Primary Site >> Colorectal Cancer

Gene >> BMPR1A

Journal:
Title: Juvenile Polyposis Syndrome
Author: Larsen Haidle, Joy|Howe, James R
PMID: 20301642
Journal: Am J Hum Genet. 2001 Oct;69(4):704-11.
Title: Germline mutations in BMPR1A/ALK3 cause a subset of cases of juvenile polyposis syndrome and of Cowden and Bannayan-Riley-Ruvalcaba syndromes.
Author: Zhou, X P|Woodford-Richens, K|Lehtonen, R|Kurose, K|Aldred, M|Hampel, H|Launonen, V|Virta, S|Pilarski, R|Salovaara, R|Bodmer, W F|Conrad, B A|Dunlop, M|Hodgson, S V|Iwama, T|Jarvinen, H|Kellokumpu, I|Kim, J C|Leggett, B|Markie, D|Mecklin, J P|Neale, K|Phi
PMID: 11536076
Journal: Ann Surg Oncol. 2002 Nov;9(9):901-6.
Title: Germline SMAD4 or BMPR1A mutations and phenotype of juvenile polyposis.
Author: Sayed, M G|Ahmed, A F|Ringold, J R|Anderson, M E|Bair, J L|Mitros, F A|Lynch, H T|Tinley, S T|Petersen, G M|Giardiello, F M|Vogelstein, B|Howe, J R
PMID: 12417513
Journal: Am J Med Genet A. 2003 Nov 1;122A(4):303-14.
Title: Molecular dimensions of gastrointestinal tumors: some thoughts for digestion.
Author: Cohen, M Michael Jr
PMID: 14518068
Journal: Br J Cancer. 2004 Mar 22;90(6):1230-4.
Title: Loss of heterozygosity on 10q and mutational status of PTEN and BMPR1A in colorectal primary tumours and metastases.
Author: Karoui, M|Tresallet, C|Julie, C|Zimmermann, U|Staroz, F|Brams, A|Muti, C|Boulard, C|Robreau, A-M|Puy, H|Malafosse, R|Penna, C|Pruvot, F-R|Thiery, J P|Boileau, C|Rougier, P|Nordlinger, B|Radvanyi, F|Franc, B|Hofmann-Radvanyi, H
PMID: 15026806
Journal: Korean J Gastroenterol. 2005 Feb;45(2):78-87.
Title: [Hereditary colorectal cancer].
Author: Park, Jae-Gahb|Kim, Il-Jin
PMID: 15725711
Journal: Clin Exp Metastasis. 2005;22(5):421-8.
Title: Genetic and pathologic changes associated with lymphovascular invasion of colorectal adenocarcinoma.
Author: Kim, Jin C|Roh, Seon A|Lee, Kang H|Namgung, Hwan|Kim, Jung R|Kim, Jung S
PMID: 16283485
Journal: J Med Genet. 2006 Mar;43(3):e13.
Title: Mapping of hereditary mixed polyposis syndrome (HMPS) to chromosome 10q23 by genomewide high-density single nucleotide polymorphism (SNP) scan and identification of BMPR1A loss of function.
Author: Cao, X|Eu, K W|Kumarasinghe, M P|Li, H H|Loi, C|Cheah, P Y
PMID: 16525031
Journal: Am J Physiol Gastrointest Liver Physiol. 2006 Jul;291(1):G135-45.
Title: Bone morphogenetic protein signaling and growth suppression in colon cancer.
Author: Beck, Stayce E|Jung, Barbara H|Fiorino, Antonio|Gomez, Jessica|Rosario, Eunice Del|Cabrera, Betty L|Huang, Sherry C|Chow, Jimmy Y C|Carethers, John M
PMID: 16769811
Journal: J Chir (Paris). 2007 Jan-Feb;144(1):13-8.
Title: [Colorectal carcinogenesis. 1. Hereditary predisposition and colorectal cancer].
Author: Karoui, M|Tresallet, C|Brouquet, A|Radvanyi, H|Penna, C
PMID: 17369756
Journal: Keio J Med. 2007 Mar;56(1):14-20.
Title: Genetic testing in colorectal cancer: who, when, how and why.
Author: Davidson, Nicholas O
PMID: 17392593
Journal: Br J Cancer. 2007 Nov 5;97(9):1305-9.
Title: National study of colorectal cancer genetics.
Author: Penegar, S|Wood, W|Lubbe, S|Chandler, I|Broderick, P|Papaemmanuil, E|Sellick, G|Gray, R|Peto, J|Houlston, R
PMID: 17895893
Journal: Cancer. 2008 Jan 15;112(2):300-6.
Title: The bone morphogenetic protein pathway is active in human colon adenomas and inactivated in colorectal cancer.
Author: Kodach, Liudmila L|Bleuming, Sylvia A|Musler, Alex R|Peppelenbosch, Maikel P|Hommes, Daniel W|van den Brink, Gijs R|van Noesel, Carel J M|Offerhaus, G Johan A|Hardwick, James C H
PMID: 18008360
Journal: Clin Genet. 2008 Aug;74(2):145-54.
Title: Variable phenotypes associated with 10q23 microdeletions involving the PTEN and BMPR1A genes.
Author: Menko, F H|Kneepkens, C M F|de Leeuw, N|Peeters, E A J|Van Maldergem, L|Kamsteeg, E J|Davidson, R|Rozendaal, L|Lasham, C A|Peeters-Scholte, C M P|Jansweijer, M C|Hilhorst-Hofstee, Y|Gille, J J P|Heins, Y M|Nieuwint, A W M|Sistermans, E A
PMID: 18510548
Journal: Cancer Sci. 2008 Jul;99(7):1348-54.
Title: Individual tumorigenesis pathways of sporadic colorectal adenocarcinomas are associated with the biological behavior of tumors.
Author: Kim, Jin C|Cho, Young K|Roh, Seon A|Yu, Chang S|Gong, Gyungyub|Jang, Se J|Kim, Seon Y|Kim, Yong S
PMID: 18422752
Journal: Cancer Genet Cytogenet. 2008 Feb;181(1):52-4.
Title: A family with two consecutive nonsense mutations in BMPR1A causing juvenile polyposis.
Author: Howe, James R|Chinnathambi, Sathivel|Calva, Daniel|Bair, Jennifer|Pechman, Brenda|Salamon, Agnes|Tam, Beatrix|Simon, Laszlo
PMID: 18262054
Journal: Am J Gastroenterol. 2009 Dec;104(12):3027-33.
Title: Germline bone morphogenesis protein receptor 1A mutation causes colorectal tumorigenesis in hereditary mixed polyposis syndrome.
Author: Cheah, Peh Yean|Wong, Yu Hui|Chau, Yuk Ping|Loi, Carol|Lim, Kiat Hon|Lim, Jit Fong|Koh, Poh Koon|Eu, Kong Weng
PMID: 19773747
Journal: Colorectal Dis. 2010 Jun;12(6):570-3.
Title: Hereditary mixed polyposis syndrome due to a BMPR1A mutation.
Author: O'Riordan, J M|O'Donoghue, D|Green, A|Keegan, D|Hawkes, L A|Payne, S J|Sheahan, K|Winter, D C
PMID: 19438883
Journal: Clin Genet. 2010 Aug;78(2):162-8.
Title: Clinical and molecular characterization of individuals with recurrent genomic disorder at 10q22.3q23.2.
Author: Alliman, S|Coppinger, J|Marcadier, J|Thiese, H|Brock, P|Shafer, S|Weaver, C|Asamoah, A|Leppig, K|Dyack, S|Morash, B|Schultz, R|Torchia, B S|Lamb, A N|Bejjani, B A
PMID: 20345475
Journal: Cancer Treat Res. 2010;155:85-103.
Title: Tgf-beta signaling alterations and colon cancer.
Author: Bellam, Naresh|Pasche, Boris
PMID: 20517689
Journal: PLoS One. 2010 Dec 22;5(12):e15661.
Title: Somatic mutation profiles of MSI and MSS colorectal cancer identified by whole exome next generation sequencing and bioinformatics analysis.
Author: Timmermann, Bernd|Kerick, Martin|Roehr, Christina|Fischer, Axel|Isau, Melanie|Boerno, Stefan T|Wunderlich, Andrea|Barmeyer, Christian|Seemann, Petra|Koenig, Jana|Lappe, Michael|Kuss, Andreas W|Garshasbi, Masoud|Bertram, Lars|Trappe, Kathrin|Werber, Martin
PMID: 21203531
Journal: World J Gastroenterol. 2011 Nov 28;17(44):4839-44.
Title: Juvenile polyposis syndrome.
Author: Brosens, Lodewijk Aa|Langeveld, Danielle|van Hattem, W Arnout|Giardiello, Francis M|Offerhaus, G Johan A
PMID: 22171123
Journal: Cancer. 2011 Sep 15;117(18):4175-83.
Title: Genetic variation in the transforming growth factor-beta signaling pathway and survival after diagnosis with colon and rectal cancer.
Author: Slattery, Martha L|Lundgreen, Abbie|Herrick, Jennifer S|Wolff, Roger K|Caan, Bette J
PMID: 21365634
Journal: Int J Cancer. 2012 Feb 1;130(3):653-64.
Title: Genetic variation in bone morphogenetic protein and colon and rectal cancer.
Author: Slattery, Martha L|Lundgreen, Abbie|Herrick, Jennifer S|Kadlubar, Susan|Caan, Bette J|Potter, John D|Wolff, Roger K
PMID: 21387313
Journal: Clin Genet. 2012 Feb;81(2):110-6.
Title: Juvenile polyposis and other intestinal polyposis syndromes with microdeletions of chromosome 10q22-23.
Author: Dahdaleh, F S|Carr, J C|Calva, D|Howe, J R
PMID: 21834858
Journal: Dis Colon Rectum. 2012 Aug;55(8):886-92.
Title: The prevalence of hereditary hemorrhagic telangiectasia in juvenile polyposis syndrome.
Author: O'Malley, Margaret|LaGuardia, Lisa|Kalady, Matthew F|Parambil, Joseph|Heald, Brandie|Eng, Charis|Church, James|Burke, Carol A
PMID: 22810475
Journal: Dis Colon Rectum. 2012 Oct;55(10):1038-43.
Title: Juvenile polyposis syndrome: a study of genotype, phenotype, and long-term outcome.
Author: Latchford, Andrew R|Neale, Kay|Phillips, Robin K S|Clark, Susan K
PMID: 22965402
Journal: J Gastrointest Oncol. 2012 Dec;3(4):362-8.
Title: The real face of juvenile polyposis syndrome.
Author: Tam, Beatrix|Salamon, Agnes|Bajtai, Attila|Nemeth, Annamaria|Kiss, Janos|Simon, Laszlo|Molnar, Tamas
PMID: 23205314
Journal: Scand J Gastroenterol. 2013 Jun;48(6):672-8.
Title: Exome sequencing in diagnostic evaluation of colorectal cancer predisposition in young patients.
Author: Tanskanen, Tomas|Gylfe, Alexandra E|Katainen, Riku|Taipale, Minna|Renkonen-Sinisalo, Laura|Mecklin, Jukka-Pekka|Jarvinen, Heikki|Tuupanen, Sari|Kilpivaara, Outi|Vahteristo, Pia|Aaltonen, Lauri A
PMID: 23544471
Journal: Gut Liver. 2013 Nov;7(6):747-51.
Title: A novel germline mutation in exon 10 of the SMAD4 gene in a familial juvenile polyposis.
Author: Jee, Myung Jin|Yoon, Soon Man|Kim, Eui Joong|Choi, Hyun-Jung|Kim, Jong-Won|Sung, Ro Hyun|Han, Joung Ho|Chae, Hee Bok|Park, Seon Mee|Youn, Sei Jin
PMID: 24312718
Journal: Gastroenterology. 2014 Jul;147(1):196-208.e13.
Title: Loss of SMAD4 alters BMP signaling to promote colorectal cancer cell metastasis via activation of Rho and ROCK.
Author: Voorneveld, Philip W|Kodach, Liudmila L|Jacobs, Rutger J|Liv, Nalan|Zonnevylle, A Christiaan|Hoogenboom, Jacob P|Biemond, Izak|Verspaget, Hein W|Hommes, Daniel W|de Rooij, Karien|van Noesel, Carel J M|Morreau, Hans|van Wezel, Tom|Offerhaus, G Johan A|van
PMID: 24704720
Journal: Jpn J Clin Oncol. 2014 Oct;44(10):1004-8.
Title: Identification of coding exon 3 duplication in the BMPR1A gene in a patient with juvenile polyposis syndrome.
Author: Yamaguchi, Junya|Nagayama, Satoshi|Chino, Akiko|Sakata, Ai|Yamamoto, Noriko|Sato, Yuri|Ashihara, Yuumi|Kita, Mizuho|Nomura, Sachio|Ishikawa, Yuichi|Igarashi, Masahiro|Ueno, Masashi|Arai, Masami
PMID: 25129392
Journal: J Clin Oncol. 2015 Feb 10;33(5):426-32.
Title: Genetic diagnosis of high-penetrance susceptibility for colorectal cancer (CRC) is achievable for a high proportion of familial CRC by exome sequencing.
Author: Chubb, Daniel|Broderick, Peter|Frampton, Matthew|Kinnersley, Ben|Sherborne, Amy|Penegar, Steven|Lloyd, Amy|Ma, Yussanne P|Dobbins, Sara E|Houlston, Richard S
PMID: 25559809
Journal: Ann Clin Biochem. 2015 Nov;52(Pt 6):690-2.
Title: The Mendelian colorectal cancer syndromes.
Author: Tomlinson, Ian
PMID: 26169059
Journal: Oncogene. 2015 Apr 9;34(15):1968-78.
Title: MicroRNA-885-3p inhibits the growth of HT-29 colon cancer cell xenografts by disrupting angiogenesis via targeting BMPR1A and blocking BMP/Smad/Id1 signaling.
Author: Xiao, F|Qiu, H|Cui, H|Ni, X|Li, J|Liao, W|Lu, L|Ding, K
PMID: 24882581
Journal: Fam Cancer. 2016 Oct;15(4):553-62.
Title: Rapid detection of germline mutations for hereditary gastrointestinal polyposis/cancers using HaloPlex target enrichment and high-throughput sequencing technologies.
Author: Kohda, Masakazu|Kumamoto, Kensuke|Eguchi, Hidetaka|Hirata, Tomoko|Tada, Yuhki|Tanakaya, Kohji|Akagi, Kiwamu|Takenoshita, Seiichi|Iwama, Takeo|Ishida, Hideyuki|Okazaki, Yasushi
PMID: 26837502
Journal: World J Gastroenterol. 2016 Feb 21;22(7):2314-25.
Title: Mutation analysis of 13 driver genes of colorectal cancer-related pathways in Taiwanese patients.
Author: Chang, Yuli Christine|Chang, Jan-Gowth|Liu, Ta-Chih|Lin, Chien-Yu|Yang, Shu-Fen|Ho, Cheng-Mao|Chen, William Tzu-Liang|Chang, Ya-Sian
PMID: 26900293
Journal: Oncotarget. 2016 Nov 8;7(45):72908-72922.
Title: Genomic characterization of liver metastases from colorectal cancer patients.
Author: Sayagues, Jose Maria|Corchete, Luis Antonio|Gutierrez, Maria Laura|Sarasquete, Maria Eugenia|Del Mar Abad, Maria|Bengoechea, Oscar|Ferminan, Encarna|Anduaga, Maria Fernanda|Del Carmen, Sofia|Iglesias, Manuel|Esteban, Carmen|Angoso, Maria|Alcazar, Jose Ant
PMID: 27662660
Journal: Fam Cancer. 2017 Apr;16(2):195-203.
Title: Expanding the genotype-phenotype spectrum in hereditary colorectal cancer by gene panel testing.
Author: Rohlin, Anna|Rambech, Eva|Kvist, Anders|Torngren, Therese|Eiengard, Frida|Lundstam, Ulf|Zagoras, Theofanis|Gebre-Medhin, Samuel|Borg, Ake|Bjork, Jan|Nilbert, Mef|Nordling, Margareta
PMID: 27696107
Journal: Gastroenterology. 2017 Aug;153(2):470-479.e4.
Title: Statin Use After Diagnosis of Colon Cancer and Patient Survival.
Author: Voorneveld, Philip W|Reimers, Marlies S|Bastiaannet, Esther|Jacobs, Rutger J|van Eijk, Ronald|Zanders, Marjolein M J|Herings, Ron M C|van Herk-Sukel, Myrthe P P|Kodach, Liudmila L|van Wezel, Tom|Kuppen, Peter J K|Morreau, Hans|van de Velde, Cornelis J H|H
PMID: 28512021
Journal: Curr Genomics. 2017 Aug;18(4):341-359.
Title: Familial Colorectal Cancer Type X.
Author: Zetner, Diana Bregner|Bisgaard, Marie Luise
PMID: 29081690
Journal: Curr Probl Cancer. 2017 Nov - Dec;41(6):388-397.
Title: Familial Colorectal Cancer Type X (FCCTX) and the correlation with various genes-A systematic review.
Author: Nejadtaghi, Mahdieh|Jafari, Hamideh|Farrokhi, Effat|Samani, Keihan Ghatreh
PMID: 29096939
Journal: Fam Cancer. 2018 Jan;17(1):87-90.
Title: Co-occurrence of Lynch syndrome and juvenile polyposis syndrome confirmed by multigene panel testing.
Author: Silva-Smith, Rachel|Sussman, Daniel A
PMID: 28600700
Journal: Fam Cancer. 2018 Apr;17(2):205-208.
Title: Screening of BMPR1a for pathogenic mutations in familial colorectal cancer type X families from Newfoundland.
Author: Evans, Daniel R|Green, Jane S|Woods, Michael O
PMID: 28660566
Journal: Eur J Hum Genet. 2018 Jul 2. pii: 10.1038/s41431-018-0207-2.
Title: Optimization of the diagnosis of inherited colorectal cancer using NGS and capture of exonic and intronic sequences of panel genes.
Author: Baert-Desurmont, Stephanie|Coutant, Sophie|Charbonnier, Francoise|Macquere, Pierre|Lecoquierre, Francois|Schwartz, Mathias|Blanluet, Maud|Vezain, Myriam|Lanos, Raphael|Quenez, Olivier|Bou, Jacqueline|Bouvignies, Emilie|Fourneaux, Steeve|Manase, Sandrine|V
PMID: 29967336