Primary Site >> Colorectal Cancer
Gene >> BIRC2
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Ref: The inhibitors of apoptosis (IAPs) and their emerging role in cancer. PMID: 9916987 |
Ref: Inhibition of apoptosis in normal and transformed intestinal epithelial cells by cAMP through induction of inhibitor of apoptosis protein (IAP)-2. PMID: 12837940 Ref: Sodium salicylate induces apoptosis in HCT116 colorectal cancer cells through activation of p38MAPK. PMID: 12851702 Ref: Subcellular expression of c-IAP1 and c-IAP2 in colorectal cancers: relationships with clinicopathological features and prognosis. PMID: 14708638 |
Ref: Expression of IAP family proteins in colon cancers from patients with different age groups. PMID: 15138717 Ref: Luteolin sensitizes tumor necrosis factor-alpha-induced apoptosis in human tumor cells. PMID: 15334063 |
Ref: Casein kinase II (CK2) enhances death-inducing signaling complex (DISC) activity in TRAIL-induced apoptosis in human colon carcinoma cell lines. PMID: 15688023 |
Ref: Inhibition of cell growth and induction of apoptosis via inactivation of NF-kappaB by a sulfurcompound isolated from garlic in human colon cancer cells. PMID: 17721042 |
Ref: The apoptosis-inducing effect of gastrin on colorectal cancer cells relates to an increased IEX-1 expression mediating NF-kappa B inhibition. PMID: 17704804 Ref: The antiapoptotic role of pregnane X receptor in human colon cancer cells. PMID: 18096695 Ref: Bortezomib (Velcade) induces p27Kip1 expression through S-phase kinase protein 2 degradation in colorectal cancer. PMID: 18451165 Ref: Simvastatin induces apoptosis in human colon cancer cells and in tumor xenografts, and attenuates colitis-associated colon cancer in mice. PMID: 18521906 |
Ref: Curcumin modulates the radiosensitivity of colorectal cancer cells by suppressing constitutive and inducible NF-kappaB activity. PMID: 19735878 |
Ref: MicroRNA-145 targets YES and STAT1 in colon cancer cells. PMID: 20098684 Ref: In vitro and in vivo radiosensitization of colorectal cancer HT-29 cells by the smac mimetic JP-1201. PMID: 20633731 |
Ref: Inhibitor of apoptosis protein family as diagnostic markers and therapeutic targets of colorectal cancer. PMID: 21264751 Ref: Therapeutic potential and molecular mechanism of a novel, potent, nonpeptide, Smac mimetic SM-164 in combination with TRAIL for cancer treatment. PMID: 21372226 |
Ref: An apoptosis-independent role of SMAC in tumor suppression. PMID: 22751125 |
Ref: Down-regulation of BAX gene during carcinogenesis and acquisition of resistance to 5-FU in colorectal cancer. PMID: 24122668 Ref: Berberine enhances chemosensitivity to irinotecan in colon cancer via inhibition of NFkappaB. PMID: 24173769 Ref: Ceramide targets xIAP and cIAP1 to sensitize metastatic colon and breast cancer cells to apoptosis induction to suppress tumor progression. PMID: 24422988 Ref: Gene Expression Profiling Identifies Important Genes Affected by R2 Compound Disrupting FAK and P53 Complex. PMID: 24452144 Ref: The LEF1/CYLD axis and cIAPs regulate RIP1 deubiquitination and trigger apoptosis in selenite-treated colorectal cancer cells. PMID: 24577083 Ref: DHA-mediated enhancement of TRAIL-induced apoptosis in colon cancer cells is associated with engagement of mitochondria and specific alterations in sphingolipid metabolism. PMID: 24953781 |
Ref: USP11-dependent selective cIAP2 deubiquitylation and stabilization determine sensitivity to Smac mimetics. PMID: 25613375 Ref: Cellular prion protein contributes to LS 174T colon cancer cell carcinogenesis by increasing invasiveness and resistance against doxorubicin-induced apoptosis. PMID: 25983001 Ref: A Phase I Study of the SMAC-Mimetic Birinapant in Adults with Refractory Solid Tumors or Lymphoma. PMID: 26333381 Ref: The SMAC mimetic BV6 sensitizes colorectal cancer cells to ionizing radiation by interfering with DNA repair processes and enhancing apoptosis. PMID: 26383618 |
Ref: Colloidal mesoporous silica nanoparticles enhance the biological activity of resveratrol. PMID: 27060664 Ref: Death receptor 5 (DR5) and a 5-gene apoptotic biomarker panel with significant differential diagnostic potential in colorectal cancer. PMID: 27827395 |
Ref: MUC13 protects colorectal cancer cells from death by activating the NF-kappaB pathway and is a potential therapeutic target. PMID: 27399336 Ref: Inhibitor of Apoptosis Protein-1 Regulates Tumor Necrosis Factor-Mediated Destruction of Intestinal Epithelial Cells. PMID: 27889570 Ref: Evaluation of the Expression of the Inhibitor of Apoptosis Protein Family and Human Telomerase Reverse Transcriptase in Patients With Advanced Colorectal Adenoma. PMID: 28698863 |
Ref: Matricellular protein periostin promotes colitis-associated colon tumorigenesis in mice. PMID: 30204842 |