Primary Site >> Colorectal Cancer
Gene >> BIRC3
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Ref: The inhibitors of apoptosis (IAPs) and their emerging role in cancer. PMID: 9916987 |
Ref: Inhibition of apoptosis in normal and transformed intestinal epithelial cells by cAMP through induction of inhibitor of apoptosis protein (IAP)-2. PMID: 12837940 Ref: Subcellular expression of c-IAP1 and c-IAP2 in colorectal cancers: relationships with clinicopathological features and prognosis. PMID: 14708638 |
Ref: Cyclic AMP promotes cAMP-responsive element-binding protein-dependent induction of cellular inhibitor of apoptosis protein-2 and suppresses apoptosis of colon cancer cells through ERK1/2 and p38 MAPK. PMID: 15078890 Ref: Expression of IAP family proteins in colon cancers from patients with different age groups. PMID: 15138717 Ref: Enhanced chemosensitivity to irinotecan by RNA interference-mediated down-regulation of the nuclear factor-kappaB p65 subunit. PMID: 15161687 |
Ref: Analysis of apoptosis protein expression in early-stage colorectal cancer suggests opportunities for new prognostic biomarkers. PMID: 16061861 |
Ref: Increased expression of high mobility group box 1 (HMGB1) is associated with an elevated level of the antiapoptotic c-IAP2 protein in human colon carcinomas. PMID: 16118352 |
Ref: Gene expression profiling reveals two separate mechanisms regulating apoptosis in rectal carcinomas in vivo. PMID: 17610066 Ref: Clearing the TRAIL for Cancer Therapy. PMID: 17613431 Ref: Apoptosis, cell cycle progression and gene expression in TP53-depleted HCT116 colon cancer cells in response to short-term 5-fluorouracil treatment. PMID: 17982676 |
Ref: The apoptosis-inducing effect of gastrin on colorectal cancer cells relates to an increased IEX-1 expression mediating NF-kappa B inhibition. PMID: 17704804 |
Ref: Targeting apoptosis as an approach for gastrointestinal cancer therapy. PMID: 19278896 Ref: Down-regulation of cIAP2 enhances 5-FU sensitivity through the apoptotic pathway in human colon cancer cells. PMID: 19302291 Ref: cIAP2 as a therapeutic target in colorectal cancer and other malignancies. PMID: 19793002 |
Ref: Antiproliferative effect of chitosan-added kimchi in HT-29 human colon carcinoma cells. PMID: 20136430 Ref: Gamma-tocotrienol promotes TRAIL-induced apoptosis through reactive oxygen species/extracellular signal-regulated kinase/p53-mediated upregulation of death receptors. PMID: 20682650 |
Ref: Nuclear factor kappa-light chain-enhancer of activated B cells is activated by radiotherapy and is prognostic for overall survival in patients with rectal cancer treated with preoperative fluorouracil-based chemoradiotheraphy. PMID: 20630669 Ref: Inhibitor of apoptosis protein family as diagnostic markers and therapeutic targets of colorectal cancer. PMID: 21264751 Ref: Therapeutic potential and molecular mechanism of a novel, potent, nonpeptide, Smac mimetic SM-164 in combination with TRAIL for cancer treatment. PMID: 21372226 Ref: Concomitant activation of caspase-9 and down-regulation of IAP proteins as a mechanism of apoptotic death in HepG2, T47D and HCT-116 cells upon exposure to a derivative from 4-aryl-4H-chromenes family. PMID: 21565459 |
Ref: An apoptosis-independent role of SMAC in tumor suppression. PMID: 22751125 Ref: Gene signature distinguishes patients with chronic ulcerative colitis harboring remote neoplastic lesions. PMID: 23388545 Ref: A personalized preclinical model to evaluate the metastatic potential of patient-derived colon cancer initiating cells. PMID: 24170545 |
Ref: Berberine enhances chemosensitivity to irinotecan in colon cancer via inhibition of NFkappaB. PMID: 24173769 Ref: The LEF1/CYLD axis and cIAPs regulate RIP1 deubiquitination and trigger apoptosis in selenite-treated colorectal cancer cells. PMID: 24577083 Ref: Variable NF-kappaB pathway responses in colon cancer cells treated with chemotherapeutic drugs. PMID: 25134433 Ref: EGFR-targeted TRAIL and a Smac mimetic synergize to overcome apoptosis resistance in KRAS mutant colorectal cancer cells. PMID: 25198428 |
Ref: Usefulness of alternate-day administration of S-1 and leucovorin in a xenograft mouse model of colorectal cancer: a shorter drug-free interval leads to more efficient antitumor effects. PMID: 24802097 Ref: High levels of X-linked Inhibitor-of-Apoptosis Protein (XIAP) are indicative of radio chemotherapy resistance in rectal cancer. PMID: 26071313 Ref: The SMAC mimetic BV6 sensitizes colorectal cancer cells to ionizing radiation by interfering with DNA repair processes and enhancing apoptosis. PMID: 26383618 Ref: A-kinase anchor protein 4 (AKAP4) a promising therapeutic target of colorectal cancer. PMID: 26590805 Ref: Microarray Analysis of Gene Expression at the Tumor Front of Colon Cancer. PMID: 26637872 |
Ref: A critical role for cellular inhibitor of protein 2 (cIAP2) in colitis-associated colorectal cancer and intestinal homeostasis mediated by the inflammasome and survival pathways. PMID: 26037070 Ref: Systematic Analysis of Gene Expression Alterations and Clinical Outcomes for Long-Chain Acyl-Coenzyme A Synthetase Family in Cancer. PMID: 27171439 Ref: [Roles of glucose-regulated protein 78 in proliferation and migration of human colorectal carcinoma cell line RKO]. PMID: 27256049 Ref: Death receptor 5 (DR5) and a 5-gene apoptotic biomarker panel with significant differential diagnostic potential in colorectal cancer. PMID: 27827395 |
Ref: Inhibitor of Apoptosis Protein-1 Regulates Tumor Necrosis Factor-Mediated Destruction of Intestinal Epithelial Cells. PMID: 27889570 Ref: Evaluation of the Expression of the Inhibitor of Apoptosis Protein Family and Human Telomerase Reverse Transcriptase in Patients With Advanced Colorectal Adenoma. PMID: 28698863 |
Ref: Toll-like receptor 2 stimulation promotes colorectal cancer cell growth via PI3K/Akt and NF-kappaB signaling pathways. PMID: 29689497 Ref: Transcriptomic analysis reveals the underlying pro-malignant functions of Gankyrin for colorectal cancer via affecting tumor necrosis factor pathway. PMID: 29883699 Ref: Tristetraprolin activation by resveratrol inhibits the proliferation and metastasis of colorectal cancer cells. PMID: 29956753 |