Primary Site >> Colorectal Cancer
Gene >> BCL2L11
| 1. | |||||||||||
| Journal: | Mol Cancer Ther. 2005 Mar;4(3):443-9. | ||||||||||
| Title: | The proteasome inhibitor bortezomib sensitizes cells to killing by death receptor ligand TRAIL via BH3-only proteins Bik and Bim. | ||||||||||
| Author: | Nikrad, Malti|Johnson, Thomas|Puthalalath, Hamsa|Coultas, Leigh|Adams, Jerry|Kraft, Andrew S | ||||||||||
| PMID: | 15767553 | ||||||||||
| 2. | |||||||||||
| Journal: | Oncogene. 2008 Dec 4;27(57):7192-200. | ||||||||||
| Title: | Therapeutic targeting of Id2 reduces growth of human colorectal carcinoma in the murine liver. | ||||||||||
| Author: | Gray, M J|Dallas, N A|Van Buren, G|Xia, L|Yang, A D|Somcio, R J|Gaur, P|Mangala, L S|Vivas-Mejia, P E|Fan, F|Sanguino, A M|Gallick, G E|Lopez-Berestein, G|Sood, A K|Ellis, L M | ||||||||||
| PMID: | 18806828 | ||||||||||
| 3. | |||||||||||
| Journal: | Clin Cancer Res. 2008 Dec 15;14(24):8132-42. | ||||||||||
| Title: | Induction of Noxa sensitizes human colorectal cancer cells expressing Mcl-1 to the small-molecule Bcl-2/Bcl-xL inhibitor, ABT-737. | ||||||||||
| Author: | Okumura, Kenji|Huang, Shengbing|Sinicrope, Frank A | ||||||||||
| PMID: | 19088028 | ||||||||||
| 4. | |||||||||||
| Journal: | Mol Cancer Ther. 2009 Feb;8(2):342-9. | ||||||||||
| Title: | Vorinostat and bortezomib exert synergistic antiproliferative and proapoptotic effects in colon cancer cell models. | ||||||||||
| Author: | Pitts, Todd M|Morrow, Mark|Kaufman, Sara A|Tentler, John J|Eckhardt, S Gail | ||||||||||
| PMID: | 19174560 | ||||||||||
| 5. | |||||||||||
| Journal: | IUBMB Life. 2009 Jul;61(7):768-76. | ||||||||||
| Title: | Relative resistance of SGK1 knockout mice against chemical carcinogenesis. | ||||||||||
| Author: | Nasir, Omaima|Wang, Kan|Foller, Michael|Gu, Shuchen|Bhandaru, Madhuri|Ackermann, Teresa F|Boini, Krishna M|Mack, Andreas|Klingel, Karin|Amato, Rosario|Perrotti, Nicola|Kuhl, Dietmar|Behrens, Jurgen|Stournaras, Christos|Lang, Florian | ||||||||||
| PMID: | 19548318 | ||||||||||
| 6. | |||||||||||
| Journal: | Pathobiology. 2009;76(4):163-9. | ||||||||||
| Title: | RUNX3 inhibits cell proliferation and induces apoptosis by TGF-beta-dependent and -independent mechanisms in human colon carcinoma cells. | ||||||||||
| Author: | Tong, Dan-Dan|Jiang, Ying|Li, Ming|Kong, Dan|Meng, Xiang-Nin|Zhao, Yu-Zhen|Jin, Yan|Bai, Jing|Fu, Song-Bin|Geng, Jing-Shu | ||||||||||
| PMID: | 19571605 | ||||||||||
| 7. | |||||||||||
| Journal: | Cancer Res. 2009 Aug 1;69(15):6115-21. | ||||||||||
| Title: | Differentiation-related gene-1 decreases Bim stability by proteasome-mediated degradation. | ||||||||||
| Author: | Ambrosini, Grazia|Seelman, Sharon L|Schwartz, Gary K | ||||||||||
| PMID: | 19622774 | ||||||||||
| 8. | |||||||||||
| Journal: | Oncogene. 2009 Dec 17;28(50):4421-33. | ||||||||||
| Title: | A novel pro-apoptotic function of RACK1: suppression of Src activity in the intrinsic and Akt pathways. | ||||||||||
| Author: | Mamidipudi, V|Cartwright, C A | ||||||||||
| PMID: | 19767770 | ||||||||||
| 9. | |||||||||||
| Journal: | Oncogene. 2010 Jun 10;29(23):3398-410. | ||||||||||
| Title: | The proapoptotic BH3-only protein Bim is downregulated in a subset of colorectal cancers and is repressed by antiapoptotic COX-2/PGE(2) signalling in colorectal adenoma cells. | ||||||||||
| Author: | Greenhough, A|Wallam, C A|Hicks, D J|Moorghen, M|Williams, A C|Paraskeva, C | ||||||||||
| PMID: | 20348947 | ||||||||||
| 10. | |||||||||||
| Journal: | PLoS One. 2010 Sep 22;5(9):e12895. | ||||||||||
| Title: | CXCL12 chemokine expression and secretion regulates colorectal carcinoma cell anoikis through Bim-mediated intrinsic apoptosis. | ||||||||||
| Author: | Drury, Luke J|Wendt, Michael K|Dwinell, Michael B | ||||||||||
| PMID: | 20877573 | ||||||||||
| 11. | |||||||||||
| Journal: | J Biol Chem. 2011 May 6;286(18):16082-90. | ||||||||||
| Title: | Restoration of transforming growth factor-beta receptor II expression in colon cancer cells with microsatellite instability increases metastatic potential in vivo. | ||||||||||
| Author: | Liu, Xiao-Qiong|Rajput, Ashwani|Geng, Liying|Ongchin, Melanie|Chaudhuri, Anathbandhu|Wang, Jing | ||||||||||
| PMID: | 21454688 | ||||||||||
| 12. | |||||||||||
| Journal: | Cancer Sci. 2011 Dec;102(12):2264-71. | ||||||||||
| Title: | miR-92 is a key oncogenic component of the miR-17-92 cluster in colon cancer. | ||||||||||
| Author: | Tsuchida, Akihiko|Ohno, Shinichiro|Wu, Weihong|Borjigin, Nariso|Fujita, Koji|Aoki, Tastuya|Ueda, Shinobu|Takanashi, Masakatsu|Kuroda, Masahiko | ||||||||||
| PMID: | 21883694 | ||||||||||
| 13. | |||||||||||
| Journal: | Cancer Res. 2012 Apr 1;72(7):1804-13. | ||||||||||
| Title: | Enhanced apoptosis and tumor growth suppression elicited by combination of MEK (selumetinib) and mTOR kinase inhibitors (AZD8055). | ||||||||||
| Author: | Holt, Sarah V|Logie, Armelle|Davies, Barry R|Alferez, Denis|Runswick, Sarah|Fenton, Sarah|Chresta, Christine M|Gu, Yi|Zhang, Jingchuan|Wu, Yi-Long|Wilkinson, Robert W|Guichard, Sylvie M|Smith, Paul D | ||||||||||
| PMID: | 22271687 | ||||||||||
| 14. | |||||||||||
| Journal: | J Cell Sci. 2012 Feb 15;125(Pt 4):887-95. | ||||||||||
| Title: | The microtubule poison vinorelbine kills cells independently of mitotic arrest and targets cells lacking the APC tumour suppressor more effectively. | ||||||||||
| Author: | Klotz, Daniel M|Nelson, Scott A|Kroboth, Karin|Newton, Ian P|Radulescu, Sorina|Ridgway, Rachel A|Sansom, Owen J|Appleton, Paul L|Nathke, Inke S | ||||||||||
| PMID: | 22399804 | ||||||||||
| 15. | |||||||||||
| Journal: | Ann Surg Oncol. 2012 Sep;19(9):3065-71. | ||||||||||
| Title: | MicroRNA-10b is a prognostic indicator in colorectal cancer and confers resistance to the chemotherapeutic agent 5-fluorouracil in colorectal cancer cells. | ||||||||||
| Author: | Nishida, Naohiro|Yamashita, Shinya|Mimori, Koshi|Sudo, Tomoya|Tanaka, Fumiaki|Shibata, Kohei|Yamamoto, Hirofumi|Ishii, Hideshi|Doki, Yuichiro|Mori, Masaki | ||||||||||
| PMID: | 22322955 | ||||||||||
| 16. | |||||||||||
| Journal: | Mol Carcinog. 2013 Jun;52(6):459-74. | ||||||||||
| Title: | Histone deacetylase inhibition in colorectal cancer cells reveals competing roles for members of the oncogenic miR-17-92 cluster. | ||||||||||
| Author: | Humphreys, Karen J|Cobiac, Lynne|Le Leu, Richard K|Van der Hoek, Mark B|Michael, Michael Z | ||||||||||
| PMID: | 22308110 | ||||||||||
| 17. | |||||||||||
| Journal: | Biochem J. 2013 Mar 1;450(2):285-94. | ||||||||||
| Title: | The BH3 mimetic ABT-263 synergizes with the MEK1/2 inhibitor selumetinib/AZD6244 to promote BIM-dependent tumour cell death and inhibit acquired resistance. | ||||||||||
| Author: | Sale, Matthew J|Cook, Simon J | ||||||||||
| PMID: | 23234544 | ||||||||||
| 18. | |||||||||||
| Journal: | PLoS One. 2013;8(2):e56369. | ||||||||||
| Title: | Pramanicin analog induces apoptosis in human colon cancer cells: critical roles for Bcl-2, Bim, and p38 MAPK signaling. | ||||||||||
| Author: | Bodur, Cagri|Kutuk, Ozgur|Karsli-Uzunbas, Gizem|Isimjan, Tayirjan T|Harrison, Paul|Basaga, Huveyda | ||||||||||
| PMID: | 23441183 | ||||||||||
| 19. | |||||||||||
| Journal: | Zhonghua Wei Chang Wai Ke Za Zhi. 2013 Jun;16(6):538-42. | ||||||||||
| Title: | [Role of BH3-only gene in the oxaliplatin-induced apoptosis of colon cancer cells]. | ||||||||||
| Author: | Tu, Shi-liang|Yuan, Hang|He, Xu-jun|Ma, Ying-yu | ||||||||||
| PMID: | 23801206 | ||||||||||
| 20. | |||||||||||
| Journal: | Med Oncol. 2013 Dec;30(4):704. | ||||||||||
| Title: | The effects of silencing of PI3K p85alpha on 5-FU-induced colorectal cancer cells apoptosis. | ||||||||||
| Author: | Sun, Yan|Tian, Hua|Wang, Lin|Yang, Hui | ||||||||||
| PMID: | 23990352 | ||||||||||
| 21. | |||||||||||
| Journal: | Zhonghua Wai Ke Za Zhi. 2013 Jun 1;51(6):547-51. | ||||||||||
| Title: | [Relationship between PUMA and BIM expression in colorectal cancer and tumor invasion, metastasis and prognosis]. | ||||||||||
| Author: | Yuan, Hang|Tu, Shi-Liang|He, Xu-Jun | ||||||||||
| PMID: | 24091272 | ||||||||||
| 22. | |||||||||||
| Journal: | Cancer Discov. 2014 Jan;4(1):42-52. | ||||||||||
| Title: | mTOR inhibition specifically sensitizes colorectal cancers with KRAS or BRAF mutations to BCL-2/BCL-XL inhibition by suppressing MCL-1. | ||||||||||
| Author: | Faber, Anthony C|Coffee, Erin M|Costa, Carlotta|Dastur, Anahita|Ebi, Hiromichi|Hata, Aaron N|Yeo, Alan T|Edelman, Elena J|Song, Youngchul|Tam, Ah Ting|Boisvert, Jessica L|Milano, Randy J|Roper, Jatin|Kodack, David P|Jain, Rakesh K|Corcoran, Ryan B|Rivera, | ||||||||||
| PMID: | 24163374 | ||||||||||
| 23. | |||||||||||
| Journal: | Exp Ther Med. 2014 Nov;8(5):1494-1500. | ||||||||||
| Title: | Activation of the apoptosis signal-regulating kinase 1/c-Jun N-terminal kinase pathway is involved in the casticin-induced apoptosis of colon cancer cells. | ||||||||||
| Author: | Qu, Lin|Liu, Feng-Xia|Cao, Xiao-Cheng|Xiao, Qiao|Yang, Xiaohong|Ren, Kai-Qun | ||||||||||
| PMID: | 25289048 | ||||||||||
| 24. | |||||||||||
| Journal: | Proc Natl Acad Sci U S A. 2014 May 27;111(21):E2229-36. | ||||||||||
| Title: | Oncogenic mutations in intestinal adenomas regulate Bim-mediated apoptosis induced by TGF-beta. | ||||||||||
| Author: | Wiener, Zoltan|Band, Arja M|Kallio, Pauliina|Hogstrom, Jenny|Hyvonen, Ville|Kaijalainen, Seppo|Ritvos, Olli|Haglund, Caj|Kruuna, Olli|Robine, Sylvie|Louvard, Daniel|Ben-Neriah, Yinon|Alitalo, Kari | ||||||||||
| PMID: | 24825889 | ||||||||||
| 25. | |||||||||||
| Journal: | Exp Biol Med (Maywood). 2014 Mar;239(3):302-10. | ||||||||||
| Title: | Colon cancer cell apoptosis is induced by combined exposure to the n-3 fatty acid docosahexaenoic acid and butyrate through promoter methylation. | ||||||||||
| Author: | Cho, Youngmi|Turner, Nancy D|Davidson, Laurie A|Chapkin, Robert S|Carroll, Raymond J|Lupton, Joanne R | ||||||||||
| PMID: | 24495951 | ||||||||||
| 26. | |||||||||||
| Journal: | Cancer Lett. 2014 Mar 1;344(1):110-8. | ||||||||||
| Title: | Targeted therapy against chemoresistant colorectal cancers: Inhibition of p38alpha modulates the effect of cisplatin in vitro and in vivo through the tumor suppressor FoxO3A. | ||||||||||
| Author: | Germani, Aldo|Matrone, Antonio|Grossi, Valentina|Peserico, Alessia|Sanese, Paola|Liuzzi, Micaela|Palermo, Rocco|Murzilli, Stefania|Campese, Antonio Francesco|Ingravallo, Giuseppe|Canettieri, Gianluca|Tezil, Tugsan|Simone, Cristiano | ||||||||||
| PMID: | 24215867 | ||||||||||
| 27. | |||||||||||
| Journal: | Cell Rep. 2014 Apr 10;7(1):86-93. | ||||||||||
| Title: | Intrinsic resistance to MEK inhibition in KRAS mutant lung and colon cancer through transcriptional induction of ERBB3. | ||||||||||
| Author: | Sun, Chong|Hobor, Sebastijan|Bertotti, Andrea|Zecchin, Davide|Huang, Sidong|Galimi, Francesco|Cottino, Francesca|Prahallad, Anirudh|Grernrum, Wipawadee|Tzani, Anna|Schlicker, Andreas|Wessels, Lodewyk F A|Smit, Egbert F|Thunnissen, Erik|Halonen, Pasi|Lieft | ||||||||||
| PMID: | 24685132 | ||||||||||
| 28. | |||||||||||
| Journal: | Lipids. 2015 Mar;50(3):227-39. | ||||||||||
| Title: | miRNA expression in human intestinal Caco-2 cells is comparably regulated by cis- and trans-fatty acids. | ||||||||||
| Author: | Kopke, Solveigh|Buhrke, Thorsten|Lampen, Alfonso | ||||||||||
| PMID: | 25612549 | ||||||||||
| 29. | |||||||||||
| Journal: | J Biol Chem. 2015 Sep 25;290(39):23838-49. | ||||||||||
| Title: | The Mutant KRAS Gene Up-regulates BCL-XL Protein via STAT3 to Confer Apoptosis Resistance That Is Reversed by BIM Protein Induction and BCL-XL Antagonism. | ||||||||||
| Author: | Zaanan, Aziz|Okamoto, Koichi|Kawakami, Hisato|Khazaie, Khashayarsha|Huang, Shengbing|Sinicrope, Frank A | ||||||||||
| PMID: | 26245900 | ||||||||||
| 30. | |||||||||||
| Journal: | Toxicol Lett. 2016 Aug 22;257:84-96. | ||||||||||
| Title: | Isoledene from Mesua ferrea oleo-gum resin induces apoptosis in HCT 116 cells through ROS-mediated modulation of multiple proteins in the apoptotic pathways: A mechanistic study. | ||||||||||
| Author: | Asif, Muhammad|Shafaei, Armaghan|Jafari, Seyedeh Fatemeh|Mohamed, Shazmin Kithur|Ezzat, Mohammed Oday|Abdul Majid, Aman Shah|Oon, Chern Ein|Petersen, Sven H|Kono, Koji|Abdul Majid, Amin Malik Shah | ||||||||||
| PMID: | 27268964 | ||||||||||
| 31. | |||||||||||
| Journal: | Oncol Rep. 2016 Aug;36(2):1119-26. | ||||||||||
| Title: | Butyrate-mediated acquisition of chemoresistance by human colon cancer cells. | ||||||||||
| Author: | Kang, Hyang Ri|Choi, Hyeon Gyeom|Jeon, Chae Kyung|Lim, Soo-Jeong|Kim, So Hee | ||||||||||
| PMID: | 27277338 | ||||||||||
| 32. | |||||||||||
| Journal: | Biomol Ther (Seoul). 2016 May 1;24(3):320-7. | ||||||||||
| Title: | Columbianadin Inhibits Cell Proliferation by Inducing Apoptosis and Necroptosis in HCT116 Colon Cancer Cells. | ||||||||||
| Author: | Kang, Ji In|Hong, Ji-Young|Choi, Jae Sue|Lee, Sang Kook | ||||||||||
| PMID: | 27098859 | ||||||||||
| 33. | |||||||||||
| Journal: | Chem Biol Interact. 2016 Apr 5;249:23-35. | ||||||||||
| Title: | In vitro antiproliferative activity of 2,3-dihydroxy-9,10-anthraquinone induced apoptosis against COLO320 cells through cytochrome c release caspase mediated pathway with PI3K/AKT and COX-2 inhibition. | ||||||||||
| Author: | Balachandran, C|Emi, N|Arun, Y|Yamamoto, N|Duraipandiyan, V|Inaguma, Yoko|Okamoto, Akinao|Ignacimuthu, S|Al-Dhabi, N A|Perumal, P T | ||||||||||
| PMID: | 26915975 | ||||||||||
| 34. | |||||||||||
| Journal: | Eur J Med Chem. 2016 Mar 23;111:183-92. | ||||||||||
| Title: | Identification of a new cyathane diterpene that induces mitochondrial and autophagy-dependent apoptosis and shows a potent in vivo anti-colorectal cancer activity. | ||||||||||
| Author: | He, Luwei|Han, Junjie|Li, Baowei|Huang, Li|Ma, Ke|Chen, Quan|Liu, Xinzhong|Bao, Li|Liu, Hongwei | ||||||||||
| PMID: | 26871659 | ||||||||||
| 35. | |||||||||||
| Journal: | Mol Cancer Ther. 2016 Mar;15(3):448-59. | ||||||||||
| Title: | Inhibition of HSP90 by AUY922 Preferentially Kills Mutant KRAS Colon Cancer Cells by Activating Bim through ER Stress. | ||||||||||
| Author: | Wang, Chun Yan|Guo, Su Tang|Wang, Jia Yu|Liu, Fen|Zhang, Yuan Yuan|Yari, Hamed|Yan, Xu Guang|Jin, Lei|Zhang, Xu Dong|Jiang, Chen Chen | ||||||||||
| PMID: | 26832792 | ||||||||||
| 36. | |||||||||||
| Journal: | Gene. 2017 Sep 30;630:1-7. | ||||||||||
| Title: | DNA methylation of CMTM3, SSTR2, and MDFI genes in colorectal cancer. | ||||||||||
| Author: | Li, Jinyun|Chen, Cheng|Bi, Xuer|Zhou, Chongchang|Huang, Tao|Ni, Chao|Yang, Ping|Chen, Si|Ye, Meng|Duan, Shiwei | ||||||||||
| PMID: | 28782576 | ||||||||||
| 37. | |||||||||||
| Journal: | Oncol Lett. 2017 Dec;14(6):6571-6577. | ||||||||||
| Title: | Aurora kinase A inhibitor TCS7010 demonstrates pro-apoptotic effect through the unfolded protein response pathway in HCT116 colon cancer cells. | ||||||||||
| Author: | Lee, Da Hyun|Kim, Chang Gun|Lim, Yoongho|Shin, Soon Young | ||||||||||
| PMID: | 29163689 | ||||||||||
| 38. | |||||||||||
| Journal: | Biomed Pharmacother. 2018 Feb;98:286-296. | ||||||||||
| Title: | Knockdown of the long non-coding RNA HOTTIP inhibits colorectal cancer cell proliferation and migration and induces apoptosis by targeting SGK1. | ||||||||||
| Author: | Liu, Tianyou|Yu, Tao|Hu, Haiying|He, Keping | ||||||||||
| PMID: | 29274585 | ||||||||||
| 39. | |||||||||||
| Journal: | Molecules. 2018 Mar 22;23(4). pii: molecules23040723. | ||||||||||
| Title: | Food Additive Sodium Benzoate (NaB) Activates NFkappaB and Induces Apoptosis in HCT116 Cells. | ||||||||||
| Author: | Yilmaz, Betul|Karabay, Arzu Zeynep | ||||||||||
| PMID: | 29565269 | ||||||||||
| 40. | |||||||||||
| Journal: | Neoplasia. 2018 May;20(5):411-424. | ||||||||||
| Title: | POH1 Knockdown Induces Cancer Cell Apoptosis via p53 and Bim. | ||||||||||
| Author: | Wang, Chun-Hua|Lu, Shi-Xun|Liu, Li-Li|Li, Yong|Yang, Xia|He, Yang-Fan|Chen, Shi-Lu|Cai, Shao-Hang|Wang, Hong|Yun, Jing-Ping | ||||||||||
| PMID: | 29573636 | ||||||||||
| 41. | |||||||||||
| Journal: | Eur Rev Med Pharmacol Sci. 2018 Jun;22(12):3771-3778. | ||||||||||
| Title: | Effects of miR-223 on colorectal cancer cell proliferation and apoptosis through regulating FoxO3a/BIM. | ||||||||||
| Author: | Ju, H|Tan, J-Y|Cao, B|Song, M-Q|Tian, Z-B | ||||||||||
| PMID: | 29949152 | ||||||||||
| 42. | |||||||||||
| Journal: | Cell Physiol Biochem. 2018;48(4):1628-1637. | ||||||||||
| Title: | Knockdown of Mir-135b Sensitizes Colorectal Cancer Cells to Oxaliplatin-Induced Apoptosis Through Increase of FOXO1. | ||||||||||
| Author: | Qin, Yan|Li, Longhai|Wang, Fang|Zhou, Xinyi|Liu, Yankui|Yin, Yuan|Qi, Xiaowei | ||||||||||
| PMID: | 30071508 | ||||||||||