Primary Site >> Colorectal Cancer
Gene >> BMP2
| 1. | |||||||||||
| Journal: | Pathol Int. 2001 Aug;51(8):643-8. | ||||||||||
| Title: | Expression of bone morphogenetic proteins in colon carcinoma with heterotopic ossification. | ||||||||||
| Author: | Imai, N|Iwai, A|Hatakeyama, S|Matsuzaki, K|Kitagawa, Y|Kato, S|Hokari, R|Kawaguchi, A|Nagao, S|Miyahara, T|Itoh, K|Miura, S | ||||||||||
| PMID: | 11564221 | ||||||||||
| 2. | |||||||||||
| Journal: | Gastroenterology. 2004 Jan;126(1):111-21. | ||||||||||
| Title: | Bone morphogenetic protein 2 is expressed by, and acts upon, mature epithelial cells in the colon. | ||||||||||
| Author: | Hardwick, James C H|Van Den Brink, Gijs R|Bleuming, Sylvia A|Ballester, Isabel|Van Den Brande, Jan M H|Keller, Josbert J|Offerhaus, G Johan A|Van Deventer, Sander J H|Peppelenbosch, Maikel P | ||||||||||
| PMID: | 14699493 | ||||||||||
| 3. | |||||||||||
| Journal: | Oncogene. 2006 Apr 27;25(18):2666-73. | ||||||||||
| Title: | Frequent epigenetic silencing of the bone morphogenetic protein 2 gene through methylation in gastric carcinomas. | ||||||||||
| Author: | Wen, X-Z|Akiyama, Y|Baylin, S B|Yuasa, Y | ||||||||||
| PMID: | 16314833 | ||||||||||
| 4. | |||||||||||
| Journal: | Am J Physiol Gastrointest Liver Physiol. 2006 Jul;291(1):G135-45. | ||||||||||
| Title: | Bone morphogenetic protein signaling and growth suppression in colon cancer. | ||||||||||
| Author: | Beck, Stayce E|Jung, Barbara H|Fiorino, Antonio|Gomez, Jessica|Rosario, Eunice Del|Cabrera, Betty L|Huang, Sherry C|Chow, Jimmy Y C|Carethers, John M | ||||||||||
| PMID: | 16769811 | ||||||||||
| 5. | |||||||||||
| Journal: | Cell Signal. 2007 Jul;19(7):1465-72. Epub 2007 Jan 24. | ||||||||||
| Title: | BMP-induced growth suppression in colon cancer cells is mediated by p21WAF1 stabilization and modulated by RAS/ERK. | ||||||||||
| Author: | Beck, Stayce E|Jung, Barbara H|Del Rosario, Eunice|Gomez, Jessica|Carethers, John M | ||||||||||
| PMID: | 17317101 | ||||||||||
| 6. | |||||||||||
| Journal: | Gastroenterology. 2007 Oct;133(4):1272-81. Epub 2007 Aug 14. | ||||||||||
| Title: | The effect of statins in colorectal cancer is mediated through the bone morphogenetic protein pathway. | ||||||||||
| Author: | Kodach, Liudmila L|Bleuming, Sylvia A|Peppelenbosch, Maikel P|Hommes, Daniel W|van den Brink, Gijs R|Hardwick, James C H | ||||||||||
| PMID: | 17919499 | ||||||||||
| 7. | |||||||||||
| Journal: | Cancer Detect Prev. 2007;31(4):282-95. | ||||||||||
| Title: | Identification of gene signatures for invasive colorectal tumor cells. | ||||||||||
| Author: | Wiese, Anja H|Auer, Johannes|Lassmann, Silke|Nahrig, Jorg|Rosenberg, Robert|Hofler, Heinz|Ruger, Rudiger|Werner, Martin | ||||||||||
| PMID: | 17936523 | ||||||||||
| 8. | |||||||||||
| Journal: | Cancer Res. 2008 Apr 1;68(7):2250-8. | ||||||||||
| Title: | Regulation of Id1 expression by SRC: implications for targeting of the bone morphogenetic protein pathway in cancer. | ||||||||||
| Author: | Gautschi, Oliver|Tepper, Clifford G|Purnell, Phillip R|Izumiya, Yoshihiro|Evans, Christopher P|Green, Tim P|Desprez, Pierre Y|Lara, Primo N|Gandara, David R|Mack, Philip C|Kung, Hsing-Jien | ||||||||||
| PMID: | 18381431 | ||||||||||
| 9. | |||||||||||
| Journal: | Br J Pharmacol. 2008 Jun;154(3):632-8. | ||||||||||
| Title: | Bone morphogenetic protein signalling is required for the anti-mitogenic effect of the proteasome inhibitor MG-132 on colon cancer cells. | ||||||||||
| Author: | Wu, W K K|Sung, J J Y|Wu, Y C|Li, Z J|Yu, L|Cho, C H | ||||||||||
| PMID: | 18414391 | ||||||||||
| 10. | |||||||||||
| Journal: | Neoplasia. 2009 Apr;11(4):355-64. | ||||||||||
| Title: | Discovery of fully human anti-MET monoclonal antibodies with antitumor activity against colon cancer tumor models in vivo. | ||||||||||
| Author: | van der Horst, Edward Htun|Chinn, Lawrence|Wang, Min|Velilla, Timothy|Tran, Hoang|Madrona, Yarrow|Lam, Andrew|Ji, May|Hoey, Timothy C|Sato, Aaron K | ||||||||||
| PMID: | 19308290 | ||||||||||
| 11. | |||||||||||
| Journal: | Oncol Rep. 2009 Sep;22(3):525-34. | ||||||||||
| Title: | Inhibition of PI3 kinase/Akt pathway is required for BMP2-induced EMT and invasion. | ||||||||||
| Author: | Kang, Myoung Hee|Kang, Han Na|Kim, Jung Lim|Kim, Jun Suk|Oh, Sang Cheul|Yoo, Young A | ||||||||||
| PMID: | 19639199 | ||||||||||
| 12. | |||||||||||
| Journal: | Blood. 2010 Apr 15;115(15):3136-45. | ||||||||||
| Title: | Neogenin inhibits HJV secretion and regulates BMP-induced hepcidin expression and iron homeostasis. | ||||||||||
| Author: | Lee, Dae-Hoon|Zhou, Li-Juan|Zhou, Zheng|Xie, Jian-Xin|Jung, Ji-Ung|Liu, Yu|Xi, Cai-Xia|Mei, Lin|Xiong, Wen-Cheng | ||||||||||
| PMID: | 20065295 | ||||||||||
| 13. | |||||||||||
| Journal: | Pathol Oncol Res. 2011 Jun;17(2):257-61. | ||||||||||
| Title: | Activation of the PI3K/Akt pathway mediates bone morphogenetic protein 2-induced invasion of pancreatic cancer cells Panc-1. | ||||||||||
| Author: | Chen, Xiong|Liao, Jie|Lu, YeBin|Duan, XiaoHui|Sun, WeiJia | ||||||||||
| PMID: | 20848249 | ||||||||||
| 14. | |||||||||||
| Journal: | Hum Mutat. 2011 Jan;32(1):E1928-38. | ||||||||||
| Title: | Evaluation of germline BMP4 mutation as a cause of colorectal cancer. | ||||||||||
| Author: | Lubbe, Steven J|Pittman, Alan M|Matijssen, Cornelis|Twiss, Philip|Olver, Bianca|Lloyd, Amy|Qureshi, Mobshra|Brown, Nathan|Nye, Emma|Stamp, Gordon|Blagg, Julian|Houlston, Richard S | ||||||||||
| PMID: | 20949628 | ||||||||||
| 15. | |||||||||||
| Journal: | Cancer. 2011 Sep 15;117(18):4175-83. | ||||||||||
| Title: | Genetic variation in the transforming growth factor-beta signaling pathway and survival after diagnosis with colon and rectal cancer. | ||||||||||
| Author: | Slattery, Martha L|Lundgreen, Abbie|Herrick, Jennifer S|Wolff, Roger K|Caan, Bette J | ||||||||||
| PMID: | 21365634 | ||||||||||
| 16. | |||||||||||
| Journal: | Gut. 2011 Nov;60(11):1544-53. | ||||||||||
| Title: | Statins augment the chemosensitivity of colorectal cancer cells inducing epigenetic reprogramming and reducing colorectal cancer cell 'stemness' via the bone morphogenetic protein pathway. | ||||||||||
| Author: | Kodach, Liudmila L|Jacobs, Rutger J|Voorneveld, Philip W|Wildenberg, Manon E|Verspaget, Henricus W|van Wezel, Tom|Morreau, Hans|Hommes, Daniel W|Peppelenbosch, Maikel P|van den Brink, Gijs R|Hardwick, James C H | ||||||||||
| PMID: | 21551187 | ||||||||||
| 17. | |||||||||||
| Journal: | PLoS Genet. 2011 Jun;7(6):e1002105. | ||||||||||
| Title: | Multiple common susceptibility variants near BMP pathway loci GREM1, BMP4, and BMP2 explain part of the missing heritability of colorectal cancer. | ||||||||||
| Author: | Tomlinson, Ian P M|Carvajal-Carmona, Luis G|Dobbins, Sara E|Tenesa, Albert|Jones, Angela M|Howarth, Kimberley|Palles, Claire|Broderick, Peter|Jaeger, Emma E M|Farrington, Susan|Lewis, Annabelle|Prendergast, James G D|Pittman, Alan M|Theodoratou, Evropi|Ol | ||||||||||
| PMID: | 21655089 | ||||||||||
| 18. | |||||||||||
| Journal: | Neoplasia. 2011 Aug;13(8):758-70. | ||||||||||
| Title: | Type III TGF-beta receptor enhances colon cancer cell migration and anchorage-independent growth. | ||||||||||
| Author: | Gatza, Catherine E|Holtzhausen, Alisha|Kirkbride, Kellye C|Morton, Allyson|Gatza, Michael L|Datto, Michael B|Blobe, Gerard C | ||||||||||
| PMID: | 21847367 | ||||||||||
| 19. | |||||||||||
| Journal: | Mol Med Rep. 2012 Nov;6(5):973-6. | ||||||||||
| Title: | Expression of BMP2, TLR3, TLR4 and COX2 in colorectal polyps, adenoma and adenocarcinoma. | ||||||||||
| Author: | Xiang, Li|Wang, Shiqi|Jin, Xianqing|Duan, Wenjuan|Ding, Xionghui|Zheng, Chang | ||||||||||
| PMID: | 22923219 | ||||||||||
| 20. | |||||||||||
| Journal: | PLoS One. 2012;7(8):e42407. | ||||||||||
| Title: | Association of Caucasian-identified variants with colorectal cancer risk in Singapore Chinese. | ||||||||||
| Author: | Thean, Lai Fun|Li, Hui Hua|Teo, Yik Ying|Koh, Woon-Puay|Yuan, Jian-Min|Teoh, Mei Lin|Koh, Poh Koon|Tang, Choong Leong|Cheah, Peh Yean | ||||||||||
| PMID: | 22879968 | ||||||||||
| 21. | |||||||||||
| Journal: | Gut. 2012 Jul;61(7):1041-9. | ||||||||||
| Title: | Dietary haem stimulates epithelial cell turnover by downregulating feedback inhibitors of proliferation in murine colon. | ||||||||||
| Author: | IJssennagger, Noortje|Rijnierse, Anneke|de Wit, Nicole|Jonker-Termont, Denise|Dekker, Jan|Muller, Michael|van der Meer, Roelof | ||||||||||
| PMID: | 21948946 | ||||||||||
| 22. | |||||||||||
| Journal: | Cancer Res. 2012 Apr 15;72(8):2036-44. | ||||||||||
| Title: | Characterization of gene-environment interactions for colorectal cancer susceptibility loci. | ||||||||||
| Author: | Hutter, Carolyn M|Chang-Claude, Jenny|Slattery, Martha L|Pflugeisen, Bethann M|Lin, Yi|Duggan, David|Nan, Hongmei|Lemire, Mathieu|Rangrej, Jagadish|Figueiredo, Jane C|Jiao, Shuo|Harrison, Tabitha A|Liu, Yan|Chen, Lin S|Stelling, Deanna L|Warnick, Greg S|H | ||||||||||
| PMID: | 22367214 | ||||||||||
| 23. | |||||||||||
| Journal: | Hum Genet. 2012 Feb;131(2):217-34. | ||||||||||
| Title: | Meta-analysis of new genome-wide association studies of colorectal cancer risk. | ||||||||||
| Author: | Peters, Ulrike|Hutter, Carolyn M|Hsu, Li|Schumacher, Fredrick R|Conti, David V|Carlson, Christopher S|Edlund, Christopher K|Haile, Robert W|Gallinger, Steven|Zanke, Brent W|Lemire, Mathieu|Rangrej, Jagadish|Vijayaraghavan, Raakhee|Chan, Andrew T|Hazra, Ad | ||||||||||
| PMID: | 21761138 | ||||||||||
| 24. | |||||||||||
| Journal: | Int J Cancer. 2012 Feb 1;130(3):653-64. | ||||||||||
| Title: | Genetic variation in bone morphogenetic protein and colon and rectal cancer. | ||||||||||
| Author: | Slattery, Martha L|Lundgreen, Abbie|Herrick, Jennifer S|Kadlubar, Susan|Caan, Bette J|Potter, John D|Wolff, Roger K | ||||||||||
| PMID: | 21387313 | ||||||||||
| 25. | |||||||||||
| Journal: | Gastroenterol Res Pract. 2012;2012:895462. | ||||||||||
| Title: | E. coli-produced BMP-2 as a chemopreventive strategy for colon cancer: a proof-of-concept study. | ||||||||||
| Author: | Yuvaraj, Saravanan|Al-Lahham, Sa'ad H|Somasundaram, Rajesh|Figaroa, Patrick A|Peppelenbosch, Maikel P|Bos, Nicolaas A | ||||||||||
| PMID: | 22315590 | ||||||||||
| 26. | |||||||||||
| Journal: | Carcinogenesis. 2013 Feb;34(2):314-8. | ||||||||||
| Title: | BMP2/BMP4 colorectal cancer susceptibility loci in northern and southern European populations. | ||||||||||
| Author: | Fernandez-Rozadilla, Ceres|Palles, Claire|Carvajal-Carmona, Luis|Peterlongo, Paolo|Nici, Carmela|Veneroni, Silvia|Pinheiro, Manuela|Teixeira, Manuel R|Moreno, Victor|Lamas, Maria-Jesus|Baiget, Montserrat|Lopez-Fernandez, L A|Gonzalez, Dolors|Brea-Fernande | ||||||||||
| PMID: | 23161572 | ||||||||||
| 27. | |||||||||||
| Journal: | Gene. 2013 Jun 10;522(1):75-83. | ||||||||||
| Title: | Evidence of colorectal cancer risk associated variant Lys25Ser in the proximity of human bone morphogenetic protein 2. | ||||||||||
| Author: | Khan, Wajahatullah|Abduljaleel, Zainularifeen|Alanazi, Mohammed|Elrobh, Mohamed | ||||||||||
| PMID: | 23537995 | ||||||||||
| 28. | |||||||||||
| Journal: | Gastroenterology. 2013 Oct;145(4):820-30.e10. | ||||||||||
| Title: | Progastrin stimulates colonic cell proliferation via CCK2R- and beta-arrestin-dependent suppression of BMP2. | ||||||||||
| Author: | Jin, Guangchun|Westphalen, C Benedikt|Hayakawa, Yoku|Worthley, Daniel L|Asfaha, Samuel|Yang, Xiangdong|Chen, Xiaowei|Si, Yiling|Wang, Hongshan|Tailor, Yagnesh|Friedman, Richard A|Wang, Timothy C | ||||||||||
| PMID: | 23891976 | ||||||||||
| 29. | |||||||||||
| Journal: | Oncol Rep. 2014 Sep;32(3):1013-20. | ||||||||||
| Title: | Bone morphogenetic protein 2 inhibits the proliferation and growth of human colorectal cancer cells. | ||||||||||
| Author: | Zhang, Yunyuan|Chen, Xian|Qiao, Min|Zhang, Bing-Qiang|Wang, Ning|Zhang, Zhonglin|Liao, Zhan|Zeng, Liyi|Deng, Youlin|Deng, Fang|Zhang, Junhui|Yin, Liangjun|Liu, Wei|Zhang, Qian|Ya, Zhengjian|Ye, Jixing|Wang, Zhongliang|Zhou, Lan|Luu, Hue H|Haydon, Rex C|He | ||||||||||
| PMID: | 24993644 | ||||||||||
| 30. | |||||||||||
| Journal: | Thorac Cancer. 2014 Jan;5(1):14-24. | ||||||||||
| Title: | Increased hepcidin expression in non-small cell lung cancer tissue and serum is associated with clinical stage. | ||||||||||
| Author: | Chen, Qian|Wang, Li|Ma, Yuchao|Wu, Xianning|Jin, Longyu|Yu, Fenglei | ||||||||||
| PMID: | 26766967 | ||||||||||
| 31. | |||||||||||
| Journal: | Mol Cancer Ther. 2015 Nov;14(11):2527-40. | ||||||||||
| Title: | Effective Inhibition of Bone Morphogenetic Protein Function by Highly Specific Llama-Derived Antibodies. | ||||||||||
| Author: | Calpe, Silvia|Wagner, Koen|El Khattabi, Mohamed|Rutten, Lucy|Zimberlin, Cheryl|Dolk, Edward|Verrips, C Theo|Medema, Jan Paul|Spits, Hergen|Krishnadath, Kausilia K | ||||||||||
| PMID: | 26351325 | ||||||||||
| 32. | |||||||||||
| Journal: | Tumour Biol. 2015 Dec;36(12):9475-86. | ||||||||||
| Title: | BMP-2 induces motility and invasiveness by promoting colon cancer stemness through STAT3 activation. | ||||||||||
| Author: | Kim, Bo Ram|Oh, Sang Cheul|Lee, Dae-Hee|Kim, Jung Lim|Lee, Suk Young|Kang, Myoung Hee|Lee, Sun Il|Kang, Sanghee|Joung, Sung Yup|Min, Byung Wook | ||||||||||
| PMID: | 26124007 | ||||||||||
| 33. | |||||||||||
| Journal: | BMC Med Genomics. 2016 Apr 23;9(1):21. | ||||||||||
| Title: | Impact of polymorphisms in microRNA biogenesis genes on colon cancer risk and microRNA expression levels: a population-based, case-control study. | ||||||||||
| Author: | Mullany, Lila E|Herrick, Jennifer S|Wolff, Roger K|Buas, Matthew F|Slattery, Martha L | ||||||||||
| PMID: | 27107574 | ||||||||||
| 34. | |||||||||||
| Journal: | J Neurosci. 2016 May 25;36(21):5833-49. | ||||||||||
| Title: | Neogenin Promotes BMP2 Activation of YAP and Smad1 and Enhances Astrocytic Differentiation in Developing Mouse Neocortex. | ||||||||||
| Author: | Huang, Zhihui|Sun, Dong|Hu, Jin-Xia|Tang, Fu-Lei|Lee, Dae-Hoon|Wang, Ying|Hu, Guoqing|Zhu, Xiao-Juan|Zhou, Jiliang|Mei, Lin|Xiong, Wen-Cheng | ||||||||||
| PMID: | 27225772 | ||||||||||
| 35. | |||||||||||
| Journal: | Cancer Cell Int. 2016 Sep 29;16:77. | ||||||||||
| Title: | Bone morphogenetic protein 2 (BMP2) induces growth suppression and enhances chemosensitivity of human colon cancer cells. | ||||||||||
| Author: | Vishnubalaji, Radhakrishnan|Yue, Shijun|Alfayez, Musaad|Kassem, Moustapha|Liu, Fei-Fei|Aldahmash, Abdullah|Alajez, Nehad M | ||||||||||
| PMID: | 27708551 | ||||||||||
| 36. | |||||||||||
| Journal: | Pharm Biol. 2017 Dec;55(1):1239-1248. | ||||||||||
| Title: | Fatty acid composition and anticancer activity in colon carcinoma cell lines of Prunus dulcis seed oil. | ||||||||||
| Author: | Mericli, Filiz|Becer, Eda|Kabadayi, Hilal|Hanoglu, Azmi|Yigit Hanoglu, Duygu|Ozkum Yavuz, Dudu|Ozek, Temel|Vatansever, Seda | ||||||||||
| PMID: | 28262033 | ||||||||||
| 37. | |||||||||||
| Journal: | BMC Genet. 2017 Dec 28;18(Suppl 1):117. | ||||||||||
| Title: | Upregulation of NETO2 gene in colorectal cancer. | ||||||||||
| Author: | Fedorova, Maria S|Snezhkina, Anastasiya V|Pudova, Elena A|Abramov, Ivan S|Lipatova, Anastasiya V|Kharitonov, Sergey L|Sadritdinova, Asiya F|Nyushko, Kirill M|Klimina, Kseniya M|Belyakov, Mikhail M|Slavnova, Elena N|Melnikova, Nataliya V|Chernichenko, Mari | ||||||||||
| PMID: | 29297384 | ||||||||||
| 38. | |||||||||||
| Journal: | Mol Carcinog. 2018 May;57(5):664-677. | ||||||||||
| Title: | Abrus agglutinin stimulates BMP-2-dependent differentiation through autophagic degradation of beta-catenin in colon cancer stem cells. | ||||||||||
| Author: | Panda, Prashanta K|Naik, Prajna P|Praharaj, Prakash P|Meher, Biswa R|Gupta, Piyush K|Verma, Rama S|Maiti, Tapas K|Shanmugam, Muthu K|Chinnathambi, Arunachalam|Alharbi, Sulaiman A|Sethi, Gautam|Agarwal, Rajesh|Bhutia, Sujit K | ||||||||||
| PMID: | 29457276 | ||||||||||
| 39. | |||||||||||
| Journal: | J Transl Med. 2018 Jul 9;16(1):191. | ||||||||||
| Title: | The TGFbeta-signaling pathway and colorectal cancer: associations between dysregulated genes and miRNAs. | ||||||||||
| Author: | Pellatt, Andrew J|Mullany, Lila E|Herrick, Jennifer S|Sakoda, Lori C|Wolff, Roger K|Samowitz, Wade S|Slattery, Martha L | ||||||||||
| PMID: | 29986714 | ||||||||||
| 40. | |||||||||||
| Journal: | Cell Mol Gastroenterol Hepatol. 2018 May 24;6(3):257-276. | ||||||||||
| Title: | Epithelial Smad4 Deletion Up-Regulates Inflammation and Promotes Inflammation-Associated Cancer. | ||||||||||
| Author: | Means, Anna L|Freeman, Tanner J|Zhu, Jing|Woodbury, Luke G|Marincola-Smith, Paula|Wu, Chao|Meyer, Anne R|Weaver, Connie J|Padmanabhan, Chandrasekhar|An, Hanbing|Zi, Jinghuan|Wessinger, Bronson C|Chaturvedi, Rupesh|Brown, Tasia D|Deane, Natasha G|Coffey, R | ||||||||||
| PMID: | 30109253 | ||||||||||