Primary Site >> Liver Cancer
Gene >> AXIN2
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Ref: Negative feedback loop of Wnt signaling through upregulation of conductin/axin2 in colorectal and liver tumors. PMID: 11809809 Ref: Mutational spectrum of beta-catenin, AXIN1, and AXIN2 in hepatocellular carcinomas and hepatoblastomas. PMID: 12101426 |
Ref: Immunohistochemical analysis and mutational analyses of beta-catenin, Axin family and APC genes in hepatocellular carcinomas. PMID: 15067328 |
Ref: Elevated expression of Wnt antagonists is a common event in hepatoblastomas. PMID: 15958610 |
Ref: Frequent epigenetic inactivation of SFRP genes in hepatocellular carcinoma. PMID: 18592156 |
Ref: 2,2',4,4',5,5'-hexachlorobiphenyl (PCB 153) induces degradation of adherens junction proteins and inhibits beta-catenin-dependent transcription in liver epithelial cells. PMID: 19464575 |
Ref: EZH2-mediated concordant repression of Wnt antagonists promotes beta-catenin-dependent hepatocarcinogenesis. PMID: 21512140 |
Ref: Increased growth of colorectal liver metastasis following partial hepatectomy. PMID: 23385555 Ref: Upregulation of T-cell factor-4 isoform-responsive target genes in hepatocellular carcinoma. PMID: 23651211 |
Ref: Hsa-miR-195 targets PCMT1 in hepatocellular carcinoma that increases tumor life span. PMID: 25119594 |
Ref: The roles of AXIN2 in tumorigenesis and epigenetic regulation. PMID: 25504512 Ref: miR-107 promotes hepatocellular carcinoma cell proliferation by targeting Axin2. PMID: 26191213 Ref: Tankyrase inhibitors attenuate WNT/beta-catenin signaling and inhibit growth of hepatocellular carcinoma cells. PMID: 26246473 |
Ref: 5-Hydroxytryptamine promotes hepatocellular carcinoma proliferation by influencing beta-catenin. PMID: 26474915 Ref: Genetic polymorphisms in the Wnt/beta-catenin pathway genes as predictors of tumor development and survival in patients with hepatitis B virus-associated hepatocellular carcinoma. PMID: 26968103 Ref: Diverse Basis of beta-Catenin Activation in Human Hepatocellular Carcinoma: Implications in Biology and Prognosis. PMID: 27100093 Ref: Octamer 4/microRNA-1246 signaling axis drives Wnt/beta-catenin activation in liver cancer stem cells. PMID: 27639189 |
Ref: Mutations in AXIN2 gene as a risk factor for tooth agenesis and cancer: A review. PMID: 28759178 Ref: Autophagy-dependent generation of Axin2+ cancer stem-like cells promotes hepatocarcinogenesis in liver cirrhosis. PMID: 28783177 Ref: Kindlin-2 promotes hepatocellular carcinoma invasion and metastasis by increasing Wnt/beta-catenin signaling. PMID: 28969700 Ref: Oncogenic dependency on beta-catenin in liver cancer cell lines correlates with pathway activation. PMID: 29383099 |
Ref: Overexpression of MUC13, a Poor Prognostic Predictor, Promotes Cell Growth by Activating Wnt Signaling in Hepatocellular Carcinoma. PMID: 29174628 Ref: Cripto-1 contributes to stemness in hepatocellular carcinoma by stabilizing Dishevelled-3 and activating Wnt/beta-catenin pathway. PMID: 29445127 Ref: Multilayered prevention and treatment of chronic inflammation, organ fibrosis and cancer associated with canonical WNT/betacatenin signaling activation (Review). PMID: 29786110 Ref: High Frequency of beta-Catenin Mutations in Mouse Hepatocellular Carcinomas Induced by a Nongenotoxic Constitutive Androstane Receptor Agonist. PMID: 30201494 Ref: Oncogenic STRAP Supports Hepatocellular Carcinoma Growth by Enhancing Wnt/beta-Catenin Signaling. PMID: 30257989 |