Primary Site >> Pancreatic Cancer

Gene >> BCL2

Journal: Mod Pathol. 1997 Apr;10(4):372-9.
Title: Hepatobiliary and pancreatic mucinous cystadenocarcinomas with mesenchymal stroma: analysis of estrogen receptors/progesterone receptors and expression of tumor-associated antigens.
Author: Weihing, R R|Shintaku, I P|Geller, S A|Petrovic, L M
PMID: 9110301
Journal: Anticancer Res. 1998 Jan-Feb;18(1B):615-8.
Title: Clinical contribution of bcl-2, p53 and Ki-67 proteins in pancreatic ductal adenocarcinoma.
Author: Makinen, K|Hakala, T|Lipponen, P|Alhava, E|Eskelinen, M
PMID: 9568186
Journal: Langenbecks Arch Surg. 1998 Apr;383(2):152-5.
Title: Prognostic significance of molecular alterations in human pancreatic carcinoma--an immunohistological study.
Author: Gansauge, F|Gansauge, S|Schmidt, E|Muller, J|Beger, H G
PMID: 9641888
Journal: Scand J Gastroenterol. 1998 May;33(5):535-9.
Title: An immunohistochemical study of bcl-2 and p53 protein expression in pancreatic carcinomas.
Author: Ohshio, G|Suwa, H|Imamura, T|Yamaki, K|Tanaka, T|Hashimoto, Y|Imamura, M
PMID: 9648995
Journal: Anticancer Res. 1998 Jul-Aug;18(4A):2559-66.
Title: An exogenous cdk inhibitor, butyrolactone-I, induces apoptosis with increased Bax/Bcl-2 ratio in p53-mutated pancreatic cancer cells.
Author: Wada, M|Hosotani, R|Lee, J U|Doi, R|Koshiba, T|Fujimoto, K|Miyamoto, Y|Tsuji, S|Nakajima, S|Okuyama, A|Imamura, M
PMID: 9703910
Journal: Histopathology. 1998 Nov;33(5):432-9.
Title: Apoptotic index and apoptosis influencing proteins bcl-2, mcl-1, bax and caspases 3, 6 and 8 in pancreatic carcinoma.
Author: Virkajarvi, N|Paakko, P|Soini, Y
PMID: 9839167
Journal: Gut. 1998 Sep;43(3):414-21.
Title: bax, but not bcl-2, influences the prognosis of human pancreatic cancer.
Author: Friess, H|Lu, Z|Graber, H U|Zimmermann, A|Adler, G|Korc, M|Schmid, R M|Buchler, M W
PMID: 9863489
Journal: Langenbecks Arch Chir Suppl Kongressbd. 1998;115(Suppl I):69-72.
Title: [Prognostic value of molecular biologogy and immunologic parameters in human pancreatic carcinoma].
Author: Gansauge, F|Gansauge, S|Muller, J|Schmid, E|Beger, H G
PMID: 14518215
Journal: Oncology. 1999;56(1):73-82.
Title: Immunohistochemical analysis of Bcl-2, Bax, Bcl-X, and Mcl-1 expression in pancreatic cancers.
Author: Miyamoto, Y|Hosotani, R|Wada, M|Lee, J U|Koshiba, T|Fujimoto, K|Tsuji, S|Nakajima, S|Doi, R|Kato, M|Shimada, Y|Imamura, M
PMID: 9885381
Journal: Ann Surg Oncol. 1999 Apr-May;6(3):279-85.
Title: Gemcitabine-induced programmed cell death (apoptosis) of human pancreatic carcinoma is determined by Bcl-2 content.
Author: Bold, R J|Chandra, J|McConkey, D J
PMID: 10340887
Journal: Int J Mol Med. 1999 Jun;3(6):647-53.
Title: Induction of growth inhibition and apoptosis in pancreatic cancer cells by auristatin-PE and gemcitabine.
Author: Li, Y|Singh, B|Ali, N|Sarkar, F H
PMID: 10341297
Journal: Br J Cancer. 1999 Jun;80(7):1075-9.
Title: Bcl-2 expression related to altered p53 protein and its impact on the progression of human pancreatic carcinoma.
Author: Hu, Y X|Watanabe, H|Ohtsubo, K|Yamaguchi, Y|Ha, A|Motoo, Y|Okai, T|Sawabu, N
PMID: 10362119
Journal: Eur J Surg. 1999 Apr;165(4):292-306.
Title: Prognosis of human pancreatic adenocarcinoma: review of clinical and histopathological variables and possible uses of new molecular methods.
Author: Eskelinen, M J|Haglund, U H
PMID: 10365829
Journal: Pathol Oncol Res. 1999;5(2):146-51.
Title: Epidermal growth factor receptor, somatostatin and bcl-2 in human pancreatic tumor xenografts. An immunohistochemical study.
Author: Zalatnai, A
PMID: 10393368
Journal: J Gastrointest Surg. 1999 Jan-Feb;3(1):74-80; discussion 81.
Title: Bak expression and cell death occur in peritumorous tissue but not in pancreatic cancer cells.
Author: Graber, H U|Friess, H|Zimmermann, A|Korc, M|Adler, G|Schmid, R|Buchler, M W
PMID: 10457328
Journal: Int J Mol Med. 1999 Nov;4(5):501-7.
Title: Molecular effects of taxol and caffeine on pancreatic cancer cells.
Author: Gururajanna, B|Al-Katib, A A|Li, Y W|Aranha, O|Vaitkevicius, V K|Sarkar, F H
PMID: 10534572
Journal: Eur J Cancer. 1999 Sep;35(9):1374-80.
Title: Role of Bcl-2 family proteins (Bax, Bcl-2 and Bcl-X) on cellular susceptibility to radiation in pancreatic cancer cells.
Author: Lee, J U|Hosotani, R|Wada, M|Doi, R|Kosiba, T|Fujimoto, K|Miyamoto, Y|Tsuji, S|Nakajima, S|Nishimura, Y|Imamura, M
PMID: 10658530
Journal: Int J Pancreatol. 1999 Dec;26(3):163-71.
Title: An immunohistochemical study of the expression of bcl-2 and p53 oncoproteins in pancreatic intraepithelial neoplasia and pancreatic cancer.
Author: Tomaszewska, R|Karcz, D|Stachura, J
PMID: 10732293
Journal: Cancer Gene Ther. 2000 Mar;7(3):373-83.
Title: Adenovirus-mediated anti-K-ras ribozyme induces apoptosis and growth suppression of human pancreatic carcinoma.
Author: Tsuchida, T|Kijima, H|Hori, S|Oshika, Y|Tokunaga, T|Kawai, K|Yamazaki, H|Ueyama, Y|Scanlon, K J|Tamaoki, N|Nakamura, M
PMID: 10766343
Journal: Cancer Gene Ther. 2000 Apr;7(4):545-56.
Title: Modulation of drug cytotoxicity by reintroduction of wild-type p53 gene (Ad5CMV-p53) in human pancreatic cancer.
Author: Cascallo, M|Calbo, J|Gelpi, J L|Mazo, A
PMID: 10811472
Journal: Cancer. 2000 May 1;88(9):2000-9.
Title: Medroxyprogesterone acetate inhibits human pancreatic carcinoma cell growth by inducing apoptosis in association with Bcl-2 phosphorylation.
Author: Abe, M|Yamashita, J|Ogawa, M
PMID: 10813710
Journal: Int J Pancreatol. 2000 Apr;27(2):113-22.
Title: Immunohistochemical analysis of apoptosis-related proteins in human embryonic and fetal pancreatic tissues.
Author: Kobayash, H|Doi, R|Hosotani, R|Miyamoto, Y|Koshiba, T|Fujimoto, K|Ida, J|Tsuji, S|Nakajima, S|Kawaguchi, M|Shiota, K|Imamura, M
PMID: 10862510
Journal: J Cell Biochem. 2000 Sep 7;79(3):355-69.
Title: MEK/ERK signaling pathway regulates the expression of Bcl-2, Bcl-X(L), and Mcl-1 and promotes survival of human pancreatic cancer cells.
Author: Boucher, M J|Morisset, J|Vachon, P H|Reed, J C|Laine, J|Rivard, N
PMID: 10972974
Journal: Hepatogastroenterology. 2000 Jul-Aug;47(34):973-7.
Title: p53 protein expression in intraductal papillary mucinous tumors (IPMT) of the pancreas as an indicator of tumor malignancy.
Author: Kawahira, H|Kobayashi, S|Kaneko, K|Asano, T|Ochiai, T
PMID: 11020860
Journal: Breast Cancer. 2000;7(2):130-5.
Title: Medroxyprogesterone acetate and cancer cachexia: interleukin-6 involvement.
Author: Yamashita, J I|Ogawa, M
PMID: 11029784
Journal: Anticancer Res. 2000 Sep-Oct;20(5A):2915-22.
Title: Antineoplastic activity of a novel multimeric gemcitabine-monophosphate prodrug against thyroid cancer cells in vitro.
Author: Kotchetkov, R|Groschel, B|Gmeiner, W H|Krivtchik, A A|Trump, E|Bitoova, M|Cinatl, J|Kornhuber, B|Cinatl, J
PMID: 11062701
Journal: Oncogene. 2000 Nov 16;19(48):5477-86.
Title: Bcl-XL protects pancreatic adenocarcinoma cells against CD95- and TRAIL-receptor-mediated apoptosis.
Author: Hinz, S|Trauzold, A|Boenicke, L|Sandberg, C|Beckmann, S|Bayer, E|Walczak, H|Kalthoff, H|Ungefroren, H
PMID: 11114725
Journal: FEBS Lett. 2001 Feb 23;491(1-2):104-8.
Title: Inhibition of caspase-1 induces cell death in pancreatic carcinoma cells and potentially modulates expression levels of bcl-2 family proteins.
Author: Schlosser, S|Gansauge, F|Ramadani, M|Beger, H G|Gansauge, S
PMID: 11226429
Journal: Clin Cancer Res. 2001 Feb;7(2):407-14.
Title: Combination of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and actinomycin D induces apoptosis even in TRAIL-resistant human pancreatic cancer cells.
Author: Matsuzaki, H|Schmied, B M|Ulrich, A|Standop, J|Schneider, M B|Batra, S K|Picha, K S|Pour, P M
PMID: 11234897
Journal: Anticancer Res. 2001 Jan-Feb;21(1A):477-80.
Title: Apoptosis-induction and phosphorylation state in human pancreatic carcinoma xenografts following octreotide treatment.
Author: Zalatnai, A|Pogany, V
PMID: 11299782
Journal: Pancreas. 2001 Jul;23(1):72-9.
Title: Pancreatic adenocarcinoma cell lines show variable susceptibility to TRAIL-mediated cell death.
Author: Ibrahim, S M|Ringel, J|Schmidt, C|Ringel, B|Muller, P|Koczan, D|Thiesen, H J|Lohr, M
PMID: 11451151
Journal: Hepatogastroenterology. 2001 May-Jun;48(39):879-83.
Title: Immunohistochemical study of genetic alterations in intraductal and invasive ductal tumors of the pancreas.
Author: Islam, H K|Fujioka, Y|Tomidokoro, T|Sugiura, H|Takahashi, T|Kondo, S|Katoh, H
PMID: 11462947
Journal: Anticancer Res. 2001 May-Jun;21(3B):1919-24.
Title: Mechanism of growth-inhibitory effect of cisplatin on human pancreatic cancer cells and status of p53 gene.
Author: Seki, T|Ohba, N|Makino, R|Funatomi, H|Mitamura, K
PMID: 11497278
Journal: FEBS Lett. 2001 Aug 17;503(2-3):151-7.
Title: The anti-apoptotic protein BAG-3 is overexpressed in pancreatic cancer and induced by heat stress in pancreatic cancer cell lines.
Author: Liao, Q|Ozawa, F|Friess, H|Zimmermann, A|Takayama, S|Reed, J C|Kleeff, J|Buchler, M W
PMID: 11513873
Journal: J Surg Res. 2001 Sep;100(1):11-7.
Title: Chemosensitization of pancreatic cancer by inhibition of the 26S proteasome.
Author: Bold, R J|Virudachalam, S|McConkey, D J
PMID: 11516199
Journal: J Pathol. 2001 Aug;194(4):444-50.
Title: Bcl-2 expression in pancreas development and pancreatic cancer progression.
Author: Campani, D|Esposito, I|Boggi, U|Cecchetti, D|Menicagli, M|De Negri, F|Colizzi, L|Del Chiaro, M|Mosca, F|Fornaciari, G|Bevilacqua, G
PMID: 11523052
Journal: Proc Natl Acad Sci U S A. 2001 Aug 28;98(18):10332-7.
Title: A combinatorial approach for selectively inducing programmed cell death in human pancreatic cancer cells.
Author: Su , Z|Lebedeva, I V|Gopalkrishnan, R V|Goldstein, N I|Stein, C A|Reed, J C|Dent, P|Fisher, P B
PMID: 11526239
Journal: Cancer. 2001 Sep 1;92(5):1122-9.
Title: BCL2 expression correlates with metastatic potential in pancreatic cancer cell lines.
Author: Bold, R J|Virudachalam, S|McConkey, D J
PMID: 11571724
Journal: Anticancer Res. 2001 Jul-Aug;21(4A):2449-56.
Title: Interleukin-6 inhibits radiation induced apoptosis in pancreatic cancer cells.
Author: Miyamoto, Y|Hosotani, R|Doi, R|Wada, M|Ida, J|Tsuji, S|Kawaguchi, M|Nakajima, S|Kobayashi, H|Masui, T|Imamura, M
PMID: 11724306
Journal: J Biol Chem. 2002 Jan 18;277(3):2234-46. Epub 2001 Nov 1.
Title: Restoration of transforming growth factor-beta signaling enhances radiosensitivity by altering the Bcl-2/Bax ratio in the p53 mutant pancreatic cancer cell line MIA PaCa-2.
Author: Ahmed, Mansoor M|Alcock, Rachael A|Chendil, Damodaran|Dey, Swatee|Das, Anindita|Venkatasubbarao, Kolaparthi|Mohiuddin, Mohammed|Sun, LuZhe|Strodel, William E|Freeman, James W
PMID: 11694525
Journal: Am J Surg Pathol. 2002 Feb;26(2):216-24.
Title: Primary follicular lymphoma of the gastrointestinal tract: a clinical and pathologic study of 26 cases.
Author: Shia, Jinru|Teruya-Feldstein, Julie|Pan, Dorothy|Hegde, Abhijith|Klimstra, David S|Chaganti, R S K|Qin, Jing|Portlock, Carol S|Filippa, Daniel A
PMID: 11812943
Journal: Br J Cancer. 2002 Mar 18;86(6):886-92.
Title: Expression of survivin, a novel inhibitor of apoptosis and cell cycle regulatory protein, in pancreatic adenocarcinoma.
Author: Sarela, A I|Verbeke, C S|Ramsdale, J|Davies, C L|Markham, A F|Guillou, P J
PMID: 11953819
Journal: J Hepatobiliary Pancreat Surg. 2002;9(1):1-11.
Title: Molecular prognostic markers in pancreatic cancer.
Author: Ghaneh, Paula|Kawesha, Anthony|Evans, James D|Neoptolemos, John P
PMID: 12021893
Journal: Tumour Biol. 2002 Mar-Apr;23(2):76-86.
Title: E2F-1 gene therapy induces apoptosis and increases chemosensitivity in human pancreatic carcinoma cells.
Author: Elliott, Mary Jane|Farmer, Michael R|Atienza, Cesar Jr|Stilwell, Ariel|Dong, Yan Bin|Yang, Hai Liang|Wong, Sandra L|McMasters, Kelly M
PMID: 12065845
Journal: Cancer Chemother Pharmacol. 2002 Jun;49(6):504-10.
Title: Overexpression of Bax sensitizes human pancreatic cancer cells to apoptosis induced by chemotherapeutic agents.
Author: Xu, Zhong-Wei|Friess, Helmut|Buchler, Markus W|Solioz, Marc
PMID: 12107556
Journal: Oncology. 2002;62(4):354-62.
Title: Acquired resistance of pancreatic cancer cells towards 5-Fluorouracil and gemcitabine is associated with altered expression of apoptosis-regulating genes.
Author: Shi, Xin|Liu, Shengli|Kleeff, Jorg|Friess, Helmut|Buchler, Markus W
PMID: 12138244
Journal: Histopathology. 2002 Aug;41(2):122-6.
Title: Mixed ductal-pancreatic polypeptide-cell carcinoma of the pancreas.
Author: Chatelain, D|Parc, Y|Christin-Maitre, S|Parc, R|Flejou, J-F
PMID: 12147089
Journal: Br J Cancer. 2002 Aug 27;87(5):555-61.
Title: Retinoids cause apoptosis in pancreatic cancer cells via activation of RAR-gamma and altered expression of Bcl-2/Bax.
Author: Pettersson, F|Dalgleish, A G|Bissonnette, R P|Colston, K W
PMID: 12189556
Journal: Mol Cancer Ther. 2002 Sep;1(11):929-35.
Title: Lipoxygenase inhibitors attenuate growth of human pancreatic cancer xenografts and induce apoptosis through the mitochondrial pathway.
Author: Tong, Wei-Gang|Ding, Xian-Zhong|Witt, Richard C|Adrian, Thomas E
PMID: 12481414
Journal: Int J Gastrointest Cancer. 2002;32(2-3):73-81.
Title: Histopathological study of intraductal papillary mucinous tumor of the pancreas: special reference to the roles of Survivin and p53 in tumorigenesis of IPMT.
Author: Jinfeng, Ma|Kimura, Wataru|Sakurai, Fumiaki|Moriya, Toshiyuki|Takeshita, Akiko|Hirai, Ichiro
PMID: 12794243
Journal: Hepatobiliary Pancreat Dis Int. 2002 May;1(2):306-8.
Title: Expression of the bcl-2 gene and its significance in human pancreatic carcinoma.
Author: Sun, Cheng-Yi|Wang, Bai-Lin|Hu, Chao-Quan|Peng, Rui-Yun|Gao, Ya-Bing|Gu, Qing-Yang|Wang, De-Wen
PMID: 14612291
Journal: Proc Natl Acad Sci U S A. 2003 Jan 7;100(1):155-60.
Title: Somatostatin receptor subtype 2 sensitizes human pancreatic cancer cells to death ligand-induced apoptosis.
Author: Guillermet, Julie|Saint-Laurent, Nathalie|Rochaix, Philippe|Cuvillier, Olivier|Levade, Thierry|Schally, Andrew V|Pradayrol, Lucien|Buscail, Louis|Susini, Christiane|Bousquet, Corinne
PMID: 12490654
Journal: Oncogene. 2003 Mar 6;22(9):1365-70.
Title: Inhibition of constitutive NF-kappa B activity by I kappa B alpha M suppresses tumorigenesis.
Author: Fujioka, Shuichi|Sclabas, Guido M|Schmidt, Christian|Niu, Jiangong|Frederick, Wayne A|Dong, Qiang G|Abbruzzese, James L|Evans, Douglas B|Baker, Cheryl|Chiao, Paul J
PMID: 12618762
Journal: J Cancer Res Clin Oncol. 2003 Jan;129(1):1-11.
Title: Vitamin K(2) selectively induced apoptosis in ovarian TYK-nu and pancreatic MIA PaCa-2 cells out of eight solid tumor cell lines through a mechanism different from geranylgeraniol.
Author: Shibayama-Imazu, Toshiko|Sakairi, Shizuka|Watanabe, Akiko|Aiuchi, Toshihiro|Nakajo, Shigeo|Nakaya, Kazuyasu
PMID: 12618894
Journal: Mol Cell Biochem. 2003 Jan;243(1-2):113-22.
Title: Nicotinamide- and caspase-mediated inhibition of poly(ADP-ribose) polymerase are associated with p53-independent cell cycle (G2) arrest and apoptosis.
Author: Saldeen, Johan|Tillmar, Linda|Karlsson, Ella|Welsh, Nils
PMID: 12619896
Journal: Br J Cancer. 2003 Jul 21;89(2):391-7.
Title: AKT inhibition is associated with chemosensitisation in the pancreatic cancer cell line MIA-PaCa-2.
Author: Fahy, B N|Schlieman, M|Virudachalam, S|Bold, R J
PMID: 12865934
Journal: Pancreas. 2003 Aug;27(2):174-9.
Title: Arsenic trioxide induces apoptosis in pancreatic cancer cells via changes in cell cycle, caspase activation, and GADD expression.
Author: Li, Xinquan|Ding, Xianzhong|Adrian, Thomas E
PMID: 12883267
Journal: Pancreatology. 2003;3(4):293-302.
Title: Effect of FHIT gene replacement on growth, cell cycle and apoptosis in pancreatic cancer cells.
Author: Gopalakrishnan, Velliyur K|Banerjee, Abhijit G|Vishwanatha, Jamboor K
PMID: 12890991
Journal: Anticancer Res. 2003 May-Jun;23(3B):2383-7.
Title: Growth-inhibitory effect of phosphatidylinositol 3-kinase inhibitor on human pancreatic cancer cells and expression of Bcl-2 family.
Author: Katayose, Kozo|Seki, Tetsuya|Ohba, Nobuyuki|Funatomi, Hitoshi|Goto, Noboru|Mitamura, Keiji
PMID: 12894518
Journal: J Surg Res. 2003 Jul;113(1):88-95.
Title: Schedule-dependent molecular effects of the proteasome inhibitor bortezomib and gemcitabine in pancreatic cancer.
Author: Fahy, Bridget N|Schlieman, Michael G|Virudachalam, Subbulakshi|Bold, Richard J
PMID: 12943815
Journal: Ai Zheng. 2003 Jun;22(6):649-52.
Title: [Expression and significance of cyclooxygenase-2 in human pancreatic carcinomas].
Author: Wang, Hai-Xia|Chen, Qi-Kui
PMID: 12948419
Journal: Cesk Patol. 2003 Oct;39(4):168-73.
Title: [Apoptosis and expression of bcl-2 protein in invasive ductal adenocarcinoma of the pancreas].
Author: Brazdil, J|Lukas, Z|Hermanova, M|Pazourkova, M|Ruzicka, M|Habanec, B|Kren, L|Dite, P
PMID: 14663927
Journal: World J Gastroenterol. 2003 Dec;9(12):2745-50.
Title: Oil A induces apoptosis of pancreatic cancer cells via caspase activation, redistribution of cell cycle and GADD expression.
Author: Dong, Mi-Lian|Zhu, Yue-Chun|Hopkins, John V
PMID: 14669326
Journal: J Am Coll Surg. 2004 Apr;198(4):591-9.
Title: Inhibition of AKT abrogates chemotherapy-induced NF-kappaB survival mechanisms: implications for therapy in pancreatic cancer.
Author: Fahy, Bridget N|Schlieman, Michael G|Virudachalam, Subbulakshmi|Bold, Richard J
PMID: 15051014
Journal: Carcinogenesis. 2004 Sep;25(9):1701-9. Epub 2004 Apr 29.
Title: Cell cycle arrest, apoptosis induction and inhibition of nuclear factor kappa B activation in anti-proliferative activity of benzyl isothiocyanate against human pancreatic cancer cells.
Author: Srivastava, Sanjay K|Singh, Shivendra V
PMID: 15117814
Journal: Zhonghua Yi Xue Za Zhi. 2004 May 2;84(9):760-5.
Title: [Mechanisms of inhibition of growth of human pancreatic carcinoma implanted in nude mice by somatostatin receptor subtype 2].
Author: Manoj, Kumar|Liu, Zheng-ren|Tian, Rui|Qin, Ren-yi
PMID: 15200918
Journal: Gut. 2004 Aug;53(8):1159-66.
Title: Altered glucose metabolism and proteolysis in pancreatic cancer cell conditioned myoblasts: searching for a gene expression pattern with a microarray analysis of 5000 skeletal muscle genes.
Author: Basso, D|Millino, C|Greco, E|Romualdi, C|Fogar, P|Valerio, A|Bellin, M|Zambon, C-F|Navaglia, F|Dussini, N|Avogaro, A|Pedrazzoli, S|Lanfranchi, G|Plebani, M
PMID: 15247186
Journal: Pancreas. 2004 Aug;29(2):141-51.
Title: Mechanisms of inhibition of growth of human pancreatic carcinoma implanted in nude mice by somatostatin receptor subtype 2.
Author: Kumar, Manoj|Liu, Zheng-Ren|Thapa, Laxmi|Wang, Da-Yu|Tian, Rui|Qin, Ren-Yi
PMID: 15257106
Journal: World J Gastroenterol. 2004 Sep 15;10(18):2759-61.
Title: Expression of Survivin in pancreatic cancer and its correlation to expression of Bcl-2.
Author: Qiao, Jian-Guo|Zhang, Yu-Qing|Yin, Yu-Chun|Tan, Zui
PMID: 15309737
Journal: Cancer Invest. 2004;22(3):389-400.
Title: Arsenic trioxide causes redistribution of cell cycle, caspase activation, and GADD expression in human colonic, breast, and pancreatic cancer cells.
Author: Li, Xinquan|Ding, Xianzhong|Adrian, Thomas E
PMID: 15493360
Journal: Anticancer Res. 2004 Sep-Oct;24(5A):2601-15.
Title: Acute changes in U937 nuclear Ca2+ preceding type 1 "apoptotic" programmed cell death due to MK 886.
Author: Anderson, K M|Rubenstein, M|Alrefai, W A|Dudeja, P|Tsui, P|Harris, J E
PMID: 15517864
Journal: Cancer Res. 2005 Mar 15;65(6):2344-52.
Title: Predominant Bcl-XL knockdown disables antiapoptotic mechanisms: tumor necrosis factor-related apoptosis-inducing ligand-based triple chemotherapy overcomes chemoresistance in pancreatic cancer cells in vitro.
Author: Bai, Jirong|Sui, Jianhua|Demirjian, Aram|Vollmer, Charles M Jr|Marasco, Wayne|Callery, Mark P
PMID: 15781649
Journal: Mod Pathol. 2005 Sep;18(9):1211-6.
Title: Cellular hamartoma resembling gastrointestinal stromal tumor: a solid tumor of the pancreas expressing c-kit (CD117).
Author: Pauser, Ursula|da Silva, Maria T S|Placke, Jorg|Klimstra, David S|Kloppel, Gunter
PMID: 15803185
Journal: World J Gastroenterol. 2005 Apr 14;11(14):2101-8.
Title: Chromic-P32 phosphate treatment of implanted pancreatic carcinoma: mechanism involved.
Author: Liu, Lu|Feng, Guo-Sheng|Gao, Hong|Tong, Guan-Sheng|Wang, Yu|Gao, Wen|Huang, Ying|Li, Cheng
PMID: 15810075
Journal: Clin Cancer Res. 2005 Apr 15;11(8):3094-101.
Title: Intrinsic chemoresistance to gemcitabine is associated with decreased expression of BNIP3 in pancreatic cancer.
Author: Akada, Masanori|Crnogorac-Jurcevic, Tatjana|Lattimore, Samuel|Mahon, Patrick|Lopes, Rita|Sunamura, Makoto|Matsuno, Seiki|Lemoine, Nicholas R
PMID: 15837765
Journal: Pancreas. 2005 May;30(4):337-42.
Title: Bcl-XL protein levels determine apoptotic index in pancreatic carcinoma.
Author: Sharma, Jyotika|Srinivasan, Radhika|Majumdar, Siddhartha|Mir, Snober|Radotra, Bishan Dass|Wig, Jai Dev
PMID: 15841044
Journal: World J Gastroenterol. 2005 May 14;11(18):2744-7.
Title: Clinicopathological significance of Bcl-2 and Bax protein expression in human pancreatic cancer.
Author: Dong, Ming|Zhou, Jian-Ping|Zhang, Hao|Guo, Ke-Jian|Tian, Yu-Lin|Dong, Yu-Ting
PMID: 15884114
Journal: J Gastroenterol Hepatol. 2005 Jul;20(7):1046-53.
Title: Neutral lipid isolated from endosperm of Job's tears inhibits the growth of pancreatic cancer cells via apoptosis, G2/M arrest, and regulation of gene expression.
Author: Bao, Ying|Yuan, Yaozong|Xia, Lu|Jiang, Hua|Wu, Weirong|Zhang, Xuejun
PMID: 15955213
Journal: Oncogene. 2005 Nov 17;24(51):7552-66.
Title: Unique aspects of mda-7/IL-24 antitumor bystander activity: establishing a role for secretion of MDA-7/IL-24 protein by normal cells.
Author: Su, Zhaozhong|Emdad, Luni|Sauane, Moira|Lebedeva, Irina V|Sarkar, Devanand|Gupta, Pankaj|James, C David|Randolph, Aaron|Valerie, Kirstoffer|Walter, Mark R|Dent, Paul|Fisher, Paul B
PMID: 16044151
Journal: Mol Cancer Ther. 2005 Aug;4(8):1222-30.
Title: Histone deacetylase inhibitors induced caspase-independent apoptosis in human pancreatic adenocarcinoma cell lines.
Author: Garcia-Morales, Pilar|Gomez-Martinez, Angeles|Carrato, Alfredo|Martinez-Lacaci, Isabel|Barbera, Victor M|Soto, Jose L|Carrasco-Garcia, Estefania|Menendez-Gutierrez, Maria P|Castro-Galache, Maria D|Ferragut, Jose A|Saceda, Miguel
PMID: 16093438
Journal: Gut. 2005 Sep;54(9):1298-308.
Title: Variants of bcl-2 specific siRNA for silencing antiapoptotic bcl-2 in pancreatic cancer.
Author: Ocker, M|Neureiter, D|Lueders, M|Zopf, S|Ganslmayer, M|Hahn, E G|Herold, C|Schuppan, D
PMID: 16099798
Journal: Biochim Biophys Acta. 2005 Sep 30;1745(3):318-29.
Title: Sodium butyrate sensitises human pancreatic cancer cells to both the intrinsic and the extrinsic apoptotic pathways.
Author: Natoni, Federica|Diolordi, Laura|Santoni, Claudio|Gilardini Montani, Maria Saveria
PMID: 16109447
Journal: Clin Cancer Res. 2005 Aug 15;11(16):6075-86.
Title: Overexpression of cyclin D1 promotes tumor cell growth and confers resistance to cisplatin-mediated apoptosis in an elastase-myc transgene-expressing pancreatic tumor cell line.
Author: Biliran, Hector Jr|Wang, Yong|Banerjee, Sanjeev|Xu, Haiming|Heng, Henry|Thakur, Archana|Bollig, Aliccia|Sarkar, Fazlul H|Liao, Joshua D
PMID: 16115953
Journal: Eur J Cancer. 2005 Oct;41(15):2213-36.
Title: Molecular prognostic markers in pancreatic cancer: a systematic review.
Author: Garcea, G|Neal, C P|Pattenden, C J|Steward, W P|Berry, D P
PMID: 16146690
Journal: Pancreas. 2005 Nov;31(4):317-24.
Title: Nonpeptidic small-molecule inhibitor of Bcl-2 and Bcl-XL, (-)-Gossypol, enhances biological effect of genistein against BxPC-3 human pancreatic cancer cell line.
Author: Mohammad, Ramzi M|Wang, Shaomeng|Banerjee, Sanjeev|Wu, Xihan|Chen, Jianyong|Sarkar, Fazlul H
PMID: 16258364
Journal: Cancer Lett. 2006 Jun 8;237(1):143-54.
Title: SK-7041, a new histone deacetylase inhibitor, induces G2-M cell cycle arrest and apoptosis in pancreatic cancer cell lines.
Author: Ryu, Ji Kon|Lee, Woo Jin|Lee, Kwang Hyuck|Hwang, Jin-Hyeok|Kim, Yong-Tae|Yoon, Yong Bum|Kim, Chung Yong
PMID: 16009488
Journal: J Cell Biochem. 2006 Jan 1;97(1):98-108.
Title: Apoptotic index or a combination of Bax/Bcl-2 expression correlate with survival after resection of pancreatic adenocarcinoma.
Author: Magistrelli, Paolo|Coppola, Roberto|Tonini, Giuseppe|Vincenzi, Bruno|Santini, Daniele|Borzomati, Domenico|Vecchio, Fabio|Valeri, Sergio|Castri, Federica|Antinori, Armando|Nuzzo, Gennaro|Caraglia, Michele|Picciocchi, Aurelio
PMID: 16173075
Journal: Pancreas. 2006 Jan;32(1):93-100.
Title: Investigation of the mechanisms by which EB1089 abrogates apoptosis induced by 9-cis retinoic acid in pancreatic cancer cells.
Author: Mouratidis, Petros X E|Dalgleish, Angus G|Colston, Kay W
PMID: 16340750
Journal: J Mol Med (Berl). 2006 May;84(5):405-15.
Title: Mechanism of triptolide-induced apoptosis: Effect on caspase activation and Bid cleavage and essentiality of the hydroxyl group of triptolide.
Author: Wang, Xianxi|Matta, Ranyia|Shen, Gang|Nelin, Leif D|Pei, Dehua|Liu, Yusen
PMID: 16385419
Journal: J Biol Chem. 2006 Apr 28;281(17):11923-32. Epub 2006 Jan 30.
Title: PS-341 (bortezomib) induces lysosomal cathepsin B release and a caspase-2-dependent mitochondrial permeabilization and apoptosis in human pancreatic cancer cells.
Author: Yeung, Bonnie H Y|Huang, Der-Chen|Sinicrope, Frank A
PMID: 16446371
Journal: Oncol Rep. 2006 Apr;15(4):843-8.
Title: Anticancer effects of phenoxazine derivatives combined with tumor necrosis factor-related apoptosis-inducing ligand on pancreatic cancer cell lines, KLM-1 and MIA-PaCa-2.
Author: Kato, Seiko|Shirato, Ken|Imaizumi, Kazuhiko|Toyota, Hiroko|Mizuguchi, Junichiro|Odawara, Masato|Che, Xiao-Fang|Akiyama, Shinichi|Abe, Akihisa|Tomoda, Akio
PMID: 16525669
Journal: Mol Cancer Ther. 2006 Mar;5(3):483-93.
Title: Down-regulation of Notch-1 contributes to cell growth inhibition and apoptosis in pancreatic cancer cells.
Author: Wang, Zhiwei|Zhang, Yuxiang|Li, Yiwei|Banerjee, Sanjeev|Liao, Joshua|Sarkar, Fazlul H
PMID: 16546962
Journal: Mol Cancer Ther. 2006 Jun;5(6):1387-95.
Title: Pharmacogenetics of anticancer drug sensitivity in pancreatic cancer.
Author: Giovannetti, Elisa|Mey, Valentina|Nannizzi, Sara|Pasqualetti, Giuseppe|Del Tacca, Mario|Danesi, Romano
PMID: 16818496
Journal: Surgery. 2006 Aug;140(2):149-60.
Title: Bcl-XL antisense oligonucleotides coupled with antennapedia enhances radiation-induced apoptosis in pancreatic cancer.
Author: Masui, Toshihiko|Hosotani, Ryo|Ito, Daisuke|Kami, Kazuhiro|Koizumi, Masayuki|Mori, Tomohiko|Toyoda, Eiji|Nakajima, Sanae|Miyamoto, Yoshiharu|Fujimoto, Koji|Doi, Ryuichiro
PMID: 16904964
Journal: Cancer Biol Ther. 2006 Oct;5(10):1294-303. Epub 2006 Oct 4.
Title: Antagonistic interactions between gemcitabine and 5-fluorouracil in the human pancreatic carcinoma cell line Capan-2.
Author: Bellone, Graziella|Carbone, Anna|Busso, Valeria|Scirelli, Tiziana|Buffolino, Alessandra|Smirne, Carlo|Novarino, Anna|Bertetto, Oscar|Tosetti, Luciano|Emanuelli, Giorgio
PMID: 16929163
Journal: J Surg Res. 2006 Dec;136(2):325-35. Epub 2006 Oct 19.
Title: Mitogen-activated protein kinases and chemoresistance in pancreatic cancer cells.
Author: Zhao, Yupei|Shen, Songjie|Guo, Junchao|Chen, Herbert|Greenblatt, David Yu|Kleeff, Jorg|Liao, Quan|Chen, Ge|Friess, Helmut|Leung, Po Sing
PMID: 17054996
Journal: Mol Cancer Ther. 2006 Dec;5(12):3240-7.
Title: Assessment of celecoxib pharmacodynamics in pancreatic cancer.
Author: Jimeno, Antonio|Amador, Maria Luz|Kulesza, Peter|Wang, Xiaofei|Rubio-Viqueira, Belen|Zhang, Xiangfeng|Chan, Audrey|Wheelhouse, Jenna|Kuramochi, Hidekazu|Tanaka, Koji|Danenberg, Kathleen|Messersmith, Wells A|Almuete, Virna|Hruban, Ralph H|Maitra, Anirban|Y
PMID: 17172427
Journal: Anticancer Res. 2006 Nov-Dec;26(6B):4443-50.
Title: Histamine inhibits cell proliferation and modulates the expression of Bcl-2 family proteins via the H2 receptor in human pancreatic cancer cells.
Author: Cricco, Graciela|Martin, Gabriela|Medina, Vanina|Nunez, Mariel|Mohamad, Nora|Croci, Maximo|Crescenti, Ernesto|Bergoc, Rosa|Rivera, Elena
PMID: 17201167
Journal: Int J Cancer. 2007 Feb 15;120(4):734-42.
Title: A novel copper complex of 3-benzoyl-alpha methyl benzene acetic acid with antitumor activity mediated via cyclooxygenase pathway.
Author: Ahmed, Fakhara|Adsule, Shreelekha|Ali, Ashhar S|Banerjee, Sanjeev|Ali, Shadan|Kulkarni, Sudhir|Padhye, Subhash|Sarkar, Fazlul H
PMID: 17131340
Journal: Methods Mol Biol. 2007;361:163-85.
Title: Antisense oligonucleotides: target validation and development of systemically delivered therapeutic nanoparticles.
Author: Zhang, Chuanbo|Pei, Jin|Kumar, Deepak|Sakabe, Isamu|Boudreau, Howard E|Gokhale, Prafulla C|Kasid, Usha N
PMID: 17172711
Journal: Scand J Gastroenterol. 2007 Jan;42(1):103-16.
Title: Apoptosis, proliferation and differentiation patterns are influenced by Zebularine and SAHA in pancreatic cancer models.
Author: Neureiter, Daniel|Zopf, Steffen|Leu, Thorsten|Dietze, Otto|Hauser-Kronberger, Cornelia|Hahn, Eckhart G|Herold, Christoph|Ocker, Matthias
PMID: 17190770
Journal: Anticancer Res. 2007 Jan-Feb;27(1A):23-6.
Title: Tumour suppressor protein (p53), apoptosis inhibiting protein (Bcl-2) and proliferating cell nuclear antigen (PCNA) expressions in a rat pancreatic tumour model.
Author: Makinen, Kimmo|Loimas, Sami|Hakala, Tapio|Eskelinen, Matti
PMID: 17352211
Journal: Proc Natl Acad Sci U S A. 2007 Mar 20;104(12):5103-8. Epub 2007 Mar 19.
Title: Sonic hedgehog acts at multiple stages during pancreatic tumorigenesis.
Author: Morton, Jennifer P|Mongeau, Michelle E|Klimstra, David S|Morris, John P|Lee, Yie Chia|Kawaguchi, Yoshiya|Wright, Christopher V E|Hebrok, Matthias|Lewis, Brian C
PMID: 17372229
Journal: J Cell Mol Med. 2007 Mar-Apr;11(2):349-61.
Title: bcl-2-specific siRNAs restore gemcitabine sensitivity in human pancreatic cancer cells.
Author: Okamoto, Kinya|Ocker, Matthias|Neureiter, Daniel|Dietze, Otto|Zopf, Steffen|Hahn, Eckhart G|Herold, Christoph
PMID: 17378914
Journal: Anticancer Drugs. 2007 Jun;18(5):535-41.
Title: Leukotriene B4 receptor antagonist LY293111 induces S-phase cell cycle arrest and apoptosis in human pancreatic cancer cells.
Author: Tong, Wei-Gang|Ding, Xian-Zhong|Talamonti, Mark S|Bell, Richard H|Adrian, Thomas E
PMID: 17414622
Journal: Biochim Biophys Acta. 2007 Jul;1770(7):1021-7. Epub 2007 Mar 15.
Title: Suppression of 5-lipoxygenase gene is involved in triptolide-induced apoptosis in pancreatic tumor cell lines.
Author: Zhou, G X|Ding, X L|Huang, J F|Zhang, H|Wu, S B
PMID: 17434678
Journal: Cancer Res. 2007 Apr 15;67(8):3853-61.
Title: Curcumin potentiates antitumor activity of gemcitabine in an orthotopic model of pancreatic cancer through suppression of proliferation, angiogenesis, and inhibition of nuclear factor-kappaB-regulated gene products.
Author: Kunnumakkara, Ajaikumar B|Guha, Sushovan|Krishnan, Sunil|Diagaradjane, Parmeswaran|Gelovani, Juri|Aggarwal, Bharat B
PMID: 17440100
Journal: Cancer Lett. 2007 Sep 8;254(2):288-97.
Title: FTY720, a synthetic compound from Isaria sinclairii, inhibits proliferation and induces apoptosis in pancreatic cancer cells.
Author: Shen, Yan|Cai, Minxia|Xia, Weiliang|Liu, Junwei|Zhang, Qiyi|Xie, Haiyang|Wang, Chen|Wang, Xiaohui|Zheng, Shusen
PMID: 17462818
Journal: Cancer Res. 2007 Jul 1;67(13):6278-85.
Title: Repression of BCL2 by the tumor suppressor activity of the lysyl oxidase propeptide inhibits transformed phenotype of lung and pancreatic cancer cells.
Author: Wu, Min|Min, Chengyin|Wang, Xiaobo|Yu, Ziyang|Kirsch, Kathrin H|Trackman, Philip C|Sonenshein, Gail E
PMID: 17616686
Journal: Int J Surg Pathol. 2007 Jul;15(3):311-4.
Title: Solitary fibrous tumor of the pancreas: a case report.
Author: Miyamoto, Hiroshi|Molena, Daniela A|Schoeniger, Luke O|Haodong Xu
PMID: 17652547
Journal: Int J Oncol. 2007 Sep;31(3):567-76.
Title: The combination of the histone-deacetylase inhibitor trichostatin A and gemcitabine induces inhibition of proliferation and increased apoptosis in pancreatic carcinoma cells.
Author: Gahr, Susanne|Ocker, Matthias|Ganslmayer, Marion|Zopf, Steffen|Okamoto, Kinya|Hartl, Andrea|Leitner, Sandra|Hahn, Eckhart G|Herold, Christoph
PMID: 17671683
Journal: Anticancer Res. 2007 Jul-Aug;27(4B):2523-7.
Title: Immunohistochemical expression and prognostic significance of fatty acid synthase in pancreatic carcinoma.
Author: Alo, Piero L|Amini, Mostafa|Piro, Francesca|Pizzuti, Laura|Sebastiani, Valeria|Botti, Claudio|Murari, Riccardo|Zotti, Giancarlo|Di Tondo, Ugo
PMID: 17695548
Journal: Cancer Biol Ther. 2007 Aug;6(8):1173-80. Epub 2007 Apr 29.
Title: Neuropilin-1 interacts with integrin beta1 and modulates pancreatic cancer cell growth, survival and invasion.
Author: Fukasawa, Mitsuharu|Matsushita, Akira|Korc, Murray
PMID: 17726369
Journal: Cancer Sci. 2007 Nov;98(11):1706-13.
Title: CCAAT/enhancer binding protein-beta promotes the survival of intravascular rat pancreatic tumor cells via antiapoptotic effects.
Author: Shimizu, Yasuhito|Kishimoto, Takashi|Ohtsuka, Masayuki|Kimura, Fumio|Shimizu, Hiroaki|Yoshidome, Hiroyuki|Miyazaki, Masaru
PMID: 17727681
Journal: J Cell Biochem. 2007 Dec 1;102(5):1171-9.
Title: BCL-2 functions as an activator of the AKT signaling pathway in pancreatic cancer.
Author: Mortenson, Melinda M|Galante, Joseph G|Gilad, Oren|Schlieman, Michael G|Virudachalam, Subbulakshmi|Kung, Hsing-Jien|Bold, Richard J
PMID: 17960583
Journal: Am Surg. 2007 Dec;73(12):1284-7.
Title: Rare case of Castleman disease involving the pancreas.
Author: Tunru-Dinh, Vonny W|Ghani, Abdul|Tom, Yuel D
PMID: 18186391
Journal: J Surg Res. 2008 Mar;145(1):111-23. Epub 2007 Aug 22.
Title: Effects of the proteasome inhibitor bortezomib on gene expression profiles of pancreatic cancer cells.
Author: Tang, Zhi-Yu|Wu, Yu-Lian|Gao, Shun-Liang|Shen, Hong-Wei
PMID: 17714734
Journal: Biochem Pharmacol. 2008 Feb 15;75(4):836-46.
Title: The immunocytokine scFv23/TNF targeting HER-2/neu induces synergistic cytotoxic effects with 5-fluorouracil in TNF-resistant pancreatic cancer cell lines.
Author: Lyu, Mi-Ae|Kurzrock, Razelle|Rosenblum, Michael G
PMID: 18082672
Journal: World J Gastroenterol. 2008 Mar 14;14(10):1504-9.
Title: Apoptosis of human pancreatic cancer cells induced by Triptolide.
Author: Zhou, Guo-Xiong|Ding, Xiao-Ling|Huang, Jie-Fei|Zhang, Hong|Wu, Sheng-Bao|Cheng, Jian-Ping|Wei, Qun
PMID: 18330938
Journal: Chembiochem. 2008 May 5;9(7):1082-92.
Title: Naturally occurring small-molecule inhibitors of hedgehog/GLI-mediated transcription.
Author: Hosoya, Takahiro|Arai, Midori A|Koyano, Takashi|Kowithayakorn, Thaworn|Ishibashi, Masami
PMID: 18357592
Journal: Cancer Res. 2008 Apr 15;68(8):2803-12.
Title: Targeting CD24 for treatment of colorectal and pancreatic cancer by monoclonal antibodies or small interfering RNA.
Author: Sagiv, Eyal|Starr, Alex|Rozovski, Uri|Khosravi, Rami|Altevogt, Peter|Wang, Timothy|Arber, Nadir
PMID: 18413748
Journal: Cancer Res. 2008 Apr 15;68(8):2944-51.
Title: BH3 mimetic ABT-737 potentiates TRAIL-mediated apoptotic signaling by unsequestering Bim and Bak in human pancreatic cancer cells.
Author: Huang, Shengbing|Sinicrope, Frank A
PMID: 18413764
Journal: Acta Pharmacol Sin. 2008 May;29(5):614-9.
Title: Synergy of gemcitabine and lidamycin associated with NF-kappaB downregulation in pancreatic carcinoma cells.
Author: Chen, Jing|Wu, Shu-Ying|Ou-Yang, Zhi-Gang|Zhen, Yong-Su
PMID: 18430374
Journal: Pancreas. 2008 May;36(4):e15-23.
Title: Inhibition of human pancreatic cell line MIA PaCa2 proliferation by HA-But, a hyaluronic butyric ester: a preliminary report.
Author: Pellizzaro, Cinzia|Speranza, Annalisa|Zorzet, Sonia|Crucil, Ilaria|Sava, Gianni|Scarlata, Ignazio|Cantoni, Silvia|Fedeli, Maya|Coradini, Danila
PMID: 18437074
Journal: J Med Chem. 2008 Jun 12;51(11):3094-103.
Title: Benzoylurea derivatives as a novel class of antimitotic agents: synthesis, anticancer activity, and structure-activity relationships.
Author: Song, Dan-Qing|Wang, Yan|Wu, Lian-Zong|Yang, Peng|Wang, Yue-Ming|Gao, Li-Mei|Li, Yan|Qu, Jing-Rong|Wang, Yong-Hong|Li, Ying-Hong|Du, Na-Na|Han, Yan-Xing|Zhang, Zhi-Ping|Jiang, Jian-Dong
PMID: 18457382
Journal: FASEB J. 2008 Sep;22(9):3358-69.
Title: Human tumor nanoparticles induce apoptosis of pancreatic cancer cells.
Author: Ristorcelli, Elodie|Beraud, Evelyne|Verrando, Patrick|Villard, Claude|Lafitte, Daniel|Sbarra, Veronique|Lombardo, Dominique|Verine, Alain
PMID: 18511551
Journal: Int J Cancer. 2008 Aug 15;123(4):958-66.
Title: TW-37, a small-molecule inhibitor of Bcl-2, inhibits cell growth and invasion in pancreatic cancer.
Author: Wang, Zhiwei|Song, Wen|Aboukameel, Amro|Mohammad, Mussop|Wang, Guoping|Banerjee, Sanjeev|Kong, Dejuan|Wang, Shaomeng|Sarkar, Fazlul H|Mohammad, Ramzi M
PMID: 18528859
Journal: Life Sci. 2008 Aug 15;83(7-8):293-300.
Title: Synergistic effects of multiple natural products in pancreatic cancer cells.
Author: Wang, Zhiwei|Desmoulin, Sita|Banerjee, Sanjeev|Kong, Dejuan|Li, Yiwei|Deraniyagala, Rohan L|Abbruzzese, James|Sarkar, Fazlul H
PMID: 18640131
Journal: JOP. 2008 Jul 10;9(4):526-30.
Title: Solitary fibrous tumor of the pancreas: case report with cytologic and surgical pathology correlation and review of the literature.
Author: Srinivasan, Vidhya D|Wayne, Jeffrey D|Rao, M Sambasiva|Zynger, Debra L
PMID: 18648147
Journal: World J Gastroenterol. 2008 Sep 21;14(35):5403-11.
Title: Anti-tumor activity of erlotinib in the BxPC-3 pancreatic cancer cell line.
Author: Lu, Ying-Ying|Jing, Da-Dao|Xu, Ming|Wu, Kai|Wang, Xing-Peng
PMID: 18803351
Journal: Cancer Res. 2008 Oct 1;68(19):7956-65.
Title: Targeting XIAP bypasses Bcl-2-mediated resistance to TRAIL and cooperates with TRAIL to suppress pancreatic cancer growth in vitro and in vivo.
Author: Vogler, Meike|Walczak, Henning|Stadel, Dominic|Haas, Tobias L|Genze, Felicitas|Jovanovic, Marjana|Gschwend, Jurgen E|Simmet, Thomas|Debatin, Klaus-Michael|Fulda, Simone
PMID: 18829553
Journal: Ann N Y Acad Sci. 2008 Sep;1138:181-98.
Title: Review of the apoptosis pathways in pancreatic cancer and the anti-apoptotic effects of the novel sea cucumber compound, Frondoside A.
Author: Li, X|Roginsky, A B|Ding, X-Z|Woodward, C|Collin, P|Newman, R A|Bell, R H Jr|Adrian, T E
PMID: 18837899
Journal: Bioorg Med Chem. 2008 Nov 1;16(21):9420-4.
Title: Hedgehog/GLI-mediated transcriptional inhibitors from Zizyphus cambodiana.
Author: Arai, Midori A|Tateno, Chikashi|Hosoya, Takahiro|Koyano, Takashi|Kowithayakorn, Thaworn|Ishibashi, Masami
PMID: 18842418
Journal: Cancer Invest. 2008 Oct;26(8):852-9.
Title: Expression of SGLT1, Bcl-2 and p53 in primary pancreatic cancer related to survival.
Author: Casneuf, Veerle F|Fonteyne, Philippe|Van Damme, Nancy|Demetter, Pieter|Pauwels, Patrick|de Hemptinne, Bernard|De Vos, Martine|Van de Wiele, Christophe|Peeters, Marc
PMID: 18853313
Journal: Apoptosis. 2008 Dec;13(12):1465-78.
Title: In vitro and in vivo induction of apoptosis by capsaicin in pancreatic cancer cells is mediated through ROS generation and mitochondrial death pathway.
Author: Zhang, Ruifen|Humphreys, Ian|Sahu, Ravi P|Shi, Yan|Srivastava, Sanjay K
PMID: 19002586
Journal: J Ovarian Res. 2008 Nov 24;1(1):9.
Title: Sensitization of ovarian cancer cells to cisplatin by genistein: the role of NF-kappaB.
Author: Solomon, Leigh A|Ali, Shadan|Banerjee, Sanjeev|Munkarah, Adnan R|Morris, Robert T|Sarkar, Fazlul H
PMID: 19025644
Journal: Cancer Lett. 2009 Mar 18;275(2):247-55.
Title: Inhibition of COX-2 and activation of peroxisome proliferator-activated receptor gamma synergistically inhibits proliferation and induces apoptosis of human pancreatic carcinoma cells.
Author: Sun, Wei-Hao|Chen, Guo-Sheng|Ou, Xi-Long|Yang, Ye|Luo, Cheng|Zhang, Yuan|Shao, Yun|Xu, Hai-Chen|Xiao, Bin|Xue, Yi-Ping|Zhou, Su-Ming|Zhao, Qin-Shi|Ding, Guo-Xian
PMID: 19056168
Journal: J Surg Res. 2009 Mar;152(1):18-25.
Title: ERK/BCL-2 pathway in the resistance of pancreatic cancer to anoikis.
Author: Galante, Joseph M|Mortenson, Melinda M|Bowles, Tawnya L|Virudachalam, Subbulakshmi|Bold, Richard J
PMID: 19062038
Journal: Clin Cancer Res. 2009 Jan 1;15(1):150-9.
Title: BH3 mimetic obatoclax enhances TRAIL-mediated apoptosis in human pancreatic cancer cells.
Author: Huang, Shengbing|Okumura, Kenji|Sinicrope, Frank A
PMID: 19118042
Journal: Mol Cancer Ther. 2009 Feb;8(2):315-23.
Title: Crocetin inhibits pancreatic cancer cell proliferation and tumor progression in a xenograft mouse model.
Author: Dhar, Animesh|Mehta, Smita|Dhar, Gopal|Dhar, Kakali|Banerjee, Snigdha|Van Veldhuizen, Peter|Campbell, Donald R|Banerjee, Sushanta K
PMID: 19208826
Journal: Anticancer Drugs. 2009 Feb;20(2):131-40.
Title: Dihydroartemisinin inhibits growth of pancreatic cancer cells in vitro and in vivo.
Author: Chen, Hua|Sun, Bei|Pan, Shangha|Jiang, Hongchi|Sun, Xueying
PMID: 19209030
Journal: PLoS One. 2009;4(2):e4455.
Title: Genetic ablation of Bcl-x attenuates invasiveness without affecting apoptosis or tumor growth in a mouse model of pancreatic neuroendocrine cancer.
Author: Hager, Jeffrey H|Ulanet, Danielle B|Hennighausen, Lothar|Hanahan, Douglas
PMID: 19209227
Journal: World J Gastroenterol. 2009 Mar 7;15(9):1065-71.
Title: Aminoguanidine impedes human pancreatic tumor growth and metastasis development in nude mice.
Author: Mohamad, Nora A|Cricco, Graciela P|Sambuco, Lorena A|Croci, Maximo|Medina, Vanina A|Gutierrez, Alicia S|Bergoc, Rosa M|Rivera, Elena S|Martin, Gabriela A
PMID: 19266598
Journal: Cancer Lett. 2009 Aug 18;281(1):42-52.
Title: Bruceine D induces apoptosis in pancreatic adenocarcinoma cell line PANC-1 through the activation of p38-mitogen activated protein kinase.
Author: Lau, Sin Ting|Lin, Zhi-Xiu|Liao, Yonghong|Zhao, Ming|Cheng, Christopher H K|Leung, Po Sing
PMID: 19286308
Journal: Cancer Res. 2009 Apr 1;69(7):2757-65.
Title: TW-37, a small-molecule inhibitor of Bcl-2, inhibits cell growth and induces apoptosis in pancreatic cancer: involvement of Notch-1 signaling pathway.
Author: Wang, Zhiwei|Azmi, Asfar Sohail|Ahmad, Aamir|Banerjee, Sanjeev|Wang, Shaomeng|Sarkar, Fazlul H|Mohammad, Ramzi M
PMID: 19318573
Journal: J Biol Chem. 2009 Jun 26;284(26):17868-76.
Title: Interleukin-32 expression in the pancreas.
Author: Nishida, Atsushi|Andoh, Akira|Inatomi, Osamu|Fujiyama, Yoshihide
PMID: 19386602
Journal: Mol Pharmacol. 2009 Aug;76(2):327-41.
Title: BCL-2 family inhibitors enhance histone deacetylase inhibitor and sorafenib lethality via autophagy and overcome blockade of the extrinsic pathway to facilitate killing.
Author: Martin, Aditi Pandya|Park, Margaret A|Mitchell, Clint|Walker, Teneille|Rahmani, Mohamed|Thorburn, Andrew|Haussinger, Dieter|Reinehr, Roland|Grant, Steven|Dent, Paul
PMID: 19483105
Journal: Biochem Biophys Res Commun. 2009 Aug 14;386(1):35-9.
Title: Endocrine glands-derived vascular endothelial growth factor protects pancreatic cancer cells from apoptosis via upregulation of the myeloid cell leukemia-1 protein.
Author: Ren, Li-Nan|Li, Qing-Fang|Xiao, Feng-Jun|Yan, Jun|Yang, Yue-Feng|Wang, Li-Sheng|Guo, Xiao-Zhong|Wang, Hua
PMID: 19523441
Journal: Cancer Res. 2009 Jul 1;69(13):5575-83.
Title: Antitumor activity of gemcitabine and oxaliplatin is augmented by thymoquinone in pancreatic cancer.
Author: Banerjee, Sanjeev|Kaseb, Ahmed O|Wang, Zhiwei|Kong, Deujan|Mohammad, Mussop|Padhye, Subhash|Sarkar, Fazlul H|Mohammad, Ramzi M
PMID: 19549912
Journal: Nihon Shokakibyo Gakkai Zasshi. 2009 Jul;106(7):1078-85.
Title: [A case of solitary fibrous tumor of the pancreas].
Author: Ishiwatari, Hirotoshi|Hayashi, Tsuyoshi|Yoshida, Makoto|Kuroiwa, Ganji|Sato, Yasushi|Kobune, Masayoshi|Takimoto, Rishu|Kimura, Yasutoshi|Hasegawa, Tadashi|Hirata, Koichi|Kato, Junji
PMID: 19578317
Journal: Hepatobiliary Pancreat Dis Int. 2009 Aug;8(4):418-23.
Title: Interstitial chemotherapy with ricin-loaded thermosensitive hydrogel in pancreatic cancer xenograft.
Author: Chen, Zhi-Kui|Lin, Li-Wu|Weng, Xiu-Hua|Xue, En-Sheng|Lin, Yong-Hua
PMID: 19666413
Journal: Oncogene. 2009 Oct 15;28(41):3671-80.
Title: The HIF1alpha-inducible pro-cell death gene BNIP3 is a novel target of SIM2s repression through cross-talk on the hypoxia response element.
Author: Farrall, A L|Whitelaw, M L
PMID: 19668230
Journal: J Biochem. 2009 Dec;146(6):833-8.
Title: PERIOD1 is an anti-apoptotic factor in human pancreatic and hepatic cancer cells.
Author: Sato, Fuyuki|Nagata, Chihiro|Liu, Yang|Suzuki, Takahiro|Kondo, Jun|Morohashi, Satoko|Imaizumi, Tadaatsu|Kato, Yukio|Kijima, Hiroshi
PMID: 19675098
Journal: PLoS One. 2009 Aug 28;4(8):e6816.
Title: MicroRNA miR-34 inhibits human pancreatic cancer tumor-initiating cells.
Author: Ji, Qing|Hao, Xinbao|Zhang, Min|Tang, Wenhua|Yang, Meng|Li, Ling|Xiang, Debing|Desano, Jeffrey T|Bommer, Guido T|Fan, Daiming|Fearon, Eric R|Lawrence, Theodore S|Xu, Liang
PMID: 19714243
Journal: J Carcinog. 2009;8:13.
Title: Gli1 maintains cell survival by up-regulating IGFBP6 and Bcl-2 through promoter regions in parallel manner in pancreatic cancer cells.
Author: Xu, Xuan-Fu|Guo, Chuan-Yong|Liu, Jun|Yang, Wen-Juan|Xia, Yu-Jing|Xu, Ling|Yu, Yong-Chun|Wang, Xing-Peng
PMID: 19736394
Journal: Ann Diagn Pathol. 2009 Oct;13(5):339-43.
Title: Solitary fibrous tumor of the pancreas.
Author: Chetty, Runjan|Jain, Richa|Serra, Stefano
PMID: 19751911
Journal: PLoS One. 2009 Oct 16;4(10):e7495.
Title: The reg4 gene, amplified in the early stages of pancreatic cancer development, is a promising therapeutic target.
Author: Legoffic, Aude|Calvo, Ezequiel|Cano, Carla|Folch-Puy, Emma|Barthet, Marc|Delpero, Jean Robert|Ferres-Maso, Montse|Dagorn, Jean Charles|Closa, Daniel|Iovanna, Juan
PMID: 19834624
Journal: Curr Mol Med. 2009 Sep;9(7):873-86.
Title: Hedgehog target genes: mechanisms of carcinogenesis induced by aberrant hedgehog signaling activation.
Author: Katoh, Y|Katoh, M
PMID: 19860666
Journal: Br J Cancer. 2009 Dec 15;101(12):2005-14.
Title: Glycogen synthase kinase-3: a new therapeutic target in renal cell carcinoma.
Author: Bilim, V|Ougolkov, A|Yuuki, K|Naito, S|Kawazoe, H|Muto, A|Oya, M|Billadeau, D|Motoyama, T|Tomita, Y
PMID: 19920820
Journal: Zhonghua Wai Ke Za Zhi. 2009 Jul 1;47(13):1002-5.
Title: [Study on anticancer effect of dihydroartemisinin on pancreatic cancer].
Author: Chen, Hua|Sun, Bei|Pan, Shang-ha|Li, Jun|Xue, Dong-bo|Meng, Qing-hui|Jiang, Hong-chi
PMID: 19957812
Journal: Mol Ther. 2010 Jan;18(1):188-97.
Title: G-rich oligonucleotides inhibit HIF-1alpha and HIF-2alpha and block tumor growth.
Author: Guan, Yongli|Reddy, Kavitha Ramasamy|Zhu, Qiqing|Li, Yifei|Lee, KangAe|Weerasinghe, Priya|Prchal, Josef|Semenza, Gregg L|Jing, Naijie
PMID: 19755960
Journal: Pancreas. 2010 Apr;39(3):323-31.
Title: Preclinical studies of apogossypolone, a novel pan inhibitor of bcl-2 and mcl-1, synergistically potentiates cytotoxic effect of gemcitabine in pancreatic cancer cells.
Author: Banerjee, Sanjeev|Choi, Minsig|Aboukameel, Amro|Wang, Zhiwei|Mohammad, Mussop|Chen, Jianyong|Yang, Dajun|Sarkar, Fazlul H|Mohammad, Ramzi M
PMID: 19823097
Journal: Cancer Lett. 2010 May 1;291(1):90-8.
Title: Downregulation of nuclear factor-kappaB p65 subunit by small interfering RNA synergizes with gemcitabine to inhibit the growth of pancreatic cancer.
Author: Kong, Rui|Sun, Bei|Jiang, Hongchi|Pan, Shangha|Chen, Hua|Wang, Shuangjia|Krissansen, Geoffrey W|Sun, Xueying
PMID: 19880242
Journal: Int J Cancer. 2010 Jul 15;127(2):257-68.
Title: Resveratrol, a multitargeted agent, can enhance antitumor activity of gemcitabine in vitro and in orthotopic mouse model of human pancreatic cancer.
Author: Harikumar, Kuzhuvelil B|Kunnumakkara, Ajaikumar B|Sethi, Gautam|Diagaradjane, Parmeswaran|Anand, Preetha|Pandey, Manoj K|Gelovani, Juri|Krishnan, Sunil|Guha, Sushovan|Aggarwal, Bharat B
PMID: 19908231
Journal: Acta Pharmacol Sin. 2010 Jan;31(1):73-80.
Title: Aspirin inhibits proliferation of gemcitabine-resistant human pancreatic cancer cells and augments gemcitabine-induced cytotoxicity.
Author: Ou, Yan-qiu|Zhu, Wen bo|Li, Yan|Qiu, Peng-xin|Huang, Yi-jun|Xie, Jun|He, Song-min|Zheng, Xiao-ke|Leng, Tian-dong|Xu, Dong|Yan, Guang-mei
PMID: 19966835
Journal: Mol Cell Biol. 2010 Mar;30(6):1341-56.
Title: Nuclear receptor SHP, a death receptor that targets mitochondria, induces apoptosis and inhibits tumor growth.
Author: Zhang, Yuxia|Soto, Jamie|Park, Kyungtae|Viswanath, Gunda|Kuwada, Scott|Abel, E Dale|Wang, Li
PMID: 20065042
Journal: Cancer Res. 2010 Feb 1;70(3):1130-40.
Title: Silencing of RON receptor signaling promotes apoptosis and gemcitabine sensitivity in pancreatic cancers.
Author: Logan-Collins, Jocelyn|Thomas, Ryan M|Yu, Peter|Jaquish, Dawn|Mose, Evangeline|French, Randall|Stuart, William|McClaine, Rebecca|Aronow, Bruce|Hoffman, Robert M|Waltz, Susan E|Lowy, Andrew M
PMID: 20103639
Journal: Pancreas. 2010 Jul;39(5):581-94.
Title: Blocking angiotensin II Type 1 receptor triggers apoptotic cell death in human pancreatic cancer cells.
Author: Gong, Qiaoke|Davis, Molly|Chipitsyna, Galina|Yeo, Charles J|Arafat, Hwyda A
PMID: 20118823
Journal: Cancer Lett. 2010 Jul 1;293(1):99-108.
Title: Dihydroartemisinin inactivates NF-kappaB and potentiates the anti-tumor effect of gemcitabine on pancreatic cancer both in vitro and in vivo.
Author: Wang, Shuang-Jia|Gao, Yue|Chen, Hua|Kong, Rui|Jiang, Hong-Chi|Pan, Shang-Ha|Xue, Dong-Bo|Bai, Xue-Wei|Sun, Bei
PMID: 20137856
Journal: Int J Cancer. 2010 Sep 1;127(5):1096-105.
Title: The marine compound spongistatin 1 targets pancreatic tumor progression and metastasis.
Author: Rothmeier, Andrea S|Schneiders, Uta M|Wiedmann, Romina M|Ischenko, Ivan|Bruns, Christiane J|Rudy, Anita|Zahler, Stefan|Vollmar, Angelika M
PMID: 20143389
Journal: J Biol Chem. 2010 Apr 9;285(15):11498-507.
Title: Celastrol, a triterpene, enhances TRAIL-induced apoptosis through the down-regulation of cell survival proteins and up-regulation of death receptors.
Author: Sung, Bokyung|Park, Byoungduck|Yadav, Vivek R|Aggarwal, Bharat B
PMID: 20154087
Journal: Pancreas. 2010 Aug;39(6):923-9.
Title: Inhibition of pancreatic cancer cell growth by cucurbitacin B through modulation of signal transducer and activator of transcription 3 signaling.
Author: Zhang, Meixia|Sun, Chunyan|Shan, Xiaolei|Yang, Xiaolin|Li-Ling, Jesse|Deng, Yihui
PMID: 20182390
Journal: Autophagy. 2010 Apr;6(3):322-9. Epub 2010 Apr 26.
Title: Targeting the prodeath and prosurvival functions of autophagy as novel therapeutic strategies in cancer.
Author: Dalby, Kevin N|Tekedereli, Ibrahim|Lopez-Berestein, Gabriel|Ozpolat, Bulent
PMID: 20224296
Journal: J Cell Physiol. 2010 Jul;224(1):94-100.
Title: Characterization of BAG3 cleavage during apoptosis of pancreatic cancer cells.
Author: Wang, Hua-Qin|Meng, Xin|Gao, Yan-Yan|Liu, Bao-Qin|Niu, Xiao-Fang|Zhang, Hai-Yan|Du, Zhen-Xian
PMID: 20232307
Journal: J Cell Physiol. 2010 Jul;224(1):112-9.
Title: Sorafenib combined vitamin K induces apoptosis in human pancreatic cancer cell lines through RAF/MEK/ERK and c-Jun NH2-terminal kinase pathways.
Author: Wei, Gang|Wang, Meifang|Carr, Brian I
PMID: 20301194
Journal: Zhonghua Wai Ke Za Zhi. 2010 Jan 15;48(2):128-33.
Title: [An experimental study of gemcitabine inducing pancreatic cancer cell apoptosis potentiated by nuclear factor-kappa B P65 siRNA].
Author: Kong, Rui|Sun, Bei|Wang, Shuang-jia|Pan, Shang-ha|Wang, Gang|Chen, Hua|Xue, Dong-bo|Jiang, Hong-chi
PMID: 20302733
Journal: Cancer Sci. 2010 May;101(5):1226-33.
Title: Cantharidin, a potent and selective PP2A inhibitor, induces an oxidative stress-independent growth inhibition of pancreatic cancer cells through G2/M cell-cycle arrest and apoptosis.
Author: Li, Wei|Xie, Li|Chen, Zheng|Zhu, Yi|Sun, Yujie|Miao, Yi|Xu, Zekuan|Han, Xiao
PMID: 20331621
Journal: Mol Cancer. 2010 Apr 6;9:73.
Title: Maslinic acid potentiates the anti-tumor activity of tumor necrosis factor alpha by inhibiting NF-kappaB signaling pathway.
Author: Li, Chenghai|Yang, Zhengfeng|Zhai, Chunyan|Qiu, Wenwei|Li, Dali|Yi, Zhengfang|Wang, Lei|Tang, Jie|Qian, Min|Luo, Jian|Liu, Mingyao
PMID: 20367887
Journal: Expert Opin Ther Targets. 2010 Jun;14(6):611-20.
Title: PAR-4 as a possible new target for pancreatic cancer therapy.
Author: Azmi, Asfar S|Philip, Philip A|Zafar, Syed F|Sarkar, Fazlul H|Mohammad, Ramzi M
PMID: 20426700
Journal: Cancer Sci. 2010 Jul;101(7):1754-60.
Title: Bmi-1 is related to proliferation, survival and poor prognosis in pancreatic cancer.
Author: Song, Wenjie|Tao, Kaishan|Li, Haimin|Jin, Chen|Song, Zhenshun|Li, Jun|Shi, Hai|Li, Xiao|Dang, Zheng|Dou, Kefeng
PMID: 20426791
Journal: Gut. 2010 Aug;59(8):1101-10.
Title: CUX1: target of Akt signalling and mediator of resistance to apoptosis in pancreatic cancer.
Author: Ripka, S|Neesse, A|Riedel, J|Bug, E|Aigner, A|Poulsom, R|Fulda, S|Neoptolemos, J|Greenhalf, W|Barth, P|Gress, T M|Michl, P
PMID: 20442202
Journal: J Surg Res. 2010 Oct;163(2):276-81.
Title: Targeting Bcl-2-mediated cell death as a novel therapy in pancreatic cancer.
Author: Muilenburg, Diego J|Coates, Jodi M|Virudachalam, Subbulakshmi|Bold, Richard J
PMID: 20452611
Journal: Pancreas. 2010 Oct;39(7):994-1001.
Title: Upregulated histone deacetylase 1 expression in pancreatic ductal adenocarcinoma and specific siRNA inhibits the growth of cancer cells.
Author: Gao, Dao-Jian|Xu, Min|Zhang, Yu-Qi|Du, Yi-Qi|Gao, Jun|Gong, Yan-Fang|Man, Xiao-Hua|Wu, Hong-Yu|Jin, Jing|Xu, Guo-Ming|Li, Zhao-Shen
PMID: 20467347
Journal: Cancer Biol Ther. 2010 Jul 1;10(1):99-107. Epub 2010 Jul 26.
Title: Combination effects of bortezomib with gemcitabine and EMAP II in experimental pancreatic cancer.
Author: Awasthi, Niranjan|Schwarz, Margaret A|Schwarz, Roderich E
PMID: 20495354
Journal: Acta Pharmacol Sin. 2010 Jun;31(6):741-5.
Title: Gemcitabine combined with gum mastic causes potent growth inhibition and apoptosis of pancreatic cancer cells.
Author: Huang, Xin-yu|Wang, Hong-cheng|Yuan, Zhou|Li, Ang|He, Mei-lan|Ai, Kai-xing|Zheng, Qi|Qin, Huan-long
PMID: 20523344
Journal: J Dig Dis. 2010 Jun;11(3):176-84.
Title: Knockdown of hTERT by SiRNA suppresses growth of Capan-2 human pancreatic cancer cell via the inhibition of expressions of Bcl-2 and COX-2.
Author: Zhong, Ying Qiang|Xia, Zhong Sheng|Fu, Yu Ru|Zhu, Zhao Hua
PMID: 20579221
Journal: Br J Pharmacol. 2010 Jun;160(4):998-1007.
Title: Cucurbitacin B, a novel in vivo potentiator of gemcitabine with low toxicity in the treatment of pancreatic cancer.
Author: Iwanski, Gabriela B|Lee, Dhong H|En-Gal, Shlomit|Doan, Ngan B|Castor, Brandon|Vogt, Marco|Toh, Melvin|Bokemeyer, Carsten|Said, Jonathan W|Thoennissen, Nils H|Koeffler, H Phillip
PMID: 20590594
Journal: J Pineal Res. 2010 Oct;49(3):248-55.
Title: Melatonin induces pro-apoptotic signaling pathway in human pancreatic carcinoma cells (PANC-1).
Author: Leja-Szpak, Anna|Jaworek, Jolanta|Pierzchalski, Piotr|Reiter, Russel J
PMID: 20626591
Journal: BMC Cancer. 2010 Jul 20;10:379.
Title: Simultaneous gene silencing of Bcl-2, XIAP and Survivin re-sensitizes pancreatic cancer cells towards apoptosis.
Author: Ruckert, Felix|Samm, Nicole|Lehner, Anne-Kathrin|Saeger, Hans-Detlev|Grutzmann, Robert|Pilarsky, Christian
PMID: 20646298
Journal: Zhonghua Wai Ke Za Zhi. 2010 Apr 1;48(7):530-4.
Title: [Experimental study of the function and mechanism combining dihydroartemisinin and gemcitabine in treating pancreatic cancer].
Author: Wang, Shuang-jia|Sun, Bei|Pan, Shang-ha|Chen, Hua|Kong, Rui|Li, Jun|Xue, Dong-bo|Bai, Xue-wei|Jiang, Hong-chi
PMID: 20646665
Journal: Cancer Res. 2010 Sep 1;70(17):6824-36.
Title: Inactivation of the orphan nuclear receptor TR3/Nur77 inhibits pancreatic cancer cell and tumor growth.
Author: Lee, Syng-Ook|Abdelrahim, Maen|Yoon, Kyungsil|Chintharlapalli, Sudhakar|Papineni, Sabitha|Kim, Kyounghyun|Wang, Huamin|Safe, Stephen
PMID: 20660371
Journal: J Exp Clin Cancer Res. 2010 Aug 10;29:108.
Title: Parthenolide induces proliferation inhibition and apoptosis of pancreatic cancer cells in vitro.
Author: Liu, Jun-Wei|Cai, Min-Xia|Xin, Ying|Wu, Qing-Song|Ma, Jun|Yang, Po|Xie, Hai-Yang|Huang, Dong-Sheng
PMID: 20698986
Journal: Cancer Res. 2010 Nov 1;70(21):8695-705.
Title: {Gamma}-tocotrienol inhibits pancreatic tumors and sensitizes them to gemcitabine treatment by modulating the inflammatory microenvironment.
Author: Kunnumakkara, Ajaikumar B|Sung, Bokyung|Ravindran, Jayaraj|Diagaradjane, Parmeswaran|Deorukhkar, Amit|Dey, Sanjit|Koca, Cemile|Yadav, Vivek R|Tong, Zhimin|Gelovani, Juri G|Guha, Sushovan|Krishnan, Sunil|Aggarwal, Bharat B
PMID: 20864511
Journal: Biol Pharm Bull. 2010;33(10):1740-5.
Title: Matrine inhibits proliferation and induces apoptosis of pancreatic cancer cells in vitro and in vivo.
Author: Liu, Tianyou|Song, Yan|Chen, Hua|Pan, Shangha|Sun, Xueying
PMID: 20930385
Journal: Phytother Res. 2010 Nov;24(11):1637-44.
Title: Antiproliferative effect of resveratrol in pancreatic cancer cells.
Author: Cui, Jing|Sun, Renhu|Yu, Yangping|Gou, Shanmiao|Zhao, Gang|Wang, Chunyou
PMID: 21031621
Journal: Zhongguo Zhong Yao Za Zhi. 2010 Nov;35(22):3056-9.
Title: [Influence of betulinic acid on proliferation, migration, cell cycle and apoptosis of pancreatic cancer cells].
Author: Jiang, Mengjun|Zhou, Yaoyuan|Yang, Min|Zhang, Rongjun|Zou, Meifen|Cai, Gangming|Pan, Donghui
PMID: 21355282
Journal: Mol Med Rep. 2010 Jul-Aug;3(4):699-704.
Title: Reduction of pancreatic cancer cell viability and induction of apoptosis mediated by siRNA targeting DNMT1 through suppression of total DNA methyltransferase activity.
Author: Xu, Min|Gao, Jun|Du, Yi Qi|Gao, Dao-Jian|Zhang, Yu Qi|Li, Zhao Shen|Zhang, You Li|Gong, Yan Fang|Xu, Ping
PMID: 21472302
Journal: Oncol Lett. 2010 May;1(3):565-568.
Title: MicroRNA-mediated regulation of pancreatic cancer cell proliferation.
Author: Basu, Aruna|Jiang, Xin|Negrini, Massimo|Haldar, Subrata
PMID: 22966344
Journal: Cancers (Basel). 2010 Dec 23;3(1):1-16.
Title: The role of apoptosis in the pathology of pancreatic cancer.
Author: Samm, Nicole|Werner, Kristin|Ruckert, Felix|Saeger, Hans Detlev|Grutzmann, Robert|Pilarsky, Christian
PMID: 24212603
Journal: Dig Dis Sci. 2011 Mar;56(3):741-50.
Title: Pancreatic cancer cells resistant to chemoradiotherapy rich in "stem-cell-like" tumor cells.
Author: Du, Zhiyong|Qin, Renyi|Wei, Cuifeng|Wang, Min|Shi, Chengjian|Tian, Rui|Peng, Chenghong
PMID: 20683663
Journal: Gene Ther. 2011 Jan;18(1):73-81.
Title: E-cadherin contributes to the bystander effect of TK/GCV suicide therapy and enhances its antitumoral activity in pancreatic cancer models.
Author: Garcia-Rodriguez, L|Abate-Daga, D|Rojas, A|Gonzalez, J R|Fillat, C
PMID: 20720574
Journal: Mol Biol Rep. 2011 Nov;38(8):4903-11.
Title: The neuronal pentraxin II gene (NPTX2) inhibit proliferation and invasion of pancreatic cancer cells in vitro.
Author: Zhang, Ling|Gao, Jun|Li, Lei|Li, Zhaoshen|Du, Yiqi|Gong, Yanfang
PMID: 21161403
Journal: Org Biomol Chem. 2011 Feb 21;9(4):1133-9.
Title: New hedgehog/GLI-signaling inhibitors from Adenium obesum.
Author: Arai, Midori A|Tateno, Chikashi|Koyano, Takashi|Kowithayakorn, Thaworn|Kawabe, Seiichiro|Ishibashi, Masami
PMID: 21170436
Journal: Recent Pat DNA Gene Seq. 2011 Apr;5(1):28-34.
Title: Recent patents concerning targeted therapy of apoptosis resistance in pancreatic cancer.
Author: Werner, Kristin|Ruckert, Felix|Saeger, Hans-Detlev|Grutzmann, Robert|Pilarsky, Christian
PMID: 21194411
Journal: Front Biosci (Elite Ed). 2011 Jan 1;3:515-28.
Title: Sulforaphane synergizes with quercetin to inhibit self-renewal capacity of pancreatic cancer stem cells.
Author: Srivastava, Rakesh K|Tang, Su-Ni|Zhu, Wenyu|Meeker, Daniel|Shankar, Sharmila
PMID: 21196331
Journal: J Nat Prod. 2011 Feb 25;74(2):137-44.
Title: Cytotoxic and apoptosis-inducing activities of triterpene acids from Poria cocos.
Author: Kikuchi, Takashi|Uchiyama, Emiko|Ukiya, Motohiko|Tabata, Keiichi|Kimura, Yumiko|Suzuki, Takashi|Akihisa, Toshihiro
PMID: 21250700
Journal: Biomed Pharmacother. 2011 Mar;65(2):123-31.
Title: Promoted cancer growth by stimulating cell proliferation and decreasing apoptosis using a lentivirus-based EphB2 RNAi in pancreatic carcinoma CFPAC-1 cells.
Author: Hua, Yong-qiang|Ouyang, Hua-qiang|Chen, Zhen|Meng, Zhi-qiang|Luo, Jian-min|Lin, Jun-hua|Zhou, Zhen-hua|Chen, Hao|Wang, Kun|Liu, Lu-ming
PMID: 21292437
Journal: PLoS One. 2011 Jan 31;6(1):e16530.
Title: Resveratrol inhibits pancreatic cancer stem cell characteristics in human and KrasG12D transgenic mice by inhibiting pluripotency maintaining factors and epithelial-mesenchymal transition.
Author: Shankar, Sharmila|Nall, Dara|Tang, Su-Ni|Meeker, Daniel|Passarini, Jenna|Sharma, Jay|Srivastava, Rakesh K
PMID: 21304978
Journal: Oncol Rep. 2011 May;25(5):1253-61.
Title: Enhanced effect of gemcitabine by emodin against pancreatic cancer in vivo via cytochrome C-regulated apoptosis.
Author: Chen, Hui|Wei, Weitian|Guo, Yafei|Liu, An|Tong, Hongfei|Wang, Zhaohong|Tan, Wei|Liu, Jinxiang|Lin, Shengzhang
PMID: 21305255
Journal: Arch Med Res. 2011 Jan;42(1):8-14.
Title: Bcl-2 upregulation induced by miR-21 via a direct interaction is associated with apoptosis and chemoresistance in MIA PaCa-2 pancreatic cancer cells.
Author: Dong, Jie|Zhao, Yu-Pei|Zhou, Li|Zhang, Tai-Ping|Chen, Ge
PMID: 21376256
Journal: Br J Cancer. 2011 Apr 26;104(9):1440-51.
Title: Meta-analysis of immunohistochemical prognostic markers in resected pancreatic cancer.
Author: Smith, R A|Tang, J|Tudur-Smith, C|Neoptolemos, J P|Ghaneh, P
PMID: 21448172
Journal: Pathol Res Pract. 2011 Jun 15;207(6):343-53.
Title: Dysregulation of the cell cycle and chromosomal imbalances in juxtaglomerular cell tumors - a comparative study with endocrine tumors of the pancreas.
Author: Assmann, Gerald|Verdorfer, Irmgard|Jung, Andreas|Bader, Markus|Muller-Hocker, Josef
PMID: 21482036
Journal: Carcinogenesis. 2011 Jul;32(7):1013-24.
Title: Mesothelin overexpression promotes autocrine IL-6/sIL-6R trans-signaling to stimulate pancreatic cancer cell proliferation.
Author: Bharadwaj, Uddalak|Marin-Muller, Christian|Li, Min|Chen, Changyi|Yao, Qizhi
PMID: 21515913
Journal: Yao Xue Xue Bao. 2011 Feb;46(2):146-52.
Title: [Role of nuclear factor-kappaB on emodin-induced sensitization of pancreatic cancer to gemcitabine].
Author: Liu, An|Hu, Yun-shuang|Wang, Zhao-hong|Tang, Li-li|Ke, Pin-yu|Lin, Sheng-zhang
PMID: 21542284
Journal: Eur J Pharmacol. 2011 Aug 31;665(1-3):1-7.
Title: beta2-adrenoceptor blocker synergizes with gemcitabine to inhibit the proliferation of pancreatic cancer cells via apoptosis induction.
Author: Shan, Tao|Ma, Qingyong|Zhang, Dong|Guo, Kun|Liu, Han|Wang, Fengfei|Wu, Erxi
PMID: 21570961
Journal: Anticancer Res. 2011 May;31(5):1549-58.
Title: Anticancer effect of dihydroartemisinin (DHA) in a pancreatic tumor model evaluated by conventional methods and optical imaging.
Author: Aung, Winn|Sogawa, Chizuru|Furukawa, Takako|Saga, Tsuneo
PMID: 21617209
Journal: Br J Surg. 2011 Aug;98(8):1041-55.
Title: Systematic review of immunohistochemical biomarkers to identify prognostic subgroups of patients with pancreatic cancer.
Author: Ansari, D|Rosendahl, A|Elebro, J|Andersson, R
PMID: 21644238
Journal: J Exp Clin Cancer Res. 2011 Jun 29;30:66.
Title: Oxymatrine induces human pancreatic cancer PANC-1 cells apoptosis via regulating expression of Bcl-2 and IAP families, and releasing of cytochrome c.
Author: Ling, Qi|Xu, Xiao|Wei, Xuyong|Wang, Weibing|Zhou, Bin|Wang, Bei|Zheng, Shusen
PMID: 21714853
Journal: PLoS One. 2011;6(6):e21573.
Title: Honokiol arrests cell cycle, induces apoptosis, and potentiates the cytotoxic effect of gemcitabine in human pancreatic cancer cells.
Author: Arora, Sumit|Bhardwaj, Arun|Srivastava, Sanjeev K|Singh, Seema|McClellan, Steven|Wang, Bin|Singh, Ajay P
PMID: 21720559
Journal: Br J Cancer. 2011 Aug 9;105(4):565-74.
Title: Functional and prognostic relevance of the homeobox protein MSX2 in malignant melanoma.
Author: Gremel, G|Ryan, D|Rafferty, M|Lanigan, F|Hegarty, S|Lavelle, M|Murphy, I|Unwin, L|Joyce, C|Faller, W|McDermott, E W|Sheahan, K|Ponten, F|Gallagher, W M
PMID: 21730974
Journal: Cancers (Basel). 2011 Jun 1;3(2):1527-49.
Title: Small molecule inhibitors of bcl-2 family proteins for pancreatic cancer therapy.
Author: Masood, Ashiq|Azmi, Asfar S|Mohammad, Ramzi M
PMID: 21760983
Journal: Int J Oncol. 2011 Dec;39(6):1381-90.
Title: Antitumor and apoptosis-promoting properties of emodin, an anthraquinone derivative from Rheum officinale Baill, against pancreatic cancer in mice via inhibition of Akt activation.
Author: Wei, Wei-Tian|Chen, Hui|Ni, Zhong-Lin|Liu, Hai-Bin|Tong, Hong-Fei|Fan, Ling|Liu, An|Qiu, Mai-Xuan|Liu, Dian-Lei|Guo, Hong-Chun|Wang, Zhao-Hong|Lin, Sheng-Zhang
PMID: 21805032
Journal: Arch Immunol Ther Exp (Warsz). 2011 Oct;59(5):385-97.
Title: Apoptosis in lymphocytes of pancreatic cancer patients: influence of preoperative enteral immunonutrition and extensive surgery.
Author: Slotwinski, Robert|Olszewski, Waldemar|Slodkowski, Maciej|Lech, Gustaw|Zaleska, Marzanna|Kedziora, Sylwia|Wluka, Anna|Domaszewska, Anna|Slotwinska, Sylwia|Krasnodebski, Wojciech|Wojcik, Zdzislaw
PMID: 21818634
Journal: Mol Cancer. 2011 Aug 31;10:106.
Title: Mesothelin confers pancreatic cancer cell resistance to TNF-alpha-induced apoptosis through Akt/PI3K/NF-kappaB activation and IL-6/Mcl-1 overexpression.
Author: Bharadwaj, Uddalak|Marin-Muller, Christian|Li, Min|Chen, Changyi|Yao, Qizhi
PMID: 21880146
Journal: Am J Transl Res. 2011 Aug 15;3(4):374-82. Epub 2011 Jul 26.
Title: Network modeling of CDF treated pancreatic cancer cells reveals a novel c-myc-p73 dependent apoptotic mechanism.
Author: Azmi, Asfar S|Ali, Shadan|Banerjee, Sanjeev|Bao, Bin|Maitah, Mai N|Padhye, Subhash|Philip, Philip A|Mohammad, Ramzi M|Sarkar, Fazlul H
PMID: 21904657
Journal: PLoS One. 2011;6(8):e24099.
Title: Targeting epigenetic regulation of miR-34a for treatment of pancreatic cancer by inhibition of pancreatic cancer stem cells.
Author: Nalls, Dara|Tang, Su-Ni|Rodova, Marianna|Srivastava, Rakesh K|Shankar, Sharmila
PMID: 21909380
Journal: Int J Nanomedicine. 2011;6:1929-35.
Title: Study of the enhanced anticancer efficacy of gambogic acid on Capan-1 pancreatic cancer cells when mediated via magnetic Fe3O4 nanoparticles.
Author: Wang, Cailian|Zhang, Haijun|Chen, Baoan|Yin, Haitao|Wang, Wenwen
PMID: 21931488
Journal: PLoS One. 2011;6(11):e26390.
Title: A peptide of SPARC interferes with the interaction between caspase8 and Bcl2 to resensitize chemoresistant tumors and enhance their regression in vivo.
Author: Rahman, Mahbuba|Chan, Annie P K|Tang, Michelle|Tai, Isabella T
PMID: 22069448
Journal: PLoS One. 2011;6(11):e27306.
Title: Hedgehog signaling antagonist GDC-0449 (Vismodegib) inhibits pancreatic cancer stem cell characteristics: molecular mechanisms.
Author: Singh, Brahma N|Fu, Junsheng|Srivastava, Rakesh K|Shankar, Sharmila
PMID: 22087285
Journal: Mol Cancer. 2011 Nov 26;10:146.
Title: beta2-adrenoceptor blockage induces G1/S phase arrest and apoptosis in pancreatic cancer cells via Ras/Akt/NFkappaB pathway.
Author: Zhang, Dong|Ma, Qingyong|Wang, Zheng|Zhang, Min|Guo, Kun|Wang, Fengfei|Wu, Erxi
PMID: 22118662
Journal: PLoS One. 2011;6(11):e27729.
Title: Murine pancreatic adenocarcinoma dampens SHIP-1 expression and alters MDSC homeostasis and function.
Author: Pilon-Thomas, Shari|Nelson, Nadine|Vohra, Nasreen|Jerald, Maya|Pendleton, Laura|Szekeres, Karoly|Ghansah, Tomar
PMID: 22132131
Journal: J Carcinog. 2011;10:24.
Title: Cyclin D1 inhibits whereas c-Myc enhances the cytotoxicity of cisplatin in mouse pancreatic cancer cells via regulation of several members of the NF-kappaB and Bcl-2 families.
Author: El-Kady, Ayman|Sun, Yuan|Li, Ying-Xia|Liao, D Joshua
PMID: 22190866
Journal: Pancreatology. 2011;11(6):601-9.
Title: Resveratrol inhibits proliferation and induces apoptosis through the hedgehog signaling pathway in pancreatic cancer cell.
Author: Mo, Wenhui|Xu, Xuanfu|Xu, Ling|Wang, Feng|Ke, Aiwu|Wang, Xingpeng|Guo, Chuanyong
PMID: 22301921
Journal: Curr Pharm Biotechnol. 2012 Sep;13(11):2235-47.
Title: The therapeutic potential of RNA interference: novel approaches for cancer treatment.
Author: Okamoto, Kinya|Murawaki, Yoshikazu
PMID: 21605072
Journal: Int J Cancer. 2012 Jul 1;131(1):30-40.
Title: Inhibition of sonic hedgehog pathway and pluripotency maintaining factors regulate human pancreatic cancer stem cell characteristics.
Author: Tang, Su-Ni|Fu, Junsheng|Nall, Dara|Rodova, Mariana|Shankar, Sharmila|Srivastava, Rakesh K
PMID: 21796625
Journal: Int J Cancer. 2012 Aug 1;131(3):E292-303.
Title: Zyflamend suppresses growth and sensitizes human pancreatic tumors to gemcitabine in an orthotopic mouse model through modulation of multiple targets.
Author: Kunnumakkara, Ajaikumar B|Sung, Bokyung|Ravindran, Jayaraj|Diagaradjane, Parmeswaran|Deorukhkar, Amit|Dey, Sanjit|Koca, Cemile|Tong, Zhimin|Gelovani, Juri G|Guha, Sushovan|Krishnan, Sunil|Aggarwal, Bharat B
PMID: 21935918
Journal: Cancer Lett. 2012 Mar 28;316(2):178-86.
Title: ShRNA silencing glycogen synthase kinase-3 beta inhibits tumor growth and angiogenesis in pancreatic cancer.
Author: Zhou, Wei|Wang, Li|Gou, Shan-Miao|Wang, Tong-Ling|Zhang, Meng|Liu, Tao|Wang, Chun-You
PMID: 22100174
Journal: Mol Med Rep. 2012 Mar;5(3):783-7.
Title: Matrine inhibits proliferation and induces apoptosis of the androgenindependent prostate cancer cell line PC-3.
Author: Zhang, Peng|Wang, Ziming|Chong, Tie|Ji, Zongzheng
PMID: 22159447
Journal: Int J Oncol. 2012 Apr;40(4):1049-57.
Title: Emodin reverses gemcitabine resistance in pancreatic cancer cells via the mitochondrial apoptosis pathway in vitro.
Author: Liu, Dian-Lei|Bu, Heqi|Li, Hong|Chen, Hui|Guo, Hong-Chun|Wang, Zhao-Hong|Tong, Hong-Fei|Ni, Zhong-Lin|Liu, Hai-Bin|Lin, Sheng-Zhang
PMID: 22159556
Journal: Tumour Biol. 2012 Jun;33(3):757-65.
Title: The dual PI3K/mTOR inhibitor NVP-BGT226 induces cell cycle arrest and regulates Survivin gene expression in human pancreatic cancer cell lines.
Author: Glienke, Wolfgang|Maute, Luise|Wicht, Johannes|Bergmann, Lothar
PMID: 22170433
Journal: Int J Mol Med. 2012 Apr;29(4):607-12.
Title: Antiproliferative effect of alpinetin in BxPC-3 pancreatic cancer cells.
Author: Du, Jian|Tang, Bo|Wang, Jingwen|Sui, Hongtao|Jin, Xueli|Wang, Liming|Wang, Zhongyu
PMID: 22246103
Journal: J Cancer Res Clin Oncol. 2012 May;138(5):785-97.
Title: Escin augments the efficacy of gemcitabine through down-regulation of nuclear factor-kappaB and nuclear factor-kappaB-regulated gene products in pancreatic cancer both in vitro and in vivo.
Author: Wang, Yong-Wei|Wang, Shuang-Jia|Zhou, Yi-Nan|Pan, Shang-Ha|Sun, Bei
PMID: 22270965
Journal: Anticancer Drugs. 2012 Jul;23(6):614-26.
Title: Noxa/Mcl-1 balance influences the effect of the proteasome inhibitor MG-132 in combination with anticancer agents in pancreatic cancer cell lines.
Author: Naumann, Katrin|Schmich, Kathrin|Jaeger, Christoph|Kratz, Felix|Merfort, Irmgard
PMID: 22314265
Journal: PLoS One. 2012;7(2):e32068.
Title: MicroRNAs targeting oncogenes are down-regulated in pancreatic malignant transformation from benign tumors.
Author: Jiao, Long R|Frampton, Adam E|Jacob, Jimmy|Pellegrino, Loredana|Krell, Jonathan|Giamas, Georgios|Tsim, Nicole|Vlavianos, Panagiotis|Cohen, Patrizia|Ahmad, Raida|Keller, Andreas|Habib, Nagy A|Stebbing, Justin|Castellano, Leandro
PMID: 22384141
Journal: Pancreatology. 2012 Mar-Apr;12(2):91-9.
Title: miR-15b and miR-16 induce the apoptosis of rat activated pancreatic stellate cells by targeting Bcl-2 in vitro.
Author: Shen, Jie|Wan, Rong|Hu, Guoyong|Yang, Lijuan|Xiong, Jie|Wang, Feng|Shen, Jiaqing|He, Shanshan|Guo, Xiaoyan|Ni, Jianbo|Guo, Chuanyong|Wang, Xingpeng
PMID: 22487517
Journal: Cancer Res. 2012 Jun 15;72(12):2949-56.
Title: In vivo imaging of drug-induced mitochondrial outer membrane permeabilization at single-cell resolution.
Author: Earley, Sarah|Vinegoni, Claudio|Dunham, Joshua|Gorbatov, Rostic|Feruglio, Paolo Fumene|Weissleder, Ralph
PMID: 22505651
Journal: PLoS One. 2012;7(4):e34582.
Title: RLIP76 regulates PI3K/Akt signaling and chemo-radiotherapy resistance in pancreatic cancer.
Author: Leake, Kathryn|Singhal, Jyotsana|Nagaprashantha, Lokesh Dalasanur|Awasthi, Sanjay|Singhal, Sharad S
PMID: 22509328
Journal: Pancreas. 2012 Oct;41(7):1048-57.
Title: Enhanced antitumor effect of combination therapy with gemcitabine and guggulsterone in pancreatic cancer.
Author: Ahn, Dong-Won|Seo, Jeong Kyun|Lee, Sang Hyub|Hwang, Jin-Hyeok|Lee, Jun Kyu|Ryu, Ji Kon|Kim, Yong-Tae|Yoon, Yong Bum
PMID: 22513291
Journal: Mol Cancer Ther. 2012 Jul;11(7):1598-608.
Title: CDK-4 inhibitor P276 sensitizes pancreatic cancer cells to gemcitabine-induced apoptosis.
Author: Subramaniam, Dharmalingam|Periyasamy, Giridharan|Ponnurangam, Sivapriya|Chakrabarti, Debarshi|Sugumar, Aravind|Padigaru, Muralidhara|Weir, Scott J|Balakrishnan, Arun|Sharma, Somesh|Anant, Shrikant
PMID: 22532602
Journal: Int J Biol Sci. 2012;8(4):533-47.
Title: Isoalantolactone induces reactive oxygen species mediated apoptosis in pancreatic carcinoma PANC-1 cells.
Author: Khan, Muhammad|Ding, Chuan|Rasul, Azhar|Yi, Fei|Li, Ting|Gao, Hongwen|Gao, Rong|Zhong, Lili|Zhang, Kun|Fang, Xuedong|Ma, Tonghui
PMID: 22532787
Journal: Int J Mol Med. 2012 Jul;30(1):93-9.
Title: Involvement of the mitochondrial pathway in bruceine D-induced apoptosis in Capan-2 human pancreatic adenocarcinoma cells.
Author: Liu, Ling|Lin, Zhi-Xiu|Leung, Po Sing|Chen, Li-Hua|Zhao, Ming|Liang, Juan
PMID: 22552257
Journal: Arch Med Res. 2012 Apr;43(3):252; author reply 253.
Title: Regarding article 'Bcl-2 upregulation induced by miR-21 via a direct interaction is associated with apoptosis and chemoresistance in MIA PaCa-2 pancreatic cancer cells'.
Author: Pan, Tian-Hong|Wu, Xiao-Yang
PMID: 22560983
Journal: Dig Dis Sci. 2012 Aug;57(8):2072-8.
Title: Induction of pancreatic cancer cell apoptosis and enhancement of gemcitabine sensitivity by RAP80 siRNA.
Author: Li, Ya|Gu, Wen-Jun|Liu, Hai-Lin
PMID: 22573342
Journal: Biochem Biophys Res Commun. 2012 Jun 15;422(4):596-601.
Title: Molecular basis for the interplay of apoptosis and proliferation mediated by Bcl-xL:Bim interactions in pancreatic cancer cells.
Author: Abrol, Ravinder|Edderkaoui, Mouad|Goddard, William A 3rd|Pandol, Stephen J
PMID: 22609401
Journal: Int J Nanomedicine. 2012;7:1793-804.
Title: Oridonin nanosuspension was more effective than free oridonin on G2/M cell cycle arrest and apoptosis in the human pancreatic cancer PANC-1 cell line.
Author: Qi, Xiaoli|Zhang, Dianrui|Xu, Xia|Feng, Feifei|Ren, Guijie|Chu, Qianqian|Zhang, Qiang|Tian, Keli
PMID: 22619528
Journal: PLoS One. 2012;7(5):e37509.
Title: Whole blood DNA aberrant methylation in pancreatic adenocarcinoma shows association with the course of the disease: a pilot study.
Author: Dauksa, Albertas|Gulbinas, Antanas|Barauskas, Giedrius|Pundzius, Juozas|Oldenburg, Johannes|El-Maarri, Osman
PMID: 22629410
Journal: Sichuan Da Xue Xue Bao Yi Xue Ban. 2012 Mar;43(2):156-60.
Title: [The expressions and correlation of bcl-2 and Beclin-1 in pancreatic cancer].
Author: Cao, Shuang-Shuang|Su, An-Ping|Du, Xiao-Jiong|Li, Ang|Hu, Wei-Minga|Zhang, Zhao-Da|Tian, Bo-Le|Lu, Hui-Min|Ke, Neng-Wen|He, Zhao-Peng
PMID: 22650021
Journal: Zhongguo Zhong Xi Yi Jie He Za Zhi. 2012 May;32(5):652-6.
Title: [Emodin combined gemcitabine inhibited the growth of pancreatic cancer in vitro and in vivo and its mechanisms study].
Author: Liu, An|Luo, Jiang|Zhang, Jian-Hong
PMID: 22679728
Journal: Pancreas. 2012 Nov;41(8):1247-54.
Title: Extracellular release of annexin II from pancreatic cancer cells and resistance to anticancer drug-induced apoptosis by supplementation of recombinant annexin II.
Author: Sato, Tetsuo|Kita, Kazuko|Sugaya, Shigeru|Suzuki, Toshikazu|Suzuki, Nobuo
PMID: 22750966
Journal: Oncol Rep. 2012 Oct;28(4):1339-45.
Title: Oleanolic acid potentiates the antitumor activity of 5-fluorouracil in pancreatic cancer cells.
Author: Wei, Jianteng|Liu, Haizhou|Liu, Ming|Wu, Ning|Zhao, Jin|Xiao, Lin|Han, Lijun|Chu, Edward|Lin, Xiukun
PMID: 22825128
Journal: Oncol Rep. 2012 Oct;28(4):1353-61.
Title: The molecular mechanism of luteolin-induced apoptosis is potentially related to inhibition of angiogenesis in human pancreatic carcinoma cells.
Author: Cai, Xueting|Lu, Wuguang|Ye, Tingmei|Lu, Min|Wang, Jianhua|Huo, Jiege|Qian, Shihui|Wang, Xiaoning|Cao, Peng
PMID: 22825765
Journal: PLoS One. 2012;7(7):e41102.
Title: Glycogen synthase kinase-3 inhibition sensitizes pancreatic cancer cells to TRAIL-induced apoptosis.
Author: Mamaghani, Shadi|Simpson, Craig D|Cao, Pinjiang M|Cheung, May|Chow, Sue|Bandarchi, Bizhan|Schimmer, Aaron D|Hedley, David W
PMID: 22829912
Journal: J Transl Med. 2012 Aug 8;10:161.
Title: Molecular evidence for increased antitumor activity of gemcitabine in combination with a cyclin-dependent kinase inhibitor, P276-00 in pancreatic cancers.
Author: Rathos, Maggie J|Joshi, Kavita|Khanwalkar, Harshal|Manohar, Sonal M|Joshi, Kalpana S
PMID: 22873289
Journal: PLoS One. 2012;7(8):e43064.
Title: Grape proanthocyanidin inhibit pancreatic cancer cell growth in vitro and in vivo through induction of apoptosis and by targeting the PI3K/Akt pathway.
Author: Prasad, Ram|Vaid, Mudit|Katiyar, Santosh K
PMID: 22905202
Journal: PLoS One. 2012;7(8):e43826.
Title: Pristimerin causes G1 arrest, induces apoptosis, and enhances the chemosensitivity to gemcitabine in pancreatic cancer cells.
Author: Wang, Yongwei|Zhou, Yinan|Zhou, Haoxin|Jia, Guang|Liu, Ji|Han, Bing|Cheng, Zhuoxin|Jiang, Hongchi|Pan, Shangha|Sun, Bei
PMID: 22952775
Journal: Neoplasia. 2012 Sep;14(9):778-87.
Title: Inhibition of pancreatic intraepithelial neoplasia progression to carcinoma by nitric oxide-releasing aspirin in p48(Cre/+)-LSL-Kras(G12D/+) mice.
Author: Rao, Chinthalapally V|Mohammed, Altaf|Janakiram, Naveena B|Li, Qian|Ritchie, Rebekah L|Lightfoot, Stan|Vibhudutta, Awasthi|Steele, Vernon E
PMID: 23019409
Journal: PLoS One. 2012;7(9):e46083.
Title: Sonic hedgehog signaling inhibition provides opportunities for targeted therapy by sulforaphane in regulating pancreatic cancer stem cell self-renewal.
Author: Rodova, Mariana|Fu, Junsheng|Watkins, Dara Nall|Srivastava, Rakesh K|Shankar, Sharmila
PMID: 23029396
Journal: J Exp Clin Cancer Res. 2012 Oct 3;31:84.
Title: Mesothelin regulates growth and apoptosis in pancreatic cancer cells through p53-dependent and -independent signal pathway.
Author: Zheng, Chunning|Jia, Wei|Tang, Yong|Zhao, HuiLiang|Jiang, Yingsheng|Sun, Shaochuan
PMID: 23034174
Journal: PLoS One. 2012;7(10):e46624.
Title: XZH-5 inhibits STAT3 phosphorylation and enhances the cytotoxicity of chemotherapeutic drugs in human breast and pancreatic cancer cells.
Author: Liu, Aiguo|Liu, Yan|Jin, Zhigang|Hu, Qun|Lin, Li|Jou, David|Yang, Jing|Xu, Zhenghu|Wang, Hong|Li, Chenglong|Lin, Jiayuh
PMID: 23056374
Journal: Anticancer Res. 2012 Oct;32(10):4385-94.
Title: Interference with ATF5 function enhances the sensitivity of human pancreatic cancer cells to paclitaxel-induced apoptosis.
Author: Hu, Ming|Wang, Bin|Qian, Dongmeng|Li, Ling|Zhang, Li|Song, Xuxia|Liu, David X
PMID: 23060563
Journal: Turk J Gastroenterol. 2012;23(5):427-37.
Title: Systemic treatment of neuroendocrine tumors with hepatic metastases.
Author: Demirkan, Binnaz H M|Eriksson, Barbro
PMID: 23161287
Journal: PLoS One. 2012;7(11):e47520.
Title: Pan-Bcl-2 inhibitor AT-101 enhances tumor cell killing by EGFR targeted T cells.
Author: Thakur, Archana|Lum, Lawrence G|Schalk, Dana|Azmi, Asfar|Banerjee, Sanjeev|Sarkar, Fazlul H|Mohommad, Ramzi
PMID: 23185240
Journal: BMC Cancer. 2012 Nov 30;12:564.
Title: Curcumin and synthetic analogs induce reactive oxygen species and decreases specificity protein (Sp) transcription factors by targeting microRNAs.
Author: Gandhy, Shruti U|Kim, Kyounghyun|Larsen, Lesley|Rosengren, Rhonda J|Safe, Stephen
PMID: 23194063
Journal: Mol Cell Biochem. 2013 Jan;373(1-2):217-27.
Title: Sulforaphane regulates self-renewal of pancreatic cancer stem cells through the modulation of Sonic hedgehog-GLI pathway.
Author: Li, Shih-Hui|Fu, Junsheng|Watkins, Dara Nall|Srivastava, Rakesh K|Shankar, Sharmila
PMID: 23129257
Journal: Anticancer Agents Med Chem. 2013 Jul 1;13(6):952-6.
Title: Cucurmosin kills human pancreatic cancer SW-1990 cells in vitro and in vivo.
Author: Xie, Jieming|Wang, Congfei|Yang, Aiqin|Zhang, Baoming|Yin, Qiang|Huang, Heguang|Chen, Minghuang
PMID: 23157594
Journal: Cancer Lett. 2013 Mar 1;330(1):22-32.
Title: GANT-61 inhibits pancreatic cancer stem cell growth in vitro and in NOD/SCID/IL2R gamma null mice xenograft.
Author: Fu, Junsheng|Rodova, Mariana|Roy, Sanjit K|Sharma, Jay|Singh, Karan P|Srivastava, Rakesh K|Shankar, Sharmila
PMID: 23200667
Journal: Biomed Pharmacother. 2013 Mar;67(2):133-9.
Title: Melatonin is involved in the apoptosis and necrosis of pancreatic cancer cell line SW-1990 via modulating of Bcl-2/Bax balance.
Author: Xu, Chunfang|Wu, Airong|Zhu, Hua|Fang, Huaying|Xu, Lele|Ye, Jianxin|Shen, Jiaqing
PMID: 23245210
Journal: Biomaterials. 2013 Mar;34(9):2265-76.
Title: Cationic microRNA-delivering nanovectors with bifunctional peptides for efficient treatment of PANC-1 xenograft model.
Author: Hu, Q L|Jiang, Q Y|Jin, X|Shen, J|Wang, K|Li, Y B|Xu, F J|Tang, G P|Li, Z H
PMID: 23298779
Journal: Oncol Rep. 2013 Apr;29(4):1659-65.
Title: Double inhibition of NF-kappaB and XIAP via RNAi enhances the sensitivity of pancreatic cancer cells to gemcitabine.
Author: Cao, Li-Ping|Song, Jian-Lin|Yi, Xiao-Ping|Li, Yi-Xiong
PMID: 23354694
Journal: Clin Transl Oncol. 2013 Sep;15(9):741-6.
Title: Resveratrol induces apoptosis of pancreatic cancers cells by inhibiting miR-21 regulation of BCL-2 expression.
Author: Liu, P|Liang, H|Xia, Q|Li, P|Kong, H|Lei, P|Wang, S|Tu, Z
PMID: 23359184
Journal: Pancreatology. 2013 Jan-Feb;13(1):72-8.
Title: Mechanism of action of salinomycin on growth and migration in pancreatic cancer cell lines.
Author: He, Lei|Wang, Fan|Dai, Wei-Qi|Wu, Dong|Lin, Chun-Lei|Wu, Shu-Mei|Cheng, Ping|Zhang, Yan|Shen, Miao|Wang, Chen-Feng|Lu, Jie|Zhou, Ying-Qun|Xu, Xuan-Fu|Xu, Ling|Guo, Chuan-Yong
PMID: 23395573
Journal: Apoptosis. 2013 Jul;18(7):861-9.
Title: CacyBP/SIP enhances multidrug resistance of pancreatic cancer cells by regulation of P-gp and Bcl-2.
Author: Chen, Xiong|Zheng, Peichan|Xue, Zengfu|Li, Jie|Wang, Wenwu|Chen, Xi|Xie, Fangwei|Yu, Zongyang|Ouyang, Xuenong
PMID: 23463283
Journal: PLoS One. 2013;8(3):e58055.
Title: Cytotoxic activity and apoptosis-inducing potential of di-spiropyrrolidino and di-spiropyrrolizidino oxindole andrographolide derivatives.
Author: Dey, Sumit Kumar|Bose, Dipayan|Hazra, Abhijit|Naskar, Subhendu|Nandy, Abhishek|Munda, Rudra Narayan|Das, Subhadip|Chatterjee, Nabanita|Mondal, Nirup Bikash|Banerjee, Sukdeb|Saha, Krishna Das
PMID: 23472133
Journal: Carcinogenesis. 2013 Jul;34(7):1585-92.
Title: Bitter melon juice activates cellular energy sensor AMP-activated protein kinase causing apoptotic death of human pancreatic carcinoma cells.
Author: Kaur, Manjinder|Deep, Gagan|Jain, Anil K|Raina, Komal|Agarwal, Chapla|Wempe, Michael F|Agarwal, Rajesh
PMID: 23475945
Journal: Mol Cancer Ther. 2013 Jun;12(6):853-64.
Title: Bcl-2/Bcl-xL inhibition increases the efficacy of MEK inhibition alone and in combination with PI3 kinase inhibition in lung and pancreatic tumor models.
Author: Tan, Nguyen|Wong, Maureen|Nannini, Michelle A|Hong, Rebecca|Lee, Leslie B|Price, Stephen|Williams, Karen|Savy, Pierre Pascal|Yue, Peng|Sampath, Deepak|Settleman, Jeffrey|Fairbrother, Wayne J|Belmont, Lisa D
PMID: 23475955
Journal: Cancer Lett. 2013 Aug 19;336(2):270-80.
Title: Holy Basil leaf extract decreases tumorigenicity and metastasis of aggressive human pancreatic cancer cells in vitro and in vivo: potential role in therapy.
Author: Shimizu, Tomohiro|Torres, Maria P|Chakraborty, Subhankar|Souchek, Joshua J|Rachagani, Satyanarayana|Kaur, Sukhwinder|Macha, Muzafar|Ganti, Apar K|Hauke, Ralph J|Batra, Surinder K
PMID: 23523869
Journal: Anticancer Drugs. 2013 Jul;24(6):566-76.
Title: Induction of pancreatic cancer cell apoptosis, invasion, migration, and enhancement of chemotherapy sensitivity of gemcitabine, 5-FU, and oxaliplatin by hnRNP A2/B1 siRNA.
Author: Gu, Wen-Jun|Liu, Hai-Lin
PMID: 23525071
Journal: World J Gastroenterol. 2013 Mar 14;19(10):1582-92.
Title: Effects of ginsenoside Rh2 on growth and migration of pancreatic cancer cells.
Author: Tang, Xi-Ping|Tang, Guo-Du|Fang, Chun-Yun|Liang, Zhi-Hai|Zhang, Lu-Yi
PMID: 23538603
Journal: PLoS One. 2013 Apr 16;8(4):e61977.
Title: Anti-pancreatic cancer deliverables from sea: first-hand evidence on the efficacy, molecular targets and mode of action for multifarious polyphenols from five different brown-algae.
Author: Aravindan, Sheeja|Delma, Caroline R|Thirugnanasambandan, Somasundaram S|Herman, Terence S|Aravindan, Natarajan
PMID: 23613993
Journal: Int J Mol Med. 2013 Jul;32(1):85-92.
Title: Sann-Joong-Kuey-Jian-Tang decreases the protein expression of Mcl1 and TCTP and increases that of TNF-alpha and Bax in BxPC3 pancreatic carcinoma cells.
Author: Chien, Su-Yu|Kuo, Shou-Jen|Chen, Dar-Ren|Su, Chin-Cheng
PMID: 23652631
Journal: PLoS One. 2013 May 10;8(5):e61015.
Title: Upregulation of miR-150* and miR-630 induces apoptosis in pancreatic cancer cells by targeting IGF-1R.
Author: Farhana, Lulu|Dawson, Marcia I|Murshed, Farhan|Das, Jayanta K|Rishi, Arun K|Fontana, Joseph A
PMID: 23675407
Journal: Cancer Lett. 2013 Sep 1;337(2):210-7.
Title: Ellagic acid inhibits human pancreatic cancer growth in Balb c nude mice.
Author: Zhao, Min|Tang, Su-Ni|Marsh, Justin L|Shankar, Sharmila|Srivastava, Rakesh K
PMID: 23684930
Journal: Biomaterials. 2013 Aug;34(26):6175-84.
Title: Suppression of pancreatic tumor growth by targeted arsenic delivery with anti-CD44v6 single chain antibody conjugated nanoparticles.
Author: Qian, Chenchen|Wang, Yong|Chen, Yinting|Zeng, Linjuan|Zhang, Qiubo|Shuai, Xintao|Huang, Kaihong
PMID: 23721794
Journal: Oncol Rep. 2013 Aug;30(2):801-8.
Title: SB365, Pulsatilla saponin D suppresses proliferation and induces apoptosis of pancreatic cancer cells.
Author: Son, Mi Kwon|Jung, Kyung Hee|Lee, Hee-Seung|Lee, Hyunseung|Kim, Soo Jung|Yan, Hong Hua|Ryu, Ye-Lim|Hong, Soon-Sun
PMID: 23733203
Journal: J Tradit Chin Med. 2013 Apr;33(2):205-10.
Title: Effect of Jinlong capsule on proliferation and apoptosis of human pancreatic cancer cells BxPC-3.
Author: Li, Yaoyuan|Hu, Jieqing|Huang, Hui|He, Yonghe
PMID: 23789218
Journal: Cancer Lett. 2013 Oct 10;339(2):185-94.
Title: Adenovirus vector-mediated Gli1 siRNA induces growth inhibition and apoptosis in human pancreatic cancer with Smo-dependent or Smo-independent Hh pathway activation in vitro and in vivo.
Author: Guo, Jiefang|Gao, Jun|Li, Zhaoshen|Gong, Yanfang|Man, Xiaohua|Jin, Jing|Wu, Hongyu
PMID: 23791879
Journal: Carcinogenesis. 2013 Dec;34(12):2870-9.
Title: Metformin inhibits pancreatic cancer cell and tumor growth and downregulates Sp transcription factors.
Author: Nair, Vijayalekshmi|Pathi, Satya|Jutooru, Indira|Sreevalsan, Sandeep|Basha, Riyaz|Abdelrahim, Maen|Samudio, Ismael|Safe, Stephen
PMID: 23803693
Journal: Histopathology. 2013 Sep;63(3):343-50.
Title: Immature squamous metaplasia (focal atypical epithelial hyperplasia) of the pancreatic duct-immunohistochemical distinction from intraductal carcinoma.
Author: Mochizuki, Kunio|Kondo, Tetsuo|Oishi, Naoki|Kawasaki, Tomonori|Nakazawa, Tadao|Yamane, Tetsu|Katoh, Ryohei
PMID: 23829443
Journal: Toxicol Lett. 2013 Sep 12;222(1):23-35.
Title: Andrographolide causes apoptosis via inactivation of STAT3 and Akt and potentiates antitumor activity of gemcitabine in pancreatic cancer.
Author: Bao, Guo-Qing|Shen, Bai-Yong|Pan, Chun-Peng|Zhang, Ya-Jing|Shi, Min-Min|Peng, Cheng-Hong
PMID: 23845849
Journal: Cancer Lett. 2013 Dec 1;341(2):166-77.
Title: Guggulsterone decreases proliferation and metastatic behavior of pancreatic cancer cells by modulating JAK/STAT and Src/FAK signaling.
Author: Macha, Muzafar A|Rachagani, Satyanarayana|Gupta, Suprit|Pai, Priya|Ponnusamy, Moorthy P|Batra, Surinder K|Jain, Maneesh
PMID: 23920124
Journal: Pharmacol Rep. 2013;65(3):682-8.
Title: Cucurmosin induces the apoptosis of human pancreatic cancer CFPAC-1 cells by inactivating the PDGFR-beta signalling pathway.
Author: Xie, Jieming|Wang, Congfei|Zhang, Baoming|Yang, Aiqin|Yin, Qiang|Huang, Heguang|Chen, Minghuang
PMID: 23950591
Journal: Biochim Biophys Acta. 2013 Dec;1833(12):2980-2987.
Title: Simultaneous knock-down of Bcl-xL and Mcl-1 induces apoptosis through Bax activation in pancreatic cancer cells.
Author: Takahashi, Hiroki|Chen, Monica C|Pham, Hung|Matsuo, Yoichi|Ishiguro, Hideyuki|Reber, Howard A|Takeyama, Hiromitsu|Hines, Oscar J|Eibl, Guido
PMID: 23954445
Journal: Oncol Rep. 2013 Dec;30(6):2765-70.
Title: Etoposide induces apoptosis via the mitochondrial- and caspase-dependent pathways and in non-cancer stem cells in Panc-1 pancreatic cancer cells.
Author: Zhang, She-Hong|Huang, Qian
PMID: 24100999
Journal: PLoS One. 2013 Oct 11;8(10):e77126.
Title: Digitoflavone inhibits IkappaBalpha kinase and enhances apoptosis induced by TNFalpha through downregulation of expression of nuclear factor kappaB-regulated gene products in human pancreatic cancer cells.
Author: Cai, Xueting|Lu, Wuguang|Yang, Yang|Yang, Jie|Ye, Juan|Gu, Zhenhua|Hu, Chunping|Wang, Xiaoning|Cao, Peng
PMID: 24146961
Journal: Mol Carcinog. 2014 Feb;53 Suppl 1:E53-61.
Title: Tolfenamic acid inhibits colon cancer cell and tumor growth and induces degradation of specificity protein (Sp) transcription factors.
Author: Pathi, Satya|Li, Xi|Safe, Stephen
PMID: 23670891
Journal: Tumour Biol. 2014 Jan;35(1):837-44.
Title: MiR-148a regulates the growth and apoptosis in pancreatic cancer by targeting CCKBR and Bcl-2.
Author: Zhang, Rui|Li, Min|Zang, Wenqiao|Chen, Xudong|Wang, Yuanyuan|Li, Ping|Du, Yuwen|Zhao, Guoqiang|Li, Li
PMID: 23975374
Journal: Nutr Cancer. 2014;66(4):747-55.
Title: Phenethyl isothiocyanate inhibits proliferation and induces apoptosis in pancreatic cancer cells in vitro and in a MIAPaca2 xenograft animal model.
Author: Stan, Silvia D|Singh, Shivendra V|Whitcomb, David C|Brand, Randall E
PMID: 24195616
Journal: Tumour Biol. 2014 Mar;35(3):2461-71.
Title: Bufalin exerts antitumor effects by inducing cell cycle arrest and triggering apoptosis in pancreatic cancer cells.
Author: Li, Meiying|Yu, Xuejun|Guo, Hui|Sun, Limei|Wang, Aijun|Liu, Qiji|Wang, Xiuwen|Li, Jisheng
PMID: 24218335
Journal: Curr Mol Med. 2014 Jan;14(1):125-40.
Title: Chemoprevention gene therapy (CGT) of pancreatic cancer using perillyl alcohol and a novel chimeric serotype cancer terminator virus.
Author: Sarkar, S|Azab, B|Quinn, B A|Shen, X|Dent, P|Klibanov, A L|Emdad, L|Das, S K|Sarkar, D|Fisher, P B
PMID: 24236457
Journal: Arch Med Res. 2014 Jan;45(1):15-20.
Title: Alteration of the intrinsic apoptosis pathway is involved in Notch-induced chemoresistance to gemcitabine in pancreatic cancer.
Author: Du, Xiao|Zhao, Yu-Pei|Zhang, Tai-Ping|Zhou, Li|Chen, Ge|Wang, Tian-Xiao|You, Lei|Shu, Hong
PMID: 24316112
Journal: J Immunother. 2014 Jan;37(1):8-15.
Title: Combining the antimesothelin immunotoxin SS1P with the BH3-mimetic ABT-737 induces cell death in SS1P-resistant pancreatic cancer cells.
Author: Hollevoet, Kevin|Antignani, Antonella|Fitzgerald, David J|Pastan, Ira
PMID: 24316551
Journal: Nutr Cancer. 2014;66(1):88-96.
Title: Gallic acid is an active component for the anticarcinogenic action of grape seed procyanidins in pancreatic cancer cells.
Author: Cedo, Lidia|Castell-Auvi, Anna|Pallares, Victor|Macia, Alba|Blay, Mayte|Ardevol, Anna|Motilva, Maria-Jose|Pinent, Montserrat
PMID: 24325191
Journal: Drug Des Devel Ther. 2013 Dec 18;8:39-47.
Title: (+)-Grandifloracin, an antiausterity agent, induces autophagic PANC-1 pancreatic cancer cell death.
Author: Ueda, Jun-ya|Athikomkulchai, Sirivan|Miyatake, Ryuta|Saiki, Ikuo|Esumi, Hiroyasu|Awale, Suresh
PMID: 24379655
Journal: Front Biosci (Landmark Ed). 2014 Jan 1;19:113-25.
Title: Embelin suppresses pancreatic cancer growth by modulating tumor immune microenvironment.
Author: Marsh, Justine L|Jackman, Chris P|Tang, Su-Ni|Shankar, Sharmila|Srivastava, Rakesh K
PMID: 24389175
Journal: World J Gastroenterol. 2014 Jan 7;20(1):193-203.
Title: Apoptotic pathway induced by diallyl trisulfide in pancreatic cancer cells.
Author: Ma, Hong-Bing|Huang, Shan|Yin, Xiao-Ran|Zhang, Yang|Di, Zheng-Li
PMID: 24415872
Journal: AAPS J. 2014 Mar;16(2):246-57.
Title: Antitumor activity of gemcitabine can be potentiated in pancreatic cancer through modulation of TLR4/NF-kappaB signaling by 6-shogaol.
Author: Zhou, Ling|Qi, Lianwen|Jiang, Lifeng|Zhou, Ping|Ma, Jiang|Xu, Xiaojun|Li, Ping
PMID: 24424498
Journal: Bioorg Med Chem. 2014 Feb 15;22(4):1496-505.
Title: A perylene derivative regulates HIF-1alpha and Stat3 signaling pathways.
Author: Chen, Han|Guan, Yongli|Yuan, Gu|Zhang, Qiang|Jing, Naijie
PMID: 24485121
Journal: Anticancer Res. 2014 Feb;34(2):701-6.
Title: Myricetin induces cell death of human colon cancer cells via BAX/BCL2-dependent pathway.
Author: Kim, Mi Eun|Ha, Tae Kwun|Yoon, Ju Hwa|Lee, Jun Sik
PMID: 24511002
Journal: Cancer Lett. 2014 Jun 28;348(1-2):20-8.
Title: Combination of AZD2281 (Olaparib) and GX15-070 (Obatoclax) results in synergistic antitumor activities in preclinical models of pancreatic cancer.
Author: Chen, Shaohua|Wang, Guan|Niu, Xiaojia|Zhao, Jianyun|Tan, Wenxi|Wang, Hebin|Zhao, Lijing|Ge, Yubin
PMID: 24534203
Journal: J Surg Res. 2014 May 15;188(2):387-95.
Title: Pulsatilla saponin A, an active molecule from Pulsatilla chinensis, induces cancer cell death and inhibits tumor growth in mouse xenograft models.
Author: Liu, Qiang|Chen, Weichang|Jiao, Yang|Hou, Jianquan|Wu, Qingyu|Liu, Yanli|Qi, Xiaofei
PMID: 24576780
Journal: Int J Oncol. 2014 May;44(5):1707-15.
Title: Pristimerin, a quinonemethide triterpenoid, induces apoptosis in pancreatic cancer cells through the inhibition of pro-survival Akt/NF-kappaB/mTOR signaling proteins and anti-apoptotic Bcl-2.
Author: Deeb, Dorrah|Gao, Xiaohua|Liu, Yong Bo|Pindolia, Kirit|Gautam, Subhash C
PMID: 24603988
Journal: Anat Rec (Hoboken). 2014 May;297(5):802-9.
Title: Berbamine enhances the antineoplastic activity of gemcitabine in pancreatic cancer cells by activating transforming growth factor-beta/Smad signaling.
Author: Jin, Xiaoli|Wu, Yulian
PMID: 24619961
Journal: Pancreas. 2014 Apr;43(3):470-7.
Title: Increased intratumoral interleukin 22 levels and frequencies of interleukin 22-producing CD4+ T cells correlate with pancreatic cancer progression.
Author: Xu, Xuejun|Tang, Yichen|Guo, Shixiang|Zhang, Yi|Tian, Yi|Ni, Bing|Wang, Huaizhi
PMID: 24622082
Journal: Zhonghua Zhong Liu Za Zhi. 2014 Jan;36(1):5-10.
Title: [Effects of dioscin on apoptosis in pancreatic cancer MiaPaCa-2 cells and its mechanism].
Author: Zhao, Xiao|Ren, He|Gao, Song|Hao, Jihui
PMID: 24685079
Journal: PLoS One. 2014 Apr 2;9(4):e92161.
Title: Embelin suppresses growth of human pancreatic cancer xenografts, and pancreatic cancer cells isolated from KrasG12D mice by inhibiting Akt and Sonic hedgehog pathways.
Author: Huang, Minzhao|Tang, Su-Ni|Upadhyay, Ghanshyam|Marsh, Justin L|Jackman, Christopher P|Shankar, Sharmila|Srivastava, Rakesh K
PMID: 24694877
Journal: Can J Physiol Pharmacol. 2014 Apr;92(4):324-9.
Title: Apoptosis induced by microwave radiation in pancreatic cancer JF305 cells.
Author: Zhu, Wenhe|Zhang, Wei|Wang, Huiyan|Xu, Junjie|Li, Yan|Lv, Shijie
PMID: 24708215
Journal: Curr Mol Med. 2014 May;14(4):555-63.
Title: Inhibition of autophagy strengthens celastrol-induced apoptosis in human pancreatic cancer in vitro and in vivo models.
Author: Zhao, X|Gao, S|Ren, H|Huang, H|Ji, W|Hao, J
PMID: 24730520
Journal: Int J Biochem Cell Biol. 2014 Aug;53:224-36.
Title: Use of herbal medicines and natural products: an alternative approach to overcoming the apoptotic resistance of pancreatic cancer.
Author: Li, Lin|Leung, Po Sing
PMID: 24875648
Journal: Biomed Res Int. 2014;2014:805926.
Title: Solanine induces mitochondria-mediated apoptosis in human pancreatic cancer cells.
Author: Sun, Hongwei|Lv, Chongqing|Yang, Longlong|Wang, Yingxiu|Zhang, Qingshun|Yu, Suhui|Kong, Hongru|Wang, Meng|Xie, Jianming|Zhang, Chunwu|Zhou, Mengtao
PMID: 24949471
Journal: J BUON. 2014 Apr-Jun;19(2):440-8.
Title: Exosome/staphylococcal enterotoxin B, an anti tumor compound against pancreatic cancer.
Author: Mahmoodzadeh Hosseini, Hamideh|Ali Imani Fooladi, Abbas|Soleimanirad, Jafar|Reza Nourani, Mohammad|Mahdavi, Mehdi
PMID: 24965404
Journal: Zhonghua Zhong Liu Za Zhi. 2014 May;36(5):335-40.
Title: [Mechanism of SPARC-enhanced chemosensitivity of pancreatic cancer cells to gemcitabine].
Author: Zhang, Jianxin|Jiang, Haihua|Mao, Zhengfa|Wang, Xuqing|Fan, Xin|Liu, Yu|Wang, Ying
PMID: 25030587
Journal: Cancer Lett. 2014 Oct 10;353(1):32-40.
Title: Rottlerin suppresses growth of human pancreatic tumors in nude mice, and pancreatic cancer cells isolated from Kras(G12D) mice.
Author: Huang, Minzhao|Tang, Su-Ni|Upadhyay, Ghanshyam|Marsh, Justin L|Jackman, Christopher P|Srivastava, Rakesh K|Shankar, Sharmila
PMID: 25050737
Journal: Cytokine. 2014 Dec;70(2):126-33.
Title: IL-35 promotes pancreas cancer growth through enhancement of proliferation and inhibition of apoptosis: evidence for a role as an autocrine growth factor.
Author: Nicholl, Michael B|Ledgewood, Chelsea L|Chen, Xuhui|Bai, Qian|Qin, Chenglu|Cook, Kathryn M|Herrick, Elizabeth J|Diaz-Arias, Alberto|Moore, Bradley J|Fang, Yujiang
PMID: 25073578
Journal: Int J Clin Exp Pathol. 2014 Jun 15;7(7):3827-35. eCollection 2014.
Title: PNMA1 promotes cell growth in human pancreatic ductal adenocarcinoma.
Author: Jiang, Shu-Heng|He, Ping|Ma, Ming-Ze|Wang, Yang|Li, Rong-Kun|Fang, Fang|Fu, Ying|Tian, Guang-Ang|Qin, Wen-Xin|Zhang, Zhi-Gang
PMID: 25120759
Journal: PLoS One. 2014 Sep 3;9(9):e106343.
Title: A miRNA signature of chemoresistant mesenchymal phenotype identifies novel molecular targets associated with advanced pancreatic cancer.
Author: Bera, Alakesh|VenkataSubbaRao, Kolaparthi|Manoharan, Muthu Saravanan|Hill, Ping|Freeman, James W
PMID: 25184537
Journal: Anticancer Res. 2014 Sep;34(9):4685-92.
Title: Genistein potentiates the antitumor effect of 5-Fluorouracil by inducing apoptosis and autophagy in human pancreatic cancer cells.
Author: Suzuki, Rei|Kang, Ya'an|Li, Xinqun|Roife, David|Zhang, Ran|Fleming, Jason B
PMID: 25202045
Journal: Oncol Lett. 2014 Oct;8(4):1859-1863.
Title: JWA gene regulates PANC-1 pancreatic cancer cell behaviors through MEK-ERK1/2 of the MAPK signaling pathway.
Author: Wu, Yuan-Yuan|Ma, Tie-Liang|Ge, Zhi-Jun|Lin, Jie|Ding, Wei-Liang|Feng, Jia-Ke|Zhou, Su-Jun|Chen, Guo-Chang|Tan, Yong-Fei|Cui, Guo-Xing
PMID: 25202426
Journal: Ultrasound Med Biol. 2014 Nov;40(11):2671-9.
Title: Sonodynamically induced anti-tumor effect of 5-aminolevulinic acid on pancreatic cancer cells.
Author: Li, Yan Jing|Huang, Peng|Jiang, Cai Ling|Jia, De Xin|Du, Xiao Xue|Zhou, Jian Hua|Han, Yu|Sui, Hong|Wei, Xiao Li|Liu, Lei|Yuan, Heng Heng|Zhang, Ting Ting|Zhang, Wen Jie|Xie, Rui|Lang, Xiao Hui|Wang, Li Ying|Liu, Tao|Bai, Yu Xian|Tian, Ye
PMID: 25220273
Journal: Mol Med Rep. 2014 Dec;10(6):3027-34.
Title: Enhancement of the effects of gemcitabine against pancreatic cancer by oridonin via the mitochondrial caspase-dependent signaling pathway.
Author: Liu, Dian-Lei|Bu, He-Qi|Jin, Hai-Min|Zhao, Jin-Feng|Li, Ye|Huang, Hai
PMID: 25242370
Journal: Cancer Lett. 2014 Dec 28;355(2):297-309.
Title: SKLB316, a novel small-molecule inhibitor of cell-cycle progression, induces G2/M phase arrest and apoptosis in vitro and inhibits tumor growth in vivo.
Author: Xia, Yong|Lei, Qian|Zhu, Yongxia|Ye, Tinghong|Wang, Ningyu|Li, Guobo|Shi, Xuanhong|Liu, Yantong|Shao, Bin|Yin, Tao|Zhao, Lifeng|Wu, Wenshuang|Song, Xuejiao|Xiong, Ying|Wei, Yuquan|Yu, Luoting
PMID: 25301449
Journal: Food Funct. 2014 Dec;5(12):3224-32.
Title: Anticancer effects on human pancreatic cancer cells of triterpenoids, polysaccharides and 1,3-beta-D-glucan derived from the fruiting body of Antrodia camphorata.
Author: Lee, Chu-I|Wu, Chih-Chung|Hsieh, Shu-Ling|Lee, Chun-Lin|Chang, Yueh-Ping|Chang, Chih-Chuan|Wang, Yi-Zhen|Wang, Jyh-Jye
PMID: 25317925
Journal: Oncol Rep. 2014 Dec;32(6):2789-94.
Title: Combination of chloroquine and GX15-070 (obatoclax) results in synergistic cytotoxicity against pancreatic cancer cells.
Author: Wang, Guan|Chen, Shaohua|Edwards, Holly|Cui, Xinming|Cui, Li|Ge, Yubin
PMID: 25333301
Journal: Int J Clin Exp Pathol. 2014 Oct 15;7(11):7536-44. eCollection 2014.
Title: Effect of DAPK1 gene on proliferation, migration, and invasion of carcinoma of pancreas BxPC-3 cell line.
Author: Qin, Yong|Ye, Guan-Xiong|Wu, Cheng-Jun|Wang, Shi|Pan, De-Biao|Jiang, Jin-Yan|Fu, Jing|Xu, Sheng-Qian
PMID: 25550789
Journal: World J Surg Oncol. 2014 Dec 30;12:404.
Title: Latexin inhibits the proliferation of CD133+ miapaca-2 pancreatic cancer stem-like cells.
Author: Xue, Zhan-Xiong|Zheng, Ji-Hang|Zheng, Zhi-Qiang|Cai, Jing-Li|Ye, Xiao-Hua|Wang, Cheng|Sun, Wei-Jian|Zhou, Xiang|Lu, Ming-Dong|Li, Pi-Hong|Cai, Zhen-Zhai
PMID: 25551472
Journal: Pancreas. 2015 Jan;44(1):144-51.
Title: Luteolin and Gemcitabine Protect Against Pancreatic Cancer in an Orthotopic Mouse Model.
Author: Johnson, Jodee L|Dia, Vermont P|Wallig, Matthew|Gonzalez de Mejia, Elvira
PMID: 25237909
Journal: Dig Dis Sci. 2015 Apr;60(4):1067-80.
Title: Thymoquinone Pretreatment Overcomes the Insensitivity and Potentiates the Antitumor Effect of Gemcitabine Through Abrogation of Notch1, PI3K/Akt/mTOR Regulated Signaling Pathways in Pancreatic Cancer.
Author: Mu, Gang-Gang|Zhang, Ling-Li|Li, Hong-Yan|Liao, Yan|Yu, Hong-Gang
PMID: 25344906
Journal: Mol Med Rep. 2015 Mar;11(3):2111-7.
Title: PKM2 gene regulates the behavior of pancreatic cancer cells via mitogen-activated protein kinase pathways.
Author: Feng, Jiake|Ma, Tieliang|Ge, Zhijun|Lin, Jie|Ding, Weiliang|Chen, Hong|Zhu, Wenjiao|Zhou, Sujun|Tan, Yongfei
PMID: 25411978
Journal: Biochem Biophys Res Commun. 2015 Jan 16;456(3):757-62.
Title: The MUC1 oncomucin regulates pancreatic cancer cell biological properties and chemoresistance. Implication of p42-44 MAPK, Akt, Bcl-2 and MMP13 pathways.
Author: Trehoux, Solange|Duchene, Belinda|Jonckheere, Nicolas|Van Seuningen, Isabelle
PMID: 25511698
Journal: Mol Pharmacol. 2015;87(3):543-60.
Title: Novel thiosemicarbazones regulate the signal transducer and activator of transcription 3 (STAT3) pathway: inhibition of constitutive and interleukin 6-induced activation by iron depletion.
Author: Lui, Goldie Y L|Kovacevic, Zaklina|V Menezes, Sharleen|Kalinowski, Danuta S|Merlot, Angelica M|Sahni, Sumit|Richardson, Des R
PMID: 25561562
Journal: Oncol Rep. 2015 Apr;33(4):1915-21.
Title: N,N'-di-(m-methylphenyi)-3,6-dimethyl-1,4-dihydro-1,2,4,5-tetrazine-1,4-dicarboam ide (ZGDHu-1) suppresses the proliferation of PANC-1 pancreatic cancer cells via apoptosis and G2/M cell cycle arrest.
Author: Chen, Su-Feng|Xia, Jun|Lv, Ya-Ping|Liu, Jin-Lin|Li, Wan-Xiang|Yu, Xi-Ping|Hu, Wei-Xiao|Zhou, Yong-Lie
PMID: 25683065
Journal: Apoptosis. 2015 Jun;20(6):843-57.
Title: Tenascin-C induces resistance to apoptosis in pancreatic cancer cell through activation of ERK/NF-kappaB pathway.
Author: Shi, Meiyan|He, Xiaodan|Wei, Wei|Wang, Juan|Zhang, Ti|Shen, Xiaohong
PMID: 25690319
Journal: Naunyn Schmiedebergs Arch Pharmacol. 2015 Jun;388(6):623-34.
Title: Longikaurin E induces apoptosis of pancreatic cancer cells via modulation of the p38 and PI3K/AKT pathways by ROS.
Author: Cheng, Hai-bo|Bo, Yun|Shen, Wei-xing|Ren, Xian-guo|Tan, Jia-ni|Jia, Zhi-rong|Xu, Chang-Liang
PMID: 25743573
Journal: Transl Oncol. 2015 Feb;8(1):47-54.
Title: Targeting mcl-1 for radiosensitization of pancreatic cancers.
Author: Wei, Dongping|Zhang, Qiang|Schreiber, Jason S|Parsels, Leslie A|Abulwerdi, Fardokht A|Kausar, Tasneem|Lawrence, Theodore S|Sun, Yi|Nikolovska-Coleska, Zaneta|Morgan, Meredith A
PMID: 25749177
Journal: J Immunother. 2015 Apr;38(3):116-26.
Title: Proapoptotic and antiapoptotic proteins of the Bcl-2 family regulate sensitivity of pancreatic cancer cells toward gemcitabine and T-cell-mediated cytotoxicity.
Author: Bauer, Christian|Hees, Claudia|Sterzik, Alexander|Bauernfeind, Franz|Mak'Anyengo, Rachel|Duewell, Peter|Lehr, Hans-Anton|Noessner, Elfriede|Wank, Rudolf|Trauzold, Anna|Endres, Stefan|Dauer, Marc|Schnurr, Max
PMID: 25751501
Journal: Biomed Pharmacother. 2015 Mar;70:151-7.
Title: miR-183 induces cell proliferation, migration, and invasion by regulating PDCD4 expression in the SW1990 pancreatic cancer cell line.
Author: Lu, Ying-Ying|Zheng, Jun-Yuan|Liu, Jie|Huang, Chun-Lan|Zhang, Wei|Zeng, Yue
PMID: 25776494
Journal: Oncoscience. 2014 Nov 11;2(1):15-30.
Title: Exosomal lipids induce human pancreatic tumoral MiaPaCa-2 cells resistance through the CXCR4-SDF-1alpha signaling axis.
Author: Beloribi-Djefaflia, Sadia|Siret, Carole|Lombardo, Dominique
PMID: 25821841
Journal: Int J Mol Med. 2015 Jun;35(6):1617-24.
Title: Combination of 12-O-tetradecanoylphorbol-13-acetate with diethyldithiocarbamate markedly inhibits pancreatic cancer cell growth in 3D culture and in immunodeficient mice.
Author: Huang, Huarong|Cao, Kajia|Malik, Saquib|Zhang, Qiuyan|Li, Dongli|Chang, Richard|Wang, Huaqian|Lin, Weiping|Van Doren, Jeremiah|Zhang, Kun|Du, Zhiyun|Zheng, Xi
PMID: 25847449
Journal: Pancreas. 2015 May;44(4):583-9.
Title: Primary and liver metastasis-derived cell lines from KrasG12D; Trp53R172H; Pdx-1 Cre animals undergo apoptosis in response to triptolide.
Author: Sangwan, Veena|Banerjee, Sulagna|Jensen, Kelsey M|Chen, Zhiyu|Chugh, Rohit|Dudeja, Vikas|Vickers, Selwyn M|Saluja, Ashok K
PMID: 25875797
Journal: World J Surg Oncol. 2015 Feb 21;13:66.
Title: pERK1/2 silencing sensitizes pancreatic cancer BXPC-3 cell to gemcitabine-induced apoptosis via regulating Bax and Bcl-2 expression.
Author: Wang, Min|Lu, Xingjiao|Dong, Xueguang|Hao, Fengyun|Liu, Zimin|Ni, Guangzhen|Chen, Dong
PMID: 25880226
Journal: World J Gastroenterol. 2015 Apr 21;21(15):4526-35.
Title: Growth inhibition and apoptosis induction by alternol in pancreatic carcinoma cells.
Author: Cong, Pei-Fang|Qu, Ying-Chun|Chen, Jie-Peng|Duan, Li-Li|Lin, Cheng-Jiang|Zhu, Xiao-Lin|Li-Ling, Jesse|Zhang, Mei-Xia
PMID: 25914461
Journal: Anticancer Agents Med Chem. 2015;15(10):1317-25.
Title: Promotion of Metastasis-associated Gene Expression in Survived PANC-1 Cells Following Trichostatin A Treatment.
Author: Chen, Zongjing|Yang, Yunxiu|Liu, Biao|Wang, Benquan|Sun, Meng|Zhang, Ling|Chen, Bicheng|You, Heyi|Zhou, Mengtao
PMID: 25991546
Journal: Cancer Res. 2015 Jun 1;75(11):2305-15.
Title: Pancreatic Cancer Combination Therapy Using a BH3 Mimetic and a Synthetic Tetracycline.
Author: Quinn, Bridget A|Dash, Rupesh|Sarkar, Siddik|Azab, Belal|Bhoopathi, Praveen|Das, Swadesh K|Emdad, Luni|Wei, Jun|Pellecchia, Maurizio|Sarkar, Devanand|Fisher, Paul B
PMID: 26032425
Journal: Nucleic Acid Ther. 2015 Aug;25(4):198-208.
Title: Effect of Polypurine Reverse Hoogsteen Hairpins on Relevant Cancer Target Genes in Different Human Cell Lines.
Author: Villalobos, Xenia|Rodriguez, Laura|Sole, Anna|Lliberos, Carolina|Mencia, Nuria|Ciudad, Carlos J|Noe, Veronique
PMID: 26042602
Journal: Oncotarget. 2015 Aug 28;6(25):21208-24.
Title: Metformin combined with aspirin significantly inhibit pancreatic cancer cell growth in vitro and in vivo by suppressing anti-apoptotic proteins Mcl-1 and Bcl-2.
Author: Yue, Wen|Zheng, Xi|Lin, Yong|Yang, Chung S|Xu, Qing|Carpizo, Darren|Huang, Huarong|DiPaola, Robert S|Tan, Xiang-Lin
PMID: 26056043
Journal: Sci Rep. 2015 Jun 16;5:11385.
Title: A G-quadruplex-binding compound showing anti-tumour activity in an in vivo model for pancreatic cancer.
Author: Ohnmacht, Stephan A|Marchetti, Chiara|Gunaratnam, Mekala|Besser, Rachael J|Haider, Shozeb M|Di Vita, Gloria|Lowe, Helen L|Mellinas-Gomez, Maria|Diocou, Seckou|Robson, Mathew|Sponer, Jiri|Islam, Barira|Pedley, R Barbara|Hartley, John A|Neidle, Stephen
PMID: 26077929
Journal: Mol Pharmacol. 2015 Sep;88(3):512-23.
Title: Targeted Inhibition of Phosphoinositide 3-Kinase/Mammalian Target of Rapamycin Sensitizes Pancreatic Cancer Cells to Doxorubicin without Exacerbating Cardiac Toxicity.
Author: Durrant, David E|Das, Anindita|Dyer, Samya|Tavallai, Seyedmehrad|Dent, Paul|Kukreja, Rakesh C
PMID: 26101222
Journal: Planta Med. 2015 Jul;81(10):838-46.
Title: Mechanism of Ascorbate-Induced Cell Death in Human Pancreatic Cancer Cells: Role of Bcl-2, Beclin 1 and Autophagy.
Author: Fukui, Masayuki|Yamabe, Noriko|Choi, Hye-Joung|Polireddy, Kishore|Chen, Qi|Zhu, Bao Ting
PMID: 26132849
Journal: Mol Med Rep. 2015 Oct;12(4):5415-22.
Title: Curcumin induces apoptosis in pancreatic cancer cells through the induction of forkhead box O1 and inhibition of the PI3K/Akt pathway.
Author: Zhao, Zhiming|Li, Chenggang|Xi, Hao|Gao, Yuanxing|Xu, Dabin
PMID: 26166196
Journal: Pancreas. 2015 Aug;44(6):988-94.
Title: Malignant Solitary Fibrous Tumor of the Pancreas.
Author: Estrella, Jeannelyn S|Wang, Huamin|Bhosale, Priya R|Evans, Harry L|Abraham, Susan C
PMID: 26166470
Journal: World J Gastroenterol. 2015 Jul 21;21(27):8352-7.
Title: Apoptosis of human pancreatic carcinoma cell-1 cells induced by Yin Chen Hao Decoction.
Author: Zhou, Hai-Bo|Chen, Jing-Ming|Shao, Li-Ming|Chen, Zhi-Gang
PMID: 26217086
Journal: Br J Cancer. 2015 Aug 11;113(4):660-8.
Title: MicroRNA-345 induces apoptosis in pancreatic cancer cells through potentiation of caspase-dependent and -independent pathways.
Author: Srivastava, Sanjeev K|Bhardwaj, Arun|Arora, Sumit|Tyagi, Nikhil|Singh, Seema|Andrews, Joel|McClellan, Steve|Wang, Bin|Singh, Ajay P
PMID: 26247574
Journal: Oncotarget. 2015 Sep 29;6(29):26895-908.
Title: A novel small-molecule IAP antagonist, AZD5582, draws Mcl-1 down-regulation for induction of apoptosis through targeting of cIAP1 and XIAP in human pancreatic cancer.
Author: Moon, Jai-Hee|Shin, Jae-Sik|Hong, Seung-Woo|Jung, Soo-A|Hwang, Ih-Yeon|Kim, Jeong Hee|Choi, Eun Kyoung|Ha, Seung-Hee|Kim, Jin-Sun|Kim, Kyoung-Mok|Hong, Dae-Won|Kim, Daejin|Kim, Yeong Seok|Kim, Jeong Eun|Kim, Kyu-Pyo|Hong, Yong Sang|Choi, Eun Kyung|Lee, Ju
PMID: 26314849
Journal: Case Rep Pathol. 2015;2015:149606.
Title: Importance of NAB2-STAT6 Fusion in the Diagnosis of Pancreatic Solitary Fibrous Tumor with Hamartoma-Like Features: A Case Report and Review of the Literature.
Author: Tanaka, Kei|Kishimoto, Takashi|Ohtsuka, Masayuki|Nakatani, Yukio|Miyazaki, Masaru
PMID: 26425382
Journal: Oncotarget. 2015 Dec 8;6(39):41902-15.
Title: Bcl-xL inhibition by molecular-targeting drugs sensitizes human pancreatic cancer cells to TRAIL.
Author: Hari, Yoko|Harashima, Nanae|Tajima, Yoshitsugu|Harada, Mamoru
PMID: 26506422
Journal: Arch Med Sci. 2015 Oct 12;11(5):1074-80.
Title: FK506-binding protein 5 inhibits proliferation and stimulates apoptosis of glioma cells.
Author: Yang, Hui|Zhang, Qing-Xiu|Pei, Dong-Sheng|Xu, Feng|Li, Yong|Yu, Ru-Tong
PMID: 26528353
Journal: Int J Clin Exp Med. 2015 Aug 15;8(8):12476-86. eCollection 2015.
Title: Clusterin silencing sensitizes pancreatic cancer MIA-PaCa-2 cells to gmcitabine via regulation of NF-kB/Bcl-2 signaling.
Author: Xu, Miao|Chen, Xiumei|Han, Yanling|Ma, Chunqing|Ma, Lin|Li, Shirong
PMID: 26550158
Journal: Genet Mol Res. 2015 Dec 2;14(4):15587-96.
Title: Effects of gemcitabine on radiosensitization, apoptosis, and Bcl-2 and Bax protein expression in human pancreatic cancer xenografts in nude mice.
Author: Shen, Z T|Wu, X H|Wang, L|Li, B|Zhu, X X
PMID: 26634526
Journal: Int J Clin Exp Med. 2015 Oct 15;8(10):17684-93. eCollection 2015.
Title: Fentanyl inhibits cell viability in human pancreatic cancer cell line and tumor growth in pancreatic cancer cell-transplanted mice.
Author: Miao, Jianxia|Wang, Liangrong|Chen, Lei|Yang, Tao|Jin, Lida|Lin, Lina
PMID: 26770358
Journal: Gene. 2016 Jan 15;576(1 Pt 3):476-82.
Title: Ferulic acid decreases cell viability and colony formation while inhibiting migration of MIA PaCa-2 human pancreatic cancer cells in vitro.
Author: Fahrioglu, Umut|Dodurga, Yavuz|Elmas, Levent|Secme, Mucahit
PMID: 26516023
Journal: Cancer Prev Res (Phila). 2016 Mar;9(3):234-44.
Title: Piperlongumine Suppresses Growth and Sensitizes Pancreatic Tumors to Gemcitabine in a Xenograft Mouse Model by Modulating the NF-kappa B Pathway.
Author: Wang, Yongwei|Wu, Xiangsong|Zhou, Yinan|Jiang, Hongchi|Pan, Shangha|Sun, Bei
PMID: 26667450
Journal: Tumour Biol. 2016 Jun;37(6):7345-55.
Title: Hyperoside induces apoptosis and inhibits growth in pancreatic cancer via Bcl-2 family and NF-kappaB signaling pathway both in vitro and in vivo.
Author: Li, Yilong|Wang, Yongwei|Li, Le|Kong, Rui|Pan, Shangha|Ji, Liang|Liu, Huan|Chen, Hua|Sun, Bei
PMID: 26676634
Journal: Mol Med Rep. 2016 Feb;13(2):1434-40.
Title: Reduced proliferation and increased apoptosis of the SGC7901 gastric cancer cell line on exposure to GDC0449.
Author: Wu, Chuanqing|Cheng, Ji|Hu, Shaobo|Deng, Rui|Muangu, Yamba Willy|Shi, Liang|Wu, Ke|Zhang, Peng|Chang, Weilong|Wang, Guobin|Tao, Kaixiong
PMID: 26676867
Journal: Oncotarget. 2016 Jan 26;7(4):4226-40.
Title: Overexpressed EDIL3 predicts poor prognosis and promotes anchorage-independent tumor growth in human pancreatic cancer.
Author: Jiang, Shu-Heng|Wang, Yang|Yang, Jian-Yu|Li, Jun|Feng, Ming-Xuan|Wang, Ya-Hui|Yang, Xiao-Mei|He, Ping|Tian, Guang-Ang|Zhang, Xiao-Xin|Li, Qing|Cao, Xiao-Yan|Huo, Yan-Miao|Yang, Min-Wei|Fu, Xue-Liang|Li, Jiao|Liu, De-Jun|Dai, Miao|Wen, Shan-Yun|Gu, Jian-Re
PMID: 26735172
Journal: Cancer Biother Radiopharm. 2016 Feb;31(1):7-13.
Title: Tectonic 1 Is a Key Regulator of Cell Proliferation in Pancreatic Cancer.
Author: Zhao, Shiyong|Chen, Xuedong|Wan, Ming|Jiang, Xingming|Li, Chunlong|Cui, Yunfu|Kang, Pengcheng
PMID: 26844847
Journal: Pancreatology. 2016 May-Jun;16(3):411-5.
Title: Molecular alterations in sporadic pancreatic neuroendocrine microadenomas.
Author: Hadano, Atsuko|Hirabayashi, Kenichi|Yamada, Misuzu|Kawanishi, Aya|Takanashi, Yumi|Kawaguchi, Yoshiaki|Nakagohri, Toshio|Nakamura, Naoya|Mine, Tetsuya
PMID: 26905832
Journal: Biomed Pharmacother. 2016 Apr;79:188-93.
Title: Long noncoding RNA HULC predicts poor clinical outcome and represents pro-oncogenic activity in diffuse large B-cell lymphoma.
Author: Peng, Wei|Wu, Jianzhong|Feng, Jifeng
PMID: 27044827
Journal: J Asian Nat Prod Res. 2016 Sep;18(9):837-47.
Title: Cardiac glycosides from the seeds of Thevetia peruviana and their pro-apoptotic activity toward cancer cells.
Author: Cheng, Huo-Yun|Tian, Dan-Mei|Tang, Jin-Shan|Shen, Wei-Zai|Yao, Xin-Sheng
PMID: 27086856
Journal: Oncol Rep. 2016 Jul;36(1):49-56.
Title: Regulation of cell apoptosis and proliferation in pancreatic cancer through PI3K/Akt pathway via Polo-like kinase 1.
Author: Mao, Yonghuan|Xi, Ling|Li, Quan|Cai, Zeling|Lai, Yimei|Zhang, Xinhua|Yu, Chunzhao
PMID: 27220401
Journal: PLoS One. 2016 May 25;11(5):e0155874.
Title: Small Molecule APY606 Displays Extensive Antitumor Activity in Pancreatic Cancer via Impairing Ras-MAPK Signaling.
Author: Guo, Na|Liu, Zuojia|Zhao, Wenjing|Wang, Erkang|Wang, Jin
PMID: 27223122
Journal: World J Gastroenterol. 2016 Jun 7;22(21):5012-22.
Title: CdSe/ZnS quantum dots induce photodynamic effects and cytotoxicity in pancreatic cancer cells.
Author: He, Si-Jia|Cao, Jia|Li, Yong-Sheng|Yang, Jia-Chun|Zhou, Min|Qu, Chun-Ying|Zhang, Yi|Shen, Feng|Chen, Ying|Li, Ming-Ming|Xu, Lei-Ming
PMID: 27275093
Journal: Oncol Rep. 2016 Aug;36(2):745-54.
Title: Inhibition of DACH1 activity by short hairpin RNA represses cell proliferation and tumor invasion in pancreatic cancer.
Author: Bu, Xiao-Na|Qiu, Chan|Wang, Chuan|Jiang, Zheng
PMID: 27278537
Journal: World J Gastrointest Surg. 2016 Jun 27;8(6):461-6.
Title: Solitary fibrous tumor of the pancreas: Case report and review of the literature.
Author: Paramythiotis, Daniel|Kofina, Konstantinia|Bangeas, Petros|Tsiompanou, Fani|Karayannopoulou, Georgia|Basdanis, George
PMID: 27358679
Journal: PLoS One. 2016 Jun 30;11(6):e0158617.
Title: A Platform for Rapid, Quantitative Assessment of Multiple Drug Combinations Simultaneously in Solid Tumors In Vivo.
Author: Dey, Joyoti|Kerwin, William S|Grenley, Marc O|Casalini, Joseph R|Tretyak, Ilona|Ditzler, Sally H|Thirstrup, Derek J|Frazier, Jason P|Pierce, Daniel W|Carleton, Michael|Klinghoffer, Richard A
PMID: 27359113
Journal: Free Radic Biol Med. 2016 Aug;97:342-350.
Title: Knockdown delta-5-desaturase promotes the formation of a novel free radical byproduct from COX-catalyzed omega-6 peroxidation to induce apoptosis and sensitize pancreatic cancer cells to chemotherapy drugs.
Author: Yang, Xiaoyu|Xu, Yi|Brooks, Amanda|Guo, Bin|Miskimins, Keith W|Qian, Steven Y
PMID: 27368132
Journal: Biochem Biophys Res Commun. 2016 Sep 9;478(1):293-299.
Title: The small-molecule IAP antagonist AT406 inhibits pancreatic cancer cells in vitro and in vivo.
Author: Jiang, Yongsheng|Meng, Qinghua|Chen, Bo|Shen, Haiyu|Yan, Bing|Sun, Baoyou
PMID: 27387230
Journal: Pak J Pharm Sci. 2016 Jul;29(4):1123-6.
Title: Radio sensitizing effect of aloe polysaccharide on pancreatic cancer bxpc-3 cells.
Author: Xu, Chunjin|Xu, Feng
PMID: 27393447
Journal: Tumour Biol. 2016 Oct;37(10):13121-13136.
Title: A novel colchicine-based microtubule inhibitor exhibits potent antitumor activity by inducing mitochondrial mediated apoptosis in MIA PaCa-2 pancreatic cancer cells.
Author: Kumar, Ashok|Singh, Baljinder|Mahajan, Girish|Sharma, Parduman R|Bharate, Sandip B|Mintoo, Mubashir J|Mondhe, Dilip M
PMID: 27449046
Journal: Oncol Rep. 2016 Sep;36(3):1517-25.
Title: Coix seed emulsion synergistically enhances the antitumor activity of gemcitabine in pancreatic cancer through abrogation of NF-kappaB signaling.
Author: Qian, Yafang|Yang, Bo|Xiong, Yang|Gu, Mancang
PMID: 27459907
Journal: Biomed Pharmacother. 2016 Oct;83:712-717.
Title: Long noncoding RNA CCDC26 as a potential predictor biomarker contributes to tumorigenesis in pancreatic cancer.
Author: Peng, Wei|Jiang, Airen
PMID: 27470572
Journal: Oncotarget. 2016 Sep 6;7(36):57783-57797.
Title: Role of SATB2 in human pancreatic cancer: Implications in transformation and a promising biomarker.
Author: Yu, Wei|Ma, Yiming|Shankar, Sharmila|Srivastava, Rakesh K
PMID: 27472393
Journal: Int J Cancer. 2016 Nov 1;139(9):2146.
Title: Retraction.
Author:
PMID: 27534921
Journal: Mol Cell Biol. 2016 Oct 13;36(21):2742-2754.
Title: Suppression of MicroRNA 200 Family Expression by Oncogenic KRAS Activation Promotes Cell Survival and Epithelial-Mesenchymal Transition in KRAS-Driven Cancer.
Author: Zhong, Xiaomin|Zheng, Lan|Shen, Jianfeng|Zhang, Dongmei|Xiong, Minmin|Zhang, Youyou|He, Xinhong|Tanyi, Janos L|Yang, Feng|Montone, Kathleen T|Chen, Xiaojun|Xu, Congjian|Xiang, Andy P|Huang, Qihong|Xu, Xiaowei|Zhang, Lin
PMID: 27550813
Journal: Biochem Biophys Res Commun. 2016 Oct 14;479(2):166-172.
Title: Short-chain C6 ceramide sensitizes AT406-induced anti-pancreatic cancer cell activity.
Author: Zhao, Xiaoguang|Sun, Baoyou|Zhang, Jingjing|Zhang, Ruishen|Zhang, Qing
PMID: 27562715
Journal: Oncol Rep. 2016 Nov;36(5):2861-2867.
Title: Melatonin induces cell apoptosis in Mia PaCa-2 cells via the suppression of nuclear factor-kappaB and activation of ERK and JNK: A novel therapeutic implication for pancreatic cancer.
Author: Li, Weimin|Wu, Jiansheng|Li, Zhiyin|Zhou, Zhibo|Zheng, Chao|Lin, Le|Tan, Binbin|Huang, Min|Fan, Mengdi
PMID: 27666165
Journal: J Cancer Res Ther. 2016 Oct;12(Supplement):1-4.
Title: Gemcitabine inhibits proliferation and induces apoptosis in human pancreatic cancer PANC-1 cells.
Author: Yong-Xian, Gui|Xiao-Huan, Li|Fan, Zhang|Guo-Fang, Tian
PMID: 27721241
Journal: PLoS One. 2016 Oct 19;11(10):e0162821.
Title: Dual Inhibition of Topoisomerase II and Tyrosine Kinases by the Novel Bis-Fluoroquinolone Chalcone-Like Derivative HMNE3 in Human Pancreatic Cancer Cells.
Author: Ma, Yong-Chao|Wang, Zhi-Xin|Jin, Shao-Ju|Zhang, Yan-Xin|Hu, Guo-Qiang|Cui, Dong-Tao|Wang, Jiang-Shuan|Wang, Min|Wang, Fu-Qing|Zhao, Zhi-Jun
PMID: 27760157
Journal: Mol Med Rep. 2016 Dec;14(6):5205-5210.
Title: PACE4 regulates apoptosis in human pancreatic cancer Panc1 cells via the mitochondrial signaling pathway.
Author: Tian, Xiao-Feng|Huang, Guo-Min|Zang, Hong-Liang|Cao, Hong
PMID: 27779720
Journal: Eur Rev Med Pharmacol Sci. 2016 Dec;20(23):4955-4964.
Title: Aconitine induces cell apoptosis in human pancreatic cancer via NF-kappaB signaling pathway.
Author: Ji, B-L|Xia, L-P|Zhou, F-X|Mao, G-Z|Xu, L-X
PMID: 27981537
Journal: Adv Prev Med. 2016;2016:1407840.
Title: Thymoquinone Promotes Pancreatic Cancer Cell Death and Reduction of Tumor Size through Combined Inhibition of Histone Deacetylation and Induction of Histone Acetylation.
Author: Relles, Daniel|Chipitsyna, Galina I|Gong, Qiaoke|Yeo, Charles J|Arafat, Hwyda A
PMID: 28105374
Journal: Sichuan Da Xue Xue Bao Yi Xue Ban. 2016 Sep;47(5):691-696.
Title: [MiR-183 Regulates Proliferation of SW1990 Pancreatic Cancer Cell Line by Targeting PDCD4].
Author: Lu, Ying-Ying|Zeng, Yue|Zheng, Jun-Yuan|Huang, Chun-Lan|Wang, Xing-Peng
PMID: 28598081
Journal: Oncol Res. 2017 Apr 14;25(4):559-569.
Title: Upregulation of MicroRNA-935 Promotes the Malignant Behaviors of Pancreatic Carcinoma PANC-1 Cells via Targeting Inositol Polyphosphate 4-Phosphatase Type I Gene (INPP4A).
Author: Wang, Cuiyue|Feng, Zhen|Jiang, Kaitong|Zuo, Xiuli
PMID: 27733216
Journal: Peptides. 2017 Feb;88:8-17.
Title: The anti-tumor effects of the recombinant toxin protein rLj-RGD3 from Lampetra japonica on pancreatic carcinoma Panc-1 cells in nude mice.
Author: Wang, Yue|Zheng, Yuanyuan|Tu, Zuoyu|Dai, Yongguo|Xu, Hong|Lv, Li|Wang, Jihong
PMID: 27988354
Journal: J Hematol Oncol. 2017 Jan 6;10(1):9.
Title: Phospho-Akt overexpression is prognostic and can be used to tailor the synergistic interaction of Akt inhibitors with gemcitabine in pancreatic cancer.
Author: Massihnia, Daniela|Avan, Amir|Funel, Niccola|Maftouh, Mina|van Krieken, Anne|Granchi, Carlotta|Raktoe, Rajiv|Boggi, Ugo|Aicher, Babette|Minutolo, Filippo|Russo, Antonio|Leon, Leticia G|Peters, Godefridus J|Giovannetti, Elisa
PMID: 28061880
Journal: Br J Pharmacol. 2017 Apr;174(7):553-568.
Title: Potent effects of dioscin against pancreatic cancer via miR-149-3P-mediated inhibition of the Akt1 signalling pathway.
Author: Si, Lingling|Xu, Lina|Yin, Lianhong|Qi, Yan|Han, Xu|Xu, Youwei|Zhao, Yanyan|Liu, Kexin|Peng, Jinyong
PMID: 28095588
Journal: Autophagy. 2017 Apr 3;13(4):703-714.
Title: MIR506 induces autophagy-related cell death in pancreatic cancer cells by targeting the STAT3 pathway.
Author: Sun, Longhao|Hu, Limei|Cogdell, David|Lu, Li|Gao, Chao|Tian, Weijun|Zhang, Zhixiang|Kang, Ya'an|Fleming, Jason B|Zhang, Wei
PMID: 28121485
Journal: Mol Med Rep. 2017 Mar;15(3):1195-1203.
Title: Moscatilin induces apoptosis of pancreatic cancer cells via reactive oxygen species and the JNK/SAPK pathway.
Author: Zhang, Lei|Fang, Yuan|Xu, Xue-Feng|Jin, Da-Yong
PMID: 28138710
Journal: Onco Targets Ther. 2017 Jan 18;10:417-428.
Title: Downregulation of DcR3 sensitizes hepatocellular carcinoma cells to TRAIL-induced apoptosis.
Author: Liang, Chaojie|Xu, Yingchen|Li, Guangming|Zhao, Tuanjie|Xia, Feng|Li, Guanqun|Zhang, Dongxin|Wu, Jixiang
PMID: 28176915
Journal: Int J Mol Med. 2017 Mar;39(3):569-578.
Title: TIEG1 deficiency confers enhanced myocardial protection in the infarcted heart by mediating the Pten/Akt signalling pathway.
Author: Cen, Mingqiu|Hu, Pengfei|Cai, Zhaobin|Fang, Tianfu|Zhang, Jiancheng|Lu, Ming
PMID: 28204828
Journal: Biomed Pharmacother. 2017 May;89:705-710.
Title: The effects of SAHA on radiosensitivity in pancreatic cancer cells by inducing apoptosis and targeting RAD51.
Author: Wu, Zhibing|Jing, Saisai|Li, Yanhong|Gao, Yabo|Yu, Shuhuan|Li, Zhitian|Zhao, Yanyan|Piao, Jigang|Ma, Shenglin|Chen, Xufeng
PMID: 28267674
Journal: Zhonghua Yi Xue Za Zhi. 2017 Mar 7;97(9):694-697.
Title: [Effects of high-intensity focused ultrasound on apoptosis-associated gene expression in xenografts with human pancreatic cancer].
Author: Hong, L L|Guo, Z|Xing, W G|Yu, H P|Liu, C F|Yang, X L|Wang, H L
PMID: 28297832
Journal: Biochem Biophys Res Commun. 2017 Jun 10;487(4):820-826.
Title: Brusatol inhibits growth and induces apoptosis in pancreatic cancer cells via JNK/p38 MAPK/NF-kappab/Stat3/Bcl-2 signaling pathway.
Author: Xiang, Yukai|Ye, Wen|Huang, Chaohao|Lou, Bin|Zhang, Jie|Yu, Dinglai|Huang, Xince|Chen, Bicheng|Zhou, Mengtao
PMID: 28455228
Journal: Cancer Treat Rev. 2017 May;56:28-35.
Title: Unraveling molecular pathways of poorly differentiated neuroendocrine carcinomas of the gastroenteropancreatic system: A systematic review.
Author: Girardi, Daniel M|Silva, Andrea C B|Rego, Juliana Florinda M|Coudry, Renata A|Riechelmann, Rachel P
PMID: 28456055
Journal: Am J Transl Res. 2017 Jun 15;9(6):2798-2806. eCollection 2017.
Title: The effects of miRNA-1180 on suppression of pancreatic cancer.
Author: Gu, Lei|Zhang, Jiaqiang|Shi, Minmin|Peng, Chenghong
PMID: 28670370
Journal: J Exp Clin Cancer Res. 2017 Jul 3;36(1):91.
Title: In vitro and in vivo cytotoxicity of troglitazone in pancreatic cancer.
Author: Fujita, Megumi|Hasegawa, Ai|Yamamori, Motohiro|Okamura, Noboru
PMID: 28673319
Journal: Tumour Biol. 2017 Jul;39(7):1010428317706917.
Title: Sporamin induces apoptosis and inhibits NF-kappaB activation in human pancreatic cancer cells.
Author: Qian, Cuijuan|Chen, Xiaoying|Qi, Yongxiao|Zhong, Sheng|Gao, Xinyan|Zheng, Wenjun|Mao, Zhixiang|Yao, Jun
PMID: 28714369
Journal: J Exp Clin Cancer Res. 2017 Aug 10;36(1):107.
Title: Gambogic acid sensitizes gemcitabine efficacy in pancreatic cancer by reducing the expression of ribonucleotide reductase subunit-M2 (RRM2).
Author: Xia, Guanggai|Wang, Hongcheng|Song, Ziliang|Meng, Qingcai|Huang, Xiuyan|Huang, Xinyu
PMID: 28797284
Journal: Biomed Pharmacother. 2017 Oct;94:1101-1110.
Title: Britannin induces apoptosis through AKT-FOXO1 pathway in human pancreatic cancer cells.
Author: Moeinifard, Marzieh|Hassan, Zuhair Mohammad|Fallahian, Faranak|Hamzeloo-Moghadam, Maryam|Taghikhani, Mohammad
PMID: 28821161
Journal: Cell Biochem Funct. 2017 Aug;35(6):315-326.
Title: Fractalkine/CX3CR1 induces apoptosis resistance and proliferation through the activation of the AKT/NF-kappaB cascade in pancreatic cancer cells.
Author: Wang, Hui|Cai, Jun|Du, Shaoxia|Guo, Zhongkui|Xin, Beibei|Wang, Juan|Wei, Wei|Shen, Xiaohong
PMID: 28845524
Journal: Biomed Pharmacother. 2017 Dec;96:650-658.
Title: The effects of novel chitosan-targeted gemcitabine nanomedicine mediating cisplatin on epithelial mesenchymal transition, invasion and metastasis of pancreatic cancer cells.
Author: Yu, Haibo|Song, Hongliang|Xiao, Jun|Chen, Haichuan|Jin, Xiaodan|Lin, Xizhou|Pan, Bujian|Ji, Wu
PMID: 29035831
Journal: Exp Ther Med. 2017 Oct;14(4):3720-3726.
Title: Silencing of TCTN1 inhibits proliferation, induces cell cycle arrest and apoptosis in human thyroid cancer.
Author: Xu, Peipei|Xia, Xiaotian|Yang, Zhili|Tian, Yuan|Di, Jianzhong|Guo, Minggao
PMID: 29042969
Journal: Evid Based Complement Alternat Med. 2017;2017:5787218.
Title: Curcumin Induces Autophagy, Apoptosis, and Cell Cycle Arrest in Human Pancreatic Cancer Cells.
Author: Zhu, Yaping|Bu, Shurui
PMID: 29081818
Journal: Oncotarget. 2017 Jul 19;8(43):74299-74311.
Title: Effect of p53 on pancreatic cancer-glucose tolerance abnormalities by regulating transglutaminase 2 in resistance to glucose metabolic stress.
Author: Su, Xiao|He, Xiangyi|Ben, Qiwen|Wang, Weiyi|Song, Huan|Ye, Qiao|Zang, Yi|Li, Weiguang|Chen, Ping|Yao, Weiyan|Yuan, Yaozong
PMID: 29088786
Journal: Oncotarget. 2017 Oct 9;8(61):103167-103181.
Title: Cucurbitacin B and SCH772984 exhibit synergistic anti-pancreatic cancer activities by suppressing EGFR, PI3K/Akt/mTOR, STAT3 and ERK signaling.
Author: Zhou, Jingkai|Zhao, Tiangang|Ma, Linfeng|Liang, Min|Guo, Ying-Jie|Zhao, Li-Mei
PMID: 29262554
Journal: Biochim Biophys Acta Mol Cell Res. 2018 Mar;1865(3):522-531.
Title: TRAIL induces apoptosis but not necroptosis in colorectal and pancreatic cancer cells preferentially via the TRAIL-R2/DR5 receptor.
Author: Nahacka, Zuzana|Svadlenka, Jan|Peterka, Martin|Ksandrova, Marie|Benesova, Simona|Neuzil, Jiri|Andera, Ladislav
PMID: 29278689
Journal: Oncol Rep. 2018 Apr;39(4):1892-1900.
Title: Tyrphostin B42 attenuates trichostatin A-mediated resistance in pancreatic cancer cells by antagonizing IL-6/JAK2/STAT3 signaling.
Author: Zhang, Xing|Lu, Hong|Hong, Weilong|Liu, Leping|Wang, Silu|Zhou, Mengtao|Chen, Bicheng|Bai, Yongheng
PMID: 29393444
Journal: Eur J Med Chem. 2018 Mar 10;147:66-76.
Title: Synthesis of novel Chlorin e6-curcumin conjugates as photosensitizers for photodynamic therapy against pancreatic carcinoma.
Author: Jalde, Shivakumar S|Chauhan, Anil Kumar|Lee, Ji Hoon|Chaturvedi, Pankaj Kumar|Park, Joon-Suk|Kim, Yong-Wan
PMID: 29421571
Journal: Phytomedicine. 2018 Jan 15;39:10-16.
Title: Genistein induced anticancer effects on pancreatic cancer cell lines involves mitochondrial apoptosis, G0/G1cell cycle arrest and regulation of STAT3 signalling pathway.
Author: Bi, Yi-Liang|Min, Min|Shen, Wei|Liu, Yan
PMID: 29433670
Journal: Cell Death Dis. 2018 Feb 12;9(2):210.
Title: Association of cytosolic sialidase Neu2 with plasma membrane enhances Fas-mediated apoptosis by impairing PI3K-Akt/mTOR-mediated pathway in pancreatic cancer cells.
Author: Nath, Shalini|Mandal, Chhabinath|Chatterjee, Uttara|Mandal, Chitra
PMID: 29434218
Journal: Oncotarget. 2017 Nov 20;9(4):4675-4697.
Title: Silver nanoparticles of different sizes induce a mixed type of programmed cell death in human pancreatic ductal adenocarcinoma.
Author: Zielinska, Ewelina|Zauszkiewicz-Pawlak, Agata|Wojcik, Michal|Inkielewicz-Stepniak, Iwona
PMID: 29435134
Journal: Oncogenesis. 2018 Feb 22;7(2):19.
Title: MUC13 contributes to rewiring of glucose metabolism in pancreatic cancer.
Author: Kumari, Sonam|Khan, Sheema|Gupta, Subash C|Kashyap, Vivek K|Yallapu, Murali M|Chauhan, Subhash C|Jaggi, Meena
PMID: 29467405
Journal: Int J Mol Med. 2018 May;41(5):2813-2831.
Title: Downregulated miR-23b-3p expression acts as a predictor of hepatocellular carcinoma progression: A study based on public data and RT-qPCR verification.
Author: He, Rong-Quan|Wu, Pei-Rong|Xiang, Xue-Lian|Yang, Xia|Liang, Hai-Wei|Qiu, Xiao-Hui|Yang, Li-Hua|Peng, Zhi-Gang|Chen, Gang
PMID: 29484429
Journal: J BUON. 2018 Jan-Feb;23(1):205-210.
Title: Sugiol (127horbar;hydroxyabieta-8,11,13-trien-7-one) targets human pancreatic carcinoma cells (Mia-PaCa2) by inducing apoptosis, G2/M cell cycle arrest, ROS production and inhibition of cancer cell migration.
Author: Hao, Chengfei|Zhang, Xibo|Zhang, Hongtao|Shang, Haitao|Bao, Jianheng|Wang, Haibo|Li, Zhonglian
PMID: 29552785
Journal: Mater Sci Eng C Mater Biol Appl. 2018 Aug 1;89:328-335.
Title: Antibody fragment-conjugated gemcitabine and paclitaxel-based liposome for effective therapeutic efficacy in pancreatic cancer.
Author: Yang, Wentao|Hu, Qian|Xu, Yanmei|Liu, Hailang|Zhong, Lin
PMID: 29752104
Journal: J Cell Mol Med. 2018 May 15.
Title: Chronic ethanol exposure of human pancreatic normal ductal epithelial cells induces cancer stem cell phenotype through SATB2.
Author: Yu, Wei|Ma, Yuming|Shankar, Sharmila|Srivastava, Rakesh K
PMID: 29761897
Journal: Food Funct. 2018 May 23;9(5):3018-3027.
Title: The dietary compound luteolin inhibits pancreatic cancer growth by targeting BCL-2.
Author: Li, Zhimei|Zhang, Yiyuan|Chen, Lixia|Li, Hua
PMID: 29770817
Journal: Cell Physiol Biochem. 2018;47(3):1007-1024.
Title: LINC01121 Inhibits Cell Apoptosis While Facilitating Proliferation, Migration, and Invasion Though Negative Regulation of the Camp/PKA Signaling Pathway via GLP1R.
Author: Qian, Yi-Gang|Ye, Zhou|Chen, Hai-Yong|Lv, Zhen|Zhang, Ai-Bin|Fan, Le|Zhou, Jie|Zheng, Shu-Sen|Wang, Wei-Lin
PMID: 29843149
Journal: Int J Oncol. 2018 Aug;53(2):672-684.
Title: WAVE3 promotes proliferation, migration and invasion via the AKT pathway in pancreatic cancer.
Author: Huang, Shaobin|Huang, Chensong|Chen, Wei|Liu, Yifeng|Yin, Xiaoyu|Lai, Jiaming|Liang, Lijian|Wang, Qian|Wang, Anxun|Zheng, Chaoxu
PMID: 29845225
Journal: Biomed Pharmacother. 2018 Sep;105:449-460.
Title: Eucalyptus microcorys leaf extract derived HPLC-fraction reduces the viability of MIA PaCa-2 cells by inducing apoptosis and arresting cell cycle.
Author: Bhuyan, Deep Jyoti|Vuong, Quan V|Bond, Danielle R|Chalmers, Anita C|Bowyer, Michael C|Scarlett, Christopher J
PMID: 29879629
Journal: Clin Exp Metastasis. 2018 Jul 9. pii: 10.1007/s10585-018-9919-5.
Title: The therapeutic targeting of the FGFR1/Src/NF-kappaB signaling axis inhibits pancreatic ductal adenocarcinoma stemness and oncogenicity.
Author: Lai, Shiue-Wei|Bamodu, Oluwaseun Adebayo|Tsai, Wen-Chiuan|Chang, Yi-Ming|Lee, Wei-Hwa|Yeh, Chi-Tai|Chao, Tsu-Yi
PMID: 29987671
Journal: Oxid Med Cell Longev. 2018 Jun 26;2018:2798070.
Title: Mitofusin2 Induces Cell Autophagy of Pancreatic Cancer through Inhibiting the PI3K/Akt/mTOR Signaling Pathway.
Author: Xue, Ran|Meng, Qinghua|Lu, Di|Liu, Xinjuan|Wang, Yanbin|Hao, Jianyu
PMID: 30046371
Journal: Mol Med Rep. 2018 Oct;18(4):3769-3779.
Title: EGFR may participate in immune evasion through regulation of B7H5 expression in nonsmall cell lung carcinoma.
Author: Dong, Zhaohui|Zhang, Lanying|Xu, Wei|Zhang, Gensheng
PMID: 30106102
Journal: Onco Targets Ther. 2018 Aug 1;11:4479-4490.
Title: Cordycepin induces apoptosis in human pancreatic cancer cells via the mitochondrial-mediated intrinsic pathway and suppresses tumor growth in vivo.
Author: Zhang, Yu|Zhang, Xiao Xi|Yuan, Rui Yan|Ren, Tai|Shao, Zi Yu|Wang, Hong Fei|Cai, Wei Long|Chen, Li Tian|Wang, Xu An|Wang, Ping
PMID: 30122940
Journal: Onco Targets Ther. 2018 Aug 6;11:4559-4572.
Title: Phytochemical analysis and antioxidant and anticancer activities of mastic gum resin from Pistacia atlantica subspecies kurdica.
Author: Rahman, Heshu Sulaiman
PMID: 30122948
Journal: Onco Targets Ther. 2018 Aug 10;11:4723-4732.
Title: Enhanced anticancer effects of low-dose curcumin with non-invasive pulsed electric field on PANC-1 cells.
Author: Lu, Chueh-Hsuan|Lin, Shu-Hui|Hsieh, Chih-Hsiung|Chen, Wei-Ting|Chao, Chih-Yu
PMID: 30127620
Journal: J Interferon Cytokine Res. 2018 Sep;38(9):413-422.
Title: Interferon Gamma Inhibits CXCL8-Induced Proliferation and Migration of Pancreatic Cancer BxPC-3 Cell Line via a RhoGDI2/Rac1/NF-kappaB Signaling Pathway.
Author: Zhang, Mingjie|Ding, Guoping|Zhou, Liangjing|Shen, Tao|Xu, Xiaodong|Zhao, Ting|Jia, Shengnan|Cao, LiPing
PMID: 30192158
Journal: Virchows Arch. 2018 Sep 29. pii: 10.1007/s00428-018-2455-5.
Title: Rab14 overexpression regulates gemcitabine sensitivity through regulation of Bcl-2 and mitochondrial function in pancreatic cancer.
Author: Ge, Jinnian|Ge, Chunlin
PMID: 30267303
Journal: Med Sci Monit. 2018 Oct 1;24:6975-6983.
Title: Mahanimbine Exerts Anticancer Effects on Human Pancreatic Cancer Cells by Triggering Cell Cycle Arrest, Apoptosis, and Modulation of AKT/Mammalian Target of Rapamycin (mTOR) and Signal Transducer and Activator of Transcription 3 (STAT3) Signalling Pathway
Author: Pei, Chenlin|He, Qun|Liang, Shuai|Gong, Xuejun
PMID: 30273298
Journal: Pharmacol Rep. 2018 May 17;70(6):1079-1088.
Title: Melatonin and its metabolite N1-acetyl-N2-formyl-5-methoxykynuramine (afmk) enhance chemosensitivity to gemcitabine in pancreatic carcinoma cells (PANC-1).
Author: Leja-Szpak, Anna|Nawrot-Porabka, Katarzyna|Goralska, Marta|Jastrzebska, Martyna|Link-Lenczowski, Pawel|Bonior, Joanna|Pierzchalski, Piotr|Jaworek, Jolanta
PMID: 30308458
Journal: Pancreatology. 2018 Aug 22. pii: S1424-3903(18)30658-6.
Title: Silencing of TRPM8 inhibits aggressive tumor phenotypes and enhances gemcitabine sensitivity in pancreatic cancer.
Author: Liu, JieFeng|Hu, GuoHuang|Gong, YuJing|Yu, QianLe|He, Bin|Li, WangHao|He, ZhiGuo|Hao, WenJie|He, ZiChao|Liu, YiPing
PMID: 30316690
Journal: Biochem Cell Biol. 2018 Oct 25.
Title: Silencing of Astrocyte elevated gene-1 (AEG-1) inhibits proliferation, migration and invasion, and promotes apoptosis in pancreatic cancer cells.
Author: Yang, Xing|Song, Shaowei
PMID: 30359541
Journal: Redox Biol. 2018 Oct 15;20:236-246.
Title: Dihomo-gamma-linolenic acid inhibits growth of xenograft tumors in mice bearing human pancreatic cancer cells (BxPC-3) transfected with delta-5-desaturase shRNA.
Author: Yang, Xiaoyu|Xu, Yi|Gao, Di|Yang, Liu|Qian, Steven Y
PMID: 30384258