Primary Site >> Colorectal Cancer

Gene >> AXL

Journal: Int J Cancer. 1995 Mar 16;60(6):791-7.
Title: Receptor tyrosine kinases expressed in metastatic colon cancer.
Author: Craven, R J|Xu, L H|Weiner, T M|Fridell, Y W|Dent, G A|Srivastava, S|Varnum, B|Liu, E T|Cance, W G
PMID: 7896447
Journal: Int J Cancer. 1999 Nov 26;83(5):579-84.
Title: Comparative tyrosine-kinase profiles in colorectal cancers: enhanced arg expression in carcinoma as compared with adenoma and normal mucosa.
Author: Chen, W S|Kung, H J|Yang, W K|Lin, W c
PMID: 10521789
Journal: J Exp Clin Cancer Res. 2004 Jun;23(2):263-8.
Title: Strong association of ARK5 with tumor invasion and metastasis.
Author: Kusakai, G|Suzuki, A|Ogura, T|Kaminishi, M|Esumi, H
PMID: 15354411
Journal: J Cell Physiol. 2005 Jul;204(1):36-44.
Title: Gas6 induces proliferation in prostate carcinoma cell lines expressing the Axl receptor.
Author: Sainaghi, Pier Paolo|Castello, Luigi|Bergamasco, Luca|Galletti, Margherita|Bellosta, Paola|Avanzi, Gian Carlo
PMID: 15605394
Journal: Mol Cancer Res. 2010 Feb;8(2):159-69.
Title: Myeloid zinc finger 1 induces migration, invasion, and in vivo metastasis through Axl gene expression in solid cancer.
Author: Mudduluru, Giridhar|Vajkoczy, Peter|Allgayer, Heike
PMID: 20145042
Journal: Oncogene. 2011 Jun 23;30(25):2888-99.
Title: Regulation of Axl receptor tyrosine kinase expression by miR-34a and miR-199a/b in solid cancer.
Author: Mudduluru, G|Ceppi, P|Kumarswamy, R|Scagliotti, G V|Papotti, M|Allgayer, H
PMID: 21317930
Journal: Mol Cell Proteomics. 2011 Aug;10(8):M111.010462.
Title: Genome-wide characterization of miR-34a induced changes in protein and mRNA expression by a combined pulsed SILAC and microarray analysis.
Author: Kaller, Markus|Liffers, Sven-Thorsten|Oeljeklaus, Silke|Kuhlmann, Katja|Roh, Simone|Hoffmann, Reinhard|Warscheid, Bettina|Hermeking, Heiko
PMID: 21566225
Journal: Acta Biochim Pol. 2012;59(4):467-74. Epub 2012 Nov 21.
Title: The role of microRNA in metastatic colorectal cancer and its significance in cancer prognosis and treatment.
Author: Tokarz, Paulina|Blasiak, Janusz
PMID: 23173124
Journal: PLoS One. 2013;8(1):e54211.
Title: TAZ expression as a prognostic indicator in colorectal cancer.
Author: Yuen, Hiu-Fung|McCrudden, Cian M|Huang, Yu-Han|Tham, Jill M|Zhang, Xiaoqian|Zeng, Qi|Zhang, Shu-Dong|Hong, WanJin
PMID: 23372686
Journal: Mol Cancer Ther. 2013 Sep;12(9):1749-62.
Title: S49076 is a novel kinase inhibitor of MET, AXL, and FGFR with strong preclinical activity alone and in association with bevacizumab.
Author: Burbridge, Mike F|Bossard, Celine J|Saunier, Carine|Fejes, Imre|Bruno, Alain|Leonce, Stephane|Ferry, Gilles|Da Violante, Georges|Bouzom, Francois|Cattan, Valerie|Jacquet-Bescond, Anne|Comoglio, Paolo M|Lockhart, Brian P|Boutin, Jean A|Cordi, Alex|Ortuno,
PMID: 23804704
Journal: Clin Cancer Res. 2013 Oct 1;19(19):5275-80.
Title: Molecular pathways: MERTK signaling in cancer.
Author: Cummings, Christopher T|Deryckere, Deborah|Earp, H Shelton|Graham, Douglas K
PMID: 23833304
Journal: J Clin Invest. 2013 Aug;123(8):3231-42.
Title: MerTK inhibition in tumor leukocytes decreases tumor growth and metastasis.
Author: Cook, Rebecca S|Jacobsen, Kristen M|Wofford, Anne M|DeRyckere, Deborah|Stanford, Jamie|Prieto, Anne L|Redente, Elizabeth|Sandahl, Melissa|Hunter, Debra M|Strunk, Karen E|Graham, Douglas K|Earp, H Shelton 3rd
PMID: 23867499
Journal: Proc Natl Acad Sci U S A. 2013 Aug 6;110(32):13091-6.
Title: Paradoxical role of the proto-oncogene Axl and Mer receptor tyrosine kinases in colon cancer.
Author: Bosurgi, Lidia|Bernink, Jochem H|Delgado Cuevas, Victor|Gagliani, Nicola|Joannas, Leonel|Schmid, Edward T|Booth, Carmen J|Ghosh, Sourav|Rothlin, Carla V
PMID: 23878224
Journal: Clin Cancer Res. 2014 Jan 1;20(1):164-75.
Title: AXL is a key regulator of inherent and chemotherapy-induced invasion and predicts a poor clinical outcome in early-stage colon cancer.
Author: Dunne, Philip D|McArt, Darragh G|Blayney, Jaine K|Kalimutho, Murugan|Greer, Samanda|Wang, Tingting|Srivastava, Supriya|Ong, Chee Wee|Arthur, Ken|Loughrey, Maurice|Redmond, Keara|Longley, Daniel B|Salto-Tellez, Manuel|Johnston, Patrick G|Van Schaeybroeck,
PMID: 24170546
Journal: Oncotarget. 2014 Oct 15;5(19):9199-213.
Title: Mutational analysis of genes coding for cell surface proteins in colorectal cancer cell lines reveal novel altered pathways, druggable mutations and mutated epitopes for targeted therapy.
Author: Donnard, Elisa|Asprino, Paula F|Correa, Bruna R|Bettoni, Fabiana|Koyama, Fernanda C|Navarro, Fabio C P|Perez, Rodrigo O|Mariadason, John|Sieber, Oliver M|Strausberg, Robert L|Simpson, Andrew J G|Jardim, Denis L F|Reis, Luiz Fernando L|Parmigiani, Raphael
PMID: 25193853
Journal: Clin Cancer Res. 2014 Feb 1;20(3):604-16.
Title: The disparate twins: a comparative study of CXCR4 and CXCR7 in SDF-1alpha-induced gene expression, invasion and chemosensitivity of colon cancer.
Author: Heckmann, Doreen|Maier, Patrick|Laufs, Stephanie|Li, Li|Sleeman, Jonathan P|Trunk, Marcus J|Leupold, Jorg H|Wenz, Frederik|Zeller, W Jens|Fruehauf, Stefan|Allgayer, Heike
PMID: 24255072
Journal: Oncotarget. 2015 Sep 15;6(27):23281-96.
Title: AXL is an oncotarget in human colorectal cancer.
Author: Martinelli, Erika|Martini, Giulia|Cardone, Claudia|Troiani, Teresa|Liguori, Giuseppina|Vitagliano, Donata|Napolitano, Stefania|Morgillo, Floriana|Rinaldi, Barbara|Melillo, Rosa Marina|Liotti, Federica|Nappi, Anna|Bianco, Roberto|Berrino, Liberato|Ciuffred
PMID: 25966280
Journal: Oncol Lett. 2016 Feb;11(2):1223-1229.
Title: Association between the expression levels of TAZ, AXL and CTGF and clinicopathological parameters in patients with colon cancer.
Author: Zhang, Shu-Dong|McCrudden, Cian M|Yuen, Hiu-Fung|Leung, Ka Lai|Hong, Wan-Jin|Kwok, Hang Fai
PMID: 26893723
Journal: Oncotarget. 2016 Aug 30;7(35):56355-56370.
Title: TAM receptors Tyro3 and Mer as novel targets in colorectal cancer.
Author: Schmitz, Robin|Valls, Aida Freire|Yerbes, Rosario|von Richter, Sophie|Kahlert, Christoph|Loges, Sonja|Weitz, Jurgen|Schneider, Martin|Ruiz de Almodovar, Carmen|Ulrich, Alexis|Schmidt, Thomas
PMID: 27486820
Journal: Cancer Lett. 2016 Nov 1;382(1):32-43.
Title: Broad RTK-targeted therapy overcomes molecular heterogeneity-driven resistance to cetuximab via vectored immunoprophylaxis in colorectal cancer.
Author: Hu, Shi|Dai, Haibin|Li, Tian|Tang, Ying|Fu, Wenyan|Yuan, Qingning|Wang, Feifei|Lv, Gaojian|Lv, Yuanyuan|Fan, Xiaoyan|Zhang, Sheng|Jin, Ruobing|Shen, Yafeng|Lin, Fangxing|Ye, Xuting|Ding, Min|Yang, Yongji|Lei, Changhai
PMID: 27569653
Journal: Cancer Res. 2017 May 15;77(10):2746-2758.
Title: miR-34a and miR-34b/c Suppress Intestinal Tumorigenesis.
Author: Jiang, Longchang|Hermeking, Heiko
PMID: 28363996
Journal: Sci Rep. 2017 Apr 4;7(1):641.
Title: Integrated analysis of gene expression and copy number identified potential cancer driver genes with amplification-dependent overexpression in 1,454 solid tumors.
Author: Ohshima, Keiichi|Hatakeyama, Keiichi|Nagashima, Takeshi|Watanabe, Yuko|Kanto, Kaori|Doi, Yuki|Ide, Tomomi|Shimoda, Yuji|Tanabe, Tomoe|Ohnami, Sumiko|Ohnami, Shumpei|Serizawa, Masakuni|Maruyama, Koji|Akiyama, Yasuto|Urakami, Kenichi|Kusuhara, Masatoshi|Moc
PMID: 28377632
Journal: World J Gastroenterol. 2017 May 21;23(19):3440-3448.
Title: Role of AXL in invasion and drug resistance of colon and breast cancer cells and its association with p53 alterations.
Author: Abdel-Rahman, Wael M|Al-Khayyal, Noura A|Nair, Vidhya A|Aravind, S R|Saber-Ayad, Maha
PMID: 28596680
Journal: PLoS One. 2017 Jul 20;12(7):e0179979.
Title: The receptor tyrosine kinase AXL promotes migration and invasion in colorectal cancer.
Author: Uribe, Diana J|Mandell, Edward K|Watson, Adam|Martinez, Jesse D|Leighton, Jonathan A|Ghosh, Sourav|Rothlin, Carla V
PMID: 28727830
Journal: JAMA Intern Med. 2017 Dec 1;177(12):1774-1780.
Title: Association of Warfarin Use With Lower Overall Cancer Incidence Among Patients Older Than 50 Years.
Author: Haaland, Gry S|Falk, Ragnhild S|Straume, Oddbjorn|Lorens, James B
PMID: 29114736
Journal: J Biol Chem. 2018 Jul 13;293(28):11166-11178.
Title: ATP-binding cassette member B5 (ABCB5) promotes tumor cell invasiveness in human colorectal cancer.
Author: Guo, Qin|Grimmig, Tanja|Gonzalez, Gabriel|Giobbie-Hurder, Anita|Berg, Gretchen|Carr, Nolan|Wilson, Brian J|Banerjee, Pallavi|Ma, Jie|Gold, Jason S|Nandi, Bisweswar|Huang, Qin|Waaga-Gasser, Ana Maria|Lian, Christine G|Murphy, George F|Frank, Markus H|Gasse
PMID: 29789423
Journal: Mol Cancer Ther. 2018 Jul 19. pii: 1535-7163.MCT-17-0131.
Title: Cabozantinib exhibits potent antitumor activity in colorectal cancer patient-derived tumor xenograft models via autophagy and signaling mechanisms.
Author: Scott, Aaron J|Arcaroli, John J|Bagby, Stacey M|Yahn, Rachel|Huber, Kendra M|Serkova, Natalie J|Nguyen, Anna|Kim, Jihye|Thorburn, Andrew|Vogel, Jon|Quackenbush, Kevin S|Capasso, Anna|Schreiber, Anna|Blatchford, Patrick|Klauck, Peter J|Pitts, Todd M|Eckhar
PMID: 30026382