Primary Site >> Colorectal Cancer

Gene >> BECN1

Journal: Nihon Rinsho. 2003 Sep;61 Suppl 7:247-51.
Title: [Analysis of cell cycle inhibition by novel tumor suppressor gene Beclin 1 in human colon cancer cells].
Author: Koneri, Kenji|Goi, Takanori|Yamaguchi, Akio
PMID: 14574891
Journal: Nat Cell Biol. 2006 Jul;8(7):688-99. Epub 2006 Jun 25.
Title: Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG.
Author: Liang, Chengyu|Feng, Pinghui|Ku, Bonsu|Dotan, Iris|Canaani, Dan|Oh, Byung-Ha|Jung, Jae U
PMID: 16799551
Journal: Anticancer Res. 2007 May-Jun;27(3B):1453-7.
Title: Beclin 1 gene inhibits tumor growth in colon cancer cell lines.
Author: Koneri, Kenji|Goi, Takanori|Hirono, Yasuo|Katayama, Kanji|Yamaguchi, Akio
PMID: 17595761
Journal: APMIS. 2007 Jun;115(6):750-6.
Title: Somatic mutations of BECN1, an autophagy-related gene, in human cancers.
Author: Lee, Jong Woo|Jeong, Eun Goo|Lee, Sung Hak|Yoo, Nam Jin|Lee, Sug Hyung
PMID: 17550384
Journal: APMIS. 2007 Dec;115(12):1344-9.
Title: Expression of beclin-1, an autophagy-related protein, in gastric and colorectal cancers.
Author: Ahn, Chang Hyeok|Jeong, Eun Goo|Lee, Jong Woo|Kim, Min Sung|Kim, Sung Hee|Kim, Sung Soo|Yoo, Nam Jin|Lee, Sug Hyung
PMID: 18184403
Journal: Carcinogenesis. 2008 Feb;29(2):381-9.
Title: Resveratrol-induced apoptosis depends on the lipid kinase activity of Vps34 and on the formation of autophagolysosomes.
Author: Trincheri, Nicol F|Follo, Carlo|Nicotra, Giuseppina|Peracchio, Claudia|Castino, Roberta|Isidoro, Ciro
PMID: 18048384
Journal: Hum Pathol. 2008 Jul;39(7):1059-63.
Title: Frameshift mutation of UVRAG, an autophagy-related gene, in gastric carcinomas with microsatellite instability.
Author: Kim, Min Sung|Jeong, Eun Goo|Ahn, Chang Hyeok|Kim, Sung Soo|Lee, Sug Hyung|Yoo, Nam Jin
PMID: 18495205
Journal: Autophagy. 2009 Apr;5(3):303-6. Epub 2009 Apr 26.
Title: The expression of beclin 1 is associated with favorable prognosis in stage IIIB colon cancers.
Author: Li, Bao-Xiu|Li, Chun-Yan|Peng, Rui-Qing|Wu, Xiao-Jun|Wang, Hai-Ying|Wan, De-Sen|Zhu, Xiao-Feng|Zhang, Xiao-Shi
PMID: 19066461
Journal: Mol Pharmacol. 2009 Aug;76(2):342-55.
Title: Sorafenib and vorinostat kill colon cancer cells by CD95-dependent and -independent mechanisms.
Author: Walker, Teneille|Mitchell, Clint|Park, Margaret A|Yacoub, Adly|Graf, Martin|Rahmani, Mohamed|Houghton, Peter J|Voelkel-Johnson, Christina|Grant, Steven|Dent, Paul
PMID: 19483104
Journal: J Hepatol. 2009 Nov;51(5):881-9.
Title: Concurrent induction of necrosis, apoptosis, and autophagy in ischemic preconditioned human livers formerly treated by chemotherapy.
Author: Domart, Marie-Charlotte|Esposti, Davide Degli|Sebagh, Mylene|Olaya, Natalia|Harper, Francis|Pierron, Gerard|Franc, Brigitte|Tanabe, Kenneth K|Debuire, Brigitte|Azoulay, Daniel|Brenner, Catherine|Lemoine, Antoinette
PMID: 19765849
Journal: J Toxicol. 2009;2009:785907.
Title: Deoxycholate, an endogenous cytotoxin/genotoxin, induces the autophagic stress-survival pathway: implications for colon carcinogenesis.
Author: Payne, Claire M|Crowley-Skillicorn, Cheray|Holubec, Hana|Dvorak, Katerina|Bernstein, Carol|Moyer, Mary Pat|Garewal, Harinder|Bernstein, Harris
PMID: 20130808
Journal: PLoS One. 2010 Jan 18;5(1):e8755.
Title: Differential dependence on Beclin 1 for the regulation of pro-survival autophagy by Bcl-2 and Bcl-xL in HCT116 colorectal cancer cells.
Author: Priault, Muriel|Hue, Erika|Marhuenda, Fanny|Pilet, Paul|Oliver, Lisa|Vallette, Francois M
PMID: 20090905
Journal: Lett Appl Microbiol. 2010 Aug;51(2):123-30.
Title: Cell-bound exopolysaccharide from probiotic bacteria induces autophagic cell death of tumour cells.
Author: Kim, Y|Oh, S|Yun, H S|Oh, S|Kim, S H
PMID: 20536712
Journal: Br J Cancer. 2010 Oct 12;103(8):1209-14.
Title: Beclin 1 over- and underexpression in colorectal cancer: distinct patterns relate to prognosis and tumour hypoxia.
Author: Koukourakis, M I|Giatromanolaki, A|Sivridis, E|Pitiakoudis, M|Gatter, K C|Harris, A L
PMID: 20842118
Journal: Cancer Res. 2010 Oct 1;70(19):7699-709.
Title: Inhibition of autophagy enhances anticancer effects of atorvastatin in digestive malignancies.
Author: Yang, Pei-Ming|Liu, Yuan-Ling|Lin, Yi-Chu|Shun, Chia-Tung|Wu, Ming-Shiang|Chen, Ching-Chow
PMID: 20876807
Journal: Cancer Res. 2011 May 15;71(10):3625-34.
Title: Following cytochrome c release, autophagy is inhibited during chemotherapy-induced apoptosis by caspase 8-mediated cleavage of Beclin 1.
Author: Li, Hua|Wang, Peng|Sun, Quanhong|Ding, Wen-Xing|Yin, Xiao-Ming|Sobol, Robert W|Stolz, Donna B|Yu, Jian|Zhang, Lin
PMID: 21444671
Journal: World J Gastroenterol. 2011 Nov 21;17(43):4779-86.
Title: Autophagy-related proteins Beclin-1 and LC3 predict cetuximab efficacy in advanced colorectal cancer.
Author: Guo, Gui-Fang|Jiang, Wen-Qi|Zhang, Bei|Cai, Yu-Chen|Xu, Rui-Hua|Chen, Xu-Xian|Wang, Fang|Xia, Liang-Ping
PMID: 22147978
Journal: Fitoterapia. 2011 Dec;82(8):1258-64.
Title: L-securinine induced the human colon cancer SW480 cell autophagy and its molecular mechanism.
Author: Xia, Yong-Hui|Cheng, Chuan-Rong|Yao, Shu-Yan|Zhang, Qing|Wang, Ying|Ji, Zhao-Ning
PMID: 21907765
Journal: Free Radic Biol Med. 2011 Oct 1;51(7):1365-75.
Title: Bufalin induces autophagy-mediated cell death in human colon cancer cells through reactive oxygen species generation and JNK activation.
Author: Xie, Chuan-Ming|Chan, Wood Yee|Yu, Sidney|Zhao, Jun|Cheng, Christopher H K
PMID: 21763418
Journal: J Cell Biochem. 2011 Sep;112(9):2471-9.
Title: Induction of autophagy by dimethyl cardamonin is associated with proliferative arrest in human colorectal carcinoma HCT116 and LOVO cells.
Author: Ko, Hyeonseok|Kim, Young-Joo|Amor, Evangeline C|Lee, Jong Wha|Kim, Han-Cheon|Kim, Hee Ju|Yang, Hyun Ok
PMID: 21538483
Journal: Autophagy. 2012 May 1;8(5):846-8.
Title: Direct molecular interactions between HMGB1 and TP53 in colorectal cancer.
Author: Livesey, Kristen M|Kang, Rui|Zeh, Herbert J 3rd|Lotze, Michael T|Tang, Daolin
PMID: 22647615
Journal: Autophagy. 2012 Jun;8(6):893-902.
Title: Autophagy is active in normal colon mucosa.
Author: Groulx, Jean-Francois|Khalfaoui, Taoufik|Benoit, Yannick D|Bernatchez, Gerald|Carrier, Julie C|Basora, Nuria|Beaulieu, Jean-Francois
PMID: 22652752
Journal: Cancer Res. 2012 Jul 1;72(13):3238-50.
Title: DEDD interacts with PI3KC3 to activate autophagy and attenuate epithelial-mesenchymal transition in human breast cancer.
Author: Lv, Qi|Wang, Wei|Xue, Jianfei|Hua, Fang|Mu, Rong|Lin, Heng|Yan, Jun|Lv, Xiaoxi|Chen, Xiaoguang|Hu, Zhuo-Wei
PMID: 22719072
Journal: PLoS One. 2012;7(11):e51076.
Title: Autophagy protects against oxaliplatin-induced cell death via ER stress and ROS in Caco-2 cells.
Author: Shi, Yan|Tang, Bin|Yu, Pei-Wu|Tang, Bo|Hao, Ying-Xue|Lei, Xiao|Luo, Hua-Xing|Zeng, Dong-Zhu
PMID: 23226467
Journal: Autophagy. 2013 Dec;9(12):2126-39.
Title: BIX-01294 induces autophagy-associated cell death via EHMT2/G9a dysfunction and intracellular reactive oxygen species production.
Author: Kim, Yunha|Kim, Yong-Sook|Kim, Dong Eun|Lee, Jee Suk|Song, Ji Hoon|Kim, Ha-Gyeong|Cho, Dong-Hyung|Jeong, Seong-Yun|Jin, Dong-Hoon|Jang, Se Jin|Seol, Hyang-Sook|Suh, Young-Ah|Lee, Seung Jin|Kim, Choung-Soo|Koh, Jae-Young|Hwang, Jung Jin
PMID: 24322755
Journal: Cell Death Dis. 2013 Aug 1;4:e750.
Title: A ginseng metabolite, compound K, induces autophagy and apoptosis via generation of reactive oxygen species and activation of JNK in human colon cancer cells.
Author: Kim, A D|Kang, K A|Kim, H S|Kim, D H|Choi, Y H|Lee, S J|Kim, H S|Hyun, J W
PMID: 23907464
Journal: Int J Oncol. 2013 Jun;42(6):2134-40.
Title: Altered cardiac muscle mTOR regulation during the progression of cancer cachexia in the ApcMin/+ mouse.
Author: Manne, Nandini D P K|Lima, M|Enos, R T|Wehner, P|Carson, J A|Blough, Eric
PMID: 23589074
Journal: Clin Cancer Res. 2013 Jun 1;19(11):2995-3007.
Title: Autophagy inhibition sensitizes colon cancer cells to antiangiogenic and cytotoxic therapy.
Author: Selvakumaran, Muthu|Amaravadi, Ravi K|Vasilevskaya, Irina A|O'Dwyer, Peter J
PMID: 23461901
Journal: Mitochondrion. 2013 Sep;13(5):493-9.
Title: Resveratrol depletes mitochondrial DNA and inhibition of autophagy enhances resveratrol-induced caspase activation.
Author: Prabhu, Varun|Srivastava, Pragya|Yadav, Neelu|Amadori, Michael|Schneider, Andrea|Seshadri, Athul|Pitarresi, Jason|Scott, Rachael|Zhang, Honghao|Koochekpour, Shahriar|Gogada, Raghu|Chandra, Dhyan
PMID: 23088850
Journal: Dig Dis Sci. 2013 Oct;58(10):2887-94.
Title: Downregulation of Beclin 1 and impairment of autophagy in a small population of colorectal cancer.
Author: Chen, Zhihong|Li, Yanchun|Zhang, Chi|Yi, Hongmei|Wu, Chang|Wang, Junpu|Liu, Yuwu|Tan, Jieqiong|Wen, Jifang
PMID: 23812859
Journal: Apoptosis. 2014 Nov;19(11):1603-15.
Title: Role of Bcl-xL/Beclin-1 in synergistic apoptotic effects of secretory TRAIL-armed adenovirus in combination with mitomycin C and hyperthermia on colon cancer cells.
Author: Kim, Seog-Young|Lee, Dae-Hee|Song, Xinxin|Bartlett, David L|Kwon, Yong Tae|Lee, Yong J
PMID: 25156145
Journal: Cancer Biol Ther. 2014;15(12):1646-57.
Title: Regulation of dimethyl-fumarate toxicity by proteasome inhibitors.
Author: Booth, Laurence|Cruickshanks, Nichola|Tavallai, Seyedmehrad|Roberts, Jane L|Peery, Matthew|Poklepovic, Andrew|Dent, Paul
PMID: 25482938
Journal: Cell Death Dis. 2014 Oct 30;5:e1504.
Title: Role of AMP-activated protein kinase in cross-talk between apoptosis and autophagy in human colon cancer.
Author: Song, X|Kim, S-Y|Zhang, L|Tang, D|Bartlett, D L|Kwon, Y T|Lee, Y J
PMID: 25356873
Journal: Int J Mol Sci. 2014 Aug 18;15(8):14372-85.
Title: Beclin 1 expression is closely linked to colorectal carcinogenesis and distant metastasis of colorectal carcinoma.
Author: Zhang, Mei-Ying|Gou, Wen-Feng|Zhao, Shuang|Mao, Xiao-Yun|Zheng, Zhi-Hong|Takano, Yasuo|Zheng, Hua-Chuan
PMID: 25196438
Journal: World J Gastrointest Oncol. 2014 Jul 15;6(7):225-43.
Title: Novel diet-related mouse model of colon cancer parallels human colon cancer.
Author: Prasad, Anil R|Prasad, Shilpa|Nguyen, Huy|Facista, Alexander|Lewis, Cristy|Zaitlin, Beryl|Bernstein, Harris|Bernstein, Carol
PMID: 25024814
Journal: Asian Pac J Cancer Prev. 2014;15(11):4583-7.
Title: Prognostic significance of Beclin-1 expression in colorectal cancer: a meta-analysis.
Author: Han, Ye|Xue, Xiao-Feng|Shen, Hu-Gang|Guo, Xiao-Bo|Wang, Xu|Yuan, Bin|Guo, Xing-Po|Kuang, Yu-Ting|Zhi, Qiao-Ming|Zhao, Hong
PMID: 24969889
Journal: PLoS One. 2014 Jun 23;9(6):e100819.
Title: Beclin 1 and UVRAG confer protection from radiation-induced DNA damage and maintain centrosome stability in colorectal cancer cells.
Author: Park, Jae Myung|Tougeron, David|Huang, Shengbing|Okamoto, Koichi|Sinicrope, Frank A
PMID: 24956373
Journal: Sci Rep. 2014 Apr 15;4:4694.
Title: JNK confers 5-fluorouracil resistance in p53-deficient and mutant p53-expressing colon cancer cells by inducing survival autophagy.
Author: Sui, Xinbing|Kong, Na|Wang, Xian|Fang, Yong|Hu, Xiaotong|Xu, Yinghua|Chen, Wei|Wang, Kaifeng|Li, Da|Jin, Wei|Lou, Fang|Zheng, Yu|Hu, Hong|Gong, Liu|Zhou, Xiaoyun|Pan, Hongming|Han, Weidong
PMID: 24733045
Journal: Gastroenterol Res Pract. 2014;2014:179586.
Title: Absence of autophagy-related proteins expression is associated with poor prognosis in patients with colorectal adenocarcinoma.
Author: Choi, Ji Hye|Cho, Young-Seok|Ko, Yoon Ho|Hong, Soon Uk|Park, Jin Hee|Lee, Myung Ah
PMID: 24723943
Journal: PLoS One. 2014 Feb 26;9(2):e90151.
Title: Ambra1 is an essential regulator of autophagy and apoptosis in SW620 cells: pro-survival role of Ambra1.
Author: Gu, Wen|Wan, Daiwei|Qian, Qinyi|Yi, Bin|He, Zhilong|Gu, Yilin|Wang, Liang|He, Songbing
PMID: 24587252
Journal: Biochem Pharmacol. 2014 Mar 15;88(2):178-88.
Title: Role of Bcl-xL/Beclin-1 in interplay between apoptosis and autophagy in oxaliplatin and bortezomib-induced cell death.
Author: Kim, Seog-Young|Song, Xinxin|Zhang, Lin|Bartlett, David L|Lee, Yong J
PMID: 24486574
Journal: Biochem Biophys Res Commun. 2014 Jan 17;443(3):1041-7.
Title: VMP1 related autophagy and apoptosis in colorectal cancer cells: VMP1 regulates cell death.
Author: Qian, Qinyi|Zhou, Hao|Chen, Yan|Shen, Chenglong|He, Songbing|Zhao, Hua|Wang, Liang|Wan, Daiwei|Gu, Wen
PMID: 24365149
Journal: Biochem Biophys Res Commun. 2014 Jan 10;443(2):406-12.
Title: Dramatic suppression of colorectal cancer cell growth by the dual mTORC1 and mTORC2 inhibitor AZD-2014.
Author: Huo, Hai-zhong|Zhou, Zhi-yuan|Wang, Bing|Qin, Jian|Liu, Wen-yong|Gu, Yan
PMID: 24309100
Journal: World J Gastrointest Oncol. 2015 Nov 15;7(11):271-84.
Title: Autophagy in colorectal cancer: An important switch from physiology to pathology.
Author: Burada, Florin|Nicoli, Elena Raluca|Ciurea, Marius Eugen|Uscatu, Daniel Constantin|Ioana, Mihai|Gheonea, Dan Ionut
PMID: 26600927
Journal: BMC Cancer. 2015 Nov 19;15:919.
Title: Pan-Bcl-2 inhibitor Obatoclax is a potent late stage autophagy inhibitor in colorectal cancer cells independent of canonical autophagy signaling.
Author: Koehler, Bruno Christian|Jassowicz, Adam|Scherr, Anna-Lena|Lorenz, Stephan|Radhakrishnan, Praveen|Kautz, Nicole|Elssner, Christin|Weiss, Johanna|Jaeger, Dirk|Schneider, Martin|Schulze-Bergkamen, Henning
PMID: 26585594
Journal: Hum Pathol. 2015 Nov;46(11):1752-9.
Title: Autophagy-related genes Raptor, Rictor, and Beclin1 expression and relationship with multidrug resistance in colorectal carcinoma.
Author: Shuhua, Wu|Chenbo, Sun|Yangyang, Li|Xiangqian, Gao|Shuang, He|Tangyue, Li|Dong, Tian
PMID: 26363527
Journal: Eur J Pharmacol. 2015 Oct 15;765:217-27.
Title: Blockade of autophagy enhances proapoptotic potential of BI-69A11, a novel Akt inhibitor, in colon carcinoma.
Author: Pal, Ipsita|Parida, Sheetal|Prashanth Kumar, B N|Banik, Payel|Kumar Dey, Kaushik|Chakraborty, Sandipan|Bhutia, Sujit K|Mandal, Mahitosh
PMID: 26306675
Journal: Int J Clin Exp Pathol. 2015 Apr 1;8(4):3882-91. eCollection 2015.
Title: Expression and clinical significances of Beclin1, LC3 and mTOR in colorectal cancer.
Author: Wu, Shuhua|Sun, Chenbo|Tian, Dong|Li, Yangyang|Gao, Xiangqian|He, Shuang|Li, Tangyue
PMID: 26097572
Journal: PLoS One. 2015 Apr 29;10(4):e0126147.
Title: Chloroquine-enhanced efficacy of cisplatin in the treatment of hypopharyngeal carcinoma in xenograft mice.
Author: Zhao, Xing-guo|Sun, Rui-jie|Yang, Xiao-yan|Liu, Da-yu|Lei, Da-peng|Jin, Tong|Pan, Xin-liang
PMID: 25923669
Journal: Cancer Biol Ther. 2015;16(5):733-42.
Title: Differential regulation of autophagy and cell viability by ceramide species.
Author: Cruickshanks, Nichola|Roberts, Jane L|Bareford, M Danielle|Tavallai, Mehrad|Poklepovic, Andrew|Booth, Laurence|Spiegel, Sarah|Dent, Paul
PMID: 25803131
Journal: Autophagy. 2015;11(3):452-9.
Title: BAX and BAK1 are dispensable for ABT-737-induced dissociation of the BCL2-BECN1 complex and autophagy.
Author: Pedro, Jose Manuel Bravo-San|Wei, Yongjie|Sica, Valentina|Maiuri, Maria Chiara|Zou, Zhongju|Kroemer, Guido|Levine, Beth
PMID: 25715028
Journal: Int J Cancer. 2015 Sep 15;137(6):1498-502.
Title: Association of beclin 1 expression with response to neoadjuvant chemoradiation therapy in patients with locally advanced rectal carcinoma.
Author: Zaanan, Aziz|Park, Jae Myung|Tougeron, David|Huang, Shengbing|Wu, Tsung-Teh|Foster, Nathan R|Sinicrope, Frank A
PMID: 25708267
Journal: J Cell Physiol. 2015 Sep;230(9):2281-98.
Title: Nexavar/Stivarga and viagra interact to kill tumor cells.
Author: Tavallai, Mehrad|Hamed, Hossein A|Roberts, Jane L|Cruickshanks, Nichola|Chuckalovcak, John|Poklepovic, Andrew|Booth, Laurence|Dent, Paul
PMID: 25704960
Journal: Mol Med Rep. 2015 Apr;11(4):3160-6.
Title: Sann-Joong-Kuey-Jian-Tang decreases the protein expression of mammalian target of rapamycin but increases microtubule associated protein II light chain 3 expression to inhibit human BxPC3 pancreatic carcinoma cells.
Author: Su, Chin-Cheng
PMID: 25516264
Journal: Tumour Biol. 2015 Apr;36(4):2531-9.
Title: Knockdown of autophagy-related protein 6, Beclin-1, decreases cell growth, invasion, and metastasis and has a positive effect on chemotherapy-induced cytotoxicity in osteosarcoma cells.
Author: Zhang, Wei|Li, Qianyi|Song, Chao|Lao, Lifeng
PMID: 25427639
Journal: J Cell Physiol. 2015 Apr;230(4):930-46.
Title: Justicidin A-induced autophagy flux enhances apoptosis of human colorectal cancer cells via class III PI3K and Atg5 pathway.
Author: Won, Shen-Jeu|Yen, Cheng-Hsin|Liu, Hsiao-Sheng|Wu, Shan-Ying|Lan, Sheng-Hui|Jiang-Shieh, Ya-Fen|Lin, Chun-Nan|Su, Chun-Li
PMID: 25216025
Journal: Clin Res Hepatol Gastroenterol. 2015 Feb;39(1):98-106.
Title: High expression of Beclin-1 predicts favorable prognosis for patients with colorectal cancer.
Author: Yang, Zuli|Ghoorun, Roshan Ara|Fan, Xinjuan|Wu, Peihuang|Bai, Yang|Li, Jizheng|Chen, Hao|Wang, Lei|Wang, Jianping
PMID: 25130795
Journal: Basic Clin Pharmacol Toxicol. 2015 Jan;116(1):37-46.
Title: Modulation of imatinib cytotoxicity by selenite in HCT116 colorectal cancer cells.
Author: Abdel-Aziz, Amal Kamal|Azab, Samar Saad Eldeen|Youssef, Samar Samir|El-Sayed, Abeer Mostafa|El-Demerdash, Ebtehal|Shouman, Samia
PMID: 24930392
Journal: Oncotarget. 2015 Mar 30;6(9):7084-103.
Title: Autophagy-based survival prognosis in human colorectal carcinoma.
Author: Yang, Maopeng|Zhao, Hong|Guo, Li|Zhang, Qingyuan|Zhao, Ling|Bai, Shuping|Zhang, Minghui|Xu, Sanqi|Wang, Fujing|Wang, Xiaohong|Zhao, Bin
PMID: 25762626
Journal: Genet Mol Res. 2016 Apr 7;15(2). pii: gmr7704.
Title: Association of Beclin-1 and microRNA-30a expression with the severity and treatment response of colorectal cancer.
Author: Liu, L|Meng, T|Wang, Q S|Jin, H Z|Sun, Z Q|Jin, B|Fang, F|Wang, H J
PMID: 27173217
Journal: Oncotarget. 2016 Nov 29;7(48):79617-79628.
Title: miR-31 affects colorectal cancer cells by inhibiting autophagy in cancer-associated fibroblasts.
Author: Yang, Xiaodong|Xu, Xiaohui|Zhu, Junjia|Zhang, Shuyu|Wu, Yong|Wu, Yongyou|Zhao, Kui|Xing, Chungen|Cao, Jianping|Zhu, Hong|Li, Ming|Ye, Zhenyu|Peng, Wei
PMID: 27793031
Journal: Oncol Rep. 2016 Dec;36(6):3559-3567.
Title: Salidroside induces apoptosis and autophagy in human colorectal cancer cells through inhibition of PI3K/Akt/mTOR pathway.
Author: Fan, Xiang-Jun|Wang, Yao|Wang, Lei|Zhu, Mingyan
PMID: 27748934
Journal: Autophagy. 2016 Nov;12(11):2167-2182.
Title: ABHD5 interacts with BECN1 to regulate autophagy and tumorigenesis of colon cancer independent of PNPLA2.
Author: Peng, Yuan|Miao, Hongming|Wu, Shuang|Yang, Weiwen|Zhang, Yue|Xie, Ganfeng|Xie, Xiong|Li, Jianjun|Shi, Chunmeng|Ye, Lilin|Sun, Wei|Wang, Liting|Liang, Houjie|Ou, Juanjuan
PMID: 27559856
Journal: Mol Med Rep. 2016 Sep;14(3):2548-54.
Title: Co-expression of autophagic markers following photodynamic therapy in SW620 human colon adenocarcinoma cells.
Author: Ziolkowska, Barbara|Wozniak, Marta|Ziolkowski, Piotr
PMID: 27485939
Journal: World J Surg Oncol. 2016 Jul 22;14(1):189.
Title: Prognostic relevance of autophagy-related markers LC3, p62/sequestosome 1, Beclin-1 and ULK1 in colorectal cancer patients with respect to KRAS mutational status.
Author: Schmitz, Klaus Juergen|Ademi, Ceflije|Bertram, Stefanie|Schmid, Kurt Werner|Baba, Hideo Andreas
PMID: 27444698
Journal: Oncotarget. 2016 Aug 9;7(32):51174-51183.
Title: RNF216 contributes to proliferation and migration of colorectal cancer via suppressing BECN1-dependent autophagy.
Author: Wang, Hui|Wang, Yanan|Qian, Liu|Wang, Xue|Gu, Hailiang|Dong, Xiaoqiang|Huang, Shiqian|Jin, Min|Ge, Hailiang|Xu, Congfeng|Zhang, Yanyun
PMID: 27203674
Journal: Am J Transl Res. 2016 Feb 15;8(2):1190-6. eCollection 2016.
Title: Colorectal cancer cells are resistant to anti-EGFR monoclonal antibody through adapted autophagy.
Author: Chen, Zhi|Gao, Shuohui|Wang, Dayv|Song, Defeng|Feng, Ye
PMID: 27158405
Journal: Int Immunopharmacol. 2016 Jun;35:248-256.
Title: Expression patterns of sirtuin 1-AMPK-autophagy pathway in chronic colitis and inflammation-associated colon neoplasia in IL-10-deficient mice.
Author: Talero, Elena|Alcaide, Antonio|Avila-Roman, Javier|Garcia-Maurino, Sofia|Vendramini-Costa, Debora|Motilva, Virginia
PMID: 27085036
Journal: Tumour Biol. 2016 Sep;37(9):11743-11752.
Title: Autophagy inhibition sensitizes WYE-354-induced anti-colon cancer activity in vitro and in vivo.
Author: Wang, Lijun|Zhu, Yun-Rong|Wang, Shaowei|Zhao, Song
PMID: 27020593
Journal: Int J Mol Med. 2016 Apr;37(4):1030-8.
Title: miR-409-3p sensitizes colon cancer cells to oxaliplatin by inhibiting Beclin-1-mediated autophagy.
Author: Tan, Shifan|Shi, Huijuan|Ba, Mingchen|Lin, Shengqv|Tang, Hongsheng|Zeng, Xiaoqi|Zhang, Xiangliang
PMID: 26935807
Journal: Mol Med Rep. 2016 Mar;13(3):2661-70.
Title: Effects of autophagy regulation of tumor-associated macrophages on radiosensitivity of colorectal cancer cells.
Author: Shao, Le-Ning|Zhu, Bao-Song|Xing, Chun-Gen|Yang, Xiao-Dong|Young, Wu|Cao, Jian-Ping
PMID: 26821367
Journal: Oncotarget. 2016 Feb 23;7(8):9188-221.
Title: BRAF associated autophagy exploitation: BRAF and autophagy inhibitors synergise to efficiently overcome resistance of BRAF mutant colorectal cancer cells.
Author: Goulielmaki, Maria|Koustas, Evangelos|Moysidou, Eirini|Vlassi, Margarita|Sasazuki, Takehiko|Shirasawa, Senji|Zografos, George|Oikonomou, Eftychia|Pintzas, Alexander
PMID: 26802026
Journal: Biosci Trends. 2017 May 23;11(2):221-228.
Title: Role of the pretreatment (18)F-fluorodeoxyglucose positron emission tomography maximal standardized uptake value in predicting outcomes of colon liver metastases and that value's association with Beclin-1 expression.
Author: Dimitrova, Eleonora G|Chaushev, Borislav G|Conev, Nikolay V|Kashlov, Javor K|Zlatarov, Aleksandar K|Petrov, Dilyan P|Popov, Hristo B|Stefanova, Nadezhda T|Klisarova, Anelia D|Bratoeva, Kameliya Z|Donev, Ivan S
PMID: 28250335
Journal: Biomed Res Int. 2017;2017:7203584.
Title: Zoledronic Acid Regulates Autophagy and Induces Apoptosis in Colon Cancer Cell Line CT26.
Author: Zhu, Jinhua|Liu, Meihui|Liu, Yuanfen|Zhang, Yiting|Yang, Bing|Zhang, Wei
PMID: 29457036
Journal: J Exp Clin Cancer Res. 2017 Dec 22;36(1):190.
Title: Curcumin synergizes with 5-fluorouracil by impairing AMPK/ULK1-dependent autophagy, AKT activity and enhancing apoptosis in colon cancer cells with tumor growth inhibition in xenograft mice.
Author: Zhang, Pan|Lai, Ze-Lin|Chen, Hui-Fen|Zhang, Min|Wang, An|Jia, Tao|Sun, Wen-Qin|Zhu, Xi-Min|Chen, Xiao-Feng|Zhao, Zheng|Zhang, Jun
PMID: 29273065
Journal: Oncotarget. 2017 Aug 2;8(59):99451-99469.
Title: Curcumin interacts with sildenafil to kill GI tumor cells via endoplasmic reticulum stress and reactive oxygen/ nitrogen species.
Author: Roberts, Jane L|Poklepovic, Andrew|Booth, Laurence
PMID: 29245915
Journal: Oncotarget. 2017 Aug 19;8(43):74781-74790.
Title: Beclin 1 acetylation impairs the anticancer effect of aspirin in colorectal cancer cells.
Author: Sun, Ting|Ming, Liang|Yan, Yunmeng|Zhang, Yan|Xue, Haikuo
PMID: 29088823
Journal: Sci Rep. 2017 Oct 24;7(1):13912.
Title: Phosphoinositide-specific phospholipase Cgamma1 inhibition induces autophagy in human colon cancer and hepatocellular carcinoma cells.
Author: Dai, Lianzhi|Chen, Xiaolei|Lu, Xiaohong|Wang, Fen|Zhan, Yanyan|Song, Gang|Hu, Tianhui|Xia, Chun|Zhang, Bing
PMID: 29066806
Journal: PLoS One. 2017 Oct 24;12(10):e0184501.
Title: The preclinical analysis of TW-37 as a potential anti-colorectal cancer cell agent.
Author: Lei, Shun|Ding, Yao|Fu, Yun|Wu, Shuang|Xie, Xiong|Wang, Cancan|Liang, Houjie
PMID: 29065135
Journal: Tumour Biol. 2017 Jun;39(6):1010428317703984.
Title: Mir-30d suppresses cell proliferation of colon cancer cells by inhibiting cell autophagy and promoting cell apoptosis.
Author: Zhang, Rui|Xu, Jian|Zhao, Jian|Bai, Jinghui
PMID: 28651493
Journal: Oncol Rep. 2017 Jul;38(1):31-42.
Title: Synthetic lethal interaction of CDK inhibition and autophagy inhibition in human solid cancer cell lines.
Author: Okada, Yoshinari|Kato, Shunsuke|Sakamoto, Yasuhiro|Oishi, Takayuki|Ishioka, Chikashi
PMID: 28560460
Journal: Oncotarget. 2017 Feb 28;8(9):14736-14747.
Title: AMPK-autophagy inhibition sensitizes icaritin-induced anti-colorectal cancer cell activity.
Author: Zhou, Chunxian|Gu, Jun|Zhang, Gang|Dong, Da|Yang, Qunying|Chen, Min-Bin|Xu, Dongfeng
PMID: 28103582
Journal: Med Oncol. 2017 Feb;34(2):16.
Title: The BAX gene as a candidate for negative autophagy-related genes regulator on mRNA levels in colorectal cancer.
Author: Gil, Justyna|Ramsey, David|Szmida, Elzbieta|Leszczynski, Przemyslaw|Pawlowski, Pawel|Bebenek, Marek|Sasiadek, Maria M
PMID: 28035578
Journal: Biomol Ther (Seoul). 2017 May 1;25(3):315-320.
Title: Reduced Autophagy in 5-Fluorouracil Resistant Colon Cancer Cells.
Author: Yao, Cheng Wen|Kang, Kyoung Ah|Piao, Mei Jing|Ryu, Yea Seong|Fernando, Pattage Madushan Dilhara Jayatissa|Oh, Min Chang|Park, Jeong Eon|Shilnikova, Kristina|Na, Soo-Young|Jeong, Seung Uk|Boo, Sun-Jin|Hyun, Jin Won
PMID: 27737524
Journal: Oncotarget. 2017 Aug 4;8(35):59058-59067.
Title: Beclin 1 and LC3 as predictive biomarkers for metastatic colorectal carcinoma.
Author: Zhao, Hong|Yang, Maopeng|Zhao, Bin
PMID: 28938618
Journal: Nutrients. 2018 Oct 12;10(10). pii: nu10101490.
Title: Sicilian Litchi Fruit Extracts Induce Autophagy versus Apoptosis Switch in Human Colon Cancer Cells.
Author: Emanuele, Sonia|Notaro, Antonietta|Palumbo Piccionello, Antonio|Maggio, Antonella|Lauricella, Marianna|D'Anneo, Antonella|Cernigliaro, Cesare|Calvaruso, Giuseppe|Giuliano, Michela
PMID: 30322062
Journal: J Cell Physiol. 2018 Sep 10.
Title: Neratinib augments the lethality of [regorafenib + sildenafil].
Author: Booth, Laurence|Roberts, Jane L|Rais, Rumeesa|Cutler, Richard E Jr|Diala, Irmina|Lalani, Alshad S|Hancock, John F|Poklepovic, Andrew|Dent, Paul
PMID: 30203445
Journal: PLoS One. 2018 Aug 27;13(8):e0202856.
Title: Opposite functions of GSN and OAS2 on colorectal cancer metastasis, mediating perineural and lymphovascular invasion, respectively.
Author: Kim, Jin Cheon|Ha, Ye Jin|Tak, Ka Hee|Roh, Seon Ae|Kwon, Yi Hong|Kim, Chan Wook|Yoon, Yong Sik|Lee, Jong Lyul|Park, Yangsoon|Kim, Seon-Kyu|Kim, Seon-Young|Cho, Dong-Hyung|Kim, Yong Sung
PMID: 30148861
Journal: Biomater Sci. 2018 Aug 21;6(9):2508-2517.
Title: Autophagy is an important action mode for functionalized selenium nanoparticles to exhibit anti-colorectal cancer activity.
Author: Huang, Guanning|Liu, Zumei|He, Lizhen|Luk, Kar-Him|Cheung, Siu-To|Wong, Ka-Hing|Chen, Tianfeng
PMID: 30091749
Journal: Discov Med. 2018 Jun;25(140):265-275.
Title: miR-212 and mTOR form a regulation loop to modulate autophagy in colorectal adenoma HT-29 cells.
Author: Ji, Changxue|Ju, Shuai|Qiang, Jinwei
PMID: 30021100
Journal: Int J Mol Med. 2018 Sep;42(3):1295-1304.
Title: Artesunate induces apoptosis and autophagy in HCT116 colon cancer cells, and autophagy inhibition enhances the artesunateinduced apoptosis.
Author: Jiang, Feng|Zhou, Jin-Yong|Zhang, Dan|Liu, Ming-Hao|Chen, Yu-Gen
PMID: 29901098
Journal: Ann Gastroenterol Surg. 2018 Jan 11;2(2):154-161.
Title: Blue light-emitting diodes induce autophagy in colon cancer cells by Opsin 3.
Author: Yoshimoto, Toshiaki|Morine, Yuji|Takasu, Chie|Feng, Rui|Ikemoto, Tetsuya|Yoshikawa, Kozo|Iwahashi, Syuichi|Saito, Yu|Kashihara, Hideya|Akutagawa, Masatake|Emoto, Takahiro|Kinouchi, Yosuke|Shimada, Mitsuo
PMID: 29863164
Journal: J Cell Biochem. 2018 Aug;119(8):7022-7031.
Title: Knockdown of Beclin-1 impairs epithelial-mesenchymal transition of colon cancer cells.
Author: Shen, Hong|Yin, Ling|Deng, Ganlu|Guo, Cao|Han, Ying|Li, Yiyi|Cai, Changjing|Fu, Yaojie|Liu, Shanshan|Zeng, Shan
PMID: 29738069
Journal: Mol Cancer Res. 2018 Jul;16(7):1077-1091.
Title: Crosstalk Between Apoptosis and Autophagy Is Regulated by the Arginylated BiP/Beclin-1/p62 Complex.
Author: Song, Xinxin|Lee, Dae-Hee|Dilly, Ashok-Kumar|Lee, Young-Sun|Choudry, Haroon Asif|Kwon, Yong Tae|Bartlett, David L|Lee, Yong J
PMID: 29669822
Journal: Cell Oncol (Dordr). 2018 Jun;41(3):297-317.
Title: Inhibition of autophagy enhances DENSpm-induced apoptosis in human colon cancer cells in a p53 independent manner.
Author: Gurkan, Ajda Coker|Arisan, Elif Damla|Yerlikaya, Pinar Obakan|Ilhan, Halime|Unsal, Narcin Palavan
PMID: 29492901
Journal: Photodiagnosis Photodyn Ther. 2018 Mar;21:396-403.
Title: Inhibition of autophagy potentiates the apoptosis-inducing effects of photodynamic therapy on human colon cancer cells.
Author: Ouyang, Guoqing|Xiong, Li|Liu, Zhipeng|Lam, Brandon|Bui, Brian|Ma, Lun|Chen, Xiang|Zhou, Pan|Wang, Kunpeng|Zhang, Zijian|Huang, He|Miao, Xiongying|Chen, Wei|Wen, Yu
PMID: 29355734
Journal: Int J Mol Med. 2018 Mar;41(3):1305-1314.
Title: Codonopis bulleynana Forest ex Diels inhibits autophagy and induces apoptosis of colon cancer cells by activating the NF-kappaB signaling pathway.
Author: Luan, Yunpeng|Li, Yanmei|Zhu, Lina|Zheng, Shuangqing|Mao, Dechang|Chen, Zhuxue|Cao, Yong
PMID: 29286074
Journal: J Cell Biochem. 2018 Apr;119(4):3763-3774.
Title: Hyperthermia enhances radiosensitivity of colorectal cancer cells through ROS inducing autophagic cell death.
Author: Ba, Ming-Chen|Long, Hui|Wang, Shuai|Wu, Yin-Bing|Zhang, Bo-Huo|Yan, Zhao-Fei|Yu, Fei-Hong|Cui, Shu-Zhong
PMID: 29240246
Journal: Toxicol In Vitro. 2018 Mar;47:129-136.
Title: In vitro antitumor effect of a lignan isolated from Combretum fruticosum, trachelogenin, in HCT-116 human colon cancer cells.
Author: Moura, A F|Lima, K S B|Sousa, T S|Marinho-Filho, J D B|Pessoa, C|Silveira, E R|Pessoa, O D L|Costa-Lotufo, L V|Moraes, M O|Araujo, A J
PMID: 29174024
Journal: J Cell Physiol. 2018 Jan;233(1):497-505.
Title: Autophagy mediates cytotoxicity of human colorectal cancer cells treated with garcinielliptone FC.
Author: Won, Shen-Jeu|Yen, Cheng-Hsin|Lin, Ting-Yu|Jiang-Shieh, Ya-Fen|Lin, Chun-Nan|Chen, Jyun-Ti|Su, Chun-Li
PMID: 28294332