Primary Site >> Colorectal Cancer
Gene >> BMPR1A
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Ref: Juvenile Polyposis Syndrome PMID: 20301642 |
Ref: Germline mutations in BMPR1A/ALK3 cause a subset of cases of juvenile polyposis syndrome and of Cowden and Bannayan-Riley-Ruvalcaba syndromes. PMID: 11536076 |
Ref: Germline SMAD4 or BMPR1A mutations and phenotype of juvenile polyposis. PMID: 12417513 |
Ref: Molecular dimensions of gastrointestinal tumors: some thoughts for digestion. PMID: 14518068 |
Ref: Loss of heterozygosity on 10q and mutational status of PTEN and BMPR1A in colorectal primary tumours and metastases. PMID: 15026806 |
Ref: [Hereditary colorectal cancer]. PMID: 15725711 Ref: Genetic and pathologic changes associated with lymphovascular invasion of colorectal adenocarcinoma. PMID: 16283485 |
Ref: Mapping of hereditary mixed polyposis syndrome (HMPS) to chromosome 10q23 by genomewide high-density single nucleotide polymorphism (SNP) scan and identification of BMPR1A loss of function. PMID: 16525031 Ref: Bone morphogenetic protein signaling and growth suppression in colon cancer. PMID: 16769811 |
Ref: [Colorectal carcinogenesis. 1. Hereditary predisposition and colorectal cancer]. PMID: 17369756 Ref: Genetic testing in colorectal cancer: who, when, how and why. PMID: 17392593 Ref: National study of colorectal cancer genetics. PMID: 17895893 |
Ref: The bone morphogenetic protein pathway is active in human colon adenomas and inactivated in colorectal cancer. PMID: 18008360 Ref: A family with two consecutive nonsense mutations in BMPR1A causing juvenile polyposis. PMID: 18262054 Ref: Individual tumorigenesis pathways of sporadic colorectal adenocarcinomas are associated with the biological behavior of tumors. PMID: 18422752 Ref: Variable phenotypes associated with 10q23 microdeletions involving the PTEN and BMPR1A genes. PMID: 18510548 |
Ref: Germline bone morphogenesis protein receptor 1A mutation causes colorectal tumorigenesis in hereditary mixed polyposis syndrome. PMID: 19773747 |
Ref: Hereditary mixed polyposis syndrome due to a BMPR1A mutation. PMID: 19438883 Ref: Clinical and molecular characterization of individuals with recurrent genomic disorder at 10q22.3q23.2. PMID: 20345475 Ref: Tgf-beta signaling alterations and colon cancer. PMID: 20517689 Ref: Somatic mutation profiles of MSI and MSS colorectal cancer identified by whole exome next generation sequencing and bioinformatics analysis. PMID: 21203531 |
Ref: Genetic variation in the transforming growth factor-beta signaling pathway and survival after diagnosis with colon and rectal cancer. PMID: 21365634 Ref: Juvenile polyposis syndrome. PMID: 22171123 |
Ref: Genetic variation in bone morphogenetic protein and colon and rectal cancer. PMID: 21387313 Ref: Juvenile polyposis and other intestinal polyposis syndromes with microdeletions of chromosome 10q22-23. PMID: 21834858 Ref: The prevalence of hereditary hemorrhagic telangiectasia in juvenile polyposis syndrome. PMID: 22810475 Ref: Juvenile polyposis syndrome: a study of genotype, phenotype, and long-term outcome. PMID: 22965402 Ref: The real face of juvenile polyposis syndrome. PMID: 23205314 |
Ref: Exome sequencing in diagnostic evaluation of colorectal cancer predisposition in young patients. PMID: 23544471 Ref: A novel germline mutation in exon 10 of the SMAD4 gene in a familial juvenile polyposis. PMID: 24312718 |
Ref: Loss of SMAD4 alters BMP signaling to promote colorectal cancer cell metastasis via activation of Rho and ROCK. PMID: 24704720 Ref: Identification of coding exon 3 duplication in the BMPR1A gene in a patient with juvenile polyposis syndrome. PMID: 25129392 |
Ref: MicroRNA-885-3p inhibits the growth of HT-29 colon cancer cell xenografts by disrupting angiogenesis via targeting BMPR1A and blocking BMP/Smad/Id1 signaling. PMID: 24882581 Ref: Genetic diagnosis of high-penetrance susceptibility for colorectal cancer (CRC) is achievable for a high proportion of familial CRC by exome sequencing. PMID: 25559809 Ref: The Mendelian colorectal cancer syndromes. PMID: 26169059 |
Ref: Rapid detection of germline mutations for hereditary gastrointestinal polyposis/cancers using HaloPlex target enrichment and high-throughput sequencing technologies. PMID: 26837502 Ref: Mutation analysis of 13 driver genes of colorectal cancer-related pathways in Taiwanese patients. PMID: 26900293 Ref: Genomic characterization of liver metastases from colorectal cancer patients. PMID: 27662660 |
Ref: Expanding the genotype-phenotype spectrum in hereditary colorectal cancer by gene panel testing. PMID: 27696107 Ref: Statin Use After Diagnosis of Colon Cancer and Patient Survival. PMID: 28512021 Ref: Familial Colorectal Cancer Type X. PMID: 29081690 Ref: Familial Colorectal Cancer Type X (FCCTX) and the correlation with various genes-A systematic review. PMID: 29096939 |
Ref: Co-occurrence of Lynch syndrome and juvenile polyposis syndrome confirmed by multigene panel testing. PMID: 28600700 Ref: Screening of BMPR1a for pathogenic mutations in familial colorectal cancer type X families from Newfoundland. PMID: 28660566 Ref: Optimization of the diagnosis of inherited colorectal cancer using NGS and capture of exonic and intronic sequences of panel genes. PMID: 29967336 |