Primary Site >> Colorectal Cancer

Gene >> BNIP3

Journal: Int J Cancer. 2000 Aug 20;90(4):175-85.
Title: Survival of colorectal cancer cell lines treated with paclitaxel, radiation, and 5-FU: effect of TP53 or hMLH1 deficiency.
Author: Kennedy, A S|Harrison, G H|Mansfield, C M|Zhou, X J|Xu, J F|Balcer-Kubiczek, E K
PMID: 10993958
Journal: Carcinogenesis. 2002 Dec;23(12):2063-80.
Title: Development and molecular characterization of HCT-116 cell lines resistant to the tumor promoter and multiple stress-inducer, deoxycholate.
Author: Crowley-Weber, Cara L|Payne, Claire M|Gleason-Guzman, Mary|Watts, George S|Futscher, Bernard|Waltmire, Caroline N|Crowley, Cheray|Dvorakova, Katerina|Bernstein, Carol|Craven, Mary|Garewal, Harinder|Bernstein, Harris
PMID: 12507930
Journal: Int J Oncol. 2004 May;24(5):1279-88.
Title: Molecular characterizations of derivatives of HCT116 colorectal cancer cells that are resistant to the chemotherapeutic agent 5-fluorouracil.
Author: de Angelis, Paula M|Fjell, Bjorg|Kravik, Katherine L|Haug, Terje|Tunheim, Siv H|Reichelt, Wenche|Beigi, Marzieh|Clausen, Ole Petter|Galteland, Eivind|Stokke, Trond
PMID: 15067352
Journal: Ann Surg Oncol. 2004 Feb;11(2):192-6.
Title: Deleted in oral cancer-1 expression upregulates proapoptosis elements in microsatellite-unstable human colorectal cancer.
Author: Sotsky Kent, Tara|Yuan, Ziqiang|Miller, Agnes|Weber, Thomas K
PMID: 14761923
Journal: Photochem Photobiol. 2005 Mar-Apr;81(2):306-13.
Title: Alterations in mitochondrial and apoptosis-regulating gene expression in photodynamic therapy-resistant variants of HT29 colon carcinoma cells.
Author: Shen, Xiao Yun|Zacal, Natalie|Singh, Gurmit|Rainbow, Andrew J
PMID: 15560738
Journal: Biochem Biophys Res Commun. 2005 Jun 3;331(2):648-57.
Title: Increased BNip3 and decreased mutant p53 in cisplatin-sensitive PDT-resistant HT29 cells.
Author: Zacal, Natalie|Espiritu, Myrna|Singh, Gurmit|Rainbow, Andrew J
PMID: 15850808
Journal: Cancer Sci. 2006 Jul;97(7):582-8.
Title: Endogenous markers of hypoxia/anaerobic metabolism and anemia in primary colorectal cancer.
Author: Koukourakis, Michael I|Giatromanolaki, Alexandra|Polychronidis, Alexandros|Simopoulos, Costantinos|Gatter, Kevin C|Harris, Adrian L|Sivridis, Efthimios
PMID: 16827797
Journal: Oncogene. 2007 Jan 4;26(1):132-41. Epub 2006 Jun 26.
Title: Selective silencing of the hypoxia-inducible factor 1 target gene BNIP3 by histone deacetylation and methylation in colorectal cancer.
Author: Bacon, A L|Fox, S|Turley, H|Harris, A L
PMID: 16799636
Journal: Ann Surg Oncol. 2007 May;14(5):1752-62.
Title: Effect of combined therapy with low-dose 5-aza-2'-deoxycytidine and irinotecan on colon cancer cell line HCT-15.
Author: Ishiguro, Megumi|Iida, Satoru|Uetake, Hiroyuki|Morita, Shinji|Makino, Hiroshi|Kato, Keiji|Takagi, Yoko|Enomoto, Masayuki|Sugihara, Kenichi
PMID: 17195906
Journal: Photochem Photobiol. 2007 May-Jun;83(3):730-7.
Title: Photodynamic therapy resistant human colon carcinoma HT29 cells show cross-resistance to UVA but not UVC light.
Author: Zacal, Natalie|Rainbow, Andrew J
PMID: 17576382
Journal: Anticancer Drugs. 2007 Jul;18(6):633-9.
Title: Establishment and gene analysis of an oxaliplatin-resistant colon cancer cell line THC8307/L-OHP.
Author: Tang, Hua|Liu, Yuan-Jun|Liu, Min|Li, Xin
PMID: 17762391
Journal: J Cell Mol Med. 2008 Jun;12(3):1005-22.
Title: Brevinin-2R(1) semi-selectively kills cancer cells by a distinct mechanism, which involves the lysosomal-mitochondrial death pathway.
Author: Ghavami, Saeid|Asoodeh, Ahmad|Klonisch, Thomas|Halayko, Andrew J|Kadkhoda, Kamran|Kroczak, Tadeusz J|Gibson, Spencer B|Booy, Evan P|Naderi-Manesh, Hossein|Los, Marek
PMID: 18494941
Journal: Br J Cancer. 2008 Sep 2;99(5):727-33.
Title: Poorer outcome in stromal HIF-2 alpha- and CA9-positive colorectal adenocarcinomas is associated with wild-type TP53 but not with BNIP3 promoter hypermethylation or apoptosis.
Author: Cleven, A H G|Wouters, B G|Schutte, B|Spiertz, A J G|van Engeland, M|de Bruine, A P
PMID: 18728663
Journal: Cancer Res. 2009 Aug 15;69(16):6423-9.
Title: Epigenetic repression of DNA mismatch repair by inflammation and hypoxia in inflammatory bowel disease-associated colorectal cancer.
Author: Edwards, Robert A|Witherspoon, Mavee|Wang, Kehui|Afrasiabi, Kambiz|Pham, Trang|Birnbaumer, Lutz|Lipkin, Steven M
PMID: 19638594
Journal: Int J Cancer. 2010 Feb 1;126(3):756-63.
Title: Evidence for the contribution of insulin resistance to the development of cachexia in tumor-bearing mice.
Author: Asp, Michelle L|Tian, Min|Wendel, Angela A|Belury, Martha A
PMID: 19634137
Journal: Oncol Rep. 2010 Jan;23(1):191-7.
Title: CpG island methylation of BNIP3 predicts resistance against S-1/CPT-11 combined therapy in colorectal cancer patients.
Author: Hiraki, Masatsugu|Kitajima, Yoshihiko|Nakafusa, Yuji|Nakamura, Jun|Hashiguchi, Kazuyoshi|Sumi, Kenji|Noshiro, Hirokazu|Miyazaki, Kohji
PMID: 19956881
Journal: Endocr Relat Cancer. 2010 Jun 1;17(2):351-60.
Title: Metformin blocks the stimulative effect of a high-energy diet on colon carcinoma growth in vivo and is associated with reduced expression of fatty acid synthase.
Author: Algire, Carolyn|Amrein, Lilian|Zakikhani, Mahvash|Panasci, Lawrence|Pollak, Michael
PMID: 20228137
Journal: Sichuan Da Xue Xue Bao Yi Xue Ban. 2010 Nov;41(6):975-9.
Title: [Effect and mechanism of DNMT inhibitor on the reversal of multidrug resistance in human colon cancer cell line sw620/L-OHP].
Author: Deng, Qian|Li, Zhi-ping|Huang, Chun-mei|Liu, Zhen|Zhong, Ren-ming|Li, Ai-jun|Bi, Feng|Tang, Qiu-lin
PMID: 21265097
Journal: Oncol Lett. 2010 Sep;1(5):865-872.
Title: Methylated BNIP3 gene in colorectal cancer prognosis.
Author: Shimizu, Sayaka|Iida, Satoru|Ishiguro, Megumi|Uetake, Hiroyuki|Ishikawa, Toshiaki|Takagi, Yoko|Kobayashi, Hirotoshi|Higuchi, Tetsuro|Enomoto, Masayuki|Mogushi, Kaoru|Mizushima, Hiroshi|Tanaka, Hiroshi|Sugihara, Kenichi
PMID: 22966396
Journal: Cancer Res. 2011 Nov 1;71(21):6807-16.
Title: Verticillin A overcomes apoptosis resistance in human colon carcinoma through DNA methylation-dependent upregulation of BNIP3.
Author: Liu, Feiyan|Liu, Qianqian|Yang, Dafeng|Bollag, Wendy B|Robertson, Keith|Wu, Ping|Liu, Kebin
PMID: 21911457
Journal: Oncology. 2012;82(3):153-64.
Title: Differential expression of senescence and cell death factors in non-small cell lung and colorectal tumors showing telomere attrition.
Author: Fernandez-Marcelo, Tamara|Moran, Alberto|de Juan, Carmen|Pascua, Irene|Head, Jacqueline|Gomez, Ana|Hernando, Florentino|Lopez-Asenjo, Jose A|Hernandez, Susana|Sanchez-Pernaute, Andres|Torres, Antonio J|Benito, Manuel|Iniesta, Pilar
PMID: 22433385
Journal: J Immunol. 2012 May 1;188(9):4441-9.
Title: Decitabine and vorinostat cooperate to sensitize colon carcinoma cells to Fas ligand-induced apoptosis in vitro and tumor suppression in vivo.
Author: Yang, Dafeng|Torres, Christina M|Bardhan, Kankana|Zimmerman, Mary|McGaha, Tracy L|Liu, Kebin
PMID: 22461695
Journal: Oncol Lett. 2012 Mar;3(3):565-570.
Title: PIK3CA mutation and methylation influences the outcome of colorectal cancer.
Author: Iida, Satoru|Kato, Shunsuke|Ishiguro, Megumi|Matsuyama, Takatoshi|Ishikawa, Toshiaki|Kobayashi, Hirotoshi|Higuchi, Tetsuro|Uetake, Hiroyuki|Enomoto, Masayuki|Sugihara, Kenichi
PMID: 22740953
Journal: Oncol Lett. 2012 Dec;4(6):1195-1202.
Title: Effects of the proapoptotic regulator Bcl-2/adenovirus EIB 19-kDa-interacting protein 3 on the chemosensitivity of human colon cancer cell lines.
Author: Wang, Zi|Huang, Chunmei|Zeng, Jianshuang|Deng, Qian|Zeng, Hui|Liu, Zhen|Peng, Xingchen|Bi, Feng|Tang, Qiulin|Li, Zhiping
PMID: 23205118
Journal: Chemotherapy. 2012;58(6):445-53.
Title: Chemotherapy and radiotherapy downregulate the activity and expression of DNA methyltransferase and enhance Bcl-2/E1B-19-kDa interacting protein-3-induced apoptosis in human colorectal cancer cells.
Author: Deng, Qian|Huang, Chun-mei|Chen, Ni|Li, Li|Wang, Xiao-dong|Zhang, Wen|Bi, Feng|Tang, Qiu-lin|Li, Zhi-ping|Wang, Wei
PMID: 23364257
Journal: Gut. 2012 Nov;61(11):1560-7.
Title: ColoGuideEx: a robust gene classifier specific for stage II colorectal cancer prognosis.
Author: Agesen, Trude H|Sveen, Anita|Merok, Marianne A|Lind, Guro E|Nesbakken, Arild|Skotheim, Rolf I|Lothe, Ragnhild A
PMID: 22213796
Journal: Food Chem. 2013 Jun 1;138(2-3):1172-82.
Title: Hydroxytyrosyl ethyl ether exhibits stronger intestinal anticarcinogenic potency and effects on transcript profiles compared to hydroxytyrosol.
Author: Pereira-Caro, G|Mateos, R|Traka, M H|Bacon, J R|Bongaerts, R|Sarria, B|Bravo, L|Kroon, P A
PMID: 23411228
Journal: J Agric Food Chem. 2013 Apr 3;61(13):3264-9.
Title: Anticancer activity of olive oil hydroxytyrosyl acetate in human adenocarcinoma Caco-2 cells.
Author: Mateos, Raquel|Pereira-Caro, Gema|Bacon, James R|Bongaerts, Roy|Sarria, Beatriz|Bravo, Laura|Kroon, Paul A
PMID: 23452288
Journal: Biochem Biophys Res Commun. 2013 Nov 29;441(4):707-12.
Title: The interplay between epigenetic silencing, oncogenic KRas and HIF-1 regulatory pathways in control of BNIP3 expression in human colorectal cancer cells.
Author: Swiderek, Ewelina|Kalas, Wojciech|Wysokinska, Edyta|Pawlak, Alicja|Rak, Janusz|Strzadala, Leon
PMID: 24211581
Journal: Front Oncol. 2014 Feb 4;4:10.
Title: Increased Tumor Ascorbate is Associated with Extended Disease-Free Survival and Decreased Hypoxia-Inducible Factor-1 Activation in Human Colorectal Cancer.
Author: Kuiper, Caroline|Dachs, Gabi U|Munn, Delwyn|Currie, Margaret J|Robinson, Bridget A|Pearson, John F|Vissers, Margreet C M
PMID: 24551593
Journal: J Cell Physiol. 2015 Apr;230(4):930-46.
Title: Justicidin A-induced autophagy flux enhances apoptosis of human colorectal cancer cells via class III PI3K and Atg5 pathway.
Author: Won, Shen-Jeu|Yen, Cheng-Hsin|Liu, Hsiao-Sheng|Wu, Shan-Ying|Lan, Sheng-Hui|Jiang-Shieh, Ya-Fen|Lin, Chun-Nan|Su, Chun-Li
PMID: 25216025
Journal: Radiother Oncol. 2015 Sep;116(3):346-51.
Title: The usability of a 15-gene hypoxia classifier as a universal hypoxia profile in various cancer cell types.
Author: Sorensen, Brita Singers|Knudsen, Anders|Wittrup, Catja Foged|Nielsen, Steffen|Aggerholm-Pedersen, Ninna|Busk, Morten|Horsman, Michael|Hoyer, Morten|Bouchelouche, Pierre Nourdine|Overgaard, Jens|Alsner, Jan
PMID: 26169282
Journal: Radiother Oncol. 2015 Sep;116(3):409-16.
Title: AMPK-independent autophagy promotes radioresistance of human tumor cells under clinical relevant hypoxia in vitro.
Author: Chaachouay, Hassan|Fehrenbacher, Birgit|Toulany, Mahmoud|Schaller, Martin|Multhoff, Gabriele|Rodemann, H Peter
PMID: 26318663
Journal: Oncogenesis. 2016 Jan 4;4:e181.
Title: Mieap-regulated mitochondrial quality control is frequently inactivated in human colorectal cancer.
Author: Kamino, H|Nakamura, Y|Tsuneki, M|Sano, H|Miyamoto, Y|Kitamura, N|Futamura, M|Kanai, Y|Taniguchi, H|Shida, D|Kanemitsu, Y|Moriya, Y|Yoshida, K|Arakawa, H
PMID: 26727575
Journal: Cell Physiol Biochem. 2017;41(5):1851-1864.
Title: Osteopontin Promotes Cell Migration and Invasion, and Inhibits Apoptosis and Autophagy in Colorectal Cancer by activating the p38 MAPK Signaling Pathway.
Author: Huang, Ren-Hong|Quan, Ying-Jun|Chen, Jin-Hong|Wang, Ting-Feng|Xu, Ming|Ye, Min|Yuan, Hao|Zhang, Chong-Jie|Liu, Xiao-Jian|Min, Zhi-Jun
PMID: 28376477
Journal: Yonsei Med J. 2017 Jul;58(4):749-755.
Title: Lack of Aberrant Methylation in an Adjacent Area of Left-Sided Colorectal Cancer.
Author: Sambuudash, Otgontuya|Kim, Hyun Soo|Cho, Mee Yon
PMID: 28540987
Journal: Pharm Res. 2017 Sep;34(9):1849-1856.
Title: The Cardiotoxic Mechanism of Doxorubicin (DOX) and Pegylated Liposomal DOX in Mice Bearing C-26 Colon Carcinoma: a Study Focused on microRNA Role for Toxicity Assessment of New Formulations.
Author: Razavi-Azarkhiavi, Kamal|Jaafari, Mahmoud Reza|Abnous, Khalil|Razavi, Bibi Marjan|Jafarian, Amir Hossein|Hassani, Faezeh Vahdati|Shirani, Kobra|Karimi, Gholamreza
PMID: 28560697
Journal: J Cancer. 2017 Apr 9;8(7):1187-1196.
Title: Chemoresistance of colorectal cancer to 5-fluorouracil is associated with silencing of the BNIP3 gene through aberrant methylation.
Author: He, Jianming|Pei, Li|Jiang, Heng|Yang, Weiwen|Chen, Jianfang|Liang, Houjie
PMID: 28607593
Journal: Cell Biol Toxicol. 2018 Aug;34(4):263-277.
Title: Mst1 regulates colorectal cancer stress response via inhibiting Bnip3-related mitophagy by activation of JNK/p53 pathway.
Author: Li, Qi|Qi, Feng|Meng, Xiangchao|Zhu, Chenpei|Gao, Yingtang
PMID: 29063978