Primary Site >> Liver Cancer

Gene >> BHMT

  • 2011
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  • 2018
Ref: Deletion of betaine-homocysteine S-methyltransferase in mice perturbs choline and 1-carbon metabolism, resulting in fatty liver and hepatocellular carcinomas.
PMID: 21878621
Ref: A splicing variant leads to complete loss of function of betaine-homocysteine methyltransferase (BHMT) gene in hepatocellular carcinoma.
PMID: 22138536
Ref: An expression signature of phenotypic resistance to hepatocellular carcinoma identified by cross-species gene expression analysis.
PMID: 22434528
Ref: Betaine homocysteine methyltransferase (BHMT)-dependent remethylation pathway in human healthy and tumoral liver.
PMID: 23449526
Ref: Proteomic differences between hepatocellular carcinoma and nontumorous liver tissue investigated by a combined gel-based and label-free quantitative proteomics study.
PMID: 23462207
Ref: Differential proteomic and tissue expression analyses identify valuable diagnostic biomarkers of hepatocellular differentiation and hepatoid adenocarcinomas.
PMID: 26308133
Ref: Downregulation of betaine homocysteine methyltransferase (BHMT) in hepatocellular carcinoma associates with poor prognosis.
PMID: 26592251
Ref: Association between BHMT gene rs3733890 polymorphism and cancer risk: evidence from a meta-analysis.
PMID: 27578989
Ref: The RFC1 80G>A, among Common One-Carbon Polymorphisms, Relates to Survival Rate According to DNA Global Methylation in Primary Liver Cancers.
PMID: 27936032
Ref: Aberrant expression of cell cycle and material metabolism related genes contributes to hepatocellular carcinoma occurrence.
PMID: 28238542
Ref: Choline, Other Methyl-Donors and Epigenetics.
PMID: 28468239
Ref: One-carbon genetic variants and the role of MTHFD1 1958G>A in liver and colon cancer risk according to global DNA methylation.
PMID: 28968444
Ref: Gut microbiome disruption altered the biotransformation and liver toxicity of arsenic in mice.
PMID: 30357543