Primary Site >> Liver Cancer

Gene >> BHMT

Journal: J Biol Chem. 2011 Oct 21;286(42):36258-67.
Title: Deletion of betaine-homocysteine S-methyltransferase in mice perturbs choline and 1-carbon metabolism, resulting in fatty liver and hepatocellular carcinomas.
Author: Teng, Ya-Wen|Mehedint, Mihai G|Garrow, Timothy A|Zeisel, Steven H
PMID: 21878621
Journal: Int J Biochem Cell Biol. 2012 Feb;44(2):385-92.
Title: A splicing variant leads to complete loss of function of betaine-homocysteine methyltransferase (BHMT) gene in hepatocellular carcinoma.
Author: Pellanda, Helene|Namour, Fares|Fofou-Caillierez, Ma'atem|Bressenot, Aude|Alberto, Jean-Marc|Chery, Celine|Ayav, Ahmet|Bronowicki, Jean-Pierre|Gueant, Jean-Louis|Forges, Thierry
PMID: 22138536
Journal: Cell Oncol (Dordr). 2012 Jun;35(3):163-73.
Title: An expression signature of phenotypic resistance to hepatocellular carcinoma identified by cross-species gene expression analysis.
Author: Frau, Maddalena|Simile, Maria M|Tomasi, Maria L|Demartis, Maria I|Daino, Lucia|Seddaiu, Maria A|Brozzetti, Stefania|Feo, Claudio F|Massarelli, Giovanni|Solinas, Giuliana|Feo, Francesco|Lee, Ju-Seog|Pascale, Rosa M
PMID: 22434528
Journal: Clin Chem Lab Med. 2013 Mar 1;51(3):617-21.
Title: Betaine homocysteine methyltransferase (BHMT)-dependent remethylation pathway in human healthy and tumoral liver.
Author: Pellanda, Helene
PMID: 23449526
Journal: Mol Cell Proteomics. 2013 Jul;12(7):2006-20.
Title: Proteomic differences between hepatocellular carcinoma and nontumorous liver tissue investigated by a combined gel-based and label-free quantitative proteomics study.
Author: Megger, Dominik A|Bracht, Thilo|Kohl, Michael|Ahrens, Maike|Naboulsi, Wael|Weber, Frank|Hoffmann, Andreas-Claudius|Stephan, Christian|Kuhlmann, Katja|Eisenacher, Martin|Schlaak, Jorg F|Baba, Hideo A|Meyer, Helmut E|Sitek, Barbara
PMID: 23462207
Journal: Pathology. 2015 Oct;47(6):543-50.
Title: Differential proteomic and tissue expression analyses identify valuable diagnostic biomarkers of hepatocellular differentiation and hepatoid adenocarcinomas.
Author: Reis, Henning|Padden, Juliet|Ahrens, Maike|Putter, Carolin|Bertram, Stefanie|Pott, Leona L|Reis, Anna-Carinna|Weber, Frank|Juntermanns, Benjamin|Hoffmann, Andreas-C|Eisenacher, Martin|Schlaak, Joorg F|Canbay, Ali|Meyer, Helmut E|Sitek, Barbara|Baba, Hideo
PMID: 26308133
Journal: Tumour Biol. 2016 May;37(5):5911-7.
Title: Downregulation of betaine homocysteine methyltransferase (BHMT) in hepatocellular carcinoma associates with poor prognosis.
Author: Jin, Bin|Gong, Zhiwei|Yang, Nongguo|Huang, Zhaoquan|Zeng, Sien|Chen, Hui|Hu, Sanyuan|Pan, Guangdong
PMID: 26592251
Journal: Onco Targets Ther. 2016 Aug 22;9:5225-33.
Title: Association between BHMT gene rs3733890 polymorphism and cancer risk: evidence from a meta-analysis.
Author: Xu, Yue|Yan, Cunye|Hao, Zongyao|Zhou, Jun|Fan, Song|Tai, Sheng|Yang, Cheng|Zhang, Li|Liang, Chaozhao
PMID: 27578989
Journal: PLoS One. 2016 Dec 9;11(12):e0167534.
Title: The RFC1 80G>A, among Common One-Carbon Polymorphisms, Relates to Survival Rate According to DNA Global Methylation in Primary Liver Cancers.
Author: Moruzzi, Sara|Udali, Silvia|Ruzzenente, Andrea|Guglielmi, Alfredo|Guarini, Patrizia|Martinelli, Nicola|Conci, Simone|Mazzi, Filippo|Pattini, Patrizia|Tammen, Stephanie A|Olivieri, Oliviero|Pizzolo, Francesca|Choi, Sang-Woon|Friso, Simonetta
PMID: 27936032
Journal: Pathol Res Pract. 2017 Apr;213(4):316-321.
Title: Aberrant expression of cell cycle and material metabolism related genes contributes to hepatocellular carcinoma occurrence.
Author: Yan, Hongxian|Li, Zhaohui|Shen, Quan|Wang, Qian|Tian, Jianguo|Jiang, Qingfeng|Gao, Linbo
PMID: 28238542
Journal: Nutrients. 2017 Apr 29;9(5). pii: nu9050445.
Title: Choline, Other Methyl-Donors and Epigenetics.
Author: Zeisel, Steven
PMID: 28468239
Journal: PLoS One. 2017 Oct 2;12(10):e0185792.
Title: One-carbon genetic variants and the role of MTHFD1 1958G>A in liver and colon cancer risk according to global DNA methylation.
Author: Moruzzi, Sara|Guarini, Patrizia|Udali, Silvia|Ruzzenente, Andrea|Guglielmi, Alfredo|Conci, Simone|Pattini, Patrizia|Martinelli, Nicola|Olivieri, Oliviero|Tammen, Stephanie A|Choi, Sang-Woon|Friso, Simonetta
PMID: 28968444
Journal: Arch Toxicol. 2018 Oct 24. pii: 10.1007/s00204-018-2332-7.
Title: Gut microbiome disruption altered the biotransformation and liver toxicity of arsenic in mice.
Author: Chi, Liang|Xue, Jingchuan|Tu, Pengcheng|Lai, Yunjia|Ru, Hongyu|Lu, Kun
PMID: 30357543