Primary Site >> Colorectal Cancer

Gene >> BCL2L1

Journal: Cancer Res. 1996 May 15;56(10):2422-7.
Title: Elevated expression of Bcl-X and reduced Bak in primary colorectal adenocarcinomas.
Author: Krajewska, M|Moss, S F|Krajewski, S|Song, K|Holt, P R|Reed, J C
PMID: 8625322
Journal: Oncogene. 1996 Dec 19;13(12):2631-7.
Title: Expression of wild-type p53 stimulates an increase in both Bax and Bcl-xL protein content in HT29 cells.
Author: Merchant, A K|Loney, T L|Maybaum, J
PMID: 9000137
Journal: EMBO J. 1996 Dec 16;15(24):6979-90.
Title: The cell death inhibitor Bcl-2 and its homologues influence control of cell cycle entry.
Author: O'Reilly, L A|Huang, D C|Strasser, A
PMID: 9003774
Journal: Mol Carcinog. 1997 May;19(1):25-30.
Title: Expression of bcl-2, bax, and bcl-XL proteins in azoxymethane-induced rat colonic adenocarcinomas.
Author: Hirose, Y|Yoshimi, N|Suzui, M|Kawabata, K|Tanaka, T|Mori, H
PMID: 9180925
Journal: Cancer Res. 1998 Jan 15;58(2):362-6.
Title: Modulation of apoptosis and Bcl-2 expression by prostaglandin E2 in human colon cancer cells.
Author: Sheng, H|Shao, J|Morrow, J D|Beauchamp, R D|DuBois, R N
PMID: 9443418
Journal: Br J Cancer. 1998 Oct;78(8):986-92.
Title: 5-Fluorouracil induces apoptosis in human colon cancer cell lines with modulation of Bcl-2 family proteins.
Author: Nita, M E|Nagawa, H|Tominaga, O|Tsuno, N|Fujii, S|Sasaki, S|Fu, C G|Takenoue, T|Tsuruo, T|Muto, T
PMID: 9792140
Journal: Clin Cancer Res. 1998 Nov;4(11):2841-8.
Title: Inhibition of apoptosis after thymineless stress is conferred by oncogenic K-Ras in colon carcinoma cells.
Author: Houghton, J A|Ebanks, R|Harwood, F G|Tillman, D M
PMID: 9829751
Journal: Dig Dis Sci. 1998 Dec;43(12):2641-8.
Title: Apoptosis inhibiting factor Bcl-xL might be the crucial member of the Bcl-2 gene family in colorectal cancer.
Author: Maurer, C A|Friess, H|Buhler, S S|Wahl, B R|Graber, H|Zimmermann, A|Buchler, M W
PMID: 9881495
Journal: Oncogene. 1998 Dec 10;17(23):2981-91.
Title: Expression of Bcl-XS alters cytokinetics and decreases clonogenic survival in K12 rat colon carcinoma cells.
Author: Fridman, J S|Rehemtulla, A|Hofmann, A|Blau, H M|Maybaum, J
PMID: 9881700
Journal: Jpn J Cancer Res. 1998 Nov;89(11):1169-78.
Title: A novel mutant from apoptosis-resistant colon cancer HT-29 cells showing hyper-apoptotic response to hypoxia, low glucose and cisplatin.
Author: Suzuki, H|Tomida, A|Tsuruo, T
PMID: 9914786
Journal: Cell Death Differ. 1998 Jun;5(6):480-7.
Title: Cancer cell sensitization to fas-mediated apoptosis by sodium butyrate.
Author: Bonnotte, B|Favre, N|Reveneau, S|Micheau, O|Droin, N|Garrido, C|Fontana, A|Chauffert, B|Solary, E|Martin, F
PMID: 10200499
Journal: Oncol Rep. 1999 Mar-Apr;6(2):365-9.
Title: Prognostic significance of Bcl-2, Bcl-xL/S, Bax and Bak expressions in colorectal carcinomas.
Author: Ogura, E|Senzaki, H|Yamamoto, D|Yoshida, R|Takada, H|Hioki, K|Tsubura, A
PMID: 10023006
Journal: Cancer Res. 2000 Apr 15;60(8):2304-12.
Title: Apoptosis is induced by the active metabolite of vitamin D3 and its analogue EB1089 in colorectal adenoma and carcinoma cells: possible implications for prevention and therapy.
Author: Diaz, G D|Paraskeva, C|Thomas, M G|Binderup, L|Hague, A
PMID: 10786699
Journal: Cancer Gene Ther. 2000 Apr;7(4):563-73.
Title: Two-drug combinations that increase apoptosis and modulate bak and bcl-X(L) expression in human colon tumor cell lines transduced with herpes simplex virus thymidine kinase.
Author: McMasters, R A|Wilbert, T N|Jones, K E|Pitlyk, K|Saylors, R L|Moyer, M P|Chambers, T C|Drake, R R
PMID: 10811474
Journal: Cancer Res. 2000 Jul 15;60(14):3823-31.
Title: Dietary flavone is a potent apoptosis inducer in human colon carcinoma cells.
Author: Wenzel, U|Kuntz, S|Brendel, M D|Daniel, H
PMID: 10919656
Journal: Br J Cancer. 2000 Sep;83(5):668-73.
Title: Met/HGF receptor modulates bcl-w expression and inhibits apoptosis in human colorectal cancers.
Author: Kitamura, S|Kondo, S|Shinomura, Y|Kanayama, S|Miyazaki, Y|Kiyohara, T|Hiraoka, S|Matsuzawa, Y
PMID: 10944610
Journal: Jpn J Cancer Res. 2000 Aug;91(8):825-32.
Title: Bcl-X(L) antisense sensitizes human colon cancer cell line to 5-fluorouracil.
Author: Nita, M E|Ono-Nita, S K|Tsuno, N|Tominaga, O|Takenoue, T|Sunami, E|Kitayama, J|Nakamura, Y|Nagawa, H
PMID: 10965024
Journal: Acta Oncol. 2000;39(4):495-500.
Title: Heterodimerization of Bcl-2 and Bcl-X(L) with Bax and Bad in colorectal cancer.
Author: Hattori, T|Ookawa, N|Fujita, R|Fukuchi, K
PMID: 11041112
Journal: Science. 2000 Nov 3;290(5493):989-92.
Title: Role of BAX in the apoptotic response to anticancer agents.
Author: Zhang, L|Yu, J|Park, B H|Kinzler, K W|Vogelstein, B
PMID: 11062132
Journal: Biochem Pharmacol. 2000 Dec 1;60(11):1579-84.
Title: Caspase-8 activation independent of CD95/CD95-L interaction during paclitaxel-induced apoptosis in human colon cancer cells (HT29-D4).
Author: Goncalves, A|Braguer, D|Carles, G|Andre, N|Prevot, C|Briand, C
PMID: 11077039
Journal: J Natl Cancer Inst. 2001 Mar 21;93(6):463-71.
Title: Activity of a novel bcl-2/bcl-xL-bispecific antisense oligonucleotide against tumors of diverse histologic origins.
Author: Gautschi, O|Tschopp, S|Olie, R A|Leech, S H|Simoes-Wust, A P|Ziegler, A|Baumann, B|Odermatt, B|Hall, J|Stahel, R A|Zangemeister-Wittke, U
PMID: 11259472
Journal: Am J Pathol. 2001 Apr;158(4):1289-99.
Title: c-Myb and Bcl-x overexpression predicts poor prognosis in colorectal cancer: clinical and experimental findings.
Author: Biroccio, A|Benassi, B|D'Agnano, I|D'Angelo, C|Buglioni, S|Mottolese, M|Ricciotti, A|Citro, G|Cosimelli, M|Ramsay, R G|Calabretta, B|Zupi, G
PMID: 11290547
Journal: Ann Oncol. 2001 Feb;12(2):209-16.
Title: 5-Fluorouracil induced Fas upregulation associated with apoptosis in liver metastases of colorectal cancer patients.
Author: Backus, H H|Dukers, D F|van Groeningen, C J|Vos, W|Bloemena, E|Wouters, D|van Riel, J M|Smid, K|Giaccone, G|Pinedo, H M|Peters, G J
PMID: 11300326
Journal: Anticancer Res. 2001 Mar-Apr;21(2A):873-8.
Title: Curcumin induced modulation of cell cycle and apoptosis in gastric and colon cancer cells.
Author: Moragoda, L|Jaszewski, R|Majumdar, A P
PMID: 11396178
Journal: Exp Cell Res. 2001 Aug 15;268(2):139-49.
Title: Autophagy delays sulindac sulfide-induced apoptosis in the human intestinal colon cancer cell line HT-29.
Author: Bauvy, C|Gane, P|Arico, S|Codogno, P|Ogier-Denis, E
PMID: 11478840
Journal: Ann Oncol. 2001 Jun;12(6):779-85.
Title: Rb, mcl-1 and p53 expression correlate with clinical outcome in patients with liver metastases from colorectal cancer.
Author: Backus, H H|van Riel, J M|van Groeningen, C J|Vos, W|Dukers, D F|Bloemena, E|Wouters, D|Pinedo, H M|Peters, G J
PMID: 11484952
Journal: J Biol Chem. 2001 Oct 12;276(41):37879-86.
Title: Identification of inhibitors of TRAIL-induced death (ITIDs) in the TRAIL-sensitive colon carcinoma cell line SW480 using a genetic approach.
Author: Burns, T F|El-Deiry, W S
PMID: 11486001
Journal: J Biol Chem. 2001 Oct 5;276(40):37273-9. Epub 2001 Aug 3.
Title: Transforming growth factor-alpha prevents detachment-induced inhibition of c-Src kinase activity, Bcl-XL down-regulation, and apoptosis of intestinal epithelial cells.
Author: Rosen, K|Coll, M L|Li, A|Filmus, J
PMID: 11487584
Journal: J Cell Biol. 2001 Aug 6;154(3):573-84.
Title: Expression of alpha-catenin in alpha-catenin-deficient cells increases resistance to sphingosine-induced apoptosis.
Author: Matsubara, S|Ozawa, M
PMID: 11489917
Journal: Mech Ageing Dev. 2001 Oct;122(15):1849-64.
Title: Aging is associated with increased proliferation and decreased apoptosis in the colonic mucosa.
Author: Xiao, Z Q|Moragoda, L|Jaszewski, R|Hatfield, J A|Fligiel, S E|Majumdar, A P
PMID: 11557285
Journal: Cancer Chemother Pharmacol. 2001 Sep;48(3):188-96.
Title: Synergistic interaction between topotecan and microtubule-interfering agents.
Author: Bahadori, H R|Green, M R|Catapano, C V
PMID: 11592339
Journal: Carcinogenesis. 2002 Jan;23(1):11-8.
Title: Induction of cell cycle arrest and apoptosis in human colon adenocarcinoma cell lines by beta-carotene through down-regulation of cyclin A and Bcl-2 family proteins.
Author: Palozza, Paola|Serini, Simona|Maggiano, Nicola|Angelini, Mara|Boninsegna, Alma|Di Nicuolo, Fiorella|Ranelletti, Franco O|Calviello, Gabriella
PMID: 11756218
Journal: J Clin Pathol. 2002 Mar;55(3):206-11.
Title: Differential expression of cell cycle and apoptosis related proteins in colorectal mucosa, primary colon tumours, and liver metastases.
Author: Backus, H H J|Van Groeningen, C J|Vos, W|Dukers, D F|Bloemena, E|Wouters, D|Pinedo, H M|Peters, G J
PMID: 11896073
Journal: Biochem Biophys Res Commun. 2002 Mar 29;292(2):347-54.
Title: Caspase-8 gene transduction augments radiation-induced apoptosis in DLD-1 cells.
Author: Uchida, Hiroaki|Shinoura, Nobusada|Kitayama, Joji|Watanabe, Toshiaki|Nagawa, Hirokazu|Hamada, Hirofumi
PMID: 11906168
Journal: Cancer Res. 2002 Mar 15;62(6):1583-7.
Title: Requirement of BAX for TRAIL/Apo2L-induced apoptosis of colorectal cancers: synergism with sulindac-mediated inhibition of Bcl-x(L).
Author: Ravi, Rajani|Bedi, Atul
PMID: 11912124
Journal: Clin Exp Metastasis. 2002;19(1):55-60.
Title: Stromal extracellular matrix reduces chemotherapy-induced apoptosis in colon cancer cell lines.
Author: Kouniavsky, Guenadi|Khaikin, Marat|Zvibel, Isabel|Zippel, Dov|Brill, Shlomo|Halpern, Zamir|Papa, Moshe
PMID: 11918083
Journal: Int J Cancer. 2002 Apr 1;98(4):498-504.
Title: Resistance of colon cancer cells to long-term 5-fluorouracil exposure is correlated to the relative level of Bcl-2 and Bcl-X(L) in addition to Bax and p53 status.
Author: Violette, Sabine|Poulain, Laurent|Dussaulx, Elisabeth|Pepin, Dominique|Faussat, Anne-Marie|Chambaz, Jean|Lacorte, Jean-Marc|Staedel, Cathy|Lesuffleur, Thecla
PMID: 11920608
Journal: Arch Pathol Lab Med. 2002 Jun;126(6):686-91.
Title: Increased apoptosis in infiltrating mononuclear cells of colorectal cancer: a mechanism for tumor escape.
Author: Chen, George G|Lee, Janet F Y|Chan, Ursula P F|Xu, Hu|Ip, Ping C|Lau, Wan Y
PMID: 12033956
Journal: Eur J Cancer Prev. 2002 Jun;11(3):271-81.
Title: Butyrate and aspirin in combination have an enhanced effect on apoptosis in human colorectal cancer cells.
Author: Menzel, T|Schauber, J|Kreth, F|Kudlich, T|Melcher, R|Gostner, A|Scheppach, W|Luhrs, H
PMID: 12131661
Journal: Gene Ther. 2002 Sep;9(18):1262-70.
Title: Mechanisms involved in development of resistance to adenovirus-mediated proapoptotic gene therapy in DLD1 human colon cancer cell line.
Author: Zhang, L|Gu, J|Lin, T|Huang, X|Roth, J A|Fang, B
PMID: 12215894
Journal: Cancer Res. 2002 Oct 15;62(20):5711-9.
Title: Benzylamide sulindac analogues induce changes in cell shape, loss of microtubules and G(2)-M arrest in a chronic lymphocytic leukemia (CLL) cell line and apoptosis in primary CLL cells.
Author: Moon, Eun-Yi|Lerner, Adam
PMID: 12384529
Journal: Int J Cancer. 2003 Jan 20;103(3):360-9.
Title: Apoptosis induced by cryo-injury in human colorectal cancer cells is associated with mitochondrial dysfunction.
Author: Yang, Weng-Lang|Addona, Tommaso|Nair, Deepak G|Qi, Lixin|Ravikumar, T S
PMID: 12471619
Journal: Gut. 2003 Jan;52(1):94-100.
Title: Butyrate induced Caco-2 cell apoptosis is mediated via the mitochondrial pathway.
Author: Ruemmele, F M|Schwartz, S|Seidman, E G|Dionne, S|Levy, E|Lentze, M J
PMID: 12477768
Journal: Biochem J. 2003 Apr 1;371(Pt 1):115-24.
Title: The anti-apoptotic effect of leukotriene D4 involves the prevention of caspase 8 activation and Bid cleavage.
Author: Wikstrom, Katarina|Juhas, Maria|Sjolander, Anita
PMID: 12482325
Journal: Gastroenterology. 2003 Jan;124(1):57-70.
Title: Expression of the leukotriene D4 receptor CysLT1, COX-2, and other cell survival factors in colorectal adenocarcinomas.
Author: Ohd, John F|Nielsen, Christian Kamp|Campbell, Joan|Landberg, Goran|Lofberg, Helge|Sjolander, Anita
PMID: 12512030
Journal: Carcinogenesis. 2003 Mar;24(3):605-11.
Title: Regional response leading to tumorigenesis after sulindac in small and large intestine of mice with Apc mutations.
Author: Yang, Kan|Fan, Kunhua|Kurihara, Naoto|Shinozaki, Hiroharu|Rigas, Basil|Augenlicht, Leonard|Kopelovich, Levy|Edelmann, Winfried|Kucherlapati, Raju|Lipkin, Martin
PMID: 12663524
Journal: Biochem Biophys Res Commun. 2003 Apr 11;303(3):756-63.
Title: Co-expression of bfl-1 enhances host response in the herpes simplex virus-thymidine kinase/ganciclovir gene therapy system.
Author: Kwon, Ghee Young|Jeong, Jaehoon|Woo, Jong Kyu|Choi, Hye Young|Lee, Min-Jung|Ko, Jae-Kyun|Shim, Yhong-Hee|Kim, Chul-Woo
PMID: 12670475
Journal: Genes Dev. 2003 Apr 1;17(7):832-7.
Title: Bcl-2 constitutively suppresses p53-dependent apoptosis in colorectal cancer cells.
Author: Jiang, Ming|Milner, Jo
PMID: 12670866
Journal: Biochem Pharmacol. 2003 Jul 1;66(1):93-103.
Title: Molecular mechanism of gossypol-induced cell growth inhibition and cell death of HT-29 human colon carcinoma cells.
Author: Zhang, Manchao|Liu, Hongpeng|Guo, Ribo|Ling, Yan|Wu, Xiaojin|Li, Bihua|Roller, Peter P|Wang, Shaomeng|Yang, Dajun
PMID: 12818369
Journal: J Agric Food Chem. 2003 Jul 2;51(14):3977-84.
Title: Induction of apoptosis by hydroxydibenzoylmethane through coordinative modulation of cyclin D3, Bcl-X(L), and Bax, release of cytochrome c, and sequential activation of caspases in human colorectal carcinoma cells.
Author: Pan, Min-Hsiung|Huang, Mei-Chen|Wang, Ying-Jan|Lin, Jen-Kun|Lin, Chao-Hsien
PMID: 12822933
Journal: Oncology. 2003;65(1):37-45.
Title: Increased expression of RelA/nuclear factor-kappa B protein correlates with colorectal tumorigenesis.
Author: Yu, Hong-Gang|Yu, Liang-Liang|Yang, Yanning|Luo, He-Sheng|Yu, Jie-Ping|Meier, Juris J|Schrader, Henning|Bastian, Andreas|Schmidt, Wolfgang E|Schmitz, Frank
PMID: 12837981
Journal: Am J Physiol Gastrointest Liver Physiol. 2003 Nov;285(5):G919-28. Epub 2003 Jul
Title: 5,6-Dichloro-ribifuranosylbenzimidazole- and apigenin-induced sensitization of colon cancer cells to TNF-alpha-mediated apoptosis.
Author: Farah, Myriam|Parhar, Kuljit|Moussavi, Maryam|Eivemark, Sharlene|Salh, Baljinder
PMID: 12842827
Journal: Clin Cancer Res. 2003 Jul;9(7):2856-65.
Title: Antisense Bcl-xl down-regulation switches the response to topoisomerase I inhibition from senescence to apoptosis in colorectal cancer cells, enhancing global cytotoxicity.
Author: Hayward, Richard L|Macpherson, Janet S|Cummings, Jeff|Monia, Brett P|Smyth, John F|Jodrell, Duncan I
PMID: 12855666
Journal: Int J Cancer. 2003 Sep 20;106(5):666-75.
Title: Nitric oxide suppresses apoptosis in human colon cancer cells by scavenging mitochondrial superoxide anions.
Author: Wenzel, Uwe|Kuntz, Sabine|De Sousa, Ulrike Jambor|Daniel, Hannelore
PMID: 12866025
Journal: J Cell Biochem. 2003 Aug 15;89(6):1102-14.
Title: Pro-apoptotic activity of transiently expressed BCL-2 occurs independent of BAX and BAK.
Author: Subramanian, T|Chinnadurai, G
PMID: 12898509
Journal: Oncogene. 2003 Aug 7;22(32):4953-63.
Title: The proteasome inhibitor PS-341 overcomes TRAIL resistance in Bax and caspase 9-negative or Bcl-xL overexpressing cells.
Author: Johnson, Thomas R|Stone, Kimberley|Nikrad, Malti|Yeh, Tammie|Zong, Wei-Xing|Thompson, Craig B|Nesterov, Alexandre|Kraft, Andrew S
PMID: 12902978
Journal: Cell Death Differ. 2003 Sep;10(9):1078-89.
Title: NF-kappaB-independent actions of sulfasalazine dissociate the CD95L- and Apo2L/TRAIL-dependent death signaling pathways in human malignant glioma cells.
Author: Hermisson, M|Weller, M
PMID: 12934082
Journal: Br J Cancer. 2003 Oct 6;89(7):1352-7.
Title: Bcl-x(L) antisense oligonucleotides radiosensitise colon cancer cells.
Author: Wacheck, V|Selzer, E|Gunsberg, P|Lucas, T|Meyer, H|Thallinger, C|Monia, B P|Jansen, B
PMID: 14520471
Journal: Oncol Rep. 2003 Nov-Dec;10(6):1723-8.
Title: Direct effects of octreotide, galanin and serotonin on human colon cancer cells.
Author: El-Salhy, Magdy|Starefeldt, Anna
PMID: 14534685
Journal: Anticancer Drugs. 2003 Oct;14(9):761-6.
Title: Induction of colon cancer cell death by 7-hydroxystaurosporine (UCN-01) is associated with increased p38 MAPK and decreased Bcl-xL.
Author: Chan, Ursula P F|Lee, Janet F Y|Wang, S H|Leung, Ka L|Chen, George G
PMID: 14551511
Journal: Ai Zheng. 2003 Nov;22(11):1135-9.
Title: [Relationship of Stat3 and its target gene products with malignancy in human colorectal carcinoma].
Author: Ma, Xiang-Tao|Wang, Shan|Ye, Ying-Jiang|Du, Ru-Yu|Cui, Zhi-Rong
PMID: 14613639
Journal: Cancer Res. 2003 Nov 15;63(22):7708-16.
Title: Insulin-like growth factor 1 receptor enhances invasion and induces resistance to apoptosis of colon cancer cells through the Akt/Bcl-x(L) pathway.
Author: Sekharam, Madhavi|Zhao, Haiyan|Sun, Mei|Fang, Quan|Zhang, Qingbo|Yuan, Zengqiang|Dan, Han C|Boulware, David|Cheng, Jin Q|Coppola, Domenico
PMID: 14633695
Journal: Mol Pharmacol. 2003 Dec;64(6):1494-502.
Title: Nitric oxide levels in human preneoplastic colonocytes determine their susceptibility toward antineoplastic agents.
Author: Wenzel, Uwe|Kuntz, Sabine|Daniel, Hannelore
PMID: 14645680
Journal: Clin Cancer Res. 2003 Dec 15;9(17):6504-15.
Title: Interferon-gamma-induced sensitization of colon carcinomas to ZD9331 targets caspases, downstream of Fas, independent of mitochondrial signaling and the inhibitor of apoptosis survivin.
Author: Geller, James|Petak, Istvan|Szucs, Kinga Szekely|Nagy, Katalin|Tillman, David M|Houghton, Janet A
PMID: 14695155
Journal: J Cell Biochem. 2004 Feb 1;91(2):410-22.
Title: Transcriptional regulation of TNF family receptors and Bcl-2 family by chemotherapeutic agents in murine CT26 cells.
Author: Choi, Kyoung-Han|Choi, Hye Young|Ko, Jae-Kyun|Park, Sung-Shin|Kim, Yong-Nyun|Kim, Chul-Woo
PMID: 14743399
Journal: Carcinogenesis. 2004 May;25(5):703-12.
Title: Ascorbic acid suppresses drug-induced apoptosis in human colon cancer cells by scavenging mitochondrial superoxide anions.
Author: Wenzel, Uwe|Nickel, Alexander|Kuntz, Sabine|Daniel, Hannelore
PMID: 14754875
Journal: Clin Cancer Res. 2004 Jan 15;10(2):784-93.
Title: Antitumor activity of ZD6474, a vascular endothelial growth factor receptor tyrosine kinase inhibitor, in human cancer cells with acquired resistance to antiepidermal growth factor receptor therapy.
Author: Ciardiello, Fortunato|Bianco, Roberto|Caputo, Roberta|Caputo, Rosa|Damiano, Vincenzo|Troiani, Teresa|Melisi, Davide|De Vita, Ferdinando|De Placido, Sabino|Bianco, A Raffaele|Tortora, Giampaolo
PMID: 14760102
Journal: Cancer Res. 2004 Feb 1;64(3):1110-3.
Title: Induction of apoptosis and down-regulation of Bcl-XL in cancer cells by a novel small molecule, 2[[3-(2,3-dichlorophenoxy)propyl]amino]ethanol.
Author: Wu, Shuhong|Zhu, Hongbo|Gu, Jian|Zhang, Lidong|Teraishi, Fuminori|Davis, John J|Jacob, Dietmar A|Fang, Bingliang
PMID: 14871845
Journal: Mol Cancer Ther. 2004 Feb;3(2):169-78.
Title: Enhanced oxaliplatin-induced apoptosis following antisense Bcl-xl down-regulation is p53 and Bax dependent: Genetic evidence for specificity of the antisense effect.
Author: Hayward, Richard L|Macpherson, Janet S|Cummings, Jeff|Monia, Brett P|Smyth, John F|Jodrell, Duncan I
PMID: 14985457
Journal: Carcinogenesis. 2004 Aug;25(8):1371-6.
Title: Inactivating mutations of proapoptotic Bad gene in human colon cancers.
Author: Lee, Jong Woo|Soung, Young Hwa|Kim, Su Young|Nam, Suk Woo|Kim, Chang Jae|Cho, Yong Gu|Lee, Jong Heun|Kim, Hong Sug|Park, Won Sang|Kim, Sang Ho|Lee, Jung Young|Yoo, Nam Jin|Lee, Sug Hyung
PMID: 15033904
Journal: Arch Biochem Biophys. 2004 Apr 15;424(2):119-27.
Title: Role of caspase activation in butyrate-induced terminal differentiation of HT29 colon carcinoma cells.
Author: Cai, Jiyang|Chen, Yan|Murphy, T J|Jones, Dean P|Sartorelli, Alan C
PMID: 15047183
Journal: Cell Res. 2004 Apr;14(2):117-24.
Title: LIGHT sensitizes IFN-gamma-mediated apoptosis of HT-29 human carcinoma cells through both death receptor and mitochondria pathways.
Author: Zhang, Man Chao|Liu, Hong Peng|Demchik, Lisa L|Zhai, Yi Fan|Yang, Da Jun
PMID: 15115612
Journal: Oncogene. 2004 Jun 24;23(29):4984-92.
Title: Induction of S-phase arrest and p21 overexpression by a small molecule 2[[3-(2,3-dichlorophenoxy)propyl] amino]ethanol in correlation with activation of ERK.
Author: Zhu, Hongbo|Zhang, Lidong|Wu, Shuhong|Teraishi, Fuminori|Davis, John J|Jacob, Dietmar|Fang, Bingliang
PMID: 15122344
Journal: J Biol Chem. 2004 Jul 16;279(29):30358-68. Epub 2004 May 3.
Title: Requirement of histone deacetylase activity for signaling by STAT1.
Author: Klampfer, Lidija|Huang, Jie|Swaby, Laurie-Anne|Augenlicht, Leonard
PMID: 15123634
Journal: Exp Mol Pathol. 2004 Jun;76(3):196-204.
Title: CD44 negatively regulates apoptosis in murine colonic epithelium via the mitochondrial pathway.
Author: Lakshman, Minalini|Subramaniam, Venkateswaran|Jothy, Serge
PMID: 15126101
Journal: World J Gastroenterol. 2004 Jun 1;10(11):1569-73.
Title: Constitutive activation of Stat3 signaling pathway in human colorectal carcinoma.
Author: Ma, Xiang-Tao|Wang, Shan|Ye, Ying-Jiang|Du, Ru-Yu|Cui, Zhi-Rong|Somsouk, Ma
PMID: 15162527
Journal: Carcinogenesis. 2004 Oct;25(10):1867-77. Epub 2004 Jun 17.
Title: Ectopic expression of Bcl-XL or Ku70 protects human colon cancer cells (SW480) against curcumin-induced apoptosis while their down-regulation potentiates it.
Author: Rashmi, Ramachandran|Kumar, Santhosh|Karunagaran, Devarajan
PMID: 15205359
Journal: Exp Mol Pathol. 2004 Aug;77(1):18-25.
Title: CD44 promotes resistance to apoptosis in human colon cancer cells.
Author: Lakshman, Minalini|Subramaniam, Venkateswaran|Rubenthiran, Umayal|Jothy, Serge
PMID: 15215046
Journal: World J Gastroenterol. 2004 Aug 1;10(15):2205-8.
Title: Honokiol induces apoptosis through p53-independent pathway in human colorectal cell line RKO.
Author: Wang, Tao|Chen, Fei|Chen, Zhe|Wu, Yi-Feng|Xu, Xiao-Li|Zheng, Shu|Hu, Xun
PMID: 15259066
Journal: Carcinogenesis. 2004 Nov;25(11):2247-55.
Title: IL-6-induced survival of colorectal carcinoma cells is inhibited by butyrate through down-regulation of the IL-6 receptor.
Author: Yuan, Hanna|Liddle, Forrester J|Mahajan, Sudipta|Frank, David A
PMID: 15284182
Journal: Apoptosis. 2004 Sep;9(5):619-27.
Title: Over-expression of Bcl-2 against Pteris semipinnata L-induced apoptosis of human colon cancer cells via a NF-kappa B-related pathway.
Author: Chen, G G|Liang, N-C|Lee, J F Y|Chan, U P F|Wang, S H|Leung, B C S|Leung, K L
PMID: 15314290
Journal: J Biol Chem. 2004 Oct 29;279(44):46113-21. Epub 2004 Aug 23.
Title: Expression of kinase-defective mutants of c-Src in human metastatic colon cancer cells decreases Bcl-xL and increases oxaliplatin- and Fas-induced apoptosis.
Author: Griffiths, Gareth J|Koh, Mei Yee|Brunton, Valerie G|Cawthorne, Christopher|Reeves, Natalie A|Greaves, Martin|Tilby, Michael J|Pearson, D Graham|Ottley, Christopher J|Workman, Paul|Frame, Margaret C|Dive, Caroline
PMID: 15326164
Journal: Int J Oncol. 2004 Oct;25(4):849-56.
Title: Angiotensin II activates MAP kinase and NF-kappaB through angiotensin II type I receptor in human pancreatic cancer cells.
Author: Amaya, Koji|Ohta, Tetsuo|Kitagawa, Hirohisa|Kayahara, Masato|Takamura, Hiroyuki|Fujimura, Takashi|Nishimura, Gen-Ichi|Shimizu, Koichi|Miwa, Koichi
PMID: 15375532
Journal: J Agric Food Chem. 2004 Oct 6;52(20):6330-7.
Title: Induction of apoptosis by shikonin through coordinative modulation of the Bcl-2 family, p27, and p53, release of cytochrome c, and sequential activation of caspases in human colorectal carcinoma cells.
Author: Hsu, Ping-Chi|Huang, Yu-Ting|Tsai, Mei-Ling|Wang, Ying-Jan|Lin, Jen-Kun|Pan, Min-Hsiung
PMID: 15453709
Journal: World J Gastroenterol. 2004 Nov 15;10(22):3255-60.
Title: Nuclear factor-kappaB p65 (RelA) transcription factor is constitutively activated in human colorectal carcinoma tissue.
Author: Yu, Liang-Liang|Yu, Hong-Gang|Yu, Jie-Ping|Luo, He-Sheng|Xu, Xi-Ming|Li, Jun-Hua
PMID: 15484295
Journal: Exp Biol Med (Maywood). 2004 Nov;229(10):1017-25.
Title: Dietary corn oil promotes colon cancer by inhibiting mitochondria-dependent apoptosis in azoxymethane-treated rats.
Author: Wu, Bin|Iwakiri, Ryuichi|Ootani, Akifumi|Tsunada, Seiji|Fujise, Takehiro|Sakata, Yasuhisa|Sakata, Hiroyuki|Toda, Shuji|Fujimoto, Kazuma
PMID: 15522837
Journal: Nutr Cancer. 2004;50(1):71-9.
Title: Conjugated docosahexaenoic acid is a potent inducer of cell cycle arrest and apoptosis and inhibits growth of colo 201 human colon cancer cells.
Author: Danbara, Naoyuki|Yuri, Takashi|Tsujita-Kyutoku, Miki|Sato, Mutsuya|Senzaki, Hideto|Takada, Hideho|Hada, Takahiko|Miyazawa, Teruo|Okazaki, Kazuichi|Tsubura, Airo
PMID: 15572300
Journal: Cancer Res. 2004 Dec 15;64(24):9105-14.
Title: Elimination of hepatic metastases of colon cancer cells via p53-independent cross-talk between irinotecan and Apo2 ligand/TRAIL.
Author: Ravi, Rajani|Jain, Ajay J|Schulick, Richard D|Pham, Vui|Prouser, Traci S|Allen, Heather|Mayer, Elizabeth Garrett|Yu, Hua|Pardoll, Drew M|Ashkenazi, Avi|Bedi, Atul
PMID: 15604280
Journal: Cancer Chemother Pharmacol. 2005 Jan;55(1):12-20.
Title: Docosahexaenoic acid enhances the susceptibility of human colorectal cancer cells to 5-fluorouracil.
Author: Calviello, Gabriella|Di Nicuolo, Fiorella|Serini, Simona|Piccioni, Elisabetta|Boninsegna, Alma|Maggiano, Nicola|Ranelletti, Franco O|Palozza, Paola
PMID: 15365767
Journal: Oncogene. 2005 Jan 6;24(1):148-56.
Title: The broad-range cyclin-dependent kinase inhibitor UCN-01 induces apoptosis in colon carcinoma cells through transcriptional suppression of the Bcl-x(L) protein.
Author: Bhonde, Mandar R|Hanski, Marie-Luise|Magrini, Roberta|Moorthy, Dhatchana|Muller, Antje|Sausville, Edward A|Kohno, Kimitoshi|Wiegand, Peter|Daniel, Peter T|Zeitz, Martin|Hanski, Christoph
PMID: 15467762
Journal: Cancer Lett. 2005 Jan 10;217(1):43-52.
Title: Norcantharidin-induced apoptosis in oral cancer cells is associated with an increase of proapoptotic to antiapoptotic protein ratio.
Author: Kok, Sang-Heng|Cheng, Shih-Jung|Hong, Chi-Yuan|Lee, Jang-Jaer|Lin, Sze-Kwan|Kuo, Ying-Shiung|Chiang, Chun-Pin|Kuo, Mark Yen-Ping
PMID: 15596295
Journal: Carcinogenesis. 2005 Apr;26(4):713-23. Epub 2005 Jan 20.
Title: Human colon cancer cells lacking Bax resist curcumin-induced apoptosis and Bax requirement is dispensable with ectopic expression of Smac or downregulation of Bcl-XL.
Author: Rashmi, Ramachandran|Kumar, Santhosh|Karunagaran, Devarajan
PMID: 15661804
Journal: Anticancer Drugs. 2005 Mar;16(3):263-75.
Title: EF24, a novel synthetic curcumin analog, induces apoptosis in cancer cells via a redox-dependent mechanism.
Author: Adams, Brian K|Cai, Jiyang|Armstrong, Jeff|Herold, Marike|Lu, Yang J|Sun, Aiming|Snyder, James P|Liotta, Dennis C|Jones, Dean P|Shoji, Mamoru
PMID: 15711178
Journal: Mol Cancer Ther. 2005 Mar;4(3):451-6.
Title: Bcl-XL small interfering RNA suppresses the proliferation of 5-fluorouracil-resistant human colon cancer cells.
Author: Zhu, Hongbo|Guo, Wei|Zhang, Lidong|Davis, John J|Teraishi, Fuminori|Wu, Shuhong|Cao, Xiaobo|Daniel, Jonathan|Smythe, W Roy|Fang, Bingliang
PMID: 15767554
Journal: World J Gastroenterol. 2005 Mar 14;11(10):1544-8.
Title: Connexin 26 correlates with Bcl-xL and Bax proteins expression in colorectal cancer.
Author: Kanczuga-Koda, Luiza|Sulkowski, Stanislaw|Koda, Mariusz|Skrzydlewska, Elzbieta|Sulkowska, Mariola
PMID: 15770735
Journal: Oncogene. 2005 Jul 21;24(31):4993-9.
Title: Bik/NBK accumulation correlates with apoptosis-induction by bortezomib (PS-341, Velcade) and other proteasome inhibitors.
Author: Zhu, Hongbo|Zhang, Lidong|Dong, Fengqin|Guo, Wei|Wu, Shuhong|Teraishi, Fuminori|Davis, John J|Chiao, Paul J|Fang, Bingliang
PMID: 15824729
Journal: Apoptosis. 2005 Mar;10(2):359-68.
Title: alpha-Lipoic acid induces apoptosis in human colon cancer cells by increasing mitochondrial respiration with a concomitant O2-*-generation.
Author: Wenzel, U|Nickel, A|Daniel, H
PMID: 15843897
Journal: Gut. 2005 Oct;54(10):1437-44.
Title: Possible role of REG Ialpha protein in ulcerative colitis and colitic cancer.
Author: Sekikawa, A|Fukui, H|Fujii, S|Nanakin, A|Kanda, N|Uenoyama, Y|Sawabu, T|Hisatsune, H|Kusaka, T|Ueno, S|Nakase, H|Seno, H|Fujimori, T|Chiba, T
PMID: 15914572
Journal: Jpn J Clin Oncol. 2005 Aug;35(8):453-63.
Title: Oxaliplatin, a potent inhibitor of survivin, enhances paclitaxel-induced apoptosis and mitotic catastrophe in colon cancer cells.
Author: Fujie, Yujiro|Yamamoto, Hirofumi|Ngan, Chew Yee|Takagi, Akimitsu|Hayashi, Taro|Suzuki, Rei|Ezumi, Koji|Takemasa, Ichiro|Ikeda, Masataka|Sekimoto, Mitsugu|Matsuura, Nariaki|Monden, Morito
PMID: 16024531
Journal: J Clin Pathol. 2005 Aug;58(8):811-4.
Title: Expression of apoptosis related proteins during malignant progression in chronic ulcerative colitis.
Author: van der Woude, C J|Moshage, H|Homan, M|Kleibeuker, J H|Jansen, P L M|van Dekken, H
PMID: 16049281
Journal: Cancer Biol Ther. 2005 Jul;4(7):781-6. Epub 2005 Jul 6.
Title: Proteasome inhibitors-mediated TRAIL resensitization and Bik accumulation.
Author: Zhu, Hongbo|Guo, Wei|Zhang, Lidong|Wu, Shuhong|Teraishi, Fuminori|Davis, John J|Dong, Fengqin|Fang, Bingliang
PMID: 16082182
Journal: Cell Cycle. 2005 Sep;4(9):1201-15.
Title: Molecular targets and anticancer potential of indole-3-carbinol and its derivatives.
Author: Aggarwal, Bharat B|Ichikawa, Haruyo
PMID: 16082211
Journal: Gastroenterology. 2005 Aug;129(2):577-90.
Title: Oncogenic potential of MEK1 in rat intestinal epithelial cells is mediated via cyclooxygenase-2.
Author: Komatsu, Koga|Buchanan, F Gregory|Katkuri, Sharada|Morrow, Jason D|Inoue, Hiroyasu|Otaka, Michiro|Watanabe, Sumio|DuBois, Raymond N
PMID: 16083714
Journal: Biochim Biophys Acta. 2005 Aug 15;1745(1):101-10. Epub 2005 Jan 11.
Title: Bcl-xL/Bax ratio is altered by IFNgamma in TNFalpha- but not in TRAIL-induced apoptosis in colon cancer cell line.
Author: Baillat, Gilbert|Garrouste, Francoise|Remacle-Bonnet, Maryse|Marvaldi, Jacques|Pommier, Gilbert
PMID: 16085058
Journal: Lab Invest. 2005 Nov;85(11):1357-67.
Title: Cyclooxygenase-2 protein reduces tamoxifen and N-(4-hydroxyphenyl)retinamide inhibitory effects in breast cancer cells.
Author: Tari, Ana M|Simeone, Ann-Marie|Li, Yu-Jiang|Gutierrez-Puente, Yolanda|Lai, Syeling|Symmans, William F
PMID: 16127422
Journal: World J Gastroenterol. 2005 Sep 7;11(33):5162-8.
Title: Novel rapid tissue lysis method to evaluate cancer proteins: correlation between elevated Bcl-X(L) expression and colorectal cancer cell proliferation.
Author: Chen, Wei-Shone|Chang, Hong-Yi|Chang, Jui-Ting|Liu, Jacqueline Ming|Li, Chung-Pin|Chen, Li-Li|Chang, Huei-Ling|Chen, Chia-Chi|Huang, Tze-Sing
PMID: 16127746
Journal: Clin Rev Allergy Immunol. 2005 Jun;28(3):187-96.
Title: Involvement of IL-6 in the pathogenesis of inflammatory bowel disease and colon cancer.
Author: Atreya, Raja|Neurath, Markus F
PMID: 16129903
Journal: Anticancer Res. 2005 May-Jun;25(3B):2269-76.
Title: Enterolactone induces apoptosis and inhibits growth of Colo 201 human colon cancer cells both in vitro and in vivo.
Author: Danbara, Naoyuki|Yuri, Takashi|Tsujita-Kyutoku, Miki|Tsukamoto, Reiko|Uehara, Norihisa|Tsubura, Airo
PMID: 16158974
Journal: Am J Pathol. 2005 Oct;167(4):969-80.
Title: Constitutive activation of JAK3/STAT3 in colon carcinoma tumors and cell lines: inhibition of JAK3/STAT3 signaling induces apoptosis and cell cycle arrest of colon carcinoma cells.
Author: Lin, Quan|Lai, Raymond|Chirieac, Lucian R|Li, Changping|Thomazy, Vilmos A|Grammatikakis, Ioannis|Rassidakis, George Z|Zhang, Wei|Fujio, Yasushi|Kunisada, Keita|Hamilton, Stanley R|Amin, Hesham M
PMID: 16192633
Journal: Cancer Res. 2005 Oct 1;65(19):8604-7.
Title: Overexpressed beta-catenin blocks nitric oxide-induced apoptosis in colonic cancer cells.
Author: Wang, Hongying|MacNaughton, Wallace K
PMID: 16204024
Journal: Zhonghua Yi Xue Za Zhi. 2005 Sep 21;85(36):2566-9.
Title: [Molecular mechanism of cyclooxygenase-2 inhibitor in inhibition of proliferation of colon cancer cells by modulating Stat5 signal transduction pathway].
Author: Ma, Xiang-tao|Yu, Li-wei|Wang, Shan|Zhang, Hui|Du, Ru-yu|Cui, Zhi-rong
PMID: 16321305
Journal: Cell Death Differ. 2006 Feb;13(2):189-201.
Title: Agonists of an ecdysone-inducible mammalian expression system inhibit Fas Ligand- and TRAIL-induced apoptosis in the human colon carcinoma cell line RKO.
Author: Oehme, I|Bosser, S|Zornig, M
PMID: 16082389
Journal: Prostate. 2006 Mar 1;66(4):430-8.
Title: Antitumor activity and downregulation of pro-angiogenic molecules in human prostate cancer cells by a novel thiazolidione compound.
Author: Teraishi, Fuminori|Wu, Shuhong|Inoue, Satoshi|Zhang, Lidong|Davis, John J|Guo, Wei|Dong, Fengqin|Fang, Bingliang
PMID: 16302260
Journal: Crit Rev Oncol Hematol. 2006 Feb;57(2):107-21.
Title: An overview of apoptosis and the prevention of colorectal cancer.
Author: Watson, Alastair J M
PMID: 16326109
Journal: Gastroenterology. 2006 Jan;130(1):137-49.
Title: Reg IV activates the epidermal growth factor receptor/Akt/AP-1 signaling pathway in colon adenocarcinomas.
Author: Bishnupuri, Kumar S|Luo, Qizhi|Murmu, Nabendu|Houchen, Courtney W|Anant, Shrikant|Dieckgraefe, Brian K
PMID: 16401477
Journal: Oncogene. 2006 May 25;25(22):3160-9.
Title: Overexpression of hRFI inhibits 5-fluorouracil-induced apoptosis in colorectal cancer cells via activation of NF-kappaB and upregulation of BCL-2 and BCL-XL.
Author: Konishi, T|Sasaki, S|Watanabe, T|Kitayama, J|Nagawa, H
PMID: 16407826
Journal: J Nutr Biochem. 2006 Sep;17(9):611-25.
Title: The dietary hydrolysable tannin punicalagin releases ellagic acid that induces apoptosis in human colon adenocarcinoma Caco-2 cells by using the mitochondrial pathway.
Author: Larrosa, Mar|Tomas-Barberan, Francisco A|Espin, Juan Carlos
PMID: 16426830
Journal: Carcinogenesis. 2006 Jun;27(6):1285-91. Epub 2006 Feb 23.
Title: Overexpression of p65/RelA potentiates curcumin-induced apoptosis in HCT116 human colon cancer cells.
Author: Collett, Gavin P|Campbell, Frederick C
PMID: 16497702
Journal: Mutat Res. 2006 Jul 25;599(1-2):76-87. Epub 2006 Feb 24.
Title: Comparison of growth inhibition profiles and mechanisms of apoptosis induction in human colon cancer cell lines by isothiocyanates and indoles from Brassicaceae.
Author: Pappa, Gerlinde|Lichtenberg, Maike|Iori, Renato|Barillari, Jessica|Bartsch, Helmut|Gerhauser, Clarissa
PMID: 16500682
Journal: J Biol Chem. 2006 Jun 9;281(23):15941-50.
Title: Vinblastine-induced apoptosis is mediated by discrete alterations in subcellular location, oligomeric structure, and activation status of specific Bcl-2 family members.
Author: Upreti, Meenakshi|Lyle, Christopher S|Skaug, Brian|Du, Lihua|Chambers, Timothy C
PMID: 16574665
Journal: J Biol Chem. 2006 Jun 9;281(23):16034-42. Epub 2006 Apr 11.
Title: PUMA Dissociates Bax and Bcl-X(L) to induce apoptosis in colon cancer cells.
Author: Ming, Lihua|Wang, Peng|Bank, Alexander|Yu, Jian|Zhang, Lin
PMID: 16608847
Journal: Virchows Arch. 2006 Jul;449(1):48-61. Epub 2006 Apr 13.
Title: Comparative study of T84 and T84SF human colon carcinoma cells: in vitro and in vivo ultrastructural and functional characterization of cell culture and metastasis.
Author: Alessandro, Riccardo|Di Bella, Maria Antonietta|Flugy, Anna Maria|Fontana, Simona|Damiani, Francesca|Corrado, Chiara|Colomba, Paolo|Todaro, Matilde|Russo, Domenica|Santoro, Alessandra|Kohn, Elise C|De Leo, Giacomo
PMID: 16612624
Journal: J Clin Pathol. 2006 Sep;59(9):942-6.
Title: A "field change" of inhibited apoptosis occurs in colorectal mucosa adjacent to colorectal adenocarcinoma.
Author: Badvie, S|Hanna-Morris, A|Andreyev, H J N|Cohen, P|Saini, S|Allen-Mersh, T G
PMID: 16679352
Journal: J Gastroenterol Hepatol. 2006 Jul;21(7):1108-14.
Title: Differential expression of Bcl-2, Bcl-XL and p53 in colorectal cancer.
Author: Han, Hye Seung|Park, Young-Mee|Hwang, Tae Sook
PMID: 16824061
Journal: Free Radic Biol Med. 2006 Aug 15;41(4):601-9.
Title: p21(Cip1/Waf1/Sdi1) protects against hyperoxia by maintaining expression of Bcl-X(L).
Author: Staversky, Rhonda J|Vitiello, Peter F|Gehen, Sean C|Helt, Christopher E|Rahman, Arshad|Keng, Peter C|O'Reilly, Michael A
PMID: 16863993
Journal: Int J Cancer. 2006 Nov 15;119(10):2443-54.
Title: Anticancer effects of amooranin in human colon carcinoma cell line in vitro and in nude mice xenografts.
Author: Ramachandran, Cheppail|Nair, P K Raveendran|Alamo, Arturo|Cochrane, Curtis Bruce|Escalon, Enrique|Melnick, Steven J
PMID: 16894569
Journal: Pathol Oncol Res. 2006;12(3):133-42. Epub 2006 Sep 23.
Title: Proteasome inhibitors sensitize colon carcinoma cells to TRAIL-induced apoptosis via enhanced release of Smac/DIABLO from the mitochondria.
Author: Nagy, Katalin|Szekely-Szuts, Kinga|Izeradjene, Kamel|Douglas, Leslie|Tillman, Mike|Barti-Juhasz, Helga|Dominici, Massimo|Spano, Carlotta|Luca Cervo, Gian|Conte, Pierfranco|Houghton, Janet A|Mihalik, Rudolf|Kopper, Laszlo|Petak, Istvan
PMID: 16998592
Journal: Int J Oncol. 2006 Nov;29(5):1279-86.
Title: Induction of apoptosis by the 16-kDa amino-terminal fragment of the insulin-like growth factor binding protein 3 in human colonic carcinoma cells.
Author: H-Zadeh, Akram M|Collard, Tracey J|Malik, Karim|Hicks, Diane J|Paraskeva, Chris|Williams, Ann C
PMID: 17016662
Journal: Clin Cancer Res. 2006 Nov 1;12(21):6532-9.
Title: 2-methoxyestradiol, an endogenous mammalian metabolite, radiosensitizes colon carcinoma cells through c-Jun NH2-terminal kinase activation.
Author: Zou, HuiChao|Adachi, Masaaki|Imai, Kohzoh|Hareyama, Masato|Yoshioka, Katsuji|Zhao, Shiguang|Shinomura, Yasuhisa
PMID: 17085668
Journal: Wei Sheng Yan Jiu. 2006 Sep;35(5):537-40.
Title: [Effect of ceramide on apoptosis of human colon cancer HT-29 cells].
Author: Zhang, Xiao-Feng|Li, Bai-Xiang|Ren, Rui
PMID: 17086696
Journal: Naunyn Schmiedebergs Arch Pharmacol. 2006 Dec;374(3):223-33.
Title: Investigation of anti-tumor mechanisms of K2154: characterization of tubulin isotypes, mitotic arrest and apoptotic machinery.
Author: Lu, Pin-Hsuan|Kung, Fan-Lu|Kuo, Sheng-Chu|Chueh, Shih-Chieh|Guh, Jih-Hwa
PMID: 17102938
Journal: Cancer Biol Ther. 2006 Dec;5(12):1714-20. Epub 2006 Dec 30.
Title: Dysregulation of Reg gene expression occurs early in gastrointestinal tumorigenesis and regulates anti-apoptotic genes.
Author: Bishnupuri, Kumar S|Luo, Qizhi|Korzenik, Joshua R|Henderson, Jeffrey O|Houchen, Courtney W|Anant, Shrikant|Dieckgraefe, Brian K
PMID: 17106246
Journal: Anticancer Res. 2006 Nov-Dec;26(6B):4313-26.
Title: Gypenosides induced apoptosis in human colon cancer cells through the mitochondria-dependent pathways and activation of caspase-3.
Author: Chen, Jung-Chou|Lu, Kung-Wen|Lee, Jau-Hong|Yeh, Chin-Chung|Chung, Jing-Gung
PMID: 17201150
Journal: Ann N Y Acad Sci. 2006 Dec;1090:265-75.
Title: Insulin-like growth factor-I receptor correlates with connexin 26 and Bcl-xL expression in human colorectal cancer.
Author: Sulkowski, Stanislaw|Kanczuga-Koda, Luiza|Koda, Mariusz|Wincewicz, Andrzej|Sulkowska, Mariola
PMID: 17384270
Journal: Cancer Immunol Immunother. 2007 Apr;56(4):527-33.
Title: Efficient tumor cell lysis mediated by a Bcl-X(L) specific T cell clone isolated from a breast cancer patient.
Author: Sorensen, Rikke Baek|Hadrup, Sine Reker|Kollgaard, Tania|Svane, Inge Marie|thor Straten, Per|Andersen, Mads Hald
PMID: 16850344
Journal: Am J Physiol Gastrointest Liver Physiol. 2007 Jan;292(1):G66-75.
Title: Induction of cell cycle arrest and apoptosis in HT-29 human colon cancer cells by the dietary compound luteolin.
Author: Lim, Do Y|Jeong, Yoonhwa|Tyner, Angela L|Park, Jung H Y
PMID: 16901994
Journal: Mol Carcinog. 2007 Mar;46(3):231-41.
Title: Pinocembrin triggers Bax-dependent mitochondrial apoptosis in colon cancer cells.
Author: Kumar, M A Suresh|Nair, Mangalam|Hema, P S|Mohan, John|Santhoshkumar, T R
PMID: 17186548
Journal: Eur J Pharmacol. 2007 Mar 15;559(1):1-13.
Title: Herbal diterpenoids induce growth arrest and apoptosis in colon cancer cells with increased expression of the nonsteroidal anti-inflammatory drug-activated gene.
Author: Ko, Joshua K S|Leung, Wan C|Ho, Wai K|Chiu, Pauline
PMID: 17258704
Journal: J Clin Pathol. 2007 Feb;60(2):173-9.
Title: STAT3 mRNA and protein expression in colorectal cancer: effects on STAT3-inducible targets linked to cell survival and proliferation.
Author: Lassmann, Silke|Schuster, Ingrid|Walch, Axel|Gobel, Heike|Jutting, Uta|Makowiec, Frank|Hopt, Ulrich|Werner, Martin
PMID: 17264243
Journal: Cancer Chemother Pharmacol. 2007 Oct;60(5):651-60.
Title: Short hairpin RNAs targeting Bcl-xL modulate senescence and apoptosis following SN-38 and irinotecan exposure in a colon cancer model.
Author: Guichard, S M|Hua, M L|Kang, P|Macpherson, J S|Jodrell, D I
PMID: 17273826
Journal: World J Gastroenterol. 2007 Feb 7;13(5):692-8.
Title: Early apoptosis and cell death induced by ATX-S10Na (II)-mediated photodynamic therapy are Bax- and p53-dependent in human colon cancer cells.
Author: Mitsunaga, Makoto|Tsubota, Akihito|Nariai, Kohichi|Namiki, Yoshihisa|Sumi, Makoto|Yoshikawa, Tetsuya|Fujise, Kiyotaka
PMID: 17278191
Journal: Dig Dis Sci. 2007 Apr;52(4):1128-33.
Title: Down-regulation of PGE2 by physiologic levels of celecoxib is not sufficient to induce apoptosis or inhibit cell proliferation in human colon carcinoma cell lines.
Author: Lev-Ari, Shahar|Kazanov, Dina|Liberman, Eliezer|Ben-Yosef, Rami|Arber, Nadir
PMID: 17342386
Journal: PPAR Res. 2007;2007:93416.
Title: Involvement of PPARs in Cell Proliferation and Apoptosis in Human Colon Cancer Specimens and in Normal and Cancer Cell Lines.
Author: Martinasso, G|Oraldi, M|Trombetta, A|Maggiora, M|Bertetto, O|Canuto, R A|Muzio, G
PMID: 17389773
Journal: Ann N Y Acad Sci. 2007 Jan;1095:53-61.
Title: Significant coexpression of GLUT-1, Bcl-xL, and Bax in colorectal cancer.
Author: Wincewicz, Andrzej|Sulkowska, Mariola|Koda, Mariusz|Kanczuga-Koda, Luiza|Witkowska, Ewa|Sulkowski, Stanislaw
PMID: 17404017
Journal: J Biol Chem. 2007 Jul 6;282(27):19273-81.
Title: Survivin down-regulation plays a crucial role in 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor-induced apoptosis in cancer.
Author: Kaneko, Reiko|Tsuji, Naoki|Asanuma, Koichi|Tanabe, Hiromi|Kobayashi, Daisuke|Watanabe, Naoki
PMID: 17472962
Journal: Br J Nutr. 2007 Oct;98(4):789-95. Epub 2007 May 10.
Title: The growth-inhibitory effects of tomatoes digested in vitro in colon adenocarcinoma cells occur through down regulation of cyclin D1, Bcl-2 and Bcl-xL.
Author: Palozza, Paola|Serini, Simona|Boninsegna, Alma|Bellovino, Diana|Lucarini, Massimo|Monastra, Giovanni|Gaetani, Sancia
PMID: 17490506
Journal: Pathology. 2007 Jun;39(3):334-8.
Title: Cumulative expression of HIF-1-alpha, Bax, Bcl-xL and P53 in human colorectal cancer.
Author: Wincewicz, Andrzei|Sulkowska, Mariola|Koda, Mariusz|Sulkowski, Stanislaw
PMID: 17558861
Journal: Mol Pharmacol. 2007 Sep;72(3):704-14. Epub 2007 Jun 19.
Title: Low-dose BBR3610 toxicity in colon cancer cells is p53-independent and enhanced by inhibition of epidermal growth factor receptor (ERBB1)-phosphatidyl inositol 3 kinase signaling.
Author: Mitchell, Clint|Kabolizadeh, Peyman|Ryan, John|Roberts, John D|Yacoub, Adly|Curiel, David T|Fisher, Paul B|Hagan, Michael P|Farrell, Nicholas P|Grant, Steven|Dent, Paul
PMID: 17578896
Journal: Int J Cancer. 2007 Oct 15;121(8):1670-9.
Title: Gossypol reduction of tumor growth through ROS-dependent mitochondria pathway in human colorectal carcinoma cells.
Author: Ko, Ching-Huai|Shen, Shing-Chuan|Yang, Liang-Yo|Lin, Cheng-Wei|Chen, Yen-Chou
PMID: 17597109
Journal: J Surg Res. 2007 Sep;142(1):184-94. Epub 2007 Jul 2.
Title: Modification of gene products involved in resistance to apoptosis in metastatic colon cancer cells: roles of Fas, Apaf-1, NFkappaB, IAPs, Smac/DIABLO, and AIF.
Author: Huerta, Sergio|Heinzerling, John H|Anguiano-Hernandez, Yu-Mei|Huerta-Yepez, Sara|Lin, Jeffrey|Chen, David|Bonavida, Benjamin|Livingston, Edward H
PMID: 17603079
Journal: Photochem Photobiol Sci. 2007 Jul;6(7):758-66.
Title: Necrosis predominates in the cell death of human colon adenocarcinoma HT-29 cells treated under variable conditions of photodynamic therapy with hypericin.
Author: Mikes, Jaromir|Kleban, Jan|Sackova, Veronika|Horvath, Viktor|Jamborova, Erika|Vaculova, Alena|Kozubik, Alois|Hofmanova, Jirina|Fedorocko, Peter
PMID: 17609769
Journal: Cancer Sci. 2007 Sep;98(9):1417-23.
Title: Lipoxygenase inhibitors induce death receptor 5/TRAIL-R2 expression and sensitize malignant tumor cells to TRAIL-induced apoptosis.
Author: Yoshida, Tatsushi|Shiraishi, Takumi|Horinaka, Mano|Nakata, Susumu|Yasuda, Takashi|Goda, Ahmed E|Wakada, Miki|Mizutani, Yoichi|Miki, Tsuneharu|Nishikawa, Akiyoshi|Sakai, Toshiyuki
PMID: 17645780
Journal: Arch Toxicol. 2007 Oct;81(10):719-28. Epub 2007 Aug 3.
Title: Berberine induces apoptosis in SW620 human colonic carcinoma cells through generation of reactive oxygen species and activation of JNK/p38 MAPK and FasL.
Author: Hsu, Wen-Hsiu|Hsieh, Yih-Shou|Kuo, Hsing-Chun|Teng, Chun-Yuh|Huang, Hai-I|Wang, Chau-Jong|Yang, Shun-Fa|Liou, Yi-Sheng|Kuo, Wu-Hsien
PMID: 17673978
Journal: Cell Signal. 2008 Jan;20(1):83-93. Epub 2007 Sep 11.
Title: Involvement of G proteins of the Rho family in the regulation of Bcl-2-like protein expression and caspase 3 activation by Gastrins.
Author: He, Hong|Yim, Mildred|Liu, Kevin H|Cody, Stephen C|Shulkes, Arthur|Baldwin, Graham S
PMID: 17936584
Journal: Front Biosci. 2008 Jan 1;13:2888-99.
Title: The role of signal transducers and activators of transcription in colon cancer.
Author: Klampfer, Lidija
PMID: 17981761
Journal: J Biol Chem. 2008 Feb 29;283(9):5950-9. Epub 2007 Dec 26.
Title: Mitochondrial targeting of adenomatous polyposis coli protein is stimulated by truncating cancer mutations: regulation of Bcl-2 and implications for cell survival.
Author: Brocardo, Mariana|Lei, Ying|Tighe, Anthony|Taylor, Stephen S|Mok, Myth T S|Henderson, Beric R
PMID: 18160396
Journal: World J Gastroenterol. 2008 Jan 21;14(3):428-34.
Title: Inhibition of signal transducer and activator of transcription 3 expression by RNA interference suppresses invasion through inducing anoikis in human colon cancer cells.
Author: Fan, Yu|Zhang, You-Li|Wu, Ying|Zhang, Wei|Wang, Yin-Huan|Cheng, Zhao-Ming|Li, Hua
PMID: 18200666
Journal: Am J Physiol Gastrointest Liver Physiol. 2008 May;294(5):G1235-44.
Title: CUGBP2 downregulation by prostaglandin E2 protects colon cancer cells from radiation-induced mitotic catastrophe.
Author: Natarajan, Gopalan|Ramalingam, Satish|Ramachandran, Ilangovan|May, Randal|Queimado, Lurdes|Houchen, Courtney W|Anant, Shrikant
PMID: 18325984
Journal: Cancer Res. 2008 Mar 15;68(6):1962-9.
Title: Diphenyl difluoroketone: a curcumin derivative with potent in vivo anticancer activity.
Author: Subramaniam, Dharmalingam|May, Randal|Sureban, Sripathi M|Lee, Katherine B|George, Robert|Kuppusamy, Periannan|Ramanujam, Rama P|Hideg, Kalman|Dieckgraefe, Brian K|Houchen, Courtney W|Anant, Shrikant
PMID: 18339878
Journal: Clin Cancer Res. 2008 Apr 1;14(7):2128-36.
Title: Curcumin sensitizes human colorectal cancer xenografts in nude mice to gamma-radiation by targeting nuclear factor-kappaB-regulated gene products.
Author: Kunnumakkara, Ajaikumar B|Diagaradjane, Parmeswaran|Guha, Sushovan|Deorukhkar, Amit|Shentu, Shujun|Aggarwal, Bharat B|Krishnan, Sunil
PMID: 18381954
Journal: Mol Nutr Food Res. 2008 May;52(5):527-37.
Title: 6-Shogaol induces apoptosis in human colorectal carcinoma cells via ROS production, caspase activation, and GADD 153 expression.
Author: Pan, Min-Hsiung|Hsieh, Min-Chi|Kuo, Jen-Min|Lai, Ching-Shu|Wu, Hou|Sang, Shengmin|Ho, Chi-Tang
PMID: 18384088
Journal: Mol Ther. 2008 May;16(5):886-92.
Title: Therapeutic molecular targeting of 15-lipoxygenase-1 in colon cancer.
Author: Wu, Yuanqing|Fang, Bingliang|Yang, Xiulan Q|Wang, Li|Chen, Dongning|Krasnykh, Victor|Carter, Bing Z|Morris, Jeffrey S|Shureiqi, Imad
PMID: 18388920
Journal: Biochem Pharmacol. 2008 Jun 15;75(12):2345-55.
Title: Role of Bax in quercetin-induced apoptosis in human prostate cancer cells.
Author: Lee, Dae-Hee|Szczepanski, Miroslaw|Lee, Yong J
PMID: 18455702
Journal: World J Gastroenterol. 2008 May 21;14(19):3069-73.
Title: Significance of Bcl-xL in human colon carcinoma.
Author: Zhang, You-Li|Pang, Li-Qun|Wu, Ying|Wang, Xiao-Yan|Wang, Chong-Qiang|Fan, Yu
PMID: 18494061
Journal: Int J Cancer. 2008 Aug 15;123(4):951-7.
Title: Simvastatin induces apoptosis in human colon cancer cells and in tumor xenografts, and attenuates colitis-associated colon cancer in mice.
Author: Cho, Soo-Jeong|Kim, Joo Sung|Kim, Jung Mogg|Lee, Jong Yeul|Jung, Hyun Chae|Song, In Sung
PMID: 18521906
Journal: Oncogene. 2008 Oct 9;27(46):6012-22.
Title: A mitochondrial block and expression of XIAP lead to resistance to TRAIL-induced apoptosis during progression to metastasis of a colon carcinoma.
Author: Ndozangue-Touriguine, O|Sebbagh, M|Merino, D|Micheau, O|Bertoglio, J|Breard, J
PMID: 18560353
Journal: Cancer Invest. 2008 Aug;26(7):708-17.
Title: Herbal isoprenols induce apoptosis in human colon cancer cells through transcriptional activation of PPARgamma.
Author: Au-Yeung, Kathy Ka-Wai|Liu, Po-Ling|Chan, Cecilia|Wu, Wing-Yee|Lee, Susanna Sau-Tuen|Ko, Joshua Ka-Shun
PMID: 18608213
Journal: World J Gastroenterol. 2008 Jun 28;14(24):3829-40.
Title: Bcl-x(L) and Myeloid cell leukaemia-1 contribute to apoptosis resistance of colorectal cancer cells.
Author: Schulze-Bergkamen, Henning|Ehrenberg, Roland|Hickmann, Lothar|Vick, Binje|Urbanik, Toni|Schimanski, Christoph-C|Berger, Martin-R|Schad, Arno|Weber, Achim|Heeger, Steffen|Galle, Peter-R|Moehler, Markus
PMID: 18609706
Journal: Zhonghua Zhong Liu Za Zhi. 2008 Apr;30(4):245-9.
Title: [Overcoming acquired resistance to tumor necrosis factor-related apoptosis-inducing ligand by Bcl-XL small interfering RNA in human colon cancer].
Author: Zhu, Hong-Bo|Huang, Xue-Feng|Hu, Jing-Zi|Zhou, Wei|Chen, Wei|Chen, Lin-Lin|He, Chao
PMID: 18788624
Journal: Int Immunopharmacol. 2008 Dec 20;8(13-14):1854-8.
Title: Rapamycin reverses TLR4 signaling-triggered tumor apoptosis resistance by disrupting Akt-mediated Bcl-xL upregulation.
Author: Sun, Qiaoling|Zheng, Yuanyuan|Liu, Qiuyan|Cao, Xuetao
PMID: 18789402
Journal: Hepatogastroenterology. 2008 Jul-Aug;55(85):1269-73.
Title: Evaluation of the immunohistochemical stain patterns of survivin, Bak and Bag-1 in colorectal cancers and comparison with polyps situated in the colon.
Author: Alper, Murat|Cukur, Selma|Belenli, Olcay|Suna, Mazlume
PMID: 18795671
Journal: Tumour Biol. 2008;29(5):287-303.
Title: c-myc antisense oligonucleotides sensitize human colorectal cancer cells to chemotherapeutic drugs.
Author: Abaza, Mohamed-Salah I|Al-Saffar, Amal|Al-Sawan, Shorooq|Al-Attiyah, Rajaa
PMID: 18802399
Journal: Exp Biol Med (Maywood). 2008 Dec;233(12):1554-60.
Title: Hexane/ethanol extract of Glycyrrhiza uralensis licorice suppresses doxorubicin-induced apoptosis in H9c2 rat cardiac myoblasts.
Author: Choi, Hyun Ju|Seon, Mi Ra|Lim, Soon Sung|Kim, Jong-Sang|Chun, Hyang Sook|Park, Jung Han Yoon
PMID: 18849542
Journal: Nutr Cancer. 2008;60 Suppl 1:98-103.
Title: NSAIDs downregulate Bcl-X(L) and dissociate BAX and Bcl-X(L) to induce apoptosis in colon cancer cells.
Author: Bank, Alexander|Yu, Jian|Zhang, Lin
PMID: 19003586
Journal: Clin Cancer Res. 2008 Dec 15;14(24):8132-42.
Title: Induction of Noxa sensitizes human colorectal cancer cells expressing Mcl-1 to the small-molecule Bcl-2/Bcl-xL inhibitor, ABT-737.
Author: Okumura, Kenji|Huang, Shengbing|Sinicrope, Frank A
PMID: 19088028
Journal: Environ Health Prev Med. 2008 Sep;13(5):281-7.
Title: Combination of isoliquiritigenin and tumor necrosis factor-related apoptosis-inducing ligand induces apoptosis in colon cancer HT29 cells.
Author: Yoshida, Tatsushi|Horinaka, Mano|Takara, Mami|Tsuchihashi, Mayuko|Mukai, Nobuhiro|Wakada, Miki|Sakai, Toshiyuki
PMID: 19568915
Journal: Cancer Immunol Immunother. 2009 May;58(5):699-708.
Title: Immunosensitization with a Bcl-2 small molecule inhibitor.
Author: Begley, Jonathan|Vo, Dan D|Morris, Lilah F|Bruhn, Kevin W|Prins, Robert M|Mok, Stephen|Koya, Richard C|Garban, Hermes J|Comin-Anduix, Begonya|Craft, Noah|Ribas, Antoni
PMID: 18807035
Journal: Food Chem Toxicol. 2009 Jan;47(1):171-9.
Title: Diallyl disulfide induces apoptosis in human colon cancer cell line (COLO 205) through the induction of reactive oxygen species, endoplasmic reticulum stress, caspases casade and mitochondrial-dependent pathways.
Author: Yang, Jai-Sing|Chen, Guang-Wei|Hsia, Te-Chun|Ho, Heng-Chien|Ho, Chin-Chin|Lin, Meng-Wei|Lin, Song-Shei|Yeh, Ru-Duan|Ip, Siu-Wan|Lu, Hsu-Fung|Chung, Jing-Gung
PMID: 19038304
Journal: Plant Foods Hum Nutr. 2009 Mar;64(1):11-7.
Title: Antiproliferation and apoptosis on RKO colon cancer by Millingtonia hortensis.
Author: Tansuwanwong, Siwapong|Yamamoto, Hiroyuki|Imai, Kohzoh|Vinitketkumnuen, Usanee
PMID: 19083098
Journal: Nitric Oxide. 2009 May;20(3):182-94.
Title: In vitro and in vivo sensitization of SW620 metastatic colon cancer cells to CDDP-induced apoptosis by the nitric oxide donor DETANONOate: Involvement of AIF.
Author: Huerta, Sergio|Baay-Guzman, Guillermina|Gonzalez-Bonilla, Cesar R|Livingston, Edward H|Huerta-Yepez, Sara|Bonavida, Benjamin
PMID: 19105980
Journal: Ann Surg Oncol. 2009 Mar;16(3):761-71.
Title: Inhibition of autophagy by 3-MA enhances the effect of 5-FU-induced apoptosis in colon cancer cells.
Author: Li, Jie|Hou, Ni|Faried, Ahmad|Tsutsumi, Soichi|Takeuchi, Toshiyuki|Kuwano, Hiroyuki
PMID: 19116755
Journal: Am J Pathol. 2009 Jan;174(1):317-29.
Title: Bacterial infection of Smad3/Rag2 double-null mice with transforming growth factor-beta dysregulation as a model for studying inflammation-associated colon cancer.
Author: Maggio-Price, Lillian|Treuting, Piper|Bielefeldt-Ohmann, Helle|Seamons, Audrey|Drivdahl, Rolf|Zeng, Weiping|Lai, LapHin|Huycke, Mark|Phelps, Susan|Brabb, Thea|Iritani, Brian M
PMID: 19119184
Journal: Apoptosis. 2009 Feb;14(2):203-17.
Title: Sodium butyrate sensitizes human colon adenocarcinoma COLO 205 cells to both intrinsic and TNF-alpha-dependent extrinsic apoptosis.
Author: Pajak, Beata|Gajkowska, Barbara|Orzechowski, Arkadiusz
PMID: 19130237
Journal: Int J Mol Med. 2009 Feb;23(2):189-96.
Title: Astragalus saponins induce apoptosis via an ERK-independent NF-kappaB signaling pathway in the human hepatocellular HepG2 cell line.
Author: Auyeung, Kathy Ka-wai|Law, Pui-ching|Ko, Joshua Ka-shun
PMID: 19148542
Journal: Cancer Sci. 2009 Mar;100(3):503-13.
Title: Formosanin C-induced apoptosis requires activation of caspase-2 and change of mitochondrial membrane potential.
Author: Lee, Jenq-Chang|Su, Chun-Li|Chen, Lin-Lin|Won, Shen-Jeu
PMID: 19154411
Journal: J Biol Chem. 2009 Apr 3;284(14):9176-83.
Title: HSF1-mediated BAG3 expression attenuates apoptosis in 4-hydroxynonenal-treated colon cancer cells via stabilization of anti-apoptotic Bcl-2 proteins.
Author: Jacobs, Aaron T|Marnett, Lawrence J
PMID: 19179333
Journal: Cancer Chemother Pharmacol. 2009 Oct;64(5):953-60.
Title: Prostaglandin synthase 2/cyclooxygenase 2 (PTGS2/COX2) 8473T>C polymorphism associated with prognosis for patients with colorectal cancer treated with capecitabine and oxaliplatin.
Author: Kim, Jong Gwang|Chae, Yee Soo|Sohn, Sang Kyun|Moon, Joon Ho|Ryoo, Hun Mo|Bae, Sung Hwa|Kum, Yoonseop|Jeon, Seong Woo|Lim, Kyoung-Hoon|Kang, Byung-Mo|Park, In-Ja|Choi, Gyu Seog|Jun, Soo-Han
PMID: 19219602
Journal: J Cell Biochem. 2009 Apr 15;106(6):1113-22.
Title: Magnolol induces apoptosis via inhibiting the EGFR/PI3K/Akt signaling pathway in human prostate cancer cells.
Author: Lee, Dae-Hee|Szczepanski, Miroslaw-Jerzy|Lee, Yong J
PMID: 19229860
Journal: Mol Pharmacol. 2009 Jul;76(1):192-200.
Title: S-Adenosylmethionine and methylthioadenosine inhibit cellular FLICE inhibitory protein expression and induce apoptosis in colon cancer cells.
Author: Li, Tony W H|Zhang, Qingsong|Oh, Pilsoo|Xia, Meng|Chen, Hui|Bemanian, Sean|Lastra, Natalie|Circ, Magda|Moyer, Mary Pat|Mato, Jose M|Aw, Tak Yee|Lu, Shelly C
PMID: 19372210
Journal: J Cell Biol. 2009 Apr 20;185(2):279-90.
Title: Bax activation by the BH3-only protein Puma promotes cell dependence on antiapoptotic Bcl-2 family members.
Author: Gallenne, Tristan|Gautier, Fabien|Oliver, Lisa|Hervouet, Eric|Noel, Belinda|Hickman, John A|Geneste, Olivier|Cartron, Pierre-Francois|Vallette, Francois M|Manon, Stephen|Juin, Philippe
PMID: 19380879
Journal: Cancer Lett. 2009 Sep 28;283(1):108-17.
Title: Growth-inhibitory effects of the astaxanthin-rich alga Haematococcus pluvialis in human colon cancer cells.
Author: Palozza, Paola|Torelli, Cristiana|Boninsegna, Alma|Simone, Rossella|Catalano, Assunta|Mele, Maria Cristina|Picci, Nevio
PMID: 19423215
Journal: Biotechnol J. 2009 Jul;4(7):1046-54.
Title: A putative role for human BFK in DNA damage-induced apoptosis.
Author: Ozoren, Nesrin|Inohara, Naohiro|Nunez, Gabriel
PMID: 19557800
Journal: Nutrition. 2009 Nov-Dec;25(11-12):1193-201.
Title: In vitro studies on the inhibition of colon cancer by butyrate and carnitine.
Author: Roy, Marie-Josee|Dionne, Serge|Marx, George|Qureshi, Ijaz|Sarma, Dittakavi|Levy, Emile|Seidman, Ernest G
PMID: 19619983
Journal: Int J Cancer. 2009 Nov 1;125(9):2187-97.
Title: Curcumin sensitizes human colorectal cancer to capecitabine by modulation of cyclin D1, COX-2, MMP-9, VEGF and CXCR4 expression in an orthotopic mouse model.
Author: Kunnumakkara, Ajaikumar B|Diagaradjane, Parmeswaran|Anand, Preetha|Harikumar, Kuzhuvelil B|Deorukhkar, Amit|Gelovani, Juri|Guha, Sushovan|Krishnan, Sunil|Aggarwal, Bharat B
PMID: 19623659
Journal: Anticancer Drugs. 2009 Oct;20(9):815-21.
Title: A novel histone deacetylase inhibitor, CG0006, induces cell death through both extrinsic and intrinsic apoptotic pathways.
Author: Hwang, Jung Jin|Kim, Yong Sook|Kim, Mi Joung|Jang, Sejin|Lee, Je-Hwan|Choi, Jene|Ro, Seonggu|Hyun, Young-Lan|Lee, Jung Shin|Kim, Choung-Soo
PMID: 19644355
Journal: Ann N Y Acad Sci. 2009 Aug;1171:116-23.
Title: Transforming growth factor-beta1 and regulators of apoptosis.
Author: Sulkowski, Stanislaw|Wincewicz, Andrzej|Sulkowska, Mariola|Koda, Mariusz
PMID: 19723045
Journal: J Zhejiang Univ Sci B. 2009 Sep;10(9):668-74.
Title: Ursolic acid inhibits proliferation and induces apoptosis of HT-29 colon cancer cells by inhibiting the EGFR/MAPK pathway.
Author: Shan, Jian-zhen|Xuan, Yan-yan|Zheng, Shu|Dong, Qi|Zhang, Su-zhan
PMID: 19735099
Journal: Int J Radiat Oncol Biol Phys. 2009 Oct 1;75(2):534-42.
Title: Curcumin modulates the radiosensitivity of colorectal cancer cells by suppressing constitutive and inducible NF-kappaB activity.
Author: Sandur, Santosh K|Deorukhkar, Amit|Pandey, Manoj K|Pabon, Ana Maria|Shentu, Shujun|Guha, Sushovan|Aggarwal, Bharat B|Krishnan, Sunil
PMID: 19735878
Journal: Oncogene. 2009 Dec 17;28(50):4421-33.
Title: A novel pro-apoptotic function of RACK1: suppression of Src activity in the intrinsic and Akt pathways.
Author: Mamidipudi, V|Cartwright, C A
PMID: 19767770
Journal: Cancer Res Treat. 2009 Sep;41(3):164-70.
Title: TNF-alpha downregulates E-cadherin and sensitizes response to gamma-irradiation in Caco-2 cells.
Author: Yi, Jae Youn|Jung, Yu-Jin|Choi, Sun Shim|Chung, Eunkyung
PMID: 19809566
Journal: Scand J Gastroenterol. 2009;44(12):1443-51.
Title: Immunoglobulin kappa and immunoglobulin lambda are required for expression of the anti-apoptotic molecule Bcl-xL in human colorectal cancer tissue.
Author: Yang, Shao-Bo|Chen, Xiao|Wu, Ben-Yan|Wang, Meng-Wei|Cai, Chang-Hao|Cho, Dan-Bi|Chong, Jasmine|Li, Ping|Tang, Shang-Guo|Yang, Ping-Chang
PMID: 19883274
Journal: Invest New Drugs. 2010 Feb;28(1):1-13.
Title: Novel herbal flavonoids promote apoptosis but differentially induce cell cycle arrest in human colon cancer cell.
Author: Auyeung, Kathy Ka-Wai|Ko, Joshua Ka-Shun
PMID: 19139819
Journal: Gastroenterology. 2010 Feb;138(2):616-26, 626.e1-2.
Title: Reg IV regulates normal intestinal and colorectal cancer cell susceptibility to radiation-induced apoptosis.
Author: Bishnupuri, Kumar S|Luo, Qizhi|Sainathan, Satheesh K|Kikuchi, Kento|Sureban, Sripathi M|Sabarinathan, Mekala|Gross, Jennifer H|Aden, Konrad|May, Randal|Houchen, Courtney W|Anant, Shrikant|Dieckgraefe, Brian K
PMID: 19900450
Journal: Int J Cancer. 2010 Jul 15;127(2):474-84.
Title: Identification of stemonamide synthetic intermediates as a novel potent anticancer drug with an apoptosis-inducing ability.
Author: Li, Ying-Yi|Wang, Ying-Ying|Taniguchi, Tsuyoshi|Kawakami, Takahiro|Baba, Tomohisa|Ishibashi, Hiroyuki|Mukaida, Naofumi
PMID: 19921695
Journal: Int J Cancer. 2010 Sep 1;127(5):1072-80.
Title: Functional screening identifies a microRNA, miR-491 that induces apoptosis by targeting Bcl-X(L) in colorectal cancer cells.
Author: Nakano, Haruo|Miyazawa, Tatsuya|Kinoshita, Keita|Yamada, Yoji|Yoshida, Tetsuo
PMID: 20039318
Journal: PLoS One. 2010 Jan 18;5(1):e8755.
Title: Differential dependence on Beclin 1 for the regulation of pro-survival autophagy by Bcl-2 and Bcl-xL in HCT116 colorectal cancer cells.
Author: Priault, Muriel|Hue, Erika|Marhuenda, Fanny|Pilet, Paul|Oliver, Lisa|Vallette, Francois M
PMID: 20090905
Journal: Autophagy. 2010 Feb;6(2):256-69. Epub 2010 Feb 6.
Title: Celecoxib-induced apoptosis is enhanced by ABT-737 and by inhibition of autophagy in human colorectal cancer cells.
Author: Huang, Shengbing|Sinicrope, Frank A
PMID: 20104024
Journal: Anticancer Res. 2010 Jan;30(1):157-66.
Title: PPARgamma ligand 15-deoxy-delta 12,14-prostaglandin J2 sensitizes human colon carcinoma cells to TWEAK-induced apoptosis.
Author: Dionne, Serge|Levy, Emile|Levesque, Denise|Seidman, Ernest G
PMID: 20150631
Journal: Clin Cancer Res. 2010 Apr 15;16(8):2320-32.
Title: Histone deacetylase inhibitors and 15-deoxy-Delta12,14-prostaglandin J2 synergistically induce apoptosis.
Author: Koyama, Makoto|Izutani, Yasuyuki|Goda, Ahmed E|Matsui, Taka-aki|Horinaka, Mano|Tomosugi, Mitsuhiro|Fujiwara, Jun|Nakamura, Yoshitaka|Wakada, Miki|Yogosawa, Shingo|Sowa, Yoshihiro|Sakai, Toshiyuki
PMID: 20371690
Journal: Anticancer Res. 2010 Mar;30(3):785-92.
Title: Synthetic triterpenoids inhibit growth, induce apoptosis and suppress pro-survival Akt, mTOR and NF-{kappa}B signaling proteins in colorectal cancer cells.
Author: Gao, Xiaohua|Deeb, Dorrah|Hao, Jiang|Liu, Yongbo|Arbab, Ali S|Dulchavsky, Scott A|Gautam, Subhash C
PMID: 20392997
Journal: Cancer Biol Ther. 2010 Aug 15;10(4):354-61. Epub 2010 Aug 18.
Title: Janus-activated kinases and signal transducer and activator of transcription control tumor growth response to camptothecin in human colon cancer cells.
Author: Yun, Hyun Jin|Kim, Sun Young|Kwon, Young Yon|Kim, Chun-Ho|Kang, Chang-Mo|Kim, Eun Ju
PMID: 20534983
Journal: BMC Cancer. 2010 Jul 24;10:392.
Title: Cinnamon extract induces tumor cell death through inhibition of NFkappaB and AP1.
Author: Kwon, Ho-Keun|Hwang, Ji-Sun|So, Jae-Seon|Lee, Choong-Gu|Sahoo, Anupama|Ryu, Jae-Ha|Jeon, Won Kyung|Ko, Byoung Seob|Im, Chang-Rok|Lee, Sung Haeng|Park, Zee Yong|Im, Sin-Hyeog
PMID: 20653974
Journal: Mol Cancer Ther. 2010 Aug;9(8):2196-207.
Title: Gamma-tocotrienol promotes TRAIL-induced apoptosis through reactive oxygen species/extracellular signal-regulated kinase/p53-mediated upregulation of death receptors.
Author: Kannappan, Ramaswamy|Ravindran, Jayaraj|Prasad, Sahdeo|Sung, Bokyung|Yadav, Vivek R|Reuter, Simone|Chaturvedi, Madan M|Aggarwal, Bharat B
PMID: 20682650
Journal: Arch Pharm (Weinheim). 2010 Sep;343(9):489-99.
Title: Curcumin in cancer chemoprevention: molecular targets, pharmacokinetics, bioavailability, and clinical trials.
Author: Shehzad, Adeeb|Wahid, Fazli|Lee, Young Sup
PMID: 20726007
Journal: Regul Pept. 2010 Dec 10;165(2-3):224-31.
Title: The C-terminal flanking peptide (CTFP) of progastrin inhibits apoptosis via a PI3-kinase-dependent pathway.
Author: Patel, Oneel|Marshall, Kathryn M|Bramante, Gianni|Baldwin, Graham S|Shulkes, Arthur
PMID: 20727916
Journal: PLoS One. 2010 Aug 23;5(8):e12341.
Title: Cyclin B1/Cdk1 phosphorylation of mitochondrial p53 induces anti-apoptotic response.
Author: Nantajit, Danupon|Fan, Ming|Duru, Nadire|Wen, Yunfei|Reed, John C|Li, Jian Jian
PMID: 20808790
Journal: J Biol Chem. 2010 Nov 12;285(46):35418-27.
Title: Gossypol induces death receptor-5 through activation of the ROS-ERK-CHOP pathway and sensitizes colon cancer cells to TRAIL.
Author: Sung, Bokyung|Ravindran, Jayaraj|Prasad, Sahdeo|Pandey, Manoj K|Aggarwal, Bharat B
PMID: 20837473
Journal: J Biomed Sci. 2010 Sep 17;17:76.
Title: Suberoylanilide hydroxamic acid induces apoptosis and sub-G1 arrest of 320 HSR colon cancer cells.
Author: Sun, Pei-Chang|Tzao, Ching|Chen, Ban-Hen|Liu, Chen-Wei|Yu, Cheng-Ping|Jin, Jong-Shiaw
PMID: 20846458
Journal: Hepatogastroenterology. 2010 Jul-Aug;57(101):741-5.
Title: GLUT1 and Bcl-xL in relation to erythropoietin in human colorectal adenocarcinomas.
Author: Wincewicz, Andrzej|Baltaziak, Marek|Kanczuga-Koda, Luiza|Koda, Mariusz|Sulkowska, Urszula|Sulkowski, Stanislaw
PMID: 21033220
Journal: Zhonghua Zhong Liu Za Zhi. 2010 Aug;32(8):570-4.
Title: [Effect of APRIL on growth and apoptosis in transplanted tumor with human colorectal cancer cell line SW480 in nude mice].
Author: Wang, Jing-chun|Ding, Wei-feng|Sun, Bao-lan|Jing, Rong-rong|Huang, Hua|Wang, Hui-min
PMID: 21122406
Journal: Int J Clin Exp Pathol. 2010 Oct 12;3(8):768-74.
Title: Correlation between Mcl-1 and pAKT protein expression in colorectal cancer.
Author: Henderson-Jackson, Evita B|Helm, James|Ghayouri, Masoumeh|Hakam, Ardeshir|Nasir, Aejaz|Leon, Marino|Bui, Marilyn|Yeatman, Timothy|Coppola, Domenico
PMID: 21151390
Journal: Mol Med Rep. 2010 Nov-Dec;3(6):1031-4.
Title: Establishment and characterization of irinotecan-resistant human non-small cell lung cancer A549 cells.
Author: Ikeda, Ryuji|Vermeulen, Lee C|Lau, Elim|Jiang, Zhisheng|Pomplun, Marcia|Kolesar, Jill M
PMID: 21472350
Journal: Cell Death Differ. 2011 Feb;18(2):235-47.
Title: Bcl-2 family interaction with the mitochondrial morphogenesis machinery.
Author: Cleland, M M|Norris, K L|Karbowski, M|Wang, C|Suen, D-F|Jiao, S|George, N M|Luo, X|Li, Z|Youle, R J
PMID: 20671748
Journal: Int J Colorectal Dis. 2011 Jan;26(1):13-22.
Title: Aspirin promotes apoptosis in a murine model of colorectal cancer by mechanisms involving downregulation of IL-6-STAT3 signaling pathway.
Author: Tian, Yun|Ye, Ying|Gao, Wei|Chen, Hong|Song, Ting|Wang, Daqing|Mao, Xiaoyun|Ren, Changshan
PMID: 20886344
Journal: Curr Pharm Biotechnol. 2011 Feb 1;12(2):261-7.
Title: Zebrafish stem cell differentiation stage factors suppress Bcl-xL release and enhance 5-Fu-mediated apoptosis in colon cancer cells.
Author: D'Anselmi, F|Cucina, A|Biava, P M|Proietti, S|Coluccia, P|Frati, L|Bizzarri, M
PMID: 21043999
Journal: J Appl Microbiol. 2011 Jan;110(1):304-13.
Title: Apoptosis-inducing effect of diketopiperazine disulfides produced by Aspergillus sp. KMD 901 isolated from marine sediment on HCT116 colon cancer cell lines.
Author: Choi, E J|Park, J-S|Kim, Y-J|Jung, J-H|Lee, J K|Kwon, H C|Yang, H O
PMID: 21122037
Journal: Pharm Res. 2011 Apr;28(4):827-38.
Title: Difluorinated-curcumin (CDF): a novel curcumin analog is a potent inhibitor of colon cancer stem-like cells.
Author: Kanwar, Shailender Singh|Yu, Yingjie|Nautiyal, Jyoti|Patel, Bhaumik B|Padhye, Subhash|Sarkar, Fazlul H|Majumdar, Adhip P N
PMID: 21161336
Journal: Oncol Rep. 2011 Apr;25(4):1091-8.
Title: CIAPIN1 confers multidrug resistance through up-regulation of MDR-1 and Bcl-L in LoVo/Adr cells and is independent of p53.
Author: Zhang, Ya-Fei|Li, Xiao-Hua|Shi, Yong-Quan|Wu, Yu-Yun|Li, Ning|He, Qiang|Ji, Qing|Wang, Rong-Quan|Yang, Shi-Ming|Fang, Dian-Chun
PMID: 21240465
Journal: PLoS One. 2011 Jan 17;6(1):e16241.
Title: TNFalpha cooperates with IFN-gamma to repress Bcl-xL expression to sensitize metastatic colon carcinoma cells to TRAIL-mediated apoptosis.
Author: Liu, Feiyan|Hu, Xiaolin|Zimmerman, Mary|Waller, Jennifer L|Wu, Ping|Hayes-Jordan, Andrea|Lev, Dina|Liu, Kebin
PMID: 21264227
Journal: Acta Histochem. 2011 Dec;113(8):810-4.
Title: Prognostic significance of Bcl-xL gene expression in human colorectal cancer.
Author: Jin-Song, Yang|Zhao-Xia, Wang|Cheng-Yu, Lv|Xiao-Di, Liang|Ming, Sun|Yuan-Yuan, Guo|Wei, De
PMID: 21277008
Journal: PLoS One. 2011 Feb 15;6(2):e16916.
Title: ZIC1 is downregulated through promoter hypermethylation, and functions as a tumor suppressor gene in colorectal cancer.
Author: Gan, Lihong|Chen, Shujie|Zhong, Jing|Wang, Xian|Lam, Emily K Y|Liu, Xin|Zhang, Jianbin|Zhou, Tianhua|Yu, Jun|Si, Jianmin|Wang, Liangjing|Jin, Hongchuan
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Journal: Cancer Lett. 2011 May 1;304(1):52-9.
Title: miR-203 reverses chemoresistance in p53-mutated colon cancer cells through downregulation of Akt2 expression.
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Journal: J Nat Prod. 2011 Apr 25;74(4):701-6.
Title: Cytotoxic and antineoplastic activity of timosaponin A-III for human colon cancer cells.
Author: Kang, You-Jin|Chung, Hwa-Jin|Nam, Joo-Won|Park, Hyen Joo|Seo, Eun Kyoung|Kim, Yeong Shik|Lee, Dongho|Lee, Sang Kook
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Journal: Arch Pharm Res. 2011 Feb;34(2):323-30.
Title: Role of nonsteroidal anti-inflammatory drug-activated gene-1 in docetaxel-induced cell death of human colorectal cancer cells with different p53 status.
Author: Kim, Il-Yeob|Park, Su-Young|Kang, Youra|Thapa, Dinesh|Choi, Han Gon|Kim, Jung-Ae
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Journal: Gastroenterology. 2011 Aug;141(2):663-73.
Title: Oxaliplatin sensitizes human colon cancer cells to TRAIL through JNK-dependent phosphorylation of Bcl-xL.
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Journal: Chin J Integr Med. 2011 Aug;17(8):607-11.
Title: Proliferation-inhibiting and apoptosis-inducing effects of ursolic acid and oleanolic acid on multi-drug resistance cancer cells in vitro.
Author: Shan, Jian-zhen|Xuan, Yan-yan|Ruan, Shu-qin|Sun, Mei
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Journal: Eur J Pharm Sci. 2011 Nov 20;44(4):479-86.
Title: Novel selective Cox-2 inhibitors induce apoptosis in Caco-2 colorectal carcinoma cell line.
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Journal: World J Surg Oncol. 2011 Oct 4;9:117.
Title: Adenovirus-mediated siRNA targeting Bcl-xL inhibits proliferation, reduces invasion and enhances radiosensitivity of human colorectal cancer cells.
Author: Yang, Jinsong|Sun, Ming|Zhang, Aiping|Lv, Chengyu|De, Wei|Wang, Zhaoxia
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Journal: PLoS One. 2011;6(9):e25370.
Title: Acetylation of the proto-oncogene EVI1 abrogates Bcl-xL promoter binding and induces apoptosis.
Author: Pradhan, Anjan Kumar|Mohapatra, Alok Das|Nayak, Kasturi Bala|Chakraborty, Soumen
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Journal: Mol Cancer Ther. 2011 Dec;10(12):2373-83.
Title: The novel Bcl-2 inhibitor ABT-737 is more effective in hypoxia and is able to reverse hypoxia-induced drug resistance in neuroblastoma cells.
Author: Klymenko, Tetyana|Brandenburg, Martin|Morrow, Christopher|Dive, Caroline|Makin, Guy
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Journal: Biochem Biophys Res Commun. 2011 Dec 16;416(3-4):246-51.
Title: STAT3 signaling pathway is necessary for cell survival and tumorsphere forming capacity in ALDH(+)/CD133(+) stem cell-like human colon cancer cells.
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Journal: World J Gastroenterol. 2011 Nov 28;17(44):4905-10.
Title: Prognostic role of sensitive-to-apoptosis gene expression in rectal cancer.
Author: Ozden, Sevgi A|Ozyurt, Hazan|Ozgen, Zerrin|Kilinc, Olca|Oncel, Mustafa|Gul, Aylin E|Karadayi, Nimet|Serakinci, Nedime|Kan, Beki|Orun, Oya
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Journal: Acta Histochem. 2012 Feb;114(2):182; author reply 183.
Title: Re: Prognostic significance of Bcl-xL gene expression in human colorectal cancer.
Author: Wiwanitkit, Viroj
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Journal: Int J Obes (Lond). 2012 Feb;36(2):273-80.
Title: Effects of diet-induced obesity on colitis-associated colon tumor formation in A/J mice.
Author: Park, S-Y|Kim, J-S|Seo, Y-R|Sung, M-K
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Journal: Int J Cancer. 2012 May 1;130(9):2176-84.
Title: Boswellic acid inhibits growth and metastasis of human colorectal cancer in orthotopic mouse model by downregulating inflammatory, proliferative, invasive and angiogenic biomarkers.
Author: Yadav, Vivek R|Prasad, Sahdeo|Sung, Bokyung|Gelovani, Juri G|Guha, Sushovan|Krishnan, Sunil|Aggarwal, Bharat B
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Journal: Colorectal Dis. 2012 Feb;14(2):e64-71.
Title: Apoptotic proteins as prognostic markers and indicators of radiochemosensitivity in stage II/III rectal cancers.
Author: Fucini, C|Messerini, L|Saieva, C|Orzalesi, L|Carroni, V|Bartolini, N
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Journal: Mol Carcinog. 2012 Nov;51(11):869-80.
Title: A high-fat diet increases angiogenesis, solid tumor growth, and lung metastasis of CT26 colon cancer cells in obesity-resistant BALB/c mice.
Author: Park, Heesook|Kim, Minhee|Kwon, Gyoo Taik|Lim, Do Young|Yu, Rina|Sung, Mi-Kyung|Lee, Ki Won|Daily, James W 3rd|Park, Jung Han Yoon
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Journal: Int J Oncol. 2012 Jan;40(1):170-5.
Title: Anti-carcinogenic properties of omeprazole against human colon cancer cells and azoxymethane-induced colonic aberrant crypt foci formation in rats.
Author: Patlolla, Jagan M R|Zhang, Yuting|Li, Qian|Steele, Vernon E|Rao, Chinthalapally V
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Journal: J Pathol. 2012 Feb;226(3):442-50.
Title: BCL2L1 has a functional role in colorectal cancer and its protein expression is associated with chromosome 20q gain.
Author: Sillars-Hardebol, Anke H|Carvalho, Beatriz|Belien, Jeroen Am|de Wit, Meike|Delis-van Diemen, Pien M|Tijssen, Marianne|van de Wiel, Mark A|Ponten, Fredrik|Fijneman, Remond Ja|Meijer, Gerrit A
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Journal: Oncol Rep. 2012 Feb;27(2):339-46.
Title: shRNA against CD44 inhibits cell proliferation, invasion and migration, and promotes apoptosis of colon carcinoma cells.
Author: Park, Yeon Sun|Huh, Jung Wook|Lee, Jae Hyuk|Kim, Hyeong Rok
PMID: 22076607
Journal: Mol Cell Biochem. 2012 Apr;363(1-2):1-10.
Title: Targeting of colorectal cancer growth, metastasis, and anti-apoptosis in BALB/c nude mice via APRIL siRNA.
Author: Wang, Jingchun|Ding, Weifeng|Sun, Baolan|Jing, Rongrong|Huang, Hua|Shi, Gongsheng|Wang, Huimin
PMID: 22170570
Journal: PLoS One. 2012;7(1):e29750.
Title: MicroRNA-211 expression promotes colorectal cancer cell growth in vitro and in vivo by targeting tumor suppressor CHD5.
Author: Cai, Chunxiao|Ashktorab, Hassan|Pang, Xiaowu|Zhao, Yuan|Sha, Wei|Liu, Yulan|Gu, Xinbin
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Journal: Mol Cell. 2012 Mar 30;45(6):731-42.
Title: The mitochondrial ATPase inhibitory factor 1 triggers a ROS-mediated retrograde prosurvival and proliferative response.
Author: Formentini, Laura|Sanchez-Arago, Maria|Sanchez-Cenizo, Laura|Cuezva, Jose M
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Journal: PLoS One. 2012;7(2):e31762.
Title: Sub-lethal irradiation of human colorectal tumor cells imparts enhanced and sustained susceptibility to multiple death receptor signaling pathways.
Author: Ifeadi, Victoria|Garnett-Benson, Charlie
PMID: 22389673
Journal: Zhonghua Wei Chang Wai Ke Za Zhi. 2012 Mar;15(3):292-4.
Title: [Anti-tumor effect of adenovirus-mediated Bcl-XL shRNA in vitro].
Author: Zhu, Yu-ping|Li, De-chuan|Feng, Hai-yang|Liu, Yong|Qian, Jun|Chen, Yin-bo|Gao, Yun
PMID: 22454181
Journal: J Immunol. 2012 May 1;188(9):4441-9.
Title: Decitabine and vorinostat cooperate to sensitize colon carcinoma cells to Fas ligand-induced apoptosis in vitro and tumor suppression in vivo.
Author: Yang, Dafeng|Torres, Christina M|Bardhan, Kankana|Zimmerman, Mary|McGaha, Tracy L|Liu, Kebin
PMID: 22461695
Journal: Toxicol Appl Pharmacol. 2012 May 15;261(1):31-41.
Title: Preclinical evaluation of destruxin B as a novel Wnt signaling target suppressing proliferation and metastasis of colorectal cancer using non-invasive bioluminescence imaging.
Author: Yeh, Chi-Tai|Rao, Yerra Koteswara|Ye, Min|Wu, Wen-Shi|Chang, Tung-Chen|Wang, Liang-Shun|Wu, Chih-Hsiung|Wu, Alexander T H|Tzeng, Yew-Min
PMID: 22465936
Journal: Oncol Rep. 2012 Jul;28(1):384-8.
Title: The histone deacetylase inhibitor trichostatin A induces cell cycle arrest and apoptosis in colorectal cancer cells via p53-dependent and -independent pathways.
Author: Meng, Jin|Zhang, Hai-Hua|Zhou, Chun-Xiang|Li, Chen|Zhang, Feng|Mei, Qi-Bing
PMID: 22552631
Journal: Molecules. 2012 May 16;17(5):5780-94.
Title: Luffa echinata Roxb. induces human colon cancer cell (HT-29) death by triggering the mitochondrial apoptosis pathway.
Author: Shang, Li-Hua|Li, Chun-Mei|Yang, Zhao-Yang|Che, De-Hai|Cao, Jing-Yan|Yu, Yan
PMID: 22592084
Journal: Dig Dis Sci. 2012 Nov;57(11):2873-82.
Title: Deguelin, an Akt inhibitor, down-regulates NF-kappaB signaling and induces apoptosis in colon cancer cells and inhibits tumor growth in mice.
Author: Kang, Hyoun Woo|Kim, Jung Mogg|Cha, Mi Yeon|Jung, Hyun Chae|Song, In Sung|Kim, Joo Sung
PMID: 22623043
Journal: Clin Cancer Res. 2012 Sep 15;18(18):4942-53.
Title: Ursolic acid inhibits growth and metastasis of human colorectal cancer in an orthotopic nude mouse model by targeting multiple cell signaling pathways: chemosensitization with capecitabine.
Author: Prasad, Sahdeo|Yadav, Vivek R|Sung, Bokyung|Reuter, Simone|Kannappan, Ramaswamy|Deorukhkar, Amit|Diagaradjane, Parmeswaran|Wei, Caimiao|Baladandayuthapani, Veerabhadran|Krishnan, Sunil|Guha, Sushovan|Aggarwal, Bharat B
PMID: 22832932
Journal: Cancer Res. 2012 Nov 15;72(22):5778-89.
Title: Prohibitin attenuates colitis-associated tumorigenesis in mice by modulating p53 and STAT3 apoptotic responses.
Author: Kathiria, Arwa S|Neumann, William L|Rhees, Jennifer|Hotchkiss, Erin|Cheng, Yulan|Genta, Robert M|Meltzer, Stephen J|Souza, Rhonda F|Theiss, Arianne L
PMID: 22869582
Journal: Cell Cycle. 2012 Sep 1;11(17):3312-23.
Title: Mitomycin C potentiates TRAIL-induced apoptosis through p53-independent upregulation of death receptors: evidence for the role of c-Jun N-terminal kinase activation.
Author: Cheng, Hairong|Hong, Bo|Zhou, Lanlan|Allen, Joshua E|Tai, Guihua|Humphreys, Robin|Dicker, David T|Liu, Yingqiu Y|El-Deiry, Wafik S
PMID: 22895172
Journal: Life Sci. 2012 Oct 22;91(15-16):789-99.
Title: AEE788 potentiates celecoxib-induced growth inhibition and apoptosis in human colon cancer cells.
Author: Venkatesan, P|Bhutia, Sujit K|Singh, Abhay K|Das, Swadesh K|Dash, Rupesh|Chaudhury, Koel|Sarkar, Devanand|Fisher, Paul B|Mandal, Mahitosh
PMID: 22922496
Journal: Int J Mol Sci. 2012;13(7):9184-93.
Title: Effect of beta,beta-dimethylacrylshikonin on inhibition of human colorectal cancer cell growth in vitro and in vivo.
Author: Fan, Yingying|Jin, Shaoju|He, Jun|Shao, Zhenjun|Yan, Jiao|Feng, Ting|Li, Hong
PMID: 22942759
Journal: J Biol Chem. 2012 Nov 9;287(46):39193-204.
Title: Cyclin-dependent kinase-1 (Cdk1)/cyclin B1 dictates cell fate after mitotic arrest via phosphoregulation of antiapoptotic Bcl-2 proteins.
Author: Sakurikar, Nandini|Eichhorn, Joshua M|Chambers, Timothy C
PMID: 22965228
Journal: Mol Cancer Res. 2012 Dec;10(12):1567-79.
Title: The role of Bcl-xL in synergistic induction of apoptosis by mapatumumab and oxaliplatin in combination with hyperthermia on human colon cancer.
Author: Song, Xinxin|Kim, Seog-Young|Lee, Yong J
PMID: 23051936
Journal: J Gene Med. 2012 Dec;14(12):761-8.
Title: Suppressing the growth of rectal cancer xenografts derived from patient tumors by an adenovector expressing small hairpin RNA targeting Bcl-XL.
Author: Zhu, Hongbo|Zhou, Wei|Hu, Jingzi|Huang, Zhongting|Lao, Weifeng|Huang, Xuefeng|He, Chao
PMID: 23169477
Journal: Oncol Res. 2012;20(2-3):81-91.
Title: Quinacrine-mediated autophagy and apoptosis in colon cancer cells is through a p53- and p21-dependent mechanism.
Author: Mohapatra, Purusottam|Preet, Ranjan|Das, Dipon|Satapathy, Shakti Ranjan|Choudhuri, Tathagata|Wyatt, Michael D|Kundu, Chanakya Nath
PMID: 23193914
Journal: Zhonghua Wai Ke Za Zhi. 2012 Oct;50(10):914-7.
Title: [Detection and clinical significance of apoptosis related protein in local advanced rectal cancer patients with preoperative neoadjuvant therapy].
Author: Liu, Yong|Zhang, Gu|Qian, Jun|Zhu, Yu-ping|Ju, Hai-xing|Feng, Hai-yang|Zhu, Hui-neng|Li, De-chuan
PMID: 23302463
Journal: Oncogene. 2013 Jun 6;32(23):2873-81.
Title: Oncogenic RAS simultaneously protects against anti-EGFR antibody-dependent cellular cytotoxicity and EGFR signaling blockade.
Author: Kasper, S|Breitenbuecher, F|Reis, H|Brandau, S|Worm, K|Kohler, J|Paul, A|Trarbach, T|Schmid, K W|Schuler, M
PMID: 22797062
Journal: Oncogene. 2013 Jun 20;32(25):3071-9.
Title: MicroRNA-125b promotes apoptosis by regulating the expression of Mcl-1, Bcl-w and IL-6R.
Author: Gong, J|Zhang, J-P|Li, B|Zeng, C|You, K|Chen, M-X|Yuan, Y|Zhuang, S-M
PMID: 22824797
Journal: Oncol Rep. 2013 Feb;29(2):474-80.
Title: Casticin, a flavonoid, potentiates TRAIL-induced apoptosis through modulation of anti-apoptotic proteins and death receptor 5 in colon cancer cells.
Author: Tang, San-Yuan|Zhong, Mei-Zuo|Yuan, Guang-Jin|Hou, Su-Ping|Yin, Lei-Lan|Jiang, Hao|Yu, Zheng-Upsilonang
PMID: 23135489
Journal: Tumour Biol. 2013 Apr;34(2):683-93.
Title: Upregulation of the antiapoptotic factor Livin contributes to cisplatin resistance in colon cancer cells.
Author: Ding, Zhen-Yu|Liu, Gui-Hong|Olsson, Birgit|Sun, Xiao-Feng
PMID: 23188704
Journal: Mol Cancer Res. 2013 Feb;11(2):109-21.
Title: Knockdown of PAK4 or PAK1 inhibits the proliferation of mutant KRAS colon cancer cells independently of RAF/MEK/ERK and PI3K/AKT signaling.
Author: Tabusa, Hana|Brooks, Teresa|Massey, Andrew J
PMID: 23233484
Journal: Oncol Rep. 2013 Mar;29(3):1245-51.
Title: T-18, a stemonamide synthetic intermediate inhibits Pim kinase activity and induces cell apoptosis, acting as a potent anticancer drug.
Author: Wang, Zhen|Li, Xing-Min|Shang, Kun|Zhang, Peng|Wang, Chao-Fu|Xin, Yu-Hu|Zhou, Lu|Li, Ying-Yi
PMID: 23314349
Journal: RNA Biol. 2013 Feb;10(2):287-300.
Title: Large-scale screening identifies a novel microRNA, miR-15a-3p, which induces apoptosis in human cancer cell lines.
Author: Druz, Aliaksandr|Chen, Yu-Chi|Guha, Rajarshi|Betenbaugh, Michael|Martin, Scott E|Shiloach, Joseph
PMID: 23353574
Journal: Cell Physiol Biochem. 2013;31(1):113-22.
Title: External Qi of Yan Xin Qigong inhibits activation of Akt, Erk1/2 and NF-kB and induces cell cycle arrest and apoptosis in colorectal cancer cells.
Author: Yan, Xin|Shen, Hua|Jiang, Hongjian|Hu, Dan|Wang, Jun|Wu, Xinqi
PMID: 23363659
Journal: BMC Cancer. 2013 Feb 5;13:59.
Title: IL-22 is related to development of human colon cancer by activation of STAT3.
Author: Jiang, Runqiu|Wang, Haiyang|Deng, Lei|Hou, Jiajie|Shi, Ruihua|Yao, Ming|Gao, Yun|Yao, Aihua|Wang, Xuehao|Yu, Lianzhen|Sun, Beicheng
PMID: 23379788
Journal: PLoS One. 2013;8(2):e57218.
Title: Curcumin enhances the effect of chemotherapy against colorectal cancer cells by inhibition of NF-kappaB and Src protein kinase signaling pathways.
Author: Shakibaei, Mehdi|Mobasheri, Ali|Lueders, Cora|Busch, Franziska|Shayan, Paviz|Goel, Ajay
PMID: 23451189
Journal: Nanomedicine (Lond). 2013 Aug;8(8):1307-22.
Title: Silver-based nanoparticles induce apoptosis in human colon cancer cells mediated through p53.
Author: Satapathy, Shakti Ranjan|Mohapatra, Purusottam|Preet, Ranjan|Das, Dipon|Sarkar, Biplab|Choudhuri, Tathagata|Wyatt, Michael D|Kundu, Chanakya Nath
PMID: 23514434
Journal: Mol Cancer. 2013 May 16;12(1):42.
Title: The novel BH3 alpha-helix mimetic JY-1-106 induces apoptosis in a subset of cancer cells (lung cancer, colon cancer and mesothelioma) by disrupting Bcl-xL and Mcl-1 protein-protein interactions with Bak.
Author: Cao, Xiaobo|Yap, Jeremy L|Newell-Rogers, M Karen|Peddaboina, Chander|Jiang, Weihua|Papaconstantinou, Harry T|Jupitor, Dan|Rai, Arun|Jung, Kwan-Young|Tubin, Richard P|Yu, Wenbo|Vanommeslaeghe, Kenno|Wilder, Paul T|MacKerell, Alexander D Jr|Fletcher, Steven
PMID: 23680104
Journal: Free Radic Biol Med. 2013 Oct;63:280-90.
Title: Aldose reductase inhibition enhances TRAIL-induced human colon cancer cell apoptosis through AKT/FOXO3a-dependent upregulation of death receptors.
Author: Shoeb, Mohammad|Ramana, Kota V|Srivastava, Satish K
PMID: 23732517
Journal: PLoS One. 2013 Jun 11;8(6):e65745.
Title: 2-deprenyl-rheediaxanthone B isolated from Metaxya rostrata induces active cell death in colorectal tumor cells.
Author: Kainz, Kerstin P|Krenn, Liselotte|Erdem, Zeynep|Kaehlig, Hanspeter|Zehl, Martin|Bursch, Wilfried|Berger, Walter|Marian, Brigitte
PMID: 23776538
Journal: Evid Based Complement Alternat Med. 2013;2013:987612.
Title: HSP90 Inhibitors, Geldanamycin and Radicicol, Enhance Fisetin-Induced Cytotoxicity via Induction of Apoptosis in Human Colonic Cancer Cells.
Author: Wu, Ming-Shun|Lien, Gi-Shih|Shen, Shing-Chuan|Yang, Liang-Yo|Chen, Yen-Chou
PMID: 23840275
Journal: Cancer Cell Int. 2013 Jul 12;13(1):69.
Title: Inhibition of the angiogenesis and growth of Aloin in human colorectal cancer in vitro and in vivo.
Author: Pan, Qin|Pan, Hongming|Lou, Haizhou|Xu, Yinghua|Tian, Lu
PMID: 23848964
Journal: Apoptosis. 2013 Oct;18(10):1163-74.
Title: Gamma-secretase inhibition attenuates oxaliplatin-induced apoptosis through increased Mcl-1 and/or Bcl-xL in human colon cancer cells.
Author: Timme, Cindy R|Gruidl, Mike|Yeatman, Timothy J
PMID: 23887890
Journal: J Biol Chem. 2013 Oct 4;288(40):28713-26.
Title: The natural compound cantharidin induces cancer cell death through inhibition of heat shock protein 70 (HSP70) and Bcl-2-associated athanogene domain 3 (BAG3) expression by blocking heat shock factor 1 (HSF1) binding to promoters.
Author: Kim, Joo Ae|Kim, Youngmi|Kwon, Byoung-Mog|Han, Dong Cho
PMID: 23983126
Journal: Mol Cells. 2013 Sep;36(3):219-26.
Title: Midazolam induces cellular apoptosis in human cancer cells and inhibits tumor growth in xenograft mice.
Author: Mishra, Siddhartha Kumar|Kang, Ju-Hee|Lee, Chang Woo|Oh, Seung Hyun|Ryu, Jun Sun|Bae, Yun Soo|Kim, Hwan Mook
PMID: 24008365
Journal: PLoS One. 2013 Aug 27;8(8):e73654.
Title: Evidence for two modes of synergistic induction of apoptosis by mapatumumab and oxaliplatin in combination with hyperthermia in human colon cancer cells.
Author: Song, Xinxin|Kim, Seog-Young|Lee, Yong J
PMID: 24013390
Journal: Cell Death Dis. 2013 Sep 12;4:e801.
Title: Metastatic SW620 colon cancer cells are primed for death when detached and can be sensitized to anoikis by the BH3-mimetic ABT-737.
Author: Maamer-Azzabi, A|Ndozangue-Touriguine, O|Breard, J
PMID: 24030153
Journal: Toxicol In Vitro. 2013 Dec;27(8):2127-34.
Title: Different susceptibility of colon cancer DLD-1 and LOVO cell lines to apoptosis induced by DMU-212, a synthetic resveratrol analogue.
Author: Piotrowska, Hanna|Myszkowski, Krzysztof|Amarowicz, Ryszard|Murias, Marek|Kulcenty, Katarzyna|Wierzchowski, Marcin|Jodynis-Liebert, Jadwiga
PMID: 24055891
Journal: Zhongguo Zhong Yao Za Zhi. 2013 Jul;38(13):2191-6.
Title: [Study on functions and mechanism of curcumin in inducing colorectal carcinoma cells LoVo apoptosis].
Author: Guo, Li-Da|Jiao, Zhen-Xia|Song, Ying|Teng, Wen-Hua|Liu, Zhao|Liu, Jing-Ze
PMID: 24079252
Journal: PLoS One. 2013 Oct 3;8(10):e76446.
Title: Beyond cell death - antiapoptotic Bcl-2 proteins regulate migration and invasion of colorectal cancer cells in vitro.
Author: Koehler, Bruno Christian|Scherr, Anna-Lena|Lorenz, Stephan|Urbanik, Toni|Kautz, Nicole|Elssner, Christin|Welte, Stefan|Bermejo, Justo Lorenzo|Jager, Dirk|Schulze-Bergkamen, Henning
PMID: 24098503
Journal: J Drug Target. 2013 Nov 13.
Title: Characterization of oleanolic acid derivative for colon cancer targeting with positron emission tomography.
Author: Kim, Sung-Min|Jeong, Il Ha|Yim, Min Su|Chae, Min Kyung|Kim, Hak Nam|Kim, Dong Kue|Kang, Choong Mo|Choe, Yearn Seong|Lee, Chulhyun|Ryu, Eun Kyoung
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Journal: Int J Mol Sci. 2013 Dec 2;14(12):23545-58.
Title: Pro-apoptotic effect of rice bran inositol hexaphosphate (IP6) on HT-29 colorectal cancer cells.
Author: Shafie, Nurul Husna|Esa, Norhaizan Mohd|Ithnin, Hairuszah|Saad, Norazalina|Pandurangan, Ashok Kumar
PMID: 24317430
Journal: Cell Physiol Biochem. 2013;32(6):1587-99.
Title: ART1 silencing enhances apoptosis of mouse CT26 cells via the PI3K/Akt/NF-kappaB pathway.
Author: Xiao, Ming|Tang, Yi|Wang, Ya-Lan|Yang, Lian|Li, Xian|Kuang, Jing|Song, Guang-Lin
PMID: 24335275
Journal: Pharmacol Rep. 2013;65(5):1366-74.
Title: Inhibition of Wnt/beta-catenin signaling mediates ursolic acid-induced apoptosis in PC-3 prostate cancer cells.
Author: Park, Ji-Hyuk|Kwon, Hee-Young|Sohn, Eun Jung|Kim, Kyung A|Kim, Bonglee|Jeong, Soo-Jin|Song, Jun Ho|Koo, Jin Suk|Kim, Sung-Hoon
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Journal: Mol Med Rep. 2014 Jan;9(1):249-54.
Title: Berberine enhances chemosensitivity to irinotecan in colon cancer via inhibition of NFkappaB.
Author: Yu, Meiling|Tong, Xuhui|Qi, Benquan|Qu, Hongdang|Dong, Shuying|Yu, Binbin|Zhang, Naiju|Tang, Nan|Wang, Lingzhi|Zhang, Cuiling
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Journal: J Ethnopharmacol. 2014;151(1):292-8.
Title: Total alkaloids of Tripterygium hypoglaucum (levl.) Hutch inhibits tumor growth both in vitro and in vivo.
Author: Jiang, Xiao|Huang, Xiao-chun|Ao, Lin|Liu, Wen-bin|Han, Fei|Cao, Jia|Zhang, Dong-yun|Huang, Chuan-shu|Liu, Jin-Yi
PMID: 24212079
Journal: J Surg Oncol. 2014 Mar;109(3):255-65.
Title: Expression of apoptosis regulating proteins identifies stage II and III colon cancer patients with high risk of recurrence.
Author: Belt, Eric J Th|Stockmann, Hein B A C|Delis-van Diemen, Pien M|Bril, Herman|Tijssen, Marianne|van Essen, Hendrik F|Heymans, Martijn W|Belien, Jeroen A M|Carvalho, Beatriz|Cillessen, Saskia A G M|Meijer, Gerrit A
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Journal: Immunity. 2014 Jan 16;40(1):140-52.
Title: Alterations in the microbiota drive interleukin-17C production from intestinal epithelial cells to promote tumorigenesis.
Author: Song, Xinyang|Gao, Hanchao|Lin, Yingying|Yao, Yikun|Zhu, Shu|Wang, Jingjing|Liu, Yan|Yao, Xiaomin|Meng, Guangxun|Shen, Nan|Shi, Yufang|Iwakura, Yoichiro|Qian, Youcun
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Journal: Int J Oncol. 2014 Apr;44(4):1309-15.
Title: Carnosol induces apoptosis through generation of ROS and inactivation of STAT3 signaling in human colon cancer HCT116 cells.
Author: Park, Ki-Woong|Kundu, Juthika|Chae, In-Gyeong|Kim, Do-Hee|Yu, Mi-Hee|Kundu, Joydeb Kumar|Chun, Kyung-Soo
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Journal: J Pineal Res. 2014 Apr;56(3):264-74.
Title: Melatonin treatment induces interplay of apoptosis, autophagy, and senescence in human colorectal cancer cells.
Author: Hong, Yunkyung|Won, Jinyoung|Lee, Youngjeon|Lee, Seunghoon|Park, Kanghui|Chang, Kyu-Tae|Hong, Yonggeun
PMID: 24484372
Journal: Biochem Pharmacol. 2014 Mar 15;88(2):178-88.
Title: Role of Bcl-xL/Beclin-1 in interplay between apoptosis and autophagy in oxaliplatin and bortezomib-induced cell death.
Author: Kim, Seog-Young|Song, Xinxin|Zhang, Lin|Bartlett, David L|Lee, Yong J
PMID: 24486574
Journal: Exp Cell Res. 2014 Apr 1;322(2):415-24.
Title: Molecular analysis of functional redundancy among anti-apoptotic Bcl-2 proteins and its role in cancer cell survival.
Author: Eichhorn, Joshua M|Alford, Sarah E|Sakurikar, Nandini|Chambers, Timothy C
PMID: 24556425
Journal: World J Gastroenterol. 2014 Feb 7;20(5):1305-10.
Title: Bax protein may influence the invasion of colorectal cancer.
Author: Pryczynicz, Anna|Gryko, Mariusz|Niewiarowska, Katarzyna|Cepowicz, Dariusz|Ustymowicz, Marek|Kemona, Andrzej|Guzinska-Ustymowicz, Katarzyna
PMID: 24574804
Journal: Cell Death Differ. 2014 Jul;21(7):1170-7.
Title: Decreased mitochondrial priming determines chemoresistance of colon cancer stem cells.
Author: Colak, S|Zimberlin, C D|Fessler, E|Hogdal, L|Prasetyanti, P R|Grandela, C M|Letai, A|Medema, J P
PMID: 24682005
Journal: Am J Chin Med. 2014;42(2):465-83.
Title: Flavonoids identified from Korean Scutellaria baicalensis induce apoptosis by ROS generation and caspase activation on human fibrosarcoma cells.
Author: Zhang, Jue|Park, Hyeon-Soo|Kim, Jin-A|Hong, Gyeong-Eun|Nagappan, Arulkumar|Park, Kwang-Il|Kim, Gon-Sup
PMID: 24707875
Journal: Int J Mol Med. 2014 Jul;34(1):35-42.
Title: LGR5 is required for the maintenance of spheroid-derived colon cancer stem cells.
Author: Chen, Xiang|Wei, Bo|Han, Xiaoyan|Zheng, Zongheng|Huang, Jianglong|Liu, Jianpei|Huang, Yong|Wei, Hongbo
PMID: 24789370
Journal: Chem Biol Interact. 2014 Jul 25;218:42-9.
Title: Induction of ROS-independent JNK-activation-mediated apoptosis by a novel coumarin-derivative, DMAC, in human colon cancer cells.
Author: Lin, Mei-Hsiang|Cheng, Chia-Hsiung|Chen, Ku-Chung|Lee, Wai-Theng|Wang, Yen-Fang|Xiao, Cai-Qin|Lin, Cheng-Wei
PMID: 24812029
Journal: Mar Drugs. 2014 May 22;12(5):3072-90.
Title: Cracking the cytotoxicity code: apoptotic induction of 10-acetylirciformonin B is mediated through ROS generation and mitochondrial dysfunction.
Author: Shih, Huei-Chuan|El-Shazly, Mohamed|Juan, Yung-Shun|Chang, Chao-Yuan|Su, Jui-Hsin|Chen, Yu-Cheng|Shih, Shou-Ping|Chen, Huei-Mei|Wu, Yang-Chang|Lu, Mei-Chin
PMID: 24857964
Journal: Oncol Rep. 2014 Aug;32(2):821-8.
Title: Thymoquinone induces apoptosis in human colon cancer HCT116 cells through inactivation of STAT3 by blocking JAK2- and Srcmediated phosphorylation of EGF receptor tyrosine kinase.
Author: Kundu, Juthika|Choi, Bu Young|Jeong, Chul-Ho|Kundu, Joydeb Kumar|Chun, Kyung-Soo
PMID: 24890449
Journal: PLoS One. 2014 Jun 3;9(6):e96767.
Title: Functional screening identifies miRNAs influencing apoptosis and proliferation in colorectal cancer.
Author: Christensen, Lise Lotte|Holm, Anja|Rantala, Juha|Kallioniemi, Olli|Rasmussen, Mads H|Ostenfeld, Marie S|Dagnaes-Hansen, Frederik|Oster, Bodil|Schepeler, Troels|Tobiasen, Heidi|Thorsen, Kasper|Sieber, Oliver M|Gibbs, Peter|Lamy, Philippe|Hansen, Torben F|J
PMID: 24892549
Journal: Food Chem Toxicol. 2014 Sep;71:51-9.
Title: Ilimaquinone induces death receptor expression and sensitizes human colon cancer cells to TRAIL-induced apoptosis through activation of ROS-ERK/p38 MAPK-CHOP signaling pathways.
Author: Do, Minh Truong|Na, MinKyun|Kim, Hyung Gyun|Khanal, Tilak|Choi, Jae Ho|Jin, Sun Woo|Oh, Seok Hoon|Hwang, In Hyun|Chung, Young Chul|Kim, Hee Suk|Jeong, Tae Cheon|Jeong, Hye Gwang
PMID: 24930757
Journal: Pathol Res Pract. 2014 Sep;210(9):576-81.
Title: Expression of apoptotic proteins in human colorectal cancer and metastatic lymph nodes.
Author: Sadowska, Anna|Car, Halina|Pryczynicz, Anna|Guzinska-Ustymowicz, Katarzyna|Kowal, Krzysztof Wojciech|Cepowicz, Dariusz|Kedra, Boguslaw
PMID: 24939147
Journal: Tumour Biol. 2014 Oct;35(10):9967-75.
Title: Benzylidenetetralones, cyclic chalcone analogues, induce cell cycle arrest and apoptosis in HCT116 colorectal cancer cells.
Author: Drutovic, David|Chripkova, Martina|Pilatova, Martina|Kruzliak, Peter|Perjesi, Pal|Sarissky, Marek|Lupi, Monica|Damia, Giovanna|Broggini, Massimo|Mojzis, Jan
PMID: 25008568
Journal: BMC Complement Altern Med. 2014 Jul 24;14:264.
Title: Cytotoxicity of Eupatorium cannabinum L. ethanolic extract against colon cancer cells and interactions with Bisphenol A and Doxorubicin.
Author: Ribeiro-Varandas, Edna|Ressurreicao, Filipe|Viegas, Wanda|Delgado, Margarida
PMID: 25056133
Journal: J Nat Prod. 2014 Aug 22;77(8):1825-30.
Title: 6-Acetonyldihydrochelerythrine Is a Potent Inducer of Apoptosis in HCT116 and SW620 Colon Cancer Cells.
Author: Mansoor, Tayyab A|Borralho, Pedro M|Luo, Xuan|Mulhovo, Silva|Rodrigues, Cecilia M P|Ferreira, Maria-Jose U
PMID: 25066282
Journal: Free Radic Res. 2014 Nov;48(11):1311-21.
Title: Generation of ROS by CAY10598 leads to inactivation of STAT3 signaling and induction of apoptosis in human colon cancer HCT116 cells.
Author: Chae, I G|Kim, D-H|Kundu, J|Jeong, C-H|Kundu, J K|Chun, K-S
PMID: 25096910
Journal: BMC Cancer. 2014 Aug 18;14:599.
Title: Variable NF-kappaB pathway responses in colon cancer cells treated with chemotherapeutic drugs.
Author: Samuel, Temesgen|Fadlalla, Khalda|Gales, Dominique N|Putcha, Balananda D K|Manne, Upender
PMID: 25134433
Journal: Apoptosis. 2014 Nov;19(11):1603-15.
Title: Role of Bcl-xL/Beclin-1 in synergistic apoptotic effects of secretory TRAIL-armed adenovirus in combination with mitomycin C and hyperthermia on colon cancer cells.
Author: Kim, Seog-Young|Lee, Dae-Hee|Song, Xinxin|Bartlett, David L|Kwon, Yong Tae|Lee, Yong J
PMID: 25156145
Journal: Cancer Res. 2014 Nov 1;74(21):6119-28.
Title: Stress response protein cirp links inflammation and tumorigenesis in colitis-associated cancer.
Author: Sakurai, Toshiharu|Kashida, Hiroshi|Watanabe, Tomohiro|Hagiwara, Satoru|Mizushima, Tsunekazu|Iijima, Hideki|Nishida, Naoshi|Higashitsuji, Hiroaki|Fujita, Jun|Kudo, Masatoshi
PMID: 25187386
Journal: PLoS One. 2014 Sep 5;9(9):e106571.
Title: Pan-Bcl-2 inhibitor obatoclax delays cell cycle progression and blocks migration of colorectal cancer cells.
Author: Koehler, Bruno Christian|Scherr, Anna-Lena|Lorenz, Stephan|Elssner, Christin|Kautz, Nicole|Welte, Stefan|Jaeger, Dirk|Urbanik, Toni|Schulze-Bergkamen, Henning
PMID: 25192188
Journal: PLoS One. 2014 Sep 8;9(9):e107165.
Title: EGFR-targeted TRAIL and a Smac mimetic synergize to overcome apoptosis resistance in KRAS mutant colorectal cancer cells.
Author: Moller, Yvonne|Siegemund, Martin|Beyes, Sven|Herr, Ricarda|Lecis, Daniele|Delia, Domenico|Kontermann, Roland|Brummer, Tilman|Pfizenmaier, Klaus|Olayioye, Monilola A
PMID: 25198428
Journal: Asian Pac J Cancer Prev. 2014;15(17):7291-6.
Title: Methanol extract of Flacourtia indica aerial parts induces apoptosis via generation of ROS and activation of caspases in human colon cancer HCT116 cells.
Author: Park, Ki-Woong|Kundu, Juthika|Chae, In Gyeong|Bachar, Sitesh Chandra|Bae, Jung-Woo|Chun, Kyung-Soo
PMID: 25227831
Journal: Biochimie. 2014 Dec;107 Pt B:310-8.
Title: Synergistic association of Notch and NFkappaB signaling and role of Notch signaling in modulating epithelial to mesenchymal transition in colorectal adenocarcinoma.
Author: Gopalakrishnan, Natarajan|Sivasithamparam, Niranjali Devaraj|Devaraj, Halagowder
PMID: 25257945
Journal: Cancer Lett. 2014 Dec 28;355(2):253-63.
Title: Clitocine induces apoptosis and enhances the lethality of ABT-737 in human colon cancer cells by disrupting the interaction of Mcl-1 and Bak.
Author: Sun, Jian-guo|Xiang, Jun|Zeng, Xue-li|Li, Xia|Wu, Ping|Fung, Kwok Pui|Liu, Fei-yan
PMID: 25304383
Journal: BMC Complement Altern Med. 2014 Oct 24;14:412.
Title: Hederagenin from the leaves of ivy (Hedera helix L.) induces apoptosis in human LoVo colon cells through the mitochondrial pathway.
Author: Liu, Bao-Xin-Zi|Zhou, Jin-Yong|Li, Yu|Zou, Xi|Wu, Jian|Gu, Jun-Fei|Yuan, Jia-Rui|Zhao, Bing-Jie|Feng, Liang|Jia, Xiao-Bin|Wang, Rui-Ping
PMID: 25342273
Journal: World J Gastroenterol. 2014 Nov 7;20(41):15275-88.
Title: Differential control of growth, apoptotic activity and gene expression in human colon cancer cells by extracts derived from medicinal herbs, Rhazya stricta and Zingiber officinale and their combination.
Author: Elkady, Ayman I|Hussein, Rania Abd El Hamid|Abu-Zinadah, Osama A
PMID: 25386076
Journal: Cancer Biol Ther. 2014;15(12):1646-57.
Title: Regulation of dimethyl-fumarate toxicity by proteasome inhibitors.
Author: Booth, Laurence|Cruickshanks, Nichola|Tavallai, Seyedmehrad|Roberts, Jane L|Peery, Matthew|Poklepovic, Andrew|Dent, Paul
PMID: 25482938
Journal: J BUON. 2014 Oct-Dec;19(4):925-9.
Title: Effect of Bcl-xL gene expression silenced by RNA interference on invasion of human colorectal cancer cells.
Author: Liu, Wei-Dong|Bo, Yan-Zhi|Fan, Yu|Wu, Kun|Gao, Cheng-Cheng|Xia, Tian-Fang|Qing, Zhen-Shen|Pang, Li-Qun
PMID: 25536597
Journal: J Cell Biochem. 2015 Feb;116(2):277-86.
Title: Decreased expression of heat shock protein 20 in colorectal cancer and its implication in tumorigenesis.
Author: Ju, Young-Tae|Kwag, Seung-Jin|Park, Hee Jin|Jung, Eun-Jung|Jeong, Chi-Young|Jeong, Sang-Ho|Lee, Young-Joon|Choi, Sang-Kyung|Kang, Kee Ryeon|Hah, Young-Sool|Hong, Soon-Chan
PMID: 25187324
Journal: Int J Oncol. 2015 Jan;46(1):113-22.
Title: Downregulation of thymidylate synthase and E2F1 by arsenic trioxide in mesothelioma.
Author: Lam, Sze-Kwan|Li, Yuan-Yuan|Zheng, Chun-Yan|Ho, James Chung-Man
PMID: 25335113
Journal: J Mol Med (Berl). 2015 Mar;93(3):315-26.
Title: BCL2 protein signalling determines acute responses to neoadjuvant chemoradiotherapy in rectal cancer.
Author: Flanagan, L|Lindner, A U|de Chaumont, C|Kehoe, J|Fay, J|Bacon, O|Toomey, S|Huber, H J|Hennessy, B T|Kay, E W|McNamara, D A|Prehn, J H M
PMID: 25388617
Journal: Tumour Biol. 2015 May;36(5):3447-55.
Title: The small-molecule compound BM-1197 inhibits the antiapoptotic regulators Bcl-2/Bcl-xL and triggers apoptotic cell death in human colorectal cancer cells.
Author: Ye, Lijun|Yuan, Gang|Xu, Fei|Sun, Yueli|Chen, Ziyan|Chen, Miaohong|Li, Tianxiao|Sun, Pingping|Li, Shuxia|Sun, Jian
PMID: 25542230
Journal: Mol Cancer Res. 2015 Apr;13(4):659-69.
Title: Reversal of Mutant KRAS-Mediated Apoptosis Resistance by Concurrent Noxa/Bik Induction and Bcl-2/Bcl-xL Antagonism in Colon Cancer Cells.
Author: Okamoto, Koichi|Zaanan, Aziz|Kawakami, Hisato|Huang, Shengbing|Sinicrope, Frank A
PMID: 25548100
Journal: Cancer Lett. 2015 Jul 28;363(2):119-26.
Title: Thioredoxin-like protein 2b facilitates colon cancer cell proliferation and inhibits apoptosis via NF-kappaB pathway.
Author: Lu, Yuanyuan|Zhao, Xiaodi|Luo, Guanhong|Shen, Gaofei|Li, Kai|Ren, Gui|Pan, Yan|Wang, Xin|Fan, Daiming
PMID: 25555669
Journal: Oncotarget. 2015 Jan 1;6(1):409-26.
Title: Irinotecan treatment and senescence failure promote the emergence of more transformed and invasive cells that depend on anti-apoptotic Mcl-1.
Author: Jonchere, Barbara|Vetillard, Alexandra|Toutain, Bertrand|Lam, David|Bernard, Anne Charlotte|Henry, Cecile|De Carne Trecesson, Sophie|Gamelin, Erick|Juin, Philippe|Guette, Catherine|Coqueret, Olivier
PMID: 25565667
Journal: Lipids. 2015 Mar;50(3):227-39.
Title: miRNA expression in human intestinal Caco-2 cells is comparably regulated by cis- and trans-fatty acids.
Author: Kopke, Solveigh|Buhrke, Thorsten|Lampen, Alfonso
PMID: 25612549
Journal: BMC Complement Altern Med. 2015 Feb 5;15:15.
Title: Inhibitory effect of Curcuma purpurascens BI. rhizome on HT-29 colon cancer cells through mitochondrial-dependent apoptosis pathway.
Author: Rouhollahi, Elham|Zorofchian Moghadamtousi, Soheil|Paydar, Mohammadjavad|Fadaeinasab, Mehran|Zahedifard, Maryam|Hajrezaie, Maryam|Ahmed Hamdi, Omer Abdalla|Looi, Chung Yeng|Abdulla, Mahmood Ameen|Awang, Khalijah|Mohamed, Zahurin
PMID: 25652758
Journal: Oncogene. 2015 Oct 1;34(40):5187-97.
Title: MUC1-C activates the TAK1 inflammatory pathway in colon cancer.
Author: Takahashi, H|Jin, C|Rajabi, H|Pitroda, S|Alam, M|Ahmad, R|Raina, D|Hasegawa, M|Suzuki, Y|Tagde, A|Bronson, R T|Weichselbaum, R|Kufe, D
PMID: 25659581
Journal: World J Gastroenterol. 2015 Feb 14;21(6):1804-13.
Title: Overexpression of B7-H3 augments anti-apoptosis of colorectal cancer cells by Jak2-STAT3.
Author: Zhang, Ting|Jiang, Bo|Zou, Shi-Tao|Liu, Fen|Hua, Dong
PMID: 25684945
Journal: Autophagy. 2015;11(3):452-9.
Title: BAX and BAK1 are dispensable for ABT-737-induced dissociation of the BCL2-BECN1 complex and autophagy.
Author: Pedro, Jose Manuel Bravo-San|Wei, Yongjie|Sica, Valentina|Maiuri, Maria Chiara|Zou, Zhongju|Kroemer, Guido|Levine, Beth
PMID: 25715028
Journal: Oncotarget. 2015 Mar 30;6(9):7084-103.
Title: Autophagy-based survival prognosis in human colorectal carcinoma.
Author: Yang, Maopeng|Zhao, Hong|Guo, Li|Zhang, Qingyuan|Zhao, Ling|Bai, Shuping|Zhang, Minghui|Xu, Sanqi|Wang, Fujing|Wang, Xiaohong|Zhao, Bin
PMID: 25762626
Journal: Cell Physiol Biochem. 2015;35(5):1821-30.
Title: Cinnamaldehyde derivative (CB-PIC) sensitizes chemo-resistant cancer cells to drug-induced apoptosis via suppression of MDR1 and its upstream STAT3 and AKT signalling.
Author: Yun, Miyong|Lee, Duckgue|Park, Moon-Nyeo|Kim, Eun-Ok|Sohn, Eun Jung|Kwon, Byung-Mog|Kim, Sung-Hoon
PMID: 25833196
Journal: Nutr J. 2015 Apr 1;14:31.
Title: Combined ginger extract & Gelam honey modulate Ras/ERK and PI3K/AKT pathway genes in colon cancer HT29 cells.
Author: Tahir, Analhuda Abdullah|Sani, Nur Fathiah Abdul|Murad, Noor Azian|Makpol, Suzana|Ngah, Wan Zurinah Wan|Yusof, Yasmin Anum Mohd
PMID: 25889965
Journal: J Nanobiotechnology. 2015 Mar 3;13:18.
Title: Biocompatible iota-carrageenan-gamma-maghemite nanocomposite for biomedical applications - synthesis, characterization and in vitro anticancer efficacy.
Author: Raman, Maya|Devi, Viswambari|Doble, Mukesh
PMID: 25890231
Journal: Int J Oncol. 2015 Aug;47(2):755-63.
Title: Acetylcarnitine potentiates the anticarcinogenic effects of butyrate on SW480 colon cancer cells.
Author: Elimrani, Ihsan|Dionne, Serge|Saragosti, Dan|Qureshi, Ijaz|Levy, Emile|Delvin, Edgar|Seidman, Ernest G
PMID: 26043725
Journal: BMC Gastroenterol. 2015 Jun 6;15:64.
Title: Gene expression profiling of laterally spreading tumors.
Author: Minemura, Shoko|Tanaka, Takeshi|Arai, Makoto|Okimoto, Kenichiro|Oyamada, Arata|Saito, Keiko|Maruoka, Daisuke|Matsumura, Tomoaki|Nakagawa, Tomoo|Katsuno, Tatsuro|Kishimoto, Takashi|Yokosuka, Osamu
PMID: 26048755
Journal: Mol Cancer. 2015 Jul 2;14:126.
Title: Genomic analysis and selective small molecule inhibition identifies BCL-X(L) as a critical survival factor in a subset of colorectal cancer.
Author: Zhang, Haichao|Xue, John|Hessler, Paul|Tahir, Stephen K|Chen, Jun|Jin, Sha|Souers, Andrew J|Leverson, Joel D|Lam, Lloyd T
PMID: 26134786
Journal: J Biol Chem. 2015 Sep 25;290(39):23838-49.
Title: The Mutant KRAS Gene Up-regulates BCL-XL Protein via STAT3 to Confer Apoptosis Resistance That Is Reversed by BIM Protein Induction and BCL-XL Antagonism.
Author: Zaanan, Aziz|Okamoto, Koichi|Kawakami, Hisato|Khazaie, Khashayarsha|Huang, Shengbing|Sinicrope, Frank A
PMID: 26245900
Journal: Eur J Med Chem. 2015 Sep 18;102:93-105.
Title: Synthesis and biological evaluation of a novel betulinic acid derivative as an inducer of apoptosis in human colon carcinoma cells (HT-29).
Author: Chakraborty, Biswajit|Dutta, Debasmita|Mukherjee, Sanjukta|Das, Supriya|Maiti, Nakul C|Das, Padma|Chowdhury, Chinmay
PMID: 26248310
Journal: Toxicol In Vitro. 2015 Dec;29(8):2009-14.
Title: Bisphenol A at the reference level counteracts doxorubicin transcriptional effects on cancer related genes in HT29 cells.
Author: Delgado, Margarida|Ribeiro-Varandas, Edna
PMID: 26320837
Journal: Mol Cancer Res. 2015 Dec;13(12):1533-43.
Title: Hypoxia Promotes Synergy between Mitomycin C and Bortezomib through a Coordinated Process of Bcl-xL Phosphorylation and Mitochondrial Translocation of p53.
Author: Song, Xinxin|Dilly, Ashok-Kumar|Choudry, Haroon Asif|Bartlett, David L|Kwon, Yong Tae|Lee, Yong J
PMID: 26354682
Journal: Am J Chin Med. 2015;43(7):1471-86.
Title: Ursolic Acid Induces Apoptosis of Prostate Cancer Cells via the PI3K/Akt/mTOR Pathway.
Author: Meng, Yan|Lin, Zhao-Min|Ge, Nan|Zhang, Deng-Lu|Huang, Jie|Kong, Feng
PMID: 26503559
Journal: Invest New Drugs. 2015 Dec;33(6):1175-86.
Title: Identification of a novel compound (beta-sesquiphellandrene) from turmeric (Curcuma longa) with anticancer potential: comparison with curcumin.
Author: Tyagi, Amit Kumar|Prasad, Sahdeo|Yuan, Wei|Li, Shiyou|Aggarwal, Bharat B
PMID: 26521943
Journal: Contemp Oncol (Pozn). 2015;19(4):261-4.
Title: The role of Reg IV in colorectal cancer, as a potential therapeutic target.
Author: Hu, Yiwang|Pan, Chi|Hu, Jiyi|Zhang, Suzhan
PMID: 26557771
Journal: Cancer Biol Ther. 2015;16(12):1710-9.
Title: Regorafenib with a fluoropyrimidine for metastatic colorectal cancer after progression on multiple 5-FU-containing combination therapies and regorafenib monotherapy.
Author: Marks, Eric I|Tan, Carlyn|Zhang, Jun|Zhou, Lanlan|Yang, Zhaohai|Scicchitano, Angelique|El-Deiry, Wafik S
PMID: 26561209
Journal: J Exp Clin Cancer Res. 2015 Nov 21;34:142.
Title: A-kinase anchor protein 4 (AKAP4) a promising therapeutic target of colorectal cancer.
Author: Jagadish, Nirmala|Parashar, Deepak|Gupta, Namita|Agarwal, Sumit|Purohit, Sapna|Kumar, Vikash|Sharma, Aditi|Fatima, Rukhsar|Topno, Amos Prashant|Shaha, Chandrima|Suri, Anil
PMID: 26590805
Journal: Gastroenterol Res Pract. 2015;2015:457193.
Title: Bufalin Inhibits HCT116 Colon Cancer Cells and Its Orthotopic Xenograft Tumor in Mice Model through Genes Related to Apoptotic and PTEN/AKT Pathways.
Author: Wang, Jie|Chen, Chao|Wang, Shiying|Zhang, Yong|Yin, Peihao|Gao, Zhongxiang|Xu, Jie|Feng, Dianxu|Zuo, Qinsong|Zhao, Ronghua|Chen, Teng
PMID: 26770191
Journal: Cell Cycle. 2016 Jun 17;15(12):1531-7.
Title: Human colonic fibroblasts regulate stemness and chemotherapy resistance of colon cancer stem cells.
Author: Colak, S|Medema, J P
PMID: 25483065
Journal: Environ Toxicol. 2016 Aug;31(8):957-69.
Title: Crude extract of Rheum palmatum L. Induces cell cycle arrest S phase and apoptosis through mitochondrial-dependent pathways in U-2 OS human osteosarcoma cells.
Author: Lin, Chin-Chung|Lee, Ming-Huei|Lin, Ju-Hwa|Lin, Meng-Liang|Chueh, Fu-Shin|Yu, Chien-Chih|Lin, Jing-Pin|Chou, Yu-Cheng|Hsu, Shu-Chun|Chung, Jing-Gung
PMID: 25689151
Journal: Mol Carcinog. 2016 Jun;55(6):1096-110.
Title: Carnosic acid inhibits STAT3 signaling and induces apoptosis through generation of ROS in human colon cancer HCT116 cells.
Author: Kim, Do-Hee|Park, Ki-Woong|Chae, In Gyeong|Kundu, Juthika|Kim, Eun-Hee|Kundu, Joydeb Kumar|Chun, Kyung-Soo
PMID: 26152521
Journal: Hum Exp Toxicol. 2016 May;35(5):526-43.
Title: Treatment with cucurbitacin B alone and in combination with gefitinib induces cell cycle inhibition and apoptosis via EGFR and JAK/STAT pathway in human colorectal cancer cell lines.
Author: Yar Saglam, A S|Alp, E|Elmazoglu, Z|Menevse, S
PMID: 26183715
Journal: Tumour Biol. 2016 May;37(5):6053-63.
Title: Regulatory effects of DeltaFosB on proliferation and apoptosis of MCF-7 breast cancer cells.
Author: Li, Hui|Li, Lihui|Zheng, Huiling|Yao, Xiaotong|Zang, Wenjuan
PMID: 26608367
Journal: Oncol Rep. 2016 Apr;35(4):2466-72.
Title: Knockdown of MACC1 expression increases cisplatin sensitivity in cisplatin-resistant epithelial ovarian cancer cells.
Author: Zhang, Ruitao|Shi, Huirong|Ren, Fang|Li, Xia|Zhang, Minghui|Feng, Wei|Jia, Yanyan
PMID: 26794135
Journal: PLoS One. 2016 Feb 9;11(2):e0148775.
Title: Flavokawain C Inhibits Cell Cycle and Promotes Apoptosis, Associated with Endoplasmic Reticulum Stress and Regulation of MAPKs and Akt Signaling Pathways in HCT 116 Human Colon Carcinoma Cells.
Author: Phang, Chung-Weng|Karsani, Saiful Anuar|Sethi, Gautam|Abd Malek, Sri Nurestri
PMID: 26859847
Journal: Chem Biol Interact. 2016 Apr 5;249:23-35.
Title: In vitro antiproliferative activity of 2,3-dihydroxy-9,10-anthraquinone induced apoptosis against COLO320 cells through cytochrome c release caspase mediated pathway with PI3K/AKT and COX-2 inhibition.
Author: Balachandran, C|Emi, N|Arun, Y|Yamamoto, N|Duraipandiyan, V|Inaguma, Yoko|Okamoto, Akinao|Ignacimuthu, S|Al-Dhabi, N A|Perumal, P T
PMID: 26915975
Journal: Life Sci. 2016 Apr 1;150:32-8.
Title: Chalcone derivatives cause accumulation of colon cancer cells in the G2/M phase and induce apoptosis.
Author: Kello, Martin|Drutovic, David|Pilatova, Martina Bago|Tischlerova, Vierka|Perjesi, Pal|Mojzis, Jan
PMID: 26916824
Journal: Oncotarget. 2016 Apr 19;7(16):22077-91.
Title: The TGF-beta pathway is activated by 5-fluorouracil treatment in drug resistant colorectal carcinoma cells.
Author: Romano, Gabriele|Santi, Ludovica|Bianco, Maria Rosaria|Giuffre, Maria Rita|Pettinato, Mariateresa|Bugarin, Cristina|Garanzini, Cristina|Savarese, Leonilde|Leoni, Silvia|Cerrito, Maria Grazia|Leone, Biagio Eugenio|Gaipa, Giuseppe|Grassilli, Emanuela|Papa,
PMID: 26956045
Journal: Oncol Rep. 2016 Jun;35(6):3363-70.
Title: Harmine induces cell cycle arrest and mitochondrial pathway-mediated cellular apoptosis in SW620 cells via inhibition of the Akt and ERK signaling pathways.
Author: Liu, Jiming|Li, Qiang|Liu, Zhilong|Lin, Liuming|Zhang, Xiangqiang|Cao, Mingrong|Jiang, Jianwei
PMID: 27004568
Journal: Pharmacogn Mag. 2016 Jan-Mar;12(45):25-30.
Title: Luffa echinata Roxb. Induced Apoptosis in Human Colon Cancer Cell (SW-480) in the Caspase-dependent Manner and Through a Mitochondrial Apoptosis Pathway.
Author: Shang, Li-Hua|Yu, Yan|Che, De-Hai|Pan, Bo|Jin, Shi|Zou, Xiao-Long
PMID: 27019558
Journal: BBA Clin. 2015 Nov 5;5:16-24.
Title: Inflammatory bowel disease, colorectal cancer and type 2 diabetes mellitus: The links.
Author: Jurjus, Abdo|Eid, Assad|Al Kattar, Sahar|Zeenny, Marie Noel|Gerges-Geagea, Alice|Haydar, Hanine|Hilal, Anis|Oueidat, Doreid|Matar, Michel|Tawilah, Jihane|Hussein, Inaya Hajj|Schembri-Wismayer, Pierre|Cappello, Francesco|Tomasello, Giovanni|Leone, Angelo|J
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Journal: Mol Ther. 2016 Aug;24(7):1199-215.
Title: CRNDE Promotes Malignant Progression of Glioma by Attenuating miR-384/PIWIL4/STAT3 Axis.
Author: Zheng, Jian|Liu, Xiaobai|Wang, Ping|Xue, Yixue|Ma, Jun|Qu, Chengbin|Liu, Yunhui
PMID: 27058823
Journal: Mol Cancer Res. 2016 Aug;14(8):753-63.
Title: JNK1 Inhibition Attenuates Hypoxia-Induced Autophagy and Sensitizes to Chemotherapy.
Author: Vasilevskaya, Irina A|Selvakumaran, Muthu|Roberts, David|O'Dwyer, Peter J
PMID: 27216154
Journal: Molecules. 2016 Jun 4;21(6). pii: molecules21060730.
Title: Dioscin Induces Apoptosis in Human Cervical Carcinoma HeLa and SiHa Cells through ROS-Mediated DNA Damage and the Mitochondrial Signaling Pathway.
Author: Zhao, Xinwei|Tao, Xufeng|Xu, Lina|Yin, Lianhong|Qi, Yan|Xu, Youwei|Han, Xu|Peng, Jinyong
PMID: 27271587
Journal: Acta Biomater. 2016 Sep 15;42:220-231.
Title: Engineering of caveolae-specific self-micellizing anticancer lipid nanoparticles to enhance the chemotherapeutic efficacy of oxaliplatin in colorectal cancer cells.
Author: Sundaramoorthy, Pasupathi|Ramasamy, Thiruganesh|Mishra, Siddhartha Kumar|Jeong, Keun-Yeong|Yong, Chul Soon|Kim, Jong Oh|Kim, Hwan Mook
PMID: 27395829
Journal: Molecules. 2016 Jul 19;21(7). pii: molecules21070934.
Title: Protocatechualdehyde Induces S-Phase Arrest and Apoptosis by Stimulating the p27(KIP1)-Cyclin A/D1-CDK2 and Mitochondrial Apoptotic Pathways in HT-29 Cells.
Author: Zhong, Shi|Li, You-Gui|Ji, Dong-Feng|Lin, Tian-Bao|Lv, Zhi-Qiang
PMID: 27447597
Journal: Protein Cell. 2016 Aug;7(8):571-85.
Title: Ursolic acid synergistically enhances the therapeutic effects of oxaliplatin in colorectal cancer.
Author: Shan, Jianzhen|Xuan, Yanyan|Zhang, Qi|Zhu, Chunpeng|Liu, Zhen|Zhang, Suzhan
PMID: 27472952
Journal: Cell Death Dis. 2016 Aug 18;7(8):e2342.
Title: Bcl-xL is an oncogenic driver in colorectal cancer.
Author: Scherr, Anna-Lena|Gdynia, Georg|Salou, Mariam|Radhakrishnan, Praveen|Duglova, Katarina|Heller, Anette|Keim, Sophia|Kautz, Nicole|Jassowicz, Adam|Elssner, Christin|He, You-Wen|Jaeger, Dirk|Heikenwalder, Mathias|Schneider, Martin|Weber, Achim|Roth, Wilfried
PMID: 27537525
Journal: Mol Ther Oncolytics. 2016 Aug 10;3:16020.
Title: N-end rule pathway inhibition assists colon tumor regression via necroptosis.
Author: Agarwalla, Pritha|Banerjee, Rajkumar
PMID: 27556106
Journal: Oncotarget. 2016 Sep 20;7(38):62474-62489.
Title: Long noncoding RNA CCAT1 acts as an oncogene and promotes chemoresistance in docetaxel-resistant lung adenocarcinoma cells.
Author: Chen, Jing|Zhang, Kai|Song, Haizhu|Wang, Rui|Chu, Xiaoyuan|Chen, Longbang
PMID: 27566568
Journal: Alcohol Clin Exp Res. 2016 Oct;40(10):2094-2101.
Title: Possible Mechanisms of Ethanol-Mediated Colorectal Carcinogenesis: The Role of Cytochrome P4502E1, Etheno-DNA Adducts, and the Anti-Apoptotic Protein Mcl-1.
Author: Koehler, Bruno Christian|Arslic-Schmitt, Tatjana|Peccerella, Theresa|Scherr, Anna-Lena|Schulze-Bergkamen, Henning|Bruckner, Thomas|Gdynia, Georg|Jager, Dirk|Mueller, Sebastian|Bartsch, Helmut|Seitz, Helmut K
PMID: 27581253
Journal: Sci Rep. 2016 Nov 14;6:36855.
Title: Didox and resveratrol sensitize colorectal cancer cells to doxorubicin via activating apoptosis and ameliorating P-glycoprotein activity.
Author: Khaleel, Sahar A|Al-Abd, Ahmed M|Ali, Azza A|Abdel-Naim, Ashraf B
PMID: 27841296
Journal: Oncotarget. 2016 Dec 27;7(52):87136-87146.
Title: RhoA regulates resistance to irinotecan by regulating membrane transporter and apoptosis signaling in colorectal cancer.
Author: Ruihua, Huang|Mengyi, Zhang|Chong, Zhao|Meng, Qiu|Xin, Ma|Qiulin, Tang|Feng, Bi|Ming, Liu
PMID: 27888624
Journal: Mol Cancer Ther. 2016 Dec;15(12):3055-3063.
Title: STAT1 Promotes KRAS Colon Tumor Growth and Susceptibility to Pharmacological Inhibition of Translation Initiation Factor eIF4A.
Author: Wang, Shuo|Darini, Cedric|Desaubry, Laurent|Koromilas, Antonis E
PMID: 27913706
Journal: Oncogene. 2017 Feb 2;36(5):700-713.
Title: MUC13 protects colorectal cancer cells from death by activating the NF-kappaB pathway and is a potential therapeutic target.
Author: Sheng, Y H|He, Y|Hasnain, S Z|Wang, R|Tong, H|Clarke, D T|Lourie, R|Oancea, I|Wong, K Y|Lumley, J W|Florin, T H|Sutton, P|Hooper, J D|McMillan, N A|McGuckin, M A
PMID: 27399336
Journal: Oncotarget. 2017 Jan 31;8(5):7502-7520.
Title: BTG1 might be employed as a biomarker for carcinogenesis and a target for gene therapy in colorectal cancers.
Author: Zhao, Shuang|Chen, Shu-Rui|Yang, Xue-Feng|Shen, Dao-Fu|Takano, Yasuo|Su, Rong-Jian|Zheng, Hua-Chuan
PMID: 27447746
Journal: Int J Oncol. 2017 Jan;50(1):329-336.
Title: CD44-shRNA recombinant adenovirus inhibits cell proliferation, invasion, and migration, and promotes apoptosis in HCT116 colon cancer cells.
Author: Lee, Soo Young|Kim, Kyung Ae|Kim, Chang Hyun|Kim, Young Jin|Lee, Jae-Hyuk|Kim, Hyeong Rok
PMID: 27959393
Journal: Oncotarget. 2017 Feb 7;8(6):9280-9292.
Title: Co-targeting translation and proteasome rapidly kills colon cancer cells with mutant RAS/RAF via ER stress.
Author: Li, Xiangyun|Li, Mei|Ruan, Hang|Qiu, Wei|Xu, Xiang|Zhang, Lin|Yu, Jian
PMID: 28030835
Journal: BMC Cancer. 2017 Jan 3;17(1):4.
Title: Novel derivative of aminobenzenesulfonamide (3c) induces apoptosis in colorectal cancer cells through ROS generation and inhibits cell migration.
Author: Al-Khayal, Khayal|Alafeefy, Ahmed|Vaali-Mohammed, Mansoor-Ali|Mahmood, Amer|Zubaidi, Ahmed|Al-Obeed, Omar|Khan, Zahid|Abdulla, Maha|Ahmad, Rehan
PMID: 28049506
Journal: Mol Cancer Res. 2017 Jun;15(6):708-713.
Title: Chromosome 20q Amplification Defines a Subtype of Microsatellite Stable, Left-Sided Colon Cancers with Wild-type RAS/RAF and Better Overall Survival.
Author: Ptashkin, Ryan N|Pagan, Carlos|Yaeger, Rona|Middha, Sumit|Shia, Jinru|O'Rourke, Kevin P|Berger, Michael F|Wang, Lu|Cimera, Robert|Wang, Jiajing|Klimstra, David S|Saltz, Leonard|Ladanyi, Marc|Zehir, Ahmet|Hechtman, Jaclyn F
PMID: 28184012
Journal: Evid Based Complement Alternat Med. 2017;2017:5180707.
Title: Helicteric Acid, Oleanic Acid, and Betulinic Acid, Three Triterpenes from Helicteres angustifolia L., Inhibit Proliferation and Induce Apoptosis in HT-29 Colorectal Cancer Cells via Suppressing NF-kappaB and STAT3 Signaling.
Author: Su, Dan|Gao, Yu-Qiao|Dai, Wei-Bo|Hu, Ying|Wu, Yan-Fen|Mei, Quan-Xi
PMID: 28331523
Journal: Transl Oncol. 2017 Jun;10(3):332-339.
Title: Irinotecan Upregulates Fibroblast Growth Factor Receptor 3 Expression in Colorectal Cancer Cells, Which Mitigates Irinotecan-Induced Apoptosis.
Author: Erdem, Zeynep N|Schwarz, Stefanie|Drev, Daniel|Heinzle, Christine|Reti, Andrea|Heffeter, Petra|Hudec, Xenia|Holzmann, Klaus|Grasl-Kraupp, Bettina|Berger, Walter|Grusch, Michael|Marian, Brigitte
PMID: 28340475
Journal: Acta Pharmacol Sin. 2017 Jun;38(6):885-896.
Title: Codelivery of dihydroartemisinin and doxorubicin in mannosylated liposomes for drug-resistant colon cancer therapy.
Author: Kang, Xue-Jia|Wang, Hui-Yuan|Peng, Hui-Ge|Chen, Bin-Fan|Zhang, Wen-Yuan|Wu, Ai-Hua|Xu, Qin|Huang, Yong-Zhuo
PMID: 28479604
Journal: J Med Food. 2017 May;20(5):485-490.
Title: Mammea longifolia Planch. and Triana Fruit Extract Induces Cell Death in the Human Colon Cancer Cell Line, SW480, via Mitochondria-Related Apoptosis and Activation of p53.
Author: Li, Chunmei|Jeong, Yoonhwa|Kim, Misook
PMID: 28504908
Journal: Intest Res. 2017 Apr;15(2):174-181.
Title: Parthenolide promotes apoptotic cell death and inhibits the migration and invasion of SW620 cells.
Author: Liu, Yu Chuan|Kim, Se Lim|Park, Young Ran|Lee, Soo-Teik|Kim, Sang Wook
PMID: 28522946
Journal: Mol Cancer Ther. 2017 Oct;16(10):2178-2190.
Title: A Novel Combination Treatment Targeting BCL-XL and MCL1 for KRAS/BRAF-mutated and BCL2L1-amplified Colorectal Cancers.
Author: Cho, Sung-Yup|Han, Jee Yun|Na, Deukchae|Kang, Wonyoung|Lee, Ahra|Kim, Jooyoung|Lee, Jieun|Min, Seoyeon|Kang, Jinjoo|Chae, Jeesoo|Kim, Jong-Il|Park, Hansoo|Lee, Won-Suk|Lee, Charles
PMID: 28611106
Journal: Clin Cancer Res. 2017 Sep 15;23(18):5573-5584.
Title: ATF3 Repression of BCL-XL Determines Apoptotic Sensitivity to HDAC Inhibitors across Tumor Types.
Author: Chueh, Anderly C|Tse, Janson W T|Dickinson, Michael|Ioannidis, Paul|Jenkins, Laura|Togel, Lars|Tan, BeeShin|Luk, Ian|Davalos-Salas, Mercedes|Nightingale, Rebecca|Thompson, Matthew R|Williams, Bryan R G|Lessene, Guillaume|Lee, Erinna F|Fairlie, Walter D|Dh
PMID: 28611196
Journal: Expert Rev Anticancer Ther. 2017 Sep;17(9):857-863.
Title: Down-regulation of liver-intestine cadherin enhances noscapine-induced apoptosis in human colon cancer cells.
Author: Tian, Xia|Liu, Meng|Zhu, Qingxi|Tan, Jie|Liu, Weijie|Wang, Yanfen|Chen, Wei|Zou, Yanli|Cai, Yishan|Han, Zheng|Huang, Xiaodong
PMID: 28622054
Journal: Sci Technol Adv Mater. 2017 May 31;18(1):364-373.
Title: Evaluation of in vitro cytotoxicity, biocompatibility, and changes in the expression of apoptosis regulatory proteins induced by cerium oxide nanocrystals.
Author: Khan, Shahanavaj|Ansari, Anees A|Rolfo, Christian|Coelho, Andreia|Abdulla, Maha|Al-Khayal, Khayal|Ahmad, Rehan
PMID: 28634498
Journal: Theranostics. 2017 Jun 11;7(8):2339-2349.
Title: YD277 Suppresses Triple-Negative Breast Cancer Partially Through Activating the Endoplasmic Reticulum Stress Pathway.
Author: Chen, Zekun|Wu, Qiuju|Ding, Ye|Zhou, Wenhui|Liu, Rong|Chen, Haiying|Zhou, Jia|Feng, Jing|Chen, Ceshi
PMID: 28740556
Journal: Biomed Pharmacother. 2017 Oct;94:767-773.
Title: MTDH and MAP3K1 are direct targets of apoptosis-regulating miRNAs in colorectal carcinoma.
Author: Salem, Sohair M|Hamed, Ahmed R|Mosaad, Rehab M
PMID: 28802228
Journal: Biomark Med. 2017 Dec;11(12):1103-1111.
Title: The ratio of thioredoxin/Keap1 protein level is a predictor of distant metastasis in colorectal cancer.
Author: Chang, Liang-Che|Fan, Chung-Wei|Tseng, Wen-Ko|Chein, Hui-Ping|Hsieh, Tsan-Yu|Chen, Jim-Ray|Hwang, Cheng-Cheng|Hua, Chung-Ching
PMID: 29053012
Journal: Biomed Pharmacother. 2017 Dec;96:834-846.
Title: Antiproliferative and apoptosis inducing effects of citral via p53 and ROS-induced mitochondrial-mediated apoptosis in human colorectal HCT116 and HT29 cell lines.
Author: Sheikh, Bassem Y|Sarker, Md Moklesur Rahman|Kamarudin, Muhamad Noor Alfarizal|Mohan, Gokula
PMID: 29078261
Journal: Sci Rep. 2017 Nov 6;7(1):14571.
Title: Involvement of autophagy in the outcome of mitotic catastrophe.
Author: Sorokina, Irina V|Denisenko, Tatiana V|Imreh, Gabriela|Tyurin-Kuzmin, Pyotr A|Kaminskyy, Vitaliy O|Gogvadze, Vladimir|Zhivotovsky, Boris
PMID: 29109414
Journal: Apoptosis. 2017 Dec;22(12):1553-1563.
Title: Bromoethylindole (BEI-9) redirects NF-kappaB signaling induced by camptothecin and TNFalpha to promote cell death in colon cancer cells.
Author: Chowdhury, Rupak|Gales, Dominique|Valenzuela, Paloma|Miller, Sonni|Yehualaeshet, Teshome|Manne, Upender|Francia, Giulio|Samuel, Temesgen
PMID: 29116428
Journal: Oncotarget. 2017 Aug 2;8(59):99451-99469.
Title: Curcumin interacts with sildenafil to kill GI tumor cells via endoplasmic reticulum stress and reactive oxygen/ nitrogen species.
Author: Roberts, Jane L|Poklepovic, Andrew|Booth, Laurence
PMID: 29245915
Journal: J Biol Regul Homeost Agents. 2017 Oct-Dec;31(4):923-927.
Title: Autophagy-related gene expression in colorectal cancer patients.
Author: Bednarczyk, M|Muc-Wierzgon, M|Waniczek, D|Fatyga, E|Klakla, K|Mazurek, U|Wierzgon, J
PMID: 29254294
Journal: Oncotarget. 2017 Nov 17;8(65):109094-109106.
Title: Shikonin induces ROS-based mitochondria-mediated apoptosis in colon cancer.
Author: Liang, Wenquan|Cui, Jianxin|Zhang, Kecheng|Xi, Hongqing|Cai, Aizhen|Li, Jiyang|Gao, Yunhe|Hu, Chong|Liu, Yi|Lu, Yixun|Wang, Ning|Wu, Xiaosong|Wei, Bo|Chen, Lin
PMID: 29312593
Journal: Gen Physiol Biophys. 2017 Dec;36(5):539-547.
Title: Cyclin-dependent kinase 2 inhibitor SU9516 increases sensitivity of colorectal carcinoma cells Caco-2 but not HT29 to BH3 mimetic ABT-737.
Author: Stefanikova, Andrea|Klacanova, Katarina|Pilchova, Ivana|Hatok, Jozef|Racay, Peter
PMID: 29372687
Journal: Cancer Growth Metastasis. 2017 Sep 18;10:1179064417730559.
Title: Upregulated Heat Shock Proteins After Hyperthermic Chemotherapy Point to Induced Cell Survival Mechanisms in Affected Tumor Cells From Peritoneal Carcinomatosis.
Author: Grimmig, Tanja|Moll, Eva-Maria|Kloos, Kerstin|Thumm, Rebecca|Moench, Romana|Callies, Simone|Kreckel, Jennifer|Vetterlein, Malte|Pelz, Joerg|Polat, Buelent|Tripathi, Sudipta|Rehder, Roberta|Ribas, Carmen M|Chandraker, Anil|Germer, Christoph-T|Waaga-Gasser,
PMID: 29403306
Journal: Integr Cancer Ther. 2018 Jun;17(2):271-281.
Title: Scorpion Venom Causes Upregulation of p53 and Downregulation of Bcl-xL and BID Protein Expression by Modulating Signaling Proteins Erk(1/2) and STAT3, and DNA Damage in Breast and Colorectal Cancer Cell Lines.
Author: Al-Asmari, Abdulrahman Khazim|Riyasdeen, Anvarbatcha|Islam, Mozaffarul
PMID: 28438053
Journal: Mol Carcinog. 2018 Mar;57(3):347-360.
Title: Antitumor activity of Lepidium latifolium and identification of the epithionitrile 1-cyano-2,3-epithiopropane as its major active component.
Author: Conde-Rioll, Maria|Gajate, Consuelo|Fernandez, Jose J|Villa-Pulgarin, Janny A|Napolitano, Jose G|Norte, Manuel|Mollinedo, Faustino
PMID: 29073716
Journal: Cancer Res Treat. 2018 Jul;50(3):992-1008.
Title: Long Noncoding RNA HEIH Promotes Colorectal Cancer Tumorigenesis via Counteracting miR-939Mediated Transcriptional Repression of Bcl-xL.
Author: Cui, Chunhui|Zhai, Duanyang|Cai, Lianxu|Duan, Qiaobin|Xie, Lang|Yu, Jinlong
PMID: 29081216
Journal: Clin Transl Oncol. 2018 Jun;20(6):775-784.
Title: LOC285629 regulates cell proliferation and motility in colorectal cancer cells.
Author: Nasir, S N|Abu, N|Ab Mutalib, N S|Ishak, M|Sagap, I|Mazlan, L|Rose, I M|Jamal, R
PMID: 29098557
Journal: Biomed Pharmacother. 2018 Feb;98:180-190.
Title: Protective effect of Coptisine from Rhizoma Coptidis on LPS/D-GalN-induced acute liver failure in mice through up-regulating expression of miR-122.
Author: Chai, Fang-Ni|Zhang, Jiang|Xiang, Hong-Mei|Xu, He-Shan|Li, Yuan-Feng|Ma, Wen-Yu|Li, Xue-Gang|Ye, Xiao-Li
PMID: 29253766
Journal: Cancer Sci. 2018 Mar;109(3):656-665.
Title: Cdc37 facilitates cell survival of colorectal carcinoma via activating the CDK4 signaling pathway.
Author: Zhu, Jianjun|Yan, Fang|Tao, Jia|Zhu, Xiaohua|Liu, Jiayou|Deng, Shishan|Zhang, Xiaoming
PMID: 29288563
Journal: Mol Med Rep. 2018 Apr;17(4):5143-5149.
Title: Silencing Lin28 promotes apoptosis in colorectal cancer cells by upregulating let7c targeting of antiapoptotic BCL2L1.
Author: Zhang, Haogang|Zong, Yaguang|Qiu, Gongcai|Jia, Ruichun|Xu, Xunzheng|Wang, Fujing|Wu, Dequan
PMID: 29393430
Journal: Cancer Biol Ther. 2018 Jun 3;19(6):465-474.
Title: DZNep represses Bcl-2 expression and modulates apoptosis sensitivity in response to Nutlin-3a.
Author: Zhou, Yalu|Perez, Ricardo E|Duan, Lei|Maki, Carl G
PMID: 29394130
Journal: Phytother Res. 2018 Apr;32(4):657-666.
Title: Antiproliferative activity and apoptosis induction by trijuganone C isolated from the root of Salvia miltiorrhiza Bunge (Danshen).
Author: Uto, Takuhiro|Tung, Nguyen Huu|Ohta, Tomoe|Juengsanguanpornsuk, Wipawee|Hung, Le Quoc|Hai, Nguyen Thanh|Long, Dinh Doan|Thuong, Phuong Thien|Okubo, Shinya|Hirata, Sakiko|Shoyama, Yukihiro
PMID: 29464799
Journal: Pharmacogn Mag. 2018 Jan;13(Suppl 4):S801-S806.
Title: Viwithan, a Standardized Withania somnifera Root Extract Induces Apoptosis in Murine Melanoma Cells.
Author: Sudeep, H V|Gouthamchandra, K|Venkatesh, B J|Prasad, K Shyam
PMID: 29491636
Journal: Int J Oncol. 2018 Mar 7.
Title: Apigenin induces apoptosis by suppressing Bcl-xl and Mcl-1 simultaneously via signal transducer and activator of transcription 3 signaling in colon cancer.
Author: Maeda, Yuzo|Takahashi, Hiroki|Nakai, Nozomu|Yanagita, Takeshi|Ando, Nanako|Okubo, Tomotaka|Saito, Kenta|Shiga, Kazuyoshi|Hirokawa, Takahisa|Hara, Masayasu|Ishiguro, Hideyuki|Matsuo, Yoichi|Takiguchi, Shuji
PMID: 29512707
Journal: Mol Cancer Ther. 2018 May;17(5):977-987.
Title: A miR-29b Byproduct Sequence Exhibits Potent Tumor-Suppressive Activities via Inhibition of NF-kappaB Signaling in KRAS-Mutant Colon Cancer Cells.
Author: Inoue, Akira|Mizushima, Tsunekazu|Wu, Xin|Okuzaki, Daisuke|Kambara, Nanami|Ishikawa, Sho|Wang, Jiaqi|Qian, Yamin|Hirose, Haruka|Yokoyama, Yuhki|Ikeshima, Ryo|Hiraki, Masayuki|Miyoshi, Norikatsu|Takahashi, Hidekazu|Haraguchi, Naotsugu|Hata, Taishi|Matsuda,
PMID: 29545333
Journal: Molecules. 2018 Mar 22;23(4). pii: molecules23040723.
Title: Food Additive Sodium Benzoate (NaB) Activates NFkappaB and Induces Apoptosis in HCT116 Cells.
Author: Yilmaz, Betul|Karabay, Arzu Zeynep
PMID: 29565269
Journal: Oncotarget. 2018 Feb 13;9(17):13834-13847.
Title: Bcl-xL as a poor prognostic biomarker and predictor of response to adjuvant chemotherapy specifically in BRAF-mutant stage II and III colon cancer.
Author: Dunne, Philip D|Coleman, Helen G|Bankhead, Peter|Alderdice, Matthew|Gray, Ronan T|McQuaid, Stephen|Bingham, Victoria|Loughrey, Maurice B|James, Jacqueline A|McCorry, Amy M B|Gilmore, Alan|Holohan, Caitriona|Klingbiel, Dirk|Tejpar, Sabine|Johnston, Patrick
PMID: 29568398
Journal: Oncol Lett. 2018 Jun;15(6):8695-8702.
Title: Upregulation of let-7f-5p promotes chemotherapeutic resistance in colorectal cancer by directly repressing several pro-apoptotic proteins.
Author: Tie, Yateng|Chen, Chong|Yang, Yanli|Qian, Zhen|Yuan, Hang|Wang, Huan|Tang, Haili|Peng, Yao|Du, Xilin|Liu, Bin
PMID: 29805607
Journal: Oncol Lett. 2018 May;15(5):7344-7354.
Title: Expression profile of NF-kappaB regulated genes in sporadic colorectal cancer patients.
Author: Gonzalez-Quezada, Betsy Annel|Santana-Bejarano, Uriel Francisco|Corona-Rivera, Alfredo|Pimentel-Gutierrez, Helia Judith|Silva-Cruz, Rocio|Ortega-De-la-Torre, Citlalli|Franco-Topete, Ramon|Franco-Topete, Karina|Centeno-Flores, Manuel Willebaldo|Maciel-Guti
PMID: 29849793
Journal: Nan Fang Yi Ke Da Xue Xue Bao. 2018 May 20;38(5):511-519.
Title: [Role of allograft inflammatory factor-1 in regulating the proliferation, migration and apoptosis of colorectal cancer cells].
Author: Ai, Xiao-Lan|Yao, Fang|Wang, Xiao-Jing|Duan, Dong-Bei|Li, Ke|Hu, Zi-You|Yin, Guo|Wang, Mei|Wu, Bing-Yi
PMID: 29891445
Journal: Onco Targets Ther. 2018 Jun 5;11:3313-3322.
Title: Novel quinazoline-based sulfonamide derivative (3D) induces apoptosis in colorectal cancer by inhibiting JAK2-STAT3 pathway.
Author: Al-Obeed, Omar|Vaali-Mohammed, Mansoor-Ali|Eldehna, Wagdy M|Al-Khayal, Khayal|Mahmood, Amer|Abdel-Aziz, Hatem A|Zubaidi, Ahmed|Alafeefy, Ahmed|Abdulla, Maha|Ahmad, Rehan
PMID: 29892198
Journal: Mol Carcinog. 2018 Oct;57(10):1383-1395.
Title: A452, an HDAC6-selective inhibitor, synergistically enhances the anticancer activity of chemotherapeutic agents in colorectal cancer cells.
Author: Won, Hye-Rim|Ryu, Hyun-Wook|Shin, Dong-Hee|Yeon, Soo-Keun|Lee, Dong Hoon|Kwon, So Hee
PMID: 29917295
Journal: Cell Physiol Biochem. 2018;47(4):1432-1441.
Title: Knockdown of MiR-20a Enhances Sensitivity of Colorectal Cancer Cells to Cisplatin by Increasing ASK1 Expression.
Author: Zhang, Luyao|He, Liang|Zhang, Hua|Chen, Yan
PMID: 29940575
Journal: Mol Cancer. 2018 Aug 1;17(1):111.
Title: MASTL induces Colon Cancer progression and Chemoresistance by promoting Wnt/beta-catenin signaling.
Author: Uppada, Srijayaprakash Babu|Gowrikumar, Saiprasad|Ahmad, Rizwan|Kumar, Balawant|Szeglin, Bryan|Chen, Xi|Smith, J Joshua|Batra, Surinder K|Singh, Amar B|Dhawan, Punita
PMID: 30068336
Journal: Cancer Lett. 2018 Oct 28;435:23-31.
Title: Hypertonicity-imposed BCL-XL addiction primes colorectal cancer cells for death.
Author: Heimer, Sina|Knoll, Gertrud|Steixner, Charlotte|Calance, Diana Nicoleta|Trinh, Dieu Thuy|Ehrenschwender, Martin
PMID: 30075205
Journal: Mol Biol Rep. 2018 Oct;45(5):1339-1348.
Title: A natural flavonoid lawsonaringenin induces cell cycle arrest and apoptosis in HT-29 colorectal cancer cells by targeting multiple signalling pathways.
Author: Anwar, Areeba|Uddin, Nizam|Siddiqui, Bina Shaheen|Siddiqui, Rafat Ali|Begum, Sabira|Choudhary, Muhammad Iqbal
PMID: 30088202
Journal: Int J Biochem Cell Biol. 2018 Oct;103:89-98.
Title: Lysosomal permeabilization and endoplasmic reticulum stress mediate the apoptotic response induced after photoactivation of a lipophilic zinc(II) phthalocyanine.
Author: Chiarante, Nicolas|Garcia Vior, Maria C|Rey, Osvaldo|Marino, Julieta|Roguin, Leonor P
PMID: 30130653
Journal: EMBO Mol Med. 2018 Aug 24. pii: emmm.201708699.
Title: Cancer cell adaptation to hypoxia involves a HIF-GPRC5A-YAP axis.
Author: Greenhough, Alexander|Bagley, Clare|Heesom, Kate J|Gurevich, David B|Gay, David|Bond, Mark|Collard, Tracey J|Paraskeva, Chris|Martin, Paul|Sansom, Owen J|Malik, Karim|Williams, Ann C
PMID: 30143543
Journal: Oncol Rep. 2018 Oct 22.
Title: Galla Rhois water extract inhibits lung metastasis by inducing AMPKmediated apoptosis and suppressing metastatic properties of colorectal cancer cells.
Author: Mun, Jeong-Geon|Kee, Ji-Ye|Han, Yo-Han|Lee, Sullim|Park, Seong-Hwan|Jeon, Hee Dong|Hong, Seung-Heon
PMID: 30365120
Journal: J Gastroenterol Hepatol. 2018 Oct 30.
Title: Tauroursodeoxycholic acid attenuates colitis-associated colon cancer by inhibiting nuclear factor kappaB signaling.
Author: Kim, Young Hoon|Kim, Jee Hyun|Kim, Byeong Gwan|Lee, Kook Lae|Kim, Ji Won|Koh, Seong-Joon
PMID: 30378164