, C\|Roma, C\|Troiani, T\|Rizzi, D\|Tatangelo, F\|Botti, G\|Maiello, E\|Colucci, G\|Ciardiello, F
PMID:	25851630

1164.
Journal:	Pigment Cell Melanoma Res. 2015 Jul;28(4):417-30.
Title:	The broad-spectrum receptor tyrosine kinase inhibitor dovitinib suppresses growth of BRAF-mutant melanoma cells in combination with other signaling pathway inhibitors.
Author:	Langdon, Casey G\|Held, Matthew A\|Platt, James T\|Meeth, Katrina\|Iyidogan, Pinar\|Mamillapalli, Ramanaiah\|Koo, Andrew B\|Klein, Michael\|Liu, Zongzhi\|Bosenberg, Marcus W\|Stern, David F
PMID:	25854919

1165.
Journal:	Cancer Sci. 2015 Jun;106(6):692-9.
Title:	Antitumor activity of the MEK inhibitor trametinib on intestinal polyp formation in Apc(Delta716) mice involves stromal COX-2.
Author:	Fujishita, Teruaki\|Kajino-Sakamoto, Rie\|Kojima, Yasushi\|Taketo, Makoto Mark\|Aoki, Masahiro
PMID:	25855137

1166.
Journal:	Anticancer Res. 2015 Apr;35(4):2345-50.
Title:	BRAF V600E mutation in colorectal cancer is associated with right-sided tumours and iron deficiency anaemia.
Author:	Sideris, Michail\|Adams, Katie\|Moorhead, Jane\|Diaz-Cano, Salvador\|Bjarnason, Ingvar\|Papagrigoriadis, Savvas
PMID:	25862899

1167.
Journal:	Clin Biochem. 2015 Sep;48(13-14):908-10.
Title:	Validation of the Ion Torrent PGM sequencing for the prospective routine molecular diagnostic of colorectal cancer.
Author:	Belardinilli, Francesca\|Capalbo, Carlo\|Buffone, Amelia\|Petroni, Marialaura\|Colicchia, Valeria\|Ferraro, Sergio\|Zani, Massimo\|Nicolussi, Arianna\|D'Inzeo, Sonia\|Coppa, Anna\|Screpanti, Isabella\|Gulino, Alberto\|Giannini, Giuseppe
PMID:	25872148

1168.
Journal:	BMC Cancer. 2015 Mar 14;15:125.
Title:	Microsatellite instability and mutations in BRAF and KRAS are significant predictors of disseminated disease in colon cancer.
Author:	Birgisson, Helgi\|Edlund, Karolina\|Wallin, Ulrik\|Pahlman, Lars\|Kultima, Hanna Goransson\|Mayrhofer, Markus\|Micke, Patrick\|Isaksson, Anders\|Botling, Johan\|Glimelius, Bengt\|Sundstrom, Magnus
PMID:	25884297

1169.
Journal:	BMC Cancer. 2015 Mar 21;15:160.
Title:	Heterogeneity analysis of Metastasis Associated in Colon Cancer 1 (MACC1) for survival prognosis of colorectal cancer patients: a retrospective cohort study.
Author:	Koelzer, Viktor H\|Herrmann, Pia\|Zlobec, Inti\|Karamitopoulou, Eva\|Lugli, Alessandro\|Stein, Ulrike
PMID:	25884643

1170.
Journal:	BMC Cancer. 2015 Apr 8;15:240.
Title:	HGUE-C-1 is an atypical and novel colon carcinoma cell line.
Author:	Grasso, Silvina\|Martinez-Lacaci, Isabel\|Barbera, Victor Manuel\|Castillejo, Adela\|Soto, Jose Luis\|Gallego-Plazas, Javier\|Lopez-Riquelme, Natividad\|Garcia-Morales, Pilar\|Mata-Balaguer, Trinidad\|Ferragut, Jose Antonio\|Saceda, Miguel
PMID:	25885658

1171.
Journal:	Pathol Res Pract. 2015 Jul;211(7):521-7.
Title:	Russian study of morphological prognostic factors characterization in BRAF-mutant cutaneous melanoma.
Author:	Aksenenko, M B\|Kirichenko, A K\|Ruksha, T G
PMID:	25888143

1172.
Journal:	J Transl Med. 2015 Feb 12;13:57.
Title:	Tumour pharmacodynamics and circulating cell free DNA in patients with refractory colorectal carcinoma treated with regorafenib.
Author:	Wong, Andrea Li Ann\|Lim, Joline Si Jing\|Sinha, Arvind\|Gopinathan, Anil\|Lim, Robert\|Tan, Chee-Seng\|Soh, Thomas\|Venkatesh, Sudhakar\|Titin, Christina\|Sapari, Nur Sabrina\|Lee, Soo-Chin\|Yong, Wei-Peng\|Tan, David Shao Ping\|Pang, Brendan\|Wang, Ting-Ting\|Zee, Yin
PMID:	25889309

1173.
Journal:	Cancer Prev Res (Phila). 2015 Jul;8(7):614-9.
Title:	TFF2-CXCR4 Axis Is Associated with BRAF V600E Colon Cancer.
Author:	Gala, Manish K\|Austin, Thomas\|Ogino, Shuji\|Chan, Andrew T
PMID:	25899003

1174.
Journal:	PLoS One. 2015 Apr 22;10(4):e0123902.
Title:	Mutational analysis of circulating tumor cells from colorectal cancer patients and correlation with primary tumor tissue.
Author:	Lyberopoulou, Anna\|Aravantinos, Gerasimos\|Efstathopoulos, Efstathios P\|Nikiteas, Nikolaos\|Bouziotis, Penelope\|Isaakidou, Athina\|Papalois, Apostolos\|Marinos, Evangelos\|Gazouli, Maria
PMID:	25902072

1175.
Journal:	BMC Cancer. 2015 Apr 25;15:313.
Title:	A model-based assessment of the cost-utility of strategies to identify Lynch syndrome in early-onset colorectal cancer patients.
Author:	Snowsill, Tristan\|Huxley, Nicola\|Hoyle, Martin\|Jones-Hughes, Tracey\|Coelho, Helen\|Cooper, Chris\|Frayling, Ian\|Hyde, Chris
PMID:	25910169

1176.
Journal:	J Clin Oncol. 2015 Jun 1;33(16):1787-96.
Title:	Personalizing colon cancer adjuvant therapy: selecting optimal treatments for individual patients.
Author:	Dienstmann, Rodrigo\|Salazar, Ramon\|Tabernero, Josep
PMID:	25918287

1177.
Journal:	Br J Cancer. 2015 Apr 28;112(9):1480-90.
Title:	MicroRNA-224 is associated with colorectal cancer progression and response to 5-fluorouracil-based chemotherapy by KRAS-dependent and -independent mechanisms.
Author:	Amankwatia, E B\|Chakravarty, P\|Carey, F A\|Weidlich, S\|Steele, R J C\|Munro, A J\|Wolf, C R\|Smith, G
PMID:	25919696

1178.
Journal:	Acta Oncol. 2015 Nov;54(10):1747-53.
Title:	Neoadjuvant chemotherapy in locally advanced colon cancer. A phase II trial.
Author:	Jakobsen, Anders\|Andersen, Fahimeh\|Fischer, Anders\|Jensen, Lars H\|Jorgensen, Jens C R\|Larsen, Ole\|Lindebjerg, Jan\|Ploen, John\|Rafaelsen, Soren R\|Vilandt, Jesper
PMID:	25920359

1179.
Journal:	Digestion. 2015;91(4):286-93.
Title:	Tumor and Patient Characteristics of Individuals with Mismatch Repair Deficient Colorectal Cancer.
Author:	Waldmann, Elisabeth\|Ferlitsch, Monika\|Binder, Nicolas\|Sellner, Franz\|Karner, Josef\|Heinisch, Birgit\|Klimpfinger, Martin\|Trauner, Michael
PMID:	25924923

1180.
Journal:	Digestion. 2015;91(4):294-302.
Title:	Established and Potential Predictive Biomarkers in Gastrointestinal Cancer--c-Kit, Her2, Ras and Beyond.
Author:	Koch, Christine\|Trojan, Joerg
PMID:	25924988

1181.
Journal:	Nat Commun. 2015 Apr 30;6:7002.
Title:	The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets.
Author:	Medico, Enzo\|Russo, Mariangela\|Picco, Gabriele\|Cancelliere, Carlotta\|Valtorta, Emanuele\|Corti, Giorgio\|Buscarino, Michela\|Isella, Claudio\|Lamba, Simona\|Martinoglio, Barbara\|Veronese, Silvio\|Siena, Salvatore\|Sartore-Bianchi, Andrea\|Beccuti, Marco\|Mottolese
PMID:	25926053

1182.
Journal:	PLoS One. 2015 Apr 30;10(4):e0122679.
Title:	Downregulated Long Noncoding RNA BANCR Promotes the Proliferation of Colorectal Cancer Cells via Downregualtion of p21 Expression.
Author:	Shi, Yongguo\|Liu, Yangchen\|Wang, Jirong\|Jie, Ding\|Yun, Tian\|Li, Wang\|Yan, Lin\|Wang, Keming\|Feng, Jifeng
PMID:	25928067

1183.
Journal:	BMC Cancer. 2015 May 1;15:340.
Title:	Colorectal carcinomas with KRAS codon 12 mutation are associated with more advanced tumor stages.
Author:	Li, Wenbin\|Qiu, Tian\|Zhi, Wenxue\|Shi, Susheng\|Zou, Shuangmei\|Ling, Yun\|Shan, Ling\|Ying, Jianming\|Lu, Ning
PMID:	25929517

1184.
Journal:	Ecancermedicalscience. 2015 Apr 9;9:520.
Title:	Biology of colorectal cancer.
Author:	Arvelo, Francisco\|Sojo, Felipe\|Cotte, Carlos
PMID:	25932044

1185.
Journal:	Ecancermedicalscience. 2015 Apr 15;9:522.
Title:	Cancer mutation screening: Comparison of high-resolution melt analysis between two platforms.
Author:	Ebili, Henry O\|Ilyas, Mohammad
PMID:	25932046

1186.
Journal:	Int J Oncol. 2015 Jul;47(1):97-105.
Title:	A novel approach to detect KRAS/BRAF mutation for colon cancer: Highly sensitive simultaneous detection of mutations and simple pre-treatment without DNA extraction.
Author:	Suzuki, Shun-Ichi\|Matsusaka, Satoshi\|Hirai, Mitsuharu\|Shibata, Harumi\|Takagi, Koichi\|Mizunuma, Nobuyuki\|Hatake, Kiyohiko
PMID:	25936694

1187.
Journal:	J Transl Med. 2015 May 7;13:140.
Title:	Prospective study of a molecular selection profile for RAS wild type colorectal cancer patients receiving irinotecan-cetuximab.
Author:	Giampieri, Riccardo\|Mandolesi, Alessandra\|Abouelkhair, Khaled M\|Loretelli, Cristian\|Del Prete, Michela\|Faloppi, Luca\|Maristella, Bianconi\|Ibrahim, Ezzeldin M\|Scarpelli, Marina\|Cascinu, Stefano\|Scartozzi, Mario
PMID:	25943333

1188.
Journal:	Cancer Immunol Res. 2015 Sep;3(9):1052-62.
Title:	Identification and Characterization of MEDI4736, an Antagonistic Anti-PD-L1 Monoclonal Antibody.
Author:	Stewart, Ross\|Morrow, Michelle\|Hammond, Scott A\|Mulgrew, Kathy\|Marcus, Danielle\|Poon, Edmund\|Watkins, Amanda\|Mullins, Stefanie\|Chodorge, Matthieu\|Andrews, John\|Bannister, David\|Dick, Emily\|Crawford, Nicola\|Parmentier, Julie\|Alimzhanov, Marat\|Babcook, John
PMID:	25943534

1189.
Journal:	Oncotarget. 2015 Jun 20;6(17):15681-9.
Title:	RAS testing in metastatic colorectal cancer: excellent reproducibility amongst 17 Dutch pathology centers.
Author:	Boleij, Annemarie\|Tops, Bastiaan B J\|Rombout, Paul D M\|Dequeker, Elizabeth M\|Ligtenberg, Marjolijn J L\|van Krieken, J Han
PMID:	25944693

1190.
Journal:	PLoS One. 2015 May 8;10(5):e0121891.
Title:	Extended RAS and BRAF Mutation Analysis Using Next-Generation Sequencing.
Author:	Sakai, Kazuko\|Tsurutani, Junji\|Yamanaka, Takeharu\|Yoneshige, Azusa\|Ito, Akihiko\|Togashi, Yosuke\|De Velasco, Marco A\|Terashima, Masato\|Fujita, Yoshihiko\|Tomida, Shuta\|Tamura, Takao\|Nakagawa, Kazuhiko\|Nishio, Kazuto
PMID:	25954997

1191.
Journal:	BMC Cancer. 2015 May 10;15:384.
Title:	Randomized phase III clinical trial comparing the combination of capecitabine and oxaliplatin (CAPOX) with the combination of 5-fluorouracil, leucovorin and oxaliplatin (modified FOLFOX6) as adjuvant therapy in patients with operated high-risk stage II or
Author:	Pectasides, Dimitrios\|Karavasilis, Vasilios\|Papaxoinis, George\|Gourgioti, Georgia\|Makatsoris, Thomas\|Raptou, Georgia\|Vrettou, Eleni\|Sgouros, Joseph\|Samantas, Epaminontas\|Basdanis, George\|Papakostas, Pavlos\|Bafaloukos, Dimitrios\|Kotoula, Vassiliki\|Kalofono
PMID:	25956750

1192.
Journal:	Semin Oncol. 2015 Jun;42(3):474-83.
Title:	PD-L1 blockade for cancer treatment: MEDI4736.
Author:	Ibrahim, Ramy\|Stewart, Ross\|Shalabi, Aiman
PMID:	25965366

1193.
Journal:	PLoS One. 2015 May 13;10(5):e0124612.
Title:	Immune response gene expression in colorectal cancer carries distinct prognostic implications according to tissue, stage and site: a prospective retrospective translational study in the context of a hellenic cooperative oncology group randomised trial.
Author:	Pentheroudakis, George\|Raptou, Georgia\|Kotoula, Vassiliki\|Wirtz, Ralph M\|Vrettou, Eleni\|Karavasilis, Vasilios\|Gourgioti, Georgia\|Gakou, Chryssa\|Syrigos, Konstantinos N\|Bournakis, Evangelos\|Rallis, Grigorios\|Varthalitis, Ioannis\|Galani, Eleni\|Lazaridis, Ge
PMID:	25970543

1194.
Journal:	Am J Clin Pathol. 2015 Jun;143(6):879-88.
Title:	Endoscopic ultrasound fine-needle aspiration cytology mutation profiling using targeted next-generation sequencing: personalized care for rectal cancer.
Author:	Gleeson, Ferga C\|Kipp, Benjamin R\|Voss, Jesse S\|Campion, Michael B\|Minot, Douglas M\|Tu, Zheng J\|Klee, Eric W\|Sciallis, Andrew P\|Graham, Rondell P\|Lazaridis, Konstantinos N\|Henry, Michael R\|Levy, Michael J
PMID:	25972331

1195.
Journal:	Am J Cancer Res. 2015 Jan 15;5(2):674-88. eCollection 2015.
Title:	A specific KRAS codon 13 mutation is an independent predictor for colorectal cancer metachronous distant metastases.
Author:	Feng, Qingyang\|Liang, Li\|Ren, Li\|Chen, Jingwen\|Wei, Ye\|Chang, Wenju\|Zhu, Dexiang\|Lin, Qi\|Zheng, Peng\|Xu, Jianmin
PMID:	25973306

1196.
Journal:	Br J Cancer. 2015 Jun 9;112(12):1966-75.
Title:	Combination of microsatellite instability and BRAF mutation status for subtyping colorectal cancer.
Author:	Seppala, T T\|Bohm, J P\|Friman, M\|Lahtinen, L\|Vayrynen, V M J\|Liipo, T K E\|Ristimaki, A P\|Kairaluoma, M V J\|Kellokumpu, I H\|Kuopio, T H I\|Mecklin, J-P
PMID:	25973534

1197.
Journal:	Anticancer Drugs. 2015 Aug;26(7):754-62.
Title:	AM251 induces apoptosis and G2/M cell cycle arrest in A375 human melanoma cells.
Author:	Carpi, Sara\|Fogli, Stefano\|Romanini, Antonella\|Pellegrino, Mario\|Adinolfi, Barbara\|Podesta, Adriano\|Costa, Barbara\|Da Pozzo, Eleonora\|Martini, Claudia\|Breschi, Maria Cristina\|Nieri, Paola
PMID:	25974027

1198.
Journal:	Zhonghua Bing Li Xue Za Zhi. 2015 Apr;44(4):254-7.
Title:	[Detection of KRAS,NRAS and BRAF gene mutations in colorectal carcinoma].
Author:	Zhang, Keping\|Xu, Jie\|Yan, Lixu\|Liu, Xunhua\|Xu, Fangping\|Liu, Yanhui
PMID:	25975908

1199.
Journal:	Expert Rev Mol Diagn. 2015;15(8):979-87.
Title:	The distinctive molecular, pathological and clinical characteristics of BRAF-mutant colorectal tumors.
Author:	Scartozzi, Mario\|Giampieri, Riccardo\|Aprile, Giuseppe\|Iacono, Donatella\|Santini, Daniele\|dell'Aquila, Emanuela\|Silvestris, Nicola\|Gnoni, Antonio\|Bonotto, Marta\|Puzzoni, Marco\|Demurtas, Laura\|Cascinu, Stefano
PMID:	25975986

1200.
Journal:	Cancer Epidemiol Biomarkers Prev. 2015 Jul;24(7):1130-7.
Title:	Prediagnostic Physical Activity and Colorectal Cancer Survival: Overall and Stratified by Tumor Characteristics.
Author:	Hardikar, Sheetal\|Newcomb, Polly A\|Campbell, Peter T\|Win, Aung Ko\|Lindor, Noralane M\|Buchanan, Daniel D\|Makar, Karen W\|Jenkins, Mark A\|Potter, John D\|Phipps, Amanda I
PMID:	25976417

1201.
Journal:	Cancer Cell Int. 2015 Apr 15;15:40.
Title:	MicroRNA-378-5p suppresses cell proliferation and induces apoptosis in colorectal cancer cells by targeting BRAF.
Author:	Wang, Zhenlei\|Ma, Bin\|Ji, Xiaopin\|Deng, Yang\|Zhang, Tao\|Zhang, Xiaojian\|Gao, Haoji\|Sun, Hanxing\|Wu, Haoxuan\|Chen, Xianze\|Zhao, Ren
PMID:	25977643

1202.
Journal:	Eur J Cancer. 2015 Jul;51(11):1405-14.
Title:	Location of colon cancer (right-sided versus left-sided) as a prognostic factor and a predictor of benefit from cetuximab in NCIC CO.17.
Author:	Brule, S Y\|Jonker, D J\|Karapetis, C S\|O'Callaghan, C J\|Moore, M J\|Wong, R\|Tebbutt, N C\|Underhill, Cr\|Yip, D\|Zalcberg, J R\|Tu, D\|Goodwin, R A
PMID:	25979833

1203.
Journal:	Gastroenterol Res Pract. 2015;2015:753903.
Title:	KRAS and BRAF Mutation Detection: Is Immunohistochemistry a Possible Alternative to Molecular Biology in Colorectal Cancer?
Author:	Piton, Nicolas\|Borrini, Francesco\|Bolognese, Antonio\|Lamy, Aude\|Sabourin, Jean-Christophe
PMID:	25983749

1204.
Journal:	Am Soc Clin Oncol Educ Book. 2015:e149-56.
Title:	Overcoming Resistance to Anti-EGFR Therapy in Colorectal Cancer.
Author:	Dienstmann, Rodrigo\|Salazar, Ramon\|Tabernero, Josep
PMID:	25993166

1205.
Journal:	Cancer Epidemiol Biomarkers Prev. 2015 Jul;24(7):1046-51.
Title:	PIK3CA Somatic Mutation Status in Relation to Patient and Tumor Factors in Racial/Ethnic Minorities with Colorectal Cancer.
Author:	Phipps, Amanda I\|Ahnen, Dennis J\|Cheng, Iona\|Newcomb, Polly A\|Win, Aung Ko\|Burnett, Terrilea
PMID:	25994739

1206.
Journal:	Hum Pathol. 2015 Jul;46(7):933-8.
Title:	Traditional serrated adenoma: an update.
Author:	Bettington, Mark L\|Chetty, Runjan
PMID:	26001333

1207.
Journal:	ACS Med Chem Lett. 2015 Mar 18;6(5):543-7.
Title:	N-(3-Ethynyl-2,4-difluorophenyl)sulfonamide Derivatives as Selective Raf Inhibitors.
Author:	Li, Yingjun\|Cheng, Huimin\|Zhang, Zhang\|Zhuang, Xiaoxi\|Luo, Jinfeng\|Long, Huoyou\|Zhou, Yang\|Xu, Yong\|Taghipouran, Rana\|Li, Dan\|Patterson, Adam\|Smaill, Jeff\|Tu, Zhengchao\|Wu, Donghai\|Ren, Xiaomei\|Ding, Ke
PMID:	26005530

1208.
Journal:	Rev Med Chil. 2015 Mar;143(3):310-9.
Title:	[Molecular analysis of sporadic colon cancer].
Author:	Hurtado, Claudia\|Wielandt, Ana Maria\|Zarate, Alejandro J\|Kronberg, Udo\|Castro, Magdalena\|Yamagiwa, Ken\|Ito, Takashi\|Eishi, Yoshinobu\|Contreras, Luis\|Lopez-Kostner, Francisco
PMID:	26005817

1209.
Journal:	Clin Nucl Med. 2015 Aug;40(8):621-6.
Title:	Genetic Alterations in Colorectal Cancer Have Different Patterns on 18F-FDG PET/CT.
Author:	Chen, Shang-Wen\|Lin, Chien-Yu\|Ho, Cheng-Man\|Chang, Ya-Sian\|Yang, Shu-Fen\|Kao, Chia-Hung\|Chang, Jan-Gowth
PMID:	26018692

1210.
Journal:	Int J Med Sci. 2015 Apr 27;12(4):349-53.
Title:	PIK3CA Amplification Is Common in Left Side-Tubular Adenomas but Uncommon Sessile Serrated Adenomas Exclusively with KRAS Mutation.
Author:	Lee, Hyunsu\|Lee, Jae-Ho\|Kim, Dae-Kwang\|Choi, In-Jang\|Hwang, Ilseon\|Kang, Yu-Na\|Kim, Shin
PMID:	26019684

1211.
Journal:	Drug Resist Updat. 2015 May;20:39-70.
Title:	Pharmacogenomics of intrinsic and acquired pharmacoresistance in colorectal cancer: Toward targeted personalized therapy.
Author:	De Mattia, Elena\|Cecchin, Erika\|Toffoli, Giuseppe
PMID:	26027741

1212.
Journal:	Arch Pathol Lab Med. 2015 Jun;139(6):730-41.
Title:	Molecular and histologic considerations in the assessment of serrated polyps.
Author:	Yang, Hui-Min\|Mitchell, James M\|Sepulveda, Jorge L\|Sepulveda, Antonia R
PMID:	26030242

1213.
Journal:	Oncotarget. 2015 May 30;6(15):13334-46.
Title:	Effects of RAL signal transduction in KRAS- and BRAF-mutated cells and prognostic potential of the RAL signature in colorectal cancer.
Author:	Gyorffy, Balazs\|Stelniec-Klotz, Iwona\|Sigler, Christian\|Kasack, Katharina\|Redmer, Torben\|Qian, Yu\|Schafer, Reinhold
PMID:	26033452

1214.
Journal:	Cancer Epidemiol Biomarkers Prev. 2015 Aug;24(8):1229-38.
Title:	Association between body mass index and mortality for colorectal cancer survivors: overall and by tumor molecular phenotype.
Author:	Campbell, Peter T\|Newton, Christina C\|Newcomb, Polly A\|Phipps, Amanda I\|Ahnen, Dennis J\|Baron, John A\|Buchanan, Daniel D\|Casey, Graham\|Cleary, Sean P\|Cotterchio, Michelle\|Farris, Alton B\|Figueiredo, Jane C\|Gallinger, Steven\|Green, Roger C\|Haile, Robert W\|
PMID:	26038390

1215.
Journal:	Expert Opin Investig Drugs. 2015;24(9):1185-98.
Title:	Role and mechanisms of resistance of epidermal growth factor receptor antagonists in the treatment of colorectal cancer.
Author:	Rihawi, Karim\|Giampieri, Riccardo\|Scartozzi, Mario\|Pusceddu, Valeria\|Bonotto, Marta\|Fasola, Gianpiero\|Cascinu, Stefano\|Aprile, Giuseppe
PMID:	26044119

1216.
Journal:	Mar Drugs. 2015 Jun 5;13(6):3625-39.
Title:	Activation of RAF1 (c-RAF) by the Marine Alkaloid Lasonolide A Induces Rapid Premature Chromosome Condensation.
Author:	Josse, Rozenn\|Zhang, Yong-Wei\|Giroux, Valentin\|Ghosh, Arun K\|Luo, Ji\|Pommier, Yves
PMID:	26058013

1217.
Journal:	Cancer Prev Res (Phila). 2015 Aug;8(8):702-11.
Title:	Aberrant TET1 Methylation Closely Associated with CpG Island Methylator Phenotype in Colorectal Cancer.
Author:	Ichimura, Norihisa\|Shinjo, Keiko\|An, Byonggu\|Shimizu, Yasuhiro\|Yamao, Kenji\|Ohka, Fumiharu\|Katsushima, Keisuke\|Hatanaka, Akira\|Tojo, Masayuki\|Yamamoto, Eiichiro\|Suzuki, Hiromu\|Ueda, Minoru\|Kondo, Yutaka
PMID:	26063725

1218.
Journal:	Int J Clin Exp Med. 2015 Mar 15;8(3):3241-57. eCollection 2015.
Title:	Correlation between smoking history and molecular pathways in sporadic colorectal cancer: a meta-analysis.
Author:	Chen, Ke\|Xia, Guanggai\|Zhang, Changhua\|Sun, Yunwei
PMID:	26064214

1219.
Journal:	World J Gastroenterol. 2015 Jun 7;21(21):6470-8.
Title:	Different treatment strategies and molecular features between right-sided and left-sided colon cancers.
Author:	Shen, Hong\|Yang, Jiao\|Huang, Qing\|Jiang, Meng-Jie\|Tan, Yi-Nuo\|Fu, Jian-Fei\|Zhu, Li-Zhen\|Fang, Xue-Feng\|Yuan, Ying
PMID:	26074686

1220.
Journal:	Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2015 Sep;159(3):466-71.
Title:	Comparison of the prevalence of KRAS-LCS6 polymorphism (rs61764370) within different tumour types (colorectal, breast, non-small cell lung cancer and brain tumours). A study of the Czech population.
Author:	Uvirova, Magdalena\|Simova, Jarmila\|Kubova, Barbora\|Dvorackova, Nina\|Tomaskova, Hana\|Sedivcova, Monika\|Dite, Petr
PMID:	26077004

1221.
Journal:	Oncotarget. 2015 Oct 6;6(30):28929-37.
Title:	Identification and characterization of RET fusions in advanced colorectal cancer.
Author:	Le Rolle, Anne-France\|Klempner, Samuel J\|Garrett, Christopher R\|Seery, Tara\|Sanford, Eric M\|Balasubramanian, Sohail\|Ross, Jeffrey S\|Stephens, Philip J\|Miller, Vincent A\|Ali, Siraj M\|Chiu, Vi K
PMID:	26078337

1222.
Journal:	Oncotarget. 2015 Sep 8;6(26):22298-309.
Title:	Targeting TRAP1 as a downstream effector of BRAF cytoprotective pathway: a novel strategy for human BRAF-driven colorectal carcinoma.
Author:	Condelli, Valentina\|Maddalena, Francesca\|Sisinni, Lorenza\|Lettini, Giacomo\|Matassa, Danilo Swann\|Piscazzi, Annamaria\|Palladino, Giuseppe\|Amoroso, Maria Rosaria\|Esposito, Franca\|Landriscina, Matteo
PMID:	26084290

1223.
Journal:	Autophagy. 2015;11(8):1373-88.
Title:	The epithelial polarity regulator LGALS9/galectin-9 induces fatal frustrated autophagy in KRAS mutant colon carcinoma that depends on elevated basal autophagic flux.
Author:	Wiersma, Valerie R\|de Bruyn, Marco\|Wei, Yunwei\|van Ginkel, Robert J\|Hirashima, Mitsuomi\|Niki, Toshiro\|Nishi, Nozomu\|Zhou, Jin\|Pouwels, Simon D\|Samplonius, Douwe F\|Nijman, Hans W\|Eggleton, Paul\|Helfrich, Wijnand\|Bremer, Edwin
PMID:	26086204

1224.
Journal:	Pathol Res Pract. 2015 Aug;211(8):601-9.
Title:	Expression of cancer stem cell markers in metastatic colorectal cancer correlates with liver metastasis, but not with metastasis to the central nervous system.
Author:	Michl, Marlies\|Heinemann, Volker\|Jung, Andreas\|Engel, Jutta\|Kirchner, Thomas\|Neumann, Jens
PMID:	26092596

1225.
Journal:	Int J Mol Med. 2015 Aug;36(2):511-7.
Title:	Multivariate analysis as a method for evaluating the pathogenicity of novel genetic MLH1 variants in patients with colorectal cancer and microsatellite instability.
Author:	Duraturo, Francesca\|Liccardo, Raffaella\|Cavallo, Angela\|De Rosa, Marina\|Rossi, Giovanni Battista\|Izzo, Paola
PMID:	26096739

1226.
Journal:	Radiother Oncol. 2015 Sep;116(3):510-6.
Title:	EGFR and beta1-integrin targeting differentially affect colorectal carcinoma cell radiosensitivity and invasion.
Author:	Poschau, Mandy\|Dickreuter, Ellen\|Singh-Muller, Jenny\|Zscheppang, Katja\|Eke, Iris\|Liersch, Torsten\|Cordes, Nils
PMID:	26096850

1227.
Journal:	Oncoscience. 2015 Mar 23;2(5):508-16.
Title:	Methylation changes in the TFAP2E promoter region are associated with BRAF mutation and poorer overall & disease free survival in colorectal cancer.
Author:	Beggs, Andrew D\|Dilworth, Mark P\|Domingo, Enric\|Midgley, Rachel\|Kerr, David\|Tomlinson, Ian P M\|Middleton, Gary W
PMID:	26097884

1228.
Journal:	Diagn Pathol. 2015 Jun 24;10:77.
Title:	Epigenetics could explain some Moroccan population colorectal cancers peculiarities: microsatellite instability pathway exploration.
Author:	Sekal, Mohammed\|Ameurtesse, Hassania\|Chbani, Laila\|Ouldim, Karim\|Bennis, Sanae\|Abkari, Mohammed\|Boulouz, Amal\|Benajah, Dafr Allah\|Benjelloun, Basher\|Ousadden, Abdelmalek\|Ait Taleb, Khalid\|Ait Laalim, Said\|Toghrai, Imane\|Mazaz, Khalid\|Arifi, Samia\|Mellas,
PMID:	26104511

1229.
Journal:	Biomed Res Int. 2015;2015:185404.
Title:	Lack of Association between Membrane-Type 1 Matrix Metalloproteinase Expression and Clinically Relevant Molecular or Morphologic Tumor Characteristics at the Leading Edge of Invasive Colorectal Carcinoma.
Author:	Arndt, Annette\|Kraft, Klaus\|Wardelmann, Eva\|Steinestel, Konrad
PMID:	26106602

1230.
Journal:	World J Gastroenterol. 2015 Jun 21;21(23):7281-8.
Title:	Bevacizumab plus XELOX as first-line treatment of metastatic colorectal cancer: The OBELIX study.
Author:	Antonuzzo, Lorenzo\|Giommoni, Elisa\|Pastorelli, Davide\|Latiano, Tiziana\|Pavese, Ida\|Azzarello, Domenico\|Aieta, Michele\|Pastina, Ilaria\|Di Fabio, Francesca\|Bertolini, Alessandro\|Corsi, Domenico Cristiano\|Mogavero, Selene\|Angelini, Valentina\|Pazzagli, Mario\|
PMID:	26109816

1231.
Journal:	Am J Epidemiol. 2015 Aug 1;182(3):263-70.
Title:	A Meta-Regression Method for Studying Etiological Heterogeneity Across Disease Subtypes Classified by Multiple Biomarkers.
Author:	Wang, Molin\|Kuchiba, Aya\|Ogino, Shuji
PMID:	26116215

1232.
Journal:	Bull Cancer. 2015 Jun;102(6 Suppl 1):S72-81.
Title:	[DNA mismatch repair and BRAF status in colorectal cancer: Interest for the therapeutic management?].
Author:	Cohen, Romain\|Cervera, Pascale\|Svrcek, Magali\|Dumont, Clement\|Garcia, Marie-Line\|Chibaudel, Benoist\|de Gramont, Aimery\|Pocard, Marc\|Duval, Alex\|Flejou, Jean-Francois\|Andre, Thierry
PMID:	26118880

1233.
Journal:	J Hum Genet. 2015 Oct;60(10):589-96.
Title:	Genetic mutations in human rectal cancers detected by targeted sequencing.
Author:	Bai, Jun\|Gao, Jinglong\|Mao, Zhijun\|Wang, Jianhua\|Li, Jianhui\|Li, Wensheng\|Lei, Yu\|Li, Shuaishuai\|Wu, Zhuo\|Tang, Chuanning\|Jones, Lindsey\|Ye, Hua\|Lou, Feng\|Liu, Zhiyuan\|Dong, Zhishou\|Guo, Baishuai\|Huang, Xue F\|Chen, Si-Yi\|Zhang, Enke
PMID:	26134512

1234.
Journal:	Exp Ther Med. 2015 May;9(5):1719-1722.
Title:	Intra-tumor heterogeneity of BRAF V600E mutation in lung adenocarcinomas.
Author:	Tatematsu, Tsutomu\|Sasaki, Hidefumi\|Shimizu, Shigeki\|Hikosaka, Y U\|Okuda, Katsuhiro\|Haneda, Hiroshi\|Moriyama, Satoru\|Yano, Motoki\|Fujii, Yoshitaka
PMID:	26136882

1235.
Journal:	Cancer Treat Rev. 2015 Sep;41(8):671-9.
Title:	Rectal and colon cancer: Not just a different anatomic site.
Author:	Tamas, K\|Walenkamp, A M E\|de Vries, E G E\|van Vugt, M A T M\|Beets-Tan, R G\|van Etten, B\|de Groot, D J A\|Hospers, G A P
PMID:	26145760

1236.
Journal:	J Natl Cancer Inst. 2015 Jul 9;107(10). pii: djv186.
Title:	Racial Differences in BRAF/KRAS Mutation Rates and Survival in Stage III Colon Cancer Patients.
Author:	Yoon, Harry H\|Shi, Qian\|Alberts, Steven R\|Goldberg, Richard M\|Thibodeau, Stephen N\|Sargent, Daniel J\|Sinicrope, Frank A
PMID:	26160882

1237.
Journal:	Anal Bioanal Chem. 2015 Nov;407(27):8321-31.
Title:	In vitro prediction of the efficacy of molecularly targeted cancer therapy by Raman spectral imaging.
Author:	Yosef, Hesham K\|Mavarani, Laven\|Maghnouj, Abdelouahid\|Hahn, Stephan\|El-Mashtoly, Samir F\|Gerwert, Klaus
PMID:	26168967

1238.
Journal:	Oncotarget. 2015 Sep 22;6(28):26278-90.
Title:	MGL ligand expression is correlated to BRAF mutation and associated with poor survival of stage III colon cancer patients.
Author:	Lenos, Kristiaan\|Goos, Jeroen A C M\|Vuist, Ilona M\|den Uil, Sjoerd H\|Delis-van Diemen, Pien M\|Belt, Eric J Th\|Stockmann, Hein B A C\|Bril, Herman\|de Wit, Meike\|Carvalho, Beatriz\|Giblett, Susan\|Pritchard, Catrin A\|Meijer, Gerrit A\|van Kooyk, Yvette\|Fijneman
PMID:	26172302

1239.
Journal:	JAMA Oncol. 2015 Aug;1(5):653-61.
Title:	Fusobacterium nucleatum and T Cells in Colorectal Carcinoma.
Author:	Mima, Kosuke\|Sukawa, Yasutaka\|Nishihara, Reiko\|Qian, Zhi Rong\|Yamauchi, Mai\|Inamura, Kentaro\|Kim, Sun A\|Masuda, Atsuhiro\|Nowak, Jonathan A\|Nosho, Katsuhiko\|Kostic, Aleksandar D\|Giannakis, Marios\|Watanabe, Hideo\|Bullman, Susan\|Milner, Danny A\|Harris, Curti
PMID:	26181352

1240.
Journal:	JAMA Oncol. 2015 Aug;1(5):686-7.
Title:	Axillary Lymph Node Involvement, a Unique Pattern of Metastasis in BRAF-Mutant Colorectal Cancer.
Author:	Lipsyc, Marla D\|Yaeger, Rona\|Dengel, Lynn T\|Saltz, Leonard
PMID:	26182332

1241.
Journal:	Dan Med J. 2015 Jul;62(7).
Title:	Computed tomography assessment of early response to neoadjuvant therapy in colon cancer.
Author:	Dam, Claus\|Lund-Rasmussen, Vera\|Ploen, John\|Jakobsen, Anders\|Rafaelsen, Soren Rafael
PMID:	26183044

1242.
Journal:	Clin Cancer Res. 2015 Dec 1;21(23):5294-304.
Title:	Analysis of Molecular Markers by Anatomic Tumor Site in Stage III Colon Carcinomas from Adjuvant Chemotherapy Trial NCCTG N0147 (Alliance).
Author:	Sinicrope, Frank A\|Mahoney, Michelle R\|Yoon, Harry H\|Smyrk, Thomas C\|Thibodeau, Stephen N\|Goldberg, Richard M\|Nelson, Garth D\|Sargent, Daniel J\|Alberts, Steven R
PMID:	26187617

1243.
Journal:	J Clin Pathol. 2015 Dec;68(12):1036-9.
Title:	Screening for Lynch syndrome and referral to clinical genetics by selective mismatch repair protein immunohistochemistry testing: an audit and cost analysis.
Author:	Colling, Richard\|Church, David N\|Carmichael, Juliet\|Murphy, Lucinda\|East, James\|Risby, Peter\|Kerr, Rachel\|Chetty, Runjan\|Wang, Lai Mun
PMID:	26201544

1244.
Journal:	Mol Cancer Ther. 2015 Oct;14(10):2374-81.
Title:	Polymorphisms in Genes Involved in EGFR Turnover Are Predictive for Cetuximab Efficacy in Colorectal Cancer.
Author:	Stintzing, Sebastian\|Zhang, Wu\|Heinemann, Volker\|Neureiter, Daniel\|Kemmerling, Ralf\|Kirchner, Thomas\|Jung, Andreas\|Folwaczny, Matthias\|Yang, Dongyun\|Ning, Yan\|Sebio, Ana\|Stremitzer, Stefan\|Sunakawa, Yu\|Matsusaka, Satoshi\|Yamauchi, Shinichi\|Loupakis, Fotio
PMID:	26206335

1245.
Journal:	Mol Cancer Ther. 2015 Oct;14(10):2187-97.
Title:	BGB-283, a Novel RAF Kinase and EGFR Inhibitor, Displays Potent Antitumor Activity in BRAF-Mutated Colorectal Cancers.
Author:	Tang, Zhiyu\|Yuan, Xi\|Du, Rong\|Cheung, Shing-Hu\|Zhang, Guoliang\|Wei, Jing\|Zhao, Yuan\|Feng, Yingcai\|Peng, Hao\|Zhang, Yi\|Du, Yunguang\|Hu, Xiaoxia\|Gong, Wenfeng\|Liu, Yong\|Gao, Yajuan\|Liu, Ye\|Hao, Rui\|Li, Shengjian\|Wang, Shaohui\|Ji, Jiafu\|Zhang, Lianhai\|Li, Sh
PMID:	26208524

1246.
Journal:	Gastroenterology. 2015 Oct;149(5):1177-1190.e3.
Title:	Genetics and Genetic Biomarkers in Sporadic Colorectal Cancer.
Author:	Carethers, John M\|Jung, Barbara H
PMID:	26216840

1247.
Journal:	Cancer. 2015 Nov 1;121(21):3799-808.
Title:	Molecular markers and pathway analysis of colorectal carcinoma in the Middle East.
Author:	Beg, Shaham\|Siraj, Abdul K\|Prabhakaran, Sarita\|Bu, Rong\|Al-Rasheed, Maha\|Sultana, Mehar\|Qadri, Zeeshan\|Al-Assiri, Mohammed\|Sairafi, Rami\|Al-Dayel, Fouad\|Al-Sanea, Nasser\|Uddin, Shahab\|Al-Kuraya, Khawla S
PMID:	26218848

1248.
Journal:	Diagn Pathol. 2015 Jul 30;10:132.
Title:	Detection of KRAS, NRAS and BRAF by mass spectrometry - a sensitive, reliable, fast and cost-effective technique.
Author:	Kriegsmann, Mark\|Arens, Norbert\|Endris, Volker\|Weichert, Wilko\|Kriegsmann, Jorg
PMID:	26220423

1249.
Journal:	Mod Pathol. 2015 Oct;28(10):1390-9.
Title:	Performance characteristics of next-generation sequencing in clinical mutation detection of colorectal cancers.
Author:	Haley, Lisa\|Tseng, Li-Hui\|Zheng, Gang\|Dudley, Jonathan\|Anderson, Derek A\|Azad, Nilofer S\|Gocke, Christopher D\|Eshleman, James R\|Lin, Ming-Tseh
PMID:	26226847

1250.
Journal:	Cancer Genet. 2015 Sep;208(9):441-7.
Title:	Diagnostic yield of targeted next generation sequencing in various cancer types: an information-theoretic approach.
Author:	Hagemann, Ian S\|O'Neill, Patrick K\|Erill, Ivan\|Pfeifer, John D
PMID:	26227479

1251.
Journal:	BMC Cancer. 2015 Aug 1;15:567.
Title:	Durable recurrence-free survival after pneumonectomy for late lung metastasis from rectal cancer: case report with genetic and epigenetic analyses.
Author:	Imperatori, Andrea\|Rotolo, Nicola\|Dominioni, Lorenzo\|Nardecchia, Elisa\|Cattoni, Maria\|Cimetti, Laura\|Riva, Cristina\|Sessa, Fausto\|Furlan, Daniela
PMID:	26231173

1252.
Journal:	Pharmacogenomics. 2015;16(10):1189-222.
Title:	Molecular biomarkers in colorectal carcinoma.
Author:	Puerta-Garcia, Elena\|Canadas-Garre, Marisa\|Calleja-Hernandez, Miguel Angel
PMID:	26237292

1253.
Journal:	Cancer Discov. 2015 Aug;5(8):832-41.
Title:	HER2 activating mutations are targets for colorectal cancer treatment.
Author:	Kavuri, Shyam M\|Jain, Naveen\|Galimi, Francesco\|Cottino, Francesca\|Leto, Simonetta M\|Migliardi, Giorgia\|Searleman, Adam C\|Shen, Wei\|Monsey, John\|Trusolino, Livio\|Jacobs, Samuel A\|Bertotti, Andrea\|Bose, Ron
PMID:	26243863

1254.
Journal:	Pol J Pathol. 2015 Jun;66(2):109-20.
Title:	Can the histological type of colorectal cancer determine the carcinogenesis pathway?
Author:	Kolos, Malgorzata\|Wasaznik-Jedras, Anna\|Nasierowska-Guttmejer, Anna
PMID:	26247523

1255.
Journal:	Oncogenesis. 2015 Aug 10;4:e162.
Title:	SPINK1 promotes colorectal cancer progression by downregulating Metallothioneins expression.
Author:	Tiwari, R\|Pandey, S K\|Goel, S\|Bhatia, V\|Shukla, S\|Jing, X\|Dhanasekaran, S M\|Ateeq, B
PMID:	26258891

1256.
Journal:	Clin Cancer Res. 2015 Dec 15;21(24):5499-5510.
Title:	MEK plus PI3K/mTORC1/2 Therapeutic Efficacy Is Impacted by TP53 Mutation in Preclinical Models of Colorectal Cancer.
Author:	Garcia-Garcia, Celina\|Rivas, Martin A\|Ibrahim, Yasir H\|Calvo, Maria Teresa\|Gris-Oliver, Albert\|Rodriguez, Olga\|Grueso, Judit\|Anton, Pilar\|Guzman, Marta\|Aura, Claudia\|Nuciforo, Paolo\|Jessen, Katti\|Argiles, Guillem\|Dienstmann, Rodrigo\|Bertotti, Andrea\|Truso
PMID:	26272063

1257.
Journal:	N Engl J Med. 2015 Aug 20;373(8):726-36.
Title:	Vemurafenib in Multiple Nonmelanoma Cancers with BRAF V600 Mutations.
Author:	Hyman, David M\|Puzanov, Igor\|Subbiah, Vivek\|Faris, Jason E\|Chau, Ian\|Blay, Jean-Yves\|Wolf, Jurgen\|Raje, Noopur S\|Diamond, Eli L\|Hollebecque, Antoine\|Gervais, Radj\|Elez-Fernandez, Maria Elena\|Italiano, Antoine\|Hofheinz, Ralf-Dieter\|Hidalgo, Manuel\|Chan, Em
PMID:	26287849

1258.
Journal:	PLoS One. 2015 Aug 20;10(8):e0133836.
Title:	Comprehensive DNA Methylation Analysis Reveals a Common Ten-Gene Methylation Signature in Colorectal Adenomas and Carcinomas.
Author:	Patai, Arpad V\|Valcz, Gabor\|Hollosi, Peter\|Kalmar, Alexandra\|Peterfia, Balint\|Patai, Arpad\|Wichmann, Barnabas\|Spisak, Sandor\|Bartak, Barbara Kinga\|Leiszter, Katalin\|Toth, Kinga\|Sipos, Ferenc\|Kovalszky, Ilona\|Peter, Zoltan\|Miheller, Pal\|Tulassay, Zsolt\|Mol
PMID:	26291085

1259.
Journal:	Biochem Biophys Res Commun. 2015 Sep 25;465(3):594-600.
Title:	Fentanyl inhibits the invasion and migration of colorectal cancer cells via inhibiting the negative regulation of Ets-1 on BANCR.
Author:	Li, Ai-xiang\|Xin, Wen-qi\|Ma, Chuan-gen
PMID:	26296467

1260.
Journal:	Oncotarget. 2015 Aug 28;6(25):20785-800.
Title:	Similar but different: distinct roles for KRAS and BRAF oncogenes in colorectal cancer development and therapy resistance.
Author:	Morkel, Markus\|Riemer, Pamela\|Blaker, Hendrik\|Sers, Christine
PMID:	26299805

1261.
Journal:	Mol Biol (Mosk). 2015 Jul-Aug;49(4):617-27.
Title:	[Biochip detection of KRAS, BRAF, and PIK3CA somatic mutations in colorectal cancer patients].
Author:	Emelyanova, M A\|Amossenko, F A\|Semyanikhina, A V\|Aliev, V A\|Barsukov, Yu A\|Lyubchenko, L N\|Nasedkina, T V
PMID:	26299862

1262.
Journal:	Br J Cancer. 2015 Sep 15;113(6):979-88.
Title:	Wild-type APC predicts poor prognosis in microsatellite-stable proximal colon cancer.
Author:	Jorissen, Robert N\|Christie, Michael\|Mouradov, Dmitri\|Sakthianandeswaren, Anuratha\|Li, Shan\|Love, Christopher\|Xu, Zheng-Zhou\|Molloy, Peter L\|Jones, Ian T\|McLaughlin, Stephen\|Ward, Robyn L\|Hawkins, Nicholas J\|Ruszkiewicz, Andrew R\|Moore, James\|Burgess, Ant
PMID:	26305864

1263.
Journal:	Bioorg Med Chem Lett. 2015 Oct 1;25(19):4287-92.
Title:	Probing a 3,4'-bis-guanidinium diaryl derivative as an allosteric inhibitor of the Ras pathway.
Author:	Diez-Cecilia, Elena\|Carson, Robert\|Kelly, Brendan\|van Schaeybroeck, Sandra\|Murray, James T\|Rozas, Isabel
PMID:	26318998

1264.
Journal:	J Mol Diagn. 2015 Nov;17(6):705-14.
Title:	MSIplus for Integrated Colorectal Cancer Molecular Testing by Next-Generation Sequencing.
Author:	Hempelmann, Jennifer A\|Scroggins, Sheena M\|Pritchard, Colin C\|Salipante, Stephen J
PMID:	26322950

1265.
Journal:	Br J Cancer. 2015 Sep 15;113(6):914-20.
Title:	KRAS, NRAS, BRAF mutation comparison of endoscopic and surgically removed primary CRC paired samples: is endoscopy biopsy material adequate for molecular evaluation?
Author:	Saridaki, Z\|Saegart, X\|De Vriendt, V\|Hatzidaki, D\|Palmans, S\|De Smedt, L\|De Hertogh, G\|Tejpar, S
PMID:	26325103

1266.
Journal:	Ther Adv Med Oncol. 2015 Sep;7(5):252-62.
Title:	Precision medicine in colorectal cancer: the molecular profile alters treatment strategies.
Author:	Tran, Nguyen H\|Cavalcante, Ludmila L\|Lubner, Sam J\|Mulkerin, Daniel L\|LoConte, Noelle K\|Clipson, Linda\|Matkowskyj, Kristina A\|Deming, Dustin A
PMID:	26327923

1267.
Journal:	J Transl Med. 2015 Sep 3;13:287.
Title:	The Italian external quality assessment for RAS testing in colorectal carcinoma identifies methods-related inter-laboratory differences.
Author:	Normanno, Nicola\|Pinto, Carmine\|Castiglione, Francesca\|Fenizia, Francesca\|Barberis, Massimo\|Marchetti, Antonio\|Fontanini, Gabriella\|De Rosa, Gaetano\|Taddei, Gian Luigi
PMID:	26335936

1268.
Journal:	Gastroenterol Rep (Oxf). 2015 Nov;3(4):269-76.
Title:	Molecular phenotypes of colorectal cancer and potential clinical applications.
Author:	Kocarnik, Jonathan M\|Shiovitz, Stacey\|Phipps, Amanda I
PMID:	26337942

1269.
Journal:	Future Oncol. 2015 Oct;11(19):2711-2719.
Title:	Precision medicine in colorectal cancer: evolving genomic landscape and emerging consensus.
Author:	Fisher, Kurt W\|Lopez-Beltran, Antonio\|Montironi, Rodolfo\|Cheng, Liang
PMID:	26338658

1270.
Journal:	Cancer Lett. 2015 Dec 28;369(2):368-75.
Title:	Expression of tumor-related Rac1b antagonizes B-Raf-induced senescence in colorectal cells.
Author:	Henriques, Andreia F A\|Barros, Patricia\|Moyer, Mary Pat\|Matos, Paulo\|Jordan, Peter
PMID:	26341689

1271.
Journal:	Cell. 2015 Sep 10;162(6):1257-70.
Title:	Cyclooxygenase-Dependent Tumor Growth through Evasion of Immunity.
Author:	Zelenay, Santiago\|van der Veen, Annemarthe G\|Bottcher, Jan P\|Snelgrove, Kathryn J\|Rogers, Neil\|Acton, Sophie E\|Chakravarty, Probir\|Girotti, Maria Romina\|Marais, Richard\|Quezada, Sergio A\|Sahai, Erik\|Reis e Sousa, Caetano
PMID:	26343581

1272.
Journal:	Hum Pathol. 2015 Nov;46(11):1573-81.
Title:	Expression of the hyaluronan-mediated motility receptor RHAMM in tumor budding cells identifies aggressive colorectal cancers.
Author:	Koelzer, Viktor Hendrik\|Huber, Bettina\|Mele, Valentina\|Iezzi, Giandomenica\|Trippel, Mafalda\|Karamitopoulou, Eva\|Zlobec, Inti\|Lugli, Alessandro
PMID:	26351067

1273.
Journal:	Mol Cancer Ther. 2015 Dec;14(12):2700-11.
Title:	Combined Pan-RAF and MEK Inhibition Overcomes Multiple Resistance Mechanisms to Selective RAF Inhibitors.
Author:	Whittaker, Steven R\|Cowley, Glenn S\|Wagner, Steve\|Luo, Flora\|Root, David E\|Garraway, Levi A
PMID:	26351322

1274.
Journal:	Pathology. 2015 Oct;47(6):551-6.
Title:	KRAS, NRAS, BRAF mutations and high counts of poorly differentiated clusters of neoplastic cells in colorectal cancer: observational analysis of 175 cases.
Author:	Barresi, Valeria\|Bonetti, Luca Reggiani\|Bettelli, Stefania
PMID:	26352110

1275.
Journal:	Int J Colorectal Dis. 2015 Dec;30(12):1653-7.
Title:	Young age of onset colorectal cancers.
Author:	Liang, Jennifer\|Kalady, Matthew F\|Church, James
PMID:	26358068

1276.
Journal:	Cancer Gene Ther. 2015 Sep;22(9):417-30.
Title:	A 2015 update on predictive molecular pathology and its role in targeted cancer therapy: a review focussing on clinical relevance.
Author:	Dietel, M\|Johrens, K\|Laffert, M V\|Hummel, M\|Blaker, H\|Pfitzner, B M\|Lehmann, A\|Denkert, C\|Darb-Esfahani, S\|Lenze, D\|Heppner, F L\|Koch, A\|Sers, C\|Klauschen, F\|Anagnostopoulos, I
PMID:	26358176

1277.
Journal:	In Vivo. 2015 Sep-Oct;29(5):577-84.
Title:	Co-existence of BRAF V600E Gene Mutation in Tumor and Non-tumoral Surrounding Tissues in Colorectal Cancer.
Author:	Ozturk, Tulin\|Toptas-Hekimoglu, Bahar\|Eronat, Allison Pinar\|Saygili, Neslihan\|Daglar-Aday, Aynur\|Bassullu, Nuray\|Turkmen, Ilknur\|Aydogan, Hulya Yilmaz\|Bulbul, Gulen\|Goksel, Suha\|Ozturk, Oguz\|Isbir, Turgay
PMID:	26359417

1278.
Journal:	World J Gastroenterol. 2015 Sep 7;21(33):9749-57.
Title:	Annexin A10 expression in colorectal cancers with emphasis on the serrated neoplasia pathway.
Author:	Bae, Jeong Mo\|Kim, Jung Ho\|Rhee, Ye-Young\|Cho, Nam-Yun\|Kim, Tae-You\|Kang, Gyeong Hoon
PMID:	26361422

1279.
Journal:	Cell Rep. 2015 Sep 29;12(12):1978-85.
Title:	PTPN11 Is a Central Node in Intrinsic and Acquired Resistance to Targeted Cancer Drugs.
Author:	Prahallad, Anirudh\|Heynen, Guus J J E\|Germano, Giovanni\|Willems, Stefan M\|Evers, Bastiaan\|Vecchione, Loredana\|Gambino, Valentina\|Lieftink, Cor\|Beijersbergen, Roderick L\|Di Nicolantonio, Federica\|Bardelli, Alberto\|Bernards, Rene
PMID:	26365186

1280.
Journal:	PLoS One. 2015 Sep 14;10(9):e0138245.
Title:	Clinical Validation of Targeted Next Generation Sequencing for Colon and Lung Cancers.
Author:	D'Haene, Nicky\|Le Mercier, Marie\|De Neve, Nancy\|Blanchard, Oriane\|Delaunoy, Melanie\|El Housni, Hakim\|Dessars, Barbara\|Heimann, Pierre\|Remmelink, Myriam\|Demetter, Pieter\|Tejpar, Sabine\|Salmon, Isabelle
PMID:	26366557

1281.
Journal:	PLoS One. 2015 Sep 16;10(9):e0138141.
Title:	High Prevalence and Clinical Relevance of Genes Affected by Chromosomal Breaks in Colorectal Cancer.
Author:	van den Broek, Evert\|Dijkstra, Maurits J J\|Krijgsman, Oscar\|Sie, Daoud\|Haan, Josien C\|Traets, Joleen J H\|van de Wiel, Mark A\|Nagtegaal, Iris D\|Punt, Cornelis J A\|Carvalho, Beatriz\|Ylstra, Bauke\|Abeln, Sanne\|Meijer, Gerrit A\|Fijneman, Remond J A
PMID:	26375816

1282.
Journal:	Am J Clin Pathol. 2015 Oct;144(4):620-8.
Title:	Non-p.V600E BRAF Mutations Are Common Using a More Sensitive and Broad Detection Tool.
Author:	Carter, Jamal\|Tseng, Li-Hui\|Zheng, Gang\|Dudley, Jonathan\|Illei, Peter\|Gocke, Christopher D\|Eshleman, James R\|Lin, Ming-Tseh
PMID:	26386083

1283.
Journal:	J Clin Oncol. 2015 Dec 1;33(34):4023-31.
Title:	Combined BRAF and MEK Inhibition With Dabrafenib and Trametinib in BRAF V600-Mutant Colorectal Cancer.
Author:	Corcoran, Ryan B\|Atreya, Chloe E\|Falchook, Gerald S\|Kwak, Eunice L\|Ryan, David P\|Bendell, Johanna C\|Hamid, Omid\|Messersmith, Wells A\|Daud, Adil\|Kurzrock, Razelle\|Pierobon, Mariaelena\|Sun, Peng\|Cunningham, Elizabeth\|Little, Shonda\|Orford, Keith\|Motwani, Mo
PMID:	26392102

1284.
Journal:	Biomark Cancer. 2015 Sep 6;7(Suppl 1):9-12.
Title:	BRAF Mutation in Colorectal Cancer: An Update.
Author:	Barras, David
PMID:	26396549

1285.
Journal:	Mod Pathol. 2015 Dec;28(12):1584-93.
Title:	Serrated colorectal polyps in inflammatory bowel disease.
Author:	Ko, Huaibin M\|Harpaz, Noam\|McBride, Russell B\|Cui, Miao\|Ye, Fei\|Zhang, David\|Ullman, Thomas A\|Polydorides, Alexandros D
PMID:	26403785

1286.
Journal:	Int J Mol Sci. 2015 Sep 23;16(9):22976-88.
Title:	Dual Inhibition of MEK and PI3K Pathway in KRAS and BRAF Mutated Colorectal Cancers.
Author:	Temraz, Sally\|Mukherji, Deborah\|Shamseddine, Ali
PMID:	26404261

1287.
Journal:	Am J Clin Nutr. 2015 Nov;102(5):1134-41.
Title:	Postdiagnostic intake of one-carbon nutrients and alcohol in relation to colorectal cancer survival.
Author:	Lochhead, Paul\|Nishihara, Reiko\|Qian, Zhi Rong\|Mima, Kosuke\|Cao, Yin\|Sukawa, Yasutaka\|Kim, Sun A\|Inamura, Kentaro\|Zhang, Xuehong\|Wu, Kana\|Giovannucci, Edward\|Meyerhardt, Jeffrey A\|Chan, Andrew T\|Fuchs, Charles S\|Ogino, Shuji
PMID:	26423386

1288.
Journal:	Oncoscience. 2015 Aug 31;2(8):675-6.
Title:	Cell hierarchies in colorectal cancer: focus on APC and BRAF.
Author:	Morkel, Markus\|Riemer, Pamela
PMID:	26425654

1289.
Journal:	Oncotarget. 2015 Oct 13;6(31):30592-603.
Title:	Rapid targeted somatic mutation analysis of solid tumors in routine clinical diagnostics.
Author:	Magliacane, Gilda\|Grassini, Greta\|Bartocci, Paola\|Francaviglia, Ilaria\|Dal Cin, Elena\|Barbieri, Gianluca\|Arrigoni, Gianluigi\|Pecciarini, Lorenza\|Doglioni, Claudio\|Cangi, Maria Giulia
PMID:	26435479

1290.
Journal:	Mol Cancer Ther. 2015 Dec;14(12):2887-95.
Title:	Assessment of BRAF V600E Status in Colorectal Carcinoma: Tissue-Specific Discordances between Immunohistochemistry and Sequencing.
Author:	Estrella, Jeannelyn S\|Tetzlaff, Michael T\|Bassett, Roland L Jr\|Patel, Keyur P\|Williams, Michelle D\|Curry, Jonathan L\|Rashid, Asif\|Hamilton, Stanley R\|Broaddus, Russell R
PMID:	26438153

1291.
Journal:	Oncotarget. 2015 Oct 27;6(33):34561-72.
Title:	Antitumor activity of a potent MEK inhibitor, TAK-733, against colorectal cancer cell lines and patient derived xenografts.
Author:	Lieu, Christopher H\|Klauck, Peter J\|Henthorn, Patrick K\|Tentler, John J\|Tan, Aik-Choon\|Spreafico, Anna\|Selby, Heather M\|Britt, Blair C\|Bagby, Stacey M\|Arcaroli, John J\|Messersmith, Wells A\|Pitts, Todd M\|Eckhardt, S Gail
PMID:	26439693

1292.
Journal:	Oncologist. 2015 Nov;20(11):1261-5.
Title:	Single-Agent Panitumumab in Frail Elderly Patients With Advanced RAS and BRAF Wild-Type Colorectal Cancer: Challenging Drug Label to Light Up New Hope.
Author:	Pietrantonio, Filippo\|Cremolini, Chiara\|Aprile, Giuseppe\|Lonardi, Sara\|Orlandi, Armando\|Mennitto, Alessia\|Berenato, Rosa\|Antoniotti, Carlotta\|Casagrande, Mariaelena\|Marsico, Valentina\|Marmorino, Federica\|Cardellino, Giovanni Gerardo\|Bergamo, Francesca\|Tom
PMID:	26446234

1293.
Journal:	Curr Cancer Drug Targets. 2015;15(8):703-15.
Title:	Prognostic and Predictive Biomarkers in Colorectal Cancer. From the Preclinical Setting to Clinical Practice.
Author:	Maurel, Joan\|Postigo, Antonio
PMID:	26452385

1294.
Journal:	J Clin Oncol. 2015 Dec 1;33(34):3990-2.
Title:	Hitting the Target in BRAF-Mutant Colorectal Cancer.
Author:	Nagaraja, Ankur K\|Bass, Adam J
PMID:	26460302

1295.
Journal:	J Clin Oncol. 2015 Dec 1;33(34):4032-8.
Title:	Phase II Pilot Study of Vemurafenib in Patients With Metastatic BRAF-Mutated Colorectal Cancer.
Author:	Kopetz, Scott\|Desai, Jayesh\|Chan, Emily\|Hecht, Joel Randolph\|O'Dwyer, Peter J\|Maru, Dipen\|Morris, Van\|Janku, Filip\|Dasari, Arvind\|Chung, Woonbook\|Issa, Jean-Pierre J\|Gibbs, Peter\|James, Brian\|Powis, Garth\|Nolop, Keith B\|Bhattacharya, Suman\|Saltz, Leonard
PMID:	26460303

1296.
Journal:	Adv Clin Exp Med. 2015 Jul-Aug;24(4):555-63.
Title:	Large Bowel Genetic Background and Inflammatory Processes in Carcinogenesis--Systematic Review.
Author:	Szylberg, Lukasz\|Janiczek, Marlena\|Popiel, Aneta\|Marszalek, Andrzej
PMID:	26469098

1297.
Journal:	Carcinogenesis. 2015 Dec;36(12):1502-10.
Title:	Mitochondrial DNA copy number in colorectal cancer: between tissue comparisons, clinicopathological characteristics and survival.
Author:	van Osch, Frits H M\|Voets, An M\|Schouten, Leo J\|Gottschalk, Ralph W H\|Simons, Colinda C J M\|van Engeland, Manon\|Lentjes, Marjolein H F M\|van den Brandt, Piet A\|Smeets, Hubert J M\|Weijenberg, Matty P
PMID:	26476438

1298.
Journal:	Genom Data. 2015 Apr 28;4:158-61.
Title:	Global gene expression profiling analysis reveals reduction of stemness after B-RAF inhibition in colorectal cancer cell lines.
Author:	Boerries, Melanie\|Herr, Ricarda\|Brummer, Tilman\|Busch, Hauke
PMID:	26484206

1299.
Journal:	BMC Cancer. 2015 Oct 20;15:747.
Title:	Exploratory biomarker analysis for treatment response in KRAS wild type metastatic colorectal cancer patients who received cetuximab plus irinotecan.
Author:	Kim, Seung Tae\|Ahn, Tae Jin\|Lee, Eunjin\|Do, In-Gu\|Lee, Su Jin\|Park, Se Hoon\|Park, Joon Oh\|Park, Young Suk\|Lim, Ho Yeong\|Kang, Won Ki\|Kim, Suk Hyeong\|Lee, Jeeyun\|Kim, Hee Cheol
PMID:	26486455

1300.
Journal:	Oncotarget. 2015 Dec 8;6(39):41453-63.
Title:	VE1 immunohistochemistry predicts BRAF V600E mutation status and clinical outcome in colorectal cancer.
Author:	Schafroth, Christian\|Galvan, Jose A\|Centeno, Irene\|Koelzer, Viktor H\|Dawson, Heather E\|Sokol, Lena\|Rieger, Gregor\|Berger, Martin D\|Hadrich, Marion\|Rosenberg, Robert\|Nitsche, Ulrich\|Schnuriger, Beat\|Langer, Rupert\|Inderbitzin, Daniel\|Lugli, Alessandro\|Zlob
PMID:	26496026

1301.
Journal:	BMC Cancer. 2015 Oct 24;15:779.
Title:	Clinical detection and categorization of uncommon and concomitant mutations involving BRAF.
Author:	Zheng, Gang\|Tseng, Li-Hui\|Chen, Guoli\|Haley, Lisa\|Illei, Peter\|Gocke, Christopher D\|Eshleman, James R\|Lin, Ming-Tseh
PMID:	26498038

1302.
Journal:	Zhonghua Wei Chang Wai Ke Za Zhi. 2015 Oct;18(10):994-7.
Title:	[Molecular phenotypes of colorectal cancer is critical in clinical individual treatment].
Author:	Deng, Yanhong
PMID:	26499143

1303.
Journal:	BMC Cancer. 2015 Oct 27;15:808.
Title:	Prediction of response to anti-EGFR antibody-based therapies by multigene sequencing in colorectal cancer patients.
Author:	Lupini, Laura\|Bassi, Cristian\|Mlcochova, Jitka\|Musa, Gentian\|Russo, Marta\|Vychytilova-Faltejskova, Petra\|Svoboda, Marek\|Sabbioni, Silvia\|Nemecek, Radim\|Slaby, Ondrej\|Negrini, Massimo
PMID:	26508446

1304.
Journal:	Onco Targets Ther. 2015 Oct 15;8:2949-57.
Title:	Molecular profiling in the treatment of colorectal cancer: focus on regorafenib.
Author:	Yan, Yiyi\|Grothey, Axel
PMID:	26508880

1305.
Journal:	Oncotarget. 2015 Dec 8;6(39):42334-44.
Title:	Mutational profiling of colorectal cancers with microsatellite instability.
Author:	Lin, Elaine I\|Tseng, Li-Hui\|Gocke, Christopher D\|Reil, Stacy\|Le, Dung T\|Azad, Nilofer S\|Eshleman, James R
PMID:	26517354

1306.
Journal:	Cytogenet Genome Res. 2015;146(4):261-7.
Title:	Colorectal Cancers with the Uncommon Findings of KRAS Mutation and Microsatellite Instability.
Author:	Zauber, Peter\|Marotta, Stephen\|Sabbath-Solitare, Marlene
PMID:	26523369

1307.
Journal:	J Clin Oncol. 2015 Dec 10;33(35):4176-87.
Title:	Adjuvant Fluorouracil, Leucovorin, and Oxaliplatin in Stage II to III Colon Cancer: Updated 10-Year Survival and Outcomes According to BRAF Mutation and Mismatch Repair Status of the MOSAIC Study.
Author:	Andre, Thierry\|de Gramont, Armand\|Vernerey, Dewi\|Chibaudel, Benoist\|Bonnetain, Franck\|Tijeras-Raballand, Annemilai\|Scriva, Aurelie\|Hickish, Tamas\|Tabernero, Josep\|Van Laethem, Jean Luc\|Banzi, Maria\|Maartense, Eduard\|Shmueli, Einat\|Carlsson, Goran U\|Scheit
PMID:	26527776

1308.
Journal:	Oncotarget. 2015 Nov 24;6(37):39607-13.
Title:	Molecular pathological epidemiology of colorectal cancer in Chinese patients with KRAS and BRAF mutations.
Author:	Li, Wenbin\|Qiu, Tian\|Ling, Yun\|Guo, Lei\|Li, Lin\|Ying, Jianming
PMID:	26530529

1309.
Journal:	Science. 2015 Dec 11;350(6266):1391-6.
Title:	Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH.
Author:	Yun, Jihye\|Mullarky, Edouard\|Lu, Changyuan\|Bosch, Kaitlyn N\|Kavalier, Adam\|Rivera, Keith\|Roper, Jatin\|Chio, Iok In Christine\|Giannopoulou, Eugenia G\|Rago, Carlo\|Muley, Ashlesha\|Asara, John M\|Paik, Jihye\|Elemento, Olivier\|Chen, Zhengming\|Pappin, Darryl J\|D
PMID:	26541605

1310.
Journal:	BMC Cancer. 2015 Nov 9;15:874.
Title:	Molecular and pathological characterization of the EZH2 rs3757441 single nucleotide polymorphism in colorectal cancer.
Author:	Fornaro, Lorenzo\|Faviana, Pinuccia\|De Gregorio, Veronica\|Vivaldi, Caterina\|Paolicchi, Elisa\|Masi, Gianluca\|Loupakis, Fotios\|Sensi, Elisa\|Lupi, Cristiana\|Fontanini, Gabriella\|Wang, Yuzhuo\|Danesi, Romano\|Falcone, Alfredo\|Crea, Francesco
PMID:	26553291

1311.
Journal:	Cancer Biol Ther. 2015;16(12):1726-37.
Title:	Molecular profiling of 6,892 colorectal cancer samples suggests different possible treatment options specific to metastatic sites.
Author:	El-Deiry, Wafik S\|Vijayvergia, Namrata\|Xiu, Joanne\|Scicchitano, Angelique\|Lim, Bora\|Yee, Nelson S\|Harvey, Harold A\|Gatalica, Zoran\|Reddy, Sandeep
PMID:	26553611

1312.
Journal:	Gastroenterol Res Pract. 2015;2015:132190.
Title:	Molecular Features and Methylation Status in Early Onset (
Author:	Magnani, Giulia\|Furlan, Daniela\|Sahnane, Nora\|Reggiani Bonetti, Luca\|Domati, Federica\|Pedroni, Monica
PMID:	26557847

1313.
Journal:	Cancer Biol Ther. 2015;16(12):1710-9.
Title:	Regorafenib with a fluoropyrimidine for metastatic colorectal cancer after progression on multiple 5-FU-containing combination therapies and regorafenib monotherapy.
Author:	Marks, Eric I\|Tan, Carlyn\|Zhang, Jun\|Zhou, Lanlan\|Yang, Zhaohai\|Scicchitano, Angelique\|El-Deiry, Wafik S
PMID:	26561209

1314.
Journal:	Expert Opin Drug Metab Toxicol. 2015;11(12):1907-24.
Title:	Pharmacokinetic and pharmacodynamic evaluation of panitumumab in the treatment of colorectal cancer.
Author:	Lo, Louisa\|Patel, Dainik\|Townsend, Amanda R\|Price, Timothy J
PMID:	26572750

1315.
Journal:	J Dig Cancer Rep. 2015 Jun;3(1):5-10.
Title:	Biomarker-directed Targeted Therapy in Colorectal Cancer.
Author:	Carethers, John M
PMID:	26609516

1316.
Journal:	Semin Oncol. 2015 Dec;42(6):896-908.
Title:	Overcoming Resistance to Targeted Therapies in Cancer.
Author:	Redmond, Keara L\|Papafili, Anastasia\|Lawler, Mark\|Van Schaeybroeck, Sandra
PMID:	26615134

1317.
Journal:	Pharmacogenomics. 2015 Dec;16(18):2069-81.
Title:	BRAF in metastatic colorectal cancer: the future starts now.
Author:	Orlandi, Armando\|Calegari, Alessandra\|Inno, Alessandro\|Berenato, Rosa\|Caporale, Marta\|Niger, Monica\|Bossi, Ilaria\|Di Bartolomeo, Maria\|de Braud, Filippo\|Pietrantonio, Filippo
PMID:	26615988

1318.
Journal:	Curr Colorectal Cancer Rep. 2015;11(6):335-344.
Title:	Treatment Individualization in Colorectal Cancer.
Author:	van Geel, Robin M J M\|Beijnen, Jos H\|Bernards, Rene\|Schellens, Jan H M
PMID:	26617477

1319.
Journal:	Pol J Pathol. 2015 Sep;66(3):203-18.
Title:	Microsatellite instability in colorectal cancer: clinicopathological significance.
Author:	Setaffy, Lisa\|Langner, Cord
PMID:	26619098

1320.
Journal:	Oncol Lett. 2015 Sep;10(3):1423-1429.
Title:	Mutation of the PIK3CA gene as a prognostic factor in patients with colorectal cancer.
Author:	Stec, Rafal\|Semeniuk-Wojtas, Aleksandra\|Charkiewicz, Radoslaw\|Bodnar, Lubomir\|Korniluk, Jan\|Smoter, Marta\|Chyczewski, Lech\|Niklinski, Jacek\|Szczylik, Cezary
PMID:	26622684

1321.
Journal:	Clin Epigenetics. 2015 Dec 2;7:124.
Title:	Epigenetic inactivation of the extracellular matrix metallopeptidase ADAMTS19 gene and the metastatic spread in colorectal cancer.
Author:	Alonso, Sergio\|Gonzalez, Beatriz\|Ruiz-Larroya, Tatiana\|Duran Dominguez, Mercedes\|Kato, Takaharu\|Matsunaga, Akihiro\|Suzuki, Koichi\|Strongin, Alex Y\|Gimenez-Bonafe, Pepita\|Perucho, Manuel
PMID:	26634009

1322.
Journal:	Onco Targets Ther. 2015 Dec 1;8:3561-4.
Title:	A metastatic colon adenocarcinoma harboring BRAF V600E has a durable major response to dabrafenib/trametinib and chemotherapy.
Author:	Williams, Casey B\|McMahon, Caitlin\|Ali, Siraj M\|Abramovitz, Mark\|Williams, Kirstin A\|Klein, Jessica\|McKean, Heidi\|Yelensky, Roman\|George, Thomas J Jr\|Elvin, Julia A\|Soman, Salil\|Lipson, Doron\|Chmielecki, Juliann\|Morosini, Deborah\|Miller, Vincent A\|Stephen
PMID:	26664139

1323.
Journal:	Genet Mol Res. 2015 Dec 14;14(4):16793-802.
Title:	Mutation profile of KRAS and BRAF genes in patients with colorectal cancer: association with morphological and prognostic criteria.
Author:	Samara, M\|Kapatou, K\|Ioannou, M\|Kostopoulou, Epsilon\|Papamichali, R\|Papandreou, C\|Athanasiadis, A\|Koukoulis, G
PMID:	26681025

1324.
Journal:	Sci Rep. 2015 Dec 22;5:18678.
Title:	Molecular spectrum of KRAS, NRAS, BRAF and PIK3CA mutations in Chinese colorectal cancer patients: analysis of 1,110 cases.
Author:	Zhang, Jing\|Zheng, Jianming\|Yang, Yinghong\|Lu, Junliang\|Gao, Jie\|Lu, Tao\|Sun, Jian\|Jiang, Hui\|Zhu, Yan\|Zheng, Yuhui\|Liang, Zhiyong\|Liu, Tonghua
PMID:	26691448

1325.
Journal:	Clin Epigenetics. 2015 Dec 21;7:131.
Title:	Aberrant DNA methylation profiles of inherited and sporadic colorectal cancer.
Author:	Sahnane, Nora\|Magnoli, Francesca\|Bernasconi, Barbara\|Tibiletti, Maria Grazia\|Romualdi, Chiara\|Pedroni, Monica\|Ponz de Leon, Maurizio\|Magnani, Giulia\|Reggiani-Bonetti, Luca\|Bertario, Lucio\|Signoroni, Stefano\|Capella, Carlo\|Sessa, Fausto\|Furlan, Daniela
PMID:	26697123

1326.
Journal:	J Gastrointest Oncol. 2015 Dec;6(6):628-37.
Title:	Proficiency of DNA repair genes and microsatellite instability in operated colorectal cancer patients with clinical suspicion of lynch syndrome.
Author:	de Freitas, Isabella Nicacio\|de Campos, Fabio Guilherm Caserta Maryssael\|Alves, Venancio Avancini Ferreira\|Cavalcante, Juliana Magalhaes\|Carraro, Dirce\|Coudry, Renata de Almeida\|Diniz, Marcio Augusto\|Nahas, Sergio Carlos\|Ribeiro, Ulysses Jr
PMID:	26697194

1327.
Journal:	J Gastrointest Oncol. 2015 Dec;6(6):645-9.
Title:	Impact of somatic mutations on patterns of metastasis in colorectal cancer.
Author:	Lipsyc, Marla\|Yaeger, Rona
PMID:	26697197

1328.
Journal:	J Gastrointest Oncol. 2015 Dec;6(6):650-9.
Title:	New therapeutic strategies for BRAF mutant colorectal cancers.
Author:	Corcoran, Ryan B
PMID:	26697198

1329.
Journal:	J Gastrointest Oncol. 2015 Dec;6(6):660-7.
Title:	BRAF mutant colorectal cancer as a distinct subset of colorectal cancer: clinical characteristics, clinical behavior, and response to targeted therapies.
Author:	Clarke, Callisia N\|Kopetz, E Scott
PMID:	26697199

1330.
Journal:	J Gastrointest Oncol. 2015 Dec;6(6):676-84.
Title:	Implications of mismatch repair-deficient status on management of early stage colorectal cancer.
Author:	Kawakami, Hisato\|Zaanan, Aziz\|Sinicrope, Frank A
PMID:	26697201

1331.
Journal:	J Gastrointest Oncol. 2015 Dec;6(6):699-708.
Title:	Hepatic resection, hepatic arterial infusion pump therapy, and genetic biomarkers in the management of hepatic metastases from colorectal cancer.
Author:	McAuliffe, John C\|Qadan, Motaz\|D'Angelica, Michael I
PMID:	26697204

1332.
Journal:	BMC Cancer. 2015 Dec 29;15:1020.
Title:	A kinome siRNA screen identifies HGS as a potential target for liver cancers with oncogenic mutations in CTNNB1.
Author:	Canal, Frederic\|Anthony, Elodie\|Lescure, Aurianne\|Del Nery, Elaine\|Camonis, Jacques\|Perez, Franck\|Ragazzon, Bruno\|Perret, Christine
PMID:	26715116

1333.
Journal:	Gan To Kagaku Ryoho. 2015 Nov;42(12):2215-7.
Title:	[A Case of Serrated Polyposis Syndrome with Early Colon Cancer].
Author:	Suzuki, Okihide\|Chika, Noriyasu\|Tachikawa, Tetsuhiko\|Aoyagi, Nobuhiko\|Eguchi, Hidetaka\|Kumamoto, Kensuke\|Mochiki, Erito\|Miura, Ichiro\|Yao, Takashi\|Ishida, Hideyuki
PMID:	26805315

1334.
Journal:	Mol Cell Oncol. 2015 Jan 23;2(4):e1002709.
Title:	BRAF inhibitors in colorectal cancer: Toward a differentiation therapy?
Author:	Herr, Ricarda\|Brummer, Tilman
PMID:	27308494

1335.
Journal:	Am J Clin Oncol. 2016 Jun;39(3):236-42.
Title:	Phase II Trial of Target-guided Personalized Chemotherapy in First-line Metastatic Colorectal Cancer.
Author:	Cubillo, Antonio\|Rodriguez-Pascual, Jesus\|Lopez-Rios, Fernando\|Plaza, Carlos\|Garcia, Elena\|Alvarez, Rafael\|de Vicente, Emilio\|Quijano, Yolanda\|Hernando, Ovidio\|Rubio, Carmen\|Perea, Sofia\|Sanchez, Gema\|Hidalgo, Manuel
PMID:	24517959

1336.
Journal:	Appl Immunohistochem Mol Morphol. 2016 Feb;24(2):88-96.
Title:	BRAFV600E Gene Mutation in Colonic Adenocarcinomas. Immunohistochemical Detection Using Tissue Microarray and Clinicopathologic Characteristics: An 86 Case Series.
Author:	Boulagnon, Camille\|Dudez, Oriane\|Beaudoux, Olivia\|Dalstein, Veronique\|Kianmanesh, Reza\|Bouche, Olivier\|Diebold, Marie-Daniele
PMID:	25710585

1337.
Journal:	Gut. 2016 Aug;65(8):1296-305.
Title:	Activating ERBB2/HER2 mutations indicate susceptibility to pan-HER inhibitors in Lynch and Lynch-like colorectal cancer.
Author:	Kloth, Michael\|Ruesseler, Vanessa\|Engel, Christoph\|Koenig, Katharina\|Peifer, Martin\|Mariotti, Erika\|Kuenstlinger, Helen\|Florin, Alexandra\|Rommerscheidt-Fuss, Ursula\|Koitzsch, Ulrike\|Wodtke, Claudia\|Ueckeroth, Frank\|Holzapfel, Stefanie\|Aretz, Stefan\|Proppi
PMID:	26001389

1338.
Journal:	Histopathology. 2016 Mar;68(4):578-87.
Title:	Serrated tubulovillous adenoma of the large intestine.
Author:	Bettington, Mark\|Walker, Neal\|Rosty, Christophe\|Brown, Ian\|Clouston, Andrew\|McKeone, Diane\|Pearson, Sally-Ann\|Klein, Kerenaftali\|Leggett, Barbara\|Whitehall, Vicki
PMID:	26212352

1339.
Journal:	Surg Today. 2016 Jun;46(6):713-20.
Title:	Lower prevalence of Lynch syndrome in colorectal cancer patients in a Japanese hospital-based population.
Author:	Kumamoto, Kensuke\|Ishida, Hideyuki\|Suzuki, Okihide\|Tajima, Yusuke\|Chika, Noriyasu\|Kuwabara, Koki\|Ishibashi, Keiichiro\|Saito, Katsuharu\|Nagata, Koji\|Eguchi, Hidetaka\|Tamaru, Junichi\|Iwama, Takeo
PMID:	26249337

1340.
Journal:	J Clin Pathol. 2016 Mar;69(3):204-8.
Title:	Correlation between DPYD gene variation and KRAS wild type status in colorectal cancer.
Author:	Kleist, Britta\|Kempa, Marcel\|Meurer, Thuja\|Poetsch, Micaela
PMID:	26281864

1341.
Journal:	Gut. 2016 Dec;65(12):1973-1980.
Title:	Fusobacterium nucleatum in colorectal carcinoma tissue and patient prognosis.
Author:	Mima, Kosuke\|Nishihara, Reiko\|Qian, Zhi Rong\|Cao, Yin\|Sukawa, Yasutaka\|Nowak, Jonathan A\|Yang, Juhong\|Dou, Ruoxu\|Masugi, Yohei\|Song, Mingyang\|Kostic, Aleksandar D\|Giannakis, Marios\|Bullman, Susan\|Milner, Danny A\|Baba, Hideo\|Giovannucci, Edward L\|Garraway,
PMID:	26311717

1342.
Journal:	Int J Cancer. 2016 Feb 15;138(4):881-90.
Title:	The distribution of BRAF gene fusions in solid tumors and response to targeted therapy.
Author:	Ross, Jeffrey S\|Wang, Kai\|Chmielecki, Juliann\|Gay, Laurie\|Johnson, Adrienne\|Chudnovsky, Jacob\|Yelensky, Roman\|Lipson, Doron\|Ali, Siraj M\|Elvin, Julia A\|Vergilio, Jo-Anne\|Roels, Steven\|Miller, Vincent A\|Nakamura, Brooke N\|Gray, Adam\|Wong, Michael K\|Stephen
PMID:	26314551

1343.
Journal:	J Clin Pathol. 2016 Jan;69(1):35-41.
Title:	Pre-trial inter-laboratory analytical validation of the FOCUS4 personalised therapy trial.
Author:	Richman, Susan D\|Adams, Richard\|Quirke, Phil\|Butler, Rachel\|Hemmings, Gemma\|Chambers, Phil\|Roberts, Helen\|James, Michelle D\|Wozniak, Sue\|Bathia, Riya\|Pugh, Cheryl\|Maughan, Timothy\|Jasani, Bharat
PMID:	26350752

1344.
Journal:	Clin Cancer Res. 2016 Jan 15;22(2):405-14.
Title:	Sensitivity of KRAS-Mutant Colorectal Cancers to Combination Therapy That Cotargets MEK and CDK4/6.
Author:	Ziemke, Elizabeth K\|Dosch, Joseph S\|Maust, Joel D\|Shettigar, Amrith\|Sen, Ananda\|Welling, Theodore H\|Hardiman, Karin M\|Sebolt-Leopold, Judith S
PMID:	26369631

1345.
Journal:	Int J Cancer. 2016 Mar 1;138(5):1139-45.
Title:	Prognostic value of BRAF and KRAS mutation status in stage II and III microsatellite instable colon cancers.
Author:	de Cuba, E M V\|Snaebjornsson, P\|Heideman, D A M\|van Grieken, N C T\|Bosch, L J W\|Fijneman, R J A\|Belt, E\|Bril, H\|Stockmann, H B A C\|Hooijberg, E\|Punt, C J A\|Koopman, M\|Nagtegaal, I D\|Coupe, V H M\|Carvalho, B\|Meijer, G A
PMID:	26376292

1346.
Journal:	J Cell Physiol. 2016 May;231(5):1097-105.
Title:	Involvement of Notch-1 in Resistance to Regorafenib in Colon Cancer Cells.
Author:	Mirone, Giovanna\|Perna, Stefania\|Shukla, Arvind\|Marfe, Gabriella
PMID:	26419617

1347.
Journal:	Cancer Immunol Res. 2016 Jan;4(1):33-40.
Title:	MicroRNA MIR21 and T Cells in Colorectal Cancer.
Author:	Mima, Kosuke\|Nishihara, Reiko\|Nowak, Jonathan A\|Kim, Sun A\|Song, Mingyang\|Inamura, Kentaro\|Sukawa, Yasutaka\|Masuda, Atsuhiro\|Yang, Juhong\|Dou, Ruoxu\|Nosho, Katsuhiko\|Baba, Hideo\|Giovannucci, Edward L\|Bowden, Michaela\|Loda, Massimo\|Giannakis, Marios\|Bass,
PMID:	26419959

1348.
Journal:	Tumour Biol. 2016 Mar;37(3):3571-80.
Title:	Clinical influence of cancer stem cells on residual disease after preoperative chemoradiotherapy for rectal cancer.
Author:	Yoon, Ghilsuk\|Kim, Sol-Min\|Kim, Hye Jin\|Seo, An Na
PMID:	26456957

1349.
Journal:	Ann Surg Oncol. 2016 Mar;23(3):849-55.
Title:	Mutation Spectra of Common Cancer-Associated Genes in Different Phenotypes of Colorectal Carcinoma Without Distant Metastasis.
Author:	Chang, Shih-Ching\|Lin, Pei-Ching\|Lin, Jen-Kou\|Lin, Chien-Hsing\|Yang, Shung-Haur\|Liang, Wen-Yi\|Chen, Wei-Shone\|Jiang, Jeng-Kai
PMID:	26471487

1350.
Journal:	Int J Cancer. 2016 Mar 15;138(6):1472-81.
Title:	The serrated neoplasia pathway of colorectal tumors: Identification of MUC5AC hypomethylation as an early marker of polyps with malignant potential.
Author:	Renaud, Florence\|Mariette, Christophe\|Vincent, Audrey\|Wacrenier, Agnes\|Maunoury, Vincent\|Leclerc, Julie\|Coppin, Lucie\|Crepin, Michel\|Van Seuningen, Isabelle\|Leteurtre, Emmanuelle\|Buisine, Marie-Pierre
PMID:	26476272

1351.
Journal:	Clin Cancer Res. 2016 Mar 15;22(6):1489-98.
Title:	Prognostic Utility of Molecular Factors by Age at Diagnosis of Colorectal Cancer.
Author:	McCleary, Nadine J\|Sato, Kaori\|Nishihara, Reiko\|Inamura, Kentaro\|Morikawa, Teppei\|Zhang, Xuehong\|Wu, Kana\|Yamauchi, Mai\|Kim, Sun A\|Sukawa, Yasutaka\|Mima, Kosuke\|Qian, Zhi Rong\|Fuchs, Charles S\|Ogino, Shuji\|Meyerhardt, Jeffrey A
PMID:	26490308

1352.
Journal:	Histopathology. 2016 May;68(6):810-8.
Title:	Traditional serrated adenoma with BRAF mutation is associated with synchronous/metachronous BRAF-mutated serrated lesions.
Author:	Tsai, Jia-Huei\|Cheng, Chien-Hsuan\|Chen, Chien-Chuan\|Lin, Yu-Lin\|Lin, Liang-In\|Chen, Mei-Ling\|Liau, Jau-Yu
PMID:	26496853

1353.
Journal:	Oncol Rep. 2016 Jan;35(1):107-16.
Title:	Lauric acid can improve the sensitization of Cetuximab in KRAS/BRAF mutated colorectal cancer cells by retrievable microRNA-378 expression.
Author:	Weng, Wen-Hui\|Leung, Wai-Hung\|Pang, Yeu-Jye\|Hsu, Hsi-Hsien
PMID:	26496897

1354.
Journal:	J Clin Pathol. 2016 Apr;69(4):319-25.
Title:	Frequent BRAF mutation in early-onset colorectal cancer in Taiwan: association with distinct clinicopathological and molecular features and poor clinical outcome.
Author:	Tsai, Jia-Huei\|Liau, Jau-Yu\|Lin, Yu-Lin\|Tseng, Li-Hui\|Lin, Liang-In\|Yeh, Kun-Huei\|Jeng, Yung-Ming
PMID:	26500331

1355.
Journal:	Int J Cancer. 2016 Apr 1;138(7):1634-44.
Title:	Genetic and epigenetic aberrations occurring in colorectal tumors associated with serrated pathway.
Author:	Sakai, Eiji\|Fukuyo, Masaki\|Ohata, Ken\|Matsusaka, Keisuke\|Doi, Noriteru\|Mano, Yasunobu\|Takane, Kiyoko\|Abe, Hiroyuki\|Yagi, Koichi\|Matsuhashi, Nobuyuki\|Fukushima, Junichi\|Fukayama, Masashi\|Akagi, Kiwamu\|Aburatani, Hiroyuki\|Nakajima, Atsushi\|Kaneda, Atsushi
PMID:	26510091

1356.
Journal:	Cancer Epidemiol Biomarkers Prev. 2016 Jan;25(1):68-75.
Title:	Clinicopathologic Risk Factor Distributions for MLH1 Promoter Region Methylation in CIMP-Positive Tumors.
Author:	Levine, A Joan\|Phipps, Amanda I\|Baron, John A\|Buchanan, Daniel D\|Ahnen, Dennis J\|Cohen, Stacey A\|Lindor, Noralane M\|Newcomb, Polly A\|Rosty, Christophe\|Haile, Robert W\|Laird, Peter W\|Weisenberger, Daniel J
PMID:	26512054

1357.
Journal:	Oncotarget. 2016 Jan 12;7(2):1311-22.
Title:	NDRG4 stratifies the prognostic value of body mass index in colorectal cancer.
Author:	Zheng, Jianyong\|Li, Yunming\|Zhu, Shaojun\|Li, Jipeng\|Zhao, Qingchuan\|Ji, Gang\|Wang, Weizhong\|Chu, Dake
PMID:	26515606

1358.
Journal:	Arch Pathol Lab Med. 2016 Jun;140(6):529-35.
Title:	Next-Generation Sequencing of Matched Primary and Metastatic Rectal Adenocarcinomas Demonstrates Minimal Mutation Gain and Concordance to Colonic Adenocarcinomas.
Author:	Crumley, Suzanne M\|Pepper, Kristi L\|Phan, Alexandria T\|Olsen, Randall J\|Schwartz, Mary R\|Portier, Bryce P
PMID:	26536055

1359.
Journal:	J Clin Pathol. 2016 May;69(5):398-402.
Title:	Automated PCR detection of BRAF mutations in colorectal adenocarcinoma: a diagnostic test accuracy study.
Author:	Colling, Richard\|Wang, Lai Mun\|Soilleux, Elizabeth
PMID:	26537294

1360.
Journal:	Target Oncol. 2016 Jun;11(3):337-43.
Title:	Dose-Dense Temozolomide in Patients with MGMT-Silenced Chemorefractory Colorectal Cancer.
Author:	Pietrantonio, Filippo\|de Braud, Filippo\|Milione, Massimo\|Maggi, Claudia\|Iacovelli, Roberto\|Dotti, Katia Fiorella\|Perrone, Federica\|Tamborini, Elena\|Caporale, Marta\|Berenato, Rosa\|Leone, Giorgia\|Pellegrinelli, Alessio\|Bossi, Ilaria\|Festinese, Fabrizio\|Fede
PMID:	26538496

1361.
Journal:	Nat Rev Clin Oncol. 2016 Jan;13(1):4.
Title:	Colorectal cancer: Targeting BRAF mutations equally?
Author:	Hutchinson, Lisa
PMID:	26552951

1362.
Journal:	Ann Surg Oncol. 2016 Mar;23(3):908-17.
Title:	Survival Benefit of Exercise Differs by Tumor IRS1 Expression Status in Colorectal Cancer.
Author:	Hanyuda, Akiko\|Kim, Sun A\|Martinez-Fernandez, Alejandro\|Qian, Zhi Rong\|Yamauchi, Mai\|Nishihara, Reiko\|Morikawa, Teppei\|Liao, Xiaoyun\|Inamura, Kentaro\|Mima, Kosuke\|Cao, Yin\|Zhang, Xuehong\|Wu, Kana\|Chan, Andrew T\|Giovannucci, Edward L\|Meyerhardt, Jeffrey A\|
PMID:	26577117

1363.
Journal:	Histopathology. 2016 Jul;69(1):54-62.
Title:	Immunohistochemical detection of the BRAF V600E mutant protein in colorectal cancers in Taiwan is highly concordant with the molecular test.
Author:	Hang, Jen-Fan\|Li, Anna Fen-Yau\|Chang, Shih-Ching\|Liang, Wen-Yih
PMID:	26588428

1364.
Journal:	J Natl Cancer Inst. 2015 Nov 23;108(4). pii: djv363.
Title:	Prediagnosis Plasma Adiponectin in Relation to Colorectal Cancer Risk According to KRAS Mutation Status.
Author:	Inamura, Kentaro\|Song, Mingyang\|Jung, Seungyoun\|Nishihara, Reiko\|Yamauchi, Mai\|Lochhead, Paul\|Qian, Zhi Rong\|Kim, Sun A\|Mima, Kosuke\|Sukawa, Yasutaka\|Masuda, Atsuhiro\|Imamura, Yu\|Zhang, Xuehong\|Pollak, Michael N\|Mantzoros, Christos S\|Harris, Curtis C\|Giov
PMID:	26598515

1365.
Journal:	Future Oncol. 2016 Jan;12(1):25-30.
Title:	Targeting BRAF aberrations in advanced colorectal carcinoma: from bench to bedside.
Author:	Abdel-Rahman, Omar
PMID:	26616508

1366.
Journal:	Clin Oncol (R Coll Radiol). 2016 Feb;28(2):73-82.
Title:	Molecular Taxonomy and Tumourigenesis of Colorectal Cancer.
Author:	Biswas, S\|Holyoake, D\|Maughan, T S
PMID:	26631427

1367.
Journal:	Virchows Arch. 2016 Mar;468(3):313-9.
Title:	Microsatellite instability in pulmonary adenocarcinomas: a comprehensive study of 480 cases.
Author:	Warth, Arne\|Korner, Sandrina\|Penzel, Roland\|Muley, Thomas\|Dienemann, Hendrik\|Schirmacher, Peter\|von Knebel-Doeberitz, Magnus\|Weichert, Wilko\|Kloor, Matthias
PMID:	26637197

1368.
Journal:	Clin Cancer Res. 2016 May 15;22(10):2368-76.
Title:	A Phase I Study of the Safety, Pharmacokinetics, and Pharmacodynamics of Combination Therapy with Refametinib plus Sorafenib in Patients with Advanced Cancer.
Author:	Adjei, Alex A\|Richards, Donald A\|El-Khoueiry, Anthony\|Braiteh, Fadi\|Becerra, Carlos H R\|Stephenson, Joe J Jr\|Hezel, Aram F\|Sherman, Morris\|Garbo, Lawrence\|Leffingwell, Diane P\|Iverson, Cory\|Miner, Jeffrey N\|Shen, Zancong\|Yeh, Li-Tain\|Gunawan, Sonny\|Wilson
PMID:	26644411

1369.
Journal:	J Pathol. 2016 Mar;238(4):562-70.
Title:	HER2 overexpression and amplification as a potential therapeutic target in colorectal cancer: analysis of 3256 patients enrolled in the QUASAR, FOCUS and PICCOLO colorectal cancer trials.
Author:	Richman, Susan D\|Southward, Katie\|Chambers, Philip\|Cross, Debra\|Barrett, Jennifer\|Hemmings, Gemma\|Taylor, Morag\|Wood, Henry\|Hutchins, Gordon\|Foster, Joseph M\|Oumie, Assa\|Spink, Karen G\|Brown, Sarah R\|Jones, Marc\|Kerr, David\|Handley, Kelly\|Gray, Richard\|Se
PMID:	26690310

1370.
Journal:	Clin Colorectal Cancer. 2016 Jun;15(2):164-9.
Title:	Evaluation of CpG Island Methylator Phenotype as a Biomarker in Colorectal Cancer Treated With Adjuvant Oxaliplatin.
Author:	Cohen, Stacey A\|Wu, Chen\|Yu, Ming\|Gourgioti, Georgia\|Wirtz, Ralph\|Raptou, Georgia\|Gkakou, Chryssa\|Kotoula, Vassiliki\|Pentheroudakis, George\|Papaxoinis, George\|Karavasilis, Vasilios\|Pectasides, Dimitrios\|Kalogeras, Konstantine T\|Fountzilas, George\|Grady, W
PMID:	26702772

1371.
Journal:	Crit Rev Oncol Hematol. 2016 Mar;99:74-80.
Title:	Methylator phenotype in colorectal cancer: A prognostic factor or not?
Author:	Gallois, C\|Laurent-Puig, P\|Taieb, J
PMID:	26702883

1372.
Journal:	Mol Diagn Ther. 2016 Feb;20(1):75-82.
Title:	BRAF Mutation Testing and Metastatic Colorectal Cancer in the Community Setting: Is There an Urgent Need for More Education?
Author:	Price, Timothy J\|Beeke, Carol\|Townsend, Amanda Rose\|Lo, Louisa\|Amitesh, Roy\|Padbury, Robert\|Roder, David\|Maddern, Guy\|Moore, James\|Karapetis, Christos
PMID:	26714964

1373.
Journal:	Cancer Med. 2016 Feb;5(2):256-64.
Title:	KRAS mutation in lung metastases from colorectal cancer: prognostic implications.
Author:	Ghidini, Michele\|Personeni, Nicola\|Bozzarelli, Silvia\|Baretti, Marina\|Basso, Gianluca\|Bianchi, Paolo\|Tronconi, Maria Chiara\|Pressiani, Tiziana\|Grizzi, Fabio\|Giordano, Laura\|Malesci, Alberto\|Alloisio, Marco\|Laghi, Luigi\|Santoro, Armando\|Rimassa, Lorenza
PMID:	26715198

1374.
Journal:	Br J Cancer. 2016 Jan 19;114(2):199-206.
Title:	Loss of CDH1 (E-cadherin) expression is associated with infiltrative tumour growth and lymph node metastasis.
Author:	Kim, Sun A\|Inamura, Kentaro\|Yamauchi, Mai\|Nishihara, Reiko\|Mima, Kosuke\|Sukawa, Yasutaka\|Li, Tingting\|Yasunari, Mika\|Morikawa, Teppei\|Fitzgerald, Kathryn C\|Fuchs, Charles S\|Wu, Kana\|Chan, Andrew T\|Zhang, Xuehong\|Ogino, Shuji\|Qian, Zhi Rong
PMID:	26742007

1375.
Journal:	Sci Rep. 2016 Jan 11;6:18949.
Title:	BRAF V600E inhibition stimulates AMP-activated protein kinase-mediated autophagy in colorectal cancer cells.
Author:	Sueda, Toshinori\|Sakai, Daisuke\|Kawamoto, Koichi\|Konno, Masamitsu\|Nishida, Naohiro\|Koseki, Jun\|Colvin, Hugh\|Takahashi, Hidekazu\|Haraguchi, Naotsugu\|Nishimura, Junichi\|Hata, Taishi\|Takemasa, Ichiro\|Mizushima, Tsunekazu\|Yamamoto, Hirofumi\|Satoh, Taroh\|Doki,
PMID:	26750638

1376.
Journal:	Gastroenterology. 2016 Apr;150(4):944-55.
Title:	Microsatellite Alterations With Allelic Loss at 9p24.2 Signify Less-Aggressive Colorectal Cancer Metastasis.
Author:	Koi, Minoru\|Garcia, Melissa\|Choi, Chan\|Kim, Hyeong-Rok\|Koike, Junichi\|Hemmi, Hiromichi\|Nagasaka, Takeshi\|Okugawa, Yoshinaga\|Toiyama, Yuji\|Kitajima, Takahito\|Imaoka, Hiroki\|Kusunoki, Masato\|Chen, Yin-Hsiu\|Mukherjee, Bhramar\|Boland, C Richard\|Carethers, Joh
PMID:	26752111

1377.
Journal:	J Mol Diagn. 2016 Mar;18(2):190-204.
Title:	Quantitative Detection and Resolution of BRAF V600 Status in Colorectal Cancer Using Droplet Digital PCR and a Novel Wild-Type Negative Assay.
Author:	Bidshahri, Roza\|Attali, Dean\|Fakhfakh, Kareem\|McNeil, Kelly\|Karsan, Aly\|Won, Jennifer R\|Wolber, Robert\|Bryan, Jennifer\|Hughesman, Curtis\|Haynes, Charles
PMID:	26762843

1378.
Journal:	Crit Rev Oncol Hematol. 2016 Mar;99:150-7.
Title:	Can KRAS and BRAF mutations limit the benefit of liver resection in metastatic colorectal cancer patients? A systematic review and meta-analysis.
Author:	Passiglia, Francesco\|Bronte, Giuseppe\|Bazan, Viviana\|Galvano, Antonio\|Vincenzi, Bruno\|Russo, Antonio
PMID:	26775732

1379.
Journal:	Endocr Pathol. 2016 Sep;27(3):220-3.
Title:	Critical Pitfalls in the use of BRAF Mutation as a Diagnostic Tool in Thyroid Nodules: a Case Report.
Author:	Kuhn, Elisabetta\|Ragazzi, Moira\|Zini, Michele\|Giordano, Davide\|Nicoli, Davide\|Piana, Simonetta
PMID:	26782803

1380.
Journal:	Proc Natl Acad Sci U S A. 2016 Feb 2;113(5):1250-5.
Title:	Common BRAF(V600E)-directed pathway mediates widespread epigenetic silencing in colorectal cancer and melanoma.
Author:	Fang, Minggang\|Hutchinson, Lloyd\|Deng, April\|Green, Michael R
PMID:	26787892

1381.
Journal:	Oncotarget. 2016 Feb 23;7(8):9188-221.
Title:	BRAF associated autophagy exploitation: BRAF and autophagy inhibitors synergise to efficiently overcome resistance of BRAF mutant colorectal cancer cells.
Author:	Goulielmaki, Maria\|Koustas, Evangelos\|Moysidou, Eirini\|Vlassi, Margarita\|Sasazuki, Takehiko\|Shirasawa, Senji\|Zografos, George\|Oikonomou, Eftychia\|Pintzas, Alexander
PMID:	26802026

1382.
Journal:	Cancer Biol Ther. 2016;17(2):199-207.
Title:	EBI-907, a novel BRAF(V600E) inhibitor, has potent oral anti-tumor activity and a broad kinase selectivity profile.
Author:	Zhang, Jiayin\|Lu, Biao\|Liu, Dong\|Shen, Ru\|Yan, Yinfa\|Yang, Liuqing\|Zhang, Minsheng\|Zhang, Lei\|Cao, Guoqing\|Cao, Hu\|Fu, Beibei\|Gong, Aishen\|Sun, Qiming\|Wan, Hong\|Zhang, Lianshan\|Tao, Weikang\|Cao, Jingsong
PMID:	26810733

1383.
Journal:	Dig Surg. 2016;33(2):157-63.
Title:	Right Sided Colon Cancer as a Distinct Histopathological Subtype with Reduced Prognosis.
Author:	Nitsche, Ulrich\|Stogbauer, Fabian\|Spath, Christoph\|Haller, Bernhard\|Wilhelm, Dirk\|Friess, Helmut\|Bader, Franz G
PMID:	26824772

1384.
Journal:	Tumour Biol. 2016 Aug;37(8):10209-18.
Title:	Clinical significance of fibroblast growth factor receptor 2 expression in patients with residual rectal cancer after preoperative chemoradiotherapy: relationship with KRAS or BRAF mutations and MSI status.
Author:	Yoon, Ghilsuk\|Lee, Hwayoung\|Kim, Jae-Hoon\|Hur, Keun\|Seo, An Na
PMID:	26831663

1385.
Journal:	Cell Oncol (Dordr). 2016 Jun;39(3):243-52.
Title:	Biomarkers for the identification of precursor polyps of colorectal serrated adenocarcinomas.
Author:	Garcia-Solano, Jose\|Garcia-Solano, Maria Eulalia\|Torres-Moreno, Daniel\|Carbonell, Pablo\|Trujillo-Santos, Javier\|Perez-Guillermo, Miguel\|Conesa-Zamora, Pablo
PMID:	26832730

1386.
Journal:	Curr Oncol Rep. 2016 Mar;18(3):18.
Title:	New Therapeutic Opportunities Based on DNA Mismatch Repair and BRAF Status in Metastatic Colorectal Cancer.
Author:	Cohen, Romain\|Svrcek, Magali\|Dreyer, Chantal\|Cervera, Pascale\|Duval, Alex\|Pocard, Marc\|Flejou, Jean-Francois\|de Gramont, Aimery\|Andre, Thierry
PMID:	26861657

1387.
Journal:	BMC Syst Biol. 2016 Feb 11;10:16.
Title:	Integrative modeling of multi-omics data to identify cancer drivers and infer patient-specific gene activity.
Author:	Pavel, Ana B\|Sonkin, Dmitriy\|Reddy, Anupama
PMID:	26864072

1388.
Journal:	Cancer Sci. 2016 May;107(5):601-8.
Title:	Multikinase inhibitor regorafenib inhibits the growth and metastasis of colon cancer with abundant stroma.
Author:	Takigawa, Hidehiko\|Kitadai, Yasuhiko\|Shinagawa, Kei\|Yuge, Ryo\|Higashi, Yukihito\|Tanaka, Shinji\|Yasui, Wataru\|Chayama, Kazuaki
PMID:	26865419

1389.
Journal:	Genet Med. 2016 Sep;18(9):863-8.
Title:	Patients with colorectal cancer associated with Lynch syndrome and MLH1 promoter hypermethylation have similar prognoses.
Author:	Haraldsdottir, Sigurdis\|Hampel, Heather\|Wu, Christina\|Weng, Daniel Y\|Shields, Peter G\|Frankel, Wendy L\|Pan, Xueliang\|de la Chapelle, Albert\|Goldberg, Richard M\|Bekaii-Saab, Tanios
PMID:	26866578

1390.
Journal:	JAMA Oncol. 2016 Feb 11. pii: 2490542.
Title:	Combined Epiregulin and Amphiregulin Expression Levels as a Predictive Biomarker for Panitumumab Therapy Benefit or Lack of Benefit in Patients With RAS Wild-Type Advanced Colorectal Cancer.
Author:	Seligmann, Jenny F\|Elliott, Faye\|Richman, Susan D\|Jacobs, Bart\|Hemmings, Gemma\|Brown, Sarah\|Barrett, Jennifer H\|Tejpar, Sabine\|Quirke, Philip\|Seymour, Matthew T
PMID:	26867820

1391.
Journal:	Onco Targets Ther. 2016 Jan 27;9:557-65.
Title:	Biomarkers predicting resistance to epidermal growth factor receptor-targeted therapy in metastatic colorectal cancer with wild-type KRAS.
Author:	Liu, Jiang\|Hu, Jing\|Cheng, Lei\|Ren, Wei\|Yang, Mi\|Liu, Baorui\|Xie, Li\|Qian, Xiaoping
PMID:	26869800

1392.
Journal:	Oncol Lett. 2016 Jan;11(1):731-734.
Title:	Expression of hepatocyte growth factor and c-Met is characteristic of alpha-fetoprotein-producing colorectal adenocarcinoma: A report of three cases.
Author:	Li, Jun\|Liu, Yue\|Xu, Jing-Hong\|Xu, Zheng-Ping\|Zheng, Shu\|Ding, Ke-Feng
PMID:	26870275

1393.
Journal:	Oncotarget. 2016 Mar 15;7(11):12704-17.
Title:	The relationship between EZH2 expression and microRNA-31 in colorectal cancer and the role in evolution of the serrated pathway.
Author:	Kurihara, Hiroyoshi\|Maruyama, Reo\|Ishiguro, Kazuya\|Kanno, Shinichi\|Yamamoto, Itaru\|Ishigami, Keisuke\|Mitsuhashi, Kei\|Igarashi, Hisayoshi\|Ito, Miki\|Tanuma, Tokuma\|Sukawa, Yasutaka\|Okita, Kenji\|Hasegawa, Tadashi\|Imai, Kohzoh\|Yamamoto, Hiroyuki\|Shinomura, Ya
PMID:	26871294

1394.
Journal:	Clin Gastroenterol Hepatol. 2016 May;14(5):651-8.
Title:	Molecular Biomarkers in the Personalized Treatment of Colorectal Cancer.
Author:	Sinicrope, Frank A\|Okamoto, Koichi\|Kasi, Pashtoon M\|Kawakami, Hisato
PMID:	26872400

1395.
Journal:	Oncotarget. 2016 Mar 22;7(12):14095-111.
Title:	Distinct features between MLH1-methylated and unmethylated colorectal carcinomas with the CpG island methylator phenotype: implications in the serrated neoplasia pathway.
Author:	Kim, Jung Ho\|Bae, Jeong Mo\|Cho, Nam-Yun\|Kang, Gyeong Hoon
PMID:	26883113

1396.
Journal:	BMC Cancer. 2016 Feb 18;16:120.
Title:	The impact of KRAS mutations on prognosis in surgically resected colorectal cancer patients with liver and lung metastases: a retrospective analysis.
Author:	Kim, Hae Su\|Heo, Jin Seok\|Lee, Jeeyun\|Lee, Ji Yun\|Lee, Min-Young\|Lim, Sung Hee\|Lee, Woo Yong\|Kim, Seok Hyung\|Park, Yoon Ah\|Cho, Yong Beom\|Yun, Seong Hyeon\|Kim, Seung Tae\|Park, Joon Oh\|Lim, Ho Yeong\|Choi, Yong Soo\|Kwon, Woo Il\|Kim, Hee Cheol\|Park, Young Su
PMID:	26887348

1397.
Journal:	Mod Pathol. 2016 Apr;29(4):402-15.
Title:	Clinicopathologic and prognostic associations of KRAS and BRAF mutations in small intestinal adenocarcinoma.
Author:	Jun, Sun-Young\|Kim, Misung\|Jin Gu, Mi\|Kyung Bae, Young\|Chang, Hee-Kyung\|Sun Jung, Eun\|Jang, Kee-Taek\|Kim, Jihun\|Yu, Eunsil\|Woon Eom, Dae\|Hong, Seung-Mo
PMID:	26892442

1398.
Journal:	Oncol Lett. 2016 Feb;11(2):1223-1229.
Title:	Association between the expression levels of TAZ, AXL and CTGF and clinicopathological parameters in patients with colon cancer.
Author:	Zhang, Shu-Dong\|McCrudden, Cian M\|Yuen, Hiu-Fung\|Leung, Ka Lai\|Hong, Wan-Jin\|Kwok, Hang Fai
PMID:	26893723

1399.
Journal:	Clin Gastroenterol Hepatol. 2016 Jul;14(7):1056-9.
Title:	Sessile Serrated Polyps are Precursors of Colon Carcinomas With Deficient DNA Mismatch Repair.
Author:	Sweetser, Seth\|Jones, Andrea\|Smyrk, Thomas C\|Sinicrope, Frank A
PMID:	26898652

1400.
Journal:	Oncotarget. 2016 Apr 12;7(15):19610-9.
Title:	Molecular characterization of colorectal cancer patients and concomitant patient-derived tumor cell establishment.
Author:	Song, Haa-Na\|Lee, Chung\|Kim, Seung Tae\|Kim, Sun Young\|Kim, Nayoung K D\|Jang, Jiryeon\|Kang, Mihyun\|Jang, Hyojin\|Ahn, Soomin\|Kim, Seok Hyeong\|Park, Yoona\|Cho, Yong Beom\|Heo, Jeong Wook\|Lee, Woo Yong\|Park, Joon Oh\|Lim, Ho Yeong\|Kang, Won Ki\|Park, Young Suk\|P
PMID:	26909603

1401.
Journal:	Oncotarget. 2016 Mar 29;7(13):17265-74.
Title:	Clinicopathologic distribution of KRAS and BRAF mutations in a Chinese population with colorectal cancer precursor lesions.
Author:	Yi, Chenghao\|Huang, Yanqing\|Yu, Xing\|Li, Xiaofen\|Zheng, Shu\|Ding, Kefeng\|Xu, Jinghong
PMID:	26910894

1402.
Journal:	Mol Cancer Ther. 2016 Mar;15(3):354-65.
Title:	A Novel RAF Kinase Inhibitor with DFG-Out-Binding Mode: High Efficacy in BRAF-Mutant Tumor Xenograft Models in the Absence of Normal Tissue Hyperproliferation.
Author:	Waizenegger, Irene C\|Baum, Anke\|Steurer, Steffen\|Stadtmuller, Heinz\|Bader, Gerd\|Schaaf, Otmar\|Garin-Chesa, Pilar\|Schlattl, Andreas\|Schweifer, Norbert\|Haslinger, Christian\|Colbatzky, Florian\|Mousa, Sien\|Kalkuhl, Arno\|Kraut, Norbert\|Adolf, Gunther R
PMID:	26916115

1403.
Journal:	Genes Chromosomes Cancer. 2016 Jun;55(6):505-21.
Title:	Genotyping of colorectal cancer for cancer precision medicine: Results from the IPH Center for Molecular Pathology.
Author:	Jesinghaus, Moritz\|Pfarr, Nicole\|Endris, Volker\|Kloor, Matthias\|Volckmar, Anna-Lena\|Brandt, Regine\|Herpel, Esther\|Muckenhuber, Alexander\|Lasitschka, Felix\|Schirmacher, Peter\|Penzel, Roland\|Weichert, Wilko\|Stenzinger, Albrecht
PMID:	26917275

1404.
Journal:	Asian Pac J Cancer Prev. 2016;17(2):539-43.
Title:	Value of KRAS, BRAF, and PIK3CA Mutations and Survival Benefit from Systemic Chemotherapy in Colorectal Peritoneal Carcinomatosis.
Author:	Sasaki, Yusuke\|Hamaguchi, Tetsuya\|Yamada, Yasuhide\|Takahashi, Naoki\|Shoji, Hirokazu\|Honma, Yoshitaka\|Iwasa, Satoru\|Okita, Natsuko\|Takashima, Atsuo\|Kato, Ken\|Nagai, Yushi\|Taniguchi, Hirokazu\|Boku, Narikazu\|Ushijima, Toshikazu\|Shimada, Yasuhiro
PMID:	26925640

1405.
Journal:	Asian Pac J Cancer Prev. 2016;17(2):603-8.
Title:	Mutation Analysis of KRAS and BRAF Genes in Metastatic Colorectal Cancer: a First Large Scale Study from Iran.
Author:	Koochak, Aghigh\|Rakhshani, Nasser\|Karbalaie Niya, Mohammad Hadi\|Tameshkel, Fahimeh Safarnezhad\|Sohrabi, Masoud Reza\|Babaee, Mohammad Reza\|Rezvani, Hamid\|Bahar, Babak\|Imanzade, Farid\|Zamani, Farhad\|Khonsari, Mohammad Reza\|Ajdarkosh, Hossein\|Hemmasi, Gholam
PMID:	26925650

1406.
Journal:	Clin Cancer Res. 2016 Aug 1;22(15):3841-8.
Title:	MicroRNA MIR21 (miR-21) and PTGS2 Expression in Colorectal Cancer and Patient Survival.
Author:	Mima, Kosuke\|Nishihara, Reiko\|Yang, Juhong\|Dou, Ruoxu\|Masugi, Yohei\|Shi, Yan\|da Silva, Annacarolina\|Cao, Yin\|Song, Mingyang\|Nowak, Jonathan\|Gu, Mancang\|Li, Wanwan\|Morikawa, Teppei\|Zhang, Xuehong\|Wu, Kana\|Baba, Hideo\|Giovannucci, Edward L\|Meyerhardt, Jeffr
PMID:	26957558

1407.
Journal:	Cell Cycle. 2016;15(4):506-18.
Title:	Tumor cells with KRAS or BRAF mutations or ERK5/MAPK7 amplification are not addicted to ERK5 activity for cell proliferation.
Author:	Lochhead, Pamela A\|Clark, Jonathan\|Wang, Lan-Zhen\|Gilmour, Lesley\|Squires, Matthew\|Gilley, Rebecca\|Foxton, Caroline\|Newell, David R\|Wedge, Stephen R\|Cook, Simon J
PMID:	26959608

1408.
Journal:	J Oncol Pract. 2016 Mar;12(3):e308-19, 259-60.
Title:	Oncologists' Selection of Genetic and Molecular Testing in the Evolving Landscape of Stage II Colorectal Cancer.
Author:	Parikh, Aparna R\|Keating, Nancy L\|Liu, Pang-Hsiang\|Gray, Stacy W\|Klabunde, Carrie N\|Kahn, Katherine L\|Haggstrom, David A\|Syngal, Sapna\|Kim, Benjamin
PMID:	26962170

1409.
Journal:	Clin Transl Gastroenterol. 2016 Mar 10;7:e151.
Title:	Tracking the Correlation Between CpG Island Methylator Phenotype and Other Molecular Features and Clinicopathological Features in Human Colorectal Cancers: A Systematic Review and Meta-Analysis.
Author:	Zong, Liang\|Abe, Masanobu\|Ji, Jiafu\|Zhu, Wei-Guo\|Yu, Duonan
PMID:	26963001

1410.
Journal:	Mol Cancer Ther. 2016 Jun;15(6):1217-26.
Title:	Dual Targeting of Bromodomain and Extraterminal Domain Proteins, and WNT or MAPK Signaling, Inhibits c-MYC Expression and Proliferation of Colorectal Cancer Cells.
Author:	Togel, Lars\|Nightingale, Rebecca\|Chueh, Anderly C\|Jayachandran, Aparna\|Tran, Hoanh\|Phesse, Toby\|Wu, Rui\|Sieber, Oliver M\|Arango, Diego\|Dhillon, Amardeep S\|Dawson, Mark A\|Diez-Dacal, Beatriz\|Gahman, Timothy C\|Filippakopoulos, Panagis\|Shiau, Andrew K\|Mariad
PMID:	26983878

1411.
Journal:	PLoS One. 2016 Mar 18;11(3):e0151865.
Title:	BRAF, PIK3CA, and HER2 Oncogenic Alterations According to KRAS Mutation Status in Advanced Colorectal Cancers with Distant Metastasis.
Author:	Nam, Soo Kyung\|Yun, Sumi\|Koh, Jiwon\|Kwak, Yoonjin\|Seo, An Na\|Park, Kyoung Un\|Kim, Duck-Woo\|Kang, Sung-Bum\|Kim, Woo Ho\|Lee, Hye Seung
PMID:	26991109

1412.
Journal:	Int J Cancer. 2016 Aug 1;139(3):647-56.
Title:	Impact of KRAS, BRAF, PIK3CA, TP53 status and intraindividual mutation heterogeneity on outcome after liver resection for colorectal cancer metastases.
Author:	Loes, Inger Marie\|Immervoll, Heike\|Sorbye, Halfdan\|Angelsen, Jon-Helge\|Horn, Arild\|Knappskog, Stian\|Lonning, Per Eystein
PMID:	26991344

1413.
Journal:	Hum Pathol. 2016 Jul;53:91-6.
Title:	Medullary carcinoma in the colorectum: a systematic review and meta-analysis.
Author:	Pyo, Jung-Soo\|Sohn, Jin Hee\|Kang, Guhyun
PMID:	27001432

1414.
Journal:	Ann Oncol. 2016 Jun;27(6):1055-61.
Title:	Cetuximab continuation after first progression in metastatic colorectal cancer (CAPRI-GOIM): a randomized phase II trial of FOLFOX plus cetuximab versus FOLFOX.
Author:	Ciardiello, F\|Normanno, N\|Martinelli, E\|Troiani, T\|Pisconti, S\|Cardone, C\|Nappi, A\|Bordonaro, A R\|Rachiglio, M\|Lambiase, M\|Latiano, T P\|Modoni, G\|Cordio, S\|Giuliani, F\|Biglietto, M\|Montesarchio, V\|Barone, C\|Tonini, G\|Cinieri, S\|Febbraro, A\|Rizzi, D\|De Vit
PMID:	27002107

1415.
Journal:	Cancer Treat Rev. 2016 Apr;45:97-104.
Title:	Reconsidering the benefit of intermittent versus continuous treatment in the maintenance treatment setting of metastatic colorectal cancer.
Author:	Sunakawa, Y\|Bekaii-Saab, T\|Stintzing, S
PMID:	27002945

1416.
Journal:	Int J Cancer. 2016 Aug 15;139(4):803-11.
Title:	RAS mutation is a prognostic biomarker in colorectal cancer patients with metastasectomy.
Author:	Osumi, Hiroki\|Shinozaki, Eiji\|Suenaga, Mitsukuni\|Matsusaka, Satoshi\|Konishi, Tsuyoshi\|Akiyoshi, Takashi\|Fujimoto, Yoshiya\|Nagayama, Satoshi\|Fukunaga, Yosuke\|Ueno, Masashi\|Mise, Yoshihiro\|Ishizawa, Takeaki\|Inoue, Yosuke\|Takahashi, Yu\|Saiura, Akio\|Uehara, H
PMID:	27004837

1417.
Journal:	Mol Cancer Ther. 2016 Apr;15(4):533-47.
Title:	Genomically Driven Tumors and Actionability across Histologies: BRAF-Mutant Cancers as a Paradigm.
Author:	Turski, Michelle L\|Vidwans, Smruti J\|Janku, Filip\|Garrido-Laguna, Ignacio\|Munoz, Javier\|Schwab, Richard\|Subbiah, Vivek\|Rodon, Jordi\|Kurzrock, Razelle
PMID:	27009213

1418.
Journal:	Expert Rev Anticancer Ther. 2016 May;16(5):557-71.
Title:	Update on optimal treatment for metastatic colorectal cancer from the ACTG/AGITG expert meeting: ECCO 2015.
Author:	Price, Timothy J\|Thavaneswaran, Subotheni\|Burge, Matthew\|Segelov, Eva\|Haller, Daniel G\|Punt, Cornelis Ja\|Arnold, Dirk\|Karapetis, Christos S\|Tebbutt, Niall C\|Pavlakis, Nick\|Gibbs, Peter\|Shapiro, Jeremy D
PMID:	27010906

1419.
Journal:	Crit Rev Oncol Hematol. 2016 May;101:151-7.
Title:	Dual targeting of HER3 and EGFR in colorectal tumors might overcome anti-EGFR resistance.
Author:	Temraz, Sally\|Mukherji, Deborah\|Shamseddine, Ali
PMID:	27017409

1420.
Journal:	J Clin Oncol. 2016 Jun 20;34(18):2141-7.
Title:	Reliable Detection of Mismatch Repair Deficiency in Colorectal Cancers Using Mutational Load in Next-Generation Sequencing Panels.
Author:	Stadler, Zsofia K\|Battaglin, Francesca\|Middha, Sumit\|Hechtman, Jaclyn F\|Tran, Christina\|Cercek, Andrea\|Yaeger, Rona\|Segal, Neil H\|Varghese, Anna M\|Reidy-Lagunes, Diane L\|Kemeny, Nancy E\|Salo-Mullen, Erin E\|Ashraf, Asad\|Weiser, Martin R\|Garcia-Aguilar, Jul
PMID:	27022117

1421.
Journal:	Int J Colorectal Dis. 2016 May;31(5):973-982.
Title:	Colorectal cancer in Crohn's colitis is comparable to sporadic colorectal cancer.
Author:	Lennerz, Jochen K\|van der Sloot, Kimberley W J\|Le, Long Phi\|Batten, Julie M\|Han, Jae Young\|Fan, Kenneth C\|Siegel, Corey A\|Srivastava, Amitabh\|Park, Do Youn\|Chen, Jey-Hsin\|Sands, Bruce E\|Korzenik, Joshua R\|Odze, Robert D\|Dias-Santagata, Dora\|Borger, Darrel
PMID:	27026089

1422.
Journal:	Cancer Prev Res (Phila). 2016 Jun;9(6):456-65.
Title:	Gene Signature in Sessile Serrated Polyps Identifies Colon Cancer Subtype.
Author:	Kanth, Priyanka\|Bronner, Mary P\|Boucher, Kenneth M\|Burt, Randall W\|Neklason, Deborah W\|Hagedorn, Curt H\|Delker, Don A
PMID:	27026680

1423.
Journal:	Pathol Oncol Res. 2016 Oct;22(4):707-14.
Title:	The Prognostic Influence of BRAF Mutation and other Molecular, Clinical and Laboratory Parameters in Stage IV Colorectal Cancer.
Author:	Karadima, Maria L\|Saetta, Angelica A\|Chatziandreou, Ilenia\|Lazaris, Andreas C\|Patsouris, Efstratios\|Tsavaris, Nikolaos
PMID:	27033063

1424.
Journal:	Med Oncol. 2016 May;33(5):39.
Title:	BRAF mutation may have different prognostic implications in early- and late-stage colorectal cancer.
Author:	Chen, Kuo-Hsing\|Lin, Yu-Lin\|Liau, Jau-Yu\|Tsai, Jia-Huei\|Tseng, Li-Hui\|Lin, Liang-In\|Liang, Jin-Tung\|Lin, Been-Ren\|Hung, Ji-Shiang\|Chang, Yih-Leong\|Yeh, Kun-Huei\|Cheng, Ann-Lii
PMID:	27034263

1425.
Journal:	J Gastrointest Oncol. 2016 Apr;7(Suppl 1):S11-20.
Title:	Molecular testing to optimize therapeutic decision making in advanced colorectal cancer.
Author:	Semrad, Thomas J\|Kim, Edward J
PMID:	27034809

1426.
Journal:	Hum Pathol. 2016 Aug;54:37-46.
Title:	Localization of active, dually phosphorylated extracellular signal-regulated kinase 1 and 2 in colorectal cancer with or without activating BRAF and KRAS mutations.
Author:	Holck, Susanne\|Bonde, Jesper\|Pedersen, Helle\|Petersen, Anja Alex\|Chaube, Amita\|Nielsen, Hans Jorgen\|Larsson, Lars-Inge
PMID:	27036313

1427.
Journal:	BMC Cancer. 2016 Apr 1;16:260.
Title:	Systematic review: brain metastases from colorectal cancer--Incidence and patient characteristics.
Author:	Christensen, Troels Dreier\|Spindler, Karen-Lise Garm\|Palshof, Jesper Andreas\|Nielsen, Dorte Lisbet
PMID:	27037031

1428.
Journal:	Asian Pac J Cancer Prev. 2016;17(3):1175-9.
Title:	Distribution of KRAS and BRAF Mutations in Metastatic Colorectal Cancers in Turkish Patients.
Author:	Gorukmez, Orhan\|Yakut, Tahsin\|Gorukmez, Ozlem\|Sag, Sebnem Ozemri\|Karkucak, Mutlu\|Kanat, Ozkan
PMID:	27039744

1429.
Journal:	Cancer Discov. 2016 Jun;6(6):594-600.
Title:	BRAFV600E Mutations in High-Grade Colorectal Neuroendocrine Tumors May Predict Responsiveness to BRAF-MEK Combination Therapy.
Author:	Klempner, Samuel J\|Gershenhorn, Bruce\|Tran, Phu\|Lee, Thomas K\|Erlander, Mark G\|Gowen, Kyle\|Schrock, Alexa B\|Morosini, Deborah\|Ross, Jeffrey S\|Miller, Vincent A\|Stephens, Philip J\|Ou, Sai-Hong Ignatius\|Ali, Siraj M
PMID:	27048246

1430.
Journal:	World J Gastroenterol. 2016 Apr 7;22(13):3516-30.
Title:	Serrated colorectal cancer: Molecular classification, prognosis, and response to chemotherapy.
Author:	Murcia, Oscar\|Juarez, Miriam\|Hernandez-Illan, Eva\|Egoavil, Cecilia\|Giner-Calabuig, Mar\|Rodriguez-Soler, Maria\|Jover, Rodrigo
PMID:	27053844

1431.
Journal:	Cell. 2016 Apr 7;165(2):317-30.
Title:	A Vulnerability of a Subset of Colon Cancers with Potential Clinical Utility.
Author:	Vecchione, Loredana\|Gambino, Valentina\|Raaijmakers, Jonne\|Schlicker, Andreas\|Fumagalli, Arianna\|Russo, Mariangela\|Villanueva, Alberto\|Beerling, Evelyne\|Bartolini, Alice\|Mollevi, David G\|El-Murr, Nizar\|Chiron, Marielle\|Calvet, Loreley\|Nicolazzi, Celine\|Com
PMID:	27058664

1432.
Journal:	Gan To Kagaku Ryoho. 2016 Mar;43(3):294-9.
Title:	[Pathological Diagnosis and Its Molecular Basis in Colorectal Cancer].
Author:	Sugai, Tamotsu\|Habano, Wataru
PMID:	27067845

1433.
Journal:	Sci Rep. 2016 Apr 14;6:24310.
Title:	Prognostic impact of mutation profiling in patients with stage II and III colon cancer.
Author:	Shen, Yinchen\|Han, Xiaohong\|Wang, Jianfei\|Wang, Shuai\|Yang, Hongying\|Lu, Shih-Hsin\|Shi, Yuankai
PMID:	27074743

1434.
Journal:	Medicine (Baltimore). 2016 Apr;95(15):e3321.
Title:	MicroRNA Expression Signatures Associated With BRAF-Mutated Versus KRAS-Mutated Colorectal Cancers.
Author:	Choi, Yong Won\|Song, Young Soo\|Lee, Hyunwoo\|Yi, Kijong\|Kim, Young-Bae\|Suh, Kwang Wook\|Lee, Dakeun
PMID:	27082577

1435.
Journal:	United European Gastroenterol J. 2016 Apr;4(2):288-96.
Title:	Sporadic colorectal cancer: Studying ways to an end.
Author:	Rosa, Isadora\|Fidalgo, Paulo\|Filipe, Bruno\|Albuquerque, Cristina\|Fonseca, Ricardo\|Chaves, Paula\|Pereira, Antonio D
PMID:	27087959

1436.
Journal:	Gastroenterol Hepatol Bed Bench. 2016 Spring;9(2):94-9.
Title:	Lack of BRAFV600E mutation in stage I and II of colorectal cancer.
Author:	Molaei, Mahsa\|Kishani Farahani, Roya\|Maftouh, Mina\|Taleghani, Mohammad Yaghoob\|Vahdatinia, Mahsa\|Khatami, Fatemeh\|Nazemalhosseini-Mojarad, Ehsan\|Asadzadeh Aghdae, Hamid\|Aboutorabi, Akram\|Zali, Mohammad Reza
PMID:	27099668

1437.
Journal:	PLoS One. 2016 Apr 21;11(4):e0154038.
Title:	Validation and Application of a Custom-Designed Targeted Next-Generation Sequencing Panel for the Diagnostic Mutational Profiling of Solid Tumors.
Author:	Froyen, Guy\|Broekmans, An\|Hillen, Femke\|Pat, Karin\|Achten, Ruth\|Mebis, Jeroen\|Rummens, Jean-Luc\|Willemse, Johan\|Maes, Brigitte
PMID:	27101000

1438.
Journal:	Cancer Discov. 2016 Jun;6(6):OF18.
Title:	BRAF-Like Colorectal Cancer Cells Are Selectively Dependent on RANBP2.
Author:
PMID:	27102074

1439.
Journal:	Clin Colorectal Cancer. 2016 Dec;15(4):e235-e239.
Title:	Neuroendocrine Differentiation of a Primary BRAF Mutant Colon Cancer in a Patient With a History of Hairy Cell Leukemia.
Author:	Shah, Harsh\|McPherson, Katie\|Mansour, Ahmad\|Ramirez-Santrich, Cecilia\|Nassiri, Mehdi\|Shahda, Safi
PMID:	27117521

1440.
Journal:	PLoS One. 2016 Apr 28;11(4):e0154326.
Title:	Biobanking of Fresh-Frozen Human Adenocarcinomatous and Normal Colon Tissues: Which Parameters Influence RNA Quality?
Author:	Galissier, Thibaut\|Schneider, Christophe\|Nasri, Saviz\|Kanagaratnam, Lukshe\|Fichel, Caroline\|Coquelet, Christelle\|Diebold, Marie-Daniele\|Kianmanesh, Reza\|Bellon, Georges\|Dedieu, Stephane\|Marchal Bressenot, Aude\|Boulagnon-Rombi, Camille
PMID:	27124490

1441.
Journal:	Bosn J Basic Med Sci. 2016 Nov 10;16(4):254-260.
Title:	Microsatellite instability and B-type Raf proto-oncogene mutation in colorectal cancer: Clinicopathological characteristics and effects on survival.
Author:	Batur, Sebnem\|Vuralli Bakkaloglu, Dogu\|Kepil, Nuray\|Erdamar, Sibel
PMID:	27131021

1442.
Journal:	PLoS One. 2016 May 3;11(5):e0154795.
Title:	Prognostic Role of BRAF Mutation in Stage II/III Colorectal Cancer Receiving Curative Resection and Adjuvant Chemotherapy: A Meta-Analysis Based on Randomized Clinical Trials.
Author:	Zhu, Lizhen\|Dong, Caixia\|Cao, Ying\|Fang, Xuefeng\|Zhong, Chenhan\|Li, Dan\|Yuan, Ying
PMID:	27138801

1443.
Journal:	Br J Radiol. 2016 Jul;89(1063):20160212.
Title:	(18)F-FDG PET/CT imaging in rectal cancer: relationship with the RAS mutational status.
Author:	Lovinfosse, Pierre\|Koopmansch, Benjamin\|Lambert, Frederic\|Jodogne, Sebastien\|Kustermans, Gaelle\|Hatt, Mathieu\|Visvikis, Dimitris\|Seidel, Laurence\|Polus, Marc\|Albert, Adelin\|Delvenne, Philippe\|Hustinx, Roland
PMID:	27146067

1444.
Journal:	Swiss Med Wkly. 2016 May 6;146:w14315.
Title:	Systematic immunohistochemical screening for Lynch syndrome in colorectal cancer: a single centre experience of 486 patients.
Author:	Zumstein, Valentin\|Vinzens, Fabrizio\|Zettl, Andreas\|Heinimann, Karl\|Koeberle, Dieter\|von Flue, Markus\|Bolli, Martin
PMID:	27152634

1445.
Journal:	Ann Oncol. 2016 Aug;27(8):1456-66.
Title:	Challenging chemoresistant metastatic colorectal cancer: therapeutic strategies from the clinic and from the laboratory.
Author:	Sartore-Bianchi, A\|Loupakis, F\|Argiles, G\|Prager, G W
PMID:	27154421

1446.
Journal:	J Mol Diagn. 2016 Jul;18(4):471-9.
Title:	Driver Gene Mutations in Stools of Colorectal Carcinoma Patients Detected by Targeted Next-Generation Sequencing.
Author:	Armengol, Gemma\|Sarhadi, Virinder K\|Ghanbari, Reza\|Doghaei-Moghaddam, Masoud\|Ansari, Reza\|Sotoudeh, Masoud\|Puolakkainen, Pauli\|Kokkola, Arto\|Malekzadeh, Reza\|Knuutila, Sakari
PMID:	27155048

1447.
Journal:	J Transl Med. 2016 May 10;14(1):128.
Title:	Significant association and synergistic adverse prognostic effect of podocalyxin-like protein and epidermal growth factor receptor expression in colorectal cancer.
Author:	Larsson, Anna H\|Lehn, Sophie\|Wangefjord, Sakarias\|Karnevi, Emelie\|Kuteeva, Eugenia\|Sundstrom, Magnus\|Nodin, Bjorn\|Uhlen, Mathias\|Eberhard, Jakob\|Birgisson, Helgi\|Jirstrom, Karin
PMID:	27160084

1448.
Journal:	Oncotarget. 2016 Jun 14;7(24):36474-36488.
Title:	Relative telomere lengths in tumor and normal mucosa are related to disease progression and chromosome instability profiles in colorectal cancer.
Author:	Suraweera, Nirosha\|Mouradov, Dmitri\|Li, Shan\|Jorissen, Robert N\|Hampson, Debbie\|Ghosh, Anil\|Sengupta, Neel\|Thaha, Mohamed\|Ahmed, Shafi\|Kirwan, Michael\|Aleva, Floor\|Propper, David\|Feakins, Roger M\|Vulliamy, Tom\|Elwood, Ngaire J\|Tian, Pei\|Ward, Robyn L\|Hawk
PMID:	27167335

1449.
Journal:	Zhonghua Zhong Liu Za Zhi. 2016 May 23;38(5):397-400.
Title:	[Insights on colorectal carcinoma based on the biological differences between left-sided and right- sided colon cancers].
Author:	Xu, J M
PMID:	27188617

1450.
Journal:	Br J Cancer. 2016 Jun 14;114(12):1334-42.
Title:	Clinical impact and network of determinants of tumour necrosis in colorectal cancer.
Author:	Vayrynen, Sara A\|Vayrynen, Juha P\|Klintrup, Kai\|Makela, Jyrki\|Karttunen, Tuomo J\|Tuomisto, Anne\|Makinen, Markus J
PMID:	27195424

1451.
Journal:	Pathol Oncol Res. 2016 Oct;22(4):831-7.
Title:	Diagnostic Accuracy of BRAF Immunohistochemistry in Colorectal Cancer: a Meta-Analysis and Diagnostic Test Accuracy Review.
Author:	Pyo, Jung-Soo\|Sohn, Jin Hee\|Kang, Guhyun
PMID:	27197524

1452.
Journal:	Mod Pathol. 2016 Sep;29(9):1104-12.
Title:	PD-L1 expression in colorectal cancer is associated with microsatellite instability, BRAF mutation, medullary morphology and cytotoxic tumor-infiltrating lymphocytes.
Author:	Rosenbaum, Matthew W\|Bledsoe, Jacob R\|Morales-Oyarvide, Vicente\|Huynh, Tiffany G\|Mino-Kenudson, Mari
PMID:	27198569

1453.
Journal:	Mod Pathol. 2016 Aug;29(8):915-27.
Title:	Colorectal tumor molecular phenotype and miRNA: expression profiles and prognosis.
Author:	Slattery, Martha L\|Herrick, Jennifer S\|Mullany, Lila E\|Wolff, Erica\|Hoffman, Michael D\|Pellatt, Daniel F\|Stevens, John R\|Wolff, Roger K
PMID:	27198570

1454.
Journal:	Cell Chem Biol. 2016 May 19;23(5):537-539.
Title:	Linking Nucleoporins, Mitosis, and Colon Cancer.
Author:	Wong, Richard W\|D'Angelo, Maximiliano
PMID:	27203373

1455.
Journal:	Zhonghua Wei Chang Wai Ke Za Zhi. 2016 May;19(5):495-8.
Title:	[Clinicopathological characteristics of colorectal carcinoma in the elderly].
Author:	Tao, Kaixiong\|Gao, Jinbo\|Wang, Guobin
PMID:	27215512

1456.
Journal:	Genes Chromosomes Cancer. 2016 Nov;55(11):821-33.
Title:	Copy number changes of clinically actionable genes in melanoma, non-small cell lung cancer and colorectal cancer-A survey across 822 routine diagnostic cases.
Author:	Pfarr, Nicole\|Penzel, Roland\|Klauschen, Frederick\|Heim, Daniel\|Brandt, Regine\|Kazdal, Daniel\|Jesinghaus, Moritz\|Herpel, Esther\|Schirmacher, Peter\|Warth, Arne\|Weichert, Wilko\|Endris, Volker\|Stenzinger, Albrecht
PMID:	27218826

1457.
Journal:	Virchows Arch. 2016 Aug;469(2):135-44.
Title:	Immunohistochemical staining for p16 and BRAFV600E is useful to distinguish between sporadic and hereditary (Lynch syndrome-related) microsatellite instable colorectal carcinomas.
Author:	Boissiere-Michot, Florence\|Frugier, Helene\|Ho-Pun-Cheung, Alexandre\|Lopez-Crapez, Evelyne\|Duffour, Jacqueline\|Bibeau, Frederic
PMID:	27220764

1458.
Journal:	EMBO Mol Med. 2016 Jul 1;8(7):745-60.
Title:	TGFbeta signaling directs serrated adenomas to the mesenchymal colorectal cancer subtype.
Author:	Fessler, Evelyn\|Drost, Jarno\|van Hooff, Sander R\|Linnekamp, Janneke F\|Wang, Xin\|Jansen, Marnix\|De Sousa E Melo, Felipe\|Prasetyanti, Pramudita R\|IJspeert, Joep Eg\|Franitza, Marek\|Nurnberg, Peter\|van Noesel, Carel Jm\|Dekker, Evelien\|Vermeulen, Louis\|Clevers
PMID:	27221051

1459.
Journal:	Asian Pac J Cancer Prev. 2016;17(4):1917-23.
Title:	Screening for Lynch Syndrome in Young Colorectal Cancer Patients from Saudi Arabia Using Microsatellite Instability as the Initial Test.
Author:	Alqahtani, Masood\|Grieu, Fabienne\|Carrello, Amerigo\|Amanuel, Benhur\|Mashour, Miral\|Alattas, Rabab\|Alsaleh, Khalid\|Alsheikh, Abdulmalik\|Alqahtani, Sarah\|Iacopetta, Barry
PMID:	27221876

1460.
Journal:	World J Gastroenterol. 2016 May 28;22(20):4936-45.
Title:	Longitudinal molecular characterization of endoscopic specimens from colorectal lesions.
Author:	Minarikova, Petra\|Benesova, Lucie\|Halkova, Tereza\|Belsanova, Barbora\|Suchanek, Stepan\|Cyrany, Jiri\|Tuckova, Inna\|Bures, Jan\|Zavoral, Miroslav\|Minarik, Marek
PMID:	27239120

1461.
Journal:	Cancer. 2016 Sep 15;122(18):2828-35.
Title:	Increased incidence of FBXW7 and POLE proofreading domain mutations in young adult colorectal cancers.
Author:	Kothari, Nishi\|Teer, Jamie K\|Abbott, Andrea M\|Srikumar, Thejal\|Zhang, Yonghong\|Yoder, Sean J\|Brohl, Andrew S\|Kim, Richard D\|Reed, Damon R\|Shibata, David
PMID:	27244218

1462.
Journal:	BMC Cancer. 2016 May 31;16:339.
Title:	ICECREAM: randomised phase II study of cetuximab alone or in combination with irinotecan in patients with metastatic colorectal cancer with either KRAS, NRAS, BRAF and PI3KCA wild type, or G13D mutated tumours.
Author:	Segelov, Eva\|Waring, Paul\|Desai, Jayesh\|Wilson, Kate\|Gebski, Val\|Thavaneswaran, Subotheni\|Elez, Elena\|Underhill, Craig\|Pavlakis, Nick\|Chantrill, Lorraine\|Nott, Louise\|Jefford, Michael\|Khasraw, Mustafa\|Day, Fiona\|Wasan, Harpreet\|Ciardiello, Fortunato\|Karap
PMID:	27246726

1463.
Journal:	Oncotarget. 2016 Aug 9;7(32):50875-50882.
Title:	Recurrent, truncating SOX9 mutations are associated with SOX9 overexpression, KRAS mutation, and TP53 wild type status in colorectal carcinoma.
Author:	Javier, Breanna M\|Yaeger, Rona\|Wang, Lu\|Sanchez-Vega, Francisco\|Zehir, Ahmet\|Middha, Sumit\|Sadowska, Justyna\|Vakiani, Efsevia\|Shia, Jinru\|Klimstra, David\|Ladanyi, Marc\|Iacobuzio-Donahue, Christine A\|Hechtman, Jaclyn F
PMID:	27248473

1464.
Journal:	Cancer Biol Ther. 2016 Aug 2;17(8):840-8.
Title:	BRAF V600E mutation in metastatic colorectal cancer: Methods of detection and correlation with clinical and pathologic features.
Author:	Roma, Cristin\|Rachiglio, Anna Maria\|Pasquale, Raffaella\|Fenizia, Francesca\|Iannaccone, Alessia\|Tatangelo, Fabiana\|Antinolfi, Giuseppe\|Parrella, Paola\|Graziano, Paolo\|Sabatino, Lina\|Colantuoni, Vittorio\|Botti, Gerardo\|Maiello, Evaristo\|Normanno, Nicola
PMID:	27261210

1465.
Journal:	Mol Med. 2016 Sep;22:271-273.
Title:	The prognostic yield of biomarkers harvested in chemotherapy-naive stage II colon cancer: can we separate the wheat from the chaff?
Author:	Watson, Martin M\|Soreide, Kjetil
PMID:	27262159

1466.
Journal:	Med Oncol. 2016 Jul;33(7):71.
Title:	Comparison of KRAS mutation status between primary tumor and metastasis in Chinese colorectal cancer patients.
Author:	Li, Zhe-Zhen\|Bai, Long\|Wang, Feng\|Zhang, Zi-Chen\|Wang, Fang\|Zeng, Zhao-Lei\|Zeng, Jun-Bo\|Zhang, Dong-Sheng\|Wang, Feng-Hua\|Wang, Zhi-Qiang\|Li, Yu-Hong\|Shao, Jian-Yong\|Xu, Rui-Hua
PMID:	27270901

1467.
Journal:	Br J Cancer. 2016 Jun 14;114(12):1352-61.
Title:	Association of CpG island methylator phenotype and EREG/AREG methylation and expression in colorectal cancer.
Author:	Lee, Michael S\|McGuffey, Elizabeth J\|Morris, Jeffrey S\|Manyam, Ganiraju\|Baladandayuthapani, Veerabahdran\|Wei, Wei\|Morris, Van K\|Overman, Michael J\|Maru, Dipen M\|Jiang, Zhi-Qin\|Hamilton, Stanley R\|Kopetz, Scott
PMID:	27272216

1468.
Journal:	Oncotarget. 2016 Jun 28;7(26):39293-39301.
Title:	Mutations of KRAS, NRAS, BRAF, EGFR, and PIK3CA genes in urachal carcinoma: Occurence and prognostic significance.
Author:	Modos, Orsolya\|Reis, Henning\|Niedworok, Christian\|Rubben, Herbert\|Szendroi, Attila\|Szasz, Marcell A\|Timar, Jozsef\|Baghy, Kornelia\|Kovalszky, Ilona\|Golabek, Tomasz\|Chlosta, Piotr\|Okon, Krzysztof\|Peyronnet, Benoit\|Mathieu, Romain\|Shariat, Shahrokh F\|Hollosi
PMID:	27283768

1469.
Journal:	Mol Clin Oncol. 2016 Jun;4(6):1017-1024.
Title:	Efficacy of cetuximab-based chemotherapy in metastatic colorectal cancer according to RAS and BRAF mutation subgroups: A meta-analysis.
Author:	Lin, L I\|Chen, Lu-Lu\|Wang, You\|Meng, Xiang-Yu\|Liang, Chen\|Zhou, Fu-Xiang
PMID:	27284437

1470.
Journal:	Klin Onkol. 2016;29(3):180-6.
Title:	[Lynch Syndrome - the Pathologist's Diagnosis].
Author:	Dusek, M\|Hadravsky, L\|Cerna, K\|Stehlik, J\|Svajdler, M\|Kokoskova, B\|Dubova, M\|Michal, M\|Daum, O
PMID:	27296402

1471.
Journal:	PLoS One. 2016 Jun 14;11(6):e0156659.
Title:	Clinicopathologic and Molecular Features of Colorectal Adenocarcinoma with Signet-Ring Cell Component.
Author:	Wei, Qing\|Wang, Xicheng\|Gao, Jing\|Li, Jian\|Li, Jie\|Qi, Changsong\|Li, Yanyan\|Li, Zhongwu\|Shen, Lin
PMID:	27300552

1472.
Journal:	Gastroenterology. 2016 Sep;151(3):440-447.e1.
Title:	Frequent PIK3CA Mutations in Colorectal and Endometrial Tumors With 2 or More Somatic Mutations in Mismatch Repair Genes.
Author:	Cohen, Stacey A\|Turner, Emily H\|Beightol, Mallory B\|Jacobson, Angela\|Gooley, Ted A\|Salipante, Stephen J\|Haraldsdottir, Sigurdis\|Smith, Christina\|Scroggins, Sheena\|Tait, Jonathan F\|Grady, William M\|Lin, Edward H\|Cohn, David E\|Goodfellow, Paul J\|Arnold, Mar
PMID:	27302833

1473.
Journal:	Am J Surg Pathol. 2016 Oct;40(10):1352-9.
Title:	RNF43 Is an Early and Specific Mutated Gene in the Serrated Pathway, With Increased Frequency in Traditional Serrated Adenoma and Its Associated Malignancy.
Author:	Tsai, Jia-Huei\|Liau, Jau-Yu\|Yuan, Chang-Tsu\|Lin, Yu-Lin\|Tseng, Li-Hui\|Cheng, Mei-Ling\|Jeng, Yung-Ming
PMID:	27305845

1474.
Journal:	Mol Cell Oncol. 2015 May 21;3(1):e1048405.
Title:	Effective MAPK Inhibition is critical for therapeutic responses in colorectal cancer with BRAF mutations.
Author:	Ahronian, Leanne G\|Corcoran, Ryan B
PMID:	27308562

1475.
Journal:	Cancer Res. 2016 Aug 1;76(15):4504-15.
Title:	Molecular Landscape of Acquired Resistance to Targeted Therapy Combinations in BRAF-Mutant Colorectal Cancer.
Author:	Oddo, Daniele\|Sennott, Erin M\|Barault, Ludovic\|Valtorta, Emanuele\|Arena, Sabrina\|Cassingena, Andrea\|Filiciotto, Genny\|Marzolla, Giulia\|Elez, Elena\|van Geel, Robin M J M\|Bartolini, Alice\|Crisafulli, Giovanni\|Boscaro, Valentina\|Godfrey, Jason T\|Buscarino, M
PMID:	27312529

1476.
Journal:	PLoS One. 2016 Jun 17;11(6):e0157830.
Title:	Combination of NK Cells and Cetuximab to Enhance Anti-Tumor Responses in RAS Mutant Metastatic Colorectal Cancer.
Author:	Veluchamy, John Pradeep\|Spanholtz, Jan\|Tordoir, Marleen\|Thijssen, Victor L\|Heideman, Danielle A M\|Verheul, Henk M W\|de Gruijl, Tanja D\|van der Vliet, Hans J
PMID:	27314237

1477.
Journal:	Oncotarget. 2016 Jul 19;7(29):46158-46172.
Title:	Could gut microbiota serve as prognostic biomarker associated with colorectal cancer patients' survival? A pilot study on relevant mechanism.
Author:	Wei, Zhiliang\|Cao, Shougen\|Liu, Shanglong\|Yao, Zengwu\|Sun, Teng\|Li, Yi\|Li, Jiante\|Zhang, Dongfeng\|Zhou, Yanbing
PMID:	27323816

1478.
Journal:	Cancer Discov. 2016 Sep;6(9):963-71.
Title:	MET-Driven Resistance to Dual EGFR and BRAF Blockade May Be Overcome by Switching from EGFR to MET Inhibition in BRAF-Mutated Colorectal Cancer.
Author:	Pietrantonio, Filippo\|Oddo, Daniele\|Gloghini, Annunziata\|Valtorta, Emanuele\|Berenato, Rosa\|Barault, Ludovic\|Caporale, Marta\|Busico, Adele\|Morano, Federica\|Gualeni, Ambra Vittoria\|Alessi, Alessandra\|Siravegna, Giulia\|Perrone, Federica\|Di Bartolomeo, Maria\|
PMID:	27325282

1479.
Journal:	Br J Cancer. 2016 Jun 28;115(1):40-51.
Title:	FAT1: a potential target for monoclonal antibody therapy in colon cancer.
Author:	Pileri, Piero\|Campagnoli, Susanna\|Grandi, Alberto\|Parri, Matteo\|De Camilli, Elisa\|Song, Chaojun\|Ganfini, Luisa\|Lacombe, Aurelien\|Naldi, Ilaria\|Sarmientos, Paolo\|Cinti, Caterina\|Jin, Boquan\|Grandi, Guido\|Viale, Giuseppe\|Terracciano, Luigi\|Grifantini, Renat
PMID:	27328312

1480.
Journal:	Dig Dis. 2016;34(5):574-9.
Title:	Therapeutic Strategies in Diseases of the Digestive Tract - 2015 and Beyond Targeted Therapies in Colon Cancer Today and Tomorrow.
Author:	Pohl, Michael\|Schmiegel, Wolff
PMID:	27332557

1481.
Journal:	Biomol Detect Quantif. 2016 Jun 6;8:29-32.
Title:	Diagnostic RAS mutation analysis by polymerase chain reaction (PCR).
Author:	Cree, Ian A
PMID:	27335808

1482.
Journal:	Mol Cell Proteomics. 2016 Sep;15(9):2924-38.
Title:	Oncogenic KRAS and BRAF Drive Metabolic Reprogramming in Colorectal Cancer.
Author:	Hutton, Josiah E\|Wang, Xiaojing\|Zimmerman, Lisa J\|Slebos, Robbert J C\|Trenary, Irina A\|Young, Jamey D\|Li, Ming\|Liebler, Daniel C
PMID:	27340238

1483.
Journal:	Cancer J. 2016 May-Jun;22(3):156-64.
Title:	Biomarker in Colorectal Cancer.
Author:	Schirripa, Marta\|Lenz, Heinz-Josef
PMID:	27341592

1484.
Journal:	Biochim Biophys Acta. 2016 Aug;1866(1):51-63.
Title:	Targeting the serrated pathway of colorectal cancer with mutation in BRAF.
Author:	Matos, Paulo\|Goncalves, Vania\|Jordan, Peter
PMID:	27345584

1485.
Journal:	Diagn Pathol. 2016 Jun 27;11(1):55.
Title:	Frequency of BRAF V600E mutations in 969 central nervous system neoplasms.
Author:	Behling, Felix\|Barrantes-Freer, Alonso\|Skardelly, Marco\|Nieser, Maike\|Christians, Arne\|Stockhammer, Florian\|Rohde, Veit\|Tatagiba, Marcos\|Hartmann, Christian\|Stadelmann, Christine\|Schittenhelm, Jens
PMID:	27350555

1486.
Journal:	Oncotarget. 2016 Jul 26;7(30):47699-47710.
Title:	BRAFV600E-dependent Mcl-1 stabilization leads to everolimus resistance in colon cancer cells.
Author:	He, Kan\|Chen, Dongshi\|Ruan, Hang\|Li, Xiangyun\|Tong, Jingshan\|Xu, Xiang\|Zhang, Lin\|Yu, Jian
PMID:	27351224

1487.
Journal:	Mol Cancer Res. 2016 Sep;14(9):795-804.
Title:	Distinct Transcriptional Changes and Epithelial-Stromal Interactions Are Altered in Early-Stage Colon Cancer Development.
Author:	Mo, Allen\|Jackson, Stephen\|Varma, Kamini\|Carpino, Alan\|Giardina, Charles\|Devers, Thomas J\|Rosenberg, Daniel W
PMID:	27353028

1488.
Journal:	Discov Med. 2016 May;21(117):341-7.
Title:	Pathological complete response with anti-PD-1 therapy in a patient with microsatellite instable high, BRAF mutant metastatic colon cancer: a case report and review of literature.
Author:	Sehdev, Amikar\|Cramer, Harvey M\|Ibrahim, Ashley A M\|Younger, Anne E\|O'Neil, Bert H
PMID:	27355330

1489.
Journal:	Oncologist. 2016 Aug;21(8):988-94.
Title:	Location of Primary Tumor and Benefit From Anti-Epidermal Growth Factor Receptor Monoclonal Antibodies in Patients With RAS and BRAF Wild-Type Metastatic Colorectal Cancer.
Author:	Moretto, Roberto\|Cremolini, Chiara\|Rossini, Daniele\|Pietrantonio, Filippo\|Battaglin, Francesca\|Mennitto, Alessia\|Bergamo, Francesca\|Loupakis, Fotios\|Marmorino, Federica\|Berenato, Rosa\|Marsico, Valentina Angela\|Caporale, Marta\|Antoniotti, Carlotta\|Masi, Gi
PMID:	27382031

1490.
Journal:	Oncotarget. 2016 Aug 2;7(31):49597-49610.
Title:	Reactivation of ERK and Akt confers resistance of mutant BRAF colon cancer cells to the HSP90 inhibitor AUY922.
Author:	Wang, Chun Yan\|Guo, Su Tang\|Wang, Jia Yu\|Yan, Xu Guang\|Farrelly, Margaret\|Zhang, Yuan Yuan\|Liu, Fen\|Yari, Hamed\|La, Ting\|Lei, Fu Xi\|Jin, Lei\|Zhang, Xu Dong\|Jiang, Chen Chen
PMID:	27391062

1491.
Journal:	Oncotarget. 2016 Aug 23;7(34):55098-55109.
Title:	Tumor LINE-1 methylation level and colorectal cancer location in relation to patient survival.
Author:	Mima, Kosuke\|Nowak, Jonathan A\|Qian, Zhi Rong\|Cao, Yin\|Song, Mingyang\|Masugi, Yohei\|Shi, Yan\|da Silva, Annacarolina\|Gu, Mancang\|Li, Wanwan\|Hamada, Tsuyoshi\|Zhang, Xuehong\|Wu, Kana\|Meyerhardt, Jeffrey A\|Baba, Hideo\|Giovannucci, Edward L\|Chan, Andrew T\|Fuch
PMID:	27391152

1492.
Journal:	Virchows Arch. 2016 Oct;469(4):459-64.
Title:	Challenging a dogma: co-mutations exist in MAPK pathway genes in colorectal cancer.
Author:	Grellety, Thomas\|Gros, Audrey\|Pedeutour, Florence\|Merlio, Jean-Philippe\|Duranton-Tanneur, Valerie\|Italiano, Antoine\|Soubeyran, Isabelle
PMID:	27401719

1493.
Journal:	Oncology. 2016;91(3):162-70.
Title:	Colorectal Cancer with BRAF D594G Mutation Is Not Associated with Microsatellite Instability or Poor Prognosis.
Author:	Amaki-Takao, Misato\|Yamaguchi, Tatsuro\|Natsume, Soichiro\|Iijima, Takeru\|Wakaume, Rika\|Takahashi, Keiichi\|Matsumoto, Hiroshi\|Miyaki, Michiko
PMID:	27404270

1494.
Journal:	BMC Cancer. 2016 Jul 12;16:454.
Title:	Highly sensitive detection of the PIK3CA (H1047R) mutation in colorectal cancer using a novel PCR-RFLP method.
Author:	Li, Wan-Ming\|Hu, Ting-Ting\|Zhou, Lin-Lin\|Feng, Yi-Ming\|Wang, Yun-Yi\|Fang, Jin
PMID:	27405731

1495.
Journal:	BMC Cancer. 2016 Jul 13;16:471.
Title:	SOX2 expression is associated with a cancer stem cell state and down-regulation of CDX2 in colorectal cancer.
Author:	Lundberg, Ida V\|Edin, Sofia\|Eklof, Vincy\|Oberg, Ake\|Palmqvist, Richard\|Wikberg, Maria L
PMID:	27411517

1496.
Journal:	Virchows Arch. 2016 Oct;469(4):395-404.
Title:	HIF-1alpha expression and high microvessel density are characteristic features in serrated colorectal cancer.
Author:	Tuomisto, Anne\|Garcia-Solano, Jose\|Sirnio, Paivi\|Vayrynen, Juha\|Perez-Guillermo, Miguel\|Makinen, Markus J\|Conesa-Zamora, Pablo
PMID:	27421843

1497.
Journal:	Int J Mol Med. 2016 Sep;38(3):687-702.
Title:	Serrated polyposis associated with a family history of colorectal cancer and/or polyps: The preferential location of polyps in the colon and rectum defines two molecular entities.
Author:	Silva, Patricia\|Albuquerque, Cristina\|Lage, Pedro\|Fontes, Vanessa\|Fonseca, Ricardo\|Vitoriano, Ines\|Filipe, Bruno\|Rodrigues, Paula\|Moita, Susana\|Ferreira, Sara\|Sousa, Rita\|Claro, Isabel\|Nobre Leitao, Carlos\|Chaves, Paula\|Dias Pereira, Antonio
PMID:	27430658

1498.
Journal:	Int J Clin Oncol. 2016 Dec;21(6):1091-1101.
Title:	CpG island methylator phenotype is associated with the efficacy of sequential oxaliplatin- and irinotecan-based chemotherapy and EGFR-related gene mutation in Japanese patients with metastatic colorectal cancer.
Author:	Zhang, Xiaofei\|Shimodaira, Hideki\|Soeda, Hiroshi\|Komine, Keigo\|Takahashi, Hidekazu\|Ouchi, Kota\|Inoue, Masahiro\|Takahashi, Masanobu\|Takahashi, Shin\|Ishioka, Chikashi
PMID:	27435270

1499.
Journal:	Am J Surg Pathol. 2016 Oct;40(10):1390-9.
Title:	MLH1-deficient Colorectal Carcinoma With Wild-type BRAF and MLH1 Promoter Hypermethylation Harbor KRAS Mutations and Arise From Conventional Adenomas.
Author:	Farchoukh, Lama\|Kuan, Shih-Fan\|Dudley, Beth\|Brand, Randall\|Nikiforova, Marina\|Pai, Reetesh K
PMID:	27438990

1500.
Journal:	Gastroenterology. 2016 Nov;151(5):870-878.e3.
Title:	Clinical and Molecular Characteristics of Post-Colonoscopy Colorectal Cancer: A Population-based Study.
Author:	Stoffel, Elena M\|Erichsen, Rune\|Froslev, Trine\|Pedersen, Lars\|Vyberg, Mogens\|Koeppe, Erika\|Crockett, Seth D\|Hamilton, Stanley R\|Sorensen, Henrik T\|Baron, John A
PMID:	27443823

1501.
Journal:	BMC Cancer. 2016 Jul 26;16:531.
Title:	Pro-survival responses to the dual inhibition of anti-apoptotic Bcl-2 family proteins and mTOR-mediated signaling in hypoxic colorectal carcinoma cells.
Author:	Risberg, Karianne\|Redalen, Kathrine Roe\|Sonstevold, Linda\|Bjornetro, Tonje\|Solvernes, Janne\|Ree, Anne Hansen
PMID:	27461218

1502.
Journal:	Cancer Chemother Pharmacol. 2016 Sep;78(3):585-93.
Title:	Multicenter phase II study of combination therapy with cetuximab and S-1 in patients with KRAS exon 2 wild-type unresectable colorectal cancer previously treated with irinotecan, oxaliplatin, and fluoropyrimidines (KSCC 0901 study).
Author:	Takahashi, Takao\|Emi, Yasunori\|Oki, Eiji\|Kobayashi, Kazuma\|Tsuji, Akihito\|Shimokawa, Mototsugu\|Tanaka, Takaho\|Akagi, Yoshito\|Ogata, Yutaka\|Baba, Hideo\|Yoshida, Kazuhiro\|Natsugoe, Shoji\|Maehara, Yoshihiko
PMID:	27468920

1503.
Journal:	Exp Mol Med. 2016 Jul 29;48(7):e249.
Title:	Sur8 mediates tumorigenesis and metastasis in colorectal cancer.
Author:	Lee, Young-Mi\|Kaduwal, Saluja\|Lee, Kug Hwa\|Park, Jong-Chan\|Jeong, Woo-Jeong\|Choi, Kang-Yell
PMID:	27469030

1504.
Journal:	Protein Cell. 2016 Aug;7(8):571-85.
Title:	Ursolic acid synergistically enhances the therapeutic effects of oxaliplatin in colorectal cancer.
Author:	Shan, Jianzhen\|Xuan, Yanyan\|Zhang, Qi\|Zhu, Chunpeng\|Liu, Zhen\|Zhang, Suzhan
PMID:	27472952

1505.
Journal:	Gastroenterology. 2016 Nov;151(5):879-892.e4.
Title:	Regular Aspirin Use Associates With Lower Risk of Colorectal Cancers With Low Numbers of Tumor-Infiltrating Lymphocytes.
Author:	Cao, Yin\|Nishihara, Reiko\|Qian, Zhi Rong\|Song, Mingyang\|Mima, Kosuke\|Inamura, Kentaro\|Nowak, Jonathan A\|Drew, David A\|Lochhead, Paul\|Nosho, Katsuhiko\|Morikawa, Teppei\|Zhang, Xuehong\|Wu, Kana\|Wang, Molin\|Garrett, Wendy S\|Giovannucci, Edward L\|Fuchs, Charle
PMID:	27475305

1506.
Journal:	PLoS One. 2016 Aug 2;11(8):e0160599.
Title:	Cost-Effectiveness Analysis of Different Genetic Testing Strategies for Lynch Syndrome in Taiwan.
Author:	Chen, Ying-Erh\|Kao, Sung-Shuo\|Chung, Ren-Hua
PMID:	27482709

1507.
Journal:	Anal Chim Acta. 2016 Aug 24;933:144-55.
Title:	Quantitative analysis of wild-type and V600E mutant BRAF proteins in colorectal carcinoma using immunoenrichment and targeted mass spectrometry.
Author:	Chen, Hang\|Hsiao, Yung-Chin\|Chiang, Sum-Fu\|Wu, Chia-Chun\|Lin, Yu-Tsun\|Liu, Hsuan\|Zhao, Hong\|Chen, Jinn-Shiun\|Chang, Yu-Sun\|Yu, Jau-Song
PMID:	27497007

1508.
Journal:	J Pathol Clin Res. 2015 Oct 28;2(1):21-31.
Title:	The infiltration, and prognostic importance, of Th1 lymphocytes vary in molecular subgroups of colorectal cancer.
Author:	Ling, Agnes\|Lundberg, Ida V\|Eklof, Vincy\|Wikberg, Maria L\|Oberg, Ake\|Edin, Sofia\|Palmqvist, Richard
PMID:	27499912

1509.
Journal:	J Pathol Clin Res. 2016 Apr 22;2(3):127-37.
Title:	The molecular characteristics of colonic neoplasms in serrated polyposis: a systematic review and meta-analysis.
Author:	He, Emily Y\|Wyld, Lucy\|Sloane, Mathew A\|Canfell, Karen\|Ward, Robyn L
PMID:	27499922

1510.
Journal:	J Pathol Clin Res. 2016 Apr 15;2(3):166-74.
Title:	Somatic mutation profiles in primary colorectal cancers and matching ovarian metastases: Identification of driver and passenger mutations.
Author:	Crobach, Stijn\|Ruano, Dina\|van Eijk, Ronald\|Schrumpf, Melanie\|Fleuren, Gertjan\|van Wezel, Tom\|Morreau, Hans
PMID:	27499925

1511.
Journal:	Int J Cancer. 2016 Dec 1;139(11):2493-501.
Title:	Molecular differences in the microsatellite stable phenotype between left-sided and right-sided colorectal cancer.
Author:	Takahashi, Yayoi\|Sugai, Tamotsu\|Habano, Wataru\|Ishida, Kazuyuki\|Eizuka, Makoto\|Otsuka, Koki\|Sasaki, Akira\|Takayuki Matsumoto\|Morikawa, Takanori\|Unno, Michiaki\|Suzuki, Hiromu
PMID:	27509333

1512.
Journal:	BMC Cancer. 2016 Aug 12;16:624.
Title:	IAP antagonists Birinapant and AT-406 efficiently synergise with either TRAIL, BRAF, or BCL-2 inhibitors to sensitise BRAFV600E colorectal tumour cells to apoptosis.
Author:	Perimenis, Philippos\|Galaris, Apostolos\|Voulgari, Alexandra\|Prassa, Margarita\|Pintzas, Alexander
PMID:	27520705

1513.
Journal:	Gastroenterology. 2016 Nov;151(5):961-972.
Title:	Epigenetic Homogeneity Within Colorectal Tumors Predicts Shorter Relapse-Free and Overall Survival Times for Patients With Locoregional Cancer.
Author:	Martinez-Cardus, Anna\|Moran, Sebastian\|Musulen, Eva\|Moutinho, Catia\|Manzano, Jose L\|Martinez-Balibrea, Eva\|Tierno, Montserrat\|Elez, Elena\|Landolfi, Stefania\|Lorden, Patricia\|Arribas, Carles\|Muller, Fabian\|Bock, Christoph\|Tabernero, Josep\|Esteller, Manel
PMID:	27521480

1514.
Journal:	Acta Medica (Hradec Kralove). 2016;59(2):54-8.
Title:	Carrier molecules and extraction of circulating tumor DNA for next generation sequencing in colorectal cancer.
Author:	Beranek, Martin\|Sirak, Igor\|Vosmik, Milan\|Petera, Jiri\|Drastikova, Monika\|Palicka, Vladimir
PMID:	27526306

1515.
Journal:	Cancer Biomark. 2016 Jun 24;17(2):133-43.
Title:	KRAS, BRAF oncogene mutations and tissue specific promoter hypermethylation of tumor suppressor SFRP2, DAPK1, MGMT, HIC1 and p16 genes in colorectal cancer patients.
Author:	Bagci, Binnur\|Sari, Musa\|Karadayi, Kursat\|Turan, Mustafa\|Ozdemir, Ozturk\|Bagci, Gokhan
PMID:	27540971

1516.
Journal:	J Pediatr Surg. 2016 Nov;51(11):1812-1817.
Title:	Colorectal cancer in the very young: a comparative study of tumor markers, pathology and survival in early onset and adult onset patients.
Author:	Khan, Sajid A\|Morris, Melinda\|Idrees, Kamran\|Gimbel, Mark I\|Rosenberg, Shoshana\|Zeng, Zhaoshi\|Li, Fangyong\|Gan, Geliang\|Shia, Jinru\|LaQuaglia, Michael P\|Paty, Philip B
PMID:	27558481

1517.
Journal:	BMC Cancer. 2016 Aug 25;16(1):683.
Title:	High sensitivity isoelectric focusing to establish a signaling biomarker for the diagnosis of human colorectal cancer.
Author:	Padhan, Narendra\|Nordling, Torbjorn E M\|Sundstrom, Magnus\|Akerud, Peter\|Birgisson, Helgi\|Nygren, Peter\|Nelander, Sven\|Claesson-Welsh, Lena
PMID:	27562229

1518.
Journal:	Oncotarget. 2016 Dec 20;7(51):84003-84016.
Title:	Two subtypes of colorectal tumor with distinct molecular features in familial adenomatous polyposis.
Author:	Takane, Kiyoko\|Matsusaka, Keisuke\|Ota, Satoshi\|Fukuyo, Masaki\|Yue, Yao\|Nishimura, Motoi\|Sakai, Eiji\|Matsushita, Kazuyuki\|Miyauchi, Hideaki\|Aburatani, Hiroyuki\|Nakatani, Yukio\|Takayama, Tadatoshi\|Matsubara, Hisahiro\|Akagi, Kiwamu\|Kaneda, Atsushi
PMID:	27563825

1519.
Journal:	Surg Oncol. 2016 Sep;25(3):190-9.
Title:	Molecular markers of prognosis and therapeutic targets in metastatic colorectal cancer.
Author:	Ronnekleiv-Kelly, Sean M\|Burkhart, Richard A\|Pawlik, Timothy M
PMID:	27566022

1520.
Journal:	J BUON. 2016 May-Jun;21(3):618-25.
Title:	Diagnostic value of immunohistochemistry for the detection of the BRAF V600E mutation in colorectal carcinoma.
Author:	Ioannou, Maria\|Papamichali, Roidoula\|Samara, Maria\|Paraskeva, Efrosini\|Papacharalambous, Constantina\|Baxevanidou, Korina\|Koukoulis, George
PMID:	27569082

1521.
Journal:	World J Gastroenterol. 2016 Aug 14;22(30):6944-54.
Title:	Prognostic and predictive biomarkers in metastatic colorectal cancer anti-EGFR therapy.
Author:	Lo Nigro, Cristiana\|Ricci, Vincenzo\|Vivenza, Daniela\|Granetto, Cristina\|Fabozzi, Teresa\|Miraglio, Emanuela\|Merlano, Marco C
PMID:	27570430

1522.
Journal:	Arch Pharm (Weinheim). 2016 Oct;349(10):808-815.
Title:	Identification and Characterization of Small-Molecule Inhibitors to Selectively Target the DFG-in over the DFG-out Conformation of the B-Raf Kinase V600E Mutant in Colorectal Cancer.
Author:	Yao, Huixiang\|Sun, Qun\|Zhu, Jinshui
PMID:	27624806

1523.
Journal:	Cold Spring Harb Mol Case Stud. 2016 Sep;2(5):a001016.
Title:	Testing ERBB2 p.L755S kinase domain mutation as a druggable target in a patient with advanced colorectal cancer.
Author:	Aung, Kyaw L\|Stockley, Tracy L\|Serra, Stefano\|Kamel-Reid, Suzanne\|Bedard, Philippe L\|Siu, Lillian L
PMID:	27626067

1524.
Journal:	Anticancer Res. 2016 Sep;36(9):4805-11.
Title:	Prognostic Role of BRAF Mutations in Colorectal Cancer Liver Metastases.
Author:	Pikoulis, Emmanouil\|Margonis, Georgios A\|Andreatos, Nikolaos\|Sasaki, Kazunari\|Angelou, Anastasios\|Polychronidis, Georgios\|Pikouli, Anastasia\|Riza, Elena\|Pawlik, Timothy M\|Antoniou, Efstathios
PMID:	27630332

1525.
Journal:	Pathologe. 2016 Nov;37(Suppl 2):180-185.
Title:	[Prognostic biomarkers for metastatic colorectal cancer].
Author:	Neumann, J H L
PMID:	27638531

1526.
Journal:	Pathologe. 2016 Nov;37(Suppl 2):186-190.
Title:	[Pathogenetic aspects in precursor lesions of gastrointestinal tumors].
Author:	Rau, T
PMID:	27638535

1527.
Journal:	Tumori. 2016 Dec 1;102(6):541-547.
Title:	How the lab is changing our view of colorectal cancer.
Author:	Cremolini, Chiara\|Pietrantonio, Filippo
PMID:	27647226

1528.
Journal:	Mol Cancer Res. 2016 Dec;14(12):1204-1216.
Title:	MEK and TAK1 Regulate Apoptosis in Colon Cancer Cells with KRAS-Dependent Activation of Proinflammatory Signaling.
Author:	McNew, Kelsey L\|Whipple, William J\|Mehta, Anita K\|Grant, Trevor J\|Ray, Leah\|Kenny, Connor\|Singh, Anurag
PMID:	27655129

1529.
Journal:	Clin Med Insights Pathol. 2016 Sep 7;9:19-28.
Title:	Oncogene Mutations in Colorectal Polyps Identified in the Norwegian Colorectal Cancer Prevention (NORCCAP) Screening Study.
Author:	Lorentzen, Jon A\|Grzyb, Krzysztof\|De Angelis, Paula M\|Hoff, Geir\|Eide, Tor J\|Andresen, Per Arne
PMID:	27656095

1530.
Journal:	Oncotarget. 2016 Oct 25;7(43):70589-70600.
Title:	RNF43 and ZNRF3 are commonly altered in serrated pathway colorectal tumorigenesis.
Author:	Bond, Catherine E\|McKeone, Diane M\|Kalimutho, Murugan\|Bettington, Mark L\|Pearson, Sally-Ann\|Dumenil, Troy D\|Wockner, Leesa F\|Burge, Matthew\|Leggett, Barbara A\|Whitehall, Vicki L J
PMID:	27661107

1531.
Journal:	Cancer Sci. 2016 Dec;107(12):1843-1850.
Title:	Randomized study of FOLFIRI plus either panitumumab or bevacizumab for wild-type KRAS colorectal cancer-WJOG 6210G.
Author:	Shitara, Kohei\|Yonesaka, Kimio\|Denda, Tadamichi\|Yamazaki, Kentaro\|Moriwaki, Toshikazu\|Tsuda, Masahiro\|Takano, Toshimi\|Okuda, Hiroyuki\|Nishina, Tomohiro\|Sakai, Kazuko\|Nishio, Kazuto\|Tokunaga, Shoji\|Yamanaka, Takeharu\|Boku, Narikazu\|Hyodo, Ichinosuke\|Muro,
PMID:	27712015

1532.
Journal:	Oncotarget. 2016 Nov 8;7(45):73876-73887.
Title:	Genomic profiling of stage II and III colon cancers reveals APC mutations to be associated with survival in stage III colon cancer patients.
Author:	van den Broek, Evert\|Krijgsman, Oscar\|Sie, Daoud\|Tijssen, Marianne\|Mongera, Sandra\|van de Wiel, Mark A\|Belt, Eric J Th\|den Uil, Sjoerd H\|Bril, Herman\|Stockmann, Hein B A C\|Ylstra, Bauke\|Carvalho, Beatriz\|Meijer, Gerrit A\|Fijneman, Remond J A
PMID:	27729614

1533.
Journal:	J Transl Med. 2016 Oct 13;14(1):292.
Title:	Prognostic impact of KRAS, NRAS, BRAF, and PIK3CA mutations in primary colorectal carcinomas: a population-based study.
Author:	Palomba, Grazia\|Doneddu, Valentina\|Cossu, Antonio\|Paliogiannis, Panagiotis\|Manca, Antonella\|Casula, Milena\|Colombino, Maria\|Lanzillo, Annamaria\|Defraia, Efisio\|Pazzola, Antonio\|Sanna, Giovanni\|Putzu, Carlo\|Ortu, Salvatore\|Scartozzi, Mario\|Ionta, Maria Ter
PMID:	27737711

1534.
Journal:	Cancer Immunol Res. 2016 Nov;4(11):927-935.
Title:	MicroRNA let-7, T Cells, and Patient Survival in Colorectal Cancer.
Author:	Dou, Ruoxu\|Nishihara, Reiko\|Cao, Yin\|Hamada, Tsuyoshi\|Mima, Kosuke\|Masuda, Atsuhiro\|Masugi, Yohei\|Shi, Yan\|Gu, Mancang\|Li, Wanwan\|da Silva, Annacarolina\|Nosho, Katsuhiko\|Zhang, Xuehong\|Meyerhardt, Jeffrey A\|Giovannucci, Edward L\|Chan, Andrew T\|Fuchs, Char
PMID:	27737877

1535.
Journal:	Lancet Oncol. 2016 Dec;17(12):1709-1719.
Title:	Prognosis of patients with peritoneal metastatic colorectal cancer given systemic therapy: an analysis of individual patient data from prospective randomised trials from the Analysis and Research in Cancers of the Digestive System (ARCAD) database.
Author:	Franko, Jan\|Shi, Qian\|Meyers, Jeffrey P\|Maughan, Timothy S\|Adams, Richard A\|Seymour, Matthew T\|Saltz, Leonard\|Punt, Cornelis J A\|Koopman, Miriam\|Tournigand, Christophe\|Tebbutt, Niall C\|Diaz-Rubio, Eduardo\|Souglakos, John\|Falcone, Alfredo\|Chibaudel, Benois
PMID:	27743922

1536.
Journal:	J Gastrointest Oncol. 2016 Oct;7(5):687-704.
Title:	RAS and BRAF in metastatic colorectal cancer management.
Author:	Gong, Jun\|Cho, May\|Fakih, Marwan
PMID:	27747083

1537.
Journal:	J Gastrointest Oncol. 2016 Oct;7(5):705-712.
Title:	Beyond RAS and BRAF: a target rich disease that is ripe for picking.
Author:	Friedrich, Tyler\|Leong, Stephen\|Lieu, Christopher H
PMID:	27747084

1538.
Journal:	J Gastrointest Oncol. 2016 Oct;7(5):713-720.
Title:	Biomarkers for immune therapy in colorectal cancer: mismatch-repair deficiency and others.
Author:	Bupathi, Manojkumar\|Wu, Christina
PMID:	27747085

1539.
Journal:	Br J Cancer. 2016 Nov 8;115(10):1215-1222.
Title:	Impact of tumour RAS/BRAF status in a first-line study of panitumumab + FOLFIRI in patients with metastatic colorectal cancer.
Author:	Karthaus, Meinolf\|Hofheinz, Ralf-Dieter\|Mineur, Laurent\|Letocha, Henry\|Greil, Richard\|Thaler, Josef\|Fernebro, Eva\|Oliner, Kelly S\|Boedigheimer, Michael\|Twomey, Brian\|Zhang, Ying\|Demonty, Gaston\|Kohne, Claus-Henning
PMID:	27764839

1540.
Journal:	Mol Cancer Ther. 2016 Dec;15(12):3015-3027.
Title:	Mutant BRAF Upregulates MCL-1 to Confer Apoptosis Resistance that Is Reversed by MCL-1 Antagonism and Cobimetinib in Colorectal Cancer.
Author:	Kawakami, Hisato\|Huang, Shengbing\|Pal, Krishnendu\|Dutta, Shamit K\|Mukhopadhyay, Debabrata\|Sinicrope, Frank A
PMID:	27765849

1541.
Journal:	Cancer Discov. 2016 Dec;6(12):OF6.
Title:	Triple Therapy Improves Colorectal Cancer Response.
Author:
PMID:	27770002

1542.
Journal:	World J Clin Oncol. 2016 Oct 10;7(5):340-351.
Title:	Oncogenic fingerprint of epidermal growth factor receptor pathway and emerging epidermal growth factor receptor blockade resistance in colorectal cancer.
Author:	Sobani, Zain A\|Sawant, Ashwin\|Jafri, Mikram\|Correa, Amit Keith\|Sahin, Ibrahim Halil
PMID:	27777877

1543.
Journal:	Zhonghua Wei Chang Wai Ke Za Zhi. 2016 Oct 25;19(10):1197-1200.
Title:	[Research progress of serrated polyposis syndrome].
Author:	Dong, Shihao\|Chen, Jingsong
PMID:	27781259

1544.
Journal:	Anticancer Res. 2016 Oct;36(10):5315-5324.
Title:	KRAS Mutant Status, p16 and beta-catenin Expression May Predict Local Recurrence in Patients Who Underwent Transanal Endoscopic Microsurgery (TEMS) for Stage I Rectal Cancer.
Author:	Sideris, Michail\|Moorhead, Jane\|Diaz-Cano, Salvador\|Bjarnason, Ingvar\|Haji, Amyn\|Papagrigoriadis, Savvas
PMID:	27798894

1545.
Journal:	Br J Cancer. 2016 Nov 22;115(11):1359-1366.
Title:	No association of CpG island methylator phenotype and colorectal cancer survival: population-based study.
Author:	Jia, Min\|Jansen, Lina\|Walter, Viola\|Tagscherer, Katrin\|Roth, Wilfried\|Herpel, Esther\|Kloor, Matthias\|Blaker, Hendrik\|Chang-Claude, Jenny\|Brenner, Hermann\|Hoffmeister, Michael
PMID:	27811854

1546.
Journal:	Oncotarget. 2016 Dec 6;7(49):80888-80900.
Title:	FoxO3a confers cetuximab resistance in RAS wild-type metastatic colorectal cancer through c-Myc.
Author:	Yu, Yiyi\|Guo, Mengzhou\|Wei, Ye\|Yu, Shan\|Li, Hong\|Wang, Yan\|Xu, Xiaojing\|Cui, Yuehong\|Tian, Jiawen\|Liang, Li\|Peng, Ke\|Liu, Tianshu
PMID:	27825133

1547.
Journal:	Cancer Treat Rev. 2016 Dec;51:19-26.
Title:	The evolving role of microsatellite instability in colorectal cancer: A review.
Author:	Gelsomino, Fabio\|Barbolini, Monica\|Spallanzani, Andrea\|Pugliese, Giuseppe\|Cascinu, Stefano
PMID:	27838401

1548.
Journal:	Int J Biochem Cell Biol. 2016 Dec;81(Pt A):121-132.
Title:	Multimodal tumor suppression by miR-302 cluster in melanoma and colon cancer.
Author:	Maadi, Hamid\|Moshtaghian, Abdolvahab\|Taha, Masoumeh Fakhr\|Mowla, Seyed Javad\|Kazeroonian, Asiye\|Haass, Nikolas K\|Javeri, Arash
PMID:	27840154

1549.
Journal:	Oncotarget. 2016 Dec 20;7(51):85349-85364.
Title:	Enumeration and targeted analysis of KRAS, BRAF and PIK3CA mutations in CTCs captured by a label-free platform: Comparison to ctDNA and tissue in metastatic colorectal cancer.
Author:	Kidess-Sigal, Evelyn\|Liu, Haiyan E\|Triboulet, Melanie M\|Che, James\|Ramani, Vishnu C\|Visser, Brendan C\|Poultsides, George A\|Longacre, Teri A\|Marziali, Andre\|Vysotskaia, Valentina\|Wiggin, Matthew\|Heirich, Kyra\|Hanft, Violet\|Keilholz, Ulrich\|Tinhofer, Ingebo
PMID:	27863403

1550.
Journal:	BMC Cancer. 2016 Nov 18;16(1):902.
Title:	Hypoxic resistance of KRAS mutant tumor cells to 3-Bromopyruvate is counteracted by Prima-1 and reversed by N-acetylcysteine.
Author:	Orue, Andrea\|Chavez, Valery\|Strasberg-Rieber, Mary\|Rieber, Manuel
PMID:	27863474

1551.
Journal:	Oncologist. 2016 Dec;21(12):1509-1521.
Title:	Relationship Between Metformin Use and Recurrence and Survival in Patients With Resected Stage III Colon Cancer Receiving Adjuvant Chemotherapy: Results From North Central Cancer Treatment Group N0147 (Alliance).
Author:	Singh, Preet Paul\|Shi, Qian\|Foster, Nathan R\|Grothey, Axel\|Nair, Suresh G\|Chan, Emily\|Shields, Anthony F\|Goldberg, Richard M\|Gill, Sharlene\|Kahlenberg, Morton S\|Sinicrope, Frank A\|Sargent, Daniel J\|Alberts, Steven R
PMID:	27881709

1552.
Journal:	Oncol Lett. 2016 Nov;12(5):3356-3362.
Title:	Role of specific DNA mutations in the peripheral blood of colorectal cancer patients for the assessment of tumor stage and residual disease following tumor resection.
Author:	Norcic, Gregor\|Jelenc, Franc\|Cerkovnik, Petra\|Stegel, Vida\|Novakovic, Srdjan
PMID:	27900004

1553.
Journal:	Mol Clin Oncol. 2016 Nov;5(5):579-582.
Title:	Favorable control of advanced colon adenocarcinoma with severe bone marrow metastasis: A case report.
Author:	Hanamura, Fumiyasu\|Shibata, Yoshihiro\|Shirakawa, Tsuyoshi\|Kuwayama, Miyuki\|Oda, Hisanobu\|Ariyama, Hiroshi\|Taguchi, Kenichi\|Esaki, Taito\|Baba, Eishi
PMID:	27900088

1554.
Journal:	Int J Mol Sci. 2016 Dec 1;17(12). pii: ijms17122015.
Title:	High Intra- and Inter-Tumoral Heterogeneity of RAS Mutations in Colorectal Cancer.
Author:	Jeantet, Marion\|Tougeron, David\|Tachon, Gaelle\|Cortes, Ulrich\|Archambaut, Celine\|Fromont, Gaelle\|Karayan-Tapon, Lucie
PMID:	27916952

1555.
Journal:	J Oncol Pract. 2016 Dec;12(12):1219-1228.
Title:	Role of Biologics in First-Line Treatment of Colorectal Cancer.
Author:	Mahipal, Amit\|Grothey, Axel
PMID:	27943689

1556.
Journal:	Front Oncol. 2016 Nov 29;6:252.
Title:	Colorectal Choriocarcinoma in a Patient with Probable Lynch Syndrome.
Author:	Koelzer, Viktor H\|Steuer, Karl\|Gross, Ulrike Camenisch\|Zimmermann, Dieter\|Paasinen-Sohns, Aino\|Mertz, Kirsten D\|Cathomas, Gieri
PMID:	27965933

1557.
Journal:	Onco Targets Ther. 2016 Dec 7;9:7385-7395.
Title:	Association between proto-oncogene mutations and clinicopathologic characteristics and overall survival in colorectal cancer in East Azerbaijan, Iran.
Author:	Dolatkhah, Roya\|Somi, Mohammad Hossein\|Asvadi Kermani, Iraj\|Bonyadi, Morteza\|Sepehri, Bita\|Boostani, Kamal\|Azadbakht, Saleh\|Fotouhi, Nikou\|Farassati, Faris\|Dastgiri, Saeed
PMID:	27994469

1558.
Journal:	Genome Med. 2016 Dec 22;8(1):136.
Title:	Genomic landscape of colorectal cancer in Japan: clinical implications of comprehensive genomic sequencing for precision medicine.
Author:	Nagahashi, Masayuki\|Wakai, Toshifumi\|Shimada, Yoshifumi\|Ichikawa, Hiroshi\|Kameyama, Hitoshi\|Kobayashi, Takashi\|Sakata, Jun\|Yagi, Ryoma\|Sato, Nobuaki\|Kitagawa, Yuko\|Uetake, Hiroyuki\|Yoshida, Kazuhiro\|Oki, Eiji\|Kudo, Shin-Ei\|Izutsu, Hiroshi\|Kodama, Keisuke\|
PMID:	28007036

1559.
Journal:	Curr Oncol. 2016 Dec;23(6):e571-e575.
Title:	Personalized oncogenomics in the management of gastrointestinal carcinomas-early experiences from a pilot study.
Author:	Sheffield, B S\|Tessier-Cloutier, B\|Li-Chang, H\|Shen, Y\|Pleasance, E\|Kasaian, K\|Li, Y\|Jones, S J M\|Lim, H J\|Renouf, D J\|Huntsman, D G\|Yip, S\|Laskin, J\|Marra, M\|Schaeffer, D F
PMID:	28050146

1560.
Journal:	J Gastrointest Oncol. 2016 Dec;7(6):882-902.
Title:	Molecular spectrum of KRAS, NRAS, BRAF, PIK3CA, TP53, and APC somatic gene mutations in Arab patients with colorectal cancer: determination of frequency and distribution pattern.
Author:	Al-Shamsi, Humaid O\|Jones, Jeremy\|Fahmawi, Yazan\|Dahbour, Ibrahim\|Tabash, Aziz\|Abdel-Wahab, Reham\|Abousamra, Ahmed O S\|Shaw, Kenna R\|Xiao, Lianchun\|Hassan, Manal M\|Kipp, Benjamin R\|Kopetz, Scott\|Soliman, Amr S\|McWilliams, Robert R\|Wolff, Robert A
PMID:	28078112

1561.
Journal:	World J Gastroenterol. 2016 Dec 28;22(48):10680-10686.
Title:	Efficiency of olaparib in colorectal cancer patients with an alteration of the homologous repair protein.
Author:	Ghiringhelli, Francois\|Richard, Corentin\|Chevrier, Sandy\|Vegran, Frederique\|Boidot, Romain
PMID:	28082821

1562.
Journal:	Oncol Lett. 2016 Dec;12(6):4427-4434.
Title:	Impact of microsatellite status on chemotherapy for colorectal cancer patients with KRAS or BRAF mutation.
Author:	Huang, Chi-Jung\|Huang, Shih-Hung\|Chien, Chih-Cheng\|Lee, Henry Hsin-Chung\|Yang, Shung-Haur\|Chang, Chun-Chao\|Lee, Chia-Long
PMID:	28101205

1563.
Journal:	Gan To Kagaku Ryoho. 2016 Nov;43(12):1693-1695.
Title:	[Evaluation of BRAF V600E Mutations in High-Level Microsatellite Instability(MSI-H)Colon Cancer - Comparison Between Genetic Testing and Immunohistochemical Staining].
Author:	Sakimoto, Takehiko\|Chika, Noriyasu\|Suzuki, Okihide\|Ishibashi, Keiichiro\|Tachikawa, Tetsuhiko\|Akagi, Kiwamu\|Eguchi, Hidetaka\|Okazaki, Yasushi\|Ishida, Hideyuki
PMID:	28133101

1564.
Journal:	Gan To Kagaku Ryoho. 2016 Nov;43(12):1800-1802.
Title:	[A Case of Metastatic Colon Cancer Dramatically Affected by Anti-EGFR Antibody Therapy].
Author:	Yagi, Ryoma\|Shimada, Yoshifumi\|Miura, Kohei\|Tajima, Yosuke\|Okamura, Takuma\|Nakano, Masato\|Ichikawa, Hiroshi\|Nagahashi, Masayuki\|Sakata, Jun\|Kobayashi, Takashi\|Kameyama, Hitoshi\|Wakai, Toshifumi\|Nogami, Hitoshi\|Maruyama, Satoshi\|Takii, Yasumasa
PMID:	28133136

1565.
Journal:	Gan To Kagaku Ryoho. 2016 Nov;43(12):2280-2282.
Title:	[A Systematic Analysis of Oncogene and Tumor Suppressor Genes for Panitumumab-Resistant Rectal Cancer with Wild RAS Gene - A Case Report].
Author:	Tajima, Yosuke\|Shimada, Yoshifumi\|Yagi, Ryoma\|Okamura, Takuma\|Nakano, Masato\|Kameyama, Hitoshi\|Nogami, Hitoshi\|Maruyama, Satoshi\|Takii, Yasumasa\|Miura, Kohei\|Ichikawa, Hiroshi\|Nagahashi, Masayuki\|Sakata, Jun\|Kobayashi, Takashi\|Wakai, Toshifumi
PMID:	28133295

1566.
Journal:	Gan To Kagaku Ryoho. 2016 Nov;43(12):2307-2309.
Title:	[A Case of Metastatic Colorectal Cancer with HER2 Overexpression/Amplification].
Author:	Matsumoto, Akio\|Shimada, Yoshifumi\|Yagi, Ryoma\|Miura, Kohei\|Tajima, Yosuke\|Okamura, Takuma\|Nakano, Masato\|Kameyama, Hitoshi\|Nogami, Hitoshi\|Maruyama, Satoshi\|Takii, Yasumasa\|Ichikawa, Hiroshi\|Sakata, Jun\|Kobayashi, Takashi\|Wakai, Toshifumi
PMID:	28133304

1567.
Journal:	J Cancer Res Ther. 2016 Dec;12(Supplement):C191-C198.
Title:	Evaluation and identification of factors related to KRAS and BRAF gene mutations in colorectal cancer: A meta-analysis.
Author:	Lin, Li\|Chen, Guang-Yong\|Xu, Chun-Wei\|Wang, Hai-Yan\|Wu, Yong-Fang\|Fang, Mei-Yu
PMID:	28230016

1568.
Journal:	Acta Med Litu. 2016;23(1):24-34.
Title:	Significance of KRAS, NRAS, BRAF and PIK3CA mutations in metastatic colorectal cancer patients receiving Bevacizumab: a single institution experience.
Author:	Baltruskeviciene, Edita\|Mickys, Ugnius\|Zvirblis, Tadas\|Stulpinas, Rokas\|Pipiriene Zelviene, Terese\|Aleknavicius, Eduardas
PMID:	28356789

1569.
Journal:	ESMO Open. 2017 Feb 20;1(6):e000086.
Title:	Clinical activity and tolerability of FOLFIRI and cetuximab in elderly patients with metastatic colorectal cancer in the CAPRI-GOIM first-line trial.
Author:	Martinelli, E\|Cardone, C\|Troiani, T\|Normanno, N\|Pisconti, S\|Sforza, V\|Bordonaro, A R\|Rachiglio, A M\|Lambiase, M\|Latiano, T P\|Modoni, G\|Cordio, S\|Giuliani, F\|Biglietto, M\|Montesarchio, V\|Barone, C\|Tonini, G\|Cinieri, S\|Febbraro, A\|Rizzi, D\|De Vita, F\|Orditu
PMID:	28848656

1570.
Journal:	React Oxyg Species (Apex). 2016 Mar;1(2):141-156.
Title:	Vitamin C, a Multi-Tasking Molecule, Finds a Molecular Target in Killing Cancer Cells.
Author:	Li, Robert
PMID:	29780883

1571.
Journal:	Gut. 2017 Jan;66(1):97-106.
Title:	Clinicopathological and molecular features of sessile serrated adenomas with dysplasia or carcinoma.
Author:	Bettington, Mark\|Walker, Neal\|Rosty, Christophe\|Brown, Ian\|Clouston, Andrew\|McKeone, Diane\|Pearson, Sally-Ann\|Leggett, Barbara\|Whitehall, Vicki
PMID:	26475632

1572.
Journal:	Ann Surg. 2017 Mar;265(3):539-546.
Title:	The Lymphocyte-to-Monocyte Ratio is a Superior Predictor of Overall Survival in Comparison to Established Biomarkers of Resectable Colorectal Cancer.
Author:	Chan, Joseph C Y\|Chan, David L\|Diakos, Connie I\|Engel, Alexander\|Pavlakis, Nick\|Gill, Anthony\|Clarke, Stephen J
PMID:	27070934

1573.
Journal:	Gut. 2017 Aug;66(8):1463-1473.
Title:	Tumour CD274 (PD-L1) expression and T cells in colorectal cancer.
Author:	Masugi, Yohei\|Nishihara, Reiko\|Yang, Juhong\|Mima, Kosuke\|da Silva, Annacarolina\|Shi, Yan\|Inamura, Kentaro\|Cao, Yin\|Song, Mingyang\|Nowak, Jonathan A\|Liao, Xiaoyun\|Nosho, Katsuhiko\|Chan, Andrew T\|Giannakis, Marios\|Bass, Adam J\|Hodi, F Stephen\|Freeman, Gordo
PMID:	27196573

1574.
Journal:	Appl Immunohistochem Mol Morphol. 2017 Jul;25(6):399-406.
Title:	Small Bowel Adenocarcinoma Frequently Exhibits Lynch Syndrome-associated Mismatch Repair Protein Deficiency But Does Not Harbor Sporadic MLH1 Deficiency.
Author:	Xia, Michelle\|Singhi, Aatur D\|Dudley, Beth\|Brand, Randall\|Nikiforova, Marina\|Pai, Reetesh K
PMID:	27258561

1575.
Journal:	J Gastroenterol Hepatol. 2017 Feb;32(2):427-438.
Title:	Tumor testing to identify lynch syndrome in two Australian colorectal cancer cohorts.
Author:	Buchanan, Daniel D\|Clendenning, Mark\|Rosty, Christophe\|Eriksen, Stine V\|Walsh, Michael D\|Walters, Rhiannon J\|Thibodeau, Stephen N\|Stewart, Jenna\|Preston, Susan\|Win, Aung Ko\|Flander, Louisa\|Ouakrim, Driss Ait\|Macrae, Finlay A\|Boussioutas, Alex\|Winship, Ing
PMID:	27273229

1576.
Journal:	Oncogene. 2017 Jan 19;36(3):423-428.
Title:	Inhibition of the CRAF/prohibitin interaction reverses CRAF-dependent resistance to vemurafenib.
Author:	Doudican, N A\|Orlow, S J
PMID:	27321184

1577.
Journal:	Mol Imaging Biol. 2017 Feb;19(1):109-119.
Title:	Evaluation of [(18)F]Fluorothymidine as a Biomarker for Early Therapy Response in a Mouse Model of Colorectal Cancer.
Author:	Rapic, Sara\|Vangestel, Christel\|Verhaeghe, Jeroen\|Thomae, David\|Pauwels, Patrick\|Van den Wyngaert, Tim\|Staelens, Steven\|Stroobants, Sigrid
PMID:	27324368

1578.
Journal:	Gut. 2017 Sep;66(9):1645-1656.
Title:	RNF43 germline and somatic mutation in serrated neoplasia pathway and its association with BRAF mutation.
Author:	Yan, Helen H N\|Lai, Jeffrey C W\|Ho, Siu Lun\|Leung, Wai Keung\|Law, Wai Lun\|Lee, Janet F Y\|Chan, Anthony K W\|Tsui, Wai Yin\|Chan, Annie S Y\|Lee, Bernard C H\|Yue, Sarah S K\|Man, Alice H Y\|Clevers, Hans\|Yuen, Siu Tsan\|Leung, Suet Yi
PMID:	27329244

1579.
Journal:	Clin Cancer Res. 2017 Jan 1;23(1):104-115.
Title:	BRAF V600E Mutant Colorectal Cancer Subtypes Based on Gene Expression.
Author:	Barras, David\|Missiaglia, Edoardo\|Wirapati, Pratyaksha\|Sieber, Oliver M\|Jorissen, Robert N\|Love, Chris\|Molloy, Peter L\|Jones, Ian T\|McLaughlin, Stephen\|Gibbs, Peter\|Guinney, Justin\|Simon, Iris M\|Roth, Arnaud D\|Bosman, Fred T\|Tejpar, Sabine\|Delorenzi, Maur
PMID:	27354468

1580.
Journal:	J Gastroenterol Hepatol. 2017 Feb;32(2):358-367.
Title:	Clinicopathological characteristics of serrated polyps as precursors to colorectal cancer: Current status and management.
Author:	Okamoto, Koichi\|Kitamura, Shinji\|Kimura, Tetsuo\|Nakagawa, Tadahiko\|Sogabe, Masahiro\|Miyamoto, Hiroshi\|Muguruma, Naoki\|Takayama, Tetsuji
PMID:	27376251

1581.
Journal:	Cancer Res Treat. 2017 Jan;49(1):161-167.
Title:	Paired Primary and Metastatic Tumor Analysis of Somatic Mutations in Synchronous and Metachronous Colorectal Cancer.
Author:	Kim, Kyu-Pyo\|Kim, Jeong-Eun\|Hong, Yong Sang\|Ahn, Sung-Min\|Chun, Sung Min\|Hong, Seung-Mo\|Jang, Se Jin\|Yu, Chang Sik\|Kim, Jin Cheon\|Kim, Tae Won
PMID:	27384156

1582.
Journal:	Oncogene. 2017 Feb 9;36(6):787-796.
Title:	FBW7 mutations mediate resistance of colorectal cancer to targeted therapies by blocking Mcl-1 degradation.
Author:	Tong, J\|Tan, S\|Zou, F\|Yu, J\|Zhang, L
PMID:	27399335

1583.
Journal:	Histopathology. 2017 Jan;70(2):223-231.
Title:	Micropapillary colorectal carcinoma: clinical, pathological and molecular properties, including evidence of epithelial-mesenchymal transition.
Author:	Gonzalez, Raul S\|Huh, Won Jae\|Cates, Justin M M\|Washington, Kay\|Beauchamp, R Daniel\|Coffey, Robert J\|Shi, Chanjuan
PMID:	27560620

1584.
Journal:	Int J Surg Pathol. 2017 Apr;25(2):108-117.
Title:	Mucinous and Signet Ring Cell Differentiation Affect Patterns of Metastasis in Colorectal Carcinoma and Influence Survival.
Author:	Kermanshahi, Taher Reza\|Magge, Deepa\|Choudry, Haroon\|Ramalingam, Leksmi\|Zhu, Benjamin\|Pingpank, James\|Ahrendt, Steven\|Holtzman, Matthew\|Zeh, Herbert\|Bartlett, David\|Zureikat, Amer\|Pai, Reetesh K
PMID:	27571790

1585.
Journal:	Semin Cell Dev Biol. 2017 Apr;64:107-115.
Title:	Colorectal cancer heterogeneity and targeted therapy: Clinical implications, challenges and solutions for treatment resistance.
Author:	Zhai, Zhenhua\|Yu, Xiaohui\|Yang, Bin\|Zhang, Yunjing\|Zhang, Long\|Li, Xiaoli\|Sun, Hongzhi
PMID:	27578007

1586.
Journal:	Future Oncol. 2017 Jan;13(2):135-144.
Title:	Comparison of the molecular profile of brain metastases from colorectal cancer and corresponding primary tumors.
Author:	Aprile, Giuseppe\|Casagrande, Mariaelena\|De Maglio, Giovanna\|Fontanella, Caterina\|Rihawi, Karim\|Bonotto, Marta\|Pisa, Federica E\|Tuniz, Francesco\|Pizzolitto, Stefano\|Fasola, Gianpiero
PMID:	27578453

1587.
Journal:	Gut. 2017 Dec;66(12):2132-2140.
Title:	Subclonal diversity arises early even in small colorectal tumours and contributes to differential growth fates.
Author:	Sievers, Chelsie K\|Zou, Luli S\|Pickhardt, Perry J\|Matkowskyj, Kristina A\|Albrecht, Dawn M\|Clipson, Linda\|Bacher, Jeffery W\|Pooler, B Dustin\|Moawad, Fouad J\|Cash, Brooks D\|Reichelderfer, Mark\|Vo, Tien N\|Newton, Michael A\|Larget, Bret R\|Halberg, Richard B
PMID:	27609830

1588.
Journal:	Invest New Drugs. 2017 Feb;35(1):47-58.
Title:	A phase I dose-escalation study of TAK-733, an investigational oral MEK inhibitor, in patients with advanced solid tumors.
Author:	Adjei, Alex A\|LoRusso, Patricia\|Ribas, Antoni\|Sosman, Jeffrey A\|Pavlick, Anna\|Dy, Grace K\|Zhou, Xiaofei\|Gangolli, Esha\|Kneissl, Michelle\|Faucette, Stephanie\|Neuwirth, Rachel\|Bozon, Viviana
PMID:	27650277

1589.
Journal:	J Cancer Res Clin Oncol. 2017 Jan;143(1):151-160.
Title:	Prognostic value of BRAF V600E mutation and microsatellite instability in Japanese patients with sporadic colorectal cancer.
Author:	Nakaji, Yu\|Oki, Eiji\|Nakanishi, Ryota\|Ando, Koji\|Sugiyama, Masahiko\|Nakashima, Yuichiro\|Yamashita, Nami\|Saeki, Hiroshi\|Oda, Yoshinao\|Maehara, Yoshihiko
PMID:	27672042

1590.
Journal:	Mod Pathol. 2017 Jan;30(1):113-122.
Title:	Colorectal carcinomas with submucosal invasion (pT1): analysis of histopathological and molecular factors predicting lymph node metastasis.
Author:	Pai, Reetesh K\|Cheng, Yu-Wei\|Jakubowski, Maureen A\|Shadrach, Bonnie L\|Plesec, Thomas P\|Pai, Rish K
PMID:	27713420

1591.
Journal:	Mol Imaging Biol. 2017 Jun;19(3):421-428.
Title:	Non-Invasive Glutamine PET Reflects Pharmacological Inhibition of BRAF(V600E) In Vivo.
Author:	Schulte, Michael L\|Hight, Matthew R\|Ayers, Gregory D\|Liu, Qi\|Shyr, Yu\|Washington, M Kay\|Manning, H Charles
PMID:	27770401

1592.
Journal:	J Natl Cancer Inst. 2016 Oct 22;109(2). pii: djw209.
Title:	Efficacy of NEDD8 Pathway Inhibition in Preclinical Models of Poorly Differentiated, Clinically Aggressive Colorectal Cancer.
Author:	Picco, Gabriele\|Petti, Consalvo\|Sassi, Francesco\|Grillone, Katia\|Migliardi, Giorgia\|Rossi, Teresa\|Isella, Claudio\|Di Nicolantonio, Federica\|Sarotto, Ivana\|Sapino, Anna\|Bardelli, Alberto\|Trusolino, Livio\|Bertotti, Andrea\|Medico, Enzo
PMID:	27771609

1593.
Journal:	Mod Pathol. 2017 Feb;30(2):278-285.
Title:	Clinicopathologic profile, immunophenotype, and genotype of CD274 (PD-L1)-positive colorectal carcinomas.
Author:	Inaguma, Shingo\|Lasota, Jerzy\|Wang, Zengfeng\|Felisiak-Golabek, Anna\|Ikeda, Hiroshi\|Miettinen, Markku
PMID:	27813511

1594.
Journal:	Clin Cancer Res. 2017 Jun 1;23(11):2742-2749.
Title:	BRAF and NRAS Locus-Specific Variants Have Different Outcomes on Survival to Colorectal Cancer.
Author:	Summers, Matthew G\|Smith, Christopher G\|Maughan, Timothy S\|Kaplan, Richard\|Escott-Price, Valentina\|Cheadle, Jeremy P
PMID:	27815357

1595.
Journal:	Oncologist. 2017 Jan;22(1):107-114.
Title:	A Study of Thymidylate Synthase Expression as a Biomarker for Resectable Colon Cancer: Alliance (Cancer and Leukemia Group B) 9581 and 89803.
Author:	Niedzwiecki, Donna\|Hasson, Rian M\|Lenz, Heinz-Josef\|Ye, Cynthia\|Redston, Mark\|Ogino, Shuji\|Fuchs, Charles S\|Compton, Carolyn C\|Mayer, Robert J\|Goldberg, Richard M\|Colacchio, Thomas A\|Saltz, Leonard B\|Warren, Robert S\|Bertagnolli, Monica M
PMID:	27821793

1596.
Journal:	Eur J Surg Oncol. 2017 Feb;43(2):311-321.
Title:	Associations of defect mismatch repair genes with prognosis and heredity in sporadic colorectal cancer.
Author:	Ghanipour, L\|Jirstrom, K\|Sundstrom, M\|Glimelius, B\|Birgisson, H
PMID:	27836416

1597.
Journal:	Int J Cancer. 2017 Feb 15;140(4):922-929.
Title:	EGFR gene copy number predicts response to anti-EGFR treatment in RAS wild type and RAS/BRAF/PIK3CA wild type metastatic colorectal cancer.
Author:	Algars, Annika\|Sundstrom, Jari\|Lintunen, Minnamaija\|Jokilehto, Terhi\|Kytola, Soili\|Kaare, Milja\|Vainionpaa, Reetta\|Orpana, Arto\|Osterlund, Pia\|Ristimaki, Ari\|Carpen, Olli\|Ristamaki, Raija
PMID:	27879995

1598.
Journal:	Oncotarget. 2017 Jan 3;8(1):444-457.
Title:	Evolutionary biologic changes of gut microbiota in an 'adenoma-carcinoma sequence' mouse colorectal cancer model induced by 1, 2-Dimethylhydrazine.
Author:	Sun, Teng\|Liu, Shanglong\|Zhou, Yanbing\|Yao, Zengwu\|Zhang, Dongfeng\|Cao, Shougen\|Wei, Zhiliang\|Tan, Bin\|Li, Yi\|Lian, Zheng\|Wang, Song
PMID:	27880935

1599.
Journal:	Gut Liver. 2017 Jan 15;11(1):38-46.
Title:	CpG Island Methylator Phenotype-High Colorectal Cancers and Their Prognostic Implications and Relationships with the Serrated Neoplasia Pathway.
Author:	Rhee, Ye-Young\|Kim, Kyung-Ju\|Kang, Gyeong Hoon
PMID:	27885175

1600.
Journal:	J Korean Med Sci. 2017 Jan;32(1):38-46.
Title:	BRAF-Mutated Colorectal Cancer Exhibits Distinct Clinicopathological Features from Wild-Type BRAF-Expressing Cancer Independent of the Microsatellite Instability Status.
Author:	Jang, Min Hye\|Kim, Sehun\|Hwang, Dae Yong\|Kim, Wook Youn\|Lim, So Dug\|Kim, Wan Seop\|Hwang, Tea Sook\|Han, Hye Seung
PMID:	27914130

1601.
Journal:	Oncology. 2017;92(2):75-86.
Title:	Clinicopathological Features and Predictive Factors for Colorectal Cancer Outcome in the Kingdom of Saudi Arabia.
Author:	Aldiab, Abdurrahman\|Al Khayal, Khayal A\|Al Obaid, Omar A\|Alsheikh, Ahmed\|Alsaleh, Khalid\|Shahid, Mohamed\|Alkharji, Hana
PMID:	27915339

1602.
Journal:	Jpn J Clin Oncol. 2017 Feb 9;47(2):108-117.
Title:	Prevalence of Lynch syndrome and Lynch-like syndrome among patients with colorectal cancer in a Japanese hospital-based population.
Author:	Chika, Noriyasu\|Eguchi, Hidetaka\|Kumamoto, Kensuke\|Suzuki, Okihide\|Ishibashi, Keiichiro\|Tachikawa, Tetsuhiko\|Akagi, Kiwamu\|Tamaru, Jun-Ichi\|Okazaki, Yasushi\|Ishida, Hideyuki
PMID:	27920101

1603.
Journal:	J Mol Model. 2017 Jan;23(1):1.
Title:	Chemotherapeutic drug selectivity between wild-type and mutant BRaf kinases in colon cancer.
Author:	Zhang, Jianchun\|Ji, Tao
PMID:	27921184

1604.
Journal:	Int J Cancer. 2017 Apr 1;140(7):1485-1493.
Title:	Lifetime alcohol intake is associated with an increased risk of KRAS+ and BRAF-/KRAS- but not BRAF+ colorectal cancer.
Author:	Jayasekara, Harindra\|MacInnis, Robert J\|Williamson, Elizabeth J\|Hodge, Allison M\|Clendenning, Mark\|Rosty, Christophe\|Walters, Rhiannon\|Room, Robin\|Southey, Melissa C\|Jenkins, Mark A\|Milne, Roger L\|Hopper, John L\|Giles, Graham G\|Buchanan, Daniel D\|English,
PMID:	27943267

1605.
Journal:	Biochem Biophys Res Commun. 2017 Jan 22;482(4):1491-1497.
Title:	BRAF-mutated cells activate GCN2-mediated integrated stress response as a cytoprotective mechanism in response to vemurafenib.
Author:	Nagasawa, Ikuko\|Kunimasa, Kazuhiro\|Tsukahara, Satomi\|Tomida, Akihiro
PMID:	27965097

1606.
Journal:	Cancer Epidemiol Biomarkers Prev. 2017 Apr;26(4):622-631.
Title:	Cytotoxic T Cells and Granzyme B Associated with Improved Colorectal Cancer Survival in a Prospective Cohort of Older Women.
Author:	Prizment, Anna E\|Vierkant, Robert A\|Smyrk, Thomas C\|Tillmans, Lori S\|Nelson, Heather H\|Lynch, Charles F\|Pengo, Thomas\|Thibodeau, Stephen N\|Church, Timothy R\|Cerhan, James R\|Anderson, Kristin E\|Limburg, Paul J
PMID:	27979806

1607.
Journal:	Mod Pathol. 2017 Apr;30(4):599-609.
Title:	Morphological characterization of colorectal cancers in The Cancer Genome Atlas reveals distinct morphology-molecular associations: clinical and biological implications.
Author:	Shia, Jinru\|Schultz, Nikolaus\|Kuk, Deborah\|Vakiani, Efsevia\|Middha, Sumit\|Segal, Neil H\|Hechtman, Jaclyn F\|Berger, Michael F\|Stadler, Zsofia K\|Weiser, Martin R\|Wolchok, Jedd D\|Boland, C Richard\|Gonen, Mithat\|Klimstra, David S
PMID:	27982025

1608.
Journal:	Ann Oncol. 2017 Mar 1;28(3):562-568.
Title:	Investigating the poor outcomes of BRAF-mutant advanced colorectal cancer: analysis from 2530 patients in randomised clinical trials.
Author:	Seligmann, J F\|Fisher, D\|Smith, C G\|Richman, S D\|Elliott, F\|Brown, S\|Adams, R\|Maughan, T\|Quirke, P\|Cheadle, J\|Seymour, M\|Middleton, G
PMID:	27993800

1609.
Journal:	Oncotarget. 2017 Feb 7;8(6):9251-9266.
Title:	LY3009120, a panRAF inhibitor, has significant anti-tumor activity in BRAF and KRAS mutant preclinical models of colorectal cancer.
Author:	Vakana, Eliza\|Pratt, Susan\|Blosser, Wayne\|Dowless, Michele\|Simpson, Nicholas\|Yuan, Xiu-Juan\|Jaken, Susan\|Manro, Jason\|Stephens, Jennifer\|Zhang, Youyan\|Huber, Lysiane\|Peng, Sheng-Bin\|Stancato, Louis F
PMID:	27999210

1610.
Journal:	Oncol Rep. 2017 Feb;37(2):785-792.
Title:	High concordance rate of KRAS/BRAF mutations and MSI-H between primary colorectal cancer and corresponding metastases.
Author:	Fujiyoshi, Kenji\|Yamamoto, Gou\|Takahashi, Akemi\|Arai, Yoshiko\|Yamada, Mina\|Kakuta, Miho\|Yamaguchi, Kensei\|Akagi, Yoshito\|Nishimura, Yoji\|Sakamoto, Hirohiko\|Akagi, Kiwamu
PMID:	28000889

1611.
Journal:	Oncotarget. 2017 Jan 31;8(5):7852-7866.
Title:	Targeted exome sequencing reveals distinct pathogenic variants in Iranians with colorectal cancer.
Author:	Ashktorab, Hassan\|Mokarram, Pooneh\|Azimi, Hamed\|Olumi, Hasti\|Varma, Sudhir\|Nickerson, Michael L\|Brim, Hassan
PMID:	28002797

1612.
Journal:	Oncotarget. 2017 Jan 17;8(3):5003-5015.
Title:	Concomitant inhibition of receptor tyrosine kinases and downstream AKT synergistically inhibited growth of KRAS/BRAF mutant colorectal cancer cells.
Author:	Song, Qiaoling\|Sun, Xiaoxiao\|Guo, Hui\|Yu, Qiang
PMID:	28002807

1613.
Journal:	JAMA Oncol. 2017 Apr 1;3(4):472-480.
Title:	Association of DNA Mismatch Repair and Mutations in BRAF and KRAS With Survival After Recurrence in Stage III Colon Cancers : A Secondary Analysis of 2 Randomized Clinical Trials.
Author:	Sinicrope, Frank A\|Shi, Qian\|Allegra, Carmen J\|Smyrk, Thomas C\|Thibodeau, Stephen N\|Goldberg, Richard M\|Meyers, Jeffrey P\|Pogue-Geile, Kay L\|Yothers, Greg\|Sargent, Daniel J\|Alberts, Steven R
PMID:	28006055

1614.
Journal:	Crit Rev Oncol Hematol. 2017 Jan;109:9-19.
Title:	Clinical relevance of colorectal cancer molecular subtypes.
Author:	Rodriguez-Salas, Nuria\|Dominguez, Gema\|Barderas, Rodrigo\|Mendiola, Marta\|Garcia-Albeniz, Xabier\|Maurel, Juan\|Batlle, Jaime Feliu
PMID:	28010901

1615.
Journal:	Anticancer Res. 2017 Jan;37(1):239-247.
Title:	Metastatic Pattern of Stage IV Colorectal Cancer with High-Frequency Microsatellite Instability as a Prognostic Factor.
Author:	Fujiyoshi, Kenji\|Yamamoto, Gou\|Takenoya, Takashi\|Takahashi, Akemi\|Arai, Yoshiko\|Yamada, Mina\|Kakuta, Miho\|Yamaguchi, Kensei\|Akagi, Yoshito\|Nishimura, Yoji\|Sakamoto, Hirohiko\|Akagi, Kiwamu
PMID:	28011498

1616.
Journal:	Gastroenterology. 2017 Apr;152(5):1002-1013.e9.
Title:	Detection of Sessile Serrated Adenomas in the Proximal Colon Using Wide-Field Fluorescence Endoscopy.
Author:	Joshi, Bishnu P\|Dai, Zhenzhen\|Gao, Zhenghong\|Lee, Jeong Hoon\|Ghimire, Navin\|Chen, Jing\|Prabhu, Anoop\|Wamsteker, Erik J\|Kwon, Richard S\|Elta, Grace H\|Stoffel, Elena M\|Pant, Asha\|Kaltenbach, Tonya\|Soetikno, Roy M\|Appelman, Henry D\|Kuick, Rork\|Turgeon, D Kim
PMID:	28012848

1617.
Journal:	Hum Pathol. 2017 Apr;62:91-98.
Title:	Analysis of KRAS, NRAS, PIK3CA, and BRAF mutational profile in poorly differentiated clusters of KRAS-mutated colon cancer.
Author:	Reggiani Bonetti, Luca\|Barresi, Valeria\|Bettelli, Stefania\|Caprera, Cecilia\|Manfredini, Samantha\|Maiorana, Antonio
PMID:	28025078

1618.
Journal:	Pathol Oncol Res. 2017 Jul;23(3):673-677.
Title:	EGFR Gene Amplification and KRAS Mutation Predict Response to Combination Targeted Therapy in Metastatic Colorectal Cancer.
Author:	Khan, Sajid A\|Zeng, Zhaoshi\|Shia, Jinru\|Paty, Philip B
PMID:	28025786

1619.
Journal:	Ann Oncol. 2017 Apr 1;28(4):824-830.
Title:	Adjuvant FOLFOX +/- cetuximab in full RAS and BRAF wildtype stage III colon cancer patients.
Author:	Taieb, J\|Balogoun, R\|Le Malicot, K\|Tabernero, J\|Mini, E\|Folprecht, G\|Van Laethem, J-L\|Emile, J-F\|Mulot, C\|Fratte, S\|Levache, C-B\|Saban-Roche, L\|Thaler, J\|Petersen, L N\|Bridgewater, J\|Perkins, G\|Lepage, C\|Van Cutsem, E\|Zaanan, A\|Laurent-Puig, P
PMID:	28031175

1620.
Journal:	J Natl Cancer Inst. 2016 Dec 31;109(5). pii: 2760215.
Title:	Prognostic Value of BRAF and KRAS Mutations in MSI and MSS Stage III Colon Cancer.
Author:	Taieb, Julien\|Le Malicot, Karine\|Shi, Qian\|Penault-Llorca, Frederique\|Bouche, Olivier\|Tabernero, Josep\|Mini, Enrico\|Goldberg, Richard M\|Folprecht, Gunnar\|Luc Van Laethem, Jean\|Sargent, Daniel J\|Alberts, Steven R\|Emile, Jean Francois\|Laurent Puig, Pierre\|S
PMID:	28040692

1621.
Journal:	J Natl Compr Canc Netw. 2017 Jan;15(1):3-8.
Title:	Prolonged Response to HER2-Directed Therapy in a Patient With HER2-Amplified, Rapidly Progressive Metastatic Colorectal Cancer.
Author:	Parikh, Aparna\|Atreya, Chloe\|Korn, W Michael\|Venook, Alan P
PMID:	28040715

1622.
Journal:	Mod Pathol. 2017 Mar;30(3):440-447.
Title:	A tailored approach to BRAF and MLH1 methylation testing in a universal screening program for Lynch syndrome.
Author:	Adar, Tomer\|Rodgers, Linda H\|Shannon, Kristen M\|Yoshida, Makoto\|Ma, Tianle\|Mattia, Anthony\|Lauwers, Gregory Y\|Iafrate, Anthony J\|Chung, Daniel C
PMID:	28059100

1623.
Journal:	Clin Colorectal Cancer. 2017 Sep;16(3):228-239.
Title:	Response to Chemotherapy and Prognosis in Metastatic Colorectal Cancer With DNA Deficient Mismatch Repair.
Author:	Alex, Alexandra Khichfy\|Siqueira, Sheila\|Coudry, Renata\|Santos, Juliana\|Alves, Michel\|Hoff, Paulo M\|Riechelmann, Rachel P
PMID:	28063788

1624.
Journal:	Future Oncol. 2017 Apr;13(10):919-934.
Title:	Translating genomic profiling to gastrointestinal cancer treatment.
Author:	Harada, Kazuto\|Mizrak Kaya, Dilsa\|Shimodaira, Yusuke\|Song, Shumei\|Baba, Hideo\|Ajani, Jaffer A
PMID:	28067073

1625.
Journal:	BMC Cancer. 2017 Jan 9;17(1):38.
Title:	Retrospective study of RAS/PIK3CA/BRAF tumor mutations as predictors of response to first-line chemotherapy with bevacizumab in metastatic colorectal cancer patients.
Author:	Nakayama, Izuma\|Shinozaki, Eiji\|Matsushima, Tomohiro\|Wakatsuki, Takeru\|Ogura, Mariko\|Ichimura, Takashi\|Ozaka, Masato\|Takahari, Daisuke\|Suenaga, Mitsukuni\|Chin, Keisho\|Mizunuma, Nobuyuki\|Yamaguchi, Kensei
PMID:	28068936

1626.
Journal:	Elife. 2017 Jan 10;6.
Title:	BRAF(V600E) cooperates with CDX2 inactivation to promote serrated colorectal tumorigenesis.
Author:	Sakamoto, Naoya\|Feng, Ying\|Stolfi, Carmine\|Kurosu, Yuki\|Green, Maranne\|Lin, Jeffry\|Green, Megan E\|Sentani, Kazuhiro\|Yasui, Wataru\|McMahon, Martin\|Hardiman, Karin M\|Spence, Jason R\|Horita, Nobukatsu\|Greenson, Joel K\|Kuick, Rork\|Cho, Kathleen R\|Fearon, Eric
PMID:	28072391

1627.
Journal:	Med Oncol. 2017 Feb;34(2):26.
Title:	KRAS, NRAS and BRAF mutations in colorectal cancer and melanoma.
Author:	Cicenas, Jonas\|Tamosaitis, Linas\|Kvederaviciute, Kotryna\|Tarvydas, Ricardas\|Staniute, Gintare\|Kalyan, Karthik\|Meskinyte-Kausiliene, Edita\|Stankevicius, Vaidotas\|Valius, Mindaugas
PMID:	28074351

1628.
Journal:	Cancer Sci. 2017 Mar;108(3):427-434.
Title:	Molecular subtypes of colorectal cancers determined by PCR-based analysis.
Author:	Sugai, Tamotsu\|Eizuka, Makoto\|Takahashi, Yayoi\|Fukagawa, Tomoyuki\|Habano, Wataru\|Yamamoto, Eiichiro\|Akasaka, Risaburo\|Otuska, Kouki\|Matsumoto, Takayuki\|Suzuki, Hiromu
PMID:	28083970

1629.
Journal:	Bull Exp Biol Med. 2017 Jan;162(3):375-378.
Title:	Detection of Rare Mutations by Routine Analysis of KRAS, NRAS, and BRAF Oncogenes.
Author:	Mikhailenko, D S\|Efremov, G D\|Safronova, N Yu\|Strelnikov, V V\|Alekseev, B Ya
PMID:	28091917

1630.
Journal:	World J Surg. 2017 May;41(5):1375-1383.
Title:	Genetic and Epigenetic Intra-tumour Heterogeneity in Colorectal Cancer.
Author:	Jones, Huw Geraint\|Jenkins, Gareth\|Williams, Namor\|Griffiths, Paul\|Chambers, Phil\|Beynon, John\|Harris, Dean
PMID:	28097409

1631.
Journal:	Zhonghua Wei Chang Wai Ke Za Zhi. 2017 Jan 25;20(1):24-27.
Title:	[Improvement of prognostic and predictive network of colorectal cancer based upon the 8th edition of AJCC colorectal cancer staging system].
Author:	Yao, Hongwei\|Wu, Hongwei\|Liu, Yinhua
PMID:	28105615

1632.
Journal:	Int J Mol Sci. 2017 Jan 19;18(1). pii: ijms18010197.
Title:	Colorectal Carcinoma: A General Overview and Future Perspectives in Colorectal Cancer.
Author:	Marmol, Ines\|Sanchez-de-Diego, Cristina\|Pradilla Dieste, Alberto\|Cerrada, Elena\|Rodriguez Yoldi, Maria Jesus
PMID:	28106826

1633.
Journal:	Am J Gastroenterol. 2017 Mar;112(3):493-501.
Title:	A Prospective Study of Smoking and Risk of Synchronous Colorectal Cancers.
Author:	Drew, David A\|Nishihara, Reiko\|Lochhead, Paul\|Kuchiba, Aya\|Qian, Zhi Rong\|Mima, Kosuke\|Nosho, Katsuhiko\|Wu, Kana\|Wang, Molin\|Giovannucci, Edward\|Fuchs, Charles S\|Chan, Andrew T\|Ogino, Shuji
PMID:	28117362

1634.
Journal:	PLoS One. 2017 Jan 26;12(1):e0170775.
Title:	The Influence of BRAF and KRAS Mutation Status on the Association between Aspirin Use and Survival after Colon Cancer Diagnosis.
Author:	Frouws, Martine A\|Reimers, Marlies S\|Swets, Marloes\|Bastiaannet, Esther\|Prinse, Bianca\|van Eijk, Ronald\|Lemmens, Valery E P P\|van Herk-Sukel, Myrthe P P\|van Wezel, Tom\|Kuppen, Peter J K\|Morreau, Hans\|van de Velde, Cornelis J H\|Liefers, Gerrit-Jan
PMID:	28125730

1635.
Journal:	Oncotarget. 2017 Mar 14;8(11):17810-17818.
Title:	EZH2 expression is a prognostic biomarker in patients with colorectal cancer treated with anti-EGFR therapeutics.
Author:	Yamamoto, Itaru\|Nosho, Katsuhiko\|Kanno, Shinichi\|Igarashi, Hisayoshi\|Kurihara, Hiroyoshi\|Ishigami, Keisuke\|Ishiguro, Kazuya\|Mitsuhashi, Kei\|Maruyama, Reo\|Koide, Hideyuki\|Okuda, Hiroyuki\|Hasegawa, Tadashi\|Sukawa, Yasutaka\|Okita, Kenji\|Takemasa, Ichiro\|Yama
PMID:	28147317

1636.
Journal:	Br J Cancer. 2017 Feb 28;116(5):575-583.
Title:	A phase 1 dose-escalation and expansion study of binimetinib (MEK162), a potent and selective oral MEK1/2 inhibitor.
Author:	Bendell, Johanna C\|Javle, Milind\|Bekaii-Saab, Tanios S\|Finn, Richard S\|Wainberg, Zev A\|Laheru, Daniel A\|Weekes, Colin D\|Tan, Benjamin R\|Khan, Gazala N\|Zalupski, Mark M\|Infante, Jeffrey R\|Jones, Suzanne\|Papadopoulos, Kyriakos P\|Tolcher, Anthony W\|Chavira,
PMID:	28152546

1637.
Journal:	Cancer Discov. 2017 Mar;7(3):242.
Title:	Drug Combo Beats Vemurafenib Alone for Colorectal Cancer.
Author:
PMID:	28153858

1638.
Journal:	Br J Cancer. 2017 Mar 14;116(6):802-810.
Title:	Development of a gene panel for next-generation sequencing of clinically relevant mutations in cell-free DNA from cancer patients.
Author:	Malapelle, Umberto\|Mayo de-Las-Casas, Clara\|Rocco, Danilo\|Garzon, Monica\|Pisapia, Pasquale\|Jordana-Ariza, Nuria\|Russo, Maria\|Sgariglia, Roberta\|De Luca, Caterina\|Pepe, Francesco\|Martinez-Bueno, Alejandro\|Morales-Espinosa, Daniela\|Gonzalez-Cao, Maria\|Karac
PMID:	28170370

1639.
Journal:	Mol Oncol. 2017 May;11(5):470-490.
Title:	Enhanced dependency of KRAS-mutant colorectal cancer cells on RAD51-dependent homologous recombination repair identified from genetic interactions in Saccharomyces cerevisiae.
Author:	Kalimutho, Murugan\|Bain, Amanda L\|Mukherjee, Bipasha\|Nag, Purba\|Nanayakkara, Devathri M\|Harten, Sarah K\|Harris, Janelle L\|Subramanian, Goutham N\|Sinha, Debottam\|Shirasawa, Senji\|Srihari, Sriganesh\|Burma, Sandeep\|Khanna, Kum Kum
PMID:	28173629

1640.
Journal:	Anticancer Res. 2017 Feb;37(2):651-657.
Title:	Comparative Study of Mutations in Single Nucleotide Polymorphism Loci of KRAS and BRAF Genes in Patients Who Underwent Screening Colonoscopy, With and Without Premalignant Intestinal Polyps.
Author:	Galanopoulos, Michail\|Papanikolaou, Ioannis S\|Zografos, Eleni\|Viazis, Nikos\|Papatheodoridis, George\|Karamanolis, Dimitrios\|Marinos, Evangelos\|Mantzaris, Gerassimos J\|Gazouli, Maria
PMID:	28179313

1641.
Journal:	Mol Oncol. 2017 Jun;11(6):599-611.
Title:	Heat-shock protein 27 (HSP27, HSPB1) is synthetic lethal to cells with oncogenic activation of MET, EGFR and BRAF.
Author:	Konda, John D\|Olivero, Martina\|Musiani, Daniele\|Lamba, Simona\|Di Renzo, Maria F
PMID:	28182330

1642.
Journal:	Mol Cancer Res. 2017 Jun;15(6):708-713.
Title:	Chromosome 20q Amplification Defines a Subtype of Microsatellite Stable, Left-Sided Colon Cancers with Wild-type RAS/RAF and Better Overall Survival.
Author:	Ptashkin, Ryan N\|Pagan, Carlos\|Yaeger, Rona\|Middha, Sumit\|Shia, Jinru\|O'Rourke, Kevin P\|Berger, Michael F\|Wang, Lu\|Cimera, Robert\|Wang, Jiajing\|Klimstra, David S\|Saltz, Leonard\|Ladanyi, Marc\|Zehir, Ahmet\|Hechtman, Jaclyn F
PMID:	28184012

1643.
Journal:	Eur J Cardiothorac Surg. 2017 Feb 1;51(2):255-262.
Title:	Perioperative bevacizumab improves survival following lung metastasectomy for colorectal cancer in patients harbouring v-Ki-ras2 Kirsten rat sarcoma viral oncogene homologue exon 2 codon 12 mutationsdagger.
Author:	Renaud, Stephane\|Schaeffer, Mickael\|Falcoz, Pierre-Emmanuel\|Seitlinger, Joseph\|Romain, Benoit\|Voegeli, Anne-Claire\|Legrain, Michele\|Reeb, Jeremie\|Santelmo, Nicola\|Rohr, Serge\|Brigand, Cecile\|Olland, Anne\|Guenot, Dominique\|Massard, Gilbert
PMID:	28186237

1644.
Journal:	Mol Cell Proteomics. 2017 Apr;16(4):663-679.
Title:	Time-resolved Phosphoproteome Analysis of Paradoxical RAF Activation Reveals Novel Targets of ERK.
Author:	Kubiniok, Peter\|Lavoie, Hugo\|Therrien, Marc\|Thibault, Pierre
PMID:	28188228

1645.
Journal:	Hum Pathol. 2017 Jul;65:21-30.
Title:	KRAS and PIK3CA mutations in colorectal adenocarcinomas correlate with aggressive histological features and behavior.
Author:	Jang, Sejin\|Hong, Mineui\|Shin, Mi Kyung\|Kim, Byung Chun\|Shin, Hyung-Sik\|Yu, Eunsil\|Hong, Seung-Mo\|Kim, Jihun\|Chun, Sung-Min\|Kim, Tae-Im\|Choi, Kyung-Chan\|Ko, Young Woong\|Kim, Jeong Won
PMID:	28188750

1646.
Journal:	Curr Treat Options Oncol. 2017 Feb;18(2):9.
Title:	BRAF-Mutated Colorectal Cancer: What Is the Optimal Strategy for Treatment?
Author:	Cohen, Romain\|Cervera, Pascale\|Svrcek, Magali\|Pellat, Anna\|Dreyer, Chantal\|de Gramont, Aimery\|Andre, Thierry
PMID:	28214977

1647.
Journal:	Clin Colorectal Cancer. 2017 Sep;16(3):e153-e163.
Title:	Effect of KRAS and BRAF Mutations on Survival of Metastatic Colorectal Cancer After Liver Resection: A Systematic Review and Meta-Analysis.
Author:	Tosi, Federica\|Magni, Elena\|Amatu, Alessio\|Mauri, Gianluca\|Bencardino, Katia\|Truini, Mauro\|Veronese, Silvio\|De Carlis, Luciano\|Ferrari, Giovanni\|Nichelatti, Michele\|Sartore-Bianchi, Andrea\|Siena, Salvatore
PMID:	28216246

1648.
Journal:	Mol Carcinog. 2017 Jul;56(7):1743-1752.
Title:	Epigenetic silencing of diacylglycerol kinase gamma in colorectal cancer.
Author:	Kai, Masahiro\|Yamamoto, Eiichiro\|Sato, Akiko\|Yamano, Hiro-O\|Niinuma, Takeshi\|Kitajima, Hiroshi\|Harada, Taku\|Aoki, Hironori\|Maruyama, Reo\|Toyota, Mutsumi\|Hatahira, Tomo\|Nakase, Hiroshi\|Sugai, Tamotsu\|Yamashita, Toshiharu\|Toyota, Minoru\|Suzuki, Hiromu
PMID:	28218473

1649.
Journal:	J Pathol Transl Med. 2017 Mar;51(2):103-121.
Title:	Molecular Testing for Gastrointestinal Cancer.
Author:	Lee, Hye Seung\|Kim, Woo Ho\|Kwak, Yoonjin\|Koh, Jiwon\|Bae, Jeong Mo\|Kim, Kyoung-Mee\|Chang, Mee Soo\|Han, Hye Seung\|Kim, Joon Mee\|Kim, Hwal Woong\|Chang, Hee Kyung\|Choi, Young Hee\|Park, Ji Y\|Gu, Mi Jin\|Lhee, Min Jin\|Kim, Jung Yeon\|Kim, Hee Sung\|Cho, Mee-Yon
PMID:	28219002

1650.
Journal:	Front Immunol. 2017 Feb 6;8:87.
Title:	In Vivo Efficacy of Umbilical Cord Blood Stem Cell-Derived NK Cells in the Treatment of Metastatic Colorectal Cancer.
Author:	Veluchamy, John P\|Lopez-Lastra, Silvia\|Spanholtz, Jan\|Bohme, Fenna\|Kok, Nina\|Heideman, Danielle A M\|Verheul, Henk M W\|Di Santo, James P\|de Gruijl, Tanja D\|van der Vliet, Hans J
PMID:	28220124

1651.
Journal:	Tumour Biol. 2017 Feb;39(2):1010428317692265.
Title:	Prevalence and coexistence of KRAS, BRAF, PIK3CA, NRAS, TP53, and APC mutations in Indian colorectal cancer patients: Next-generation sequencing-based cohort study.
Author:	Jauhri, Mayank\|Bhatnagar, Akanksha\|Gupta, Satish\|Bp, Manasa\|Minhas, Sachin\|Shokeen, Yogender\|Aggarwal, Shyam
PMID:	28222664

1652.
Journal:	J Cancer. 2017 Jan 12;8(2):162-173.
Title:	Construction of a multiplex mutation hot spot PCR panel: the first step towards colorectal cancer genotyping on the GS Junior platform.
Author:	Peterfia, Balint\|Kalmar, Alexandra\|Patai, Arpad V\|Csabai, Istvan\|Bodor, Andras\|Micsik, Tamas\|Wichmann, Barnabas\|Egedi, Krisztina\|Hollosi, Peter\|Kovalszky, Ilona\|Tulassay, Zsolt\|Molnar, Bela
PMID:	28243320

1653.
Journal:	Orv Hetil. 2017 Mar;158(9):340-344.
Title:	[Does the sidedness determine the first line treatment of irresectable metastatic colorectal cancer?]
Author:	Kullmann, Tamas\|Sipocz, Istvan\|Pinter, Tamas
PMID:	28245681

1654.
Journal:	Gastroenterology. 2017 Jun;152(8):1944-1953.e1.
Title:	Dietary Patterns and Risk of Colorectal Cancer: Analysis by Tumor Location and Molecular Subtypes.
Author:	Mehta, Raaj S\|Song, Mingyang\|Nishihara, Reiko\|Drew, David A\|Wu, Kana\|Qian, Zhi Rong\|Fung, Teresa T\|Hamada, Tsuyoshi\|Masugi, Yohei\|da Silva, Annacarolina\|Shi, Yan\|Li, Wanwan\|Gu, Mancang\|Willett, Walter C\|Fuchs, Charles S\|Giovannucci, Edward L\|Ogino, Shuji\|
PMID:	28249812

1655.
Journal:	Anticancer Drugs. 2017 Jun;28(5):546-550.
Title:	Derived neutrophil to lymphocyte ratio as a prognostic factor in patients with advanced colorectal cancer according to RAS and BRAF status: a post-hoc analysis of the MRC COIN study.
Author:	Wood, Georgina\|Grenader, Tal\|Nash, Stephen\|Adams, Richard\|Kaplan, Richard\|Fisher, David\|Maughan, Tim\|Bridgewater, John
PMID:	28252533

1656.
Journal:	PLoS One. 2017 Mar 7;12(3):e0173345.
Title:	Association of SMAD4 mutation with patient demographics, tumor characteristics, and clinical outcomes in colorectal cancer.
Author:	Mehrvarz Sarshekeh, Amir\|Advani, Shailesh\|Overman, Michael J\|Manyam, Ganiraju\|Kee, Bryan K\|Fogelman, David R\|Dasari, Arvind\|Raghav, Kanwal\|Vilar, Eduardo\|Manuel, Shanequa\|Shureiqi, Imad\|Wolff, Robert A\|Patel, Keyur P\|Luthra, Raja\|Shaw, Kenna\|Eng, Cathy\|Ma
PMID:	28267766

1657.
Journal:	Int J Cancer. 2017 Jun 15;140(12):2648-2656.
Title:	Dietary glycemic and insulin scores and colorectal cancer survival by tumor molecular biomarkers.
Author:	Keum, NaNa\|Yuan, Chen\|Nishihara, Reiko\|Zoltick, Emilie\|Hamada, Tsuyoshi\|Martinez Fernandez, Alejandro\|Zhang, Xuehong\|Hanyuda, Akiko\|Liu, Li\|Kosumi, Keisuke\|Nowak, Jonathan A\|Jhun, Iny\|Soong, T Rinda\|Morikawa, Teppei\|Tabung, Fred K\|Qian, Zhi Rong\|Fuchs, Ch
PMID:	28268248

1658.
Journal:	J Natl Compr Canc Netw. 2017 Mar;15(3):370-398.
Title:	Colon Cancer, Version 1.2017, NCCN Clinical Practice Guidelines in Oncology.
Author:	Benson, Al B 3rd\|Venook, Alan P\|Cederquist, Lynette\|Chan, Emily\|Chen, Yi-Jen\|Cooper, Harry S\|Deming, Dustin\|Engstrom, Paul F\|Enzinger, Peter C\|Fichera, Alessandro\|Grem, Jean L\|Grothey, Axel\|Hochster, Howard S\|Hoffe, Sarah\|Hunt, Steven\|Kamel, Ahmed\|Kirilcu
PMID:	28275037

1659.
Journal:	J Natl Compr Canc Netw. 2017 Mar;15(3):411-419.
Title:	Right Versus Left Colon Cancer Biology: Integrating the Consensus Molecular Subtypes.
Author:	Lee, Michael S\|Menter, David G\|Kopetz, Scott
PMID:	28275039

1660.
Journal:	Br J Cancer. 2017 Apr 11;116(8):1012-1020.
Title:	Distinct clinical outcomes of two CIMP-positive colorectal cancer subtypes based on a revised CIMP classification system.
Author:	Bae, Jeong Mo\|Kim, Jung Ho\|Kwak, Yoonjin\|Lee, Dae-Won\|Cha, Yongjun\|Wen, Xianyu\|Lee, Tae Hun\|Cho, Nam-Yun\|Jeong, Seung-Yong\|Park, Kyu Joo\|Han, Sae Won\|Lee, Hye Seung\|Kim, Tae-You\|Kang, Gyeong Hoon
PMID:	28278514

1661.
Journal:	J Gastrointest Oncol. 2017 Feb;8(1):1-11.
Title:	Family history of colorectal cancer and its impact on survival in patients with resected stage III colon cancer: results from NCCTG Trial N0147 (Alliance).
Author:	Jansson-Knodell, Claire L\|Foster, Nathan R\|Sargent, Daniel J\|Limburg, Paul J\|Thibodeau, Stephen N\|Smyrk, Thomas C\|Sinicrope, Frank A\|Jahagirdar, Balkrishna\|Goldberg, Richard M\|Alberts, Steven R
PMID:	28280603

1662.
Journal:	J Gastrointest Oncol. 2017 Feb;8(1):109-126.
Title:	Differences in symptom occurrence, severity, and distress ratings between patients with gastrointestinal cancers who received chemotherapy alone or chemotherapy with targeted therapy.
Author:	Tantoy, Ilufredo Y\|Dhruva, Anand\|Cataldo, Janine\|Venook, Alan\|Cooper, Bruce A\|Paul, Steven M\|Levine, Jon D\|Conley, Yvette P\|Cartwright, Frances\|Lee, Kathryn\|Wright, Fay\|Miaskowski, Christine
PMID:	28280616

1663.
Journal:	J Gastrointest Oncol. 2017 Feb;8(1):164-172.
Title:	Potential actionable targets in appendiceal cancer detected by immunohistochemistry, fluorescent in situ hybridization, and mutational analysis.
Author:	Borazanci, Erkut\|Millis, Sherri Z\|Kimbrough, Jeffery\|Doll, Nancy\|Von Hoff, Daniel\|Ramanathan, Ramesh K
PMID:	28280620

1664.
Journal:	J Gastrointest Oncol. 2017 Feb;8(1):199-212.
Title:	Current companion diagnostics in advanced colorectal cancer; getting a bigger and better piece of the pie.
Author:	Loree, Jonathan M\|Kopetz, Scott\|Raghav, Kanwal P S
PMID:	28280626

1665.
Journal:	Cancer Sci. 2017 Jun;108(6):1135-1143.
Title:	BRAF mutations are associated with increased iron regulatory protein-2 expression in colorectal tumorigenesis.
Author:	Horniblow, Richard D\|Bedford, Matthew\|Hollingworth, Robert\|Evans, Sarah\|Sutton, Emily\|Lal, Neeraj\|Beggs, Andrew\|Iqbal, Tariq H\|Tselepis, Chris
PMID:	28281325

1666.
Journal:	Int J Mol Sci. 2017 Mar 8;18(3). pii: ijms18030585.
Title:	Strategies for Overcoming Resistance in Tumours Harboring BRAF Mutations.
Author:	Obaid, Nourah Mohammad\|Bedard, Karen\|Huang, Weei-Yuarn
PMID:	28282860

1667.
Journal:	J Clin Pathol. 2017 Jul;70(7):610-614.
Title:	Validating a fully automated real-time PCR-based system for use in the molecular diagnostic analysis of colorectal carcinoma: a comparison with NGS and IHC.
Author:	Colling, Richard\|Wang, Lai Mun\|Soilleux, Elizabeth
PMID:	28292978

1668.
Journal:	Anticancer Res. 2017 Mar;37(3):1105-1112.
Title:	Identification of Methylation Profiles of Cancer-related Genes in Circulating Tumor Cells Population.
Author:	Lyberopoulou, Anna\|Galanopoulos, Michail\|Aravantinos, Gerasimos\|Theodoropoulos, George E\|Marinos, Evangelos\|Efstathopoulos, Efstathios P\|Gazouli, Maria
PMID:	28314271

1669.
Journal:	Anticancer Res. 2017 Mar;37(3):1349-1357.
Title:	KRAS Mutant Status May Be Associated with Distant Recurrence in Early-stage Rectal Cancer.
Author:	Sideris, Michail\|Moorhead, Jane\|Diaz-Cano, Salvador\|Haji, Amyn\|Papagrigoriadis, Savvas
PMID:	28314302

1670.
Journal:	Cancer Prev Res (Phila). 2017 May;10(5):270-278.
Title:	Sessile Serrated Polyps and Colon Cancer Prevention.
Author:	Rashtak, Shahrooz\|Rego, Rafaela\|Sweetser, Seth R\|Sinicrope, Frank A
PMID:	28325827

1671.
Journal:	Ann Oncol. 2017 Jun 1;28(6):1359-1367.
Title:	Predicted vitamin D status and colon cancer recurrence and mortality in CALGB 89803 (Alliance).
Author:	Fuchs, M A\|Yuan, C\|Sato, K\|Niedzwiecki, D\|Ye, X\|Saltz, L B\|Mayer, R J\|Mowat, R B\|Whittom, R\|Hantel, A\|Benson, A\|Atienza, D\|Messino, M\|Kindler, H\|Venook, A\|Innocenti, F\|Warren, R S\|Bertagnolli, M M\|Ogino, S\|Giovannucci, E L\|Horvath, E\|Meyerhardt, J A\|Ng, K
PMID:	28327908

1672.
Journal:	World J Gastrointest Oncol. 2017 Mar 15;9(3):105-120.
Title:	CpG island methylator phenotype in adenocarcinomas from the digestive tract: Methods, conclusions, and controversies.
Author:	Sanchez-Vega, Francisco\|Gotea, Valer\|Chen, Yun-Ching\|Elnitski, Laura
PMID:	28344746

1673.
Journal:	Tumour Biol. 2017 Mar;39(3):1010428317692246.
Title:	Mitochondrial DNA alteration in primary and metastatic colorectal cancer: Different frequency and association with selected clinicopathological and molecular markers.
Author:	Kleist, Britta\|Meurer, Thuja\|Poetsch, Micaela
PMID:	28345467

1674.
Journal:	Molecules. 2017 Mar 30;22(4). pii: molecules22040561.
Title:	Novel Palladium(II) Complexes that Influence Prominin-1/CD133 Expression and Stem Cell Factor Release in Tumor Cells.
Author:	Fischer-Fodor, Eva\|Miklas, Roman\|Risianova, Lucia\|Cenariu, Mihai\|Grosu, Ioana-Georgeta\|Virag, Piroska\|Perde-Schrepler, Maria\|Tomuleasa, Ciprian\|Berindan-Neagoe, Ioana\|Devinsky, Ferdinand\|Miklasova, Natalia
PMID:	28358339

1675.
Journal:	Cancer Discov. 2017 Jun;7(6):610-619.
Title:	A Phase Ib Dose-Escalation Study of Encorafenib and Cetuximab with or without Alpelisib in Metastatic BRAF-Mutant Colorectal Cancer.
Author:	van Geel, Robin M J M\|Tabernero, Josep\|Elez, Elena\|Bendell, Johanna C\|Spreafico, Anna\|Schuler, Martin\|Yoshino, Takayuki\|Delord, Jean-Pierre\|Yamada, Yasuhide\|Lolkema, Martijn P\|Faris, Jason E\|Eskens, Ferry A L M\|Sharma, Sunil\|Yaeger, Rona\|Lenz, Heinz-Josef
PMID:	28363909

1676.
Journal:	J BUON. 2017 Jan-Feb;22(1):178-183.
Title:	Cell-free DNA as biomarker and source for mutation detection in primary colorectal cancer.
Author:	Nikolic, Aleksandra\|Vlajnic, Marina\|Ristanovic, Momcilo\|Petrovic, Jelena\|Dimitrijevic, Ivan\|Krivokapic, Zoran\|Radojkovic, Dragica
PMID:	28365952

1677.
Journal:	Org Biomol Chem. 2017 Apr 18;15(16):3455-3465.
Title:	Rational design, synthesis, and biological evaluation of Pan-Raf inhibitors to overcome resistance.
Author:	Wang, Lu\|Zhu, Gaoyuan\|Zhang, Qing\|Duan, Chunqi\|Zhang, Yanmin\|Zhang, Zhimin\|Zhou, Yujun\|Lu, Tao\|Tang, Weifang
PMID:	28368067

1678.
Journal:	Oncogenesis. 2017 Apr 3;6(4):e308.
Title:	Methylation of WNT target genes AXIN2 and DKK1 as robust biomarkers for recurrence prediction in stage II colon cancer.
Author:	Kandimalla, R\|Linnekamp, J F\|van Hooff, S\|Castells, A\|Llor, X\|Andreu, M\|Jover, R\|Goel, A\|Medema, J P
PMID:	28368388

1679.
Journal:	Cancer Med. 2017 May;6(5):1023-1035.
Title:	DNA methylation epigenotype and clinical features of NRAS-mutation(+) colorectal cancer.
Author:	Takane, Kiyoko\|Akagi, Kiwamu\|Fukuyo, Masaki\|Yagi, Koichi\|Takayama, Tadatoshi\|Kaneda, Atsushi
PMID:	28378457

1680.
Journal:	Cancer Med. 2017 May;6(5):928-936.
Title:	The prognostic value of simultaneous tumor and serum RAS/RAF mutations in localized colon cancer.
Author:	Thomsen, Caroline Emilie B\|Appelt, Ane Lindegaard\|Andersen, Rikke Fredslund\|Lindebjerg, Jan\|Jensen, Lars Henrik\|Jakobsen, Anders
PMID:	28378527

1681.
Journal:	Handb Exp Pharmacol. 2017 Apr 6.
Title:	Plasticity of Resistance and Sensitivity to Anti-Epidermal Growth Factor Receptor Inhibitors in Metastatic Colorectal Cancer.
Author:	Sartore-Bianchi, Andrea\|Siena, Salvatore
PMID:	28382467

1682.
Journal:	Clin Cancer Res. 2017 Aug 15;23(16):4578-4591.
Title:	Circulating DNA Demonstrates Convergent Evolution and Common Resistance Mechanisms during Treatment of Colorectal Cancer.
Author:	Thierry, Alain R\|Pastor, Brice\|Jiang, Zhi-Qin\|Katsiampoura, Anastasia D\|Parseghian, Christine\|Loree, Jonathan M\|Overman, Michael J\|Sanchez, Cynthia\|Messaoudi, Safia El\|Ychou, Marc\|Kopetz, Scott
PMID:	28400427

1683.
Journal:	Oncoimmunology. 2017 Jan 31;6(3):e1284720.
Title:	Tumor SQSTM1 (p62) expression and T cells in colorectal cancer.
Author:	Kosumi, Keisuke\|Masugi, Yohei\|Yang, Juhong\|Qian, Zhi Rong\|Kim, Sun A\|Li, Wanwan\|Shi, Yan\|da Silva, Annacarolina\|Hamada, Tsuyoshi\|Liu, Li\|Gu, Mancang\|Twombly, Tyler S\|Cao, Yin\|Barbie, David A\|Nosho, Katsuhiko\|Baba, Hideo\|Garrett, Wendy S\|Meyerhardt, Jeffer
PMID:	28405513

1684.
Journal:	Cancer Immunol Immunother. 2017 Jul;66(7):927-939.
Title:	Prognostic implication of CD274 (PD-L1) protein expression in tumor-infiltrating immune cells for microsatellite unstable and stable colorectal cancer.
Author:	Lee, Kyu Sang\|Kwak, Yoonjin\|Ahn, Soyeon\|Shin, Eun\|Oh, Heung-Kwon\|Kim, Duck-Woo\|Kang, Sung-Bum\|Choe, Gheeyoung\|Kim, Woo Ho\|Lee, Hye Seung
PMID:	28405764

1685.
Journal:	J Clin Oncol. 2017 Jun 1;35(16):1836-1844.
Title:	Aspirin Use and Colorectal Cancer Survival According to Tumor CD274 (Programmed Cell Death 1 Ligand 1) Expression Status.
Author:	Hamada, Tsuyoshi\|Cao, Yin\|Qian, Zhi Rong\|Masugi, Yohei\|Nowak, Jonathan A\|Yang, Juhong\|Song, Mingyang\|Mima, Kosuke\|Kosumi, Keisuke\|Liu, Li\|Shi, Yan\|da Silva, Annacarolina\|Gu, Mancang\|Li, Wanwan\|Keum, NaNa\|Zhang, Xuehong\|Wu, Kana\|Meyerhardt, Jeffrey A\|Giova
PMID:	28406723

1686.
Journal:	Oncotarget. 2017 May 2;8(18):30217-30234.
Title:	Mechanistic characterization of a copper containing thiosemicarbazone with potent antitumor activity.
Author:	Karlsson, Henning\|Fryknas, Marten\|Strese, Sara\|Gullbo, Joachim\|Westman, Gunnar\|Bremberg, Ulf\|Sjoblom, Tobias\|Pandzic, Tatjana\|Larsson, Rolf\|Nygren, Peter
PMID:	28415818

1687.
Journal:	Oncotarget. 2017 Jul 25;8(30):49076-49083.
Title:	The molecular heterogeneity of sporadic colorectal cancer with different tumor sites in Chinese patients.
Author:	Peng, Junjie\|Huang, Dan\|Poston, Graeme\|Ma, Xiaoji\|Wang, Renjie\|Sheng, Weiqi\|Zhou, Xiaoyan\|Zhu, Xiaoli\|Cai, Sanjun
PMID:	28416767

1688.
Journal:	Adv Healthc Mater. 2017 Jul;6(13).
Title:	Panitumumab-Conjugated Pt-Drug Nanomedicine for Enhanced Efficacy of Combination Targeted Chemotherapy against Colorectal Cancer.
Author:	Tsai, Ming-Hsien\|Pan, Chao-Hsuan\|Peng, Cheng-Liang\|Shieh, Ming-Jium
PMID:	28418176

1689.
Journal:	Oncotarget. 2017 Jun 13;8(24):39268-39279.
Title:	FBXW7 missense mutation: a novel negative prognostic factor in metastatic colorectal adenocarcinoma.
Author:	Korphaisarn, Krittiya\|Morris, Van Karlyle\|Overman, Michael J\|Fogelman, David R\|Kee, Bryan K\|Raghav, Kanwal Pratap Singh\|Manuel, Shanequa\|Shureiqi, Imad\|Wolff, Robert A\|Eng, Cathy\|Menter, David\|Hamilton, Stanley R\|Kopetz, Scott\|Dasari, Arvind
PMID:	28424412

1690.
Journal:	Int J Colorectal Dis. 2017 Aug;32(8):1179-1190.
Title:	Final analysis of the randomised PEAK trial: overall survival and tumour responses during first-line treatment with mFOLFOX6 plus either panitumumab or bevacizumab in patients with metastatic colorectal carcinoma.
Author:	Rivera, Fernando\|Karthaus, Meinolf\|Hecht, J Randolph\|Sevilla, Isabel\|Forget, Frederic\|Fasola, Gianpiero\|Canon, Jean-Luc\|Guan, Xuesong\|Demonty, Gaston\|Schwartzberg, Lee S
PMID:	28424871

1691.
Journal:	Mod Pathol. 2017 Aug;30(8):1177-1189.
Title:	Mapping clinicopathological entities within colorectal mucinous adenocarcinomas: a hierarchical clustering approach.
Author:	Liddell, Charly\|Droy-Dupre, Laure\|Metairie, Sylvie\|Airaud, Fabrice\|Volteau, Christelle\|Bezieau, Stephane\|Laboisse, Christian L\|Mosnier, Jean-Francois
PMID:	28429715

1692.
Journal:	Pathology. 2017 Jun;49(4):387-390.
Title:	NRASQ61R immunohistochemistry detects both NRASQ61R and KRASQ61R mutations in colorectal cancer.
Author:	Jhuang, Jie-Yang\|Yuan, Chang-Tsu\|Lin, Yu-Lin\|Cheng, Mei-Ling\|Liau, Jau-Yu\|Tsai, Jia-Huei
PMID:	28433252

1693.
Journal:	Hum Pathol. 2017 Jun;64:179-185.
Title:	Clinicopathological, immunohistochemical, and mutational analyses of pulmonary enteric adenocarcinoma: usefulness of SATB2 and beta-catenin immunostaining for differentiation from metastatic colorectal carcinoma.
Author:	Matsushima, Jun\|Yazawa, Takuya\|Suzuki, Masaki\|Takahashi, Yoko\|Ota, Satoshi\|Nakajima, Takahiro\|Yoshino, Ichiro\|Yokose, Tomoyuki\|Inoue, Toru\|Kawahara, Kunimitsu\|Nakatani, Yukio
PMID:	28438615

1694.
Journal:	Acta Oncol. 2017 May;56(5):639-645.
Title:	Risk factors for brain metastases in patients with metastatic colorectal cancer.
Author:	Christensen, Troels Dreier\|Palshof, Jesper Andreas\|Larsen, Finn Ole\|Hogdall, Estrid\|Poulsen, Tim Svenstrup\|Pfeiffer, Per\|Jensen, Benny Vittrup\|Yilmaz, Mette Karen\|Christensen, Ib Jarle\|Nielsen, Dorte
PMID:	28447565

1695.
Journal:	Ann Oncol. 2017 May 1;28(5):958-968.
Title:	Subgroups and prognostication in stage III colon cancer: future perspectives for adjuvant therapy.
Author:	Auclin, E\|Zaanan, A\|Vernerey, D\|Douard, R\|Gallois, C\|Laurent-Puig, P\|Bonnetain, F\|Taieb, J
PMID:	28453690

1696.
Journal:	Ann Oncol. 2017 May 1;28(5):1023-1031.
Title:	Prediction of overall survival in stage II and III colon cancer beyond TNM system: a retrospective, pooled biomarker study.
Author:	Dienstmann, R\|Mason, M J\|Sinicrope, F A\|Phipps, A I\|Tejpar, S\|Nesbakken, A\|Danielsen, S A\|Sveen, A\|Buchanan, D D\|Clendenning, M\|Rosty, C\|Bot, B\|Alberts, S R\|Milburn Jessup, J\|Lothe, R A\|Delorenzi, M\|Newcomb, P A\|Sargent, D\|Guinney, J
PMID:	28453697

1697.
Journal:	Oncogene. 2017 Aug 31;36(35):4975-4986.
Title:	Oncogenic KRAS-associated gene signature defines co-targeting of CDK4/6 and MEK as a viable therapeutic strategy in colorectal cancer.
Author:	Pek, M\|Yatim, S M J M\|Chen, Y\|Li, J\|Gong, M\|Jiang, X\|Zhang, F\|Zheng, J\|Wu, X\|Yu, Q
PMID:	28459468

1698.
Journal:	J Biol Chem. 2017 Jun 16;292(24):10142-10152.
Title:	HMG-CoA synthase 1 is a synthetic lethal partner of BRAF(V600E) in human cancers.
Author:	Zhao, Liang\|Fan, Jun\|Xia, Siyuan\|Pan, Yaozhu\|Liu, Shuangping\|Qian, Guoqing\|Qian, Zhiyu\|Kang, Hee-Bum\|Arbiser, Jack L\|Pollack, Brian P\|Kudchadkar, Ragini R\|Lawson, David H\|Rossi, Michael\|Abdel-Wahab, Omar\|Merghoub, Taha\|Khoury, Hanna J\|Khuri, Fadlo R\|Boise
PMID:	28468827

1699.
Journal:	Cancer Med. 2017 Jun;6(6):1465-1472.
Title:	Screening for mismatch repair deficiency in colorectal cancer: data from three academic medical centers.
Author:	O'Kane, Grainne M\|Ryan, Eanna\|McVeigh, Terri P\|Creavin, Ben\|Hyland, John Mp\|O'Donoghue, Diarmuid P\|Keegan, Denise\|Geraghty, Robert\|Flannery, Delia\|Nolan, Carmel\|Donovan, Emily\|Mehigan, Brian J\|McCormick, Paul\|Muldoon, Cian\|Farrell, Michael\|Shields, Conor\|
PMID:	28470797

1700.
Journal:	J Clin Oncol. 2017 Aug 10;35(23):2624-2630.
Title:	(Non-V600) BRAF Mutations Define a Clinically Distinct Molecular Subtype of Metastatic Colorectal Cancer.
Author:	Jones, Jeremy C\|Renfro, Lindsay A\|Al-Shamsi, Humaid O\|Schrock, Alexa B\|Rankin, Andrew\|Zhang, Ben Y\|Kasi, Pashtoon M\|Voss, Jesse S\|Leal, Alexis D\|Sun, James\|Ross, Jeffrey\|Ali, Siraj M\|Hubbard, Joleen M\|Kipp, Benjamin R\|McWilliams, Robert R\|Kopetz, Scott\|Wo
PMID:	28486044

1701.
Journal:	Gastrointest Endosc. 2017 Dec;86(6):1131-1138.e4.
Title:	Endoscopic and molecular characterization of colorectal sessile serrated adenoma/polyps with cytologic dysplasia.
Author:	Tanaka, Yoshihito\|Yamano, Hiro-O\|Yamamoto, Eiichiro\|Matushita, Hiro-O\|Aoki, Hironori\|Yoshikawa, Kenjiro\|Takagi, Ryo\|Harada, Eiji\|Nakaoka, Michiko\|Yoshida, Yuko\|Eizuka, Makoto\|Sugai, Tamotsu\|Suzuki, Hiromu\|Nakase, Hiroshi
PMID:	28501592

1702.
Journal:	Target Oncol. 2017 Jun;12(3):265-275.
Title:	What We Know About Stage II and III Colon Cancer: It's Still Not Enough.
Author:	Puccini, Alberto\|Berger, Martin D\|Zhang, Wu\|Lenz, Heinz-Josef
PMID:	28504299

1703.
Journal:	Oncologist. 2017 Jul;22(7):774-779.
Title:	Detection of an ALK Fusion in Colorectal Carcinoma by Hybrid Capture-Based Assay of Circulating Tumor DNA.
Author:	Lai, Andrea Z\|Schrock, Alexa B\|Erlich, Rachel L\|Ross, Jeffrey S\|Miller, Vincent A\|Yakirevich, Evgeny\|Ali, Siraj M\|Braiteh, Fadi
PMID:	28507204

1704.
Journal:	J Cancer Res Ther. 2017 Jan-Mar;13(1):156.
Title:	Retraction: Evaluation and identification of factors related to KRAS and BRAF gene mutations in colorectal cancer: A meta analysis.
Author:
PMID:	28508855

1705.
Journal:	Cancer Res. 2017 Jul 15;77(14):3814-3822.
Title:	A Systematic Analysis of Oncogenic Gene Fusions in Primary Colon Cancer.
Author:	Kloosterman, Wigard P\|Coebergh van den Braak, Robert R J\|Pieterse, Mark\|van Roosmalen, Markus J\|Sieuwerts, Anieta M\|Stangl, Christina\|Brunekreef, Ronne\|Lalmahomed, Zarina S\|Ooft, Salo\|van Galen, Anne\|Smid, Marcel\|Lefebvre, Armel\|Zwartkruis, Fried\|Martens,
PMID:	28512242

1706.
Journal:	Cancer. 2017 Sep 15;123(18):3513-3523.
Title:	Association between mutations of critical pathway genes and survival outcomes according to the tumor location in colorectal cancer.
Author:	Lee, Dae-Won\|Han, Sae-Won\|Cha, Yongjun\|Bae, Jeong Mo\|Kim, Hwang-Phill\|Lyu, Jaemyun\|Han, Hyojun\|Kim, Hyoki\|Jang, Hoon\|Bang, Duhee\|Huh, Iksoo\|Park, Taesung\|Won, Jae-Kyung\|Jeong, Seung-Yong\|Park, Kyu Joo\|Kang, Gyeong Hoon\|Kim, Tae-You
PMID:	28513830

1707.
Journal:	Oncol Lett. 2017 May;13(5):3608-3616.
Title:	KRAS and BRAF mutations in serum exosomes from patients with colorectal cancer in a Chinese population.
Author:	Hao, Yi-Xin\|Li, Yong-Mei\|Ye, Ming\|Guo, Yan-Yan\|Li, Qiu-Wen\|Peng, Xiu-Mei\|Wang, Qi\|Zhang, Shu-Fang\|Zhao, Hui-Xia\|Zhang, He\|Li, Guang-Hui\|Zhu, Jian-Hua\|Xiao, Wen-Hua
PMID:	28521461

1708.
Journal:	Biomed Res Int. 2017;2017:3926498.
Title:	Identification of "BRAF-Positive" Cases Based on Whole-Slide Image Analysis.
Author:	Popovici, Vlad\|Krenek, Ales\|Budinska, Eva
PMID:	28523274

1709.
Journal:	Biochem Biophys Res Commun. 2017 Jul 15;489(1):14-20.
Title:	AKT is critically involved in the antagonism of BRAF inhibitor sorafenib against dabrafenib in colorectal cancer cells harboring both wild-type and mutant (V600E) BRAF genes.
Author:	Wang, Hongbin\|Quan, Haitian\|Lou, Liguang
PMID:	28536078

1710.
Journal:	Yonsei Med J. 2017 Jul;58(4):749-755.
Title:	Lack of Aberrant Methylation in an Adjacent Area of Left-Sided Colorectal Cancer.
Author:	Sambuudash, Otgontuya\|Kim, Hyun Soo\|Cho, Mee Yon
PMID:	28540987

1711.
Journal:	Int J Cancer. 2017 Sep 1;141(5):967-976.
Title:	CpG island methylator phenotype identifies high risk patients among microsatellite stable BRAF mutated colorectal cancers.
Author:	Vedeld, Hege Marie\|Merok, Marianne\|Jeanmougin, Marine\|Danielsen, Stine A\|Honne, Hilde\|Presthus, Gro Kummeneje\|Svindland, Aud\|Sjo, Ole H\|Hektoen, Merete\|Eknaes, Mette\|Nesbakken, Arild\|Lothe, Ragnhild A\|Lind, Guro E
PMID:	28542846

1712.
Journal:	Cancer Med. 2017 Jun;6(6):1255-1263.
Title:	Predictive model for high-frequency microsatellite instability in colorectal cancer patients over 50 years of age.
Author:	Fujiyoshi, Kenji\|Yamaguchi, Tatsuro\|Kakuta, Miho\|Takahashi, Akemi\|Arai, Yoshiko\|Yamada, Mina\|Yamamoto, Gou\|Ohde, Sachiko\|Takao, Misato\|Horiguchi, Shin-Ichiro\|Natsume, Soichiro\|Kazama, Shinsuke\|Nishizawa, Yusuke\|Nishimura, Yoji\|Akagi, Yoshito\|Sakamoto, Hir
PMID:	28544821

1713.
Journal:	Anticancer Res. 2017 Jun;37(6):2831-2838.
Title:	MEK162 Enhances Antitumor Activity of 5-Fluorouracil and Trifluridine in KRAS-mutated Human Colorectal Cancer Cell Lines.
Author:	Gong, Jun\|Chen, Yuan\|Yang, Lixin\|Pillai, Raju\|Shirasawa, Senji\|Fakih, Marwan
PMID:	28551618

1714.
Journal:	World J Gastrointest Oncol. 2017 May 15;9(5):209-217.
Title:	Extramural vascular invasion and response to neoadjuvant chemoradiotherapy in rectal cancer: Influence of the CpG island methylator phenotype.
Author:	Williamson, Jeremy Stuart\|Jones, Huw Geraint\|Williams, Namor\|Griffiths, Anthony Paul\|Jenkins, Gareth\|Beynon, John\|Harris, Dean Anthony
PMID:	28567185

1715.
Journal:	Cancer Lett. 2017 Aug 28;402:100-109.
Title:	Targeting of super-enhancers and mutant BRAF can suppress growth of BRAF-mutant colon cancer cells via repression of MAPK signaling pathway.
Author:	Nakamura, Yoshiaki\|Hattori, Naoko\|Iida, Naoko\|Yamashita, Satoshi\|Mori, Akiko\|Kimura, Kana\|Yoshino, Takayuki\|Ushijima, Toshikazu
PMID:	28576751

1716.
Journal:	Cancer Discov. 2017 Jun;7(6):558-560.
Title:	Targeting BRAF-Mutant Colorectal Cancer: Progress in Combination Strategies.
Author:	Sundar, Raghav\|Hong, David S\|Kopetz, Scott\|Yap, Timothy A
PMID:	28576843

1717.
Journal:	Cell J. 2017 Spring;19(Suppl 1):113-117.
Title:	Coexistence of KRAS and BRAF Mutations in Colorectal Cancer: A Case Report Supporting The Concept of Tumoral Heterogeneity.
Author:	Larki, Pegah\|Gharib, Ehsan\|Yaghoob Taleghani, Mohammad\|Khorshidi, Fatemeh\|Nazemalhosseini-Mojarad, Ehsan\|Asadzadeh Aghdaei, Hamid
PMID:	28580315

1718.
Journal:	BMC Cancer. 2017 Jun 5;17(1):403.
Title:	The prognostic significance of KRAS and BRAF mutation status in Korean colorectal cancer patients.
Author:	Won, Daeyoun David\|Lee, Jae Im\|Lee, In Kyu\|Oh, Seong-Taek\|Jung, Eun Sun\|Lee, Sung Hak
PMID:	28583095

1719.
Journal:	Virchows Arch. 2017 Sep;471(3):329-336.
Title:	Intratumoral Fusobacterium nucleatum abundance correlates with macrophage infiltration and CDKN2A methylation in microsatellite-unstable colorectal carcinoma.
Author:	Park, Hye Eun\|Kim, Jung Ho\|Cho, Nam-Yun\|Lee, Hye Seung\|Kang, Gyeong Hoon
PMID:	28597080

1720.
Journal:	Int J Mol Sci. 2017 Jun 9;18(6). pii: ijms18061240.
Title:	Right- vs. Left-Sided Metastatic Colorectal Cancer: Differences in Tumor Biology and Bevacizumab Efficacy.
Author:	Ulivi, Paola\|Scarpi, Emanuela\|Chiadini, Elisa\|Marisi, Giorgia\|Valgiusti, Martina\|Capelli, Laura\|Casadei Gardini, Andrea\|Monti, Manlio\|Ruscelli, Silvia\|Frassineti, Giovanni Luca\|Calistri, Daniele\|Amadori, Dino\|Passardi, Alessandro
PMID:	28598398

1721.
Journal:	Clin Cancer Res. 2017 Sep 1;23(17):5267-5280.
Title:	Targeting the Wnt Pathway and Cancer Stem Cells with Anti-progastrin Humanized Antibodies as a Potential Treatment for K-RAS-Mutated Colorectal Cancer.
Author:	Prieur, Alexandre\|Cappellini, Monica\|Habif, Guillaume\|Lefranc, Marie-Paule\|Mazard, Thibault\|Morency, Eric\|Pascussi, Jean-Marc\|Flaceliere, Maud\|Cahuzac, Nathalie\|Vire, Berengere\|Dubuc, Benjamin\|Durochat, Amandine\|Liaud, Pierre\|Ollier, Jeremy\|Pfeiffer, Caro
PMID:	28600477

1722.
Journal:	Mol Cancer Ther. 2017 Oct;16(10):2178-2190.
Title:	A Novel Combination Treatment Targeting BCL-XL and MCL1 for KRAS/BRAF-mutated and BCL2L1-amplified Colorectal Cancers.
Author:	Cho, Sung-Yup\|Han, Jee Yun\|Na, Deukchae\|Kang, Wonyoung\|Lee, Ahra\|Kim, Jooyoung\|Lee, Jieun\|Min, Seoyeon\|Kang, Jinjoo\|Chae, Jeesoo\|Kim, Jong-Il\|Park, Hansoo\|Lee, Won-Suk\|Lee, Charles
PMID:	28611106

1723.
Journal:	Clin Cancer Res. 2017 Sep 15;23(18):5547-5560.
Title:	Mouse PDX Trial Suggests Synergy of Concurrent Inhibition of RAF and EGFR in Colorectal Cancer with BRAF or KRAS Mutations.
Author:	Yao, Yung-Mae M\|Donoho, Gregory P\|Iversen, Philip W\|Zhang, Youyan\|Van Horn, Robert D\|Forest, Amelie\|Novosiadly, Ruslan D\|Webster, Yue Wang\|Ebert, Philip\|Bray, Steven\|Ting, Jason C\|Aggarwal, Amit\|Henry, James R\|Tiu, Ramon V\|Plowman, Gregory D\|Peng, Sheng-B
PMID:	28611205

1724.
Journal:	Saudi J Gastroenterol. 2017 May-Jun;23(3):144-149.
Title:	BRAF mutation is associated with poor clinicopathological outcomes in colorectal cancer: A meta-analysis.
Author:	Li, Yujie\|Li, Weier
PMID:	28611337

1725.
Journal:	J Clin Oncol. 2017 Aug 20;35(24):2806-2813.
Title:	Timing of Aspirin and Other Nonsteroidal Anti-Inflammatory Drug Use Among Patients With Colorectal Cancer in Relation to Tumor Markers and Survival.
Author:	Hua, Xinwei\|Phipps, Amanda I\|Burnett-Hartman, Andrea N\|Adams, Scott V\|Hardikar, Sheetal\|Cohen, Stacey A\|Kocarnik, Jonathan M\|Ahnen, Dennis J\|Lindor, Noralane M\|Baron, John A\|Newcomb, Polly A
PMID:	28617623

1726.
Journal:	JAMA Oncol. 2017 Nov 1;3(11):1546-1553.
Title:	Genomic Profiling of Small-Bowel Adenocarcinoma.
Author:	Schrock, Alexa B\|Devoe, Craig E\|McWilliams, Robert\|Sun, James\|Aparicio, Thomas\|Stephens, Philip J\|Ross, Jeffrey S\|Wilson, Richard\|Miller, Vincent A\|Ali, Siraj M\|Overman, Michael J
PMID:	28617917

1727.
Journal:	Mol Oncol. 2017 Sep;11(9):1263-1272.
Title:	Analysis of mutant allele fractions in driver genes in colorectal cancer - biological and clinical insights.
Author:	Dienstmann, Rodrigo\|Elez, Elena\|Argiles, Guillem\|Matos, Ignacio\|Sanz-Garcia, Enrique\|Ortiz, Carolina\|Macarulla, Teresa\|Capdevila, Jaume\|Alsina, Maria\|Sauri, Tamara\|Verdaguer, Helena\|Vilaro, Marta\|Ruiz-Pace, Fiorella\|Viaplana, Cristina\|Garcia, Ariadna\|Land
PMID:	28618197

1728.
Journal:	Br J Cancer. 2017 Jul 25;117(3):358-366.
Title:	Extreme assay sensitivity in molecular diagnostics further unveils intratumour heterogeneity in metastatic colorectal cancer as well as artifactual low-frequency mutations in the KRAS gene.
Author:	Mariani, Sara\|Bertero, Luca\|Osella-Abate, Simona\|Di Bello, Cristiana\|Francia di Celle, Paola\|Coppola, Vittoria\|Sapino, Anna\|Cassoni, Paola\|Marchio, Caterina
PMID:	28618430

1729.
Journal:	BMC Bioinformatics. 2017 Jun 17;18(1):304.
Title:	Biomarker correlation network in colorectal carcinoma by tumor anatomic location.
Author:	Nishihara, Reiko\|Glass, Kimberly\|Mima, Kosuke\|Hamada, Tsuyoshi\|Nowak, Jonathan A\|Qian, Zhi Rong\|Kraft, Peter\|Giovannucci, Edward L\|Fuchs, Charles S\|Chan, Andrew T\|Quackenbush, John\|Ogino, Shuji\|Onnela, Jukka-Pekka
PMID:	28623901

1730.
Journal:	Lung Cancer. 2017 Jun;108:62-65.
Title:	Investigation of patterns of nodal metastases in BRAF mutant lung cancer.
Author:	McEvoy, S H\|Halpenny, D F\|Viteri-Jusue, A\|Hayes, S A\|Plodkowski, A J\|Riely, G J\|Ginsberg, M S
PMID:	28625649

1731.
Journal:	Br J Cancer. 2017 Jul 25;117(3):315-321.
Title:	The role of primary tumour sidedness, EGFR gene copy number and EGFR promoter methylation in RAS/BRAF wild-type colorectal cancer patients receiving irinotecan/cetuximab.
Author:	Demurtas, Laura\|Puzzoni, Marco\|Giampieri, Riccardo\|Ziranu, Pina\|Pusceddu, Valeria\|Mandolesi, Alessandra\|Cremolini, Chiara\|Masi, Gianluca\|Gelsomino, Fabio\|Antoniotti, Carlotta\|Loretelli, Cristian\|Meriggi, Fausto\|Zaniboni, Alberto\|Falcone, Alfredo\|Cascinu,
PMID:	28632725

1732.
Journal:	Mol Diagn Ther. 2017 Oct;21(5):571-579.
Title:	Significant Improvement in Detecting BRAF, KRAS, and EGFR Mutations Using Next-Generation Sequencing as Compared with FDA-Cleared Kits.
Author:	Ma, Wanlong\|Brodie, Steven\|Agersborg, Sally\|Funari, Vincent A\|Albitar, Maher
PMID:	28639239

1733.
Journal:	J La State Med Soc. 2017 May-Jun;169(3):78-82. Epub 2017 Jun 23.
Title:	Clinical Case of the Month: A 57-Year-Old Man with an Axillary Mass.
Author:	Desai, Palak\|Myers, Andrew\|Boulmay, Brian\|Lopez, Fred A
PMID:	28644156

1734.
Journal:	Life Sci. 2017 Aug 15;183:37-44.
Title:	Discovery of a novel pan-RAF inhibitor with potent anti-tumor activity in preclinical models of BRAF(V600E) mutant cancer.
Author:	Hong, Sung Pyo\|Ahn, Soon Kil
PMID:	28645859

1735.
Journal:	Eur J Epidemiol. 2017 May;32(5):409-418.
Title:	Associations of red and processed meat intake with major molecular pathological features of colorectal cancer.
Author:	Carr, Prudence R\|Jansen, Lina\|Bienert, Stefanie\|Roth, Wilfried\|Herpel, Esther\|Kloor, Matthias\|Blaker, Hendrik\|Chang-Claude, Jenny\|Brenner, Hermann\|Hoffmeister, Michael
PMID:	28646407

1736.
Journal:	Arch Iran Med. 2017 Jun;20(6):332-337.
Title:	Screening for Lynch Syndrome in Cases with Colorectal Carcinoma from Mashhad.
Author:	Goshayeshi, Ladan\|Khooiee, Alireza\|Ghaffarzadegan, Kamran\|Rahmani Khorram, Mahla\|Bishehsari, Faraz\|Hoseini, Benyamin\|Akhavan Rezayat, Kambiz\|Esmaeilzadeh, Abbas\|Mosannen Mozaffari, Hooman\|Ghanayee, Omid\|Lari, S\|Bahari, Ali\|Allahyari, Abolghasem\|Bari, Alir
PMID:	28646840

1737.
Journal:	NPJ Syst Biol Appl. 2017 Jun 2;3:14.
Title:	Clinical responses to ERK inhibition in BRAF(V600E)-mutant colorectal cancer predicted using a computational model.
Author:	Kirouac, Daniel C\|Schaefer, Gabriele\|Chan, Jocelyn\|Merchant, Mark\|Orr, Christine\|Huang, Shih-Min A\|Moffat, John\|Liu, Lichuan\|Gadkar, Kapil\|Ramanujan, Saroja
PMID:	28649441

1738.
Journal:	Eur J Cancer. 2017 Sep;82:16-24.
Title:	Prospective validation of a lymphocyte infiltration prognostic test in stage III colon cancer patients treated with adjuvant FOLFOX.
Author:	Emile, Jean-Francois\|Julie, Catherine\|Le Malicot, Karine\|Lepage, Come\|Tabernero, Josep\|Mini, Enrico\|Folprecht, Gunnar\|Van Laethem, Jean-Luc\|Dimet, Stephanie\|Boulagnon-Rombi, Camille\|Allard, Marc-Antoine\|Penault-Llorca, Frederique\|Bennouna, Jaafar\|Laurent-
PMID:	28651158

1739.
Journal:	Virchows Arch. 2017 Dec;471(6):721-729.
Title:	RAS screening in colorectal cancer: a comprehensive analysis of the results from the UK NEQAS colorectal cancer external quality assurance schemes (2009-2016).
Author:	Richman, Susan D\|Fairley, Jennifer\|Butler, Rachel\|Deans, Zandra C
PMID:	28653203

1740.
Journal:	Br J Cancer. 2017 Jul 25;117(3):347-352.
Title:	Emergence of MET hyper-amplification at progression to MET and BRAF inhibition in colorectal cancer.
Author:	Oddo, Daniele\|Siravegna, Giulia\|Gloghini, Annunziata\|Vernieri, Claudio\|Mussolin, Benedetta\|Morano, Federica\|Crisafulli, Giovanni\|Berenato, Rosa\|Corti, Giorgio\|Volpi, Chiara Costanza\|Buscarino, Michela\|Niger, Monica\|Dunne, Philip D\|Rospo, Giuseppe\|Valtorta
PMID:	28654634

1741.
Journal:	Mol Cancer Res. 2017 Oct;15(10):1431-1444.
Title:	BRAF-inhibitor Associated MEK Mutations Increase RAF-Dependent and -Independent Enzymatic Activity.
Author:	Emery, Caroline M\|Monaco, Kelli-Ann\|Wang, Ping\|Balak, Marissa\|Freeman, Alyson\|Meltzer, Jodi\|Delach, Scott M\|Rakiec, Daniel\|Ruddy, David A\|Korn, Joshua M\|Haling, Jacob\|Acker, Michael G\|Caponigro, Giordano
PMID:	28655712

1742.
Journal:	Oncol Rep. 2017 Aug;38(2):926-932.
Title:	Cetuximab promotes SN38 sensitivity via suppression of heat shock protein 27 in colorectal cancer cells with wild-type RAS.
Author:	Ishida, Takashi\|Ishii, Yoshiyuki\|Tsuruta, Masashi\|Okabayashi, Koji\|Akimoto, Shingo\|Koishikawa, Kaoru\|Hasegawa, Hirotoshi\|Kitagawa, Yuko
PMID:	28656305

1743.
Journal:	Mol Cancer. 2017 Jun 28;16(1):112.
Title:	PLX8394, a new generation BRAF inhibitor, selectively inhibits BRAF in colonic adenocarcinoma cells and prevents paradoxical MAPK pathway activation.
Author:	Tutuka, Candani S A\|Andrews, Miles C\|Mariadason, John M\|Ioannidis, Paul\|Hudson, Christopher\|Cebon, Jonathan\|Behren, Andreas
PMID:	28659148

1744.
Journal:	Tumour Biol. 2017 Jul;39(7):1010428317709638.
Title:	Oncogene mutation profile predicts tumor regression and survival in locally advanced rectal cancer patients treated with preoperative chemoradiotherapy and radical surgery.
Author:	Peng, Jianhong\|Lin, Junzhong\|Qiu, Miaozhen\|Zhao, Yujie\|Deng, Yuxiang\|Shao, Jianyong\|Ding, Peirong\|Zhang, Huizhong\|Wan, Desen\|Lu, Zhenhai\|Pan, Zhizhong
PMID:	28671043

1745.
Journal:	Int J Mol Sci. 2017 Jul 5;18(7). pii: ijms18071441.
Title:	Molecular and Clinicopathological Differences by Age at the Diagnosis of Colorectal Cancer.
Author:	Chang, Chu-Cheng\|Lin, Pei-Ching\|Lin, Chun-Chi\|Lan, Yuan-Tzu\|Lin, Hung-Hsin\|Lin, Chien-Hsing\|Yang, Shung-Haur\|Liang, Wen-Yi\|Chen, Wei-Shone\|Jiang, Jeng-Kai\|Lin, Jen-Kou\|Chang, Shih-Ching
PMID:	28678173

1746.
Journal:	Crit Rev Oncol Hematol. 2017 Aug;116:38-57.
Title:	The current value of determining the mismatch repair status of colorectal cancer: A rationale for routine testing.
Author:	Ryan, E\|Sheahan, K\|Creavin, B\|Mohan, H M\|Winter, D C
PMID:	28693799

1747.
Journal:	Int J Mol Epidemiol Genet. 2017 Jun 15;8(3):27-39. eCollection 2017.
Title:	Molecular genetic changes in benign colorectal tumors synchronous with microsatellite unstable carcinomas do not support a field defect.
Author:	Zauber, Peter\|Marotta, Stephen\|Sabbath-Solitare, Marlene
PMID:	28694923

1748.
Journal:	Mol Cancer Res. 2017 Oct;15(10):1445-1454.
Title:	EGFR Downregulation after Anti-EGFR Therapy Predicts the Antitumor Effect in Colorectal Cancer.
Author:	Okada, Yasuyuki\|Kimura, Tetsuo\|Nakagawa, Tadahiko\|Okamoto, Koichi\|Fukuya, Akira\|Goji, Takahiro\|Fujimoto, Shota\|Sogabe, Masahiro\|Miyamoto, Hiroshi\|Muguruma, Naoki\|Tsuji, Yasushi\|Okahisa, Toshiya\|Takayama, Tetsuji
PMID:	28698359

1749.
Journal:	Int J Mol Sci. 2017 Jul 14;18(7). pii: ijms18071522.
Title:	Pharmacogenomics of Targeted Agents for Personalization of Colorectal Cancer Treatment.
Author:	Bignucolo, Alessia\|De Mattia, Elena\|Cecchin, Erika\|Roncato, Rossana\|Toffoli, Giuseppe
PMID:	28708103

1750.
Journal:	Z Gastroenterol. 2017 Jul;55(7):667-674.
Title:	[Leptomeningeal carcinomatosis as a rare metastatic spreading of BRAF-mutated microsatellite stable colon cancer].
Author:	Hoblinger, Aksana\|Weber, Stephanie\|Tschirner, Florian\|Krober, Stefan\|Streetz, Konrad
PMID:	28709170

1751.
Journal:	Histopathology. 2017 Dec;71(6):1008-1011.
Title:	BRAF p.V600E-specific immunohistochemical assessment in colorectal cancer endoscopy biopsies is consistent with the mutational profiling.
Author:	Galuppini, Francesca\|Pennelli, Gianmaria\|Loupakis, Fotios\|Lanza, Cristiano\|Vianello, Luca\|Sacchi, Diana\|Mescoli, Claudia\|Salmaso, Roberta\|Agostini, Marco\|Lonardi, Sara\|Farinati, Fabio\|Rugge, Massimo\|Fassan, Matteo
PMID:	28722262

1752.
Journal:	J Gastrointest Oncol. 2017 Jun;8(3):387-404.
Title:	Personalized and precision medicine: integrating genomics into treatment decisions in gastrointestinal malignancies.
Author:	Au, Trang H\|Wang, Kai\|Stenehjem, David\|Garrido-Laguna, Ignacio
PMID:	28736627

1753.
Journal:	Rev Med Chil. 2017 Apr;145(4):419-430.
Title:	[Characterization of patients with sporadic colorectal cancer following the new Consensus Molecular Subtypes (CMS)].
Author:	Wielandt, Ana Maria\|Villarroel, Cynthia\|Hurtado, Claudia\|Simian, Daniela\|Zamorano, Diego\|Martinez, Maripaz\|Castro, Magdalena\|Vial, Maria Teresa\|Kronberg, Udo\|Lopez-Kostner, Francisco
PMID:	28748988

1754.
Journal:	Cell Biol Int. 2017 Oct;41(10):1127-1145.
Title:	Opposing effects of low versus high concentrations of water soluble vitamins/dietary ingredients Vitamin C and niacin on colon cancer stem cells (CSCs).
Author:	Sen, Utsav\|Shenoy P, Sudheer\|Bose, Bipasha
PMID:	28755485

1755.
Journal:	Ther Clin Risk Manag. 2017 Jul 21;13:915-918.
Title:	Thyroid cancer in a patient with Lynch syndrome - case report and literature review.
Author:	Fazekas-Lavu, Monika\|Parker, Andrew\|Spigelman, Allan D\|Scott, Rodney J\|Epstein, Richard J\|Jensen, Michael\|Samaras, Katherine
PMID:	28769567

1756.
Journal:	J Pathol Clin Res. 2017 Jul 19;3(3):203-213.
Title:	Immunoscore in mismatch repair-proficient and -deficient colon cancer.
Author:	Wirta, Erkki-Ville\|Seppala, Toni\|Friman, Marjukka\|Vayrynen, Juha\|Ahtiainen, Maarit\|Kautiainen, Hannu\|Kuopio, Teijo\|Kellokumpu, Ilmo\|Mecklin, Jukka-Pekka\|Bohm, Jan
PMID:	28770104

1757.
Journal:	Mol Cancer Ther. 2017 Nov;16(11):2340-2350.
Title:	A Bifunctional MAPK/PI3K Antagonist for Inhibition of Tumor Growth and Metastasis.
Author:	Galban, Stefanie\|Apfelbaum, April A\|Espinoza, Carlos\|Heist, Kevin\|Haley, Henry\|Bedi, Karan\|Ljungman, Mats\|Galban, Craig J\|Luker, Gary D\|Dort, Marcian Van\|Ross, Brian D
PMID:	28775144

1758.
Journal:	J Biomol Tech. 2017 Sep;28(3):97-110.
Title:	Squirrel Primer-Based PCR Assay for Direct and Targeted Sanger Sequencing of Short Genomic Segments.
Author:	Ebili, Henry O\|Hassall, James C\|Fadhil, Wakkas\|Ham-Karim, Hersh\|Asiri, Abutaleb\|Raposo, Teresa P\|Agboola, Ayodeji Johnson\|Ilyas, Mohammad
PMID:	28785174

1759.
Journal:	Front Oncol. 2017 Jul 25;7:160.
Title:	Potential Role of Metabolic Intervention in the Management of Advanced Differentiated Thyroid Cancer.
Author:	Tella, Sri Harsha\|Kommalapati, Anuhya\|Esquivel, Mary Angelynne\|Correa, Ricardo
PMID:	28791253

1760.
Journal:	Ther Adv Med Oncol. 2017 Aug;9(8):551-564.
Title:	Recent developments in the treatment of metastatic colorectal cancer.
Author:	Loree, Jonathan M\|Kopetz, Scott
PMID:	28794806

1761.
Journal:	Sci Rep. 2017 Aug 11;7(1):7882.
Title:	Differences of protein expression profiles, KRAS and BRAF mutation, and prognosis in right-sided colon, left-sided colon and rectal cancer.
Author:	Gao, Xian Hua\|Yu, Guan Yu\|Gong, Hai Feng\|Liu, Lian Jie\|Xu, Yi\|Hao, Li Qiang\|Liu, Peng\|Liu, Zhi Hong\|Bai, Chen Guang\|Zhang, Wei
PMID:	28801584

1762.
Journal:	Case Rep Oncol Med. 2017;2017:2321052.
Title:	Are All Mutations the Same? A Rare Case Report of Coexisting Mutually Exclusive KRAS and BRAF Mutations in a Patient with Metastatic Colon Adenocarcinoma.
Author:	Vittal, Anusha\|Middinti, Akshay\|Kasi Loknath Kumar, Anup
PMID:	28811946

1763.
Journal:	J Cancer. 2017 Jul 20;8(12):2263-2268.
Title:	MAP2K1 Mutation in Colorectal Cancer Patients: Therapeutic Challenge Using Patient-Derived Tumor Cell Lines.
Author:	Kim, J E\|Kim, K K\|Kim, S Y\|Lee, J\|Park, S H\|Park, J O\|Park, Y S\|Lim, H Y\|Kang, W K\|Kim, S T
PMID:	28819429

1764.
Journal:	Case Rep Pathol. 2017;2017:3427343.
Title:	Gastric Medullary Carcinoma with Sporadic Mismatch Repair Deficiency and a TP53 R273C Mutation: An Unusual Case with Wild-Type BRAF.
Author:	Lowenthal, Brett M\|Chan, Theresa W\|Thorson, John A\|Kelly, Kaitlyn J\|Savides, Thomas J\|Valasek, Mark A
PMID:	28840050

1765.
Journal:	Int J Mol Sci. 2017 Aug 29;18(9). pii: ijms18091871.
Title:	Measurement of Telomere Length in Colorectal Cancers for Improved Molecular Diagnosis.
Author:	Balc'h, Eric Le\|Grandin, Nathalie\|Demattei, Marie-Veronique\|Guyetant, Serge\|Tallet, Anne\|Pages, Jean-Christophe\|Ouaissi, Mehdi\|Lecomte, Thierry\|Charbonneau, Michel
PMID:	28850092

1766.
Journal:	Int J Cancer. 2017 Dec 15;141(12):2471-2479.
Title:	Tumor expression of calcium sensing receptor and colorectal cancer survival: Results from the nurses' health study and health professionals follow-up study.
Author:	Momen-Heravi, Fatemeh\|Masugi, Yohei\|Qian, Zhi Rong\|Nishihara, Reiko\|Liu, Li\|Smith-Warner, Stephanie A\|Keum, NaNa\|Zhang, Lanjing\|Tchrakian, Nairi\|Nowak, Jonathan A\|Yang, Wanshui\|Ma, Yanan\|Bowden, Michaela\|da Silva, Annacarolina\|Wang, Molin\|Fuchs, Charles S
PMID:	28856682

1767.
Journal:	Br J Cancer. 2017 Oct 24;117(9):1286-1294.
Title:	Preoperative chemoradiation with capecitabine, irinotecan and cetuximab in rectal cancer: significance of pre-treatment and post-resection RAS mutations.
Author:	Gollins, Simon\|West, Nick\|Sebag-Montefiore, David\|Myint, Arthur Sun\|Saunders, Mark\|Susnerwala, Shabbir\|Quirke, Phil\|Essapen, Sharadah\|Samuel, Leslie\|Sizer, Bruce\|Worlding, Jane\|Southward, Katie\|Hemmings, Gemma\|Tinkler-Hundal, Emma\|Taylor, Morag\|Bottomley,
PMID:	28859058

1768.
Journal:	Ann Ital Chir. 2017;6:425-432.
Title:	The prognostic role of microsatellite instability in colorectal cancer patients.
Author:	Micu, Bogdan V\|Andercou, Octavian\|Vesa, Stefan C\|Micu, Carmen M\|Pop, Tudor R\|Constantea, Nicolae
PMID:	28874631

1769.
Journal:	NPJ Syst Biol Appl. 2017 Sep 4;3:25.
Title:	Erratum: Clinical responses to ERK inhibition in BRAF(V600E)-mutant colorectal cancer predicted using a computational model.
Author:	Kirouac, Daniel C\|Schaefer, Gabriele\|Chan, Jocelyn\|Merchant, Mark\|Orr, Christine\|Huang, Shih-Min A\|Moffat, John\|Liu, Lichuan\|Gadkar, Kapil\|Ramanujan, Saroja
PMID:	28879057

1770.
Journal:	Cancer Biol Med. 2017 Aug;14(3):287-292.
Title:	BRAF mutation in colorectal carcinomas with signet ring cell component.
Author:	Yalcin, Serap\|Onguru, Onder
PMID:	28884045

1771.
Journal:	Health Technol Assess. 2017 Sep;21(51):1-238.
Title:	Molecular testing for Lynch syndrome in people with colorectal cancer: systematic reviews and economic evaluation.
Author:	Snowsill, Tristan\|Coelho, Helen\|Huxley, Nicola\|Jones-Hughes, Tracey\|Briscoe, Simon\|Frayling, Ian M\|Hyde, Chris
PMID:	28895526

1772.
Journal:	Oncotarget. 2017 Jun 14;8(34):57845-57854.
Title:	Implementation and utilization of the molecular tumor board to guide precision medicine.
Author:	Harada, Shuko\|Arend, Rebecca\|Dai, Qian\|Levesque, Jessica A\|Winokur, Thomas S\|Guo, Rongjun\|Heslin, Martin J\|Nabell, Lisle\|Nabors, L Burt\|Limdi, Nita A\|Roth, Kevin A\|Partridge, Edward E\|Siegal, Gene P\|Yang, Eddy S
PMID:	28915716

1773.
Journal:	J Cancer. 2017 Aug 23;8(14):2809-2815.
Title:	The Impact of Microsatellite Instability Status and Sidedness of the Primary Tumor on the Effect of Cetuximab-Containing Chemotherapy in Patients with Metastatic Colorectal Cancer.
Author:	Kim, Seung Tae\|Lee, Su-Jin\|Lee, Jeeyun\|Park, Se Hoon\|Park, Joon Oh\|Lim, Ho Yeong\|Kang, Won Ki\|Park, Young Suk
PMID:	28928870

1774.
Journal:	PLoS One. 2017 Sep 20;12(9):e0184900.
Title:	Methylation associated transcriptional repression of ELOVL5 in novel colorectal cancer cell lines.
Author:	Boot, Arnoud\|Oosting, Jan\|van Eendenburg, Jaap D H\|Kuppen, Peter J K\|Morreau, Hans\|van Wezel, Tom
PMID:	28931069

1775.
Journal:	Sci Rep. 2017 Sep 20;7(1):12020.
Title:	Ex vivo treatment of patient biopsies as a novel method to assess colorectal tumour response to the MEK1/2 inhibitor, Selumetinib.
Author:	Novo, Sonia M\|Wedge, Stephen R\|Stark, Lesley A
PMID:	28931905

1776.
Journal:	World J Gastroenterol. 2017 Aug 28;23(32):5913-5924.
Title:	Integrating TYMS, KRAS and BRAF testing in patients with metastatic colorectal cancer.
Author:	Ntavatzikos, Anastasios\|Spathis, Aris\|Patapis, Paul\|Machairas, Nikolaos\|Peros, George\|Konstantoudakis, Stefanos\|Leventakou, Danai\|Panayiotides, Ioannis G\|Karakitsos, Petros\|Koumarianou, Anna
PMID:	28932083

1777.
Journal:	Tumour Biol. 2017 Sep;39(9):1010428317724517.
Title:	EGFR pathway subgroups in Chilean colorectal cancer patients, detected by mutational and expression profiles, associated to different clinicopathological features.
Author:	Alvarez, Karin\|Orellana, Paulina\|Villarroel, Cynthia\|Contreras, Luis\|Kawachi, Hiroshi\|Kobayashi, Maki\|Wielandt, Ana Maria\|De la Fuente, Marjorie\|Trivino, Juan Carlos\|Kronberg, Udo\|Carvallo, Pilar\|Lopez-Kostner, Francisco
PMID:	28936923

1778.
Journal:	Cancer Lett. 2017 Dec 1;410:92-99.
Title:	Major challenges related to tumor biological characteristics in accurate mutation detection of colorectal cancer by next-generation sequencing.
Author:	Li, Weihua\|Qiu, Tian\|Guo, Lei\|Ying, Jianming
PMID:	28942013

1779.
Journal:	Cancer Lett. 2017 Dec 1;410:139-157.
Title:	Tubulin-binding anticancer polysulfides induce cell death via mitotic arrest and autophagic interference in colorectal cancer.
Author:	Yagdi Efe, Esma\|Mazumder, Aloran\|Lee, Jin-Young\|Gaigneaux, Anthoula\|Radogna, Flavia\|Nasim, Muhammad Jawad\|Christov, Christo\|Jacob, Claus\|Kim, Kyu-Won\|Dicato, Mario\|Chaimbault, Patrick\|Cerella, Claudia\|Diederich, Marc
PMID:	28943451

1780.
Journal:	Cancer Treat Rev. 2017 Nov;60:109-119.
Title:	Targeting BRAF in metastatic colorectal cancer: Maximizing molecular approaches.
Author:	Strickler, John H\|Wu, Christina\|Bekaii-Saab, Tanios
PMID:	28946014

1781.
Journal:	PLoS One. 2017 Sep 28;12(9):e0185607.
Title:	High mRNA expression of splice variant SYK short correlates with hepatic disease progression in chemonaive lymph node negative colon cancer patients.
Author:	Coebergh van den Braak, Robert R J\|Sieuwerts, Anieta M\|Kandimalla, Raju\|Lalmahomed, Zarina S\|Bril, Sandra I\|van Galen, Anne\|Smid, Marcel\|Biermann, Katharina\|van Krieken, J Han J M\|Kloosterman, Wigard P\|Foekens, John A\|Goel, Ajay\|Martens, John W M\|IJzerman
PMID:	28957395

1782.
Journal:	Biol Res. 2017 Oct 2;50(1):32.
Title:	Upregulation of lncRNA BANCR associated with the lymph node metastasis and poor prognosis in colorectal cancer.
Author:	Shen, Xiaogang\|Bai, Yifeng\|Luo, Bin\|Zhou, Xiaogang
PMID:	28969673

1783.
Journal:	Am J Cancer Res. 2017 Sep 1;7(9):1779-1787. eCollection 2017.
Title:	BANCR: a cancer-related long non-coding RNA.
Author:	Yu, Xin\|Zheng, Heyi\|Chan, Matthew Tv\|Wu, William Ka Kei
PMID:	28979803

1784.
Journal:	Oncotarget. 2017 Jun 20;8(39):65407-65413.
Title:	Colorectal carcinoma with osseous metaplasia.
Author:	Liu, Xibo\|Xu, Jinghong\|Chen, Lirong
PMID:	29029440

1785.
Journal:	Clin Lab. 2017 Oct 1;63(10):1731-1740.
Title:	Enhanced Specificity of BRAF V600E Genotyping Using Wild-Type Blocker Coupled with Internal Competitive Reference in a Single Tube.
Author:	Peng, Jia\|Wei, Kun\|Yu, Shu\|Yang, Xiang\|Zhao, Xiang\|Liu, Yu\|Zhu, Xiao-Yan\|Zhao, Na\|Huang, Qing\|Fu, Wei-Ling
PMID:	29035465

1786.
Journal:	Chin J Cancer. 2017 Oct 16;36(1):81.
Title:	Clinicopathologic features and treatment efficacy of Chinese patients with BRAF-mutated metastatic colorectal cancer: a retrospective observational study.
Author:	Wang, Xicheng\|Wei, Qing\|Gao, Jing\|Li, Jian\|Li, Jie\|Gong, Jifang\|Li, Yanyan\|Shen, Lin
PMID:	29037218

1787.
Journal:	Cancer Immunol Res. 2017 Nov;5(11):1046-1055.
Title:	Tumor PDCD1LG2 (PD-L2) Expression and the Lymphocytic Reaction to Colorectal Cancer.
Author:	Masugi, Yohei\|Nishihara, Reiko\|Hamada, Tsuyoshi\|Song, Mingyang\|da Silva, Annacarolina\|Kosumi, Keisuke\|Gu, Mancang\|Shi, Yan\|Li, Wanwan\|Liu, Li\|Nevo, Daniel\|Inamura, Kentaro\|Cao, Yin\|Liao, Xiaoyun\|Nosho, Katsuhiko\|Chan, Andrew T\|Giannakis, Marios\|Bass, Adam
PMID:	29038297

1788.
Journal:	Ann Oncol. 2017 Nov 1;28(11):2648-2657.
Title:	BRAF mutant colorectal cancer: prognosis, treatment, and new perspectives.
Author:	Sanz-Garcia, E\|Argiles, G\|Elez, E\|Tabernero, J
PMID:	29045527

1789.
Journal:	Clin Transl Gastroenterol. 2017 Oct 19;8(10):e124.
Title:	Increased Frequency of KRAS Mutations in African Americans Compared with Caucasians in Sporadic Colorectal Cancer.
Author:	Staudacher, Jonas J\|Yazici, Cemal\|Bul, Vadim\|Zeidan, Joseph\|Khalid, Ahmer\|Xia, Yinglin\|Krett, Nancy\|Jung, Barbara
PMID:	29048416

1790.
Journal:	Oncotarget. 2017 Jul 15;8(41):69756-69767.
Title:	Application of in vivo imaging techniques to monitor therapeutic efficiency of PLX4720 in an experimental model of microsatellite instable colorectal cancer.
Author:	Rohde, Sarah\|Lindner, Tobias\|Polei, Stefan\|Stenzel, Jan\|Borufka, Luise\|Achilles, Sophie\|Hartmann, Eric\|Lange, Falko\|Maletzki, Claudia\|Linnebacher, Michael\|Glass, Anne\|Schwarzenbock, Sarah Marie\|Kurth, Jens\|Hohn, Alexander\|Vollmar, Brigitte\|Krause, Bernd J
PMID:	29050239

1791.
Journal:	Oncotarget. 2017 Aug 21;8(42):72352-72362.
Title:	Acquired somatic TP53 or PIK3CA mutations are potential predictors of when polyps evolve into colorectal cancer.
Author:	Chang, Pi-Yueh\|Chen, Jinn-Shiun\|Chang, Shih-Cheng\|Wang, Mei-Chia\|Chang, Nai-Chung\|Wen, Ying-Hao\|Tsai, Wen-Sy\|Liu, Wei-Hsiu\|Liu, Hsiu-Ling\|Lu, Jang-Jih
PMID:	29069792

1792.
Journal:	Dtsch Med Wochenschr. 2017 Nov;142(22):1652-1659.
Title:	[Personalized Treatment for Colorectal Carcinomas].
Author:	Stintzing, Sebastian
PMID:	29078210

1793.
Journal:	J Pathol Clin Res. 2017 Oct 7;3(4):268-278.
Title:	Histopathological and genotypic characterization of metastatic colorectal carcinoma with PD-L1 (CD274)-expression: Possible roles of tumour micro environmental factors for CD274 expression.
Author:	Inaguma, Shingo\|Lasota, Jerzy\|Felisiak-Golabek, Anna\|Kowalik, Artur\|Wang, Zengfeng\|Zieba, Sebastian\|Kalisz, Joanna\|Ikeda, Hiroshi\|Miettinen, Markku
PMID:	29085667

1794.
Journal:	Ann Surg Treat Res. 2017 Oct;93(4):173-180.
Title:	Establishing a colorectal cancer liver metastasis patient-derived tumor xenograft model for the evaluation of personalized chemotherapy.
Author:	Jung, Joohee\|Kim, Jisup\|Lim, Hyun Kyung\|Kim, Kyoung Mee\|Lee, Yun Sun\|Park, Joon Seong\|Yoon, Dong Sup
PMID:	29094026

1795.
Journal:	Curr Probl Cancer. 2017 Nov - Dec;41(6):388-397.
Title:	Familial Colorectal Cancer Type X (FCCTX) and the correlation with various genes-A systematic review.
Author:	Nejadtaghi, Mahdieh\|Jafari, Hamideh\|Farrokhi, Effat\|Samani, Keihan Ghatreh
PMID:	29096939

1796.
Journal:	Oncotarget. 2017 May 26;8(44):77928-77941.
Title:	Meta-analysis of the mutational status of circulation tumor cells and paired primary tumor tissues from colorectal cancer patients.
Author:	Liu, Yong\|Meucci, Stefano\|Sheng, Liming\|Keilholz, Ulrich
PMID:	29100436

1797.
Journal:	Clin Chim Acta. 2017 Oct 27. pii: S0009-8981(17)30422-9.
Title:	Real-time PCR-based method for the rapid detection of extended RAS mutations using bridged nucleic acids in colorectal cancer.
Author:	Iida, Takao\|Mizuno, Yukie\|Kaizaki, Yasuharu
PMID:	29111094

1798.
Journal:	BMC Cancer. 2017 Nov 7;17(1):723.
Title:	microRNA-193a-3p is specifically down-regulated and acts as a tumor suppressor in BRAF-mutated colorectal cancer.
Author:	Takahashi, Hidekazu\|Takahashi, Masanobu\|Ohnuma, Shinobu\|Unno, Michiaki\|Yoshino, Yuki\|Ouchi, Kota\|Takahashi, Shin\|Yamada, Yasuhide\|Shimodaira, Hideki\|Ishioka, Chikashi
PMID:	29115941

1799.
Journal:	J Thorac Dis. 2017 Oct;9(Suppl 12):S1282-S1290.
Title:	Pulmonary metastasectomy for colorectal cancer: analysis of prognostic factors affecting survival.
Author:	Ampollini, Luca\|Gnetti, Letizia\|Goldoni, Matteo\|Viani, Lorenzo\|Faedda, Elisabetta\|Campanini, Nicoletta\|Caruana, Pietro\|Crafa, Pellegrino\|Negri, Francesca\|Pucci, Francesca\|Leonardi, Francesco\|Ventura, Luigi\|Balestra, Valeria\|Braggio, Cesare\|Bocchialini, Gi
PMID:	29119016

1800.
Journal:	Br J Cancer. 2017 Dec 5;117(12):1777-1786.
Title:	Nuclear IGF-1R predicts chemotherapy and targeted therapy resistance in metastatic colorectal cancer.
Author:	Codony-Servat, Jordi\|Cuatrecasas, Miriam\|Asensio, Elena\|Montironi, Carla\|Martinez-Cardus, Anna\|Marin-Aguilera, Mercedes\|Horndler, Carlos\|Martinez-Balibrea, Eva\|Rubini, Michele\|Jares, Pedro\|Reig, Oscar\|Victoria, Ivan\|Gaba, Lydia\|Martin-Richard, Marta\|Alons
PMID:	29123263

1801.
Journal:	Pathol Oncol Res. 2017 Nov 10. pii: 10.1007/s12253-017-0344-x.
Title:	Immunohistochemistry with Anti-BRAF V600E (VE1) Mouse Monoclonal Antibody is a Sensitive Method for Detection of the BRAF V600E Mutation in Colon Cancer: Evaluation of 120 Cases with and without KRAS Mutation and Literature Review.
Author:	Dvorak, Katerina\|Higgins, Amanda\|Palting, John\|Cohen, Michael\|Brunhoeber, Patrick
PMID:	29127628

1802.
Journal:	BMC Cancer. 2017 Nov 14;17(1):765.
Title:	Analysis of factors influencing molecular testing at diagnostic of colorectal cancer.
Author:	Thiebault, Quentin\|Defossez, Gautier\|Karayan-Tapon, Lucie\|Ingrand, Pierre\|Silvain, Christine\|Tougeron, David
PMID:	29137623

1803.
Journal:	Oncotarget. 2017 Sep 21;8(49):86356-86368.
Title:	Comparative molecular analyses of left-sided colon, right-sided colon, and rectal cancers.
Author:	Salem, Mohamed E\|Weinberg, Benjamin A\|Xiu, Joanne\|El-Deiry, Wafik S\|Hwang, Jimmy J\|Gatalica, Zoran\|Philip, Philip A\|Shields, Anthony F\|Lenz, Heinz-Josef\|Marshall, John L
PMID:	29156800

1804.
Journal:	BMC Gastroenterol. 2017 Nov 23;17(1):121.
Title:	Primary tumor location predicts poor clinical outcome with cetuximab in RAS wild-type metastatic colorectal cancer.
Author:	Kim, Dalyong\|Kim, Sun Young\|Lee, Ji Sung\|Hong, Yong Sang\|Kim, Jeong Eun\|Kim, Kyu-Pyo\|Kim, Jihun\|Jang, Se Jin\|Yoon, Young-Kwang\|Kim, Tae Won
PMID:	29169325

1805.
Journal:	Indian J Surg Oncol. 2017 Dec;8(4):580-590.
Title:	Molecular Landscape and Treatment Options for Patients with Metastatic Colorectal Cancer.
Author:	Miyamoto, Yuji\|Zhang, Wu\|Lenz, Heinz-Josef
PMID:	29203992

1806.
Journal:	ESMO Open. 2017 Aug 10;2(3):e000241.
Title:	Vinorelbine in BRAF V600E mutated metastatic colorectal cancer: a prospective multicentre phase II clinical study.
Author:	Cremolini, Chiara\|Pietrantonio, Filippo\|Tomasello, Gianluca\|Dadduzio, Vincenzo\|Moretto, Roberto\|Morano, Federica\|Schirripa, Marta\|Antoniotti, Carlotta\|Fuca, Giovanni\|Bergamo, Francesca\|Rossini, Daniele\|Nichetti, Federico\|Ziampiri, Stamatia\|Ghidini, Michel
PMID:	29209533

1807.
Journal:	Oncotarget. 2017 Aug 24;8(55):93567-93579.
Title:	Comprehensive genomic sequencing detects important genetic differences between right-sided and left-sided colorectal cancer.
Author:	Shimada, Yoshifumi\|Kameyama, Hitoshi\|Nagahashi, Masayuki\|Ichikawa, Hiroshi\|Muneoka, Yusuke\|Yagi, Ryoma\|Tajima, Yosuke\|Okamura, Takuma\|Nakano, Masato\|Sakata, Jun\|Kobayashi, Takashi\|Nogami, Hitoshi\|Maruyama, Satoshi\|Takii, Yasumasa\|Hayashida, Tetsu\|Takaishi
PMID:	29212173

1808.
Journal:	Hered Cancer Clin Pract. 2017 Nov 29;15:22.
Title:	Exome sequencing characterizes the somatic mutation spectrum of early serrated lesions in a patient with serrated polyposis syndrome (SPS).
Author:	Horpaopan, Sukanya\|Kirfel, Jutta\|Peters, Sophia\|Kloth, Michael\|Huneburg, Robert\|Altmuller, Janine\|Drichel, Dmitriy\|Odenthal, Margarete\|Kristiansen, Glen\|Strassburg, Christian\|Nattermann, Jacob\|Hoffmann, Per\|Nurnberg, Peter\|Buttner, Reinhard\|Thiele, Holger
PMID:	29213343

1809.
Journal:	Nat Commun. 2017 Dec 8;8(1):1998.
Title:	Robust RNA-based in situ mutation detection delineates colorectal cancer subclonal evolution.
Author:	Baker, Ann-Marie\|Huang, Weini\|Wang, Xiao-Ming Mindy\|Jansen, Marnix\|Ma, Xiao-Jun\|Kim, Jeffrey\|Anderson, Courtney M\|Wu, Xingyong\|Pan, Liuliu\|Su, Nan\|Luo, Yuling\|Domingo, Enric\|Heide, Timon\|Sottoriva, Andrea\|Lewis, Annabelle\|Beggs, Andrew D\|Wright, Nicholas
PMID:	29222441

1810.
Journal:	Klin Onkol. 2017 Winter;30(Supplementum3):62-65.
Title:	[Immunotherapy of Colorectal and Anal Carcinoma].
Author:	Tomasek, J\|Kiss, I
PMID:	29239195

1811.
Journal:	Oncotarget. 2017 Oct 19;8(61):103952-103967.
Title:	Bliss and Loewe interaction analyses of clinically relevant drug combinations in human colon cancer cell lines reveal complex patterns of synergy and antagonism.
Author:	Kashif, Muhammad\|Andersson, Claes\|Mansoori, Sharmineh\|Larsson, Rolf\|Nygren, Peter\|Gustafsson, Mats G
PMID:	29262612

1812.
Journal:	Appl Immunohistochem Mol Morphol. 2017 Dec 21.
Title:	BRAF V600E Mutation Across Multiple Tumor Types: Correlation Between DNA-based Sequencing and Mutation-specific Immunohistochemistry.
Author:	Loo, Eric\|Khalili, Parisa\|Beuhler, Karen\|Siddiqi, Imran\|Vasef, Mohammad A
PMID:	29271794

1813.
Journal:	Cell Rep. 2017 Dec 26;21(13):3833-3845.
Title:	Degree of Tissue Differentiation Dictates Susceptibility to BRAF-Driven Colorectal Cancer.
Author:	Tong, Kevin\|Pellon-Cardenas, Oscar\|Sirihorachai, Veerin R\|Warder, Bailey N\|Kothari, Om A\|Perekatt, Ansu O\|Fokas, Emily E\|Fullem, Robert L\|Zhou, Anbo\|Thackray, Joshua K\|Tran, Hiep\|Zhang, Lanjing\|Xing, Jinchuan\|Verzi, Michael P
PMID:	29281831

1814.
Journal:	Oncotarget. 2017 Sep 27;8(62):105072-105080.
Title:	Targeted next generation sequencing in Chinese colorectal cancer patients guided anti-EGFR treatment and facilitated precision cancer medicine.
Author:	Hou, Helei\|Liu, Dong\|Zhang, Chuantao\|Jiang, Yanxia\|Lu, Guifang\|Zhou, Na\|Yang, Xiaonan\|Zhang, Xiaoping\|Li, Zhuokun\|Zhu, Hongmei\|Qian, Zhaoyang\|Zhang, Xiaochun
PMID:	29285234

1815.
Journal:	J Natl Cancer Inst. 2017 Dec 1;109(12). pii: 3860155.
Title:	ALK, ROS1, and NTRK Rearrangements in Metastatic Colorectal Cancer.
Author:	Pietrantonio, Filippo\|Di Nicolantonio, Federica\|Schrock, Alexa B\|Lee, Jeeyun\|Tejpar, Sabine\|Sartore-Bianchi, Andrea\|Hechtman, Jaclyn F\|Christiansen, Jason\|Novara, Luca\|Tebbutt, Niall\|Fuca, Giovanni\|Antoniotti, Carlotta\|Kim, Seung Tae\|Murphy, Danielle\|Bere
PMID:	29370427

1816.
Journal:	High Throughput. 2017 Nov 6;6(4). pii: ht6040016.
Title:	A Computational Workflow Translates a 58-Gene Signature to a Formalin-Fixed, Paraffin-Embedded Sample-Based Companion Diagnostic for Personalized Treatment of the BRAF-Mutation-Like Subtype of Colorectal Cancers.
Author:	In 't Veld, Sjors G J G\|Duong, Kim N\|Snel, Mireille\|Witteveen, Anke\|Beumer, Ines J\|Delahaye, Leonie J M J\|Wehkamp, Diederik\|Bernards, Rene\|Glas, Annuska M\|Tian, Sun
PMID:	29479053

1817.
Journal:	Semin Oncol. 2017 Jul 4. pii: S0093-7754(17)30056-8.
Title:	Biomarker-driven and molecular targeted therapies for colorectal cancers.
Author:	Schirripa, Marta\|Cohen, Stacey A\|Battaglin, Francesca\|Lenz, Heinz-Josef
PMID:	30262397

1818.
Journal:	Appl Immunohistochem Mol Morphol. 2018 Feb;26(2):140-146.
Title:	The Role of SATB2 as a Diagnostic Marker of Sinonasal Intestinal-type Adenocarcinoma.
Author:	Skalova, Alena\|Sar, Aylin\|Laco, Jan\|Metelkova, Alena\|Miesbauerova, Marketa\|Steiner, Petr\|Svajdler, Marian\|Michal, Michal
PMID:	27258560

1819.
Journal:	Pathol Oncol Res. 2018 Jan;24(1):45-57.
Title:	Correlations of IGF-1R and COX-2 Expressions with Ras and BRAF Genetic Mutations, Clinicopathological Features and Prognosis of Colorectal Cancer Patients.
Author:	Jin, Mei\|Long, Zi-Wen\|Yang, Jing\|Lin, Xiang
PMID:	28188432

1820.
Journal:	Singapore Med J. 2018 Mar;59(3):139-143.
Title:	Extent of field change in colorectal cancers with BRAF mutation.
Author:	Poh, Aaron\|Chang, Heidi Sian Ying\|Tan, Kok Yang\|Sam, Xin Xiu\|Khoo, Avery\|Choo, Shoa Nian\|Nga, Min En\|Wan, Wei Keat
PMID:	28210747

1821.
Journal:	Curr Cancer Drug Targets. 2018;18(3):278-286.
Title:	Effects of PHA-665752 and Cetuximab Combination Treatment on In Vitro and Murine Xenograft Growth of Human Colorectal Cancer Cells with KRAS or BRAF Mutations.
Author:	Jia, Yi-Tao\|Yang, Dong-Hai\|Zhao, Zhaolong\|Bi, Xiao-Hui\|Han, Wei-Hua\|Feng, Bo\|Zhi, Jie\|Gu, Bin\|Duan, Zhihui\|Wu, Jian-Hua\|Ju, Ying-Chao\|Wang, Ming-Xia\|Li, Zhong-Xin
PMID:	28359236

1822.
Journal:	J Cell Physiol. 2018 Mar;233(3):2162-2169.
Title:	The therapeutic potential of targeting the BRAF mutation in patients with colorectal cancer.
Author:	Bahrami, Afsane\|Hesari, AmirReza\|Khazaei, Majid\|Hassanian, Seyed Mahdi\|Ferns, Gordon A\|Avan, Amir
PMID:	28407239

1823.
Journal:	Fam Cancer. 2018 Jan;17(1):63-69.
Title:	RNF43 is mutated less frequently in Lynch Syndrome compared with sporadic microsatellite unstable colorectal cancers.
Author:	Fennell, Lochlan J\|Clendenning, Mark\|McKeone, Diane M\|Jamieson, Saara H\|Balachandran, Samanthy\|Borowsky, Jennifer\|Liu, John\|Kawamata, Futoshi\|Bond, Catherine E\|Rosty, Christophe\|Burge, Matthew E\|Buchanan, Daniel D\|Leggett, Barbara A\|Whitehall, Vicki L J
PMID:	28573495

1824.
Journal:	Fam Cancer. 2018 Jan;17(1):79-86.
Title:	Constitutional mismatch repair deficiency and Lynch syndrome among consecutive Arab Bedouins with colorectal cancer in Israel.
Author:	Abu Freha, Naim\|Leibovici Weissman, Yaara\|Fich, Alexander\|Barnes Kedar, Inbal\|Halpern, Marisa\|Sztarkier, Ignacio\|Behar, Doron M\|Arbib Sneh, Orly\|Vilkin, Alex\|Baris, Hagit N\|Gingold, Rachel\|Lejbkowicz, Flavio\|Niv, Yaron\|Goldberg, Yael\|Levi, Zohar
PMID:	28608265

1825.
Journal:	Am J Surg Pathol. 2018 Feb;42(2):172-182.
Title:	Clinicopathologic and Molecular Characteristics of Synchronous Colorectal Carcinoma With Mismatch Repair Deficiency.
Author:	Nakano, Kayoko\|Yamamoto, Hidetaka\|Fujiwara, Minako\|Koga, Yutaka\|Tsuruta, Shinichi\|Ihara, Eikichi\|Oki, Eiji\|Nakamura, Masafumi\|Ogawa, Yoshihiro\|Oda, Yoshinao
PMID:	28877066

1826.
Journal:	J Clin Pathol. 2018 Apr;71(4):336-343.
Title:	Clinical performance evaluation of the Idylla NRAS-BRAF mutation test on retrospectively collected formalin-fixed paraffin-embedded colorectal cancer tissue.
Author:	Johnston, Louise\|Power, Michael\|Sloan, Philip\|Long, Anna\|Silmon, Angela\|Chaffey, Ben\|Lisgo, Andrea Jane\|Little, Liam\|Vercauteren, Ellen\|Steiniche, Torben\|Meyer, Tine\|Simpson, John
PMID:	28899979

1827.
Journal:	Int J Cancer. 2018 Jan 15;142(2):238-250.
Title:	Associations of alcohol intake, smoking, physical activity and obesity with survival following colorectal cancer diagnosis by stage, anatomic site and tumor molecular subtype.
Author:	Jayasekara, Harindra\|English, Dallas R\|Haydon, Andrew\|Hodge, Allison M\|Lynch, Brigid M\|Rosty, Christophe\|Williamson, Elizabeth J\|Clendenning, Mark\|Southey, Melissa C\|Jenkins, Mark A\|Room, Robin\|Hopper, John L\|Milne, Roger L\|Buchanan, Daniel D\|Giles, Graha
PMID:	28921583

1828.
Journal:	Mol Carcinog. 2018 Jan;57(1):114-124.
Title:	Early genetic aberrations in patients with sporadic colorectal cancer.
Author:	Druliner, Brooke R\|Ruan, Xiaoyang\|Sicotte, Hugues\|O'Brien, Daniel\|Liu, Hongfang\|Kocher, Jean-Pierre A\|Boardman, Lisa
PMID:	28926134

1829.
Journal:	Mod Pathol. 2018 Feb;31(2):343-349.
Title:	Optimal detection of clinically relevant mutations in colorectal carcinoma: sample pooling overcomes intra-tumoral heterogeneity.
Author:	Nelson, Andrew C\|Boone, Jamie\|Cartwright, David\|Thyagarajan, Bharat\|Kincaid, Robyn\|Lambert, Aaron P\|Karnuth, Kylene\|Henzler, Christine\|Yohe, Sophia
PMID:	29027537

1830.
Journal:	Mod Pathol. 2018 Mar;31(3):517-526.
Title:	Association between clinicopathological characteristics and RAS mutation in colorectal cancer.
Author:	Rimbert, Johan\|Tachon, Gaelle\|Junca, Audelaure\|Villalva, Claire\|Karayan-Tapon, Lucie\|Tougeron, David
PMID:	29052598

1831.
Journal:	Oncogene. 2018 Feb 22;37(8):1031-1040.
Title:	MLK3 phosphorylation by ERK1/2 is required for oxidative stress-induced invasion of colorectal cancer cells.
Author:	Schroyer, A L\|Stimes, N W\|Abi Saab, W F\|Chadee, D N
PMID:	29084209

1832.
Journal:	Clin Colorectal Cancer. 2018 Mar;17(1):73-79.
Title:	Molecular Profiling of Patients With Advanced Colorectal Cancer: Princess Margaret Cancer Centre Experience.
Author:	Chiu, Joanne W\|Krzyzanowska, Monika K\|Serra, Stefano\|Knox, Jennifer J\|Dhani, Neesha C\|Mackay, Helen\|Hedley, David\|Moore, Malcolm\|Liu, Geoffrey\|Burkes, Ronald L\|Brezden-Masley, Christine\|Roehrl, Michael H\|Craddock, Kenneth J\|Tsao, Ming-Sound\|Zhang, Tong\|Yu
PMID:	29128266

1833.
Journal:	Fam Cancer. 2018 Jul;17(3):395-402.
Title:	Universal determination of microsatellite instability using BAT26 as a single marker in an Argentine colorectal cancer cohort.
Author:	Gonzalez, Maria Laura\|Causada-Calo, Natalia\|Santino, Juan Pablo\|Dominguez-Valentin, Mev\|Ferro, Fabiana Alejandra\|Sammartino, Ines\|Kalfayan, Pablo German\|Verzura, Maria Alicia\|Pinero, Tamara Alejandra\|Cajal, Andrea Romina\|Pavicic, Walter\|Vaccaro, Carlos
PMID:	29128931

1834.
Journal:	Clin Colorectal Cancer. 2018 Mar;17(1):e69-e76.
Title:	Treatment and Survival Outcome of BRAF-Mutated Metastatic Colorectal Cancer: A Retrospective Matched Case-Control Study.
Author:	Kayhanian, Hamzeh\|Goode, Emily\|Sclafani, Francesco\|Ang, Joo Ern\|Gerlinger, Marco\|Gonzalez de Castro, David\|Shepherd, Scott\|Peckitt, Clare\|Rao, Sheela\|Watkins, David\|Chau, Ian\|Cunningham, David\|Starling, Naureen
PMID:	29129559

1835.
Journal:	Mol Cancer Ther. 2018 Apr;17(4):806-813.
Title:	Wnt/beta-Catenin Pathway Activation Mediates Adaptive Resistance to BRAF Inhibition in Colorectal Cancer.
Author:	Chen, Guangming\|Gao, Chenxi\|Gao, Xuan\|Zhang, Dennis Han\|Kuan, Shih-Fan\|Burns, Timothy F\|Hu, Jing
PMID:	29167314

1836.
Journal:	Clin Cancer Res. 2018 Mar 1;24(5):1062-1072.
Title:	Classifying Colorectal Cancer by Tumor Location Rather than Sidedness Highlights a Continuum in Mutation Profiles and Consensus Molecular Subtypes.
Author:	Loree, Jonathan M\|Pereira, Allan A L\|Lam, Michael\|Willauer, Alexandra N\|Raghav, Kanwal\|Dasari, Arvind\|Morris, Van K\|Advani, Shailesh\|Menter, David G\|Eng, Cathy\|Shaw, Kenna\|Broaddus, Russell\|Routbort, Mark J\|Liu, Yusha\|Morris, Jeffrey S\|Luthra, Rajyalakshm
PMID:	29180604

1837.
Journal:	Mol Oncol. 2018 Feb;12(2):224-238.
Title:	MAPK inhibitors induce serine peptidase inhibitor Kazal type 1 (SPINK1) secretion in BRAF V600E-mutant colorectal adenocarcinoma.
Author:	Rasanen, Kati\|Dang, Kien X\|Mustonen, Harri\|Ho, Tho H\|Lintula, Susanna\|Koistinen, Hannu\|Stenman, Ulf-Hakan\|Haglund, Caj\|Stenman, Jakob
PMID:	29193645

1838.
Journal:	Clin Colorectal Cancer. 2018 Mar;17(1):80-83.
Title:	Parallel Evaluation of Circulating Tumor DNA and Circulating Tumor Cells in Metastatic Colorectal Cancer.
Author:	Germano, Giovanni\|Mauri, Gianluca\|Siravegna, Giulia\|Dive, Caroline\|Pierce, Jackie\|Di Nicolantonio, Federica\|D'Incalci, Maurizio\|Bardelli, Alberto\|Siena, Salvatore\|Sartore-Bianchi, Andrea
PMID:	29195807

1839.
Journal:	Mol Cancer Res. 2018 Mar;16(3):486-495.
Title:	Proximal Aberrant Crypt Foci Associate with Synchronous Neoplasia and Are Primed for Neoplastic Progression.
Author:	Drew, David A\|Mo, Allen\|Grady, James J\|Stevens, Richard G\|Levine, Joel B\|Brenner, Bruce M\|Anderson, Joseph C\|Forouhar, Faripour\|O'Brien, Michael J\|Devers, Thomas J\|Rosenberg, Daniel W
PMID:	29222172

1840.
Journal:	Mol Carcinog. 2018 Mar;57(3):451-461.
Title:	Molecular profiling and genome-wide analysis based on somatic copy number alterations in advanced colorectal cancers.
Author:	Sugai, Tamotsu\|Takahashi, Yayoi\|Eizuka, Makoto\|Sugimoto, Ryo\|Fujita, Yasuko\|Habano, Wataru\|Otsuka, Kouki\|Sasaki, Akira\|Yamamoto, Eiichiro\|Matsumoto, Takayuki\|Suzuki, Hiromu
PMID:	29230882

1841.
Journal:	Mol Cancer Res. 2018 Mar;16(3):378-389.
Title:	Targeting CDK1 and MEK/ERK Overcomes Apoptotic Resistance in BRAF-Mutant Human Colorectal Cancer.
Author:	Zhang, Peng\|Kawakami, Hisato\|Liu, Weizhen\|Zeng, Xiangyu\|Strebhardt, Klaus\|Tao, Kaixiong\|Huang, Shengbing\|Sinicrope, Frank A
PMID:	29233910

1842.
Journal:	Epigenetics. 2018;13(1):40-48.
Title:	Oncogenic BRAF mutation induces DNA methylation changes in a murine model for human serrated colorectal neoplasia.
Author:	Bond, Catherine E\|Liu, Cheng\|Kawamata, Futoshi\|McKeone, Diane M\|Fernando, Winnie\|Jamieson, Saara\|Pearson, Sally-Ann\|Kane, Alexandra\|Woods, Susan L\|Lannagan, Tamsin R M\|Somashekar, Roshini\|Lee, Young\|Dumenil, Troy\|Hartel, Gunter\|Spring, Kevin J\|Borowsky, J
PMID:	29235923

1843.
Journal:	Am J Surg Pathol. 2018 Mar;42(3):351-358.
Title:	Site-specific Differences in Colonic Adenocarcinoma: KRAS Mutations and High Tumor Budding Are More Frequent in Cecal Adenocarcinoma.
Author:	Landau, Michael A\|Zhu, Benjamin\|Akwuole, Frances N\|Pai, Reetesh K
PMID:	29240583

1844.
Journal:	Lancet Gastroenterol Hepatol. 2018 Mar;3(3):162-171.
Title:	Inhibition of EGFR, HER2, and HER3 signalling in patients with colorectal cancer wild-type for BRAF, PIK3CA, KRAS, and NRAS (FOCUS4-D): a phase 2-3 randomised trial.
Author:	Adams, Richard\|Brown, Ewan\|Brown, Louise\|Butler, Rachel\|Falk, Stephen\|Fisher, David\|Kaplan, Richard\|Quirke, Phil\|Richman, Susan\|Samuel, Leslie\|Seligmann, Jenny\|Seymour, Matt\|Shiu, Kai Keen\|Wasan, Harpreet\|Wilson, Richard\|Maughan, Tim
PMID:	29254887

1845.
Journal:	Mol Cell Proteomics. 2018 Apr;17(4):550-564.
Title:	Specificity of Phosphorylation Responses to Mitogen Activated Protein (MAP) Kinase Pathway Inhibitors in Melanoma Cells.
Author:	Basken, Joel\|Stuart, Scott A\|Kavran, Andrew J\|Lee, Thomas\|Ebmeier, Christopher C\|Old, William M\|Ahn, Natalie G
PMID:	29255136

1846.
Journal:	Oncologist. 2018 Mar;23(3):277-e26.
Title:	Phase II Study of Panitumumab in RAS Wild-Type Metastatic Adenocarcinoma of Small Bowel or Ampulla of Vater.
Author:	Gulhati, Pat\|Raghav, Kanwal\|Shroff, Rachna\|Varadhachary, Gauri\|Javle, Milind\|Qiao, Wei\|Wang, Huamin\|Morris, Jeffrey\|Wolff, Robert\|Overman, Michael J
PMID:	29259073

1847.
Journal:
Title:	Cancer, Colon
Author:	Recio-Boiles, Alejandro\|Cagir, Burt
PMID:	29262132

1848.
Journal:	J Natl Cancer Inst. 2018 Jun 1;110(6):638-648.
Title:	Personalizing Survival Predictions in Advanced Colorectal Cancer: The ARCAD Nomogram Project.
Author:	Sjoquist, Katrin M\|Renfro, Lindsay A\|Simes, R John\|Tebbutt, Niall C\|Clarke, Stephen\|Seymour, Matthew T\|Adams, Richard\|Maughan, Timothy S\|Saltz, Leonard\|Goldberg, Richard M\|Schmoll, Hans-Joachim\|Van Cutsem, Eric\|Douillard, Jean-Yves\|Hoff, Paulo M\|Hecht, Jo
PMID:	29267900

1849.
Journal:	Mol Cancer Ther. 2018 Feb;17(2):544-553.
Title:	beta-Catenin mRNA Silencing and MEK Inhibition Display Synergistic Efficacy in Preclinical Tumor Models.
Author:	Ganesh, Shanthi\|Shui, Xue\|Craig, Kevin P\|Koser, Martin L\|Chopda, Girish R\|Cyr, Wendy A\|Lai, Chengjung\|Dudek, Henryk\|Wang, Weimin\|Brown, Bob D\|Abrams, Marc T
PMID:	29282298

1850.
Journal:	Mol Cancer Ther. 2018 Jan;17(1):3-16.
Title:	Rational Approaches for Combination Therapy Strategies Targeting the MAP Kinase Pathway in Solid Tumors.
Author:	Tolcher, Anthony W\|Peng, Wei\|Calvo, Emiliano
PMID:	29295962

1851.
Journal:	Genet Med. 2018 Jan 4. pii: gim2017244.
Title:	Which Lynch syndrome screening programs could be implemented in the "real world"? A systematic review of economic evaluations.
Author:	Di Marco, Marco\|D'Andrea, Elvira\|Panic, Nikola\|Baccolini, Valentina\|Migliara, Giuseppe\|Marzuillo, Carolina\|De Vito, Corrado\|Pastorino, Roberta\|Boccia, Stefania\|Villari, Paolo
PMID:	29300371

1852.
Journal:	Genome Med. 2018 Jan 4;10(1):2.
Title:	Linking FOXO3, NCOA3, and TCF7L2 to Ras pathway phenotypes through a genome-wide forward genetic screen in human colorectal cancer cells.
Author:	Kundu, Snehangshu\|Ali, Muhammad Akhtar\|Handin, Niklas\|Padhan, Narendra\|Larsson, Jimmy\|Karoutsou, Maria\|Ban, Kenneth\|Wisniewski, Jacek R\|Artursson, Per\|He, Liqun\|Hellstrom, Mats\|Sjoblom, Tobias
PMID:	29301589

1853.
Journal:	BMC Cancer. 2018 Jan 5;18(1):35.
Title:	MLH1-93 G/a polymorphism is associated with MLH1 promoter methylation and protein loss in dysplastic sessile serrated adenomas with BRAF(V600E) mutation.
Author:	Fennell, Lochlan J\|Jamieson, Saara\|McKeone, Diane\|Corish, Tracie\|Rohdmann, Megan\|Furner, Tori\|Bettington, Mark\|Liu, Cheng\|Kawamata, Futoshi\|Bond, Catherine\|Van De Pols, Jolieke\|Leggett, Barbara\|Whitehall, Vicki
PMID:	29304767

1854.
Journal:	Adv Clin Chem. 2018;83:53-72.
Title:	Locked Nucleic Acid Technology for Highly Sensitive Detection of Somatic Mutations in Cancer.
Author:	Ishige, Takayuki\|Itoga, Sakae\|Matsushita, Kazuyuki
PMID:	29304903

1855.
Journal:	Clin Gastroenterol Hepatol. 2018 Jan 3. pii: S1542-3565(17)31536-7.
Title:	Associations Between Molecular Classifications of Colorectal Cancer and Patient Survival: A Systematic Review.
Author:	Alwers, Elizabeth\|Jia, Min\|Kloor, Matthias\|Blaker, Hendrik\|Brenner, Hermann\|Hoffmeister, Michael
PMID:	29306042

1856.
Journal:	Hum Pathol. 2018 Apr;74:54-63.
Title:	Genomic heterogeneity in primary colorectal carcinomas and their metastases: born bad or brought up a villain?
Author:	Huhns, Maja\|Krohn, Saskia\|Murua Escobar, Hugo\|Prall, Friedrich
PMID:	29307628

1857.
Journal:	Cancer Cell. 2018 Jan 8;33(1):125-136.e3.
Title:	Clinical Sequencing Defines the Genomic Landscape of Metastatic Colorectal Cancer.
Author:	Yaeger, Rona\|Chatila, Walid K\|Lipsyc, Marla D\|Hechtman, Jaclyn F\|Cercek, Andrea\|Sanchez-Vega, Francisco\|Jayakumaran, Gowtham\|Middha, Sumit\|Zehir, Ahmet\|Donoghue, Mark T A\|You, Daoqi\|Viale, Agnes\|Kemeny, Nancy\|Segal, Neil H\|Stadler, Zsofia K\|Varghese, Anna
PMID:	29316426

1858.
Journal:	Cancer Metastasis Rev. 2018 Mar;37(1):173-187.
Title:	Mutations of key driver genes in colorectal cancer progression and metastasis.
Author:	Huang, Dongdong\|Sun, Wenjie\|Zhou, Yuwei\|Li, Peiwei\|Chen, Fang\|Chen, Hanwen\|Xia, Dajing\|Xu, Enping\|Lai, Maode\|Wu, Yihua\|Zhang, Honghe
PMID:	29322354

1859.
Journal:	Oncogene. 2018 Mar;37(12):1576-1593.
Title:	BRAF inhibition upregulates a variety of receptor tyrosine kinases and their downstream effector Gab2 in colorectal cancer cell lines.
Author:	Herr, Ricarda\|Halbach, Sebastian\|Heizmann, Miriam\|Busch, Hauke\|Boerries, Melanie\|Brummer, Tilman
PMID:	29326440

1860.
Journal:	Eur Radiol. 2018 May;28(5):2058-2067.
Title:	Can CT-based radiomics signature predict KRAS/NRAS/BRAF mutations in colorectal cancer?
Author:	Yang, Lei\|Dong, Di\|Fang, Mengjie\|Zhu, Yongbei\|Zang, Yali\|Liu, Zhenyu\|Zhang, Hongmei\|Ying, Jianming\|Zhao, Xinming\|Tian, Jie
PMID:	29335867

1861.
Journal:	Br J Cancer. 2018 Mar 6;118(5):705-712.
Title:	The relationship between right-sided tumour location, tumour microenvironment, systemic inflammation, adjuvant therapy and survival in patients undergoing surgery for colon and rectal cancer.
Author:	Patel, Meera\|McSorley, Stephen T\|Park, James H\|Roxburgh, Campbell S D\|Edwards, Joann\|Horgan, Paul G\|McMillan, Donald C
PMID:	29337962

1862.
Journal:	Cancer Med. 2018 Feb;7(2):433-444.
Title:	Contribution of MLH1 constitutional methylation for Lynch syndrome diagnosis in patients with tumor MLH1 downregulation.
Author:	Pinto, Diana\|Pinto, Carla\|Guerra, Joana\|Pinheiro, Manuela\|Santos, Rui\|Vedeld, Hege Marie\|Yohannes, Zeremariam\|Peixoto, Ana\|Santos, Catarina\|Pinto, Pedro\|Lopes, Paula\|Lothe, Ragnhild\|Lind, Guro Elisabeth\|Henrique, Rui\|Teixeira, Manuel R
PMID:	29341452

1863.
Journal:	Future Oncol. 2018 Jun;14(14):1355-1364.
Title:	The clinicopathological features and prognosis of tumor MSI in East Asian colorectal cancer patients using NCI panel.
Author:	Zheng, Jianmin\|Huang, Bangxing\|Nie, Xiu\|Zhu, Yan\|Han, Ningning\|Li, Yan
PMID:	29366338

1864.
Journal:	Transl Oncol. 2018 Apr;11(2):213-220.
Title:	Significance of Liquid Biopsy for Monitoring and Therapy Decision of Colorectal Cancer.
Author:	Klein-Scory, Susanne\|Maslova, Marina\|Pohl, Michael\|Eilert-Micus, Christina\|Schroers, Roland\|Schmiegel, Wolff\|Baraniskin, Alexander
PMID:	29367069

1865.
Journal:	Anticancer Res. 2018 Feb;38(2):677-683.
Title:	MicroRNA Expression in KRAS- and BRAF-mutated Colorectal Cancers.
Author:	Lundberg, Ida V\|Wikberg, Maria L\|Ljuslinder, Ingrid\|Li, Xingru\|Myte, Robin\|Zingmark, Carl\|Lofgren-Burstrom, Anna\|Edin, Sofia\|Palmqvist, Richard
PMID:	29374690

1866.
Journal:	Acta Oncol. 2018 Aug;57(8):1057-1062.
Title:	Associations between primary tumor RAS, BRAF and PIK3CA mutation status and metastatic site in patients with chemo-resistant metastatic colorectal cancer.
Author:	Christensen, Troels Dreier\|Palshof, Jesper Andreas\|Larsen, Finn Ole\|Poulsen, Tim Svenstrup\|Hogdall, Estrid\|Pfeiffer, Per\|Jensen, Benny Vittrup\|Yilmaz, Mette Karen\|Nielsen, Dorte
PMID:	29380640

1867.
Journal:	Gut. 2018 Jan 30. pii: gutjnl-2017-315664.
Title:	Lymphocytic response to tumour and deficient DNA mismatch repair identify subtypes of stage II/III colorectal cancer associated with patient outcomes.
Author:	Williams, David S\|Mouradov, Dmitri\|Jorissen, Robert N\|Newman, Marsali R\|Amini, Elham\|Nickless, David K\|Teague, Julie A\|Fang, Catherine G\|Palmieri, Michelle\|Parsons, Marie J\|Sakthianandeswaren, Anuratha\|Li, Shan\|Ward, Robyn L\|Hawkins, Nicholas J\|Faragher,
PMID:	29382774

1868.
Journal:	ESMO Open. 2018 Jan 10;3(1):e000299.
Title:	Sequential HER2 blockade as effective therapy in chemorefractory, HER2 gene-amplified, RAS wild-type, metastatic colorectal cancer: learning from a clinical case.
Author:	Martinelli, Erika\|Troiani, Teresa\|Sforza, Vincenzo\|Martini, Giulia\|Cardone, Claudia\|Vitiello, Pietro Paolo\|Ciardiello, Davide\|Rachiglio, Anna Maria\|Normanno, Nicola\|Sartore-Bianchi, Andrea\|Marsoni, Silvia\|Bardelli, Alberto\|Siena, Salvatore\|Ciardiello, For
PMID:	29387480

1869.
Journal:	J Gastrointest Cancer. 2018 Feb 1. pii: 10.1007/s12029-018-0062-y.
Title:	Clinical Impact of PI3K/BRAF Mutations in RAS Wild Metastatic Colorectal Cancer: Meta-analysis Results.
Author:	Mohamed, Amr\|Twardy, Brandon\|AbdAllah, Nadine\|Akhras, Alaa\|Ismail, Hibah\|Zordok, Magdi\|Schrapp, Kelly\|Attumi, Taraq\|Tesfaye, Anteneh\|El-Rayes, Bassel
PMID:	29388061

1870.
Journal:	BMC Cancer. 2018 Feb 6;18(1):155.
Title:	Association of rs2282679 A>C polymorphism in vitamin D binding protein gene with colorectal cancer risk and survival: effect modification by dietary vitamin D intake.
Author:	Zhu, Yun\|Wang, Peizhong Peter\|Zhai, Guangju\|Bapat, Bharati\|Savas, Sevtap\|Woodrow, Jennifer R\|Campbell, Peter T\|Li, Yuming\|Yang, Ning\|Zhou, Xin\|Dicks, Elizabeth\|Mclaughlin, John R\|Parfrey, Patrick S
PMID:	29409465

1871.
Journal:	Hum Pathol. 2018 Apr;74:178-182.
Title:	KRAS and 2 rare PI3KCA mutations coexisting in a metastatic colorectal cancer patient with aggressive and resistant disease.
Author:	Tessitore, Alessandra\|Bruera, Gemma\|Mastroiaco, Valentina\|Cannita, Katia\|Cortellini, Alessio\|Cocciolone, Valentina\|Dal Mas, Antonella\|Calvisi, Giuseppe\|Zazzeroni, Francesca\|Ficorella, Corrado\|Ricevuto, Enrico\|Alesse, Edoardo
PMID:	29409955

1872.
Journal:	Pathobiology. 2018;85(1-2):72-84.
Title:	Tumor Heterogeneity in Colorectal Cancer: What Do We Know So Far?
Author:	Sagaert, Xavier\|Vanstapel, Arno\|Verbeek, Sanne
PMID:	29414818

1873.
Journal:	Oncoimmunology. 2017 Dec 18;7(2):e1378844.
Title:	Maturation of tertiary lymphoid structures and recurrence of stage II and III colorectal cancer.
Author:	Posch, Florian\|Silina, Karina\|Leibl, Sebastian\|Mundlein, Axel\|Moch, Holger\|Siebenhuner, Alexander\|Samaras, Panagiotis\|Riedl, Jakob\|Stotz, Michael\|Szkandera, Joanna\|Stoger, Herbert\|Pichler, Martin\|Stupp, Roger\|van den Broek, Maries\|Schraml, Peter\|Gerger, A
PMID:	29416939

1874.
Journal:	Cancer Discov. 2018 Apr;8(4):417-427.
Title:	Convergent Therapeutic Strategies to Overcome the Heterogeneity of Acquired Resistance in BRAF(V600E) Colorectal Cancer.
Author:	Hazar-Rethinam, Mehlika\|Kleyman, Marianna\|Han, G Celine\|Liu, David\|Ahronian, Leanne G\|Shahzade, Heather A\|Chen, Lifeng\|Parikh, Aparna R\|Allen, Jill N\|Clark, Jeffrey W\|Kwak, Eunice L\|Faris, Jason E\|Murphy, Janet E\|Hong, Theodore S\|Van Seventer, Emily E\|Nad
PMID:	29431697

1875.
Journal:	Cancer Discov. 2018 Apr;8(4):428-443.
Title:	Combined BRAF, EGFR, and MEK Inhibition in Patients with BRAF(V600E)-Mutant Colorectal Cancer.
Author:	Corcoran, Ryan B\|Andre, Thierry\|Atreya, Chloe E\|Schellens, Jan H M\|Yoshino, Takayuki\|Bendell, Johanna C\|Hollebecque, Antoine\|McRee, Autumn J\|Siena, Salvatore\|Middleton, Gary\|Muro, Kei\|Gordon, Michael S\|Tabernero, Josep\|Yaeger, Rona\|O'Dwyer, Peter J\|Humble
PMID:	29431699

1876.
Journal:	Oncotarget. 2017 Dec 20;9(4):4707-4721.
Title:	Epigenetic silencing of SMOC1 in traditional serrated adenoma and colorectal cancer.
Author:	Aoki, Hironori\|Yamamoto, Eiichiro\|Takasawa, Akira\|Niinuma, Takeshi\|Yamano, Hiro-O\|Harada, Taku\|Matsushita, Hiro-O\|Yoshikawa, Kenjiro\|Takagi, Ryo\|Harada, Eiji\|Tanaka, Yoshihito\|Yoshida, Yuko\|Aoyama, Tomoyuki\|Eizuka, Makoto\|Yorozu, Akira\|Kitajima, Hiroshi\|K
PMID:	29435136

1877.
Journal:	Gut. 2018 Mar;67(3):447-455.
Title:	Double somatic mutations in mismatch repair genes are frequent in colorectal cancer after Hodgkin's lymphoma treatment.
Author:	Rigter, Lisanne S\|Snaebjornsson, Petur\|Rosenberg, Efraim H\|Atmodimedjo, Peggy N\|Aleman, Berthe M\|Ten Hoeve, Jelle\|Geurts-Giele, Willemina R\|van Ravesteyn, Thomas W\|Hoeksel, Johan\|Meijer, Gerrit A\|Te Riele, Hein\|van Leeuwen, Flora E\|Dinjens, Winand N\|van L
PMID:	29439113

1878.
Journal:	Oncol Lett. 2018 Mar;15(3):3904-3910.
Title:	Effects of PHA-665752 and vemurafenib combination treatment on in vitro and murine xenograft growth of human colorectal cancer cells with BRAF(V600E) mutations.
Author:	Zhi, Jie\|Li, Zhongxin\|Lv, Jian\|Feng, Bo\|Yang, Donghai\|Xue, Liang\|Zhao, Zhaolong\|Zhang, Yanni\|Wu, Jianhua\|Jv, Yingchao\|Jia, Yitao
PMID:	29456739

1879.
Journal:	Clin Drug Investig. 2018 Jun;38(6):553-562.
Title:	First-Line Cetuximab Monotherapy in KRAS/NRAS/BRAF Mutation-Negative Colorectal Cancer Patients.
Author:	Moiseyenko, Vladimir M\|Moiseyenko, Fedor V\|Yanus, Grigoriy A\|Kuligina, Ekatherina Sh\|Sokolenko, Anna P\|Bizin, Ilya V\|Kudriavtsev, Alexey A\|Aleksakhina, Svetlana N\|Volkov, Nikita M\|Chubenko, Vyacheslav A\|Kozyreva, Kseniya S\|Kramchaninov, Mikhail M\|Zhuravle
PMID:	29470838

1880.
Journal:	Mol Cancer Ther. 2018 Jun;17(6):1280-1290.
Title:	The Unfolded Protein Response: A Novel Therapeutic Target for Poor Prognostic BRAF Mutant Colorectal Cancer.
Author:	Forsythe, Nicholas\|Refaat, Alaa\|Javadi, Arman\|Khawaja, Hajrah\|Weir, Jessica-Anne\|Emam, Heba\|Allen, Wendy L\|Burkamp, Frank\|Popovici, Vlad\|Jithesh, Puthen V\|Isella, Claudio\|Labonte, Melissa J\|Mills, Ian G\|Johnston, Patrick G\|Van Schaeybroeck, Sandra
PMID:	29483217

1881.
Journal:	Surg Oncol Clin N Am. 2018 Apr;27(2):235-242.
Title:	Systemic Therapy for Colon Cancer.
Author:	Wu, Christina
PMID:	29496087

1882.
Journal:	Surg Oncol Clin N Am. 2018 Apr;27(2):349-365.
Title:	Clinical Trials and Progress in Metastatic Colon Cancer.
Author:	Mody, Kabir\|Bekaii-Saab, Tanios
PMID:	29496094

1883.
Journal:	United European Gastroenterol J. 2018 Mar;6(2):290-299.
Title:	Genetic Biopsy for Prediction of Surveillance Intervals after Endoscopic Resection of Colonic Polyps: Results of the GENESIS Study.
Author:	Berger, Andreas W\|Raedler, Katja\|Langner, Cord\|Ludwig, Leopold\|Dikopoulos, Nektarios\|Becker, Karl F\|Slotta-Huspenina, Julia\|Quante, Michael\|Schwerdel, Daniel\|Perkhofer, Lukas\|Kleger, Alexander\|Zizer, Eugen\|Oswald, Franz\|Seufferlein, Thomas\|Meining, Alexan
PMID:	29511559

1884.
Journal:	Ann Oncol. 2018 May 1;29(5):1227-1234.
Title:	CMS-dependent prognostic impact of KRAS and BRAFV600E mutations in primary colorectal cancer.
Author:	Smeby, J\|Sveen, A\|Merok, M A\|Danielsen, S A\|Eilertsen, I A\|Guren, M G\|Dienstmann, R\|Nesbakken, A\|Lothe, R A
PMID:	29518181

1885.
Journal:	Oncologist. 2018 Aug;23(8):912-918.
Title:	Phase II Study of Preoperative Treatment with External Radiotherapy Plus Panitumumab in Low-Risk, Locally Advanced Rectal Cancer (RaP Study/STAR-03).
Author:	Pinto, Carmine\|Di Bisceglie, Maurizio\|Di Fabio, Francesca\|Bochicchio, Annamaria\|Latiano, Tiziana\|Cordio, Stefano\|Rosati, Gerardo\|Aschele, Carlo\|Marino, Antonella\|Bergamo, Francesca\|Bustreo, Sara\|Frassineti, Luca\|Ciardiello, Fortunato\|Damato, Angela\|Giaqui
PMID:	29523646

1886.
Journal:	Clin Colorectal Cancer. 2018 Jun;17(2):e331-e352.
Title:	Phosphorylation of p70 Ribosomal Protein S6 Kinase beta-1 is an Independent Prognostic Parameter in Metastatic Colorectal Cancer.
Author:	Wiesweg, Marcel\|Reis, Henning\|Koster, Tobias\|Goetz, Moritz\|Worm, Karl\|Herold, Thomas\|Paul, Andreas\|Dechene, Alexander\|Schumacher, Brigitte\|Markus, Peter\|Virchow, Isabel\|Kostbade, Karina\|Wolf, Nathalie\|Zaun, Gregor\|Metzenmacher, Martin\|Schmid, Kurt W\|Schul
PMID:	29526493

1887.
Journal:	ESMO Open. 2018 Feb 24;3(2):e000297.
Title:	Exploratory pooled analysis evaluating the effect of sequence of biological therapies on overall survival in patients with RAS wild-type metastatic colorectal carcinoma.
Author:	Peeters, Marc\|Forget, Frederic\|Karthaus, Meinolf\|Valladares-Ayerbes, Manuel\|Zaniboni, Alberto\|Demonty, Gaston\|Guan, Xuesong\|Rivera, Fernando
PMID:	29531837

1888.
Journal:	Adv Biomed Res. 2018 Feb 16;7:28.
Title:	Clinical Aspects of Microsatellite Instability Testing in Colorectal Cancer.
Author:	Zeinalian, Mehrdad\|Hashemzadeh-Chaleshtori, Morteza\|Salehi, Rasoul\|Emami, Mohammad Hassan
PMID:	29531926

1889.
Journal:	Acta Biochim Biophys Sin (Shanghai). 2018 Apr 1;50(4):355-361.
Title:	BRAF and EGFR inhibitors synergize to increase cytotoxic effects and decrease stem cell capacities in BRAF(V600E)-mutant colorectal cancer cells.
Author:	Wu, Zhenhua\|Huang, Mingzhu\|Gong, Yiwei\|Lin, Chen\|Guo, Weijian
PMID:	29534162

1890.
Journal:	Ann Oncol. 2018 Jun 1;29(6):1394-1401.
Title:	RET fusions in a small subset of advanced colorectal cancers at risk of being neglected.
Author:	Pietrantonio, F\|Di Nicolantonio, F\|Schrock, A B\|Lee, J\|Morano, F\|Fuca, G\|Nikolinakos, P\|Drilon, A\|Hechtman, J F\|Christiansen, J\|Gowen, K\|Frampton, G M\|Gasparini, P\|Rossini, D\|Gigliotti, C\|Kim, S T\|Prisciandaro, M\|Hodgson, J\|Zaniboni, A\|Chiu, V K\|Milione,
PMID:	29538669

1891.
Journal:	Oncogene. 2018 Jun;37(24):3183-3199.
Title:	Classifying BRAF alterations in cancer: new rational therapeutic strategies for actionable mutations.
Author:	Dankner, Matthew\|Rose, April A N\|Rajkumar, Shivshankari\|Siegel, Peter M\|Watson, Ian R
PMID:	29540830

1892.
Journal:	Am J Med Sci. 2018 Mar;355(3):220-227.
Title:	Use of Liquid Biopsy in Monitoring Colorectal Cancer Progression Shows Strong Clinical Correlation.
Author:	Sun, Qiushi\|Liu, Yuan\|Liu, Bo\|Liu, Yingying
PMID:	29549923

1893.
Journal:	Theranostics. 2018 Feb 12;8(6):1678-1689.
Title:	Surface Enhanced Raman Spectroscopy (SERS) for the Multiplex Detection of Braf, Kras, and Pik3ca Mutations in Plasma of Colorectal Cancer Patients.
Author:	Li, Xiaozhou\|Yang, Tianyue\|Li, Caesar Siqi\|Song, Youtao\|Lou, Hong\|Guan, Dagang\|Jin, Lili
PMID:	29556349

1894.
Journal:	Cancer Manag Res. 2018 Mar 6;10:425-437.
Title:	Evolution of regorafenib from bench to bedside in colorectal cancer: Is it an attractive option or merely a "me too" drug?
Author:	Goel, Gaurav
PMID:	29563833

1895.
Journal:	Gastroenterol Hepatol Bed Bench. 2018 Winter;11(1):34-41.
Title:	Extracted metabolite from Streptomyces Levis ABRIINW111 altered the gene expression in colon cancer.
Author:	Fatourachi, Parisa\|Faramarziyan Azimi Maragheh, Behnaz\|Mohammadi, Seyede Momeneh\|Valipour, Behnaz\|Dehnad, Alireza\|Nozad Charoudeh, Hojjatollah
PMID:	29564063

1896.
Journal:	Oncotarget. 2018 Feb 13;9(17):13834-13847.
Title:	Bcl-xL as a poor prognostic biomarker and predictor of response to adjuvant chemotherapy specifically in BRAF-mutant stage II and III colon cancer.
Author:	Dunne, Philip D\|Coleman, Helen G\|Bankhead, Peter\|Alderdice, Matthew\|Gray, Ronan T\|McQuaid, Stephen\|Bingham, Victoria\|Loughrey, Maurice B\|James, Jacqueline A\|McCorry, Amy M B\|Gilmore, Alan\|Holohan, Caitriona\|Klingbiel, Dirk\|Tejpar, Sabine\|Johnston, Patrick
PMID:	29568398

1897.
Journal:	Int J Oncol. 2018 Mar 20.
Title:	Polo-like kinase 2 promotes chemoresistance and predicts limited survival benefit from adjuvant chemotherapy in colorectal cancer.
Author:	Xie, Yuquan\|Liu, Ying\|Li, Qiubo\|Chen, Jianming
PMID:	29568868

1898.
Journal:	J Clin Gastroenterol. 2018 Mar 21.
Title:	Sessile Serrated Adenomas in Young Patients may have Limited Risk of Malignant Progression.
Author:	Bettington, Mark\|Brown, Ian\|Rosty, Christophe\|Walker, Neal\|Liu, Cheng\|Croese, John\|Rahman, Tony\|Pearson, Sally-Ann\|McKeone, Diane\|Leggett, Barbara\|Whitehall, Vicki
PMID:	29570172

1899.
Journal:	Clin Cancer Res. 2018 Aug 1;24(15):3550-3559.
Title:	Exome Sequencing of Plasma DNA Portrays the Mutation Landscape of Colorectal Cancer and Discovers Mutated VEGFR2 Receptors as Modulators of Antiangiogenic Therapies.
Author:	Toledo, Rodrigo A\|Garralda, Elena\|Mitsi, Maria\|Pons, Tirso\|Monsech, Jorge\|Vega, Estela\|Otero, Alvaro\|Albarran, Maria I\|Banos, Natalia\|Duran, Yolanda\|Bonilla, Victoria\|Sarno, Francesca\|Camacho-Artacho, Marta\|Sanchez-Perez, Tania\|Perea, Sofia\|Alvarez, Rafae
PMID:	29588308

1900.
Journal:	Methods Mol Biol. 2018;1765:281-297.
Title:	Molecular Testing for the Treatment of Advanced Colorectal Cancer: An Overview.
Author:	Lin, Patrick S\|Semrad, Thomas J
PMID:	29589315

1901.
Journal:	J Pathol Transl Med. 2018 May;52(3):157-163.
Title:	Utility of BRAF VE1 Immunohistochemistry as a Screening Tool for Colorectal Cancer Harboring BRAF V600E Mutation.
Author:	Kwon, Jeong-Hwa\|Jeong, Byung-Kwan\|Yoon, Yong Sik\|Yu, Chang Sik\|Kim, Jihun
PMID:	29590746

1902.
Journal:	JAMA Oncol. 2018 Jun 1;4(6):806-813.
Title:	Assessment of Tumor Sequencing as a Replacement for Lynch Syndrome Screening and Current Molecular Tests for Patients With Colorectal Cancer.
Author:	Hampel, Heather\|Pearlman, Rachel\|Beightol, Mallory\|Zhao, Weiqiang\|Jones, Daniel\|Frankel, Wendy L\|Goodfellow, Paul J\|Yilmaz, Ahmet\|Miller, Kristin\|Bacher, Jason\|Jacobson, Angela\|Paskett, Electra\|Shields, Peter G\|Goldberg, Richard M\|de la Chapelle, Albert\|S
PMID:	29596542

1903.
Journal:	Anticancer Res. 2018 Apr;38(4):2235-2240.
Title:	Racial Disparities in the Molecular Landscape of Cancer.
Author:	Heath, Elisabeth I\|Lynce, Filipa\|Xiu, Joanne\|Ellerbrock, Angela\|Reddy, Sandeep K\|Obeid, Elias\|Liu, Stephen V\|Bollig-Fischer, Aliccia\|Separovic, Duska\|Vanderwalde, Ari
PMID:	29599344

1904.
Journal:	Mol Cancer Ther. 2018 Apr;17(4):719-723.
Title:	Adaptive Resistance to Chemotherapy, A Multi-FAK-torial Linkage.
Author:	Taylor, Kristin N\|Schlaepfer, David D
PMID:	29610281

1905.
Journal:	Cancer Discov. 2018 Apr;8(4):389-391.
Title:	Advances on the BRAF Front in Colorectal Cancer.
Author:	Janku, Filip
PMID:	29610287

1906.
Journal:	Evid Based Complement Alternat Med. 2018 Feb 12;2018:6517034.
Title:	A Network Pharmacology Approach to Uncover the Multiple Mechanisms of Hedyotis diffusa Willd. on Colorectal Cancer.
Author:	Liu, Xinkui\|Wu, Jiarui\|Zhang, Dan\|Wang, Kaihuan\|Duan, Xiaojiao\|Zhang, Xiaomeng
PMID:	29619072

1907.
Journal:	Gastrointest Cancer. 2018;8:13-23.
Title:	Emerging treatment options for BRAF-mutant colorectal cancer.
Author:	Ursem, Carling\|Atreya, Chloe E\|Van Loon, Katherine
PMID:	29628780

1908.
Journal:	Cesk Patol. 2018 Spring;54(1):17-21.
Title:	[Prediction of EGFR blockade responses in metastatic colorectal carcinoma].
Author:	Fabian, Pavel\|Nemecek, Radim
PMID:	29631407

1909.
Journal:	J Natl Compr Canc Netw. 2018 Apr;16(4):359-369.
Title:	NCCN Guidelines Insights: Colon Cancer, Version 2.2018.
Author:	Benson, Al B 3rd\|Venook, Alan P\|Al-Hawary, Mahmoud M\|Cederquist, Lynette\|Chen, Yi-Jen\|Ciombor, Kristen K\|Cohen, Stacey\|Cooper, Harry S\|Deming, Dustin\|Engstrom, Paul F\|Garrido-Laguna, Ignacio\|Grem, Jean L\|Grothey, Axel\|Hochster, Howard S\|Hoffe, Sarah\|Hunt,
PMID:	29632055

1910.
Journal:	Oncotarget. 2018 Feb 15;9(20):15302-15311.
Title:	Differential clinicopathological and molecular features within late-onset colorectal cancer according to tumor location.
Author:	Brandariz, Lorena\|Arriba, Maria\|Garcia, Juan Luis\|Cano, Juana Maria\|Rueda, Daniel\|Rubio, Eduardo\|Rodriguez, Yolanda\|Perez, Jessica\|Vivas, Alfredo\|Sanchez, Carmen\|Tapial, Sandra\|Pena, Laura\|Garcia-Arranz, Mariano\|Garcia-Olmo, Damian\|Urioste, Miguel\|Gonzale
PMID:	29632645

1911.
Journal:	Z Gastroenterol. 2018 Apr;56(4):384-397.
Title:	[ASCO- and ESMO-update 2017 - highlights of the 53. meeting of the American Society of Clinical Oncology/ASCO 2017 and European Society for Medical Oncology/ESMO congress 2017].
Author:	Ettrich, Thomas J\|Ebert, Matthias\|Lorenzen, Sylvie\|Moehler, Markus\|Vogel, Arndt\|Witkowski, Lukas\|Seufferlein, Thomas\|Reinacher-Schick, Anke
PMID:	29642252

1912.
Journal:	Gastroenterol Res Pract. 2018 Jan 31;2018:4585802.
Title:	Predictive and Prognostic Implications of Mutation Profiling and Microsatellite Instability Status in Patients with Metastatic Colorectal Carcinoma.
Author:	Liu, Jianhua\|Zeng, Weiqiang\|Huang, Chengzhi\|Wang, Junjiang\|Yang, Dongyang\|Ma, Dong
PMID:	29643917

1913.
Journal:	J Gastroenterol Hepatol. 2018 Oct;33(10):1737-1744.
Title:	Costs and outcomes of Lynch syndrome screening in the Australian colorectal cancer population.
Author:	Cenin, Dayna R\|Naber, Steffie K\|Lansdorp-Vogelaar, Iris\|Jenkins, Mark A\|Buchanan, Daniel D\|Preen, David B\|Ee, Hooi C\|O'Leary, Peter
PMID:	29645364

1914.
Journal:	Pathol Res Pract. 2018 May;214(5):720-726.
Title:	Phenotypic and genotypic differences in colorectal carcinoma among Caucasians, Asians, and Hispanics lack statistical significance.
Author:	Hoffman, Sara J\|Wu, Mark Li-Cheng
PMID:	29650442

1915.
Journal:	Clin Gastroenterol Hepatol. 2018 Apr 13. pii: S1542-3565(18)30371-9.
Title:	The Association Between Mutations in BRAF and Colorectal Cancer-Specific Survival Depends on Microsatellite Status and Tumor Stage.
Author:	Blaker, Hendrik\|Alwers, Elizabeth\|Arnold, Alexander\|Herpel, Esther\|Tagscherer, Katrin E\|Roth, Wilfried\|Jansen, Lina\|Walter, Viola\|Kloor, Matthias\|Chang-Claude, Jenny\|Brenner, Hermann\|Hoffmeister, Michael
PMID:	29660527

1916.
Journal:	Oncotarget. 2018 Mar 27;9(23):16477-16488.
Title:	Clinical outcomes of women with ovarian metastases of colorectal cancer treated with oophorectomy with respect to their somatic mutation profiles.
Author:	Mori, Yoshiko\|Nyuya, Akihiro\|Yasui, Kazuya\|Toshima, Toshiaki\|Kawai, Takashi\|Taniguchi, Fumitaka\|Kimura, Keisuke\|Inada, Ryo\|Nishizaki, Masahiko\|Haraga, Junko\|Nakamura, Keiichiro\|Umeda, Yuzo\|Kishimoto, Hiroyuki\|Fujiwara, Toshiyoshi\|Katata, Yosuke\|Yamaguchi,
PMID:	29662660

1917.
Journal:	Tumour Biol. 2018 Apr;40(4):1010428318770957.
Title:	Cyclin-dependent kinase 1 targeting improves sensitivity to radiation in BRAF V600E colorectal carcinoma cells.
Author:	Spagnoletti, Girolamo\|Li Bergolis, Valeria\|Piscazzi, Annamaria\|Giannelli, Francesca\|Condelli, Valentina\|Sisinni, Lorenza\|Bove, Giuseppe\|Storto, Giovanni\|Landriscina, Matteo
PMID:	29663854

1918.
Journal:	Gut. 2018 Apr 17. pii: gutjnl-2017-315920.
Title:	Genetic editing of colonic organoids provides a molecularly distinct and orthotopic preclinical model of serrated carcinogenesis.
Author:	Lannagan, Tamsin R M\|Lee, Young K\|Wang, Tongtong\|Roper, Jatin\|Bettington, Mark L\|Fennell, Lochlan\|Vrbanac, Laura\|Jonavicius, Lisa\|Somashekar, Roshini\|Gieniec, Krystyna\|Yang, Miao\|Ng, Jia Q\|Suzuki, Nobumi\|Ichinose, Mari\|Wright, Josephine A\|Kobayashi, Hirok
PMID:	29666172

1919.
Journal:	Sci Rep. 2018 Apr 17;8(1):6076.
Title:	Mutation status and prognostic values of KRAS, NRAS, BRAF and PIK3CA in 353 Chinese colorectal cancer patients.
Author:	Guo, Fang\|Gong, Hai\|Zhao, Huanhuan\|Chen, Jing\|Zhang, Yiming\|Zhang, Lihua\|Shi, Xin\|Zhang, Aifeng\|Jin, Hui\|Zhang, Jianqiong\|He, Youji
PMID:	29666387

1920.
Journal:	Virchows Arch. 2018 Aug;473(2):199-207.
Title:	The prognostic impact of CDX2 correlates with the underlying mismatch repair status and BRAF mutational status but not with distant metastasis in colorectal cancer.
Author:	Neumann, Jens\|Heinemann, Volker\|Engel, Jutta\|Kirchner, Thomas\|Stintzing, Sebastian
PMID:	29675807

1921.
Journal:	Middle East J Dig Dis. 2018 Jan;10(1):18-23.
Title:	Frequency of NRAS Gene Mutation in Wild Type KRAS and BRAF Colorectal Cancers; a Single Center Study.
Author:	Momenzadeh, Hooria\|Mirzai, Mitra\|Jowkar, Zahra\|Geramizadeh, Bita
PMID:	29682243

1922.
Journal:	PLoS One. 2018 Apr 25;13(4):e0196233.
Title:	One-carbon metabolism biomarkers and genetic variants in relation to colorectal cancer risk by KRAS and BRAF mutation status.
Author:	Myte, Robin\|Gylling, Bjorn\|Haggstrom, Jenny\|Schneede, Jorn\|Lofgren-Burstrom, Anna\|Huyghe, Jeroen R\|Hallmans, Goran\|Meyer, Klaus\|Johansson, Ingegerd\|Ueland, Per Magne\|Palmqvist, Richard\|Van Guelpen, Bethany
PMID:	29694444

1923.
Journal:	Virchows Arch. 2018 Jun;472(6):959-968.
Title:	Performance validation of an amplicon-based targeted next-generation sequencing assay and mutation profiling of 648 Chinese colorectal cancer patients.
Author:	Wang, Yajian\|Liu, Haijing\|Hou, Yingyong\|Zhou, Xiaoyan\|Liang, Li\|Zhang, Zhihong\|Shi, Huaiyin\|Xu, Sanpeng\|Hu, Peizhen\|Zheng, Zuyu\|Liu, Rui\|Tang, Tingdong\|Ye, Feng\|Liang, Zhiyong\|Bu, Hong
PMID:	29705968

1924.
Journal:	Can J Gastroenterol Hepatol. 2018 Mar 7;2018:4248971.
Title:	RAS/BRAF Circulating Tumor DNA Mutations as a Predictor of Response to First-Line Chemotherapy in Metastatic Colorectal Cancer Patients.
Author:	Yao, Jiannan\|Zang, Wanchun\|Ge, Yang\|Weygant, Nathaniel\|Yu, Pan\|Li, Lei\|Rao, Guanhua\|Jiang, Zhi\|Yan, Rui\|He, Linjia\|Yu, Yang\|Jin, Mulan\|Cheng, Gang\|An, Guangyu
PMID:	29707525

1925.
Journal:	Expert Rev Mol Diagn. 2018 Jun;18(6):499-512.
Title:	BRAF-mutant colorectal cancer, a different breed evolving.
Author:	Lai, Eleonora\|Pretta, Andrea\|Impera, Valentino\|Mariani, Stefano\|Giampieri, Riccardo\|Casula, Laura\|Pusceddu, Valeria\|Coni, Pierpaolo\|Fanni, Daniela\|Puzzoni, Marco\|Demurtas, Laura\|Ziranu, Pina\|Faa, Gavino\|Scartozzi, Mario
PMID:	29708446

1926.
Journal:	Anticancer Res. 2018 May;38(5):2891-2895.
Title:	Double KRAS and BRAF Mutations in Surgically Treated Colorectal Cancer Liver Metastases: An International, Multi-institutional Case Series.
Author:	Deshwar, Amar\|Margonis, Georgios Antonios\|Andreatos, Nikolaos\|Barbon, Carlotta\|Wang, Jaeyun\|Buettner, Stefan\|Wagner, Doris\|Sasaki, Kazunari\|Beer, Andrea\|Loes, Inger Marie\|Pikoulis, Emmanouil\|Damaskos, Christos\|Garmpis, Nikolaos\|Kamphues, Karsten\|He, Jin\|K
PMID:	29715113

1927.
Journal:	J Natl Cancer Inst. 2018 Apr 27. pii: 4989438.
Title:	Molecular Landscape of ERBB2/ERBB3 Mutated Colorectal Cancer.
Author:	Loree, Jonathan M\|Bailey, Ann M\|Johnson, Amber M\|Yu, Yao\|Wu, Wenhui\|Bristow, Christopher A\|Davis, Jennifer S\|Shaw, Kenna R\|Broaddus, Russell\|Banks, Kimberly C\|Lanman, Richard B\|Meric-Bernstam, Funda\|Overman, Michael J\|Kopetz, Scott\|Raghav, Kanwal
PMID:	29718453

1928.
Journal:	Clin Colon Rectal Surg. 2018 May;31(3):147-152.
Title:	Update on Sporadic Colorectal Cancer Genetics.
Author:	Hardiman, Karin M
PMID:	29720900

1929.
Journal:	Exp Ther Med. 2018 May;15(5):4229-4242.
Title:	Upregulation of c-mesenchymal epithelial transition expression and RAS mutations are associated with late lung metastasis and poor prognosis in colorectal carcinoma.
Author:	Liu, Jianhua\|Zeng, Weiqiang\|Huang, Chengzhi\|Wang, Junjiang\|Xu, Lishu\|Ma, Dong
PMID:	29725370

1930.
Journal:	Oncol Lett. 2018 May;15(5):7794-7798.
Title:	Downregulation of BRAF-activated non-protein coding RNA in patients with hepatitis B virus-associated hepatocellular carcinoma.
Author:	Zhao, Na-Na\|Wang, Cheng\|Lai, Cheng-Cai\|Cheng, Si-Jie\|Yan, Jin\|Hong, Zhi-Xian\|Yu, Lin-Xiang\|Zhu, Zhen-Yu\|Zhang, Pei-Rui\|Wang, Zhao-Hai\|Wang, Xi-Liang\|Zhang, Shao-Geng\|Yang, Peng-Hui
PMID:	29725471

1931.
Journal:	Histopathology. 2018 Sep;73(3):444-453.
Title:	Immunohistochemical and genetic characteristics of a colorectal mucin-rich variant of traditional serrated adenoma.
Author:	Hiromoto, Takafumi\|Murakami, Takashi\|Akazawa, Yoichi\|Sasahara, Noriko\|Saito, Tsuyoshi\|Sakamoto, Naoto\|Mitomi, Hiroyuki\|Nagahara, Akihito\|Yao, Takashi
PMID:	29729192

1932.
Journal:	Pathol Res Pract. 2018 Jun;214(6):826-834.
Title:	Comprehensive expression analysis of TNF-related apoptosis-inducing ligand and its receptors in colorectal cancer: Correlation with MAPK alterations and clinicopathological associations.
Author:	Tsikalakis, Spyridon\|Chatziandreou, Ilenia\|Michalopoulos, Nikolaos V\|Theodoropoulos, Georgios E\|Sakellariou, Stratigoula\|Korkolopoulou, Penelope\|Patsouris, Efstratios\|Saetta, Angelica A
PMID:	29731264

1933.
Journal:	Ann Diagn Pathol. 2018 Aug;35:48-52.
Title:	Serrated epithelial colorectal polyps (hyperplastic polyps, sessile serrated adenomas) with perineurial stroma: Clinicopathological and molecular analysis of a new series.
Author:	Erlenbach-Wunsch, Katharina\|Bihl, Michel\|Hartmann, Arndt\|Groisman, Gabriel M\|Vieth, Michael\|Agaimy, Abbas
PMID:	29747061

1934.
Journal:	Cancer. 2018 Aug 1;124(15):3145-3153.
Title:	Universal screening of both endometrial and colon cancers increases the detection of Lynch syndrome.
Author:	Adar, Tomer\|Rodgers, Linda H\|Shannon, Kristen M\|Yoshida, Makoto\|Ma, Tianle\|Mattia, Anthony\|Lauwers, Gregory Y\|Iafrate, Anthony J\|Hartford, Nicole M\|Oliva, Esther\|Chung, Daniel C
PMID:	29750335

1935.
Journal:	Curr Treat Options Oncol. 2018 May 11;19(6):29.
Title:	Promising New Agents for Colorectal Cancer.
Author:	Das, Satya\|Ciombor, Kristen K\|Haraldsdottir, Sigurdis\|Goldberg, Richard M
PMID:	29752549

1936.
Journal:	Br J Cancer. 2018 May 14. pii: 10.1038/s41416-018-0086-x.
Title:	AZ304, a novel dual BRAF inhibitor, exerts anti-tumour effects in colorectal cancer independently of BRAF genetic status.
Author:	Ma, Rui\|Xu, Ling\|Qu, Xiujuan\|Che, Xiaofang\|Zhang, Ye\|Fan, Yibo\|Li, Ce\|Guo, Tianshu\|Hou, Kezuo\|Hu, Xuejun\|Drew, Lisa\|Shen, Minhui\|Cheung, Tony\|Liu, Yunpeng
PMID:	29755114

1937.
Journal:	Oncotarget. 2018 Apr 17;9(29):20761-20768.
Title:	Clinical application of targeted next-generation sequencing for colorectal cancer patients: a multicentric Belgian experience.
Author:	D'Haene, Nicky\|Fontanges, Quitterie\|De Neve, Nancy\|Blanchard, Oriane\|Melendez, Barbara\|Delos, Monique\|Dehou, Marie-Francoise\|Maris, Calliope\|Nagy, Nathalie\|Rousseau, Emmanuel\|Vandenhove, Josse\|Gilles, Andre\|De Prez, Carine\|Verset, Laurine\|Van Craynest, Ma
PMID:	29755687

1938.
Journal:	Jpn J Clin Oncol. 2018 Jul 1;48(7):609-618.
Title:	Clinicopathological and molecular differences between right-sided and left-sided colorectal cancer in Japanese patients.
Author:	Natsume, Soichiro\|Yamaguchi, Tatsuro\|Takao, Misato\|Iijima, Takeru\|Wakaume, Rika\|Takahashi, Keiichi\|Matsumoto, Hiroshi\|Nakano, Daisuke\|Horiguchi, Shin-Ichiro\|Koizumi, Koichi\|Miyaki, Michiko
PMID:	29767751

1939.
Journal:	Cancer Med. 2018 May 17.
Title:	Primary tumor sidedness is an independent prognostic marker for survival in metastatic colorectal cancer: Results from a large retrospective cohort with mutational analysis.
Author:	Kamran, Sophia C\|Clark, Jeffrey W\|Zheng, Hui\|Borger, Darrell R\|Blaszkowsky, Lawrence S\|Allen, Jill N\|Kwak, Eunice L\|Wo, Jennifer Y\|Parikh, Aparna R\|Nipp, Ryan D\|Murphy, Janet E\|Goyal, Lipika\|Zhu, Andrew X\|Iafrate, A John\|Corcoran, Ryan B\|Ryan, David P\|Hon
PMID:	29771009

1940.
Journal:	Clin Lab Med. 2018 Jun;38(2):311-342.
Title:	Molecular Diagnostics in Colorectal Carcinoma: Advances and Applications for 2018.
Author:	Bhalla, Amarpreet\|Zulfiqar, Muhammad\|Bluth, Martin H
PMID:	29776633

1941.
Journal:	Mol Cancer Res. 2018 Sep;16(9):1385-1395.
Title:	Centrosome Linker-induced Tetraploid Segregation Errors Link Rhabdoid Phenotypes and Lethal Colorectal Cancers.
Author:	Remo, Andrea\|Manfrin, Erminia\|Parcesepe, Pietro\|Ferrarini, Alberto\|Han, Hye Seung\|Mickys, Ugnius\|Laudanna, Carmelo\|Simbolo, Michele\|Malanga, Donatella\|Oliveira, Duarte Mendes\|Baritono, Elisabetta\|Colangelo, Tommaso\|Sabatino, Lina\|Giuliani, Jacopo\|Molinari
PMID:	29784668

1942.
Journal:	J Natl Compr Canc Netw. 2018 May;16(5S):611-615.
Title:	Optimizing Adjuvant Therapy for Localized Colon Cancer and Treatment Selection in Advanced Colorectal Cancer.
Author:	Grothey, Axel\|Venook, Alan P
PMID:	29784738

1943.
Journal:	Neoplasma. 2018 Mar 14;65(3):415-424.
Title:	Novel insights into transcriptional dysregulation in colorectal cancer.
Author:	Feodorova, Y\|Tashkova, D\|Koev, I\|Todorov, A\|Kostov, G\|Simitchiev, K\|Belovejdov, V\|Dimov, R\|Sarafian, V
PMID:	29788743

1944.
Journal:	Drugs. 2018 Jun;78(8):789-798.
Title:	Colorectal Cancer: Why Does Side Matter?
Author:	Gallois, Claire\|Pernot, Simon\|Zaanan, Aziz\|Taieb, Julien
PMID:	29790124

1945.
Journal:	Arch Pathol Lab Med. 2018 May 23.
Title:	Colorectal Liver Metastases: A Pathologist's Guide to Creating an Informative Report and Improving Patient Care.
Author:	Moreno Prats, Mariana\|Sasatomi, Eizaburo\|Stevenson, Heather L
PMID:	29790787

1946.
Journal:	Oncotarget. 2018 May 1;9(33):22895-22906.
Title:	Comprehensive molecular analysis based on somatic copy number alterations in intramucosal colorectal neoplasias and early invasive colorectal cancers.
Author:	Sugai, Tamotsu\|Eizuka, Makoto\|Habano, Wataru\|Fujita, Yasuko\|Sato, Ayaka\|Sugimoto, Ryo\|Otsuka, Kouki\|Yamamoto, Eiichiro\|Matsumoto, Takayuki\|Suzuki, Hiromu
PMID:	29796160

1947.
Journal:	Curr Treat Options Oncol. 2018 May 23;19(6):31.
Title:	Right Versus Left Colon Cancer: Resectable and Metastatic Disease.
Author:	Ghidini, Michele\|Petrelli, Fausto\|Tomasello, Gianluca
PMID:	29796712

1948.
Journal:	JAMA Surg. 2018 Jul 18;153(7):e180996.
Title:	Association of BRAF Mutations With Survival and Recurrence in Surgically Treated Patients With Metastatic Colorectal Liver Cancer.
Author:	Margonis, Georgios Antonios\|Buettner, Stefan\|Andreatos, Nikolaos\|Kim, Yuhree\|Wagner, Doris\|Sasaki, Kazunari\|Beer, Andrea\|Schwarz, Christoph\|Loes, Inger Marie\|Smolle, Maria\|Kamphues, Carsten\|He, Jin\|Pawlik, Timothy M\|Kaczirek, Klaus\|Poultsides, George\|Lonn
PMID:	29799910

1949.
Journal:	Mutagenesis. 2018 Sep 17;33(3):225-230.
Title:	Prevalence and prognostic relevance of BrafV600E mutation in colorectal carcinomas from Kashmir (North India) valley.
Author:	Eachkoti, Rafiqa\|Farooq, Sanah\|Syeed, Sheikh Imran\|Wani, Hilal Ahmed\|Majid, Sabhiya\|Pampori, Mohd Rafiq
PMID:	29800258

1950.
Journal:	Clin Transl Oncol. 2018 May 25. pii: 10.1007/s12094-018-1874-8.
Title:	Molecular subtypes in early colorectal cancer associated with clinical features and patient prognosis.
Author:	Gil-Raga, M\|Jantus-Lewintre, E\|Gallach, S\|Giner-Bosch, V\|Frangi-Caregnato, A\|Safont-Aguilera, M J\|Garde-Noguera, J\|Zorraquino-Pina, E\|Garcia-Martinez, M\|Camps-Herrero, C
PMID:	29802524

1951.
Journal:	J Cancer. 2018 Apr 19;9(10):1791-1796.
Title:	The impact of microsatellite instability status and sidedness of the primary tumor on the effect of bevacizumab-containing chemotherapy in patients with metastatic colorectal cancer.
Author:	Kim, Seung Tae\|Kim, Hee Kyung\|Lee, Jeeyun\|Park, Se Hoon\|Lim, Ho Yeong\|Park, Young Suk\|Kang, Won Ki\|Park, Joon Oh
PMID:	29805705

1952.
Journal:	Nat Med. 2018 Jul;24(7):961-967.
Title:	SHP2 is required for growth of KRAS-mutant non-small-cell lung cancer in vivo.
Author:	Mainardi, Sara\|Mulero-Sanchez, Antonio\|Prahallad, Anirudh\|Germano, Giovanni\|Bosma, Astrid\|Krimpenfort, Paul\|Lieftink, Cor\|Steinberg, Jeffrey D\|de Wit, Niels\|Goncalves-Ribeiro, Samuel\|Nadal, Ernest\|Bardelli, Alberto\|Villanueva, Alberto\|Bernards, Rene
PMID:	29808006

1953.
Journal:	Br J Cancer. 2018 Jul;119(2):213-219.
Title:	High-serum MMP-8 levels are associated with decreased survival and systemic inflammation in colorectal cancer.
Author:	Sirnio, Paivi\|Tuomisto, Anne\|Tervahartiala, Taina\|Sorsa, Timo\|Klintrup, Kai\|Karhu, Toni\|Herzig, Karl-Heinz\|Makela, Jyrki\|Karttunen, Tuomo J\|Salo, Tuula\|Makinen, Markus J\|Vayrynen, Juha P
PMID:	29808017

1954.
Journal:	Cell Death Dis. 2018 May 29;9(6):640.
Title:	miR-550a-3-5p acts as a tumor suppressor and reverses BRAF inhibitor resistance through the direct targeting of YAP.
Author:	Choe, Min Ho\|Yoon, Yina\|Kim, Joon\|Hwang, Sang-Gu\|Han, Young-Hoon\|Kim, Jae-Sung
PMID:	29844307

1955.
Journal:	Oncotarget. 2018 May 8;9(35):24081-24096.
Title:	Combined assessment of the TNM stage and BRAF mutational status at diagnosis in sporadic colorectal cancer patients.
Author:	Sayagues, Jose Maria\|Del Carmen, Sofia\|Del Mar Abad, Maria\|Corchete, Luis Antonio\|Bengoechea, Oscar\|Anduaga, Maria Fernanda\|Baldeon, Maria Jesus\|Cruz, Juan Jesus\|Alcazar, Jose Antonio\|Angoso, Maria\|Gonzalez, Marcos\|Garcia, Jacinto\|Munoz-Bellvis, Luis\|Orfa
PMID:	29844874

1956.
Journal:	Future Oncol. 2018 Jun;14(14):1339-1346.
Title:	Phase III study with FOLFIRI + cetuximab versus FOLFIRI + cetuximab followed by cetuximab alone in RAS and BRAF WT mCRC.
Author:	Pinto, Carmine\|Normanno, Nicola\|Orlandi, Armando\|Fenizia, Francesca\|Damato, Angela\|Maiello, Evaristo\|Tamburini, Emiliano\|Di Costanzo, Francesco\|Tonini, Giuseppe\|Bilancia, Domenico\|Corsi, Domenico\|Pisconti, Salvatore\|Ferrau, Francesco\|Gori, Stefania\|Daniel
PMID:	29846100

1957.
Journal:	Case Rep Surg. 2018 Apr 15;2018:8782328.
Title:	BRAF Inhibitors for BRAF V600E Mutant Colorectal Cancers: Literature Survey and Case Report.
Author:	Peker, Yasar Subutay\|Can, Mehmet Fatih\|Ozerhan, Ismail Hakki\|Yagci, Gokhan\|Zeybek, Nazif\|Kavakli, Kutan\|Gurkok, Sedat\|Gozubuyuk, Alper\|Genc, Onur\|Erdem, Gokhan\|Ozet, Ahmet\|Gerek, Mustafa\|Peker, Yusuf
PMID:	29850361

1958.
Journal:	Clin Adv Hematol Oncol. 2018 May;16(5):333-335.
Title:	How should BRAF V600E-mutated colorectal cancer be treated?
Author:	Kopetz, Scott
PMID:	29851929

1959.
Journal:	Oncotarget. 2018 Apr 27;9(32):22749-22768.
Title:	Simultaneous identification of clinically relevant single nucleotide variants, copy number alterations and gene fusions in solid tumors by targeted next-generation sequencing.
Author:	Oliveira, Duarte Mendes\|Mirante, Teresa\|Mignogna, Chiara\|Scrima, Marianna\|Migliozzi, Simona\|Rocco, Gaetano\|Franco, Renato\|Corcione, Francesco\|Viglietto, Giuseppe\|Malanga, Donatella\|Rizzuto, Antonia
PMID:	29854313

1960.
Journal:	Oncoscience. 2018 Apr 29;5(3-4):51-53.
Title:	Combination drug development in BRAF mutant colorectal cancer.
Author:	Lam, Michael\|Pant, Shubham\|Yap, Timothy A
PMID:	29854866

1961.
Journal:	Oncoscience. 2018 Apr 29;5(3-4):57-58.
Title:	Targeting parallel bypass signaling to combat adaptive resistance to BRAF inhibition in colorectal cancer.
Author:	Gao, Chenxi\|Hu, Jing
PMID:	29854868

1962.
Journal:	Med Oncol. 2018 May 31;35(7):101.
Title:	Phase II study of panitumumab combined with capecitabine and oxaliplatin as first-line treatment in metastatic colorectal cancer patients: clinical results including extended tumor genotyping.
Author:	Papaxoinis, George\|Kotoula, Vassiliki\|Giannoulatou, Eleni\|Koliou, Georgia-Angeliki\|Karavasilis, Vasilios\|Lakis, Sotirios\|Koureas, Andreas\|Bobos, Mattheos\|Chalaralambous, Elpida\|Daskalaki, Emily\|Chatzopoulos, Kyriakos\|Tsironis, George\|Pazarli, Elisavet\|Chr
PMID:	29855806

1963.
Journal:	PLoS One. 2018 Jun 7;13(6):e0198795.
Title:	Development of ultra-short PCR assay to reveal BRAF V600 mutation status in Thai colorectal cancer tissues.
Author:	Chat-Uthai, Nunthawut\|Vejvisithsakul, Pichpisith\|Udommethaporn, Sutthirat\|Meesiri, Puttarakun\|Danthanawanit, Chetiya\|Wongchai, Yannawan\|Teerapakpinyo, Chinachote\|Shuangshoti, Shanop\|Poungvarin, Naravat
PMID:	29879227

1964.
Journal:	Biol Chem. 2018 Jun 27;399(7):649-659.
Title:	Oncogenic BRAFV600E drives expression of MGL ligands in the colorectal cancer cell line HT29 through N-acetylgalactosamine-transferase 3.
Author:	Sahasrabudhe, Neha M\|Lenos, Kristiaan\|van der Horst, Joost C\|Rodriguez, Ernesto\|van Vliet, Sandra J
PMID:	29894293

1965.
Journal:	Oncoimmunology. 2018 Mar 19;7(7):e1442999.
Title:	TIME (Tumor Immunity in the MicroEnvironment) classification based on tumor CD274 (PD-L1) expression status and tumor-infiltrating lymphocytes in colorectal carcinomas.
Author:	Hamada, Tsuyoshi\|Soong, Thing Rinda\|Masugi, Yohei\|Kosumi, Keisuke\|Nowak, Jonathan A\|da Silva, Annacarolina\|Mu, Xinmeng Jasmine\|Twombly, Tyler S\|Koh, Hideo\|Yang, Juhong\|Song, Mingyang\|Liu, Li\|Gu, Mancang\|Shi, Yan\|Nosho, Katsuhiko\|Morikawa, Teppei\|Inamura,
PMID:	29900052

1966.
Journal:	Oncoimmunology. 2018 Mar 26;7(7):e1445949.
Title:	Deficiency of host CD96 and PD-1 or TIGIT enhances tumor immunity without significantly compromising immune homeostasis.
Author:	Harjunpaa, Heidi\|Blake, Stephen J\|Ahern, Elizabeth\|Allen, Stacey\|Liu, Jing\|Yan, Juming\|Lutzky, Viviana\|Takeda, Kazuyoshi\|Aguilera, Amy Roman\|Guillerey, Camille\|Mittal, Deepak\|Li, Xian Yang\|Dougall, William C\|Smyth, Mark J\|Teng, Michele W L
PMID:	29900061

1967.
Journal:	Mol Oncol. 2018 Sep;12(9):1639-1655.
Title:	Prognostic, predictive, and pharmacogenomic assessments of CDX2 refine stratification of colorectal cancer.
Author:	Bruun, Jarle\|Sveen, Anita\|Barros, Rita\|Eide, Peter W\|Eilertsen, Ina\|Kolberg, Matthias\|Pellinen, Teijo\|David, Leonor\|Svindland, Aud\|Kallioniemi, Olli\|Guren, Marianne G\|Nesbakken, Arild\|Almeida, Raquel\|Lothe, Ragnhild A
PMID:	29900672

1968.
Journal:	Sci Rep. 2018 Jun 15;8(1):9204.
Title:	Alterations of mTOR signaling impact metabolic stress resistance in colorectal carcinomas with BRAF and KRAS mutations.
Author:	Fritsche-Guenther, Raphaela\|Zasada, Christin\|Mastrobuoni, Guido\|Royla, Nadine\|Rainer, Roman\|Rossner, Florian\|Pietzke, Matthias\|Klipp, Edda\|Sers, Christine\|Kempa, Stefan
PMID:	29907857

1969.
Journal:	Cancer Sci. 2018 Aug;109(8):2567-2575.
Title:	Phase II trial of biweekly cetuximab and irinotecan as third-line therapy for pretreated KRAS exon 2 wild-type colorectal cancer.
Author:	Osumi, Hiroki\|Shinozaki, Eiji\|Mashima, Tetsuo\|Wakatsuki, Takeru\|Suenaga, Mitsukuni\|Ichimura, Takashi\|Ogura, Mariko\|Ota, Yumiko\|Nakayama, Izuma\|Takahari, Daisuke\|Chin, Keisho\|Miki, Yoshio\|Yamaguchi, Kensei
PMID:	29908105

1970.
Journal:	Ann Transl Med. 2018 May;6(9):159.
Title:	Colorectal cancer genomics and designing rational trials.
Author:	Mondaca, Sebastian\|Yaeger, Rona
PMID:	29911107

1971.
Journal:	Cancer Res. 2018 Aug 15;78(16):4533-4548.
Title:	The Endosomal Protein CEMIP Links WNT Signaling to MEK1-ERK1/2 Activation in Selumetinib-Resistant Intestinal Organoids.
Author:	Duong, Hong Quan\|Nemazanyy, Ivan\|Rambow, Florian\|Tang, Seng Chuan\|Delaunay, Sylvain\|Tharun, Lars\|Florin, Alexandra\|Buttner, Reinhard\|Vandaele, Daniel\|Close, Pierre\|Marine, Jean-Christophe\|Shostak, Kateryna\|Chariot, Alain
PMID:	29915160

1972.
Journal:	Sci Rep. 2018 Jun 18;8(1):9296.
Title:	PTPRS Regulates Colorectal Cancer RAS Pathway Activity by Inactivating Erk and Preventing Its Nuclear Translocation.
Author:	Davis, Thomas B\|Yang, Mingli\|Schell, Michael J\|Wang, Heiman\|Ma, Le\|Pledger, W Jack\|Yeatman, Timothy J
PMID:	29915291

1973.
Journal:	Clin Cancer Res. 2018 Oct 1;24(19):4745-4753.
Title:	Prognostic Value of Methylator Phenotype in Stage III Colon Cancer Treated with Oxaliplatin-based Adjuvant Chemotherapy.
Author:	Gallois, Claire\|Taieb, Julien\|Le Corre, Delphine\|Le Malicot, Karine\|Tabernero, Josep\|Mulot, Claire\|Seitz, Jean-Francois\|Aparicio, Thomas\|Folprecht, Gunnar\|Lepage, Come\|Mini, Enrico\|Van Laethem, Jean-Luc\|Emile, Jean-Francois\|Laurent-Puig, Pierre
PMID:	29921730

1974.
Journal:	Surg Oncol. 2018 Jun;27(2):280-288.
Title:	Clinical significance and prognostic relevance of KRAS, BRAF, PI3K and TP53 genetic mutation analysis for resectable and unresectable colorectal liver metastases: A systematic review of the current evidence.
Author:	Tsilimigras, Diamantis I\|Ntanasis-Stathopoulos, Ioannis\|Bagante, Fabio\|Moris, Demetrios\|Cloyd, Jordan\|Spartalis, Eleftherios\|Pawlik, Timothy M
PMID:	29937183

1975.
Journal:	Int J Colorectal Dis. 2018 Jun 25. pii: 10.1007/s00384-018-3107-6.
Title:	Brain metastases in colorectal cancer: prognostic factors and survival analysis.
Author:	Del Carpio Huerta, Luis\|Virgili Manrique, Anna Cristina\|Szafranska, Justyna\|Martin-Richard, Marta\|Paez Lopez-Bravo, David\|Sebio Garcia, Ana\|Espinosa Mariscal, Inigo\|Gomila Pons, Paula\|Andres Granyo, Marta\|Barba Joaquin, Andres\|Barnadas Molins, Agusti\|Tobe
PMID:	29943356

1976.
Journal:	Am Soc Clin Oncol Educ Book. 2018 May 23;(38):978-997.
Title:	Liquid Biopsy to Identify Actionable Genomic Alterations.
Author:	Ou, Sai-Hong Ignatius\|Nagasaka, Misako\|Zhu, Viola W
PMID:	30231331

1977.
Journal:	Cancer Manag Res. 2018 Sep 26;10:3911-3929.
Title:	Prognostic value of the combination of microsatellite instability and BRAF mutation in colorectal cancer.
Author:	Yang, Yingchi\|Wang, Dong\|Jin, Lan\|Wu, Guocong\|Bai, Zhigang\|Wang, Jin\|Yao, Hongwei\|Zhang, Zhongtao
PMID:	30310312

1978.
Journal:	Br J Cancer. 2018 Oct;119(7):908.
Title:	Comment on "ERK and p38MAPK combine to improve survival in patients with BRAF mutant colorectal cancer".
Author:	Uzunparmak, Burak\|Sahin, Ibrahim H
PMID:	30297772

1979.
Journal:	Br J Cancer. 2018 Oct;119(7):909.
Title:	Reply to comment of "ERK and p38MAPK combine to improve survival in patients with BRAF mutant colorectal cancer".
Author:	Roseweir, Antonia K\|McMillan, Donald C\|Edwards, Joanne
PMID:	30297771

1980.
Journal:	Asia Pac J Clin Oncol. 2018 Oct 7.
Title:	Current mismatch repair deficiency tumor testing practices and capabilities: A survey of Australian pathology providers.
Author:	Mascarenhas, Lyon\|Shanley, Susan\|Mitchell, Gillian\|Spurdle, Amanda B\|Macrae, Finlay\|Pachter, Nicholas\|Buchanan, Daniel D\|Ward, Robyn L\|Fox, Stephen\|Duxbury, Elaine\|Driessen, Rebecca\|Boussioutas, Alex
PMID:	30294856

1981.
Journal:	Mol Cancer Res. 2018 Oct 1. pii: 1541-7786.MCR-17-0554.
Title:	Efficacy of a Covalent ERK1/2 Inhibitor, CC-90003, in KRAS Mutant Cancer Models Reveals Novel Mechanisms of Response and Resistance.
Author:	Aronchik, Ida\|Dai, Yumin\|Labenski, Matt\|Barnes, Carmen\|Jones, Terri\|QIao, Lixin\|Beebe, Lisa\|Malek, Mehnaz\|Elis, Winfried\|Shi, Tao\|Mavrommatis, Konstantinos\|Bray, Gordon L\|Filvaroff, Ellen H
PMID:	30275173

1982.
Journal:	Genes Chromosomes Cancer. 2018 Sep 28.
Title:	Small RNA sequencing of sessile serrated polyps identifies microRNA profile associated with colon cancer.
Author:	Kanth, Priyanka\|Hazel, Mark W\|Boucher, Kenneth M\|Yang, Zhihong\|Wang, Li\|Bronner, Mary P\|Boylan, Katherine\|Burt, Randall W\|Westover, Michelle\|Neklason, Deborah W\|Delker, Don A
PMID:	30265426

1983.
Journal:	Clin Epigenetics. 2018 Sep 26;10(1):120.
Title:	CDX2 in colorectal cancer is an independent prognostic factor and regulated by promoter methylation and histone deacetylation in tumors of the serrated pathway.
Author:	Graule, Janina\|Uth, Kristin\|Fischer, Elia\|Centeno, Irene\|Galvan, Jose A\|Eichmann, Micha\|Rau, Tilman T\|Langer, Rupert\|Dawson, Heather\|Nitsche, Ulrich\|Traeger, Peter\|Berger, Martin D\|Schnuriger, Beat\|Hadrich, Marion\|Studer, Peter\|Inderbitzin, Daniel\|Lugli,
PMID:	30257705

1984.
Journal:	Am J Pathol. 2018 Sep 19. pii: S0002-9440(18)30364-X.
Title:	The Amount of Bifidobacterium Genus in Colorectal Carcinoma Tissue in Relation to Tumor Characteristics and Clinical Outcome.
Author:	Kosumi, Keisuke\|Hamada, Tsuyoshi\|Koh, Hideo\|Borowsky, Jennifer\|Bullman, Susan\|Twombly, Tyler S\|Nevo, Daniel\|Masugi, Yohei\|Liu, Li\|da Silva, Annacarolina\|Chen, Yang\|Du, Chunxia\|Gu, Mancang\|Li, Chenxi\|Li, Wanwan\|Liu, Hongli\|Shi, Yan\|Mima, Kosuke\|Song, Mingy
PMID:	30243655

1985.
Journal:	Rev Gastroenterol Mex. 2018 Sep 17. pii: S0375-0906(18)30160-5.
Title:	Diagnosis and clinical behavior in patients with Lynch-like syndrome.
Author:	Adan-Merino, L\|Aldeguer-Martinez, M\|Alonso-Gamarra, E\|Valentin-Gomez, F\|Zaera-De la Fuente, C\|Martin-Chavarri, S
PMID:	30237080

1986.
Journal:	Am Soc Clin Oncol Educ Book. 2018 May 23;(38):231-238.
Title:	Molecular Subtypes and the Evolution of Treatment Decisions in Metastatic Colorectal Cancer.
Author:	Dienstmann, Rodrigo\|Salazar, Ramon\|Tabernero, Josep
PMID:	30231342

1987.
Journal:	J Natl Cancer Inst. 2018 Oct 11. pii: 5127125.
Title:	Smoking and Risk of Colorectal Cancer Sub-Classified by Tumor-Infiltrating T Cells.
Author:	Hamada, Tsuyoshi\|Nowak, Jonathan A\|Masugi, Yohei\|Drew, David A\|Song, Mingyang\|Cao, Yin\|Kosumi, Keisuke\|Mima, Kosuke\|Twombly, Tyler S\|Liu, Li\|Shi, Yan\|da Silva, Annacarolina\|Gu, Mancang\|Li, Wanwan\|Nosho, Katsuhiko\|Keum, NaNa\|Giannakis, Marios\|Meyerhardt, J
PMID:	30312431

1988.
Journal:	Cancer Immunol Res. 2018 Sep 18. pii: 2326-6066.CIR-18-0174.
Title:	Fusobacterium nucleatum in Colorectal Cancer Relates to Immune Response Differentially by Tumor Microsatellite Instability Status.
Author:	Hamada, Tsuyoshi\|Zhang, Xuehong\|Mima, Kosuke\|Bullman, Susan\|Sukawa, Yasutaka\|Nowak, Jonathan A\|Kosumi, Keisuke\|Masugi, Yohei\|Twombly, Tyler S\|Cao, Yin\|Song, Mingyang\|Liu, Li\|da Silva, Annacarolina\|Shi, Yan\|Gu, Mancang\|Li, Wanwan\|Koh, Hideo\|Nosho, Katsuhik
PMID:	30228205

1989.
Journal:	Eur J Cancer. 2018 Sep 12;103:98-107.
Title:	Vitamin D status after colorectal cancer diagnosis and patient survival according to immune response to tumour.
Author:	Hamada, Tsuyoshi\|Liu, Li\|Nowak, Jonathan A\|Mima, Kosuke\|Cao, Yin\|Ng, Kimmie\|Twombly, Tyler S\|Song, Mingyang\|Jung, Seungyoun\|Dou, Ruoxu\|Masugi, Yohei\|Kosumi, Keisuke\|Shi, Yan\|da Silva, Annacarolina\|Gu, Mancang\|Li, Wanwan\|Keum, NaNa\|Wu, Kana\|Nosho, Katsuhik
PMID:	30219720

1990.
Journal:	Eur Biophys J. 2018 Sep 14. pii: 10.1007/s00249-018-1334-y.
Title:	Electrostatic mechanism of V600E mutation-induced B-Raf constitutive activation in colorectal cancer: molecular implications for the selectivity difference between type-I and type-II inhibitors.
Author:	Liu, Tie\|Wang, Zhaoshun\|Guo, Peng\|Ding, Na
PMID:	30218115

1991.
Journal:	Int J Mol Sci. 2018 Sep 13;19(9). pii: ijms19092752.
Title:	Ascorbic Acid in Colon Cancer: From the Basic to the Clinical Applications.
Author:	El Halabi, Ibrahim\|Bejjany, Rachelle\|Nasr, Rihab\|Mukherji, Deborah\|Temraz, Sally\|Nassar, Farah J\|El Darsa, Haidar\|Shamseddine, Ali
PMID:	30217071

1992.
Journal:	Clin Colorectal Cancer. 2018 Jul 17. pii: S1533-0028(18)30133-6.
Title:	Prognostic Implications of Mucinous Differentiation in Metastatic Colorectal Carcinoma Can Be Explained by Distinct Molecular and Clinicopathologic Characteristics.
Author:	Khan, Maliha\|Loree, Jonathan M\|Advani, Shailesh M\|Ning, Jing\|Li, Wen\|Pereira, Allan A L\|Lam, Michael\|Raghav, Kanwal\|Morris, Van K\|Broaddus, Russell\|Maru, Dipen\|Overman, Michael J\|Kopetz, Scott
PMID:	30205948

1993.
Journal:	Cancer Cell Int. 2018 Sep 6;18:131.
Title:	Assessment of intratumor immune-microenvironment in colorectal cancers with extranodal extension of nodal metastases.
Author:	Fassan, Matteo\|Vianello, Luca\|Sacchi, Diana\|Fanelli, Giuseppe N\|Munari, Giada\|Scarpa, Marco\|Cappellesso, Rocco\|Loupakis, Fotios\|Lanza, Cristiano\|Salmaso, Roberta\|Mescoli, Claudia\|Valeri, Nicola\|Agostini, Marco\|D'Angelo, Edoardo\|Lonardi, Sara\|Pucciarelli,
PMID:	30202242

1994.
Journal:	Surgery. 2018 Sep 6. pii: S0039-6060(18)30483-5.
Title:	The location of the primary colon cancer has no impact on outcomes in patients undergoing cytoreductive surgery for peritoneal metastasis.
Author:	Peron, Julien\|Mercier, Frederic\|Tuech, Jean-Jacques\|Younan, Rami\|Sideris, Lucas\|Gelli, Maximiliano\|Dumont, Frederic\|Le Roy, Bertrand\|Sgarbura, Olivia\|Lo Dico, Rea\|Bibeau, Frederic\|Glehen, Olivier\|Passot, Guillaume
PMID:	30197280

1995.
Journal:	Int J Cancer. 2018 Sep 8.
Title:	PDEdelta inhibition impedes the proliferation and survival of human colorectal cancer cell lines harboring oncogenic KRas.
Author:	Klein, Christian H\|Truxius, Dina C\|Vogel, Holger A\|Harizanova, Jana\|Murarka, Sandip\|Martin-Gago, Pablo\|Bastiaens, Philippe I H
PMID:	30194764

1996.
Journal:	Oncogenesis. 2018 Sep 7;7(9):67.
Title:	MEK inhibitors induce apoptosis via FoxO3a-dependent PUMA induction in colorectal cancer cells.
Author:	Lin, Lin\|Ding, Dapeng\|Jiang, Yanmei\|Li, Yan\|Li, Shijun
PMID:	30190455

1997.
Journal:	Oncotarget. 2018 Sep 28;9(76):34279-34288.
Title:	Spatio-temporal tumor heterogeneity in metastatic CRC tumors: a mutational-based approach.
Author:	Del Carmen, Sofia\|Sayagues, Jose Maria\|Bengoechea, Oscar\|Anduaga, Maria Fernanda\|Alcazar, Jose Antonio\|Gervas, Ruth\|Garcia, Jacinto\|Orfao, Alberto\|Bellvis, Luis Munoz\|Sarasquete, Maria Eugenia\|Del Mar Abad, Maria
PMID:	30344942

1998.
Journal:	J Natl Cancer Inst. 2018 Nov 2. pii: 5156228.
Title:	Association of Aspirin and Nonsteroidal Anti-Inflammatory Drugs With Colorectal Cancer Risk by Molecular Subtypes.
Author:	Amitay, Efrat L\|Carr, Prudence R\|Jansen, Lina\|Walter, Viola\|Roth, Wilfried\|Herpel, Esther\|Kloor, Matthias\|Blaker, Hendrik\|Chang-Claude, Jenny\|Brenner, Hermann\|Hoffmeister, Michael
PMID:	30388256

1999.
Journal:	Br J Cancer. 2018 Nov 2. pii: 10.1038/s41416-018-0230-7.
Title:	Tumour budding is associated with the mesenchymal colon cancer subtype and RAS/RAF mutations: a study of 1320 colorectal cancers with Consensus Molecular Subgroup (CMS) data.
Author:	Trinh, Anne\|Ladrach, Claudia\|Dawson, Heather E\|Ten Hoorn, Sanne\|Kuppen, Peter J K\|Reimers, Marlies S\|Koopman, Miriam\|Punt, Cornelis J A\|Lugli, Alessandro\|Vermeulen, Louis\|Zlobec, Inti
PMID:	30385823

2000.
Journal:	J Cell Physiol. 2018 Oct 28.
Title:	Intratumoral infiltrating lymphocytes correlate with improved survival in colorectal cancer patients: Independent of oncogenetic features.
Author:	Nazemalhosseini-Mojarad, Ehsan\|Mohammadpour, Somayeh\|Torshizi Esafahani, Amir\|Gharib, Ehsan\|Larki, Pegah\|Moradi, Afshin\|Amin Porhoseingholi, Mohammad\|Asadzade Aghdaei, Hamid\|Kuppen, Peter J K\|Zali, Mohammad Reza
PMID:	30370522

2001.
Journal:	J Clin Pathol. 2018 Oct 25. pii: jclinpath-2018-205483.
Title:	Positive association of PIK3CA mutation with KRAS mutation but not BRAF mutation in colorectal cancer suggests co-selection is gene specific but not pathway specific.
Author:	Susanti, Susanti\|Fadhil, Wakkas\|Murtaza, Shamayal\|Hassall, James C\|Ebili, Henry O\|Oniscu, Anca\|Ilyas, Mohammad
PMID:	30361395

2002.
Journal:	Cancers (Basel). 2018 Oct 22;10(10). pii: cancers10100393.
Title:	Prognostic Values of EPDR1 Hypermethylation and Its Inhibitory Function on Tumor Invasion in Colorectal Cancer.
Author:	Chu, Chun-Ho\|Chang, Shih-Ching\|Wang, Hsiu-Hua\|Yang, Shung-Haur\|Lai, Kuo-Chu\|Lee, Te-Chang
PMID:	30360391

2003.
Journal:	Adv Sci (Weinh). 2018 Jul 30;5(10):1800614.
Title:	Simple and Low-Cost Sampling of Cell-Free Nucleic Acids from Blood Plasma for Rapid and Sensitive Detection of Circulating Tumor DNA.
Author:	Jin, Choong Eun\|Koo, Bonhan\|Lee, Tae Yoon\|Han, Kyudong\|Lim, Seok Byung\|Park, In Ja\|Shin, Yong
PMID:	30356899

2004.
Journal:	Oncogene. 2018 Oct 23. pii: 10.1038/s41388-018-0554-z.
Title:	Suppression of interferon gene expression overcomes resistance to MEK inhibition in KRAS-mutant colorectal cancer.
Author:	Wagner, Steve\|Vlachogiannis, Georgios\|De Haven Brandon, Alexis\|Valenti, Melanie\|Box, Gary\|Jenkins, Liam\|Mancusi, Caterina\|Self, Annette\|Manodoro, Floriana\|Assiotis, Ioannis\|Robinson, Penny\|Chauhan, Ritika\|Rust, Alistair G\|Matthews, Nik\|Eason, Kate\|Khan, K
PMID:	30353166

2005.
Journal:	Dis Colon Rectum. 2018 Oct 19.
Title:	Aspects of the Natural History of Sessile Serrated Adenomas/Polyps: Risk Indicators for Carcinogenesis in the Colorectal Mucosa?
Author:	Neary, Peter M\|Schwartzburg, David M\|Bora Cengiz, Turgot\|Kalady, Matthew F\|Church, James M
PMID:	30346367

2006.
Journal:	F1000Res. 2018 Sep 24;7.
Title:	Recent advances in understanding colorectal cancer.
Author:	Stintzing, Sebastian
PMID:	30345013

2007.
Journal:	PLoS One. 2018 Sep 6;13(9):e0203051.
Title:	Colorectal cancer molecular classification using BRAF, KRAS, microsatellite instability and CIMP status: Prognostic implications and response to chemotherapy.
Author:	Murcia, Oscar\|Juarez, Miriam\|Rodriguez-Soler, Maria\|Hernandez-Illan, Eva\|Giner-Calabuig, Mar\|Alustiza, Miren\|Egoavil, Cecilia\|Castillejo, Adela\|Alenda, Cristina\|Barbera, Victor\|Mangas-Sanjuan, Carolina\|Yuste, Ana\|Bujanda, Luis\|Clofent, Joan\|Andreu, Montse
PMID:	30188916

2008.
Journal:	Gastroenterology Res. 2018 Oct;11(5):355-360.
Title:	Clinical, Histologic, and Immunophenotypic Features of Serrated Polyps in Patients With Inflammatory Bowel Disease.
Author:	Yang, Chen\|Tarabishy, Yaman\|Dassopoulos, Themistocles\|Nalbantoglu, ILKe
PMID:	30344807

2009.
Journal:	BMC Cancer. 2018 Oct 19;18(1):998.
Title:	Genetic and immunological biomarkers predict metastatic disease recurrence in stage III colon cancer.
Author:	Sperlich, Andreas\|Balmert, Alexander\|Doll, Dietrich\|Bauer, Sabine\|Franke, Fabian\|Keller, Gisela\|Wilhelm, Dirk\|Mur, Anna\|Respondek, Michael\|Friess, Helmut\|Nitsche, Ulrich\|Janssen, Klaus-Peter
PMID:	30340556

2010.
Journal:	Ann Oncol. 2018 Oct 18. pii: 5136414.
Title:	Biomarker analysis beyond angiogenesis: RAS/RAF mutation status, tumour sidedness, and second-line ramucirumab efficacy in patients with metastatic colorectal carcinoma from RAISE, a global phase 3 study.
Author:	Yoshino, T\|Portnoy, D C\|Obermannova, R\|Bodoky, G\|Prausova, J\|Garcia-Carbonero, R\|Ciuleanu, T\|Garcia-Alfonso, P\|Cohn, A L\|Van Cutsem, E\|Yamazaki, K\|Lonardi, S\|Muro, K\|Kim, T W\|Yamaguchi, K\|Grothey, A\|O'Connor, J\|Taieb, J\|Wijayawardana, S R\|Hozak, R R\|Nasro
PMID:	30339194

2011.
Journal:	Clin Lab. 2018 Oct 1;64(10):1719-1730.
Title:	Early Detection of Colorectal Cancer: a Multi-Center Pre-Clinical Case Cohort Study for Validation of a Combined DNA Stool Test.
Author:	Dollinger, Matthias M\|Behl, Susanna\|Fleig, Wolfgang E
PMID:	30336540

2012.
Journal:	Ther Drug Monit. 2018 Oct 16.
Title:	Circulating cell-free DNA- diagnostic and prognostic applications in personalized cancer therapy.
Author:	Oellerich, M\|Schutz, E\|Beck, J\|Walson, P D
PMID:	30335711

2013.
Journal:	Oncol Lett. 2018 Nov;16(5):6188-6194.
Title:	EPA significantly improves anti-EGFR targeted therapy by regulating miR-378 expression in colorectal cancer.
Author:	Weng, Wen-Hui\|Leung, Wai-Hung\|Pang, Yeu Jye\|Kuo, Li-Wei\|Hsu, Hsi-Hsien
PMID:	30333883

2014.
Journal:	J Cell Biochem. 2018 Oct 15.
Title:	Signal transducer and activator of transcription 3 inhibition enhances vemurafenib sensitivity in colon cancers harboring the BRAF(V600E) mutation.
Author:	Wang, Kai\|Li, Yanrong\|Song, Na\|Che, Xiaofang\|Hou, Kezuo\|Xu, Ling\|Bai, Ming\|Wang, Qiwei\|Wang, Yuanhe\|Zhou, Yang\|Cao, Meihui\|Liu, Yunpeng\|Zhang, Jingdong
PMID:	30320916

2015.
Journal:	J Clin Pathol. 2018 Oct 12. pii: jclinpath-2018-205412.
Title:	Evaluation of a novel liquid biopsy-based ColoScape assay for mutational analysis of colorectal neoplasia and triage of FIT+ patients: a pilot study.
Author:	Scimia, Mauro\|Du, Jinwei\|Pepe, Francesco\|Bianco, Maria Antonia\|Russo Spena, Silvana\|Patell-Socha, Farah\|Sun, Qing\|Powell, Michael J\|Malapelle, Umberto\|Troncone, Giancarlo
PMID:	30315134

2016.
Journal:	Clin Colorectal Cancer. 2018 Aug 11. pii: S1533-0028(18)30272-X.
Title:	ACTH-Secreting Neuroendocrine Carcinoma of the Cecum: Case Report and Review of the Literature.
Author:	Mokhtar, Ahmed\|Arnason, Thomas\|Gaston, Daniel\|Huang, Weei-Yuarn\|MacKenzie, Heather\|Al-Hazmi, Rayan\|Vaninetti, Nadine\|Tugwell, Barna\|Rayson, Daniel
PMID:	30314823

2017.
Journal:	Am J Surg Pathol. 2018 Oct;42(10):1409-1417.
Title:	Loss of SATB2 Expression in Colorectal Carcinoma Is Associated With DNA Mismatch Repair Protein Deficiency and BRAF Mutation.
Author:	Ma, Changqing\|Olevian, Dane C\|Lowenthal, Brett M\|Jayachandran, Priya\|Kozak, Margaret M\|Chang, Daniel T\|Pai, Reetesh K
PMID:	30001238

2018.
Journal:	Genet Test Mol Biomarkers. 2018 Aug;22(8):492-497.
Title:	The First Molecular Screening of MLH1 and MSH2 Genes in Moroccan Colorectal Cancer Patients Shows a Relatively High Mutational Prevalence.
Author:	Moufid, Fatima Zahra\|Bouguenouch, Laila\|El Bouchikhi, Ihssane\|Chbani, Laila\|Iraqui Houssaini, Mohamed\|Sekal, Mohamed\|Belhassan, Khadija\|Bennani, Bahia\|Ouldim, Karim
PMID:	30044143

2019.
Journal:	Lancet Gastroenterol Hepatol. 2018 Sep;3(9):635-643.
Title:	Mutation burden and other molecular markers of prognosis in colorectal cancer treated with curative intent: results from the QUASAR 2 clinical trial and an Australian community-based series.
Author:	Domingo, Enric\|Camps, Carme\|Kaisaki, Pamela J\|Parsons, Marie J\|Mouradov, Dmitri\|Pentony, Melissa M\|Makino, Seiko\|Palmieri, Michelle\|Ward, Robyn L\|Hawkins, Nicholas J\|Gibbs, Peter\|Askautrud, Hanne\|Oukrif, Dahmane\|Wang, Haitao\|Wood, Joe\|Tomlinson, Evie\|Bark
PMID:	30042065

2020.
Journal:	Eur J Cancer. 2018 Sep;101:105-113.
Title:	Impact of primary tumour location and RAS/BRAF mutational status in metastatic colorectal cancer treated with first-line regimens containing oxaliplatin and bevacizumab: Prognostic factors from the AIO KRK0207 first-line and maintenance therapy trial.
Author:	Hegewisch-Becker, Susanna\|Nopel-Dunnebacke, Stefanie\|Hinke, Axel\|Graeven, Ullrich\|Reinacher-Schick, Anke\|Hertel, Jan\|Lerchenmuller, Christian A\|Killing, Birgitta\|Depenbusch, Reinhard\|Al-Batran, Salah-Eddin\|Lange, Thoralf\|Dietrich, Georg\|Tannapfel, Andrea\|
PMID:	30036739

2021.
Journal:	Am J Pathol. 2018 Oct;188(10):2236-2250.
Title:	Expression Profile of LGR5 and Its Prognostic Significance in Colorectal Cancer Progression.
Author:	Jang, Bo Gun\|Kim, Hye Sung\|Chang, Weon Young\|Bae, Jeong Mo\|Kim, Woo Ho\|Kang, Gyeong Hoon
PMID:	30036518

2022.
Journal:	Cancer Biol Ther. 2018 Jul 23:1-4.
Title:	Unusually long-term responses to vemurafenib in BRAF V600E mutated colon and thyroid cancers followed by the development of rare RAS activating mutations.
Author:	Ofir Dovrat, Tali\|Sokol, Ethan\|Frampton, Garrett\|Shachar, Eliya\|Pelles, Sharon\|Geva, Ravit\|Wolf, Ido
PMID:	30036146

2023.
Journal:	Acta Oncol. 2018 Jul 23:1-7.
Title:	The survival outcome of patients with metastatic colorectal cancer based on the site of metastases and the impact of molecular markers and site of primary cancer on metastatic pattern.
Author:	Prasanna, Thiru\|Karapetis, Christos S\|Roder, David\|Tie, Jeanne\|Padbury, Robert\|Price, Timothy\|Wong, Rachel\|Shapiro, Jeremy\|Nott, Louise\|Lee, Margaret\|Chua, Yu Jo\|Craft, Paul\|Piantadosi, Cynthia\|Sorich, Michael\|Gibbs, Peter\|Yip, Desmond
PMID:	30035653

2024.
Journal:	BMC Cancer. 2018 Jul 20;18(1):752.
Title:	Genomic alterations accompanying tumour evolution in colorectal cancer: tracking the differences between primary tumours and synchronous liver metastases by whole-exome sequencing.
Author:	Mogensen, M B\|Rossing, M\|Ostrup, O\|Larsen, P N\|Heiberg Engel, P J\|Jorgensen, L N\|Hogdall, E V\|Eriksen, J\|Ibsen, P\|Jess, P\|Grauslund, M\|Nielsen, H J\|Nielsen, F C\|Vainer, B\|Osterlind, K
PMID:	30029640

2025.
Journal:	Cancer Res. 2018 Sep 1;78(17):5164-5172.
Title:	A Rare Missense Variant in TCF7L2 Associates with Colorectal Cancer Risk by Interacting with a GWAS-Identified Regulatory Variant in the MYC Enhancer.
Author:	Chang, Jiang\|Tian, Jianbo\|Yang, Yang\|Zhong, Rong\|Li, Jiaoyuan\|Zhai, Kan\|Ke, Juntao\|Lou, Jiao\|Chen, Wei\|Zhu, Beibei\|Shen, Na\|Zhang, Yi\|Gong, Yajie\|Zhu, Ying\|Zou, Danyi\|Peng, Xiating\|Huang, Kun\|Miao, Xiaoping
PMID:	30026326

2026.
Journal:	Expert Rev Anticancer Ther. 2018 Oct;18(10):991-1006.
Title:	Targeted therapy for metastatic colorectal cancer.
Author:	Price, Timothy J\|Tang, Monica\|Gibbs, Peter\|Haller, Daniel G\|Peeters, Marc\|Arnold, Dirk\|Segelov, Eva\|Roy, Amitesh\|Tebbutt, Niall\|Pavlakis, Nick\|Karapetis, Chris\|Burge, Matthew\|Shapiro, Jeremy
PMID:	30019590

2027.
Journal:	Exp Mol Pathol. 2018 Aug;105(1):153-159.
Title:	Immunohistochemistry is a feasible method to screen BRAF V600E mutation in colorectal and papillary thyroid carcinoma.
Author:	Zhang, Xiangyan\|Wang, Lili\|Wang, Jigang\|Zhao, Han\|Wu, Jie\|Liu, Shuhong\|Zhang, Lu\|Li, Yujun\|Xing, Xiaoming
PMID:	30009773

2028.
Journal:	Virchows Arch. 2018 Oct;473(4):413-423.
Title:	HER2 status in patients with residual rectal cancer after preoperative chemoradiotherapy: the relationship with molecular results and clinicopathologic features.
Author:	Park, Jun Seok\|Yoon, Ghilsuk\|Kim, Hye Jin\|Park, Soo Yeun\|Choi, Gyu Seog\|Kang, Min Kyu\|Kim, Jong Gwang\|Jang, Jung-Sik\|Seo, An Na
PMID:	30056472

2029.
Journal:	Zhonghua Bing Li Xue Za Zhi. 2018 Jul 8;47(7):499-504.
Title:	[Feasibility of amplicon-based targeted next-generation sequencing of colorectal cancer in endoscopic biopsies].
Author:	Wang, Y J\|Jiang, R R\|Liu, H J\|Zhang, B\|Ye, F\|Bu, H
PMID:	29996313

2030.
Journal:	Br J Cancer. 2018 Jul 10. pii: 10.1038/s41416-018-0174-y.
Title:	ERK and p38MAPK combine to improve survival in patients with BRAF mutant colorectal cancer.
Author:	Roseweir, Antonia K\|Halcrow, Elaine S\|Chichilo, Sergey\|Powell, Arfon Gmt\|McMillan, Donald C\|Horgan, Paul G\|Edwards, Joanne
PMID:	29988110

2031.
Journal:	Appl Immunohistochem Mol Morphol. 2018 Jul 5.
Title:	Colorectal Cancer Stratification in the Routine Clinical Pathway: A District General Hospital Experience.
Author:	Wedden, Sarah\|Miller, Keith\|Frayling, Ian M\|Thomas, Teresa\|Chefani, Alina\|Miller, Karolina\|Hamblin, Angela\|Taylor, Jenny C\|D'Arrigo, Corrado
PMID:	29985199

2032.
Journal:	World J Surg Oncol. 2018 Jul 5;16(1):128.
Title:	Differences in gene mutations according to gender among patients with colorectal cancer.
Author:	Tsai, Yi-Jian\|Huang, Sheng-Chieh\|Lin, Hung-Hsin\|Lin, Chun-Chi\|Lan, Yuan-Tzu\|Wang, Huann-Sheng\|Yang, Shung-Haur\|Jiang, Jeng-Kai\|Chen, Wei-Shone\|Lin, Tzu-Chen\|Lin, Jen-Kou\|Chang, Shih-Ching
PMID:	29976257

2033.
Journal:	Mol Cell Proteomics. 2018 Oct;17(10):1892-1908.
Title:	A System-wide Approach to Monitor Responses to Synergistic BRAF and EGFR Inhibition in Colorectal Cancer Cells.
Author:	Ressa, Anna\|Bosdriesz, Evert\|de Ligt, Joep\|Mainardi, Sara\|Maddalo, Gianluca\|Prahallad, Anirudh\|Jager, Myrthe\|de la Fonteijne, Lisanne\|Fitzpatrick, Martin\|Groten, Stijn\|Altelaar, A F Maarten\|Bernards, Rene\|Cuppen, Edwin\|Wessels, Lodewyk\|Heck, Albert J R
PMID:	29970458

2034.
Journal:	Zhonghua Wei Chang Wai Ke Za Zhi. 2018 Jun 25;21(6):716-720.
Title:	[Impacts of microsatellite status, RAS and BRAF mutation on postoperative follow-up strategy in stage II( and III( colorectal cancer].
Author:	Zhang, Jing\|Wang, Xicheng\|Shen, Lin
PMID:	29968248

2035.
Journal:	Clin Gastroenterol Hepatol. 2018 Jun 30. pii: S1542-3565(18)30695-5.
Title:	Evaluating the Combination of Microsatellite Instability and Mutation in BRAF as Prognostic Factors for Patients With Colorectal Cancer.
Author:	Sinicrope, Frank A
PMID:	29966708

2036.
Journal:	J Mol Diagn. 2018 Sep;20(5):664-676.
Title:	Multicenter Evaluation of the Idylla NRAS-BRAF Mutation Test in Metastatic Colorectal Cancer.
Author:	Prieto-Potin, Ivan\|Montagut, Clara\|Bellosillo, Beatriz\|Evans, Matthew\|Smith, Matthew\|Melchior, Linea\|Reiltin, Werner\|Bennett, Michael\|Pennati, Veronica\|Castiglione, Francesca\|Burrig, Karl-Friedrich\|Cooper, Ulrike\|Dockhorn-Dworniczak, Barbara\|Rossenbach, C
PMID:	29959022

2037.
Journal:	Mod Pathol. 2018 Jun 28. pii: 10.1038/s41379-018-0094-7.
Title:	Assessing colorectal cancer mismatch repair status in the modern era: a survey of current practices and re-evaluation of the role of microsatellite instability testing.
Author:	Hissong, Erika\|Crowe, Elizabeth P\|Yantiss, Rhonda K\|Chen, Yao-Tseng
PMID:	29955148

2038.
Journal:	Oncol Rep. 2018 Oct;40(4):2171-2182.
Title:	Inhibition of YAP reverses primary resistance to EGFR inhibitors in colorectal cancer cells.
Author:	Liu, Bi-Sheng\|Xia, Hong-Wei\|Zhou, Sheng\|Liu, Qing\|Tang, Qiu-Lin\|Bi, Na-Xi\|Zhou, Ji-Tao\|Gong, Qi-Yong\|Nie, Yong-Zhan\|Bi, Feng
PMID:	30106444

2039.
Journal:	J Natl Compr Canc Netw. 2018 Sep;16(9):1035-1040.
Title:	Targeting BRAF Mutations in High-Grade Neuroendocrine Carcinoma of the Colon.
Author:	Burkart, Jarred\|Owen, Dwight\|Shah, Manisha H\|Abdel-Misih, Sherif R Z\|Roychowdhury, Sameek\|Wesolowski, Robert\|Haraldsdottir, Sigurdis\|Reeser, Julie W\|Samorodnitsky, Eric\|Smith, Amy\|Konda, Bhavana
PMID:	30181415

2040.
Journal:	J Cancer Res Clin Oncol. 2018 Aug 31. pii: 10.1007/s00432-018-2742-1.
Title:	The gene mutational discrepancies between primary and paired metastatic colorectal carcinoma detected by next-generation sequencing.
Author:	Zou, Shuang-Mei\|Li, Wei-Hua\|Wang, Wen-Miao\|Li, Wen-Bin\|Shi, Su-Sheng\|Ying, Jian-Ming\|Lyu, Ning
PMID:	30171333

2041.
Journal:	Trans Am Clin Climatol Assoc. 2018;129:56-62.
Title:	MOLECULAR FEATURES AND MOUSE MODELS OF COLORECTAL CANCER.
Author:	Fearon, Eric R
PMID:	30166699

2042.
Journal:	BMJ Open. 2018 Aug 30;8(8):e023102.
Title:	Prevalence and clinicopathological characteristics of mismatch repair-deficient colorectal carcinoma in early onset cases as compared with late-onset cases: a retrospective cross-sectional study in Northeastern Iran.
Author:	Goshayeshi, Ladan\|Ghaffarzadegan, Kamran\|Khooei, Alireza\|Esmaeilzadeh, Abbas\|Rahmani Khorram, Mahla\|Mosannen Mozaffari, Hooman\|Kiani, Behzad\|Hoseini, Benyamin
PMID:	30166308

2043.
Journal:	Mol Carcinog. 2018 Aug 29.
Title:	EXOSC4 functions as a potential oncogene in development and progression of colorectal cancer.
Author:	Pan, Yi\|Tong, Joanna H M\|Kang, Wei\|Lung, Raymond W M\|Chak, Wing Po\|Chung, Lau Ying\|Wu, Feng\|Li, Hui\|Yu, Jun\|Chan, Anthony W H\|To, Ka Fai
PMID:	30155936

2044.
Journal:	Contemp Oncol (Pozn). 2018;22(2):75-85.
Title:	Quality and practical aspects of pathological and molecular diagnostics in metastatic colorectal cancer (mCRC).
Author:	Tysarowski, Andrzej\|Nasierowska-Guttmejer, Anna
PMID:	30150883

2045.
Journal:	Clin Colorectal Cancer. 2018 Jul 25. pii: S1533-0028(18)30267-6.
Title:	Impact of the Localization of the Primary Tumor and RAS/BRAF Mutational Status on Maintenance Strategies After First-line Oxaliplatin, Fluoropyrimidine, and Bevacizumab in Metastatic Colorectal Cancer: Results From the AIO 0207 Trial.
Author:	Noepel-Duennebacke, Stefanie\|Arnold, Dirk\|Hertel, Jan\|Tannapfel, Andrea\|Hinke, Axel\|Hegewisch-Becker, Susanna\|Reinacher-Schick, Anke
PMID:	30145148

2046.
Journal:	Aging (Albany NY). 2018 Aug 22;10(8):2062-2078.
Title:	LncRNA BANCR promotes tumorigenesis and enhances adriamycin resistance in colorectal cancer.
Author:	Ma, Siping\|Yang, Dongxiang\|Liu, Yanlong\|Wang, Yongpeng\|Lin, Tao\|Li, Yanxi\|Yang, Shihua\|Zhang, Wanchuan\|Zhang, Rui
PMID:	30144787

2047.
Journal:	Cancer Manag Res. 2018 Aug 1;10:2289-2301.
Title:	Development of small-molecule therapeutics and strategies for targeting RAF kinase in BRAF-mutant colorectal cancer.
Author:	Pan, Jing-Hua\|Zhou, Hong\|Zhu, Sheng-Bin\|Huang, Jin-Lian\|Zhao, Xiao-Xu\|Ding, Hui\|Pan, Yun-Long
PMID:	30122982

2048.
Journal:	BMC Cancer. 2018 Jun 27;18(1):695.
Title:	Gene promoter and exon DNA methylation changes in colon cancer development - mRNA expression and tumor mutation alterations.
Author:	Molnar, Bela\|Galamb, Orsolya\|Peterfia, Balint\|Wichmann, Barnabas\|Csabai, Istvan\|Bodor, Andras\|Kalmar, Alexandra\|Szigeti, Krisztina Andrea\|Bartak, Barbara Kinga\|Nagy, Zsofia Brigitta\|Valcz, Gabor\|Patai, Arpad V\|Igaz, Peter\|Tulassay, Zsolt
PMID:	29945573

2049.
Journal:	Curr Probl Cancer. 2018 Jul 19. pii: S0147-0272(17)30139-3.
Title:	HER2: An emerging target in colorectal cancer.
Author:	Greally, Megan\|Kelly, Ciara M\|Cercek, Andrea
PMID:	30100092

2050.
Journal:	World J Gastroenterol. 2018 Aug 7;24(29):3250-3259.
Title:	Endoscopic diagnosis of sessile serrated adenoma/polyp with and without dysplasia/carcinoma.
Author:	Murakami, Takashi\|Sakamoto, Naoto\|Nagahara, Akihito
PMID:	30090005

2051.
Journal:	Sci Rep. 2018 Aug 7;8(1):11797.
Title:	The atypical cyclin CNTD2 promotes colon cancer cell proliferation and migration.
Author:	Sanchez-Botet, Abril\|Gasa, Laura\|Quandt, Eva\|Hernandez-Ortega, Sara\|Jimenez, Javier\|Mezquita, Pau\|Carrasco-Garcia, Miquel Angel\|Kron, Stephen J\|Vidal, August\|Villanueva, Alberto\|Ribeiro, Mariana P C\|Clotet, Josep
PMID:	30087414

2052.
Journal:	Adv Clin Exp Med. 2018 Aug 7.
Title:	Analysis of KRAS, NRAS, BRAF, and PIK3CA mutations could predict metastases in colorectal cancer: A preliminary study.
Author:	Wojas-Krawczyk, Kamila\|Kalinka-Warzocha, Ewa\|Reszka, Katarzyna\|Nicos, Marcin\|Szumilo, Justyna\|Mandziuk, Slawomir\|Szczepaniak, Katarzyna\|Kupnicka, Dorota\|Lewandowski, Remigiusz\|Milanowski, Janusz\|Krawczyk, Pawel
PMID:	30085422

2053.
Journal:	ChemMedChem. 2018 Sep 19;13(18):1895-1908.
Title:	Synthesis, Computational Docking Study, and Biological Evaluation of a Library of Heterocyclic Curcuminoids with Remarkable Antitumor Activity.
Author:	Laali, Kenneth K\|Greves, William J\|Zwarycz, Angela T\|Correa Smits, Sebastian J\|Troendle, Frederick J\|Borosky, Gabriela L\|Akhtar, Sharoon\|Manna, Alak\|Paulus, Aneel\|Chanan-Khan, Asher\|Nukaya, Manabu\|Kennedy, Gregory D
PMID:	30079563

2054.
Journal:	Ann Saudi Med. 2018 Jul-Aug;38(4):251-259.
Title:	Molecular characteristics of colorectal cancer in a Middle Eastern population in a single institution.
Author:	Ibrahim, Tony\|Saer-Ghorra, Claude\|Trak-Smayra, Vivane\|Nadiri, Samah\|Yazbeck, Charbel\|Baz, Maria\|Kattan, Joseph G
PMID:	30078023

2055.
Journal:	Microrna. 2018 Aug 2. pii: MIRNA-EPUB-92141.
Title:	Computational Analysis of miRNA and their Gene Targets Significantly Involved in Colorectal Cancer Progression.
Author:	Kandhavelu, Jeyalakshmi\|Subramanian, Kumar\|Khan, Amber\|Omar, Aadilah\|Ruff, Paul\|Penny, Clement
PMID:	30073936

2056.
Journal:	Transl Oncol. 2018 Oct;11(5):1188-1201.
Title:	Clinical, Pathological, and Molecular Characteristics of CpG Island Methylator Phenotype in Colorectal Cancer: A Systematic Review and Meta-analysis.
Author:	Advani, Shailesh M\|Advani, Pragati\|DeSantis, Stacia M\|Brown, Derek\|VonVille, Helena M\|Lam, Michael\|Loree, Jonathan M\|Mehrvarz Sarshekeh, Amir\|Bressler, Jan\|Lopez, David S\|Daniel, Carrie R\|Swartz, Michael D\|Kopetz, Scott
PMID:	30071442

2057.
Journal:	Recent Results Cancer Res. 2018;211:77-89.
Title:	Vemurafenib.
Author:	Garbe, Claus\|Eigentler, Thomas K
PMID:	30069761