Primary Site >> Liver Cancer
Gene >> AXIN2
| 1. | |||||||||||
| Journal: | Oncogene. 2002 Jul 18;21(31):4863-71. | ||||||||||
| Title: | Mutational spectrum of beta-catenin, AXIN1, and AXIN2 in hepatocellular carcinomas and hepatoblastomas. | ||||||||||
| Author: | Taniguchi, Ken|Roberts, Lewis R|Aderca, Ileana N|Dong, Xiangyang|Qian, Chiping|Murphy, Linda M|Nagorney, David M|Burgart, Lawrence J|Roche, Patrick C|Smith, David I|Ross, Julie A|Liu, Wanguo | ||||||||||
| PMID: | 12101426 | ||||||||||
| 2. | |||||||||||
| Journal: | Mol Cell Biol. 2002 Feb;22(4):1184-93. | ||||||||||
| Title: | Negative feedback loop of Wnt signaling through upregulation of conductin/axin2 in colorectal and liver tumors. | ||||||||||
| Author: | Lustig, Barbara|Jerchow, Boris|Sachs, Martin|Weiler, Sigrid|Pietsch, Torsten|Karsten, Uwe|van de Wetering, Marc|Clevers, Hans|Schlag, Peter M|Birchmeier, Walter|Behrens, Jurgen | ||||||||||
| PMID: | 11809809 | ||||||||||
| 3. | |||||||||||
| Journal: | Int J Oncol. 2004 May;24(5):1077-83. | ||||||||||
| Title: | Immunohistochemical analysis and mutational analyses of beta-catenin, Axin family and APC genes in hepatocellular carcinomas. | ||||||||||
| Author: | Ishizaki, Yasuyo|Ikeda, Satoshi|Fujimori, Masahiko|Shimizu, Yosuke|Kurihara, Takeshi|Itamoto, Toshiyuki|Kikuchi, Akira|Okajima, Masazumi|Asahara, Toshimasa | ||||||||||
| PMID: | 15067328 | ||||||||||
| 4. | |||||||||||
| Journal: | Clin Cancer Res. 2005 Jun 15;11(12):4295-304. | ||||||||||
| Title: | Elevated expression of Wnt antagonists is a common event in hepatoblastomas. | ||||||||||
| Author: | Koch, Arend|Waha, Andreas|Hartmann, Wolfgang|Hrychyk, Aksana|Schuller, Ulrich|Waha, Anke|Wharton, Keith A Jr|Fuchs, Serge Y|von Schweinitz, Dietrich|Pietsch, Torsten | ||||||||||
| PMID: | 15958610 | ||||||||||
| 5. | |||||||||||
| Journal: | J Gastroenterol. 2008;43(5):378-89. | ||||||||||
| Title: | Frequent epigenetic inactivation of SFRP genes in hepatocellular carcinoma. | ||||||||||
| Author: | Takagi, Hideyasu|Sasaki, Shigeru|Suzuki, Hiromu|Toyota, Minoru|Maruyama, Reo|Nojima, Masanori|Yamamoto, Hiroyuki|Omata, Masao|Tokino, Takashi|Imai, Kohzoh|Shinomura, Yasuhisa | ||||||||||
| PMID: | 18592156 | ||||||||||
| 6. | |||||||||||
| Journal: | Toxicology. 2009 Jun 16;260(1-3):104-11. | ||||||||||
| Title: | 2,2',4,4',5,5'-hexachlorobiphenyl (PCB 153) induces degradation of adherens junction proteins and inhibits beta-catenin-dependent transcription in liver epithelial cells. | ||||||||||
| Author: | Simeckova, P|Vondracek, J|Prochazkova, J|Kozubik, A|Krcmar, P|Machala, M | ||||||||||
| PMID: | 19464575 | ||||||||||
| 7. | |||||||||||
| Journal: | Cancer Res. 2011 Jun 1;71(11):4028-39. | ||||||||||
| Title: | EZH2-mediated concordant repression of Wnt antagonists promotes beta-catenin-dependent hepatocarcinogenesis. | ||||||||||
| Author: | Cheng, Alfred S L|Lau, Suki S|Chen, Yangchao|Kondo, Yutaka|Li, May S|Feng, Hai|Ching, Arthur K|Cheung, Kin F|Wong, Hoi K|Tong, Joanna H|Jin, Hongchuan|Choy, Kwong W|Yu, Jun|To, Ka F|Wong, Nathalie|Huang, Tim H-M|Sung, Joseph J Y | ||||||||||
| PMID: | 21512140 | ||||||||||
| 8. | |||||||||||
| Journal: | Clin Exp Metastasis. 2013 Jun;30(5):681-93. | ||||||||||
| Title: | Increased growth of colorectal liver metastasis following partial hepatectomy. | ||||||||||
| Author: | Krause, P|Flikweert, H|Monin, M|Seif Amir Hosseini, A|Helms, G|Cantanhede, G|Ghadimi, B M|Koenig, S | ||||||||||
| PMID: | 23385555 | ||||||||||
| 9. | |||||||||||
| Journal: | Liver Int. 2013 Aug;33(7):1100-12. | ||||||||||
| Title: | Upregulation of T-cell factor-4 isoform-responsive target genes in hepatocellular carcinoma. | ||||||||||
| Author: | Tomimaru, Yoshito|Koga, Hironori|Yano, Hirohisa|de la Monte, Suzanne|Wands, Jack R|Kim, Miran | ||||||||||
| PMID: | 23651211 | ||||||||||
| 10. | |||||||||||
| Journal: | Tumour Biol. 2014 Nov;35(11):11301-9. | ||||||||||
| Title: | Hsa-miR-195 targets PCMT1 in hepatocellular carcinoma that increases tumor life span. | ||||||||||
| Author: | Amer, Marwa|Elhefnawi, M|El-Ahwany, Eman|Awad, A F|Gawad, Nermen Abdel|Zada, Suher|Tawab, F M Abdel | ||||||||||
| PMID: | 25119594 | ||||||||||
| 11. | |||||||||||
| Journal: | Fam Cancer. 2015 Jun;14(2):325-31. | ||||||||||
| Title: | The roles of AXIN2 in tumorigenesis and epigenetic regulation. | ||||||||||
| Author: | Li, Shuang|Wang, Chunpeng|Liu, Xiaodong|Hua, Shucheng|Liu, Xin | ||||||||||
| PMID: | 25504512 | ||||||||||
| 12. | |||||||||||
| Journal: | Int J Clin Exp Pathol. 2015 May 1;8(5):5168-74. eCollection 2015. | ||||||||||
| Title: | miR-107 promotes hepatocellular carcinoma cell proliferation by targeting Axin2. | ||||||||||
| Author: | Zhang, Jun-Jie|Wang, Chen-Yu|Hua, Long|Yao, Kun-Hou|Chen, Jiang-Tao|Hu, Jun-Hong | ||||||||||
| PMID: | 26191213 | ||||||||||
| 13. | |||||||||||
| Journal: | Oncotarget. 2015 Sep 22;6(28):25390-401. | ||||||||||
| Title: | Tankyrase inhibitors attenuate WNT/beta-catenin signaling and inhibit growth of hepatocellular carcinoma cells. | ||||||||||
| Author: | Ma, Li|Wang, Xiaolin|Jia, Tao|Wei, Wei|Chua, Mei-Sze|So, Samuel | ||||||||||
| PMID: | 26246473 | ||||||||||
| 14. | |||||||||||
| Journal: | Mol Oncol. 2016 Feb;10(2):195-212. | ||||||||||
| Title: | 5-Hydroxytryptamine promotes hepatocellular carcinoma proliferation by influencing beta-catenin. | ||||||||||
| Author: | Fatima, Sarwat|Shi, Xiaoke|Lin, Zesi|Chen, Guo-qing|Pan, Xiao-hua|Wu, Justin Che-Yuen|Ho, John W|Lee, Nikki P|Gao, Hengjun|Zhang, Ge|Lu, Aiping|Bian, Zhao Xiang | ||||||||||
| PMID: | 26474915 | ||||||||||
| 15. | |||||||||||
| Journal: | Hepatology. 2016 Dec;64(6):2062-2076. | ||||||||||
| Title: | Octamer 4/microRNA-1246 signaling axis drives Wnt/beta-catenin activation in liver cancer stem cells. | ||||||||||
| Author: | Chai, Stella|Ng, Kai-Yu|Tong, Man|Lau, Eunice Y|Lee, Terence K|Chan, Kwok Wah|Yuan, Yun-Fei|Cheung, Tan-To|Cheung, Siu-Tim|Wang, Xiao-Qi|Wong, Nathalie|Lo, Chung-Mau|Man, Kwan|Guan, Xin-Yuan|Ma, Stephanie | ||||||||||
| PMID: | 27639189 | ||||||||||
| 16. | |||||||||||
| Journal: | PLoS One. 2016 Apr 21;11(4):e0152695. | ||||||||||
| Title: | Diverse Basis of beta-Catenin Activation in Human Hepatocellular Carcinoma: Implications in Biology and Prognosis. | ||||||||||
| Author: | Okabe, Hirohisa|Kinoshita, Hiroki|Imai, Katsunori|Nakagawa, Shigeki|Higashi, Takaaki|Arima, Kota|Uchiyama, Hideaki|Ikegami, Toru|Harimoto, Norifumi|Itoh, Shinji|Ishiko, Takatoshi|Yoshizumi, Tomoharu|Beppu, Toru|Monga, Satdarshan P S|Baba, Hideo|Maehara, Y | ||||||||||
| PMID: | 27100093 | ||||||||||
| 17. | |||||||||||
| Journal: | Clin Biochem. 2016 Jul;49(10-11):792-801. | ||||||||||
| Title: | Genetic polymorphisms in the Wnt/beta-catenin pathway genes as predictors of tumor development and survival in patients with hepatitis B virus-associated hepatocellular carcinoma. | ||||||||||
| Author: | Kim, Soon Sun|Cho, Hyo Jung|Lee, Hyun-Young|Park, Ju Han|Noh, Choong Kyun|Shin, Sung Jae|Lee, Kee Myung|Yoo, Byung Moo|Lee, Kwang Jae|Cho, Sung Won|Cheong, Jae Youn | ||||||||||
| PMID: | 26968103 | ||||||||||
| 18. | |||||||||||
| Journal: | Neuro Endocrinol Lett. 2017 Jul;38(3):131-137. | ||||||||||
| Title: | Mutations in AXIN2 gene as a risk factor for tooth agenesis and cancer: A review. | ||||||||||
| Author: | Hlouskova, Alena|Bielik, Peter|Bonczek, Ondrej|Balcar, Vladimir J|Sery, Omar | ||||||||||
| PMID: | 28759178 | ||||||||||
| 19. | |||||||||||
| Journal: | Oncogene. 2017 Nov 30;36(48):6725-6737. | ||||||||||
| Title: | Autophagy-dependent generation of Axin2+ cancer stem-like cells promotes hepatocarcinogenesis in liver cirrhosis. | ||||||||||
| Author: | Li, J|Hu, S B|Wang, L Y|Zhang, X|Zhou, X|Yang, B|Li, J H|Xiong, J|Liu, N|Li, Y|Wu, Y Z|Zheng, Q C | ||||||||||
| PMID: | 28783177 | ||||||||||
| 20. | |||||||||||
| Journal: | J Exp Clin Cancer Res. 2017 Sep 29;36(1):134. | ||||||||||
| Title: | Kindlin-2 promotes hepatocellular carcinoma invasion and metastasis by increasing Wnt/beta-catenin signaling. | ||||||||||
| Author: | Lin, Jie|Lin, Wansong|Ye, Yunbin|Wang, Liping|Chen, Xiaoyan|Zang, Shengbing|Huang, Aimin | ||||||||||
| PMID: | 28969700 | ||||||||||
| 21. | |||||||||||
| Journal: | Oncotarget. 2017 Sep 28;8(70):114526-114539. | ||||||||||
| Title: | Oncogenic dependency on beta-catenin in liver cancer cell lines correlates with pathway activation. | ||||||||||
| Author: | Ding, Zhihu|Shi, Chaomei|Jiang, Lan|Tolstykh, Tatiana|Cao, Hui|Bangari, Dinesh S|Ryan, Susan|Levit, Mikhail|Jin, Taiguang|Mamaat, Karl|Yu, Qunyan|Qu, Hui|Hopke, Joern|Cindhuchao, May|Hoffmann, Dietmar|Sun, Fangxian|Helms, Mike W|Jahn-Hofmann, Kerstin|Sche | ||||||||||
| PMID: | 29383099 | ||||||||||
| 22. | |||||||||||
| Journal: | Am J Pathol. 2018 Feb;188(2):378-391. | ||||||||||
| Title: | Overexpression of MUC13, a Poor Prognostic Predictor, Promotes Cell Growth by Activating Wnt Signaling in Hepatocellular Carcinoma. | ||||||||||
| Author: | Dai, Yongdong|Liu, Lulu|Zeng, Tingting|Liang, Jian-Zhong|Song, Ye|Chen, Kai|Li, Yan|Chen, Leilei|Zhu, Ying-Hui|Li, Jiangchao|Li, Yan|Xie, Dan|Yuan, Yun-Fei|Guan, Xin-Yuan | ||||||||||
| PMID: | 29174628 | ||||||||||
| 23. | |||||||||||
| Journal: | Cell Death Differ. 2018 Aug;25(8):1426-1441. | ||||||||||
| Title: | Cripto-1 contributes to stemness in hepatocellular carcinoma by stabilizing Dishevelled-3 and activating Wnt/beta-catenin pathway. | ||||||||||
| Author: | Lo, Regina Cheuk-Lam|Leung, Carmen Oi-Ning|Chan, Kristy Kwan-Shuen|Ho, Daniel Wai-Hung|Wong, Chun-Ming|Lee, Terence Kin-Wah|Ng, Irene Oi-Lin | ||||||||||
| PMID: | 29445127 | ||||||||||
| 24. | |||||||||||
| Journal: | Int J Mol Med. 2018 Aug;42(2):713-725. | ||||||||||
| Title: | Multilayered prevention and treatment of chronic inflammation, organ fibrosis and cancer associated with canonical WNT/betacatenin signaling activation (Review). | ||||||||||
| Author: | Katoh, Masaru | ||||||||||
| PMID: | 29786110 | ||||||||||
| 25. | |||||||||||
| Journal: | Am J Pathol. 2018 Sep 8. pii: S0002-9440(17)31145-8. | ||||||||||
| Title: | High Frequency of beta-Catenin Mutations in Mouse Hepatocellular Carcinomas Induced by a Nongenotoxic Constitutive Androstane Receptor Agonist. | ||||||||||
| Author: | Mattu, Sandra|Saliba, Christian|Sulas, Pia|Zavattari, Patrizia|Perra, Andrea|Kowalik, Marta A|Monga, Satdarshan P|Columbano, Amedeo | ||||||||||
| PMID: | 30201494 | ||||||||||
| 26. | |||||||||||
| Journal: | Mol Cancer Res. 2018 Sep 26. pii: 1541-7786.MCR-18-0054. | ||||||||||
| Title: | Oncogenic STRAP Supports Hepatocellular Carcinoma Growth by Enhancing Wnt/beta-Catenin Signaling. | ||||||||||
| Author: | Wang, Wenhui|Li, Shan|Liu, Pengyu|Sideras, Kostandinos|van de Werken, Harmen J G|van der Heide, Marieke|Cao, Wanlu|Lavrijsen, Marla|Peppelenbosch, Maikel P|Bruno, Marco|Pan, Qiuwei|Smits, Ron | ||||||||||
| PMID: | 30257989 | ||||||||||