Primary Site >> Colorectal Cancer

Gene >> BIRC2

Journal: Oncogene. 1998 Dec 24;17(25):3247-59.
Title: The inhibitors of apoptosis (IAPs) and their emerging role in cancer.
Author: LaCasse, E C|Baird, S|Korneluk, R G|MacKenzie, A E
PMID: 9916987
Journal: Proc Natl Acad Sci U S A. 2003 Jul 22;100(15):8921-6.
Title: Inhibition of apoptosis in normal and transformed intestinal epithelial cells by cAMP through induction of inhibitor of apoptosis protein (IAP)-2.
Author: Nishihara, Hiroshi|Kizaka-Kondoh, Shinae|Insel, Paul A|Eckmann, Lars
PMID: 12837940
Journal: Pathol Res Pract. 2003;199(11):723-31.
Title: Subcellular expression of c-IAP1 and c-IAP2 in colorectal cancers: relationships with clinicopathological features and prognosis.
Author: Ponnelle, Tibor|Chapusot, Caroline|Martin, Laurent|Bonithon-Kopp, Claire|Bouvier, Anne Marie|Plenchette, Stephanie|Rageot, David|Faivre, Jean|Solary, Eric|Piard, Francoise
PMID: 14708638
Journal: Int J Oncol. 2003 Aug;23(2):503-8.
Title: Sodium salicylate induces apoptosis in HCT116 colorectal cancer cells through activation of p38MAPK.
Author: Lee, Eun Ju|Park, Hye Geong|Kang, Ho Sung
PMID: 12851702
Journal: Cancer Immunol Immunother. 2004 Sep;53(9):770-6. Epub 2004 May 11.
Title: Expression of IAP family proteins in colon cancers from patients with different age groups.
Author: Endo, T|Abe, S|Seidlar, H B K|Nagaoka, S|Takemura, T|Utsuyama, M|Kitagawa, M|Hirokawa, K
PMID: 15138717
Journal: Oncogene. 2004 Oct 7;23(46):7712-21.
Title: Luteolin sensitizes tumor necrosis factor-alpha-induced apoptosis in human tumor cells.
Author: Shi, Ran-Xin|Ong, Choon-Nam|Shen, Han-Ming
PMID: 15334063
Journal: Oncogene. 2005 Mar 17;24(12):2050-8.
Title: Casein kinase II (CK2) enhances death-inducing signaling complex (DISC) activity in TRAIL-induced apoptosis in human colon carcinoma cell lines.
Author: Izeradjene, Kamel|Douglas, Leslie|Delaney, Addison|Houghton, Janet A
PMID: 15688023
Journal: J Pharmacol Sci. 2007 Aug;104(4):374-83.
Title: Inhibition of cell growth and induction of apoptosis via inactivation of NF-kappaB by a sulfurcompound isolated from garlic in human colon cancer cells.
Author: Ban, Jung Ok|Yuk, Dong Yeon|Woo, Koan Sik|Kim, Tae Myoung|Lee, Ung Soo|Jeong, Heon-Sang|Kim, Dae Joong|Chung, Yeun Bok|Hwang, Bang Yeon|Oh, Ki Wan|Hong, Jin Tae
PMID: 17721042
Journal: Oncogene. 2008 Feb 14;27(8):1122-34. Epub 2007 Aug 20.
Title: The apoptosis-inducing effect of gastrin on colorectal cancer cells relates to an increased IEX-1 expression mediating NF-kappa B inhibition.
Author: Sebens Muerkoster, S|Rausch, A V|Isberner, A|Minkenberg, J|Blaszczuk, E|Witt, M|Folsch, U R|Schmitz, F|Schafer, H|Arlt, A
PMID: 17704804
Journal: Mol Endocrinol. 2008 Apr;22(4):868-80. Epub 2007 Dec 20.
Title: The antiapoptotic role of pregnane X receptor in human colon cancer cells.
Author: Zhou, Jie|Liu, Mingjie|Zhai, Yonggong|Xie, Wen
PMID: 18096695
Journal: Cancer Res. 2008 May 1;68(9):3379-88.
Title: Bortezomib (Velcade) induces p27Kip1 expression through S-phase kinase protein 2 degradation in colorectal cancer.
Author: Uddin, Shahab|Ahmed, Maqbool|Bavi, Prashant|El-Sayed, Raafat|Al-Sanea, Nasser|AbdulJabbar, Alaa|Ashari, Luai H|Alhomoud, Samar|Al-Dayel, Fouad|Hussain, Azhar R|Al-Kuraya, Khawla S
PMID: 18451165
Journal: Int J Cancer. 2008 Aug 15;123(4):951-7.
Title: Simvastatin induces apoptosis in human colon cancer cells and in tumor xenografts, and attenuates colitis-associated colon cancer in mice.
Author: Cho, Soo-Jeong|Kim, Joo Sung|Kim, Jung Mogg|Lee, Jong Yeul|Jung, Hyun Chae|Song, In Sung
PMID: 18521906
Journal: Int J Radiat Oncol Biol Phys. 2009 Oct 1;75(2):534-42.
Title: Curcumin modulates the radiosensitivity of colorectal cancer cells by suppressing constitutive and inducible NF-kappaB activity.
Author: Sandur, Santosh K|Deorukhkar, Amit|Pandey, Manoj K|Pabon, Ana Maria|Shentu, Shujun|Guha, Sushovan|Aggarwal, Bharat B|Krishnan, Sunil
PMID: 19735878
Journal: PLoS One. 2010 Jan 21;5(1):e8836.
Title: MicroRNA-145 targets YES and STAT1 in colon cancer cells.
Author: Gregersen, Lea H|Jacobsen, Anders B|Frankel, Lisa B|Wen, Jiayu|Krogh, Anders|Lund, Anders H
PMID: 20098684
Journal: Surgery. 2010 Aug;148(2):346-53.
Title: In vitro and in vivo radiosensitization of colorectal cancer HT-29 cells by the smac mimetic JP-1201.
Author: Huerta, Sergio|Gao, Xiaohuan|Livingston, Edward H|Kapur, Payal|Sun, Haizhou|Anthony, Thomas
PMID: 20633731
Journal: Surg Today. 2011 Feb;41(2):175-82.
Title: Inhibitor of apoptosis protein family as diagnostic markers and therapeutic targets of colorectal cancer.
Author: Miura, Koh|Fujibuchi, Wataru|Ishida, Kazuyuki|Naitoh, Takeshi|Ogawa, Hitoshi|Ando, Toshinori|Yazaki, Nobuki|Watanabe, Kazuhiro|Haneda, Sho|Shibata, Chikashi|Sasaki, Iwao
PMID: 21264751
Journal: Mol Cancer Ther. 2011 May;10(5):902-14.
Title: Therapeutic potential and molecular mechanism of a novel, potent, nonpeptide, Smac mimetic SM-164 in combination with TRAIL for cancer treatment.
Author: Lu, Jianfeng|McEachern, Donna|Sun, Haiying|Bai, Longchuan|Peng, Yuefeng|Qiu, Su|Miller, Rebecca|Liao, Jinhui|Yi, Han|Liu, Meilan|Bellail, Anita|Hao, Chunhai|Sun, Shi-Yong|Ting, Adrian T|Wang, Shaomeng
PMID: 21372226
Journal: Oncogene. 2013 May 9;32(19):2380-9.
Title: An apoptosis-independent role of SMAC in tumor suppression.
Author: Qiu, W|Liu, H|Sebastini, A|Sun, Q|Wang, H|Zhang, L|Yu, J
PMID: 22751125
Journal: Pathol Oncol Res. 2014 Apr;20(2):301-7.
Title: Down-regulation of BAX gene during carcinogenesis and acquisition of resistance to 5-FU in colorectal cancer.
Author: Manoochehri, Mehdi|Karbasi, Ashraf|Bandehpour, Mojgan|Kazemi, Bahram
PMID: 24122668
Journal: Mol Med Rep. 2014 Jan;9(1):249-54.
Title: Berberine enhances chemosensitivity to irinotecan in colon cancer via inhibition of NFkappaB.
Author: Yu, Meiling|Tong, Xuhui|Qi, Benquan|Qu, Hongdang|Dong, Shuying|Yu, Binbin|Zhang, Naiju|Tang, Nan|Wang, Lingzhi|Zhang, Cuiling
PMID: 24173769
Journal: BMC Cancer. 2014 Jan 15;14:24.
Title: Ceramide targets xIAP and cIAP1 to sensitize metastatic colon and breast cancer cells to apoptosis induction to suppress tumor progression.
Author: Paschall, Amy V|Zimmerman, Mary A|Torres, Christina M|Yang, Dafeng|Chen, May R|Li, Xia|Bieberich, Erhard|Bai, Aiping|Bielawski, Jacek|Bielawska, Alicja|Liu, Kebin
PMID: 24422988
Journal: Cancers (Basel). 2014 Jan 21;6(1):166-78.
Title: Gene Expression Profiling Identifies Important Genes Affected by R2 Compound Disrupting FAK and P53 Complex.
Author: Golubovskaya, Vita M|Ho, Baotran|Conroy, Jeffrey|Liu, Song|Wang, Dan|Cance, William G
PMID: 24452144
Journal: Cell Death Dis. 2014 Feb 27;5:e1085.
Title: The LEF1/CYLD axis and cIAPs regulate RIP1 deubiquitination and trigger apoptosis in selenite-treated colorectal cancer cells.
Author: Wu, P|Shi, K J|An, J J|Ci, Y L|Li, F|Hui, K Y|Yang, Y|Xu, C M
PMID: 24577083
Journal: Biochim Biophys Acta. 2014 Sep;1841(9):1308-17.
Title: DHA-mediated enhancement of TRAIL-induced apoptosis in colon cancer cells is associated with engagement of mitochondria and specific alterations in sphingolipid metabolism.
Author: Skender, Belma|Hofmanova, Jirina|Slavik, Josef|Jelinkova, Iva|Machala, Miroslav|Moyer, Mary Pat|Kozubik, Alois|Hyrslova Vaculova, Alena
PMID: 24953781
Journal: Cell Death Differ. 2015 Sep;22(9):1463-76.
Title: USP11-dependent selective cIAP2 deubiquitylation and stabilization determine sensitivity to Smac mimetics.
Author: Lee, E-W|Seong, D|Seo, J|Jeong, M|Lee, H-K|Song, J
PMID: 25613375
Journal: Tumour Biol. 2015 Sep;36(10):8107-20.
Title: Cellular prion protein contributes to LS 174T colon cancer cell carcinogenesis by increasing invasiveness and resistance against doxorubicin-induced apoptosis.
Author: Chieng, Cornelius Kwang-Lee|Say, Yee-How
PMID: 25983001
Journal: Mol Cancer Ther. 2015 Nov;14(11):2569-75.
Title: A Phase I Study of the SMAC-Mimetic Birinapant in Adults with Refractory Solid Tumors or Lymphoma.
Author: Amaravadi, Ravi K|Schilder, Russell J|Martin, Lainie P|Levin, Myron|Graham, Martin A|Weng, David E|Adjei, Alex A
PMID: 26333381
Journal: Radiat Oncol. 2015 Sep 17;10:198.
Title: The SMAC mimetic BV6 sensitizes colorectal cancer cells to ionizing radiation by interfering with DNA repair processes and enhancing apoptosis.
Author: Hehlgans, Stephanie|Oppermann, Julius|Reichert, Sebastian|Fulda, Simone|Rodel, Claus|Rodel, Franz
PMID: 26383618
Journal: Colloids Surf B Biointerfaces. 2016 Aug 1;144:1-7.
Title: Colloidal mesoporous silica nanoparticles enhance the biological activity of resveratrol.
Author: Summerlin, Natalie|Qu, Zhi|Pujara, Naisarg|Sheng, Yong|Jambhrunkar, Siddharth|McGuckin, Michael|Popat, Amirali
PMID: 27060664
Journal: Sci Rep. 2016 Nov 9;6:36532.
Title: Death receptor 5 (DR5) and a 5-gene apoptotic biomarker panel with significant differential diagnostic potential in colorectal cancer.
Author: Devetzi, Marina|Kosmidou, Vivian|Vlassi, Margarita|Perysinakis, Iraklis|Aggeli, Chrysanthi|Choreftaki, Theodosia|Zografos, Georgios N|Pintzas, Alexander
PMID: 27827395
Journal: Oncogene. 2017 Feb 2;36(5):700-713.
Title: MUC13 protects colorectal cancer cells from death by activating the NF-kappaB pathway and is a potential therapeutic target.
Author: Sheng, Y H|He, Y|Hasnain, S Z|Wang, R|Tong, H|Clarke, D T|Lourie, R|Oancea, I|Wong, K Y|Lumley, J W|Florin, T H|Sutton, P|Hooper, J D|McMillan, N A|McGuckin, M A
PMID: 27399336
Journal: Gastroenterology. 2017 Mar;152(4):867-879.
Title: Inhibitor of Apoptosis Protein-1 Regulates Tumor Necrosis Factor-Mediated Destruction of Intestinal Epithelial Cells.
Author: Grabinger, Thomas|Bode, Konstantin J|Demgenski, Janine|Seitz, Carina|Delgado, M Eugenia|Kostadinova, Feodora|Reinhold, Cindy|Etemadi, Nima|Wilhelm, Sabine|Schweinlin, Matthias|Hanggi, Kay|Knop, Janin|Hauck, Christof|Walles, Heike|Silke, John|Wajant, Haral
PMID: 27889570
Journal: J Cancer Prev. 2017 Jun;22(2):98-102.
Title: Evaluation of the Expression of the Inhibitor of Apoptosis Protein Family and Human Telomerase Reverse Transcriptase in Patients With Advanced Colorectal Adenoma.
Author: Choi, Joon Young|Yoon, Hyuk|Na, Gyeongjae|Choi, Yoon Jin|Shin, Cheol Min|Park, Young Soo|Kim, Nayoung|Lee, Dong Ho
PMID: 28698863
Journal: Carcinogenesis. 2018 Sep 11. pii: 5094840.
Title: Matricellular protein periostin promotes colitis-associated colon tumorigenesis in mice.
Author: Koh, Seong-Joon|Kim, Ji Won|Kim, Byeong Gwan|Lee, Kook Lae|Kim, Dae Woo|Kim, Joo Sung
PMID: 30204842