Primary Site >> Colorectal Cancer

Gene >> AXIN2

Journal: Curr Biol. 1999 Jan 28;9(2):105-8.
Title: Identification of APC2, a homologue of the adenomatous polyposis coli tumour suppressor.
Author: van Es, J H|Kirkpatrick, C|van de Wetering, M|Molenaar, M|Miles, A|Kuipers, J|Destree, O|Peifer, M|Clevers, H
PMID: 10021369
Journal: Bioessays. 1999 Dec;21(12):1021-30.
Title: beta-catenin signaling and cancer.
Author: Morin, P J
PMID: 10580987
Journal: Nat Genet. 2000 Oct;26(2):146-7.
Title: Mutations in AXIN2 cause colorectal cancer with defective mismatch repair by activating beta-catenin/TCF signalling.
Author: Liu, W|Dong, X|Mai, M|Seelan, R S|Taniguchi, K|Krishnadath, K K|Halling, K C|Cunningham, J M|Boardman, L A|Qian, C|Christensen, E|Schmidt, S S|Roche, P C|Smith, D I|Thibodeau, S N
PMID: 11017067
Journal: Proc Natl Acad Sci U S A. 2001 Dec 18;98(26):14973-8.
Title: Elevated expression of axin2 and hnkd mRNA provides evidence that Wnt/beta -catenin signaling is activated in human colon tumors.
Author: Yan, D|Wiesmann, M|Rohan, M|Chan, V|Jefferson, A B|Guo, L|Sakamoto, D|Caothien, R H|Fuller, J H|Reinhard, C|Garcia, P D|Randazzo, F M|Escobedo, J|Fantl, W J|Williams, L T
PMID: 11752446
Journal: Mol Cell Biol. 2002 Feb;22(4):1184-93.
Title: Negative feedback loop of Wnt signaling through upregulation of conductin/axin2 in colorectal and liver tumors.
Author: Lustig, Barbara|Jerchow, Boris|Sachs, Martin|Weiler, Sigrid|Pietsch, Torsten|Karsten, Uwe|van de Wetering, Marc|Clevers, Hans|Schlag, Peter M|Birchmeier, Walter|Behrens, Jurgen
PMID: 11809809
Journal: Biol Chem. 2002 Feb;383(2):255-61.
Title: TCF: Lady Justice casting the final verdict on the outcome of Wnt signalling.
Author: Brantjes, Helen|Barker, Nick|van Es, Johan|Clevers, Hans
PMID: 11934263
Journal: Proc Natl Acad Sci U S A. 2002 Jun 25;99(13):8683-8. Epub 2002 Jun 18.
Title: Subcellular distribution of Wnt pathway proteins in normal and neoplastic colon.
Author: Anderson, Christine B|Neufeld, Kristi L|White, Raymond L
PMID: 12072559
Journal: Anticancer Res. 2002 Nov-Dec;22(6A):3409-14.
Title: Overexpression of Wnt target genes in adenomas of familial adenomatous polyposis patients.
Author: D'Orazio, Daniel|Muller, Patrick Y|Heinimann, Karl|Albrecht, Christiane|Bendik, Igor|Herzog, Urs|Tondelli, Peter|Bauerfeind, Peter|Muller, Hansjakob|Dobbie, Zuzana
PMID: 12530096
Journal: Genes Chromosomes Cancer. 2004 Feb;39(2):138-42.
Title: Activated BRAF targets proximal colon tumors with mismatch repair deficiency and MLH1 inactivation.
Author: Domingo, Enric|Espin, Eloi|Armengol, Manel|Oliveira, Carla|Pinto, Mafalda|Duval, Alex|Brennetot, Caroline|Seruca, Raquel|Hamelin, Richard|Yamamoto, Hiroyuki|Schwartz, Simo Jr
PMID: 14695993
Journal: Nat Genet. 2004 Apr;36(4):417-22. Epub 2004 Mar 14.
Title: Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer.
Author: Suzuki, Hiromu|Watkins, D Neil|Jair, Kam-Wing|Schuebel, Kornel E|Markowitz, Sanford D|Chen, Wei Dong|Pretlow, Theresa P|Yang, Bin|Akiyama, Yoshimitsu|Van Engeland, Manon|Toyota, Minoru|Tokino, Takashi|Hinoda, Yuji|Imai, Kohzoh|Herman, James G|Baylin, Step
PMID: 15034581
Journal: Am J Hum Genet. 2004 May;74(5):1043-50. Epub 2004 Mar 23.
Title: Mutations in AXIN2 cause familial tooth agenesis and predispose to colorectal cancer.
Author: Lammi, Laura|Arte, Sirpa|Somer, Mirja|Jarvinen, Heikki|Lahermo, Paivi|Thesleff, Irma|Pirinen, Sinikka|Nieminen, Pekka
PMID: 15042511
Journal: Oncogene. 2005 Apr 21;24(18):3054-8.
Title: Blockade of Wnt-1 signaling induces apoptosis in human colorectal cancer cells containing downstream mutations.
Author: He, Biao|Reguart, Noemi|You, Liang|Mazieres, Julien|Xu, Zhidong|Lee, Amie Y|Mikami, Iwao|McCormick, Frank|Jablons, David M
PMID: 15735684
Journal: Hum Mutat. 2005 May;25(5):498-500.
Title: Germline mutations of AXIN2 are not associated with nonsyndromic colorectal cancer.
Author: Peterlongo, Paolo|Howe, Louise R|Radice, Paolo|Sala, Paola|Hong, Young-Joon|Hong, Seok-Il|Mitra, Nandita|Offit, Kenneth|Ellis, Nathan A
PMID: 15841489
Journal: J Cell Sci. 2005 Jul 15;118(Pt 14):3117-29.
Title: The histidine triad protein Hint1 interacts with Pontin and Reptin and inhibits TCF-beta-catenin-mediated transcription.
Author: Weiske, Jorg|Huber, Otmar
PMID: 16014379
Journal: Int J Oncol. 2005 Dec;27(6):1483-7.
Title: Identification of SP5 as a downstream gene of the beta-catenin/Tcf pathway and its enhanced expression in human colon cancer.
Author: Takahashi, Meiko|Nakamura, Yusuke|Obama, Kazutaka|Furukawa, Yoichi
PMID: 16273202
Journal: Cancer Lett. 2006 Feb 28;233(2):338-47.
Title: Regulation of axin2 expression at the levels of transcription, translation and protein stability in lung and colon cancer.
Author: Hughes, Thomas A|Brady, Hugh J M
PMID: 15885887
Journal: Oncogene. 2006 Jan 5;25(1):139-46.
Title: Epigenetic silencing of AXIN2 in colorectal carcinoma with microsatellite instability.
Author: Koinuma, K|Yamashita, Y|Liu, W|Hatanaka, H|Kurashina, K|Wada, T|Takada, S|Kaneda, R|Choi, Y L|Fujiwara, S-I|Miyakura, Y|Nagai, H|Mano, H
PMID: 16247484
Journal: Hum Pathol. 2006 Feb;37(2):212-7.
Title: Expression of Wnt-signaling pathway proteins in intraductal papillary mucinous neoplasms of the pancreas: a tissue microarray analysis.
Author: Chetty, Runjan|Serra, Stefano|Salahshor, Sima|Alsaad, Khaled|Shih, Warren|Blaszyk, Hagen|Woodgett, James R|Tsao, Ming-Sound
PMID: 16426922
Journal: Int J Cancer. 2006 Oct 15;119(8):1837-42.
Title: Mutations within Wnt pathway genes in sporadic colorectal cancers and cell lines.
Author: Suraweera, Nirosha|Robinson, James|Volikos, Emmanuoil|Guenther, Thomas|Talbot, Ian|Tomlinson, Ian|Silver, Andrew
PMID: 16708370
Journal: FEBS Lett. 2006 Jun 26;580(15):3665-70. Epub 2006 Jun 5.
Title: Wnt pathway mutations selected by optimal beta-catenin signaling for tumorigenesis.
Author: Cho, Kwang-Hyun|Baek, Songjoon|Sung, Myong-Hee
PMID: 16764864
Journal: Proc Natl Acad Sci U S A. 2006 Jul 11;103(28):10747-52. Epub 2006 Jun 30.
Title: Aberrant Wnt/beta-catenin signaling can induce chromosomal instability in colon cancer.
Author: Hadjihannas, Michel V|Bruckner, Martina|Jerchow, Boris|Birchmeier, Walter|Dietmaier, Wolfgang|Behrens, Jurgen
PMID: 16815967
Journal: Int J Mol Med. 2006 Aug;18(2):279-84.
Title: Single nucleotide polymorphism of the AXIN2 gene is preferentially associated with human lung cancer risk in a Japanese population.
Author: Kanzaki, Hirotaka|Ouchida, Mamoru|Hanafusa, Hiroko|Yano, Masaaki|Suzuki, Hiromitsu|Aoe, Motoi|Imai, Kazue|Shimizu, Nobuyoshi|Nakachi, Kei|Shimizu, Kenji
PMID: 16820935
Journal: Hum Mutat. 2006 Oct;27(10):1064.
Title: Low frequency of AXIN2 mutations and high frequency of MUTYH mutations in patients with multiple polyposis.
Author: Lejeune, Sophie|Guillemot, Francois|Triboulet, Jean-Pierre|Cattan, Stephane|Mouton, Christine|Porchet, Nicole|Manouvrier, Sylvie|Buisine, Marie-Pierre
PMID: 16941501
Journal: Cell Cycle. 2006 Sep;5(18):2077-81. Epub 2006 Sep 15.
Title: CIN By WNT: growth pathways, mitotic control and chromosomal instability in cancer.
Author: Hadjihannas, Michel V|Behrens, Jurgen
PMID: 16969101
Journal: Oncogene. 2006 Dec 4;25(57):7531-7.
Title: Colorectal cancer and genetic alterations in the Wnt pathway.
Author: Segditsas, S|Tomlinson, I
PMID: 17143297
Journal: Hum Mol Genet. 2007 Jan 15;16(2):199-209. Epub 2006 Dec 22.
Title: Truncated APC regulates the transcriptional activity of beta-catenin in a cell cycle dependent manner.
Author: Schneikert, Jean|Grohmann, Annette|Behrens, Jurgen
PMID: 17189293
Journal: Gastroenterology. 2007 Feb;132(2):527-30. Epub 2006 Nov 29.
Title: Homozygous PMS2 deletion causes a severe colorectal cancer and multiple adenoma phenotype without extraintestinal cancer.
Author: Will, Olivia|Carvajal-Carmona, Luis G|Gorman, Patricia|Howarth, Kimberley M|Jones, Angela M|Polanco-Echeverry, Guadalupe M|Chinaleong, Jo-Anne|Gunther, Thomas|Silver, Andrew|Clark, Susan K|Tomlinson, Ian
PMID: 17258725
Journal: Ai Zheng. 2007 Mar;26(3):264-9.
Title: [Mechanism study of antisense cyclin B1 in tumorigenesis inhibition using proteomic technique].
Author: Yang, Tao|Zhang, Ling|Yan, Fei|Tong, Ai-Ping|Liu, Xin-Yu|Liu, Huan-Yi|Huang, Can-Hua
PMID: 17355788
Journal: Ai Zheng. 2007 Oct;26(10):1041-6.
Title: [Mechanism of Wnt signaling pathway regulation by a truncated mutant of Axin2 in colorectal cancer].
Author: Wang, Feng-Wei|Wen, Ling|Zhu, Si-Wei|Yao, Qiang|Cai, Yu-Mei|Ma, Gang
PMID: 17927870
Journal: Mod Pathol. 2008 Mar;21(3):271-81. Epub 2007 Dec 14.
Title: Frequent accumulation of nuclear E-cadherin and alterations in the Wnt signaling pathway in esophageal squamous cell carcinomas.
Author: Salahshor, Sima|Naidoo, Richard|Serra, Stefano|Shih, Warren|Tsao, Ming-Sound|Chetty, Runjan|Woodgett, James R
PMID: 18084253
Journal: Genes Chromosomes Cancer. 2008 Jul;47(7):614-24.
Title: Concomitant activation of Wnt pathway and loss of mismatch repair function in human melanoma.
Author: Castiglia, Daniele|Bernardini, Silvia|Alvino, Ester|Pagani, Elena|De Luca, Naomi|Falcinelli, Sabrina|Pacchiarotti, Alberto|Bonmassar, Enzo|Zambruno, Giovanna|D'Atri, Stefania
PMID: 18384130
Journal: Cancer Sci. 2008 Jul;99(7):1348-54.
Title: Individual tumorigenesis pathways of sporadic colorectal adenocarcinomas are associated with the biological behavior of tumors.
Author: Kim, Jin C|Cho, Young K|Roh, Seon A|Yu, Chang S|Gong, Gyungyub|Jang, Se J|Kim, Seon Y|Kim, Yong S
PMID: 18422752
Journal: Eur J Med Genet. 2008 Jul-Aug;51(4):273-91.
Title: The genetic basis of inherited anomalies of the teeth. Part 1: clinical and molecular aspects of non-syndromic dental disorders.
Author: Bailleul-Forestier, Isabelle|Molla, Muriel|Verloes, Alain|Berdal, Ariane
PMID: 18499550
Journal: Br J Cancer. 2008 Jul 8;99(1):136-42.
Title: Profiling CpG island field methylation in both morphologically normal and neoplastic human colonic mucosa.
Author: Belshaw, N J|Elliott, G O|Foxall, R J|Dainty, J R|Pal, N|Coupe, A|Garg, D|Bradburn, D M|Mathers, J C|Johnson, I T
PMID: 18542073
Journal: Cancer Epidemiol Biomarkers Prev. 2008 Oct;17(10):2835-45.
Title: Diagnostic mRNA expression patterns of inflamed, benign, and malignant colorectal biopsy specimen and their correlation with peripheral blood results.
Author: Galamb, Orsolya|Sipos, Ferenc|Solymosi, Norbert|Spisak, Sandor|Krenacs, Tibor|Toth, Kinga|Tulassay, Zsolt|Molnar, Bela
PMID: 18843029
Journal: Birth Defects Res A Clin Mol Teratol. 2009 Feb;85(2):169-73.
Title: AXIN2 and CDH1 polymorphisms, tooth agenesis, and oral clefts.
Author: Letra, Ariadne|Menezes, Renato|Granjeiro, Jose M|Vieira, Alexandre R
PMID: 18683894
Journal: Arch Oral Biol. 2009 Jan;54(1):45-9.
Title: Axis inhibition protein 2 (AXIN2) polymorphisms and tooth agenesis.
Author: Callahan, N|Modesto, A|Meira, R|Seymen, F|Patir, A|Vieira, A R
PMID: 18790474
Journal: J Am Dent Assoc. 2009 Jan;140(1):80-4.
Title: AXIS inhibition protein 2, orofacial clefts and a family history of cancer.
Author: Menezes, Renato|Marazita, Mary Louise|Goldstein McHenry, Toby|Cooper, Margaret E|Bardi, Kathleen|Brandon, Carla|Letra, Ariadne|Martin, Rick A|Vieira, Alexandre Rezende
PMID: 19119171
Journal: Gastroenterology. 2009 Sep;137(3):902-13, 913.e1-11.
Title: Elevated Dnmt3a activity promotes polyposis in Apc(Min) mice by relaxing extracellular restraints on Wnt signaling.
Author: Samuel, Michael S|Suzuki, Hiromu|Buchert, Michael|Putoczki, Tracy L|Tebbutt, Niall C|Lundgren-May, Therese|Christou, Aliki|Inglese, Melissa|Toyota, Minoru|Heath, Joan K|Ward, Robyn L|Waring, Paul M|Ernst, Matthias
PMID: 19454286
Journal: Int J Oncol. 2009 Nov;35(5):977-82.
Title: Analysis of candidate target genes for mononucleotide repeat mutation in microsatellite instability-high (MSI-H) endometrial cancer.
Author: Kawaguchi, Makiko|Banno, Kouji|Yanokura, Megumi|Kobayashi, Yusuke|Kishimi, Arisa|Ogawa, Seiji|Kisu, Iori|Nomura, Hiroyuki|Hirasawa, Akira|Susumu, Nobuyuki|Aoki, Daisuke
PMID: 19787250
Journal: Oncogene. 2010 Mar 18;29(11):1663-71.
Title: Contribution of the 15 amino acid repeats of truncated APC to beta-catenin degradation and selection of APC mutations in colorectal tumours from FAP patients.
Author: Kohler, E M|Brauburger, K|Behrens, J|Schneikert, J
PMID: 19966865
Journal: Cancer Res. 2010 Aug 15;70(16):6629-38.
Title: Dvl2 promotes intestinal length and neoplasia in the ApcMin mouse model for colorectal cancer.
Author: Metcalfe, Ciara|Ibrahim, Ashraf E K|Graeb, Michael|de la Roche, Marc|Schwarz-Romond, Thomas|Fiedler, Marc|Winton, Douglas J|Corfield, Anthony|Bienz, Mariann
PMID: 20663899
Journal: BMC Cancer. 2010 Aug 9;10:413.
Title: Mutations in the WTX-gene are found in some high-grade microsatellite instable (MSI-H) colorectal cancers.
Author: Scheel, Silvio K|Porzner, Marc|Pfeiffer, Sabine|Ormanns, Steffen|Kirchner, Thomas|Jung, Andreas
PMID: 20696052
Journal: Cancer Res. 2011 Jan 1;71(1):197-205.
Title: Novel synthetic antagonists of canonical Wnt signaling inhibit colorectal cancer cell growth.
Author: Waaler, Jo|Machon, Ondrej|von Kries, Jens Peter|Wilson, Steven Ray|Lundenes, Elsa|Wedlich, Doris|Gradl, Dietmar|Paulsen, Jan Erik|Machonova, Olga|Dembinski, Jennifer L|Dinh, Huyen|Krauss, Stefan
PMID: 21199802
Journal: Cell Res. 2011 May;21(5):730-40.
Title: A diterpenoid derivative 15-oxospiramilactone inhibits Wnt/beta-catenin signaling and colon cancer cell tumorigenesis.
Author: Wang, Wei|Liu, Haiyang|Wang, Sheng|Hao, Xiaojiang|Li, Lin
PMID: 21321609
Journal: Mol Cell Biochem. 2011 Sep;355(1-2):149-55.
Title: Novelty of Axin 2 and lack of Axin 1 gene mutation in colorectal cancer: a study in Kashmiri population.
Author: Khan, Nighat P|Pandith, Arshad A|Hussain, Mahboob Ul|Yousuf, Adfar|Khan, Mosin S|Wani, Khursheed A|Mudassar, Syed
PMID: 21541676
Journal: Cancer Res. 2011 Dec 15;71(24):7628-39.
Title: Wnt inhibitor screen reveals iron dependence of beta-catenin signaling in cancers.
Author: Song, Siyuan|Christova, Tania|Perusini, Stephen|Alizadeh, Solmaz|Bao, Ren-Yue|Miller, Bryan W|Hurren, Rose|Jitkova, Yulia|Gronda, Marcela|Isaac, Methvin|Joseph, Babu|Subramaniam, Ratheesh|Aman, Ahmed|Chau, Anh|Hogge, Donna E|Weir, Scott J|Kasper, James|Sc
PMID: 22009536
Journal: Oncogene. 2012 May 10;31(19):2423-37.
Title: A knock-in mouse model reveals roles for nuclear Apc in cell proliferation, Wnt signal inhibition and tumor suppression.
Author: Zeineldin, M|Cunningham, J|McGuinness, W|Alltizer, P|Cowley, B|Blanchat, B|Xu, W|Pinson, D|Neufeld, K L
PMID: 21996741
Journal: Mol Biol Rep. 2012 May;39(5):6171-8.
Title: Epigenetic and genetic analysis of WNT signaling pathway in sporadic colorectal cancer patients from Iran.
Author: Naghibalhossaini, Fakhraddin|Zamani, Mozhdeh|Mokarram, Pooneh|Khalili, Islam|Rasti, Mozhgan|Mostafavi-Pour, Zohreh
PMID: 22207181
Journal: EMBO Rep. 2012 Apr;13(4):347-54.
Title: Cell cycle control of Wnt/beta-catenin signalling by conductin/axin2 through CDC20.
Author: Hadjihannas, Michel V|Bernkopf, Dominic B|Bruckner, Martina|Behrens, Jurgen
PMID: 22322943
Journal: Cancer Res. 2012 Jun 1;72(11):2822-32.
Title: A novel tankyrase inhibitor decreases canonical Wnt signaling in colon carcinoma cells and reduces tumor growth in conditional APC mutant mice.
Author: Waaler, Jo|Machon, Ondrej|Tumova, Lucie|Dinh, Huyen|Korinek, Vladimir|Wilson, Steven Ray|Paulsen, Jan Erik|Pedersen, Nina Marie|Eide, Tor J|Machonova, Olga|Gradl, Dietmar|Voronkov, Andrey|von Kries, Jens Peter|Krauss, Stefan
PMID: 22440753
Journal: Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):11312-7.
Title: Canonical Wnt suppressor, Axin2, promotes colon carcinoma oncogenic activity.
Author: Wu, Zhao-Qiu|Brabletz, Thomas|Fearon, Eric|Willis, Amanda L|Hu, Casey Yuexian|Li, Xiao-Yan|Weiss, Stephen J
PMID: 22745173
Journal: Biochem Pharmacol. 2012 Nov 1;84(9):1143-53.
Title: The beta-catenin/TCF complex as a novel target of resveratrol in the Wnt/beta-catenin signaling pathway.
Author: Chen, Hui-Jye|Hsu, Le-Shiang|Shia, Yu-Ting|Lin, Meng-Wei|Lin, Chung-Ming
PMID: 22935447
Journal: PLoS One. 2012;7(11):e48670.
Title: Inhibition of tankyrases induces Axin stabilization and blocks Wnt signalling in breast cancer cells.
Author: Bao, Renyue|Christova, Tania|Song, Siyuan|Angers, Stephane|Yan, Xiaojun|Attisano, Liliana
PMID: 23144924
Journal: Oncogene. 2013 Feb 14;32(7):883-93.
Title: In vivo and in vitro models for the therapeutic targeting of Wnt signaling using a Tet-ODeltaN89beta-catenin system.
Author: Jarde, T|Evans, R J|McQuillan, K L|Parry, L|Feng, G J|Alvares, B|Clarke, A R|Dale, T C
PMID: 22469981
Journal: Clin Exp Metastasis. 2013 Jun;30(5):681-93.
Title: Increased growth of colorectal liver metastasis following partial hepatectomy.
Author: Krause, P|Flikweert, H|Monin, M|Seif Amir Hosseini, A|Helms, G|Cantanhede, G|Ghadimi, B M|Koenig, S
PMID: 23385555
Journal: Carcinogenesis. 2013 Jun;34(6):1361-9.
Title: Regulation of APC and AXIN2 expression by intestinal tumor suppressor CDX2 in colon cancer cells.
Author: Olsen, Anders Kruger|Coskun, Mehmet|Bzorek, Michael|Kristensen, Michael Holmsgaard|Danielsen, Erik Thomas|Jorgensen, Steffen|Olsen, Jorgen|Engel, Ulla|Holck, Susanne|Troelsen, Jesper Thorvald
PMID: 23393221
Journal: Cell Cycle. 2013 May 15;12(10):1578-87.
Title: p53 regulates nuclear GSK-3 levels through miR-34-mediated Axin2 suppression in colorectal cancer cells.
Author: Kim, Nam Hee|Cha, Yong Hoon|Kang, Shi Eun|Lee, Yoonmi|Lee, Inhan|Cha, So Young|Ryu, Joo Kyung|Na, Jung Min|Park, Changbum|Yoon, Ho-Geun|Park, Gyeong-Ju|Yook, Jong In|Kim, Hyun Sil
PMID: 23624843
Journal: Gastroenterology. 2013 Aug;145(2):416-25.e1-4.
Title: IDO1 metabolites activate beta-catenin signaling to promote cancer cell proliferation and colon tumorigenesis in mice.
Author: Thaker, Ameet I|Rao, M Suprada|Bishnupuri, Kumar S|Kerr, Thomas A|Foster, Lynne|Marinshaw, Jeffrey M|Newberry, Rodney D|Stenson, William F|Ciorba, Matthew A
PMID: 23669411
Journal: Int J Colorectal Dis. 2013 Nov;28(11):1469-78.
Title: Expression and localization of axin 2 in colorectal carcinoma and its clinical implication.
Author: Schaal, Ute|Grenz, Sandra|Merkel, Susanne|Rau, Tilman T|Hadjihannas, Michel V|Kremmer, Elisabeth|Chudasama, Priya|Croner, Roland S|Behrens, Jurgen|Sturzl, Michael|Naschberger, Elisabeth
PMID: 23702820
Journal: Br J Cancer. 2013 Aug 6;109(3):667-75.
Title: Tumours with elevated levels of the Notch and Wnt pathways exhibit efficacy to PF-03084014, a gamma-secretase inhibitor, in a preclinical colorectal explant model.
Author: Arcaroli, J J|Quackenbush, K S|Purkey, A|Powell, R W|Pitts, T M|Bagby, S|Tan, A C|Cross, B|McPhillips, K|Song, E-K|Tai, W M|Winn, R A|Bikkavilli, K|Vanscoyk, M|Eckhardt, S G|Messersmith, W A
PMID: 23868008
Journal: PLoS One. 2013 Aug 12;8(8):e71755.
Title: Distinct gene expression signatures in lynch syndrome and familial colorectal cancer type x.
Author: Dominguez-Valentin, Mev|Therkildsen, Christina|Veerla, Srinivas|Jonsson, Mats|Bernstein, Inge|Borg, Ake|Nilbert, Mef
PMID: 23951239
Journal: Bioorg Med Chem Lett. 2013 Nov 1;23(21):5814-20.
Title: Investigation of 3-aryl-pyrimido[5,4-e][1,2,4]triazine-5,7-diones as small molecule antagonists of beta-catenin/TCF transcription.
Author: Zeller, Jorg|Turbiak, Anjanette J|Powelson, Ian A|Lee, Surin|Sun, Duxin|Showalter, H D Hollis|Fearon, Eric R
PMID: 24060489
Journal: Anticancer Res. 2013 Oct;33(10):4573-84.
Title: The prognostic significance of WNT pathway in surgically-treated colorectal cancer: beta-catenin expression predicts for disease-free survival.
Author: Kamposioras, Konstantinos|Konstantara, Athina|Kotoula, Vassiliki|Lakis, Sotiris|Kouvatseas, George|Akriviadis, Evangelos|Vrettou, Eleni|Dionysopoulos, Dimitrios|Krikelis, Dimitrios|Papadopoulou, Kyriaki|Charalambous, Elpida|Chrisafi, Sofia|Konstantaras, C
PMID: 24123033
Journal: Pharmacogenomics J. 2014 Apr;14(2):142-50.
Title: Association of common gene variants in the WNT/beta-catenin pathway with colon cancer recurrence.
Author: Paez, D|Gerger, A|Zhang, W|Yang, D|Labonte, M J|Benhanim, L|Kahn, M|Lenz, F|Lenz, C|Ning, Y|Wakatsuki, T|Loupakis, F|Lenz, H-J
PMID: 23817222
Journal: FEBS J. 2014 Feb;281(3):787-801.
Title: Adenomatous polyposis coli (APC) membrane recruitment 3, a member of the APC membrane recruitment family of APC-binding proteins, is a positive regulator of Wnt-beta-catenin signalling.
Author: Brauburger, Katharina|Akyildiz, Senem|Ruppert, Jan G|Graeb, Michael|Bernkopf, Dominic B|Hadjihannas, Michel V|Behrens, Jurgen
PMID: 24251807
Journal: Biochem Biophys Res Commun. 2014 Jan 3;443(1):217-22.
Title: Nuclear AXIN2 represses MYC gene expression.
Author: Rennoll, Sherri A|Konsavage, Wesley M Jr|Yochum, Gregory S
PMID: 24299953
Journal: Carcinogenesis. 2014 Mar;35(3):606-12.
Title: Differential effects of 2- and 3-series E-prostaglandins on in vitro expansion of Lgr5+ colonic stem cells.
Author: Fan, Yang-Yi|Davidson, Laurie A|Callaway, Evelyn S|Goldsby, Jennifer S|Chapkin, Robert S
PMID: 24336194
Journal: BMC Genomics. 2014 Jan 28;15:74.
Title: Comprehensive analysis of beta-catenin target genes in colorectal carcinoma cell lines with deregulated Wnt/beta-catenin signaling.
Author: Herbst, Andreas|Jurinovic, Vindi|Krebs, Stefan|Thieme, Susanne E|Blum, Helmut|Goke, Burkhard|Kolligs, Frank T
PMID: 24467841
Journal: Clin Cancer Res. 2014 Mar 15;20(6):1687-97.
Title: A functional germline variant in GLI1 implicates hedgehog signaling in clinical outcome of stage II and III colon carcinoma patients.
Author: Szkandera, Joanna|Pichler, Martin|Absenger, Gudrun|Stotz, Michael|Weissmueller, Melanie|Samonigg, Hellmut|Asslaber, Martin|Lax, Sigurd|Leitner, Gerhard|Winder, Thomas|Renner, Wilfried|Gerger, Armin
PMID: 24470513
Journal: Carcinogenesis. 2014 May;35(5):1185-92.
Title: Involvement of CDX2 in the cross talk between TNF-alpha and Wnt signaling pathway in the colon cancer cell line Caco-2.
Author: Coskun, Mehmet|Olsen, Anders Kruger|Bzorek, Michael|Holck, Susanne|Engel, Ulla Hojholt|Nielsen, Ole Haagen|Troelsen, Jesper Thorvald
PMID: 24501326
Journal: Hered Cancer Clin Pract. 2014 Mar 10;12(1):7.
Title: Colorectal cancer and self-reported tooth agenesis.
Author: Lindor, Noralane M|Win, Aung Ko|Gallinger, Steven|Daftary, Darshana|Thibodeau, Stephen N|Silva, Renato|Letra, Ariadne
PMID: 24607150
Journal: Eur J Med Genet. 2014 Apr;57(5):235-9.
Title: Is there a link between ovarian cancer and tooth agenesis?
Author: Bonds, John|Pollan-White, Sarah|Xiang, Lilin|Mues, Gabriele|D'Souza, Rena
PMID: 24631698
Journal: Biochem Biophys Res Commun. 2014 Apr 18;446(4):1120-5.
Title: Targeted repression of AXIN2 and MYC gene expression using designer TALEs.
Author: Rennoll, Sherri A|Scott, Samantha A|Yochum, Gregory S
PMID: 24667606
Journal: PLoS One. 2014 Apr 10;9(4):e94413.
Title: different Roles for the axin interactions with the SAMP versus the second twenty amino acid repeat of adenomatous polyposis coli.
Author: Schneikert, Jean|Ruppert, Jan Gustav|Behrens, Jurgen|Wenzel, Eva Maria
PMID: 24722208
Journal: Nat Prod Bioprospect. 2014 Jun;4(3):135-40.
Title: Two Natural ent-kauranoids as Novel Wnt Signaling Inhibitors.
Author: Zhang, Jing|Kong, Ling-Mei|Zhan, Rui|Ye, Zhen-Nan|Pu, Jian-Xin|Sun, Han-Dong|Li, Yan
PMID: 24955294
Journal: BMC Cancer. 2014 Jun 25;14:466.
Title: DNA methylation alterations of AXIN2 in serrated adenomas and colon carcinomas with microsatellite instability.
Author: Muto, Yuta|Maeda, Takafumi|Suzuki, Koichi|Kato, Takaharu|Watanabe, Fumiaki|Kamiyama, Hidenori|Saito, Masaaki|Koizumi, Kei|Miyaki, Yuichiro|Konishi, Fumio|Alonso, Sergio|Perucho, Manuel|Rikiyama, Toshiki
PMID: 24964857
Journal: Cancer Lett. 2014 Dec 1;355(1):1-8.
Title: AXIN1 and AXIN2 variants in gastrointestinal cancers.
Author: Mazzoni, Serina M|Fearon, Eric R
PMID: 25236910
Journal: Mod Pathol. 2015 Jan;28(1):146-58.
Title: Distinct WNT/beta-catenin signaling activation in the serrated neoplasia pathway and the adenoma-carcinoma sequence of the colorectum.
Author: Murakami, Takashi|Mitomi, Hiroyuki|Saito, Tsuyoshi|Takahashi, Michiko|Sakamoto, Naoto|Fukui, Naoshi|Yao, Takashi|Watanabe, Sumio
PMID: 24925057
Journal: Oncogene. 2015 Sep 17;34(38):4914-27.
Title: Oncogenic KRAS signalling promotes the Wnt/beta-catenin pathway through LRP6 in colorectal cancer.
Author: Lemieux, E|Cagnol, S|Beaudry, K|Carrier, J|Rivard, N
PMID: 25500543
Journal: Fam Cancer. 2015 Jun;14(2):325-31.
Title: The roles of AXIN2 in tumorigenesis and epigenetic regulation.
Author: Li, Shuang|Wang, Chunpeng|Liu, Xiaodong|Hua, Shucheng|Liu, Xin
PMID: 25504512
Journal: Tumour Biol. 2015 May;36(5):3301-8.
Title: LYTAK1, a novel TAK1 inhibitor, suppresses KRAS mutant colorectal cancer cell growth in vitro and in vivo.
Author: Zhou, Jundong|Zheng, Bing|Ji, Jiansong|Shen, Fei|Min, Han|Liu, Biao|Wu, Jinchang|Zhang, Shuyu
PMID: 25524577
Journal: Carcinogenesis. 2015 Mar;36(3):318-26.
Title: A novel ent-kaurane diterpenoid executes antitumor function in colorectal cancer cells by inhibiting Wnt/beta-catenin signaling.
Author: Ye, Qi|Yao, Guangmin|Zhang, Mengke|Guo, Guoli|Hu, Yufeng|Jiang, Jue|Cheng, Ling|Shi, Jianguo|Li, Hua|Zhang, Yonghui|Liu, Hudan
PMID: 25600769
Journal: Mol Biol Cell. 2015 Jun 15;26(12):2375-84.
Title: Wnt ligand-dependent activation of the negative feedback regulator Nkd1.
Author: Larraguibel, Jahdiel|Weiss, Alexander R E|Pasula, Daniel J|Dhaliwal, Rasmeet S|Kondra, Roman|Van Raay, Terence J
PMID: 25904337
Journal: Neoplasia. 2015 May;17(5):463-72.
Title: An AXIN2 Mutant Allele Associated With Predisposition to Colorectal Neoplasia Has Context-Dependent Effects on AXIN2 Protein Function.
Author: Mazzoni, Serina M|Petty, Elizabeth M|Stoffel, Elena M|Fearon, Eric R
PMID: 26025668
Journal: Nutr J. 2015 Jun 19;14:62.
Title: Effects of a grape-supplemented diet on proliferation and Wnt signaling in the colonic mucosa are greatest for those over age 50 and with high arginine consumption.
Author: Holcombe, Randall F|Martinez, Micaela|Planutis, Kestutis|Planutiene, Marina
PMID: 26085034
Journal: Nat Commun. 2015 Oct 15;6:8640.
Title: Aberrantly expressed miR-582-3p maintains lung cancer stem cell-like traits by activating Wnt/beta-catenin signalling.
Author: Fang, Lishan|Cai, Junchao|Chen, Baixue|Wu, Shanshan|Li, Rong|Xu, Xiaonan|Yang, Yi|Guan, Hongyu|Zhu, Xun|Zhang, Le|Yuan, Jie|Wu, Jueheng|Li, Mengfeng
PMID: 26468775
Journal: J Exp Clin Cancer Res. 2015 Nov 21;34:142.
Title: A-kinase anchor protein 4 (AKAP4) a promising therapeutic target of colorectal cancer.
Author: Jagadish, Nirmala|Parashar, Deepak|Gupta, Namita|Agarwal, Sumit|Purohit, Sapna|Kumar, Vikash|Sharma, Aditi|Fatima, Rukhsar|Topno, Amos Prashant|Shaha, Chandrima|Suri, Anil
PMID: 26590805
Journal: J Mol Cell Biol. 2016 Apr;8(2):157-73.
Title: In vivo epigenetic reprogramming of primary human colon cancer cells enhances metastases.
Author: Singovski, Grigori|Bernal, Carolina|Kuciak, Monika|Siegl-Cachedenier, Irene|Conod, Arwen|Ruiz I Altaba, Ariel
PMID: 26031752
Journal: Int J Oncol. 2016 Jan;48(1):115-22.
Title: Characteristics of carbonic anhydrase 9 expressing cells in human intestinal crypt base.
Author: Takahashi, Hidekazu|Suzuki, Yozo|Nishimura, Junichi|Haraguchi, Naotsugu|Ohtsuka, Masahisa|Miyazaki, Susumu|Uemura, Mamoru|Hata, Taishi|Takemasa, Ichiro|Mizushima, Tsunekazu|Yamamoto, Hirofumi|Doki, Yuichiro|Mori, Masaki
PMID: 26648507
Journal: Oncotarget. 2016 Apr 5;7(14):17870-84.
Title: Chemopreventive activity of GEN-27, a genistein derivative, in colitis-associated cancer is mediated by p65-CDX2-beta-catenin axis.
Author: Du, Qianming|Wang, Yajing|Liu, Chao|Wang, Hong|Fan, Huimin|Li, Yan|Wang, Jianing|Zhang, Xu|Lu, Jinrong|Ji, Hui|Hu, Rong
PMID: 26910375
Journal: Oncogene. 2016 Sep 22;35(38):4990-9.
Title: Topoisomerase IIalpha mediates TCF-dependent epithelial-mesenchymal transition in colon cancer.
Author: Zhou, Q|Abraham, A D|Li, L|Babalmorad, A|Bagby, S|Arcaroli, J J|Hansen, R J|Valeriote, F A|Gustafson, D L|Schaack, J|Messersmith, W A|LaBarbera, D V
PMID: 26947016
Journal: Oncotarget. 2016 May 10;7(19):28273-85.
Title: The novel tankyrase inhibitor (AZ1366) enhances irinotecan activity in tumors that exhibit elevated tankyrase and irinotecan resistance.
Author: Quackenbush, Kevin S|Bagby, Stacey|Tai, Wai Meng|Messersmith, Wells A|Schreiber, Anna|Greene, Justin|Kim, Jihye|Wang, Guoliang|Purkey, Alicia|Pitts, Todd M|Nguyen, Anna|Gao, Dexiang|Blatchford, Patrick|Capasso, Anna|Schuller, Alwin G|Eckhardt, S Gail|Arca
PMID: 27070088
Journal: Eur J Oral Sci. 2016 Jun;124(3):228-33.
Title: Functional analysis of a novel missense mutation in AXIN2 associated with non-syndromic tooth agenesis.
Author: Yue, Haitang|Liang, Jia|Yang, Kai|Hua, Bo|Bian, Zhuan
PMID: 27090353
Journal: Carcinogenesis. 2016 Jul;37(7):731-739.
Title: Hsp70 exerts oncogenic activity in the Apc mutant Min mouse model.
Author: Tao, Yun|Messer, Jeannette S|Goss, Kathleen H|Hart, John|Bissonnette, Marc|Chang, Eugene B
PMID: 27207671
Journal: Genet Test Mol Biomarkers. 2016 Aug;20(8):438-44.
Title: AXIN2 Polymorphisms and Their Association with Colorectal Cancer in Mexican Patients.
Author: Rosales-Reynoso, Monica Alejandra|Arredondo-Valdez, Abril Renee|Wence-Chavez, Laura Ivonne|Barros-Nunez, Patricio|Gallegos-Arreola, Martha P|Flores-Martinez, Silvia Esperanza|Sanchez-Corona, Jose
PMID: 27228364
Journal: Carcinogenesis. 2016 Aug;37(8):751-8.
Title: Association of a let-7 miRNA binding region of TGFBR1 with hereditary mismatch repair proficient colorectal cancer (MSS HNPCC).
Author: Xicola, Rosa M|Bontu, Sneha|Doyle, Brian J|Rawson, Jamie|Garre, Pilar|Lee, Esther|de la Hoya, Miguel|Bessa, Xavier|Clofent, Joan|Bujanda, Luis|Balaguer, Francesc|Castellvi-Bel, Sergi|Alenda, Cristina|Jover, Rodrigo|Ruiz-Ponte, Clara|Syngal, Sapna|Andreu,
PMID: 27234654
Journal: Epigenetics. 2016 Aug 2;11(8):588-602.
Title: Aberrant DNA methylation of WNT pathway genes in the development and progression of CIMP-negative colorectal cancer.
Author: Galamb, Orsolya|Kalmar, Alexandra|Peterfia, Balint|Csabai, Istvan|Bodor, Andras|Ribli, Dezso|Krenacs, Tibor|Patai, Arpad V|Wichmann, Barnabas|Bartak, Barbara Kinga|Toth, Kinga|Valcz, Gabor|Spisak, Sandor|Tulassay, Zsolt|Molnar, Bela
PMID: 27245242
Journal: PLoS One. 2016 Aug 2;11(8):e0160507.
Title: Formation of Tankyrase Inhibitor-Induced Degradasomes Requires Proteasome Activity.
Author: Pedersen, Nina Marie|Thorvaldsen, Tor Espen|Schultz, Sebastian Wolfgang|Wenzel, Eva Maria|Stenmark, Harald
PMID: 27482906
Journal: Oncotarget. 2016 Dec 20;7(51):84258-84270.
Title: LDB1 overexpression is a negative prognostic factor in colorectal cancer.
Author: Garcia, Sebastian A|Swiersy, Anka|Radhakrishnan, Praveen|Branchi, Vittorio|Kanth Nanduri, Lahiri|Gyorffy, Balazs|Betzler, Alexander M|Bork, Ulrich|Kahlert, Christoph|Reissfelder, Christoph|Rahbari, Nuh N|Weitz, Jurgen|Scholch, Sebastian
PMID: 27713177
Journal: World J Gastroenterol. 2016 Oct 14;22(38):8528-8539.
Title: Special AT-rich sequence-binding protein 2 acts as a negative regulator of stemness in colorectal cancer cells.
Author: Li, Ying|Liu, Yu-Hong|Hu, Yu-Ying|Chen, Lin|Li, Jian-Ming
PMID: 27784965
Journal: Fam Cancer. 2017 Apr;16(2):195-203.
Title: Expanding the genotype-phenotype spectrum in hereditary colorectal cancer by gene panel testing.
Author: Rohlin, Anna|Rambech, Eva|Kvist, Anders|Torngren, Therese|Eiengard, Frida|Lundstam, Ulf|Zagoras, Theofanis|Gebre-Medhin, Samuel|Borg, Ake|Bjork, Jan|Nilbert, Mef|Nordling, Margareta
PMID: 27696107
Journal: PLoS One. 2017 Jan 20;12(1):e0170508.
Title: Differential Roles of AXIN1 and AXIN2 in Tankyrase Inhibitor-Induced Formation of Degradasomes and beta-Catenin Degradation.
Author: Thorvaldsen, Tor Espen|Pedersen, Nina Marie|Wenzel, Eva Maria|Stenmark, Harald
PMID: 28107521
Journal: Mol Cancer Ther. 2017 Apr;16(4):752-762.
Title: APC Mutations as a Potential Biomarker for Sensitivity to Tankyrase Inhibitors in Colorectal Cancer.
Author: Tanaka, Noritaka|Mashima, Tetsuo|Mizutani, Anna|Sato, Ayana|Aoyama, Aki|Gong, Bo|Yoshida, Haruka|Muramatsu, Yukiko|Nakata, Kento|Matsuura, Masaaki|Katayama, Ryohei|Nagayama, Satoshi|Fujita, Naoya|Sugimoto, Yoshikazu|Seimiya, Hiroyuki
PMID: 28179481
Journal: Theranostics. 2017 Jan 6;7(2):482-492.
Title: Functional Genomic mRNA Profiling of Colorectal Adenomas: Identification and in vivo Validation of CD44 and Splice Variant CD44v6 as Molecular Imaging Targets.
Author: Hartmans, Elmire|Orian-Rousseau, Veronique|Matzke-Ogi, Alexandra|Karrenbeld, Arend|de Groot, Derk Jan A|de Jong, Steven|van Dam, Gooitzen M|Fehrmann, Rudolf S N|Nagengast, Wouter B
PMID: 28255344
Journal: Oncogenesis. 2017 Apr 3;6(4):e308.
Title: Methylation of WNT target genes AXIN2 and DKK1 as robust biomarkers for recurrence prediction in stage II colon cancer.
Author: Kandimalla, R|Linnekamp, J F|van Hooff, S|Castells, A|Llor, X|Andreu, M|Jover, R|Goel, A|Medema, J P
PMID: 28368388
Journal: J BUON. 2017 Mar-Apr;22(2):431-436.
Title: Assessing the clinical utility of Wnt pathway markers in colorectal cancer.
Author: Veloudis, Georgios|Pappas, Apostolos|Gourgiotis, Stavros|Falidas, Evangelos|Dimitriou, Nikoletta|Karavokiros, Ioannis|Aggelou, Anastasios|Komborozos, Vasileios|Petraki, Constantina|Menounos, Panagiotis|Bramis, Ioannis|Bastounis, Elias|Pikoulis, Emmanouel
PMID: 28534366
Journal: J Nutr Biochem. 2017 Oct;48:29-35.
Title: omega-3 Polyunsaturated fatty acids and their cytochrome P450-derived metabolites suppress colorectal tumor development in mice.
Author: Wang, Weicang|Yang, Jun|Nimiya, Yoshiki|Lee, Kin Sing Stephen|Sanidad, Katherine|Qi, Weipeng|Sukamtoh, Elvira|Park, Yeonhwa|Liu, Zhenhua|Zhang, Guodong
PMID: 28672272
Journal: Tumour Biol. 2017 Jul;39(7):1010428317714899.
Title: Screening key genes and miRNAs in early-stage colon adenocarcinoma by RNA-sequencing.
Author: Liu, Jixi|Liu, Fang|Li, Xiaoou|Song, Xin|Zhou, Lei|Jie, Jianzheng
PMID: 28714374
Journal: Mol Cell Biochem. 2018 Apr;441(1-2):109-124.
Title: Lichen-derived caperatic acid and physodic acid inhibit Wnt signaling in colorectal cancer cells.
Author: Paluszczak, Jaroslaw|Kleszcz, Robert|Studzinska-Sroka, Elzbieta|Krajka-Kuzniak, Violetta
PMID: 28887754
Journal: Biochem Biophys Res Commun. 2018 Feb 5;496(2):302-308.
Title: miR-3120-5p promotes colon cancer stem cell stemness and invasiveness through targeting Axin2.
Author: Hongdan, Li|Feng, Li
PMID: 29307822
Journal: Genes Chromosomes Cancer. 2018 Jun;57(6):304-310.
Title: XPNPEP3 is a novel transcriptional target of canonical Wnt/beta-catenin signaling.
Author: Kumar, Raju|Kotapalli, Viswakalyan|Naz, Ashmala|Gowrishankar, Swarnalata|Rao, Satish|Pollack, Jonathan R|Bashyam, Murali Dharan
PMID: 29383790
Journal: Biochem Pharmacol. 2018 Jun;152:71-83.
Title: Esculetin suppresses tumor growth and metastasis by targeting Axin2/E-cadherin axis in colorectal cancer.
Author: Kim, Won Kyung|Byun, Woong Sub|Chung, Hwa-Jin|Oh, Jedo|Park, Hyen Joo|Choi, Jae Sue|Lee, Sang Kook
PMID: 29534875
Journal: Int J Mol Med. 2018 Aug;42(2):713-725.
Title: Multilayered prevention and treatment of chronic inflammation, organ fibrosis and cancer associated with canonical WNT/betacatenin signaling activation (Review).
Author: Katoh, Masaru
PMID: 29786110
Journal: Yonsei Med J. 2018 Jul;59(5):588-594.
Title: CpG Island Methylator Phenotype and Methylation of Wnt Pathway Genes Together Predict Survival in Patients with Colorectal Cancer.
Author: Kim, Se Hyun|Park, Kyu Hyun|Shin, Sang Joon|Lee, Kang Young|Kim, Tae Il|Kim, Nam Kyu|Rha, Sun Young|Ahn, Joong Bae
PMID: 29869456
Journal: J Cancer Res Ther. 2018 Apr-Jun;14(3):527-531.
Title: Tooth agenesis: A susceptible indicator for colorectal cancer?
Author: Paranjyothi, M V|Kumaraswamy, K L|Begum, Lubna Firdose|Manjunath, K|Basheer, Shaini
PMID: 29893310
Journal: J Pathol Transl Med. 2018 Sep;52(5):298-306.
Title: Prognostic Significance of EPHB2 Expression in Colorectal Cancer Progression.
Author: Jang, Bo Gun|Kim, Hye Sung|Chang, Weon Young|Bae, Jeong Mo|Kang, Gyeong Hoon
PMID: 30016858
Journal: Mol Cancer Res. 2018 Aug 2. pii: 1541-7786.MCR-18-0115.
Title: miR-155 Is Downregulated in Familial Adenomatous Polyposis and Modulates WNT Signaling by Targeting AXIN1 and TCF4.
Author: Prossomariti, Anna|Piazzi, Giulia|D'Angelo, Leonarda|Miccoli, Sara|Turchetti, Daniela|Alquati, Chiara|Montagna, Claudio|Bazzoli, Franco|Ricciardiello, Luigi
PMID: 30072583
Journal: Life Sci. 2018 Sep 15;209:267-273.
Title: Pimozide suppresses colorectal cancer via inhibition of Wnt/beta-catenin signaling pathway.
Author: Ren, Yonggang|Tao, Jia|Jiang, Zhen|Guo, Dongmei|Tang, Jiancai
PMID: 30107167
Journal: Carcinogenesis. 2018 Sep 11. pii: 5094840.
Title: Matricellular protein periostin promotes colitis-associated colon tumorigenesis in mice.
Author: Koh, Seong-Joon|Kim, Ji Won|Kim, Byeong Gwan|Lee, Kook Lae|Kim, Dae Woo|Kim, Joo Sung
PMID: 30204842
Journal: Med Sci Monit. 2018 Sep 19;24:6608-6616.
Title: Elevated G-Protein Receptor 125 (GPR125) Expression Predicts Good Outcomes in Colorectal Cancer and Inhibits Wnt/beta-Catenin Signaling Pathway.
Author: Wu, Yibin|Chen, Wenjie|Gong, Lifeng|Ke, Chongwei|Wang, Huipeng|Cai, Yuankun
PMID: 30231258
Journal: Cancer Sci. 2018 Sep 20.
Title: RK-287107, a potent and specific tankyrase inhibitor, blocks colorectal cancer cell growth in a preclinical model.
Author: Mizutani, Anna|Yashiroda, Yoko|Muramatsu, Yukiko|Yoshida, Haruka|Chikada, Tsubasa|Tsumura, Takeshi|Okue, Masayuki|Shirai, Fumiyuki|Fukami, Takahiro|Yoshida, Minoru|Seimiya, Hiroyuki
PMID: 30238564
Journal: Mol Cancer Res. 2018 Sep 26. pii: 1541-7786.MCR-18-0054.
Title: Oncogenic STRAP Supports Hepatocellular Carcinoma Growth by Enhancing Wnt/beta-Catenin Signaling.
Author: Wang, Wenhui|Li, Shan|Liu, Pengyu|Sideras, Kostandinos|van de Werken, Harmen J G|van der Heide, Marieke|Cao, Wanlu|Lavrijsen, Marla|Peppelenbosch, Maikel P|Bruno, Marco|Pan, Qiuwei|Smits, Ron
PMID: 30257989
Journal: Oncotarget. 2018 Sep 21;9(74):33982-33994.
Title: Sulforaphane inhibits growth and blocks Wnt/beta-catenin signaling of colorectal cancer cells.
Author: Bernkopf, Dominic B|Daum, Gabriele|Bruckner, Martina|Behrens, Jurgen
PMID: 30338040
Journal: J Cell Mol Med. 2018 Oct 19.
Title: MiR-30-5p suppresses cell chemoresistance and stemness in colorectal cancer through USP22/Wnt/beta-catenin signaling axis.
Author: Jiang, Shixiong|Miao, Dazhuang|Wang, Muhong|Lv, Jiachen|Wang, Yihui|Tong, Jinxue
PMID: 30338942
Journal: Cancer Biomark. 2018 Oct 9. pii: CBM181703.
Title: NUP153 overexpression suppresses the proliferation of colorectal cancer by negatively regulating Wnt/beta-catenin signaling pathway and predicts good prognosis.
Author: Wu, Yibin|Fang, Guojiu|Wang, Xin|Wang, Huipeng|Chen, Wenjie|Li, Liang|Ye, Tao|Gong, Lifeng|Ke, Chongwei|Cai, Yuankun
PMID: 30347601