Literatures

Primary Site >> Colorectal Cancer

Gene >> BMP4

1.
Journal:	Cancer Res. 2002 May 15;62(10):2744-8.
Title:	Oncogenic beta-catenin is required for bone morphogenetic protein 4 expression in human cancer cells.
Author:	Kim, Jung-Sik\|Crooks, Heather\|Dracheva, Tatiana\|Nishanian, Tagvor G\|Singh, Baljit\|Jen, Jin\|Waldman, Todd
PMID:	12019147

2.
Journal:	Cancer Biol Ther. 2004 Jul;3(7):667-75. Epub 2004 Jul 10.
Title:	Suppression of tumorigenesis and activation of Wnt signaling by bone morphogenetic protein 4 in human cancer cells.
Author:	Nishanian, Tagvor G\|Kim, Jung-Sik\|Foxworth, Aaron\|Waldman, Todd
PMID:	15197354

3.
Journal:	J Cell Biol. 2004 Oct 11;167(1):123-33. Epub 2004 Oct 4.
Title:	Disruption of LTBP-4 function reduces TGF-beta activation and enhances BMP-4 signaling in the lung.
Author:	Koli, Katri\|Wempe, Frank\|Sterner-Kock, Anja\|Kantola, Anna\|Komor, Martina\|Hofmann, Wolf-K\|von Melchner, Harald\|Keski-Oja, Jorma
PMID:	15466481

4.
Journal:	Int J Oncol. 2004 Oct;25(4):1049-56.
Title:	Search for epithelial-specific mRNAs in peripheral blood of patients with colon cancer by RT-PCR.
Author:	Solmi, Rossella\|De Sanctis, Paola\|Zucchini, Cinzia\|Ugolini, Giampaolo\|Rosati, Giancarlo\|Del Governatore, Marco\|Coppola, Domenico\|Yeatman, Thymothy J\|Lenzi, Luca\|Caira, Antonello\|Zanotti, Simone\|Taffurelli, Mario\|Carinci, Paolo\|Valvassori, Luisa\|Strippoli,
PMID:	15375555

5.
Journal:	Br J Cancer. 2005 Apr 11;92(7):1193-200.
Title:	Gene expression profiling of colorectal adenomas and early invasive carcinomas by cDNA array analysis.
Author:	Nosho, K\|Yamamoto, H\|Adachi, Y\|Endo, T\|Hinoda, Y\|Imai, K
PMID:	15785755

6.
Journal:	Development. 2006 Mar;133(5):833-43.
Title:	Foxf1 and Foxf2 control murine gut development by limiting mesenchymal Wnt signaling and promoting extracellular matrix production.
Author:	Ormestad, Mattias\|Astorga, Jeanette\|Landgren, Henrik\|Wang, Tao\|Johansson, Bengt R\|Miura, Naoyuki\|Carlsson, Peter
PMID:	16439479

7.
Journal:	Mol Cell Proteomics. 2006 Aug;5(8):1471-83.
Title:	Proteomics-based validation of genomic data: applications in colorectal cancer diagnosis.
Author:	Madoz-Gurpide, Juan\|Lopez-Serra, Paula\|Martinez-Torrecuadrada, Jorge Luis\|Sanchez, Lydia\|Lombardia, Luis\|Casal, J Ignacio
PMID:	16733264

8.
Journal:	Int J Mol Med. 2006 Dec;18(6):1019-23.
Title:	Hedgehog signaling pathway and gastrointestinal stem cell signaling network (review).
Author:	Katoh, Yuriko\|Katoh, Masaru
PMID:	17089004

9.
Journal:	Exp Cell Res. 2007 Mar 10;313(5):1033-44.
Title:	Bone morphogenetic protein-4 is overexpressed in colonic adenocarcinomas and promotes migration and invasion of HCT116 cells.
Author:	Deng, Haiyun\|Makizumi, Ryouji\|Ravikumar, T S\|Dong, Huali\|Yang, Wancai\|Yang, Weng-Lang
PMID:	17275810

10.
Journal:	Stem Cells. 2007 Jun;25(6):1498-506. Epub 2007 Feb 22.
Title:	Gene expression analysis of hematopoietic progenitor cells identifies Dlg7 as a potential stem cell gene.
Author:	Gudmundsson, Kristbjorn Orri\|Thorsteinsson, Leifur\|Sigurjonsson, Olafur E\|Keller, Jonathan R\|Olafsson, Karl\|Egeland, Torstein\|Gudmundsson, Sveinn\|Rafnar, Thorunn
PMID:	17322106

11.
Journal:	Cancer Lett. 2007 Oct 28;256(2):207-17. Epub 2007 Jul 20.
Title:	Bone morphogenetic protein-4 inhibits heat-induced apoptosis by modulating MAPK pathways in human colon cancer HCT116 cells.
Author:	Deng, Haiyun\|Ravikumar, T S\|Yang, Weng-Lang
PMID:	17640799

12.
Journal:	J Cell Physiol. 2008 Apr;215(1):192-203.
Title:	Regulation of human Cripto-1 gene expression by TGF-beta1 and BMP-4 in embryonal and colon cancer cells.
Author:	Mancino, Mario\|Strizzi, Luigi\|Wechselberger, Christian\|Watanabe, Kazuhide\|Gonzales, Monica\|Hamada, Shin\|Normanno, Nicola\|Salomon, David S\|Bianco, Caterina
PMID:	17941089

13.
Journal:	Nat Genet. 2008 Dec;40(12):1426-35.
Title:	Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer.
Author:	Houlston, Richard S\|Webb, Emily\|Broderick, Peter\|Pittman, Alan M\|Di Bernardo, Maria Chiara\|Lubbe, Steven\|Chandler, Ian\|Vijayakrishnan, Jayaram\|Sullivan, Kate\|Penegar, Steven\|Carvajal-Carmona, Luis\|Howarth, Kimberley\|Jaeger, Emma\|Spain, Sarah L\|Walther, Ax
PMID:	19011631

14.
Journal:	Biochem Pharmacol. 2009 Jan 15;77(2):186-95.
Title:	Suppression of beta-catenin signaling by liver X receptor ligands.
Author:	Uno, Shigeyuki\|Endo, Kaori\|Jeong, Yangsik\|Kawana, Katsuyoshi\|Miyachi, Hiroyuki\|Hashimoto, Yuichi\|Makishima, Makoto
PMID:	18983830

15.
Journal:	Cancer Lett. 2009 Aug 28;281(2):220-31.
Title:	Overexpression of bone morphogenetic protein 4 enhances the invasiveness of Smad4-deficient human colorectal cancer cells.
Author:	Deng, Haiyun\|Ravikumar, T S\|Yang, Weng-Lang
PMID:	19321257

16.
Journal:	Hum Mutat. 2011 Jan;32(1):E1928-38.
Title:	Evaluation of germline BMP4 mutation as a cause of colorectal cancer.
Author:	Lubbe, Steven J\|Pittman, Alan M\|Matijssen, Cornelis\|Twiss, Philip\|Olver, Bianca\|Lloyd, Amy\|Qureshi, Mobshra\|Brown, Nathan\|Nye, Emma\|Stamp, Gordon\|Blagg, Julian\|Houlston, Richard S
PMID:	20949628

17.
Journal:	Gastroenterology. 2011 Jan;140(1):297-309.
Title:	Bone morphogenetic protein 4 induces differentiation of colorectal cancer stem cells and increases their response to chemotherapy in mice.
Author:	Lombardo, Ylenia\|Scopelliti, Alessandro\|Cammareri, Patrizia\|Todaro, Matilde\|Iovino, Flora\|Ricci-Vitiani, Lucia\|Gulotta, Gaspare\|Dieli, Francesco\|de Maria, Ruggero\|Stassi, Giorgio
PMID:	20951698

18.
Journal:	Cancer. 2011 Sep 15;117(18):4175-83.
Title:	Genetic variation in the transforming growth factor-beta signaling pathway and survival after diagnosis with colon and rectal cancer.
Author:	Slattery, Martha L\|Lundgreen, Abbie\|Herrick, Jennifer S\|Wolff, Roger K\|Caan, Bette J
PMID:	21365634

19.
Journal:	PLoS Genet. 2011 Jun;7(6):e1002105.
Title:	Multiple common susceptibility variants near BMP pathway loci GREM1, BMP4, and BMP2 explain part of the missing heritability of colorectal cancer.
Author:	Tomlinson, Ian P M\|Carvajal-Carmona, Luis G\|Dobbins, Sara E\|Tenesa, Albert\|Jones, Angela M\|Howarth, Kimberley\|Palles, Claire\|Broderick, Peter\|Jaeger, Emma E M\|Farrington, Susan\|Lewis, Annabelle\|Prendergast, James G D\|Pittman, Alan M\|Theodoratou, Evropi\|Ol
PMID:	21655089

20.
Journal:	Cancers (Basel). 2011 Apr 11;3(2):1929-46.
Title:	Colorectal cancer stem cells and cell death.
Author:	Catalano, Veronica\|Gaggianesi, Miriam\|Spina, Valentina\|Iovino, Flora\|Dieli, Francesco\|Stassi, Giorgio\|Todaro, Matilde
PMID:	24212789

21.
Journal:	PLoS One. 2012;7(9):e45332.
Title:	Hedgehog pathway signaling regulates human colon carcinoma HT-29 epithelial cell line apoptosis and cytokine secretion.
Author:	Yoshimoto, Agnes N\|Bernardazzi, Claudio\|Carneiro, Antonio Jose V\|Elia, Celeste C S\|Martinusso, Cesonia A\|Ventura, Grasiella M\|Castelo-Branco, Morgana T L\|de Souza, Heitor S P
PMID:	23028941

22.
Journal:	PLoS One. 2012;7(8):e42407.
Title:	Association of Caucasian-identified variants with colorectal cancer risk in Singapore Chinese.
Author:	Thean, Lai Fun\|Li, Hui Hua\|Teo, Yik Ying\|Koh, Woon-Puay\|Yuan, Jian-Min\|Teoh, Mei Lin\|Koh, Poh Koon\|Tang, Choong Leong\|Cheah, Peh Yean
PMID:	22879968

23.
Journal:	Cancer Genet. 2012 Jun;205(6):267-77.
Title:	Bone morphogenetic protein 4-a fascinating regulator of cancer cell behavior.
Author:	Kallioniemi, Anne
PMID:	22749032

24.
Journal:	Am J Physiol Gastrointest Liver Physiol. 2012 May 15;302(10):G1223-30.
Title:	Oncogenic KRAS regulates BMP4 expression in colon cancer cell lines.
Author:	Duerr, Eva-Maria\|Mizukami, Yusuke\|Moriichi, Kentaro\|Gala, Manish\|Jo, Won-Seok\|Kikuchi, Hirotoshi\|Xavier, Ramnik J\|Chung, Daniel C
PMID:	22383492

25.
Journal:	Mol Biol Rep. 2012 May;39(5):5239-51.
Title:	Bone morphogenetic protein-4 polymorphism and colorectal cancer risk: a meta analysis.
Author:	Li, Jin\|Sun, Chuang\|Yuan, Yuerong\|Liu, Li\|Xiong, Guanglian\|Wu, Jing
PMID:	22170598

26.
Journal:	Oncogene. 2012 Aug 16;31(33):3777-84.
Title:	The 14q22.2 colorectal cancer variant rs4444235 shows cis-acting regulation of BMP4.
Author:	Lubbe, S J\|Pittman, A M\|Olver, B\|Lloyd, A\|Vijayakrishnan, J\|Naranjo, S\|Dobbins, S\|Broderick, P\|Gomez-Skarmeta, J L\|Houlston, R S
PMID:	22158048

27.
Journal:	Int J Cancer. 2012 Feb 1;130(3):653-64.
Title:	Genetic variation in bone morphogenetic protein and colon and rectal cancer.
Author:	Slattery, Martha L\|Lundgreen, Abbie\|Herrick, Jennifer S\|Kadlubar, Susan\|Caan, Bette J\|Potter, John D\|Wolff, Roger K
PMID:	21387313

28.
Journal:	Cancer Res. 2012 Apr 15;72(8):2036-44.
Title:	Characterization of gene-environment interactions for colorectal cancer susceptibility loci.
Author:	Hutter, Carolyn M\|Chang-Claude, Jenny\|Slattery, Martha L\|Pflugeisen, Bethann M\|Lin, Yi\|Duggan, David\|Nan, Hongmei\|Lemire, Mathieu\|Rangrej, Jagadish\|Figueiredo, Jane C\|Jiao, Shuo\|Harrison, Tabitha A\|Liu, Yan\|Chen, Lin S\|Stelling, Deanna L\|Warnick, Greg S\|H
PMID:	22367214

29.
Journal:	Carcinogenesis. 2013 Feb;34(2):314-8.
Title:	BMP2/BMP4 colorectal cancer susceptibility loci in northern and southern European populations.
Author:	Fernandez-Rozadilla, Ceres\|Palles, Claire\|Carvajal-Carmona, Luis\|Peterlongo, Paolo\|Nici, Carmela\|Veneroni, Silvia\|Pinheiro, Manuela\|Teixeira, Manuel R\|Moreno, Victor\|Lamas, Maria-Jesus\|Baiget, Montserrat\|Lopez-Fernandez, L A\|Gonzalez, Dolors\|Brea-Fernande
PMID:	23161572

30.
Journal:	Food Chem Toxicol. 2013 May;55:424-33.
Title:	Suppression of Src/ERK and GSK-3/beta-catenin signaling by pinosylvin inhibits the growth of human colorectal cancer cells.
Author:	Park, Eun-Jung\|Chung, Hwa-Jin\|Park, Hyen Joo\|Kim, Gi Dae\|Ahn, Yong-Hyun\|Lee, Sang Kook
PMID:	23333577

31.
Journal:	PLoS One. 2014 Nov 6;9(11):e111914.
Title:	Multiple functional risk variants in a SMAD7 enhancer implicate a colorectal cancer risk haplotype.
Author:	Fortini, Barbara K\|Tring, Stephanie\|Plummer, Sarah J\|Edlund, Christopher K\|Moreno, Victor\|Bresalier, Robert S\|Barry, Elizabeth L\|Church, Timothy R\|Figueiredo, Jane C\|Casey, Graham
PMID:	25375357

32.
Journal:	PLoS One. 2014 Jun 26;9(6):e100060.
Title:	Single nucleotide polymorphisms associated with colorectal cancer susceptibility and loss of heterozygosity in a Taiwanese population.
Author:	Yang, Chih-Yung\|Lu, Ruey-Hwa\|Lin, Chien-Hsing\|Jen, Chih-Hung\|Tung, Chien-Yi\|Yang, Shung-Haur\|Lin, Jen-Kou\|Jiang, Jeng-Kai\|Lin, Chi-Hung
PMID:	24968322

33.
Journal:	Nat Cell Biol. 2014 Jul;16(7):695-707.
Title:	The transcription factor GATA6 enables self-renewal of colon adenoma stem cells by repressing BMP gene expression.
Author:	Whissell, Gavin\|Montagni, Elisa\|Martinelli, Paola\|Hernando-Momblona, Xavier\|Sevillano, Marta\|Jung, Peter\|Cortina, Carme\|Calon, Alexandre\|Abuli, Anna\|Castells, Antoni\|Castellvi-Bel, Sergi\|Nacht, Ana Silvina\|Sancho, Elena\|Stephan-Otto Attolini, Camille\|Vice
PMID:	24952462

34.
Journal:	PLoS One. 2014 Jun 16;9(6):e100133.
Title:	The common variant rs4444235 near BMP4 confers genetic susceptibility of colorectal cancer: an updated meta-analysis based on a comprehensive statistical strategy.
Author:	Liu, Li\|Su, Qinji\|Li, Lixia\|Lin, Xiaohui\|Gan, Yu\|Chen, Sidong
PMID:	24932582

35.
Journal:	Carcinogenesis. 2014 Sep;35(9):2025-30.
Title:	Shared and independent colorectal cancer risk alleles in TGFbeta-related genes in African and European Americans.
Author:	Kupfer, Sonia S\|Skol, Andrew D\|Hong, Ellie\|Ludvik, Anton\|Kittles, Rick A\|Keku, Temitope O\|Sandler, Robert S\|Ellis, Nathan A
PMID:	24753543

36.
Journal:	Carcinogenesis. 2014 Jan;35(1):96-102.
Title:	Estrogen receptor alpha or beta loss in the colon of Min/+ mice promotes crypt expansion and impairs TGFbeta and HNF3beta signaling.
Author:	Hasson, Rian M\|Briggs, Alexandra\|Carothers, Adelaide M\|Davids, Jennifer S\|Wang, Jiping\|Javid, Sara H\|Cho, Nancy L\|Bertagnolli, Monica M
PMID:	24104551

37.
Journal:	Oncogene. 2014 Jul 17;33(29):3803-11.
Title:	BMP4/Thrombospondin-1 loop paracrinically inhibits tumor angiogenesis and suppresses the growth of solid tumors.
Author:	Tsuchida, R\|Osawa, T\|Wang, F\|Nishii, R\|Das, B\|Tsuchida, S\|Muramatsu, M\|Takahashi, T\|Inoue, T\|Wada, Y\|Minami, T\|Yuasa, Y\|Shibuya, M
PMID:	24013228

38.
Journal:	Cytokine. 2015 Apr;72(2):154-9.
Title:	Common genetic variant on BMP4 contributes to colorectal adenoma and cancer: A meta-analysis based on 15 studies.
Author:	Zhou, Lei\|Xie, Jun\|Gu, Er-li\|Huang, Yao\|Qu, Yan\|Xu, Ai-Ping\|Zhu, Yin\|Wang, Hong
PMID:	25647270

39.
Journal:	Pathol Oncol Res. 2015 Sep;21(4):901-8.
Title:	Differential Expression of Sonic Hedgehog Protein in Human Hepatocellular Carcinoma and Intrahepatic Cholangiocarcinoma.
Author:	Al-Bahrani, Redha\|Nagamori, Seishi\|Leng, Roger\|Petryk, Anna\|Sergi, Consolato
PMID:	25740074

40.
Journal:	Environ Res. 2015 Jul;140:185-90.
Title:	Effects of airborne particulate matter on alternative pre-mRNA splicing in colon cancer cells.
Author:	Buggiano, Valeria\|Petrillo, Ezequiel\|Allo, Mariano\|Lafaille, Celina\|Redal, Maria Ana\|Alghamdi, Mansour A\|Khoder, Mamdouh I\|Shamy, Magdy\|Munoz, Manuel J\|Kornblihtt, Alberto R
PMID:	25863591

41.
Journal:	Oncotarget. 2015 Aug 21;6(24):20540-54.
Title:	Dragon (repulsive guidance molecule b, RGMb) is a novel gene that promotes colorectal cancer growth.
Author:	Shi, Ying\|Chen, Guo-Bin\|Huang, Xiao-Xiao\|Xiao, Chuan-Xing\|Wang, Huan-Huan\|Li, Ye-Sen\|Zhang, Jin-Fang\|Li, Shao\|Xia, Yin\|Ren, Jian-Lin\|Guleng, Bayasi
PMID:	26029998

42.
Journal:	J Natl Cancer Inst. 2015 Jun 13;107(9). pii: djv160.
Title:	A Candidate-Pathway Approach to Identify Gene-Environment Interactions: Analyses of Colon Cancer Risk and Survival.
Author:	Sharafeldin, Noha\|Slattery, Martha L\|Liu, Qi\|Franco-Villalobos, Conrado\|Caan, Bette J\|Potter, John D\|Yasui, Yutaka
PMID:	26072521

43.
Journal:	Mol Cancer Ther. 2015 Nov;14(11):2527-40.
Title:	Effective Inhibition of Bone Morphogenetic Protein Function by Highly Specific Llama-Derived Antibodies.
Author:	Calpe, Silvia\|Wagner, Koen\|El Khattabi, Mohamed\|Rutten, Lucy\|Zimberlin, Cheryl\|Dolk, Edward\|Verrips, C Theo\|Medema, Jan Paul\|Spits, Hergen\|Krishnadath, Kausilia K
PMID:	26351325

44.
Journal:	Pharmacogenomics J. 2016 Apr;16(2):173-9.
Title:	A subset of genetic susceptibility variants for colorectal cancer also has prognostic value.
Author:	Noci, S\|Dugo, M\|Bertola, F\|Melotti, F\|Vannelli, A\|Dragani, T A\|Galvan, A
PMID:	25963333

45.
Journal:	Tumour Biol. 2016 Feb;37(2):2243-55.
Title:	BMP pathway suppression is an early event in inflammation-driven colon neoplasmatogenesis of uPA-deficient mice.
Author:	Karagiannis, George S\|Afaloniati, Hara\|Karamanavi, Elisavet\|Poutahidis, Theofilos\|Angelopoulou, Katerina
PMID:	26358253

46.
Journal:	Cancer Res. 2017 Aug 1;77(15):4026-4038.
Title:	Autocrine BMP-4 Signaling Is a Therapeutic Target in Colorectal Cancer.
Author:	Yokoyama, Yuichiro\|Watanabe, Toshiaki\|Tamura, Yusuke\|Hashizume, Yoshinobu\|Miyazono, Kohei\|Ehata, Shogo
PMID:	28611046

47.
Journal:	Oncol Lett. 2017 Dec;14(6):7653-7668.
Title:	Therapeutic strategies against cancer stem cells in human colorectal cancer.
Author:	Szarynska, Magdalena\|Olejniczak, Agata\|Kobiela, Jaroslaw\|Spychalski, Piotr\|Kmiec, Zbigniew
PMID:	29250169

48.
Journal:	J Transl Med. 2018 Jul 9;16(1):191.
Title:	The TGFbeta-signaling pathway and colorectal cancer: associations between dysregulated genes and miRNAs.
Author:	Pellatt, Andrew J\|Mullany, Lila E\|Herrick, Jennifer S\|Sakoda, Lori C\|Wolff, Roger K\|Samowitz, Wade S\|Slattery, Martha L
PMID:	29986714

49.
Journal:	Cell Death Dis. 2018 Aug 29;9(9):865.
Title:	DJ-1 promotes colorectal cancer progression through activating PLAGL2/Wnt/BMP4 axis.
Author:	Zhou, Jing\|Liu, Hao\|Zhang, Lian\|Liu, Xin\|Zhang, Chundong\|Wang, Yitao\|He, Qing\|Zhang, Ying\|Li, Yi\|Chen, Quanmei\|Zhang, Lu\|Wang, Kui\|Bu, Youquan\|Lei, Yunlong
PMID:	30158634