Literatures

Primary Site >> Colorectal Cancer

Gene >> BID

1.
Journal:	Oncology (Williston Park). 1998 Oct;12(10 Suppl 7):52-6.
Title:	Clinical development of eniluracil: current status.
Author:	Hohneker, J A
PMID:	9830627

2.
Journal:	J Clin Oncol. 2000 Mar;18(6):1337-45.
Title:	Capecitabine, an oral fluoropyrimidine carbamate with substantial activity in advanced colorectal cancer: results of a randomized phase II study.
Author:	Van Cutsem, E\|Findlay, M\|Osterwalder, B\|Kocha, W\|Dalley, D\|Pazdur, R\|Cassidy, J\|Dirix, L\|Twelves, C\|Allman, D\|Seitz, J F\|Scholmerich, J\|Burger, H U\|Verweij, J
PMID:	10715306

3.
Journal:	Cancer Res. 2001 Feb 15;61(4):1645-51.
Title:	Anticancer agents sensitize tumor cells to tumor necrosis factor-related apoptosis-inducing ligand-mediated caspase-8 activation and apoptosis.
Author:	Lacour, S\|Hammann, A\|Wotawa, A\|Corcos, L\|Solary, E\|Dimanche-Boitrel, M T
PMID:	11245478

4.
Journal:	Oncogene. 2001 Jul 5;20(30):4070-84.
Title:	Mechanism of colon cancer cell apoptosis mediated by pyropheophorbide-a methylester photosensitization.
Author:	Matroule, J Y\|Carthy, C M\|Granville, D J\|Jolois, O\|Hunt, D W\|Piette, J
PMID:	11494135

5.
Journal:	Cancer Res. 2002 Mar 15;62(6):1583-7.
Title:	Requirement of BAX for TRAIL/Apo2L-induced apoptosis of colorectal cancers: synergism with sulindac-mediated inhibition of Bcl-x(L).
Author:	Ravi, Rajani\|Bedi, Atul
PMID:	11912124

6.
Journal:	J Clin Oncol. 2002 Apr 1;20(7):1759-66.
Title:	Phase II study of capecitabine and oxaliplatin in first- and second-line treatment of advanced or metastatic colorectal cancer.
Author:	Borner, Markus M\|Dietrich, Daniel\|Stupp, Roger\|Morant, Rudolf\|Honegger, Hanspeter\|Wernli, Martin\|Herrmann, Richard\|Pestalozzi, Bernhard C\|Saletti, Piercarlo\|Hanselmann, Silvia\|Muller, Samuel\|Brauchli, Peter\|Castiglione-Gertsch, Monica\|Goldhirsch, Aron\|Rot
PMID:	11919232

7.
Journal:	Oncogene. 2002 Sep 5;21(39):6032-40.
Title:	Apo2L/TRAIL differentially modulates the apoptotic effects of sulindac and a COX-2 selective non-steroidal anti-inflammatory agent in Bax-deficient cells.
Author:	He, Qin\|Luo, Xiuquan\|Huang, Ying\|Sheikh, M Saeed
PMID:	12203115

8.
Journal:	J Clin Oncol. 2002 Oct 1;20(19):3983-91.
Title:	Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer.
Author:	Dunst, Jurgen\|Reese, Thomas\|Sutter, Thomas\|Zuhlke, Helmut\|Hinke, Axel\|Kolling-Schlebusch, Katrin\|Frings, Stefan
PMID:	12351595

9.
Journal:	Neoplasia. 2002 Nov-Dec;4(6):551-7.
Title:	Defining characteristics of Types I and II apoptotic cells in response to TRAIL.
Author:	Ozoren, Nesrin\|El-Deiry, Wafik S
PMID:	12407450

10.
Journal:	Biochem J. 2003 Apr 1;371(Pt 1):115-24.
Title:	The anti-apoptotic effect of leukotriene D4 involves the prevention of caspase 8 activation and Bid cleavage.
Author:	Wikstrom, Katarina\|Juhas, Maria\|Sjolander, Anita
PMID:	12482325

11.
Journal:	Cancer Res. 2003 Mar 15;63(6):1254-61.
Title:	Caspase-8 and apoptosis-inducing factor mediate a cytochrome c-independent pathway of apoptosis in human colon cancer cells induced by the dietary phytochemical chlorophyllin.
Author:	Diaz, G Dario\|Li, Qingjie\|Dashwood, Roderick H
PMID:	12649185

12.
Journal:	Oncogene. 2003 Mar 27;22(12):1807-16.
Title:	Chemotherapy enhances TNF-related apoptosis-inducing ligand DISC assembly in HT29 human colon cancer cells.
Author:	Lacour, Sandrine\|Micheau, Olivier\|Hammann, Arlette\|Drouineaud, Veronique\|Tschopp, Jurg\|Solary, Eric\|Dimanche-Boitrel, Marie-Therese
PMID:	12660816

13.
Journal:	Cancer Res. 2003 Apr 1;63(7):1483-9.
Title:	Bax plays a pivotal role in thapsigargin-induced apoptosis of human colon cancer HCT116 cells by controlling Smac/Diablo and Omi/HtrA2 release from mitochondria.
Author:	Yamaguchi, Hirohito\|Bhalla, Kapil\|Wang, Hong-Gang
PMID:	12670894

14.
Journal:	Oncogene. 2003 May 1;22(17):2674-9.
Title:	Effect of Bax deficiency on death receptor 5 and mitochondrial pathways during endoplasmic reticulum calcium pool depletion-induced apoptosis.
Author:	He, Qin\|Montalbano, JoAnne\|Corcoran, Chad\|Jin, Weixin\|Huang, Ying\|Sheikh, M Saeed
PMID:	12730681

15.
Journal:	Oncogene. 2003 Aug 7;22(32):4953-63.
Title:	The proteasome inhibitor PS-341 overcomes TRAIL resistance in Bax and caspase 9-negative or Bcl-xL overexpressing cells.
Author:	Johnson, Thomas R\|Stone, Kimberley\|Nikrad, Malti\|Yeh, Tammie\|Zong, Wei-Xing\|Thompson, Craig B\|Nesterov, Alexandre\|Kraft, Andrew S
PMID:	12902978

16.
Journal:	Exp Cell Res. 2004 Feb 1;293(1):129-43.
Title:	Low extracellular pH augments TRAIL-induced apoptotic death through the mitochondria-mediated caspase signal transduction pathway.
Author:	Lee, Yong J\|Song, Jae J\|Kim, Jin H\|Kim, Hyeong-Reh Choi\|Song, Young K
PMID:	14729063

17.
Journal:	Mol Cell Biol. 2004 Apr;24(7):2875-89.
Title:	Hypoxia-mediated down-regulation of Bid and Bax in tumors occurs via hypoxia-inducible factor 1-dependent and -independent mechanisms and contributes to drug resistance.
Author:	Erler, Janine T\|Cawthorne, Christopher J\|Williams, Kaye J\|Koritzinsky, Marianne\|Wouters, Bradley G\|Wilson, Clare\|Miller, Crispin\|Demonacos, Costas\|Stratford, Ian J\|Dive, Caroline
PMID:	15024076

18.
Journal:	J Biol Chem. 2004 Aug 20;279(34):35829-39. Epub 2004 May 20.
Title:	Deficient tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) death receptor transport to the cell surface in human colon cancer cells selected for resistance to TRAIL-induced apoptosis.
Author:	Jin, Zhaoyu\|McDonald, E Robert 3rd\|Dicker, David T\|El-Deiry, Wafik S
PMID:	15155747

19.
Journal:	Cancer Lett. 2004 Aug 10;211(2):175-88.
Title:	Involvement of proapoptotic Bcl-2 family members in parthenolide-induced mitochondrial dysfunction and apoptosis.
Author:	Zhang, Siyuan\|Ong, Choon-Nam\|Shen, Han-Ming
PMID:	15219941

20.
Journal:	Clin Cancer Res. 2004 Jul 1;10(13):4374-82.
Title:	A phase I clinical and pharmacokinetic study of Ro 31-7453 given as a 7- or 14-day oral twice daily schedule every 4 weeks in patients with solid tumors.
Author:	Salazar, Ramon\|Bissett, Donald\|Twelves, Chris\|Breimer, Lars\|DeMario, Mark\|Campbell, Sophia\|Zhi, Jay\|Ritland, Steve\|Cassidy, Jim
PMID:	15240525

21.
Journal:	World J Gastroenterol. 2004 Aug 1;10(15):2205-8.
Title:	Honokiol induces apoptosis through p53-independent pathway in human colorectal cell line RKO.
Author:	Wang, Tao\|Chen, Fei\|Chen, Zhe\|Wu, Yi-Feng\|Xu, Xiao-Li\|Zheng, Shu\|Hu, Xun
PMID:	15259066

22.
Journal:	Cancer Lett. 2004 Sep 15;213(1):21-9.
Title:	Lactoferrin modifies apoptosis-related gene expression in the colon of the azoxymethane-treated rat.
Author:	Fujita, Ken-ichi\|Matsuda, Eiji\|Sekine, Kazunori\|Iigo, Masaaki\|Tsuda, Hiroyuki
PMID:	15312680

23.
Journal:	FEBS Lett. 2004 Nov 5;577(1-2):309-13.
Title:	Ethanol acts as a potent agent sensitizing colon cancer cells to the TRAIL-induced apoptosis.
Author:	Vaculova, Alena\|Hofmanova, Jirina\|Soucek, Karel\|Andera, Ladislav\|Kozubik, Alois
PMID:	15527805

24.
Journal:	Clin Cancer Res. 2004 Dec 15;10(24):8284-92.
Title:	Tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis is inhibited by Bcl-2 but restored by the small molecule Bcl-2 inhibitor, HA 14-1, in human colon cancer cells.
Author:	Sinicrope, Frank A\|Penington, Robert C\|Tang, Xi Ming
PMID:	15623604

25.
Journal:	Arch Pharm Res. 2004 Dec;27(12):1253-7.
Title:	Apoptosis inducing effects of 6-methoxydihydrosanguinarine in HT29 colon carcinoma cells.
Author:	Lee, Yong-Jin\|Yin, Hu-Quan\|Kim, Young-Ho\|Li, Guang-Yong\|Lee, Byung-Hoon
PMID:	15646800

26.
Journal:	Oncogene. 2005 Feb 17;24(8):1338-47.
Title:	Caveolin-1 inhibits cell detachment-induced p53 activation and anoikis by upregulation of insulin-like growth factor-I receptors and signaling.
Author:	Ravid, Dana\|Maor, Sharon\|Werner, Haim\|Liscovitch, Mordechai
PMID:	15592498

27.
Journal:	Oncogene. 2005 Mar 17;24(12):2050-8.
Title:	Casein kinase II (CK2) enhances death-inducing signaling complex (DISC) activity in TRAIL-induced apoptosis in human colon carcinoma cell lines.
Author:	Izeradjene, Kamel\|Douglas, Leslie\|Delaney, Addison\|Houghton, Janet A
PMID:	15688023

28.
Journal:	Prostaglandins Other Lipid Mediat. 2005 Jan;75(1-4):169-72.
Title:	A phase I study of 5-fluorouracil, leucovorin, and celecoxib in patients with incurable colorectal cancer.
Author:	Blanke, Charles D\|Mattek, Nora C\|Deloughery, Thomas G\|Koop, Dennis R
PMID:	15789623

29.
Journal:	Br J Cancer. 2005 Apr 25;92(8):1430-41.
Title:	HGS-ETR1, a fully human TRAIL-receptor 1 monoclonal antibody, induces cell death in multiple tumour types in vitro and in vivo.
Author:	Pukac, L\|Kanakaraj, P\|Humphreys, R\|Alderson, R\|Bloom, M\|Sung, C\|Riccobene, T\|Johnson, R\|Fiscella, M\|Mahoney, A\|Carrell, J\|Boyd, E\|Yao, X T\|Zhang, L\|Zhong, L\|von Kerczek, A\|Shepard, L\|Vaughan, T\|Edwards, B\|Dobson, C\|Salcedo, T\|Albert, V
PMID:	15846298

30.
Journal:	Cancer Chemother Pharmacol. 2005 Nov;56(5):481-6.
Title:	Biweekly oxaliplatin combined with oral capecitabine (OXXEL regimen) as first-line treatment of metastatic colorectal cancer patients: a Southern Italy Cooperative Oncology Group phase II study.
Author:	Comella, P\|Massidda, B\|Palmeri, S\|Farris, A\|Lucia, L De\|Natale, D\|Maiorino, L\|Tafuto, S\|Cataldis, G De\|Casaretti, R
PMID:	15902461

31.
Journal:	World J Gastroenterol. 2005 May 28;11(20):3040-5.
Title:	Molecular mechanisms of denbinobin-induced anti-tumorigenesis effect in colon cancer cells.
Author:	Yang, Kuo-Ching\|Uen, Yih-Huei\|Suk, Fat-Moon\|Liang, Yu-Chih\|Wang, Ying-Jan\|Ho, Yuan-Soon\|Li, I-Hsuan\|Lin, Shyr-Yi
PMID:	15918186

32.
Journal:	Cancer Cell Int. 2005 Jun 1;5(1):18.
Title:	Preclinical evaluation of the proteasome inhibitor bortezomib in cancer therapy.
Author:	Boccadoro, Mario\|Morgan, Gareth\|Cavenagh, Jamie
PMID:	15929791

33.
Journal:	Cancer Biol Ther. 2005 Jul;4(7):781-6. Epub 2005 Jul 6.
Title:	Proteasome inhibitors-mediated TRAIL resensitization and Bik accumulation.
Author:	Zhu, Hongbo\|Guo, Wei\|Zhang, Lidong\|Wu, Shuhong\|Teraishi, Fuminori\|Davis, John J\|Dong, Fengqin\|Fang, Bingliang
PMID:	16082182

34.
Journal:	J Biochem. 2005 Aug;138(2):151-7.
Title:	Characteristics of apoptosis in HCT116 colon cancer cells induced by deoxycholic acid.
Author:	Yui, Satoko\|Saeki, Tohru\|Kanamoto, Ryuhei\|Iwami, Kimikazu
PMID:	16091589

35.
Journal:	Cancer Lett. 2005 Nov 8;229(1):43-8. Epub 2005 Jan 18.
Title:	TRAIL and docosahexaenoic acid cooperate to induce HT-29 colon cancer cell death.
Author:	Vaculova, Alena\|Hofmanova, Jirina\|Andera, Ladislav\|Kozubik, Alois
PMID:	16157217

36.
Journal:	J Clin Oncol. 2005 Dec 1;23(34):8739-47.
Title:	Phase II trial of high-dose conformal radiation therapy with concurrent hepatic artery floxuridine for unresectable intrahepatic malignancies.
Author:	Ben-Josef, Edgar\|Normolle, Daniel\|Ensminger, William D\|Walker, Suzette\|Tatro, Daniel\|Ten Haken, Randall K\|Knol, James\|Dawson, Laura A\|Pan, Charlie\|Lawrence, Theodore S
PMID:	16314634

37.
Journal:	J Biol Chem. 2006 Jun 30;281(26):17599-611. Epub 2006 Apr 14.
Title:	Caspase-2 triggers Bax-Bak-dependent and -independent cell death in colon cancer cells treated with resveratrol.
Author:	Mohan, John\|Gandhi, Alankaram Arul\|Bhavya, Balan Chandrika\|Rashmi, Ramachandran\|Karunagaran, Devarajan\|Indu, Ramachandran\|Santhoshkumar, Thankayyan Ratnabhai
PMID:	16617056

38.
Journal:	Anticancer Res. 2006 Jul-Aug;26(4B):3033-41.
Title:	Antiangiogenic effect of sulindac sulfide could be secondary to induction of apoptosis and cell cycle arrest.
Author:	Flis, S\|Soltysiak-Pawluczuk, D\|Jedrych, A\|Jastrzebski, Z\|Remiszewska, M\|Splawinski, J
PMID:	16886631

39.
Journal:	Cancer Biol Ther. 2006 Nov;5(11):1511-20. Epub 2006 Nov 19.
Title:	Photochemically mediated delivery of AdhCMV-TRAIL augments the TRAIL-induced apoptosis in colorectal cancer cell lines.
Author:	Engesaeter, Birgit O\|Bonsted, Anette\|Lillehammer, Trine\|Engebraaten, Olav\|Berg, Kristian\|Maelandsmo, Gunhild M
PMID:	17012835

40.
Journal:	Wei Sheng Yan Jiu. 2006 Sep;35(5):537-40.
Title:	[Effect of ceramide on apoptosis of human colon cancer HT-29 cells].
Author:	Zhang, Xiao-Feng\|Li, Bai-Xiang\|Ren, Rui
PMID:	17086696

41.
Journal:	J Nutr. 2007 Jan;137(1):31-6.
Title:	Activation of caspase-8 contributes to 3,3'-Diindolylmethane-induced apoptosis in colon cancer cells.
Author:	Kim, Eun Ji\|Park, So Young\|Shin, Hyun-Kyung\|Kwon, Dae Young\|Surh, Young-Joon\|Park, Jung Han Yoon
PMID:	17182797

42.
Journal:	Int J Oncol. 2007 Mar;30(3):679-87.
Title:	Fenretinide up-regulates DR5/TRAIL-R2 expression via the induction of the transcription factor CHOP and combined treatment with fenretinide and TRAIL induces synergistic apoptosis in colon cancer cell lines.
Author:	Kouhara, Junji\|Yoshida, Tatsushi\|Nakata, Susumu\|Horinaka, Mano\|Wakada, Miki\|Ueda, Yuji\|Yamagishi, Hisakazu\|Sakai, Toshiyuki
PMID:	17273769

43.
Journal:	Apoptosis. 2007 Jul;12(7):1299-315.
Title:	Bid is cleaved upstream of caspase-8 activation during TRAIL-mediated apoptosis in human osteosarcoma cells.
Author:	Garnett, Theodore O\|Filippova, Maria\|Duerksen-Hughes, Penelope Jayne
PMID:	17431792

44.
Journal:	In Vivo. 2007 Mar-Apr;21(2):381-7.
Title:	4- [3,5-bis(trimethylsilyl)benzamido] benzoic acid (TAC-101) induced fas expression and activated caspase-3 and -8 in a DLD-1 colon cancer cell line.
Author:	Inoue, Yuzuru\|Nakayama, Yoshifumi\|Sako, Tatsuhiko\|Minagawa, Noritaka\|Abe, Yukio\|Nagato, Masaru\|Kadowaki, Koji\|Katsuki, Takefumi\|Matsumoto, Kentaro\|Tsurudome, Yosuke\|Shibao, Kazunori\|Hirata, Keiji\|Nagata, Naoki
PMID:	17436592

45.
Journal:	Mol Cancer Ther. 2007 May;6(5):1562-71.
Title:	5-Aminoimidazole-4-carboxamide riboside sensitizes TRAIL- and TNF{alpha}-induced cytotoxicity in colon cancer cells through AMP-activated protein kinase signaling.
Author:	Su, Rong-Ying\|Chao, Yee\|Chen, Tsai-Yu\|Huang, Duen-Yi\|Lin, Wan-Wan
PMID:	17513605

46.
Journal:	Mol Pharmacol. 2007 Sep;72(3):704-14. Epub 2007 Jun 19.
Title:	Low-dose BBR3610 toxicity in colon cancer cells is p53-independent and enhanced by inhibition of epidermal growth factor receptor (ERBB1)-phosphatidyl inositol 3 kinase signaling.
Author:	Mitchell, Clint\|Kabolizadeh, Peyman\|Ryan, John\|Roberts, John D\|Yacoub, Adly\|Curiel, David T\|Fisher, Paul B\|Hagan, Michael P\|Farrell, Nicholas P\|Grant, Steven\|Dent, Paul
PMID:	17578896

47.
Journal:	J Surg Res. 2007 Sep;142(1):184-94. Epub 2007 Jul 2.
Title:	Modification of gene products involved in resistance to apoptosis in metastatic colon cancer cells: roles of Fas, Apaf-1, NFkappaB, IAPs, Smac/DIABLO, and AIF.
Author:	Huerta, Sergio\|Heinzerling, John H\|Anguiano-Hernandez, Yu-Mei\|Huerta-Yepez, Sara\|Lin, Jeffrey\|Chen, David\|Bonavida, Benjamin\|Livingston, Edward H
PMID:	17603079

48.
Journal:	Cancer Sci. 2007 Sep;98(9):1417-23.
Title:	Lipoxygenase inhibitors induce death receptor 5/TRAIL-R2 expression and sensitize malignant tumor cells to TRAIL-induced apoptosis.
Author:	Yoshida, Tatsushi\|Shiraishi, Takumi\|Horinaka, Mano\|Nakata, Susumu\|Yasuda, Takashi\|Goda, Ahmed E\|Wakada, Miki\|Mizutani, Yoichi\|Miki, Tsuneharu\|Nishikawa, Akiyoshi\|Sakai, Toshiyuki
PMID:	17645780

49.
Journal:	Arch Toxicol. 2007 Oct;81(10):719-28. Epub 2007 Aug 3.
Title:	Berberine induces apoptosis in SW620 human colonic carcinoma cells through generation of reactive oxygen species and activation of JNK/p38 MAPK and FasL.
Author:	Hsu, Wen-Hsiu\|Hsieh, Yih-Shou\|Kuo, Hsing-Chun\|Teng, Chun-Yuh\|Huang, Hai-I\|Wang, Chau-Jong\|Yang, Shun-Fa\|Liou, Yi-Sheng\|Kuo, Wu-Hsien
PMID:	17673978

50.
Journal:	Mol Cancer Ther. 2007 Sep;6(9):2591-9.
Title:	Quercetin enhances TRAIL-mediated apoptosis in colon cancer cells by inducing the accumulation of death receptors in lipid rafts.
Author:	Psahoulia, Faiy H\|Drosopoulos, Konstantinos G\|Doubravska, Lenka\|Andera, Ladislav\|Pintzas, Alexander
PMID:	17876056

51.
Journal:	J Biol Chem. 2007 Nov 23;282(47):34457-67. Epub 2007 Sep 26.
Title:	A novel interaction between procaspase 8 and SPARC enhances apoptosis and potentiates chemotherapy sensitivity in colorectal cancers.
Author:	Tang, Michelle J\|Tai, Isabella T
PMID:	17897953

52.
Journal:	Clin Pharmacokinet. 2007;46(11):953-63.
Title:	A clinical pharmacokinetic analysis of tegafur-uracil (UFT) plus leucovorin given in a new twice-daily oral administration schedule.
Author:	Etienne-Grimaldi, Marie-Christine\|Francois, Eric\|Cardot, Jean-Michel\|Renee, Nicole\|Douillard, Jean-Yves\|Gamelin, Erick\|Bennouna, Jaafar\|Chateau, Yann\|Milano, Gerard
PMID:	17922560

53.
Journal:	Br J Pharmacol. 2008 Mar;153(5):870-8. Epub 2007 Dec 17.
Title:	Celecoxib decreases expression of the adhesion molecules ICAM-1 and VCAM-1 in a colon cancer cell line (HT29).
Author:	Gallicchio, M\|Rosa, A C\|Dianzani, C\|Brucato, L\|Benetti, E\|Collino, M\|Fantozzi, R
PMID:	18084318

54.
Journal:	Biochem Pharmacol. 2008 May 1;75(9):1729-42.
Title:	Critical role of Bid and Bax in indirubin-3'-monoxime-induced apoptosis in human cancer cells.
Author:	Shi, Jie\|Shen, Han-Ming
PMID:	18377873

55.
Journal:	Br J Cancer. 2008 Apr 22;98(8):1320-6.
Title:	A dose-escalation study of indisulam in combination with capecitabine (Xeloda) in patients with solid tumours.
Author:	Siegel-Lakhai, W S\|Zandvliet, A S\|Huitema, A D R\|Tibben, M M\|Milano, G\|Girre, V\|Dieras, V\|King, A\|Richmond, E\|Wanders, J\|Beijnen, J H\|Schellens, J H M
PMID:	18414469

56.
Journal:	Apoptosis. 2008 Jun;13(6):782-9.
Title:	The bisphosphonate zoledronic acid inhibits the growth of HCT-116 colon carcinoma cells and induces tumor cell apoptosis.
Author:	Sewing, Lilian\|Steinberg, Florian\|Schmidt, Harald\|Goke, Rudiger
PMID:	18437576

57.
Journal:	Oncogene. 2008 Oct 9;27(46):6012-22.
Title:	A mitochondrial block and expression of XIAP lead to resistance to TRAIL-induced apoptosis during progression to metastasis of a colon carcinoma.
Author:	Ndozangue-Touriguine, O\|Sebbagh, M\|Merino, D\|Micheau, O\|Bertoglio, J\|Breard, J
PMID:	18560353

58.
Journal:	Clin Cancer Res. 2008 Jul 1;14(13):4128-33.
Title:	Proapoptotic Bad and Bid protein expression predict survival in stages II and III colon cancers.
Author:	Sinicrope, Frank A\|Rego, Rafaela L\|Foster, Nathan R\|Thibodeau, Stephen N\|Alberts, Steven R\|Windschitl, Harold E\|Sargent, Daniel J
PMID:	18593990

59.
Journal:	Br J Cancer. 2008 Aug 5;99(3):459-63.
Title:	Reciprocal relationship between expression of hypoxia inducible factor 1alpha (HIF-1alpha) and the pro-apoptotic protein bid in ex vivo colorectal cancer.
Author:	Seenath, M M\|Roberts, D\|Cawthorne, C\|Saunders, M P\|Armstrong, G R\|O'Dwyer, S T\|Stratford, I J\|Dive, C\|Renehan, A G
PMID:	18648372

60.
Journal:	Apoptosis. 2008 Oct;13(10):1232-42.
Title:	Lupulone, a hop bitter acid, activates different death pathways involving apoptotic TRAIL-receptors, in human colon tumor cells and in their derived metastatic cells.
Author:	Lamy, Virginie\|Roussi, Stamatiki\|Chaabi, Mehdi\|Gosse, Francine\|Lobstein, Annelise\|Raul, Francis
PMID:	18726190

61.
Journal:	Zhonghua Zhong Liu Za Zhi. 2008 Apr;30(4):245-9.
Title:	[Overcoming acquired resistance to tumor necrosis factor-related apoptosis-inducing ligand by Bcl-XL small interfering RNA in human colon cancer].
Author:	Zhu, Hong-Bo\|Huang, Xue-Feng\|Hu, Jing-Zi\|Zhou, Wei\|Chen, Wei\|Chen, Lin-Lin\|He, Chao
PMID:	18788624

62.
Journal:	Food Chem Toxicol. 2008 Dec;46(12):3753-8.
Title:	Induction of apoptosis in HT-29 colon cancer cells by crude saponin from Platycodi Radix.
Author:	Kim, Jae-Yong\|Park, Kyoung-Wuk\|Moon, Kwang-Deog\|Lee, Mi-Kyung\|Choi, Jina\|Yee, Sung-Tae\|Shim, Ki-Hwan\|Seo, Kwon-Il
PMID:	18955103

63.
Journal:	Invest New Drugs. 2009 Jun;27(3):262-8.
Title:	Phase I trial of neoadjuvant chemoradiotherapy (CRT) with capecitabine and weekly irinotecan followed by laparoscopic total mesorectal excision (LTME) in rectal cancer patients.
Author:	Ugidos, Lisardo\|Delgado, Salvadora\|Conill, Carlos\|Gines, Angels\|Gallego, Rosa\|Ayuso, Juan Ramon\|Miquel, Rosa\|Tosca, Monica\|de Lacy, Antonio\|Castells, Antoni\|Maurel, Joan
PMID:	18923810

64.
Journal:	Chem Biol Interact. 2009 Feb 12;177(3):218-26.
Title:	Mechanism of apoptosis induced by a newly synthesized derivative of macrosphelides with a thiazole side chain.
Author:	Ahmed, Kanwal\|Matsuya, Yuji\|Nemoto, Hideo\|Zaidi, Syed Faisal Haider\|Sugiyama, Toshiro\|Yoshihisa, Yoko\|Shimizu, Tadamichi\|Kondo, Takashi
PMID:	19014919

65.
Journal:	J Biol Chem. 2009 Jan 30;284(5):3354-64.
Title:	Characterization of enantiomeric bile acid-induced apoptosis in colon cancer cell lines.
Author:	Katona, Bryson W\|Anant, Shrikant\|Covey, Douglas F\|Stenson, William F
PMID:	19054763

66.
Journal:	Apoptosis. 2009 Feb;14(2):203-17.
Title:	Sodium butyrate sensitizes human colon adenocarcinoma COLO 205 cells to both intrinsic and TNF-alpha-dependent extrinsic apoptosis.
Author:	Pajak, Beata\|Gajkowska, Barbara\|Orzechowski, Arkadiusz
PMID:	19130237

67.
Journal:	Cancer Chemother Pharmacol. 2009 Oct;64(5):953-60.
Title:	Prostaglandin synthase 2/cyclooxygenase 2 (PTGS2/COX2) 8473T>C polymorphism associated with prognosis for patients with colorectal cancer treated with capecitabine and oxaliplatin.
Author:	Kim, Jong Gwang\|Chae, Yee Soo\|Sohn, Sang Kyun\|Moon, Joon Ho\|Ryoo, Hun Mo\|Bae, Sung Hwa\|Kum, Yoonseop\|Jeon, Seong Woo\|Lim, Kyoung-Hoon\|Kang, Byung-Mo\|Park, In-Ja\|Choi, Gyu Seog\|Jun, Soo-Han
PMID:	19219602

68.
Journal:	Cancer Lett. 2009 Jun 28;279(1):93-100.
Title:	Guggulsterone induces apoptosis in colon cancer cells and inhibits tumor growth in murine colorectal cancer xenografts.
Author:	An, Min Ji\|Cheon, Jae Hee\|Kim, Seung Won\|Kim, Eun Soo\|Kim, Tae Il\|Kim, Won Ho
PMID:	19232820

69.
Journal:	Mol Pharmacol. 2009 Jul;76(1):192-200.
Title:	S-Adenosylmethionine and methylthioadenosine inhibit cellular FLICE inhibitory protein expression and induce apoptosis in colon cancer cells.
Author:	Li, Tony W H\|Zhang, Qingsong\|Oh, Pilsoo\|Xia, Meng\|Chen, Hui\|Bemanian, Sean\|Lastra, Natalie\|Circ, Magda\|Moyer, Mary Pat\|Mato, Jose M\|Aw, Tak Yee\|Lu, Shelly C
PMID:	19372210

70.
Journal:	Biochem Pharmacol. 2009 May 1;77(9):1487-96.
Title:	A rice bran polyphenol, cycloartenyl ferulate, elicits apoptosis in human colorectal adenocarcinoma SW480 and sensitizes metastatic SW620 cells to TRAIL-induced apoptosis.
Author:	Kong, Carrie K L\|Lam, W S\|Chiu, Lawrence C M\|Ooi, Vincent E C\|Sun, Samuel S M\|Wong, Yum-Shing
PMID:	19426686

71.
Journal:	Toxicol Lett. 2009 Jul 24;188(2):142-7.
Title:	Mechanisms of thiosulfinates from Allium tuberosum L.-induced apoptosis in HT-29 human colon cancer cells.
Author:	Lee, Ju-Hye\|Yang, Hee-Sun\|Park, Kyoung-Wuk\|Kim, Jae-Yong\|Lee, Mi-Kyung\|Jeong, Il-Yun\|Shim, Ki-Hwan\|Kim, Young-Sook\|Yamada, Koji\|Seo, Kwon-Il
PMID:	19446247

72.
Journal:	Food Chem Toxicol. 2009 Sep;47(9):2157-62.
Title:	Anti-proliferative effects of Lethariella zahlbruckneri extracts in human HT-29 human colon cancer cells.
Author:	Ren, Mei Rong\|Hur, Jae-Seoun\|Kim, Jae Yong\|Park, Kyoung-Wuk\|Park, Seong-Chan\|Seong, Chi-Nam\|Jeong, Il-Yun\|Byun, Myung-Woo\|Lee, Mi-Kyung\|Seo, Kwon-Il
PMID:	19501127

73.
Journal:	Biotechnol J. 2009 Jul;4(7):1046-54.
Title:	A putative role for human BFK in DNA damage-induced apoptosis.
Author:	Ozoren, Nesrin\|Inohara, Naohiro\|Nunez, Gabriel
PMID:	19557800

74.
Journal:	Cancer Prev Res (Phila). 2009 Aug;2(8):732-42.
Title:	Regulation of colorectal cancer cell apoptosis by the n-3 polyunsaturated fatty acids Docosahexaenoic and Eicosapentaenoic.
Author:	Giros, Anna\|Grzybowski, Mike\|Sohn, Vanessa R\|Pons, Elisenda\|Fernandez-Morales, Jessica\|Xicola, Rosa M\|Sethi, Puja\|Grzybowski, Jessica\|Goel, Ajay\|Boland, C Richard\|Gassull, Miquel A\|Llor, Xavier
PMID:	19638488

75.
Journal:	J Agric Food Chem. 2009 Nov 25;57(22):10573-8.
Title:	Compound K induces apoptosis via CAMK-IV/AMPK pathways in HT-29 colon cancer cells.
Author:	Kim, Do Yeon\|Park, Min Woo\|Yuan, Hai Dan\|Lee, Hyo Jung\|Kim, Sung Hoon\|Chung, Sung Hyun
PMID:	19845353

76.
Journal:	Cancer Lett. 2010 Jan 1;287(1):98-108.
Title:	Nutlin-3 enhances tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis through up-regulation of death receptor 5 (DR5) in human sarcoma HOS cells and human colon cancer HCT116 cells.
Author:	Hori, Takeshi\|Kondo, Takashi\|Kanamori, Masahiko\|Tabuchi, Yoshiaki\|Ogawa, Ryohei\|Zhao, Qing-Li\|Ahmed, Kanwal\|Yasuda, Taketoshi\|Seki, Shoji\|Suzuki, Kayo\|Kimura, Tomoatsu
PMID:	19577358

77.
Journal:	Am J Clin Oncol. 2010 Jun;33(3):242-5.
Title:	A phase I study of capecitabine, irinotecan, celecoxib, and radiation as neoadjuvant therapy of patients with locally advanced rectal cancer.
Author:	Malik, Imtiaz\|Hussein, Farabi\|Bush, David\|Alqaisi, Munther\|Bernal, Pedro\|Byrd, Janet\|Garberoglio, Carlos
PMID:	19806036

78.
Journal:	Apoptosis. 2010 May;15(5):621-30.
Title:	Fish fatty acids alter markers of apoptosis in colorectal adenoma and adenocarcinoma cell lines but fish consumption has no impact on apoptosis-induction ex vivo.
Author:	Habermann, Nina\|Schon, Adrienne\|Lund, Elizabeth K\|Glei, Michael
PMID:	20107900

79.
Journal:	Chem Biol Interact. 2010 May 14;185(3):182-8.
Title:	Role of fatty acid chain length on the induction of apoptosis by newly synthesized catechin derivatives.
Author:	Ahmed, Kanwal\|Wei, Zheng-Li\|Zhao, Qing-Li\|Nakajima, Noriyuki\|Matsunaga, Takayuki\|Ogasawara, Masaru\|Kondo, Takashi
PMID:	20206613

80.
Journal:	Int J Mol Med. 2010 Sep;26(3):341-9.
Title:	Astragalus saponins modulate mTOR and ERK signaling to promote apoptosis through the extrinsic pathway in HT-29 colon cancer cells.
Author:	Auyeung, Kathy Ka-Wai\|Mok, Nga-Lai\|Wong, Ching-Man\|Cho, Chi-Hin\|Ko, Joshua Ka-Shun
PMID:	20664949

81.
Journal:	BMC Gastroenterol. 2010 Aug 22;10:96.
Title:	Fucoidan present in brown algae induces apoptosis of human colon cancer cells.
Author:	Kim, Eun Ji\|Park, So Young\|Lee, Jae-Yong\|Park, Jung Han Yoon
PMID:	20727207

82.
Journal:	Int J Clin Exp Pathol. 2010 Oct 12;3(8):768-74.
Title:	Correlation between Mcl-1 and pAKT protein expression in colorectal cancer.
Author:	Henderson-Jackson, Evita B\|Helm, James\|Ghayouri, Masoumeh\|Hakam, Ardeshir\|Nasir, Aejaz\|Leon, Marino\|Bui, Marilyn\|Yeatman, Timothy\|Coppola, Domenico
PMID:	21151390

83.
Journal:	Oncol Lett. 2010 May;1(3):541-547.
Title:	Aloe-emodin, an anthraquinone, in vitro inhibits proliferation and induces apoptosis in human colon carcinoma cells.
Author:	Lin, Kai-Yuan\|Uen, Yih-Huei
PMID:	22966340

84.
Journal:	Apoptosis. 2011 Feb;16(2):184-97.
Title:	Sequential caspase-2 and caspase-8 activation is essential for saikosaponin a-induced apoptosis of human colon carcinoma cell lines.
Author:	Kim, Byeong Mo\|Hong, Sung Hee
PMID:	21107704

85.
Journal:	Cancer Chemother Pharmacol. 2011 Aug;68(2):547-52.
Title:	Pilot study of PD-0325901 in previously treated patients with advanced melanoma, breast cancer, and colon cancer.
Author:	Boasberg, Peter D\|Redfern, Charles H\|Daniels, Gregory A\|Bodkin, David\|Garrett, Chris R\|Ricart, Alejandro D
PMID:	21516509

86.
Journal:	BMC Cancer. 2011 Apr 27;11:154.
Title:	The natural triterpene maslinic acid induces apoptosis in HT29 colon cancer cells by a JNK-p53-dependent mechanism.
Author:	Reyes-Zurita, Fernando J\|Pachon-Pena, Gisela\|Lizarraga, Daneida\|Rufino-Palomares, Eva E\|Cascante, Marta\|Lupianez, Jose A
PMID:	21524306

87.
Journal:	World J Gastroenterol. 2011 Apr 28;17(16):2086-95.
Title:	Effects of alpha-mangostin on apoptosis induction of human colon cancer.
Author:	Watanapokasin, Ramida\|Jarinthanan, Faongchat\|Nakamura, Yukio\|Sawasjirakij, Nitisak\|Jaratrungtawee, Amornmart\|Suksamrarn, Sunit
PMID:	21547127

88.
Journal:	Toxicol In Vitro. 2011 Oct;25(7):1302-9.
Title:	Sulforaphane induces cytotoxicity and lysosome- and mitochondria-dependent cell death in colon cancer cells with deleted p53.
Author:	Rudolf, Emil\|Cervinka, Miroslav
PMID:	21557998

89.
Journal:	Biosci Biotechnol Biochem. 2011;75(7):1306-11.
Title:	Isoegomaketone induces apoptosis through caspase-dependent and caspase-independent pathways in human DLD1 cells.
Author:	Cho, Byoung Ok\|Jin, Chang Hyun\|Park, Yong Dae\|Ryu, Hyung Won\|Byun, Myung Woo\|Seo, Kwon Il\|Jeong, Il Yun
PMID:	21737934

90.
Journal:	Apoptosis. 2011 Oct;16(10):1042-53.
Title:	Silibinin triggers apoptotic signaling pathways and autophagic survival response in human colon adenocarcinoma cells and their derived metastatic cells.
Author:	Kauntz, Henriette\|Bousserouel, Souad\|Gosse, Francine\|Raul, Francis
PMID:	21779837

91.
Journal:	Cell Biol Int. 2012 Mar 1;36(3):289-96.
Title:	PEG-liposomal oxaliplatin induces apoptosis in human colorectal cancer cells via Fas/FasL and caspase-8.
Author:	Yang, Chuang\|Liu, Hai-Zhong\|Fu, Zhong-Xue
PMID:	21888623

92.
Journal:	J Clin Pharmacol. 2012 May;52(5):656-69.
Title:	Phase I trial of sorafenib in combination with 5-fluorouracil/leucovorin in advanced solid tumors.
Author:	Shacham-Shmueli, Einat\|Geva, Ravit\|Figer, Arie\|Bulocinic, Sarah\|Nalbandyan, Karen\|Shpigel, Shulim\|Atsmon, Jacob\|Brendel, Erich
PMID:	22232731

93.
Journal:	Toxicol In Vitro. 2012 Apr;26(3):414-20.
Title:	A mitochondria-mediated apoptotic pathway induced by deoxynivalenol in human colon cancer cells.
Author:	Ma, Yanna\|Zhang, Aihua\|Shi, Zhiyu\|He, Chenghua\|Ding, Jujing\|Wang, Xichun\|Ma, Jifei\|Zhang, Haibin
PMID:	22269384

94.
Journal:	Cancer Lett. 2012 Nov 1;324(1):98-108.
Title:	Blocking p38/ERK crosstalk affects colorectal cancer growth by inducing apoptosis in vitro and in preclinical mouse models.
Author:	Chiacchiera, Fulvio\|Grossi, Valentina\|Cappellari, Marianna\|Peserico, Alessia\|Simonatto, Marta\|Germani, Aldo\|Russo, Silvana\|Moyer, Mary P\|Resta, Nicoletta\|Murzilli, Stefania\|Simone, Cristiano
PMID:	22579651

95.
Journal:	Biol Pharm Bull. 2012;35(7):1054-63.
Title:	(1S,2S,3E,7E,11E)-3,7,11,15-Cembratetraen-17,2-olide, a cembrenolide diterpene from soft coral Lobophytum sp., inhibits growth and induces apoptosis in human colon cancer cells through reactive oxygen species generation.
Author:	Hong, Ji-Young\|Boo, Hye-Jin\|Kang, Jung-Il\|Kim, Min-Kyoung\|Yoo, Eun-Sook\|Hyun, Jin-Won\|Koh, Young-Sang\|Kim, Gi Young\|Maeng, Young Hee\|Hyun, Chang Lim\|Chang, Weon Young\|Kim, Young Ho\|Kim, Young Ree\|Kang, Hee-Kyoung
PMID:	22791152

96.
Journal:	Int J Mol Sci. 2012;13(7):9184-93.
Title:	Effect of beta,beta-dimethylacrylshikonin on inhibition of human colorectal cancer cell growth in vitro and in vivo.
Author:	Fan, Yingying\|Jin, Shaoju\|He, Jun\|Shao, Zhenjun\|Yan, Jiao\|Feng, Ting\|Li, Hong
PMID:	22942759

97.
Journal:	Clin Cancer Res. 2012 Nov 1;18(21):5934-48.
Title:	Stichoposide C induces apoptosis through the generation of ceramide in leukemia and colorectal cancer cells and shows in vivo antitumor activity.
Author:	Yun, Seong-Hoon\|Park, Eun-Seon\|Shin, Sung-Won\|Na, Yong-Woo\|Han, Jin-Yeong\|Jeong, Jin-Sook\|Shastina, Valeria V\|Stonik, Valentin A\|Park, Joo-In\|Kwak, Jong-Young
PMID:	23132899

98.
Journal:	Radiother Oncol. 2013 May;107(2):184-8.
Title:	Phase I trial of the combination of the Akt inhibitor nelfinavir and chemoradiation for locally advanced rectal cancer.
Author:	Buijsen, Jeroen\|Lammering, Guido\|Jansen, Rob L H\|Beets, Geerard L\|Wals, Jaap\|Sosef, Meindert\|Den Boer, Marien O\|Leijtens, Jeroen\|Riedl, Robert G\|Theys, Jan\|Lambin, Philippe
PMID:	23647753

99.
Journal:	Toxicol Lett. 2013 Jul 4;220(2):157-66.
Title:	Sanguinarine induces apoptosis in human colorectal cancer HCT-116 cells through ROS-mediated Egr-1 activation and mitochondrial dysfunction.
Author:	Han, Min Ho\|Kim, Gi-Young\|Yoo, Young Hyun\|Choi, Yung Hyun
PMID:	23660334

100.
Journal:	Mol Med Rep. 2013 Oct;8(4):1017-22.
Title:	hClock gene expression in human colorectal carcinoma.
Author:	Wang, Liying\|Chen, Bozan\|Wang, Yaping\|Sun, Ning\|Lu, Chao\|Qian, Ruizhe\|Hua, Luchun
PMID:	23970287

101.
Journal:	Biochimie. 2013 Nov;95(11):2157-67.
Title:	Antitumour activity on extrinsic apoptotic targets of the triterpenoid maslinic acid in p53-deficient Caco-2 adenocarcinoma cells.
Author:	Reyes-Zurita, Fernando J\|Rufino-Palomares, Eva E\|Medina, Pedro P\|Leticia Garcia-Salguero, E\|Peragon, Juan\|Cascante, Marta\|Lupianez, Jose A
PMID:	23973282

102.
Journal:	Mol Cells. 2013 Sep;36(3):219-26.
Title:	Midazolam induces cellular apoptosis in human cancer cells and inhibits tumor growth in xenograft mice.
Author:	Mishra, Siddhartha Kumar\|Kang, Ju-Hee\|Lee, Chang Woo\|Oh, Seung Hyun\|Ryu, Jun Sun\|Bae, Yun Soo\|Kim, Hwan Mook
PMID:	24008365

103.
Journal:	World J Gastroenterol. 2013 Sep 7;19(33):5520-7.
Title:	Diffusion-weighted magnetic resonance imaging for predicting the response of rectal cancer to neoadjuvant concurrent chemoradiation.
Author:	Cai, Gang\|Xu, Ye\|Zhu, Ji\|Gu, Wei-Lie\|Zhang, Shuai\|Ma, Xue-Jun\|Cai, San-Jun\|Zhang, Zhen
PMID:	24023496

104.
Journal:	Pathol Oncol Res. 2014 Apr;20(2):301-7.
Title:	Down-regulation of BAX gene during carcinogenesis and acquisition of resistance to 5-FU in colorectal cancer.
Author:	Manoochehri, Mehdi\|Karbasi, Ashraf\|Bandehpour, Mojgan\|Kazemi, Bahram
PMID:	24122668

105.
Journal:	Genes Nutr. 2014 Jan;9(1):359.
Title:	The fermented non-digestible fraction of common bean (Phaseolus vulgaris L.) triggers cell cycle arrest and apoptosis in human colon adenocarcinoma cells.
Author:	Cruz-Bravo, R K\|Guevara-Gonzalez, R G\|Ramos-Gomez, M\|Oomah, B D\|Wiersma, P\|Campos-Vega, R\|Loarca-Pina, G
PMID:	24293398

106.
Journal:	Int J Mol Sci. 2014 Feb 17;15(2):2722-37.
Title:	Mechanisms underlying apoptosis-inducing effects of Kaempferol in HT-29 human colon cancer cells.
Author:	Lee, Hyun Sook\|Cho, Han Jin\|Yu, Rina\|Lee, Ki Won\|Chun, Hyang Sook\|Park, Jung Han Yoon
PMID:	24549175

107.
Journal:	Oncol Rep. 2014 Apr;31(4):1788-94.
Title:	Tangeretin, a citrus polymethoxyflavonoid, induces apoptosis of human gastric cancer AGS cells through extrinsic and intrinsic signaling pathways.
Author:	Dong, Yang\|Cao, Aili\|Shi, Jianrong\|Yin, Peihao\|Wang, Li\|Ji, Guang\|Xie, Jianqun\|Wu, Dazheng
PMID:	24573532

108.
Journal:	Asian Pac J Cancer Prev. 2014;15(4):1567-74.
Title:	Mortality of major cancers in Guangxi, China: sex, age and geographical differences from 1971 and 2005.
Author:	Deng, Wei\|Long, Long\|Li, Ji-Lin\|Zheng, Dan\|Yu, Jia-Hua\|Zhang, Chun-Yan\|Li, Ke-Zhi\|Liu, Hai-Zhou\|Huang, Tian-Ren
PMID:	24641369

109.
Journal:	Oncol Lett. 2014 May;7(5):1728-1732.
Title:	Laminarin-induced apoptosis in human colon cancer LoVo cells.
Author:	Ji, Chen-Feng\|Ji, Yu-Bin
PMID:	24765209

110.
Journal:	J Dig Dis. 2014 Sep;15(9):491-500.
Title:	Silencing of JMJD2B induces cell apoptosis via mitochondria-mediated and death receptor-mediated pathway activation in colorectal cancer.
Author:	Sun, Bei Bei\|Fu, Lin Na\|Wang, Yun Qian\|Gao, Qin Yan\|Xu, Jie\|Cao, Zhi Jun\|Chen, Ying Xuan\|Fang, Jing Yuan
PMID:	24957706

111.
Journal:	Apoptosis. 2014 Oct;19(10):1532-44.
Title:	Urokinase-type plasminogen activator receptor regulates apoptotic sensitivity of colon cancer HCT116 cell line to TRAIL via JNK-p53 pathway.
Author:	Liu, Xiufeng\|Qiu, Fan\|Liu, Zhipeng\|Lan, Yan\|Wang, Kai\|Zhou, Ping-Kun\|Wang, Yao\|Hua, Zi-Chun
PMID:	25113506

112.
Journal:	Environ Toxicol Pharmacol. 2014 Sep;38(2):489-501.
Title:	NCI in vitro and in silico anticancer screen, cell cycle pertubation and apoptosis-inducing potential of new acylated, benzylidene and isopropylidene derivatives of andrographolide.
Author:	Wong, Charng Choon\|Sagineedu, Sreenivasa Rao\|Sumon, Shariful Hasan\|Sidik, Shiran Mohamad\|Phillips, Roger\|Lajis, Nordin H\|Stanslas, Johnson
PMID:	25168151

113.
Journal:	BMC Cancer. 2014 Nov 24;14:875.
Title:	Phase 1/2 study of valproic acid and short-course radiotherapy plus capecitabine as preoperative treatment in low-moderate risk rectal cancer-V-shoRT-R3 (Valproic acid--short Radiotherapy--rectum 3rd trial).
Author:	Avallone, Antonio\|Piccirillo, Maria Carmela\|Delrio, Paolo\|Pecori, Biagio\|Di Gennaro, Elena\|Aloj, Luigi\|Tatangelo, Fabiana\|D'Angelo, Valentina\|Granata, Cinzia\|Cavalcanti, Ernesta\|Maurea, Nicola\|Maiolino, Piera\|Bianco, Franco\|Montano, Massimo\|Silvestro, Luc
PMID:	25421252

114.
Journal:	Mol Cancer Res. 2015 Feb;13(2):281-92.
Title:	Bile acids regulate nuclear receptor (Nur77) expression and intracellular location to control proliferation and apoptosis.
Author:	Hu, Ying\|Chau, Thinh\|Liu, Hui-Xin\|Liao, Degui\|Keane, Ryan\|Nie, Yuqiang\|Yang, Hui\|Wan, Yu-Jui Yvonne
PMID:	25232032

115.
Journal:	Cell Biochem Biophys. 2015 Sep;73(1):137-45.
Title:	Dihydroartemisinin-Induced Apoptosis is Associated with Inhibition of Sarco/Endoplasmic Reticulum Calcium ATPase Activity in Colorectal Cancer.
Author:	Lu, Min\|Sun, Luhaoran\|Zhou, Jin\|Zhao, Yan\|Deng, Xin
PMID:	25701954

116.
Journal:	Int J Mol Sci. 2015 Mar 9;16(3):5386-99.
Title:	Different apoptotic pathways activated by oxaliplatin in primary astrocytes vs. colo-rectal cancer cells.
Author:	Zanardelli, Matteo\|Micheli, Laura\|Nicolai, Raffaella\|Failli, Paola\|Ghelardini, Carla\|Di Cesare Mannelli, Lorenzo
PMID:	25761243

117.
Journal:	Acta Pharmacol Sin. 2015 Sep;36(9):1074-84.
Title:	New benzimidazole acridine derivative induces human colon cancer cell apoptosis in vitro via the ROS-JNK signaling pathway.
Author:	Chen, Kang\|Chu, Bi-zhu\|Liu, Feng\|Li, Bin\|Gao, Chun-mei\|Li, Lu-lu\|Sun, Qin-sheng\|Shen, Zhi-fa\|Jiang, Yu-yang
PMID:	26235743

118.
Journal:	PLoS One. 2016 Jan 11;11(1):e0146178.
Title:	Maslinic Acid, a Natural Triterpene, Induces a Death Receptor-Mediated Apoptotic Mechanism in Caco-2 p53-Deficient Colon Adenocarcinoma Cells.
Author:	Reyes-Zurita, Fernando J\|Rufino-Palomares, Eva E\|Garcia-Salguero, Leticia\|Peragon, Juan\|Medina, Pedro P\|Parra, Andres\|Cascante, Marta\|Lupianez, Jose A
PMID:	26751572

119.
Journal:	J Biol Chem. 2016 May 27;291(22):11843-51.
Title:	Cleavage by Caspase 8 and Mitochondrial Membrane Association Activate the BH3-only Protein Bid during TRAIL-induced Apoptosis.
Author:	Huang, Kai\|Zhang, Jingjing\|O'Neill, Katelyn L\|Gurumurthy, Channabasavaiah B\|Quadros, Rolen M\|Tu, Yaping\|Luo, Xu
PMID:	27053107

120.
Journal:	J Nat Prod. 2016 Apr 22;79(4):1097-104.
Title:	Antitumor Activity of Spicatoside A by Modulation of Autophagy and Apoptosis in Human Colorectal Cancer Cells.
Author:	Kim, Won Kyung\|Pyee, Yuna\|Chung, Hwa-Jin\|Park, Hyen Joo\|Hong, Ji-Young\|Son, Kun Ho\|Lee, Sang Kook
PMID:	27064730

121.
Journal:	PLoS One. 2016 Apr 12;11(4):e0152652.
Title:	Cycloart-24-ene-26-ol-3-one, a New Cycloartane Isolated from Leaves of Aglaia exima Triggers Tumour Necrosis Factor-Receptor 1-Mediated Caspase-Dependent Apoptosis in Colon Cancer Cell Line.
Author:	Leong, Kok Hoong\|Looi, Chung Yeng\|Loong, Xe-Min\|Cheah, Foo Kit\|Supratman, Unang\|Litaudon, Marc\|Mustafa, Mohd Rais\|Awang, Khalijah
PMID:	27070314

122.
Journal:	Biomol Ther (Seoul). 2016 May 1;24(3):320-7.
Title:	Columbianadin Inhibits Cell Proliferation by Inducing Apoptosis and Necroptosis in HCT116 Colon Cancer Cells.
Author:	Kang, Ji In\|Hong, Ji-Young\|Choi, Jae Sue\|Lee, Sang Kook
PMID:	27098859

123.
Journal:	Oncol Rep. 2016 Jul;36(1):205-14.
Title:	Hwang-Heuk-San induces apoptosis in HCT116 human colorectal cancer cells through the ROS-mediated activation of caspases and the inactivation of the PI3K/Akt signaling pathway.
Author:	Lee, Moon Hee\|Hong, Su-Hyun\|Park, Cheol\|Kim, Gi-Young\|Leem, Sun-Hee\|Choi, Sung Hyun\|Keum, Young-Sam\|Hyun, Jin Won\|Kwon, Taeg Kyu\|Hong, Sang Hoon\|Choi, Yung Hyun
PMID:	27221553

124.
Journal:	Toxicol Lett. 2016 Aug 22;257:84-96.
Title:	Isoledene from Mesua ferrea oleo-gum resin induces apoptosis in HCT 116 cells through ROS-mediated modulation of multiple proteins in the apoptotic pathways: A mechanistic study.
Author:	Asif, Muhammad\|Shafaei, Armaghan\|Jafari, Seyedeh Fatemeh\|Mohamed, Shazmin Kithur\|Ezzat, Mohammed Oday\|Abdul Majid, Aman Shah\|Oon, Chern Ein\|Petersen, Sven H\|Kono, Koji\|Abdul Majid, Amin Malik Shah
PMID:	27268964

125.
Journal:	Molecules. 2016 Jun 4;21(6). pii: molecules21060730.
Title:	Dioscin Induces Apoptosis in Human Cervical Carcinoma HeLa and SiHa Cells through ROS-Mediated DNA Damage and the Mitochondrial Signaling Pathway.
Author:	Zhao, Xinwei\|Tao, Xufeng\|Xu, Lina\|Yin, Lianhong\|Qi, Yan\|Xu, Youwei\|Han, Xu\|Peng, Jinyong
PMID:	27271587

126.
Journal:	Molecules. 2016 Jul 19;21(7). pii: molecules21070934.
Title:	Protocatechualdehyde Induces S-Phase Arrest and Apoptosis by Stimulating the p27(KIP1)-Cyclin A/D1-CDK2 and Mitochondrial Apoptotic Pathways in HT-29 Cells.
Author:	Zhong, Shi\|Li, You-Gui\|Ji, Dong-Feng\|Lin, Tian-Bao\|Lv, Zhi-Qiang
PMID:	27447597

127.
Journal:	BMC Cancer. 2016 Jul 27;16:545.
Title:	Bifidobacterial recombinant thymidine kinase-ganciclovir gene therapy system induces FasL and TNFR2 mediated antitumor apoptosis in solid tumors.
Author:	Wang, Changdong\|Ma, Yongping\|Hu, Qiongwen\|Xie, Tingting\|Wu, Jiayan\|Zeng, Fan\|Song, Fangzhou
PMID:	27464624

128.
Journal:	Sci Rep. 2016 Sep 13;6:32979.
Title:	Crocetin exploits p53-induced death domain (PIDD) and FAS-associated death domain (FADD) proteins to induce apoptosis in colorectal cancer.
Author:	Ray, Pallab\|Guha, Deblina\|Chakraborty, Juni\|Banerjee, Shuvomoy\|Adhikary, Arghya\|Chakraborty, Samik\|Das, Tanya\|Sa, Gaurisankar
PMID:	27622714

129.
Journal:	BMC Complement Altern Med. 2016 Oct 1;16(1):384.
Title:	Methylferulate from Tamarix aucheriana inhibits growth and enhances chemosensitivity of human colorectal cancer cells: possible mechanism of action.
Author:	Abaza, Mohamed Salah I\|Afzal, Mohammad\|Al-Attiyah, Raja'a J\|Guleri, Radhika
PMID:	27716288

130.
Journal:	Oncol Rep. 2017 Feb;37(2):1132-1140.
Title:	Apigenin induces both intrinsic and extrinsic pathways of apoptosis in human colon carcinoma HCT-116 cells.
Author:	Wang, Bo\|Zhao, Xin-Huai
PMID:	27959417

131.
Journal:	Oncol Rep. 2017 Jan;37(1):571-578.
Title:	miR-20a-directed regulation of BID is associated with the TRAIL sensitivity in colorectal cancer.
Author:	Huang, Guanli\|Chen, Xiangjian\|Cai, Yefeng\|Wang, Xiaobo\|Xing, Chungen
PMID:	28004114

132.
Journal:	PLoS One. 2017 Jan 9;12(1):e0168989.
Title:	CIL-102-Induced Cell Cycle Arrest and Apoptosis in Colorectal Cancer Cells via Upregulation of p21 and GADD45.
Author:	Huang, Wen-Shih\|Kuo, Yi-Hung\|Kuo, Hsing-Chun\|Hsieh, Meng-Chiao\|Huang, Cheng-Yi\|Lee, Ko-Chao\|Lee, Kam-Fai\|Shen, Chien-Heng\|Tung, Shui-Yi\|Teng, Chih-Chuan
PMID:	28068431

133.
Journal:	Integr Cancer Ther. 2018 Jun;17(2):271-281.
Title:	Scorpion Venom Causes Upregulation of p53 and Downregulation of Bcl-xL and BID Protein Expression by Modulating Signaling Proteins Erk(1/2) and STAT3, and DNA Damage in Breast and Colorectal Cancer Cell Lines.
Author:	Al-Asmari, Abdulrahman Khazim\|Riyasdeen, Anvarbatcha\|Islam, Mozaffarul
PMID:	28438053

134.
Journal:	Curr Drug Saf. 2018;13(1):55-58.
Title:	A Case of Capecitabine-induced Hyperammonemia in a Patient with Colon Cancer.
Author:	Fang, Wentong\|Fu, Yuanyuan\|Wei, Jifu
PMID:	28782476

135.
Journal:	Oncol Rep. 2018 Jan;39(1):61-70.
Title:	Crosstalk between p38 MAPK and caspase-9 regulates mitochondria-mediated apoptosis induced by tetra-alpha-(4-carboxyphenoxy) phthalocyanine zinc photodynamic therapy in LoVo cells.
Author:	Wang, Yu\|Xia, Chunhui\|Lun, Zhiqiang\|Lv, Yanxin\|Chen, Wei\|Li, Tao
PMID:	29115534

136.
Journal:	Clin Colorectal Cancer. 2018 Jun;17(2):e257-e268.
Title:	A Phase I Study of Irinotecan, Capecitabine (Xeloda), and Oxaliplatin in Patients With Advanced Colorectal Cancer.
Author:	Maroun, Jean\|Marginean, Horia\|Jonker, Derek\|Cripps, Christine\|Goel, Rakesh\|Asmis, Timothy\|Goodwin, Rachel\|Chiritescu, Gabriela
PMID:	29330005

137.
Journal:	World J Gastrointest Oncol. 2018 Jan 15;10(1):40-47.
Title:	Neoadjuvant hyperfractionated accelerated radiotherapy plus concomitant 5-fluorouracil infusion in locally advanced rectal cancer: A phase II study.
Author:	Gural, Zeynep\|Saglam, Sezer\|Yucel, Serap\|Kaytan-Saglam, Esra\|Asoglu, Oktar\|Ordu, Cetin\|Acun, Hediye\|Sharifov, Rasul\|Onder, Semen\|Kizir, Ahmet\|Oral, Ethem N
PMID:	29375747

138.
Journal:	Oncotarget. 2017 Dec 4;9(3):3278-3291.
Title:	Vitexin induces apoptosis by suppressing autophagy in multi-drug resistant colorectal cancer cells.
Author:	Bhardwaj, Monika\|Cho, Hee Jun\|Paul, Souren\|Jakhar, Rekha\|Khan, Imran\|Lee, Seon-Jin\|Kim, Bo-Yeon\|Krishnan, Manigandan\|Khaket, Tejinder Pal\|Lee, Hee Gu\|Kang, Sun Chul
PMID:	29423046

139.
Journal:	Phytother Res. 2018 Apr;32(4):657-666.
Title:	Antiproliferative activity and apoptosis induction by trijuganone C isolated from the root of Salvia miltiorrhiza Bunge (Danshen).
Author:	Uto, Takuhiro\|Tung, Nguyen Huu\|Ohta, Tomoe\|Juengsanguanpornsuk, Wipawee\|Hung, Le Quoc\|Hai, Nguyen Thanh\|Long, Dinh Doan\|Thuong, Phuong Thien\|Okubo, Shinya\|Hirata, Sakiko\|Shoyama, Yukihiro
PMID:	29464799

140.
Journal:	Cell Death Discov. 2018 Feb 8;4:11.
Title:	PLEKHN1 promotes apoptosis by enhancing Bax-Bak hetro-oligomerization through interaction with Bid in human colon cancer.
Author:	Kuriyama, Sei\|Tsuji, Tadahiro\|Sakuma, Tetsushi\|Yamamoto, Takashi\|Tanaka, Masamistu
PMID:	29531808

141.
Journal:	Phytother Res. 2018 Jun 7.
Title:	Reactive oxygen species-mediated phosphorylation of p38 signaling is critically involved in apoptotic effect of Tanshinone I in colon cancer cells.
Author:	Kim, Dong Hee\|Shin, Eun Ah\|Kim, Bonglee\|Shim, Bum Sang\|Kim, Sung-Hoon
PMID:	29876988

142.
Journal:	Cancer Med. 2018 Aug 19.
Title:	Randomized, double-blind, phase two study of ruxolitinib plus regorafenib in patients with relapsed/refractory metastatic colorectal cancer.
Author:	Fogelman, David\|Cubillo, Antonio\|Garcia-Alfonso, Pilar\|Miron, Maria Luisa Limon\|Nemunaitis, John\|Flora, Daniel\|Borg, Christophe\|Mineur, Laurent\|Vieitez, Jose M\|Cohn, Allen\|Saylors, Gene\|Assad, Albert\|Switzky, Julie\|Zhou, Li\|Bendell, Johanna
PMID:	30123970

143.
Journal:	Int J Biochem Cell Biol. 2018 Oct;103:89-98.
Title:	Lysosomal permeabilization and endoplasmic reticulum stress mediate the apoptotic response induced after photoactivation of a lipophilic zinc(II) phthalocyanine.
Author:	Chiarante, Nicolas\|Garcia Vior, Maria C\|Rey, Osvaldo\|Marino, Julieta\|Roguin, Leonor P
PMID:	30130653