Primary Site >> Colorectal Cancer
Gene >> AXL
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Ref: Receptor tyrosine kinases expressed in metastatic colon cancer. PMID: 7896447 |
Ref: Comparative tyrosine-kinase profiles in colorectal cancers: enhanced arg expression in carcinoma as compared with adenoma and normal mucosa. PMID: 10521789 |
Ref: Strong association of ARK5 with tumor invasion and metastasis. PMID: 15354411 |
Ref: Gas6 induces proliferation in prostate carcinoma cell lines expressing the Axl receptor. PMID: 15605394 |
Ref: Myeloid zinc finger 1 induces migration, invasion, and in vivo metastasis through Axl gene expression in solid cancer. PMID: 20145042 |
Ref: Regulation of Axl receptor tyrosine kinase expression by miR-34a and miR-199a/b in solid cancer. PMID: 21317930 Ref: Genome-wide characterization of miR-34a induced changes in protein and mRNA expression by a combined pulsed SILAC and microarray analysis. PMID: 21566225 |
Ref: The role of microRNA in metastatic colorectal cancer and its significance in cancer prognosis and treatment. PMID: 23173124 |
Ref: TAZ expression as a prognostic indicator in colorectal cancer. PMID: 23372686 Ref: S49076 is a novel kinase inhibitor of MET, AXL, and FGFR with strong preclinical activity alone and in association with bevacizumab. PMID: 23804704 Ref: Molecular pathways: MERTK signaling in cancer. PMID: 23833304 Ref: MerTK inhibition in tumor leukocytes decreases tumor growth and metastasis. PMID: 23867499 Ref: Paradoxical role of the proto-oncogene Axl and Mer receptor tyrosine kinases in colon cancer. PMID: 23878224 |
Ref: AXL is a key regulator of inherent and chemotherapy-induced invasion and predicts a poor clinical outcome in early-stage colon cancer. PMID: 24170546 Ref: The disparate twins: a comparative study of CXCR4 and CXCR7 in SDF-1alpha-induced gene expression, invasion and chemosensitivity of colon cancer. PMID: 24255072 Ref: Mutational analysis of genes coding for cell surface proteins in colorectal cancer cell lines reveal novel altered pathways, druggable mutations and mutated epitopes for targeted therapy. PMID: 25193853 |
Ref: AXL is an oncotarget in human colorectal cancer. PMID: 25966280 |
Ref: Association between the expression levels of TAZ, AXL and CTGF and clinicopathological parameters in patients with colon cancer. PMID: 26893723 Ref: TAM receptors Tyro3 and Mer as novel targets in colorectal cancer. PMID: 27486820 Ref: Broad RTK-targeted therapy overcomes molecular heterogeneity-driven resistance to cetuximab via vectored immunoprophylaxis in colorectal cancer. PMID: 27569653 |
Ref: miR-34a and miR-34b/c Suppress Intestinal Tumorigenesis. PMID: 28363996 Ref: Integrated analysis of gene expression and copy number identified potential cancer driver genes with amplification-dependent overexpression in 1,454 solid tumors. PMID: 28377632 Ref: Role of AXL in invasion and drug resistance of colon and breast cancer cells and its association with p53 alterations. PMID: 28596680 Ref: The receptor tyrosine kinase AXL promotes migration and invasion in colorectal cancer. PMID: 28727830 Ref: Association of Warfarin Use With Lower Overall Cancer Incidence Among Patients Older Than 50 Years. PMID: 29114736 |
Ref: ATP-binding cassette member B5 (ABCB5) promotes tumor cell invasiveness in human colorectal cancer. PMID: 29789423 Ref: Cabozantinib exhibits potent antitumor activity in colorectal cancer patient-derived tumor xenograft models via autophagy and signaling mechanisms. PMID: 30026382 |