Primary Site >> Colorectal Cancer

Gene >> BIRC3

Journal: Oncogene. 1998 Dec 24;17(25):3247-59.
Title: The inhibitors of apoptosis (IAPs) and their emerging role in cancer.
Author: LaCasse, E C|Baird, S|Korneluk, R G|MacKenzie, A E
PMID: 9916987
Journal: Proc Natl Acad Sci U S A. 2003 Jul 22;100(15):8921-6.
Title: Inhibition of apoptosis in normal and transformed intestinal epithelial cells by cAMP through induction of inhibitor of apoptosis protein (IAP)-2.
Author: Nishihara, Hiroshi|Kizaka-Kondoh, Shinae|Insel, Paul A|Eckmann, Lars
PMID: 12837940
Journal: Pathol Res Pract. 2003;199(11):723-31.
Title: Subcellular expression of c-IAP1 and c-IAP2 in colorectal cancers: relationships with clinicopathological features and prognosis.
Author: Ponnelle, Tibor|Chapusot, Caroline|Martin, Laurent|Bonithon-Kopp, Claire|Bouvier, Anne Marie|Plenchette, Stephanie|Rageot, David|Faivre, Jean|Solary, Eric|Piard, Francoise
PMID: 14708638
Journal: J Biol Chem. 2004 Jun 18;279(25):26176-83. Epub 2004 Apr 12.
Title: Cyclic AMP promotes cAMP-responsive element-binding protein-dependent induction of cellular inhibitor of apoptosis protein-2 and suppresses apoptosis of colon cancer cells through ERK1/2 and p38 MAPK.
Author: Nishihara, Hiroshi|Hwang, Michael|Kizaka-Kondoh, Shinae|Eckmann, Lars|Insel, Paul A
PMID: 15078890
Journal: Cancer Immunol Immunother. 2004 Sep;53(9):770-6. Epub 2004 May 11.
Title: Expression of IAP family proteins in colon cancers from patients with different age groups.
Author: Endo, T|Abe, S|Seidlar, H B K|Nagaoka, S|Takemura, T|Utsuyama, M|Kitagawa, M|Hirokawa, K
PMID: 15138717
Journal: Clin Cancer Res. 2004 May 15;10(10):3333-41.
Title: Enhanced chemosensitivity to irinotecan by RNA interference-mediated down-regulation of the nuclear factor-kappaB p65 subunit.
Author: Guo, Jun|Verma, Udit N|Gaynor, Richard B|Frenkel, Eugene P|Becerra, Carlos R
PMID: 15161687
Journal: Clin Cancer Res. 2005 Aug 1;11(15):5451-61.
Title: Analysis of apoptosis protein expression in early-stage colorectal cancer suggests opportunities for new prognostic biomarkers.
Author: Krajewska, Maryla|Kim, Hoguen|Kim, Chul|Kang, Haeyoun|Welsh, Kate|Matsuzawa, Shu-Ichi|Tsukamoto, Michelle|Thomas, Ronald G|Assa-Munt, Nuria|Piao, Zhe|Suzuki, Koichi|Perucho, Manuel|Krajewski, Stan|Reed, John C
PMID: 16061861
Journal: Gut. 2006 Feb;55(2):234-42. Epub 2005 Aug 23.
Title: Increased expression of high mobility group box 1 (HMGB1) is associated with an elevated level of the antiapoptotic c-IAP2 protein in human colon carcinomas.
Author: Volp, K|Brezniceanu, M-L|Bosser, S|Brabletz, T|Kirchner, T|Gottel, D|Joos, S|Zornig, M
PMID: 16118352
Journal: Apoptosis. 2007 Sep;12(9):1671-80.
Title: Gene expression profiling reveals two separate mechanisms regulating apoptosis in rectal carcinomas in vivo.
Author: de Bruin, Elza C|van de Pas, Simone|van de Velde, Cornelis J H|van Krieken, J Han J M|Peltenburg, Lucy T C|Marijnen, Corrie A M|Medema, Jan Paul
PMID: 17610066
Journal: Cancer Cell. 2007 Jul;12(1):4-6.
Title: Clearing the TRAIL for Cancer Therapy.
Author: Hall, Mark A|Cleveland, John L
PMID: 17613431
Journal: Int J Oncol. 2007 Dec;31(6):1491-500.
Title: Apoptosis, cell cycle progression and gene expression in TP53-depleted HCT116 colon cancer cells in response to short-term 5-fluorouracil treatment.
Author: Adamsen, Birgitte Lid|Kravik, Katherine L|Clausen, Ole P F|De Angelis, Paula M
PMID: 17982676
Journal: Oncogene. 2008 Feb 14;27(8):1122-34. Epub 2007 Aug 20.
Title: The apoptosis-inducing effect of gastrin on colorectal cancer cells relates to an increased IEX-1 expression mediating NF-kappa B inhibition.
Author: Sebens Muerkoster, S|Rausch, A V|Isberner, A|Minkenberg, J|Blaszczuk, E|Witt, M|Folsch, U R|Schmitz, F|Schafer, H|Arlt, A
PMID: 17704804
Journal: Drug Resist Updat. 2009 Jun;12(3):55-64.
Title: Targeting apoptosis as an approach for gastrointestinal cancer therapy.
Author: Qiao, Liang|Wong, Benjamin C Y
PMID: 19278896
Journal: Cancer Sci. 2009 May;100(5):903-13.
Title: Down-regulation of cIAP2 enhances 5-FU sensitivity through the apoptotic pathway in human colon cancer cells.
Author: Karasawa, Hideaki|Miura, Koh|Fujibuchi, Wataru|Ishida, Kazuyuki|Kaneko, Naoyuki|Kinouchi, Makoto|Okabe, Mitsunori|Ando, Toshinori|Murata, Yukio|Sasaki, Hiroyuki|Takami, Kazuhiro|Yamamura, Akihiro|Shibata, Chikashi|Sasaki, Iwao
PMID: 19302291
Journal: Expert Opin Ther Targets. 2009 Nov;13(11):1333-45.
Title: cIAP2 as a therapeutic target in colorectal cancer and other malignancies.
Author: Miura, Koh|Karasawa, Hideaki|Sasaki, Iwao
PMID: 19793002
Journal: J Med Food. 2010 Feb;13(1):6-12.
Title: Antiproliferative effect of chitosan-added kimchi in HT-29 human colon carcinoma cells.
Author: Kong, Chang-Suk|Bahn, Young-Eun|Kim, Boh-Kyung|Lee, Kang-Yoon|Park, Kun-Young
PMID: 20136430
Journal: Mol Cancer Ther. 2010 Aug;9(8):2196-207.
Title: Gamma-tocotrienol promotes TRAIL-induced apoptosis through reactive oxygen species/extracellular signal-regulated kinase/p53-mediated upregulation of death receptors.
Author: Kannappan, Ramaswamy|Ravindran, Jayaraj|Prasad, Sahdeo|Sung, Bokyung|Yadav, Vivek R|Reuter, Simone|Chaturvedi, Madan M|Aggarwal, Bharat B
PMID: 20682650
Journal: Int J Radiat Oncol Biol Phys. 2011 Jul 1;80(3):705-11.
Title: Nuclear factor kappa-light chain-enhancer of activated B cells is activated by radiotherapy and is prognostic for overall survival in patients with rectal cancer treated with preoperative fluorouracil-based chemoradiotheraphy.
Author: O'Neil, Bert H|Funkhouser, William K|Calvo, Benjamin F|Meyers, Michael O|Kim, Hong Jin|Goldberg, Richard M|Bernard, Stephen A|Caskey, Laura|Deal, Allison M|Wright, Fred|Baldwin, Albert S|Tepper, Joel E
PMID: 20630669
Journal: Surg Today. 2011 Feb;41(2):175-82.
Title: Inhibitor of apoptosis protein family as diagnostic markers and therapeutic targets of colorectal cancer.
Author: Miura, Koh|Fujibuchi, Wataru|Ishida, Kazuyuki|Naitoh, Takeshi|Ogawa, Hitoshi|Ando, Toshinori|Yazaki, Nobuki|Watanabe, Kazuhiro|Haneda, Sho|Shibata, Chikashi|Sasaki, Iwao
PMID: 21264751
Journal: Mol Cancer Ther. 2011 May;10(5):902-14.
Title: Therapeutic potential and molecular mechanism of a novel, potent, nonpeptide, Smac mimetic SM-164 in combination with TRAIL for cancer treatment.
Author: Lu, Jianfeng|McEachern, Donna|Sun, Haiying|Bai, Longchuan|Peng, Yuefeng|Qiu, Su|Miller, Rebecca|Liao, Jinhui|Yi, Han|Liu, Meilan|Bellail, Anita|Hao, Chunhai|Sun, Shi-Yong|Ting, Adrian T|Wang, Shaomeng
PMID: 21372226
Journal: Biomed Pharmacother. 2011 Jun;65(3):175-82.
Title: Concomitant activation of caspase-9 and down-regulation of IAP proteins as a mechanism of apoptotic death in HepG2, T47D and HCT-116 cells upon exposure to a derivative from 4-aryl-4H-chromenes family.
Author: Mahdavi, Majid|Davoodi, Jamshid|Zali, Mohammad Reza|Foroumadi, Alireza
PMID: 21565459
Journal: Oncogene. 2013 May 9;32(19):2380-9.
Title: An apoptosis-independent role of SMAC in tumor suppression.
Author: Qiu, W|Liu, H|Sebastini, A|Sun, Q|Wang, H|Zhang, L|Yu, J
PMID: 22751125
Journal: Clin Cancer Res. 2013 Dec 15;19(24):6787-801.
Title: A personalized preclinical model to evaluate the metastatic potential of patient-derived colon cancer initiating cells.
Author: Puig, Isabel|Chicote, Irene|Tenbaum, Stephan P|Arques, Oriol|Herance, Jose Raul|Gispert, Juan D|Jimenez, Jose|Landolfi, Stefania|Caci, Karina|Allende, Helena|Mendizabal, Leire|Moreno, Debora|Charco, Ramon|Espin, Eloy|Prat, Aleix|Elez, Maria Elena|Argiles,
PMID: 24170545
Journal: Inflamm Bowel Dis. 2013 Mar;19(3):461-70.
Title: Gene signature distinguishes patients with chronic ulcerative colitis harboring remote neoplastic lesions.
Author: Pekow, Joel|Dougherty, Urszula|Huang, Yong|Gometz, Edward|Nathanson, Jeff|Cohen, Greg|Levy, Shawn|Kocherginsky, Masha|Venu, Nanda|Westerhoff, Maria|Hart, John|Noffsinger, Amy E|Hanauer, Stephen B|Hurst, Roger D|Fichera, Alessandro|Joseph, Loren J|Liu, Qia
PMID: 23388545
Journal: Mol Med Rep. 2014 Jan;9(1):249-54.
Title: Berberine enhances chemosensitivity to irinotecan in colon cancer via inhibition of NFkappaB.
Author: Yu, Meiling|Tong, Xuhui|Qi, Benquan|Qu, Hongdang|Dong, Shuying|Yu, Binbin|Zhang, Naiju|Tang, Nan|Wang, Lingzhi|Zhang, Cuiling
PMID: 24173769
Journal: Cell Death Dis. 2014 Feb 27;5:e1085.
Title: The LEF1/CYLD axis and cIAPs regulate RIP1 deubiquitination and trigger apoptosis in selenite-treated colorectal cancer cells.
Author: Wu, P|Shi, K J|An, J J|Ci, Y L|Li, F|Hui, K Y|Yang, Y|Xu, C M
PMID: 24577083
Journal: BMC Cancer. 2014 Aug 18;14:599.
Title: Variable NF-kappaB pathway responses in colon cancer cells treated with chemotherapeutic drugs.
Author: Samuel, Temesgen|Fadlalla, Khalda|Gales, Dominique N|Putcha, Balananda D K|Manne, Upender
PMID: 25134433
Journal: PLoS One. 2014 Sep 8;9(9):e107165.
Title: EGFR-targeted TRAIL and a Smac mimetic synergize to overcome apoptosis resistance in KRAS mutant colorectal cancer cells.
Author: Moller, Yvonne|Siegemund, Martin|Beyes, Sven|Herr, Ricarda|Lecis, Daniele|Delia, Domenico|Kontermann, Roland|Brummer, Tilman|Pfizenmaier, Klaus|Olayioye, Monilola A
PMID: 25198428
Journal: Anticancer Res. 2015 Dec;35(12):6577-81.
Title: Microarray Analysis of Gene Expression at the Tumor Front of Colon Cancer.
Author: Kobayashi, Takaaki|Masaki, Tadahiko|Nozaki, Eriko|Sugiyama, Masanori|Nagashima, Fumio|Furuse, Junji|Onishi, Hiroaki|Watanabe, Takashi|Ohkura, Yasuo
PMID: 26637872
Journal: J Exp Clin Cancer Res. 2015 Nov 21;34:142.
Title: A-kinase anchor protein 4 (AKAP4) a promising therapeutic target of colorectal cancer.
Author: Jagadish, Nirmala|Parashar, Deepak|Gupta, Namita|Agarwal, Sumit|Purohit, Sapna|Kumar, Vikash|Sharma, Aditi|Fatima, Rukhsar|Topno, Amos Prashant|Shaha, Chandrima|Suri, Anil
PMID: 26590805
Journal: Radiat Oncol. 2015 Sep 17;10:198.
Title: The SMAC mimetic BV6 sensitizes colorectal cancer cells to ionizing radiation by interfering with DNA repair processes and enhancing apoptosis.
Author: Hehlgans, Stephanie|Oppermann, Julius|Reichert, Sebastian|Fulda, Simone|Rodel, Claus|Rodel, Franz
PMID: 26383618
Journal: Radiat Oncol. 2015 Jun 13;10:131.
Title: High levels of X-linked Inhibitor-of-Apoptosis Protein (XIAP) are indicative of radio chemotherapy resistance in rectal cancer.
Author: Flanagan, L|Kehoe, J|Fay, J|Bacon, O|Lindner, A U|Kay, E W|Deasy, J|McNamara, D A|Prehn, J H M
PMID: 26071313
Journal: Int J Clin Oncol. 2015 Feb;20(1):117-25.
Title: Usefulness of alternate-day administration of S-1 and leucovorin in a xenograft mouse model of colorectal cancer: a shorter drug-free interval leads to more efficient antitumor effects.
Author: Komura, Toshihiro|Miura, Koh|Shirasaka, Tetsuhiko|Ohnuma, Shinobu|Shimada, Miki|Kajiwara, Taiki|Fujishima, Fumiyoshi|Philchenkov, Alex|Nakagawa, Kei|Kudoh, Katsuyoshi|Haneda, Sho|Toshima, Masahide|Kohyama, Atsushi|Musha, Hiroaki|Naitoh, Takeshi|Shibata, C
PMID: 24802097
Journal: Mucosal Immunol. 2016 Jan;9(1):146-58.
Title: A critical role for cellular inhibitor of protein 2 (cIAP2) in colitis-associated colorectal cancer and intestinal homeostasis mediated by the inflammasome and survival pathways.
Author: Dagenais, M|Dupaul-Chicoine, J|Champagne, C|Skeldon, A|Morizot, A|Saleh, M
PMID: 26037070
Journal: PLoS One. 2016 May 12;11(5):e0155660.
Title: Systematic Analysis of Gene Expression Alterations and Clinical Outcomes for Long-Chain Acyl-Coenzyme A Synthetase Family in Cancer.
Author: Chen, Wei-Ching|Wang, Chih-Yang|Hung, Yu-Hsuan|Weng, Tzu-Yang|Yen, Meng-Chi|Lai, Ming-Derg
PMID: 27171439
Journal: Zhonghua Bing Li Xue Za Zhi. 2016 Jun 8;45(6):401-6.
Title: [Roles of glucose-regulated protein 78 in proliferation and migration of human colorectal carcinoma cell line RKO].
Author: Ji, Q X|Liu, L L|Li, L|Xing, X M
PMID: 27256049
Journal: Sci Rep. 2016 Nov 9;6:36532.
Title: Death receptor 5 (DR5) and a 5-gene apoptotic biomarker panel with significant differential diagnostic potential in colorectal cancer.
Author: Devetzi, Marina|Kosmidou, Vivian|Vlassi, Margarita|Perysinakis, Iraklis|Aggeli, Chrysanthi|Choreftaki, Theodosia|Zografos, Georgios N|Pintzas, Alexander
PMID: 27827395
Journal: Gastroenterology. 2017 Mar;152(4):867-879.
Title: Inhibitor of Apoptosis Protein-1 Regulates Tumor Necrosis Factor-Mediated Destruction of Intestinal Epithelial Cells.
Author: Grabinger, Thomas|Bode, Konstantin J|Demgenski, Janine|Seitz, Carina|Delgado, M Eugenia|Kostadinova, Feodora|Reinhold, Cindy|Etemadi, Nima|Wilhelm, Sabine|Schweinlin, Matthias|Hanggi, Kay|Knop, Janin|Hauck, Christof|Walles, Heike|Silke, John|Wajant, Haral
PMID: 27889570
Journal: J Cancer Prev. 2017 Jun;22(2):98-102.
Title: Evaluation of the Expression of the Inhibitor of Apoptosis Protein Family and Human Telomerase Reverse Transcriptase in Patients With Advanced Colorectal Adenoma.
Author: Choi, Joon Young|Yoon, Hyuk|Na, Gyeongjae|Choi, Yoon Jin|Shin, Cheol Min|Park, Young Soo|Kim, Nayoung|Lee, Dong Ho
PMID: 28698863
Journal: Int Immunopharmacol. 2018 Jun;59:375-383.
Title: Toll-like receptor 2 stimulation promotes colorectal cancer cell growth via PI3K/Akt and NF-kappaB signaling pathways.
Author: Liu, You Dong|Ji, Cheng Bo|Li, Shan Bao|Yan, Feng|Gu, Qi Sheng|Balic, Jesse J|Yu, Liang|Li, Ji Kun
PMID: 29689497
Journal: Int J Biol Macromol. 2018 Oct 1;117:1011-1016.
Title: Transcriptomic analysis reveals the underlying pro-malignant functions of Gankyrin for colorectal cancer via affecting tumor necrosis factor pathway.
Author: Xu, Baojin|Li, Shenglong|Lv, Wu|Wang, Yue|Li, Xiaoyan|Zhang, Lina|Lin, Jie
PMID: 29883699
Journal: Int J Oncol. 2018 Sep;53(3):1269-1278.
Title: Tristetraprolin activation by resveratrol inhibits the proliferation and metastasis of colorectal cancer cells.
Author: Lee, Se-Ra|Jin, Hua|Kim, Won-Tae|Kim, Won-Jung|Kim, Sung Zoo|Leem, Sun-Hee|Kim, Soo Mi
PMID: 29956753