Primary Site >> Colorectal Cancer
Gene >> BMP4
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Ref: Oncogenic beta-catenin is required for bone morphogenetic protein 4 expression in human cancer cells. PMID: 12019147 |
Ref: Suppression of tumorigenesis and activation of Wnt signaling by bone morphogenetic protein 4 in human cancer cells. PMID: 15197354 Ref: Search for epithelial-specific mRNAs in peripheral blood of patients with colon cancer by RT-PCR. PMID: 15375555 Ref: Disruption of LTBP-4 function reduces TGF-beta activation and enhances BMP-4 signaling in the lung. PMID: 15466481 |
Ref: Gene expression profiling of colorectal adenomas and early invasive carcinomas by cDNA array analysis. PMID: 15785755 |
Ref: Foxf1 and Foxf2 control murine gut development by limiting mesenchymal Wnt signaling and promoting extracellular matrix production. PMID: 16439479 Ref: Proteomics-based validation of genomic data: applications in colorectal cancer diagnosis. PMID: 16733264 Ref: Hedgehog signaling pathway and gastrointestinal stem cell signaling network (review). PMID: 17089004 |
Ref: Bone morphogenetic protein-4 is overexpressed in colonic adenocarcinomas and promotes migration and invasion of HCT116 cells. PMID: 17275810 Ref: Gene expression analysis of hematopoietic progenitor cells identifies Dlg7 as a potential stem cell gene. PMID: 17322106 Ref: Bone morphogenetic protein-4 inhibits heat-induced apoptosis by modulating MAPK pathways in human colon cancer HCT116 cells. PMID: 17640799 |
Ref: Regulation of human Cripto-1 gene expression by TGF-beta1 and BMP-4 in embryonal and colon cancer cells. PMID: 17941089 Ref: Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer. PMID: 19011631 |
Ref: Suppression of beta-catenin signaling by liver X receptor ligands. PMID: 18983830 Ref: Overexpression of bone morphogenetic protein 4 enhances the invasiveness of Smad4-deficient human colorectal cancer cells. PMID: 19321257 |
Ref: Evaluation of germline BMP4 mutation as a cause of colorectal cancer. PMID: 20949628 Ref: Bone morphogenetic protein 4 induces differentiation of colorectal cancer stem cells and increases their response to chemotherapy in mice. PMID: 20951698 Ref: Genetic variation in the transforming growth factor-beta signaling pathway and survival after diagnosis with colon and rectal cancer. PMID: 21365634 Ref: Multiple common susceptibility variants near BMP pathway loci GREM1, BMP4, and BMP2 explain part of the missing heritability of colorectal cancer. PMID: 21655089 Ref: Colorectal cancer stem cells and cell death. PMID: 24212789 |
Ref: Genetic variation in bone morphogenetic protein and colon and rectal cancer. PMID: 21387313 Ref: The 14q22.2 colorectal cancer variant rs4444235 shows cis-acting regulation of BMP4. PMID: 22158048 Ref: Bone morphogenetic protein-4 polymorphism and colorectal cancer risk: a meta analysis. PMID: 22170598 Ref: Characterization of gene-environment interactions for colorectal cancer susceptibility loci. PMID: 22367214 Ref: Oncogenic KRAS regulates BMP4 expression in colon cancer cell lines. PMID: 22383492 Ref: Bone morphogenetic protein 4-a fascinating regulator of cancer cell behavior. PMID: 22749032 Ref: Association of Caucasian-identified variants with colorectal cancer risk in Singapore Chinese. PMID: 22879968 Ref: Hedgehog pathway signaling regulates human colon carcinoma HT-29 epithelial cell line apoptosis and cytokine secretion. PMID: 23028941 |
Ref: BMP2/BMP4 colorectal cancer susceptibility loci in northern and southern European populations. PMID: 23161572 Ref: Suppression of Src/ERK and GSK-3/beta-catenin signaling by pinosylvin inhibits the growth of human colorectal cancer cells. PMID: 23333577 |
Ref: BMP4/Thrombospondin-1 loop paracrinically inhibits tumor angiogenesis and suppresses the growth of solid tumors. PMID: 24013228 Ref: Estrogen receptor alpha or beta loss in the colon of Min/+ mice promotes crypt expansion and impairs TGFbeta and HNF3beta signaling. PMID: 24104551 Ref: Shared and independent colorectal cancer risk alleles in TGFbeta-related genes in African and European Americans. PMID: 24753543 Ref: The common variant rs4444235 near BMP4 confers genetic susceptibility of colorectal cancer: an updated meta-analysis based on a comprehensive statistical strategy. PMID: 24932582 Ref: The transcription factor GATA6 enables self-renewal of colon adenoma stem cells by repressing BMP gene expression. PMID: 24952462 Ref: Single nucleotide polymorphisms associated with colorectal cancer susceptibility and loss of heterozygosity in a Taiwanese population. PMID: 24968322 Ref: Multiple functional risk variants in a SMAD7 enhancer implicate a colorectal cancer risk haplotype. PMID: 25375357 |
Ref: Common genetic variant on BMP4 contributes to colorectal adenoma and cancer: A meta-analysis based on 15 studies. PMID: 25647270 Ref: Differential Expression of Sonic Hedgehog Protein in Human Hepatocellular Carcinoma and Intrahepatic Cholangiocarcinoma. PMID: 25740074 Ref: Effects of airborne particulate matter on alternative pre-mRNA splicing in colon cancer cells. PMID: 25863591 Ref: Dragon (repulsive guidance molecule b, RGMb) is a novel gene that promotes colorectal cancer growth. PMID: 26029998 Ref: A Candidate-Pathway Approach to Identify Gene-Environment Interactions: Analyses of Colon Cancer Risk and Survival. PMID: 26072521 Ref: Effective Inhibition of Bone Morphogenetic Protein Function by Highly Specific Llama-Derived Antibodies. PMID: 26351325 |
Ref: A subset of genetic susceptibility variants for colorectal cancer also has prognostic value. PMID: 25963333 Ref: BMP pathway suppression is an early event in inflammation-driven colon neoplasmatogenesis of uPA-deficient mice. PMID: 26358253 |
Ref: Autocrine BMP-4 Signaling Is a Therapeutic Target in Colorectal Cancer. PMID: 28611046 Ref: Therapeutic strategies against cancer stem cells in human colorectal cancer. PMID: 29250169 |
Ref: The TGFbeta-signaling pathway and colorectal cancer: associations between dysregulated genes and miRNAs. PMID: 29986714 Ref: DJ-1 promotes colorectal cancer progression through activating PLAGL2/Wnt/BMP4 axis. PMID: 30158634 |