Primary Site >> Colorectal Cancer
Gene >> BNIP3
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Ref: Survival of colorectal cancer cell lines treated with paclitaxel, radiation, and 5-FU: effect of TP53 or hMLH1 deficiency. PMID: 10993958 |
Ref: Development and molecular characterization of HCT-116 cell lines resistant to the tumor promoter and multiple stress-inducer, deoxycholate. PMID: 12507930 |
Ref: Deleted in oral cancer-1 expression upregulates proapoptosis elements in microsatellite-unstable human colorectal cancer. PMID: 14761923 Ref: Molecular characterizations of derivatives of HCT116 colorectal cancer cells that are resistant to the chemotherapeutic agent 5-fluorouracil. PMID: 15067352 |
Ref: Alterations in mitochondrial and apoptosis-regulating gene expression in photodynamic therapy-resistant variants of HT29 colon carcinoma cells. PMID: 15560738 Ref: Increased BNip3 and decreased mutant p53 in cisplatin-sensitive PDT-resistant HT29 cells. PMID: 15850808 |
Ref: Endogenous markers of hypoxia/anaerobic metabolism and anemia in primary colorectal cancer. PMID: 16827797 |
Ref: Selective silencing of the hypoxia-inducible factor 1 target gene BNIP3 by histone deacetylation and methylation in colorectal cancer. PMID: 16799636 Ref: Effect of combined therapy with low-dose 5-aza-2'-deoxycytidine and irinotecan on colon cancer cell line HCT-15. PMID: 17195906 Ref: Photodynamic therapy resistant human colon carcinoma HT29 cells show cross-resistance to UVA but not UVC light. PMID: 17576382 Ref: Establishment and gene analysis of an oxaliplatin-resistant colon cancer cell line THC8307/L-OHP. PMID: 17762391 |
Ref: Brevinin-2R(1) semi-selectively kills cancer cells by a distinct mechanism, which involves the lysosomal-mitochondrial death pathway. PMID: 18494941 Ref: Poorer outcome in stromal HIF-2 alpha- and CA9-positive colorectal adenocarcinomas is associated with wild-type TP53 but not with BNIP3 promoter hypermethylation or apoptosis. PMID: 18728663 |
Ref: Epigenetic repression of DNA mismatch repair by inflammation and hypoxia in inflammatory bowel disease-associated colorectal cancer. PMID: 19638594 |
Ref: Evidence for the contribution of insulin resistance to the development of cachexia in tumor-bearing mice. PMID: 19634137 Ref: CpG island methylation of BNIP3 predicts resistance against S-1/CPT-11 combined therapy in colorectal cancer patients. PMID: 19956881 Ref: Metformin blocks the stimulative effect of a high-energy diet on colon carcinoma growth in vivo and is associated with reduced expression of fatty acid synthase. PMID: 20228137 Ref: [Effect and mechanism of DNMT inhibitor on the reversal of multidrug resistance in human colon cancer cell line sw620/L-OHP]. PMID: 21265097 Ref: Methylated BNIP3 gene in colorectal cancer prognosis. PMID: 22966396 |
Ref: Verticillin A overcomes apoptosis resistance in human colon carcinoma through DNA methylation-dependent upregulation of BNIP3. PMID: 21911457 |
Ref: ColoGuideEx: a robust gene classifier specific for stage II colorectal cancer prognosis. PMID: 22213796 Ref: Differential expression of senescence and cell death factors in non-small cell lung and colorectal tumors showing telomere attrition. PMID: 22433385 Ref: Decitabine and vorinostat cooperate to sensitize colon carcinoma cells to Fas ligand-induced apoptosis in vitro and tumor suppression in vivo. PMID: 22461695 Ref: PIK3CA mutation and methylation influences the outcome of colorectal cancer. PMID: 22740953 Ref: Effects of the proapoptotic regulator Bcl-2/adenovirus EIB 19-kDa-interacting protein 3 on the chemosensitivity of human colon cancer cell lines. PMID: 23205118 Ref: Chemotherapy and radiotherapy downregulate the activity and expression of DNA methyltransferase and enhance Bcl-2/E1B-19-kDa interacting protein-3-induced apoptosis in human colorectal cancer cells. PMID: 23364257 |
Ref: Hydroxytyrosyl ethyl ether exhibits stronger intestinal anticarcinogenic potency and effects on transcript profiles compared to hydroxytyrosol. PMID: 23411228 Ref: Anticancer activity of olive oil hydroxytyrosyl acetate in human adenocarcinoma Caco-2 cells. PMID: 23452288 Ref: The interplay between epigenetic silencing, oncogenic KRas and HIF-1 regulatory pathways in control of BNIP3 expression in human colorectal cancer cells. PMID: 24211581 |
Ref: Increased Tumor Ascorbate is Associated with Extended Disease-Free Survival and Decreased Hypoxia-Inducible Factor-1 Activation in Human Colorectal Cancer. PMID: 24551593 |
Ref: Justicidin A-induced autophagy flux enhances apoptosis of human colorectal cancer cells via class III PI3K and Atg5 pathway. PMID: 25216025 Ref: The usability of a 15-gene hypoxia classifier as a universal hypoxia profile in various cancer cell types. PMID: 26169282 Ref: AMPK-independent autophagy promotes radioresistance of human tumor cells under clinical relevant hypoxia in vitro. PMID: 26318663 |
Ref: Mieap-regulated mitochondrial quality control is frequently inactivated in human colorectal cancer. PMID: 26727575 |
Ref: Osteopontin Promotes Cell Migration and Invasion, and Inhibits Apoptosis and Autophagy in Colorectal Cancer by activating the p38 MAPK Signaling Pathway. PMID: 28376477 Ref: Lack of Aberrant Methylation in an Adjacent Area of Left-Sided Colorectal Cancer. PMID: 28540987 Ref: The Cardiotoxic Mechanism of Doxorubicin (DOX) and Pegylated Liposomal DOX in Mice Bearing C-26 Colon Carcinoma: a Study Focused on microRNA Role for Toxicity Assessment of New Formulations. PMID: 28560697 Ref: Chemoresistance of colorectal cancer to 5-fluorouracil is associated with silencing of the BNIP3 gene through aberrant methylation. PMID: 28607593 |
Ref: Mst1 regulates colorectal cancer stress response via inhibiting Bnip3-related mitophagy by activation of JNK/p53 pathway. PMID: 29063978 |