Primary Site >> Colorectal Cancer

Gene >> BMPR2

Journal: Gastroenterology. 2004 Jan;126(1):111-21.
Title: Bone morphogenetic protein 2 is expressed by, and acts upon, mature epithelial cells in the colon.
Author: Hardwick, James C H|Van Den Brink, Gijs R|Bleuming, Sylvia A|Ballester, Isabel|Van Den Brande, Jan M H|Keller, Josbert J|Offerhaus, G Johan A|Van Deventer, Sander J H|Peppelenbosch, Maikel P
PMID: 14699493
Journal: Exp Cell Res. 2007 Mar 10;313(5):1033-44.
Title: Bone morphogenetic protein-4 is overexpressed in colonic adenocarcinomas and promotes migration and invasion of HCT116 cells.
Author: Deng, Haiyun|Makizumi, Ryouji|Ravikumar, T S|Dong, Huali|Yang, Wancai|Yang, Weng-Lang
PMID: 17275810
Journal: Cell Signal. 2007 Aug;19(8):1722-32. Epub 2007 Mar 28.
Title: Proinvasive activity of BMP-7 through SMAD4/src-independent and ERK/Rac/JNK-dependent signaling pathways in colon cancer cells.
Author: Grijelmo, Clara|Rodrigue, Christelle|Svrcek, Magalie|Bruyneel, Erik|Hendrix, An|de Wever, Olivier|Gespach, Christian
PMID: 17478078
Journal: Cancer. 2008 Jan 15;112(2):300-6.
Title: The bone morphogenetic protein pathway is active in human colon adenomas and inactivated in colorectal cancer.
Author: Kodach, Liudmila L|Bleuming, Sylvia A|Musler, Alex R|Peppelenbosch, Maikel P|Hommes, Daniel W|van den Brink, Gijs R|van Noesel, Carel J M|Offerhaus, G Johan A|Hardwick, James C H
PMID: 18008360
Journal: Gastroenterology. 2008 May;134(5):1332-41.
Title: The bone morphogenetic protein pathway is inactivated in the majority of sporadic colorectal cancers.
Author: Kodach, Liudmila L|Wiercinska, Eliza|de Miranda, Noel F C C|Bleuming, Sylvia A|Musler, Alex R|Peppelenbosch, Maikel P|Dekker, Evelien|van den Brink, Gijs R|van Noesel, Carel J M|Morreau, Hans|Hommes, Daniel W|Ten Dijke, Peter|Offerhaus, G Johan A|Hardwick
PMID: 18471510
Journal: APMIS. 2010 Nov;118(11):824-9.
Title: Somatic frameshift mutations of bone morphogenic protein receptor 2 gene in gastric and colorectal cancers with microsatellite instability.
Author: Park, Sang Wook|Hur, Soo Young|Yoo, Nam Jin|Lee, Sug Hyung
PMID: 20955454
Journal: Fam Cancer. 2011 Jun;10(2):245-54.
Title: Linkage to chromosome 2q32.2-q33.3 in familial serrated neoplasia (Jass syndrome).
Author: Roberts, Aedan|Nancarrow, Derek|Clendenning, Mark|Buchanan, Daniel D|Jenkins, Mark A|Duggan, David|Taverna, Darin|McKeone, Diane|Walters, Rhiannon|Walsh, Michael D|Young, Bruce W|Jass, Jeremy R|Rosty, Christophe|Gattas, Michael|Pelzer, Elise|Hopper, John
PMID: 21165777
Journal: Cancer. 2011 Sep 15;117(18):4175-83.
Title: Genetic variation in the transforming growth factor-beta signaling pathway and survival after diagnosis with colon and rectal cancer.
Author: Slattery, Martha L|Lundgreen, Abbie|Herrick, Jennifer S|Wolff, Roger K|Caan, Bette J
PMID: 21365634
Journal: Int J Cancer. 2012 Feb 1;130(3):653-64.
Title: Genetic variation in bone morphogenetic protein and colon and rectal cancer.
Author: Slattery, Martha L|Lundgreen, Abbie|Herrick, Jennifer S|Kadlubar, Susan|Caan, Bette J|Potter, John D|Wolff, Roger K
PMID: 21387313
Journal: Gastroenterology. 2014 Jul;147(1):196-208.e13.
Title: Loss of SMAD4 alters BMP signaling to promote colorectal cancer cell metastasis via activation of Rho and ROCK.
Author: Voorneveld, Philip W|Kodach, Liudmila L|Jacobs, Rutger J|Liv, Nalan|Zonnevylle, A Christiaan|Hoogenboom, Jacob P|Biemond, Izak|Verspaget, Hein W|Hommes, Daniel W|de Rooij, Karien|van Noesel, Carel J M|Morreau, Hans|van Wezel, Tom|Offerhaus, G Johan A|van
PMID: 24704720
Journal: J Natl Cancer Inst. 2015 Jun 13;107(9). pii: djv160.
Title: A Candidate-Pathway Approach to Identify Gene-Environment Interactions: Analyses of Colon Cancer Risk and Survival.
Author: Sharafeldin, Noha|Slattery, Martha L|Liu, Qi|Franco-Villalobos, Conrado|Caan, Bette J|Potter, John D|Yasui, Yutaka
PMID: 26072521
Journal: Br J Cancer. 2015 Aug 11;113(4):686-92.
Title: Target gene mutational pattern in Lynch syndrome colorectal carcinomas according to tumour location and germline mutation.
Author: Pinheiro, Manuela|Pinto, Carla|Peixoto, Ana|Veiga, Isabel|Lopes, Paula|Henrique, Rui|Baldaia, Helena|Carneiro, Fatima|Seruca, Raquel|Tomlinson, Ian|Kovac, Michal|Heinimann, Karl|Teixeira, Manuel R
PMID: 26247575
Journal: Oncotarget. 2017 Mar 7;8(10):16765-16783.
Title: Genetic variants in the TGFbeta-signaling pathway influence expression of miRNAs in colon and rectal normal mucosa and tumor tissue.
Author: Slattery, Martha L|Trivellas, Andromahi|Pellatt, Andrew J|Mullany, Lila E|Stevens, John R|Wolff, Roger K|Herrick, Jennifer S
PMID: 28061442
Journal: Gastroenterology. 2017 Aug;153(2):470-479.e4.
Title: Statin Use After Diagnosis of Colon Cancer and Patient Survival.
Author: Voorneveld, Philip W|Reimers, Marlies S|Bastiaannet, Esther|Jacobs, Rutger J|van Eijk, Ronald|Zanders, Marjolein M J|Herings, Ron M C|van Herk-Sukel, Myrthe P P|Kodach, Liudmila L|van Wezel, Tom|Kuppen, Peter J K|Morreau, Hans|van de Velde, Cornelis J H|H
PMID: 28512021