Primary Site >> Colorectal Cancer
Gene >> BMP2
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Ref: Expression of bone morphogenetic proteins in colon carcinoma with heterotopic ossification. PMID: 11564221 |
Ref: Bone morphogenetic protein 2 is expressed by, and acts upon, mature epithelial cells in the colon. PMID: 14699493 |
Ref: Frequent epigenetic silencing of the bone morphogenetic protein 2 gene through methylation in gastric carcinomas. PMID: 16314833 Ref: Bone morphogenetic protein signaling and growth suppression in colon cancer. PMID: 16769811 |
Ref: BMP-induced growth suppression in colon cancer cells is mediated by p21WAF1 stabilization and modulated by RAS/ERK. PMID: 17317101 Ref: The effect of statins in colorectal cancer is mediated through the bone morphogenetic protein pathway. PMID: 17919499 Ref: Identification of gene signatures for invasive colorectal tumor cells. PMID: 17936523 |
Ref: Regulation of Id1 expression by SRC: implications for targeting of the bone morphogenetic protein pathway in cancer. PMID: 18381431 Ref: Bone morphogenetic protein signalling is required for the anti-mitogenic effect of the proteasome inhibitor MG-132 on colon cancer cells. PMID: 18414391 |
Ref: Discovery of fully human anti-MET monoclonal antibodies with antitumor activity against colon cancer tumor models in vivo. PMID: 19308290 Ref: Inhibition of PI3 kinase/Akt pathway is required for BMP2-induced EMT and invasion. PMID: 19639199 |
Ref: Neogenin inhibits HJV secretion and regulates BMP-induced hepcidin expression and iron homeostasis. PMID: 20065295 |
Ref: Activation of the PI3K/Akt pathway mediates bone morphogenetic protein 2-induced invasion of pancreatic cancer cells Panc-1. PMID: 20848249 Ref: Evaluation of germline BMP4 mutation as a cause of colorectal cancer. PMID: 20949628 Ref: Genetic variation in the transforming growth factor-beta signaling pathway and survival after diagnosis with colon and rectal cancer. PMID: 21365634 Ref: Statins augment the chemosensitivity of colorectal cancer cells inducing epigenetic reprogramming and reducing colorectal cancer cell 'stemness' via the bone morphogenetic protein pathway. PMID: 21551187 Ref: Multiple common susceptibility variants near BMP pathway loci GREM1, BMP4, and BMP2 explain part of the missing heritability of colorectal cancer. PMID: 21655089 Ref: Type III TGF-beta receptor enhances colon cancer cell migration and anchorage-independent growth. PMID: 21847367 |
Ref: Genetic variation in bone morphogenetic protein and colon and rectal cancer. PMID: 21387313 Ref: Meta-analysis of new genome-wide association studies of colorectal cancer risk. PMID: 21761138 Ref: Dietary haem stimulates epithelial cell turnover by downregulating feedback inhibitors of proliferation in murine colon. PMID: 21948946 Ref: E. coli-produced BMP-2 as a chemopreventive strategy for colon cancer: a proof-of-concept study. PMID: 22315590 Ref: Characterization of gene-environment interactions for colorectal cancer susceptibility loci. PMID: 22367214 Ref: Association of Caucasian-identified variants with colorectal cancer risk in Singapore Chinese. PMID: 22879968 Ref: Expression of BMP2, TLR3, TLR4 and COX2 in colorectal polyps, adenoma and adenocarcinoma. PMID: 22923219 |
Ref: BMP2/BMP4 colorectal cancer susceptibility loci in northern and southern European populations. PMID: 23161572 Ref: Evidence of colorectal cancer risk associated variant Lys25Ser in the proximity of human bone morphogenetic protein 2. PMID: 23537995 Ref: Progastrin stimulates colonic cell proliferation via CCK2R- and beta-arrestin-dependent suppression of BMP2. PMID: 23891976 |
Ref: Bone morphogenetic protein 2 inhibits the proliferation and growth of human colorectal cancer cells. PMID: 24993644 Ref: Increased hepcidin expression in non-small cell lung cancer tissue and serum is associated with clinical stage. PMID: 26766967 |
Ref: BMP-2 induces motility and invasiveness by promoting colon cancer stemness through STAT3 activation. PMID: 26124007 Ref: Effective Inhibition of Bone Morphogenetic Protein Function by Highly Specific Llama-Derived Antibodies. PMID: 26351325 |
Ref: Impact of polymorphisms in microRNA biogenesis genes on colon cancer risk and microRNA expression levels: a population-based, case-control study. PMID: 27107574 Ref: Neogenin Promotes BMP2 Activation of YAP and Smad1 and Enhances Astrocytic Differentiation in Developing Mouse Neocortex. PMID: 27225772 Ref: Bone morphogenetic protein 2 (BMP2) induces growth suppression and enhances chemosensitivity of human colon cancer cells. PMID: 27708551 |
Ref: Fatty acid composition and anticancer activity in colon carcinoma cell lines of Prunus dulcis seed oil. PMID: 28262033 Ref: Upregulation of NETO2 gene in colorectal cancer. PMID: 29297384 |
Ref: Abrus agglutinin stimulates BMP-2-dependent differentiation through autophagic degradation of beta-catenin in colon cancer stem cells. PMID: 29457276 Ref: The TGFbeta-signaling pathway and colorectal cancer: associations between dysregulated genes and miRNAs. PMID: 29986714 Ref: Epithelial Smad4 Deletion Up-Regulates Inflammation and Promotes Inflammation-Associated Cancer. PMID: 30109253 |