Primary Site >> Liver Cancer
Gene >> AXIN1
| 1. | |||||||||||
| Journal: | Nat Genet. 2000 Mar;24(3):245-50. | ||||||||||
| Title: | AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1. | ||||||||||
| Author: | Satoh, S|Daigo, Y|Furukawa, Y|Kato, T|Miwa, N|Nishiwaki, T|Kawasoe, T|Ishiguro, H|Fujita, M|Tokino, T|Sasaki, Y|Imaoka, S|Murata, M|Shimano, T|Yamaoka, Y|Nakamura, Y | ||||||||||
| PMID: | 10700176 | ||||||||||
| 2. | |||||||||||
| Journal: | Gastroenterology. 2001 Jun;120(7):1763-73. | ||||||||||
| Title: | Genetic alterations associated with hepatocellular carcinomas define distinct pathways of hepatocarcinogenesis. | ||||||||||
| Author: | Laurent-Puig, P|Legoix, P|Bluteau, O|Belghiti, J|Franco, D|Binot, F|Monges, G|Thomas, G|Bioulac-Sage, P|Zucman-Rossi, J | ||||||||||
| PMID: | 11375957 | ||||||||||
| 3. | |||||||||||
| Journal: | Oncogene. 2001 Aug 16;20(36):5062-6. | ||||||||||
| Title: | Identification of AXUD1, a novel human gene induced by AXIN1 and its reduced expression in human carcinomas of the lung, liver, colon and kidney. | ||||||||||
| Author: | Ishiguro, H|Tsunoda, T|Tanaka, T|Fujii, Y|Nakamura, Y|Furukawa, Y | ||||||||||
| PMID: | 11526492 | ||||||||||
| 4. | |||||||||||
| Journal: | Oncogene. 2002 Jul 18;21(31):4863-71. | ||||||||||
| Title: | Mutational spectrum of beta-catenin, AXIN1, and AXIN2 in hepatocellular carcinomas and hepatoblastomas. | ||||||||||
| Author: | Taniguchi, Ken|Roberts, Lewis R|Aderca, Ileana N|Dong, Xiangyang|Qian, Chiping|Murphy, Linda M|Nagorney, David M|Burgart, Lawrence J|Roche, Patrick C|Smith, David I|Ross, Julie A|Liu, Wanguo | ||||||||||
| PMID: | 12101426 | ||||||||||
| 5. | |||||||||||
| Journal: | Oncogene. 2002 Nov 14;21(52):7971-80. | ||||||||||
| Title: | P53 mutation as a source of aberrant beta-catenin accumulation in cancer cells. | ||||||||||
| Author: | Cagatay, Tolga|Ozturk, Mehmet | ||||||||||
| PMID: | 12439747 | ||||||||||
| 6. | |||||||||||
| Journal: | Digestion. 2002;66(3):131-44. | ||||||||||
| Title: | Wnt/beta-catenin/tcf signaling: a critical pathway in gastrointestinal tumorigenesis. | ||||||||||
| Author: | Kolligs, Frank T|Bommer, Guido|Goke, Burkhard | ||||||||||
| PMID: | 12481159 | ||||||||||
| 7. | |||||||||||
| Journal: | Hepatology. 2003 Apr;37(4):852-61. | ||||||||||
| Title: | Homozygous deletion scanning in hepatobiliary tumor cell lines reveals alternative pathways for liver carcinogenesis. | ||||||||||
| Author: | Pineau, Pascal|Marchio, Agnes|Nagamori, Seishi|Seki, Shuichi|Tiollais, Pierre|Dejean, Anne | ||||||||||
| PMID: | 12668978 | ||||||||||
| 8. | |||||||||||
| Journal: | Int J Oncol. 2004 May;24(5):1077-83. | ||||||||||
| Title: | Immunohistochemical analysis and mutational analyses of beta-catenin, Axin family and APC genes in hepatocellular carcinomas. | ||||||||||
| Author: | Ishizaki, Yasuyo|Ikeda, Satoshi|Fujimori, Masahiko|Shimizu, Yosuke|Kurihara, Takeshi|Itamoto, Toshiyuki|Kikuchi, Akira|Okajima, Masazumi|Asahara, Toshimasa | ||||||||||
| PMID: | 15067328 | ||||||||||
| 9. | |||||||||||
| Journal: | Int J Cancer. 2005 Jul 20;115(6):903-10. | ||||||||||
| Title: | Lithium-mediated downregulation of PKB/Akt and cyclin E with growth inhibition in hepatocellular carcinoma cells. | ||||||||||
| Author: | Erdal, Esra|Ozturk, Nuri|Cagatay, Tolga|Eksioglu-Demiralp, Emel|Ozturk, Mehmet | ||||||||||
| PMID: | 15723355 | ||||||||||
| 10. | |||||||||||
| Journal: | Oncogene. 2007 Feb 1;26(5):774-80. | ||||||||||
| Title: | Differential effects of inactivated Axin1 and activated beta-catenin mutations in human hepatocellular carcinomas. | ||||||||||
| Author: | Zucman-Rossi, J|Benhamouche, S|Godard, C|Boyault, S|Grimber, G|Balabaud, C|Cunha, A S|Bioulac-Sage, P|Perret, C | ||||||||||
| PMID: | 16964294 | ||||||||||
| 11. | |||||||||||
| Journal: | J Gastroenterol Hepatol. 2008 Jan;23(1):110-8. | ||||||||||
| Title: | Genetic alterations of Wnt signaling pathway-associated genes in hepatocellular carcinoma. | ||||||||||
| Author: | Kim, Young-Dae|Park, Chang-Hwan|Kim, Hyun-Soo|Choi, Sung-Kyu|Rew, Jong-Sun|Kim, Dong-Yi|Koh, Yang-Suk|Jeung, Kyung-Woon|Lee, Kyung-Hwa|Lee, Ji-Shin|Juhng, Sang-Woo|Lee, Jae-Hyuk | ||||||||||
| PMID: | 18171349 | ||||||||||
| 12. | |||||||||||
| Journal: | J Gastroenterol. 2008;43(5):378-89. | ||||||||||
| Title: | Frequent epigenetic inactivation of SFRP genes in hepatocellular carcinoma. | ||||||||||
| Author: | Takagi, Hideyasu|Sasaki, Shigeru|Suzuki, Hiromu|Toyota, Minoru|Maruyama, Reo|Nojima, Masanori|Yamamoto, Hiroyuki|Omata, Masao|Tokino, Takashi|Imai, Kohzoh|Shinomura, Yasuhisa | ||||||||||
| PMID: | 18592156 | ||||||||||
| 13. | |||||||||||
| Journal: | Eur Urol. 2009 Sep;56(3):486-94. | ||||||||||
| Title: | Mutations in the AXIN1 gene in advanced prostate cancer. | ||||||||||
| Author: | Yardy, George W|Bicknell, David C|Wilding, Jennifer L|Bartlett, Sylvia|Liu, Ying|Winney, Bruce|Turner, Gareth D H|Brewster, Simon F|Bodmer, Walter F | ||||||||||
| PMID: | 18514389 | ||||||||||
| 14. | |||||||||||
| Journal: | Semin Cancer Biol. 2011 Feb;21(1):44-58. | ||||||||||
| Title: | Beta-catenin signaling, liver regeneration and hepatocellular cancer: sorting the good from the bad. | ||||||||||
| Author: | Nejak-Bowen, Kari Nichole|Monga, Satdarshan P S | ||||||||||
| PMID: | 21182948 | ||||||||||
| 15. | |||||||||||
| Journal: | Nat Genet. 2012 May 6;44(6):694-8. | ||||||||||
| Title: | Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma. | ||||||||||
| Author: | Guichard, Cecile|Amaddeo, Giuliana|Imbeaud, Sandrine|Ladeiro, Yannick|Pelletier, Laura|Maad, Ichrafe Ben|Calderaro, Julien|Bioulac-Sage, Paulette|Letexier, Melanie|Degos, Francoise|Clement, Bruno|Balabaud, Charles|Chevet, Eric|Laurent, Alexis|Couchy, Gabr | ||||||||||
| PMID: | 22561517 | ||||||||||
| 16. | |||||||||||
| Journal: | PLoS One. 2012;7(6):e39668. | ||||||||||
| Title: | Kruppel-like factor 8 is a new Wnt/beta-catenin signaling target gene and regulator in hepatocellular carcinoma. | ||||||||||
| Author: | Yang, Tian|Cai, Sheng-Yun|Zhang, Jin|Lu, Jun-Hua|Lin, Chuan|Zhai, Jian|Wu, Meng-Chao|Shen, Feng | ||||||||||
| PMID: | 22761862 | ||||||||||
| 17. | |||||||||||
| Journal: | N Biotechnol. 2013 May 25;30(4):381-4. | ||||||||||
| Title: | Genetics and epigenetics of liver cancer. | ||||||||||
| Author: | Ozen, Cigdem|Yildiz, Gokhan|Dagcan, Alper Tunga|Cevik, Dilek|Ors, Aysegul|Keles, Umur|Topel, Hande|Ozturk, Mehmet | ||||||||||
| PMID: | 23392071 | ||||||||||
| 18. | |||||||||||
| Journal: | Mutat Res. 2013 Aug 15;755(2):90-9. | ||||||||||
| Title: | Somatic changes in primary liver cancer in Russia: a pilot study. | ||||||||||
| Author: | Kalinina, Olga|Marchio, Agnes|Urbanskii, Aleksandr I|Tarkova, Aleksandra B|Rebbani, Khadija|Granov, Dmitri A|Dejean, Anne|Generalov, Mikhail I|Pineau, Pascal | ||||||||||
| PMID: | 23830926 | ||||||||||
| 19. | |||||||||||
| Journal: | Oncol Res. 2013;20(7):281-8. | ||||||||||
| Title: | Alterations of axis inhibition protein 1 (AXIN1) in hepatitis B virus-related hepatocellular carcinoma and overexpression of AXIN1 induces apoptosis in hepatocellular cancer cells. | ||||||||||
| Author: | Li, Jiequn|Quan, Hu|Liu, Qiang|Si, Zhongzhou|He, Zhijun|Qi, Haizhi | ||||||||||
| PMID: | 23879168 | ||||||||||
| 20. | |||||||||||
| Journal: | World J Gastroenterol. 2013 Dec 21;19(47):8873-9. | ||||||||||
| Title: | Target genes discovery through copy number alteration analysis in human hepatocellular carcinoma. | ||||||||||
| Author: | Gu, De-Leung|Chen, Yen-Hsieh|Shih, Jou-Ho|Lin, Chi-Hung|Jou, Yuh-Shan|Chen, Chian-Feng | ||||||||||
| PMID: | 24379610 | ||||||||||
| 21. | |||||||||||
| Journal: | PLoS One. 2014 Dec 19;9(12):e114263. | ||||||||||
| Title: | Integrated analysis of whole genome and transcriptome sequencing reveals diverse transcriptomic aberrations driven by somatic genomic changes in liver cancers. | ||||||||||
| Author: | Shiraishi, Yuichi|Fujimoto, Akihiro|Furuta, Mayuko|Tanaka, Hiroko|Chiba, Ken-ichi|Boroevich, Keith A|Abe, Tetsuo|Kawakami, Yoshiiku|Ueno, Masaki|Gotoh, Kunihito|Ariizumi, Shun-ichi|Shibuya, Tetsuo|Nakano, Kaoru|Sasaki, Aya|Maejima, Kazuhiro|Kitada, Rina|H | ||||||||||
| PMID: | 25526364 | ||||||||||
| 22. | |||||||||||
| Journal: | Genome Biol. 2014 Aug 26;15(8):436. | ||||||||||
| Title: | Diverse modes of genomic alteration in hepatocellular carcinoma. | ||||||||||
| Author: | Jhunjhunwala, Suchit|Jiang, Zhaoshi|Stawiski, Eric W|Gnad, Florian|Liu, Jinfeng|Mayba, Oleg|Du, Pan|Diao, Jingyu|Johnson, Stephanie|Wong, Kwong-Fai|Gao, Zhibo|Li, Yingrui|Wu, Thomas D|Kapadia, Sharookh B|Modrusan, Zora|French, Dorothy M|Luk, John M|Seshag | ||||||||||
| PMID: | 25159915 | ||||||||||
| 23. | |||||||||||
| Journal: | Hepatology. 2014 Dec;60(6):1972-82. | ||||||||||
| Title: | Genomic portrait of resectable hepatocellular carcinomas: implications of RB1 and FGF19 aberrations for patient stratification. | ||||||||||
| Author: | Ahn, Sung-Min|Jang, Se Jin|Shim, Ju Hyun|Kim, Deokhoon|Hong, Seung-Mo|Sung, Chang Ohk|Baek, Daehyun|Haq, Farhan|Ansari, Adnan Ahmad|Lee, Sun Young|Chun, Sung-Min|Choi, Seongmin|Choi, Hyun-Jeung|Kim, Jongkyu|Kim, Sukjun|Hwang, Shin|Lee, Young-Joo|Lee, Jong | ||||||||||
| PMID: | 24798001 | ||||||||||
| 24. | |||||||||||
| Journal: | PLoS One. 2014 Dec 11;9(12):e114912. | ||||||||||
| Title: | A peculiar mutation spectrum emerging from young peruvian patients with hepatocellular carcinoma. | ||||||||||
| Author: | Marchio, Agnes|Bertani, Stephane|Rojas Rojas, Teresa|Doimi, Franco|Terris, Benoit|Deharo, Eric|Dejean, Anne|Ruiz, Eloy|Pineau, Pascal | ||||||||||
| PMID: | 25502816 | ||||||||||
| 25. | |||||||||||
| Journal: | Gut. 2015 May;64(5):820-9. | ||||||||||
| Title: | Integration of tumour and viral genomic characterizations in HBV-related hepatocellular carcinomas. | ||||||||||
| Author: | Amaddeo, Giuliana|Cao, Qian|Ladeiro, Yannick|Imbeaud, Sandrine|Nault, Jean-Charles|Jaoui, Daphne|Gaston Mathe, Yann|Laurent, Christophe|Laurent, Alexis|Bioulac-Sage, Paulette|Calderaro, Julien|Zucman-Rossi, Jessica | ||||||||||
| PMID: | 25021421 | ||||||||||
| 26. | |||||||||||
| Journal: | Nat Genet. 2015 May;47(5):505-511. | ||||||||||
| Title: | Exome sequencing of hepatocellular carcinomas identifies new mutational signatures and potential therapeutic targets. | ||||||||||
| Author: | Schulze, Kornelius|Imbeaud, Sandrine|Letouze, Eric|Alexandrov, Ludmil B|Calderaro, Julien|Rebouissou, Sandra|Couchy, Gabrielle|Meiller, Clement|Shinde, Jayendra|Soysouvanh, Frederic|Calatayud, Anna-Line|Pinyol, Roser|Pelletier, Laura|Balabaud, Charles|Lau | ||||||||||
| PMID: | 25822088 | ||||||||||
| 27. | |||||||||||
| Journal: | World J Gastroenterol. 2015 May 28;21(20):6317-28. | ||||||||||
| Title: | Integrative analysis of aberrant Wnt signaling in hepatitis B virus-related hepatocellular carcinoma. | ||||||||||
| Author: | Ding, Shan-Long|Yang, Zi-Wei|Wang, Jie|Zhang, Xiao-Lei|Chen, Xiang-Mei|Lu, Feng-Min | ||||||||||
| PMID: | 26034368 | ||||||||||
| 28. | |||||||||||
| Journal: | Gastroenterology. 2015 Oct;149(5):1226-1239.e4. | ||||||||||
| Title: | Genetic Landscape and Biomarkers of Hepatocellular Carcinoma. | ||||||||||
| Author: | Zucman-Rossi, Jessica|Villanueva, Augusto|Nault, Jean-Charles|Llovet, Josep M | ||||||||||
| PMID: | 26099527 | ||||||||||
| 29. | |||||||||||
| Journal: | Oncotarget. 2015 Sep 22;6(28):25390-401. | ||||||||||
| Title: | Tankyrase inhibitors attenuate WNT/beta-catenin signaling and inhibit growth of hepatocellular carcinoma cells. | ||||||||||
| Author: | Ma, Li|Wang, Xiaolin|Jia, Tao|Wei, Wei|Chua, Mei-Sze|So, Samuel | ||||||||||
| PMID: | 26246473 | ||||||||||
| 30. | |||||||||||
| Journal: | Neoplasia. 2016 Dec;18(12):711-723. | ||||||||||
| Title: | Blocking Wnt Secretion Reduces Growth of Hepatocellular Carcinoma Cell Lines Mostly Independent of beta-Catenin Signaling. | ||||||||||
| Author: | Wang, Wenhui|Xu, Lei|Liu, Pengyu|Jairam, Kiran|Yin, Yuebang|Chen, Kan|Sprengers, Dave|Peppelenbosch, Maikel P|Pan, Qiuwei|Smits, Ron | ||||||||||
| PMID: | 27851986 | ||||||||||
| 31. | |||||||||||
| Journal: | Clin Biochem. 2016 Jul;49(10-11):792-801. | ||||||||||
| Title: | Genetic polymorphisms in the Wnt/beta-catenin pathway genes as predictors of tumor development and survival in patients with hepatitis B virus-associated hepatocellular carcinoma. | ||||||||||
| Author: | Kim, Soon Sun|Cho, Hyo Jung|Lee, Hyun-Young|Park, Ju Han|Noh, Choong Kyun|Shin, Sung Jae|Lee, Kee Myung|Yoo, Byung Moo|Lee, Kwang Jae|Cho, Sung Won|Cheong, Jae Youn | ||||||||||
| PMID: | 26968103 | ||||||||||
| 32. | |||||||||||
| Journal: | J Gastroenterol. 2016 May;51(5):473-86. | ||||||||||
| Title: | Comprehensive analyses of mutations and hepatitis B virus integration in hepatocellular carcinoma with clinicopathological features. | ||||||||||
| Author: | Kawai-Kitahata, Fukiko|Asahina, Yasuhiro|Tanaka, Shinji|Kakinuma, Sei|Murakawa, Miyako|Nitta, Sayuri|Watanabe, Takako|Otani, Satoshi|Taniguchi, Miki|Goto, Fumio|Nagata, Hiroko|Kaneko, Shun|Tasaka-Fujita, Megumi|Nishimura-Sakurai, Yuki|Azuma, Seishin|Itsui | ||||||||||
| PMID: | 26553052 | ||||||||||
| 33. | |||||||||||
| Journal: | Mol Oncol. 2016 Feb;10(2):195-212. | ||||||||||
| Title: | 5-Hydroxytryptamine promotes hepatocellular carcinoma proliferation by influencing beta-catenin. | ||||||||||
| Author: | Fatima, Sarwat|Shi, Xiaoke|Lin, Zesi|Chen, Guo-qing|Pan, Xiao-hua|Wu, Justin Che-Yuen|Ho, John W|Lee, Nikki P|Gao, Hengjun|Zhang, Ge|Lu, Aiping|Bian, Zhao Xiang | ||||||||||
| PMID: | 26474915 | ||||||||||
| 34. | |||||||||||
| Journal: | Carcinogenesis. 2017 Jan;38(1):2-11. | ||||||||||
| Title: | Frequently mutated genes/pathways and genomic instability as prevention targets in liver cancer. | ||||||||||
| Author: | Rao, Chinthalapally V|Asch, Adam S|Yamada, Hiroshi Y | ||||||||||
| PMID: | 27838634 | ||||||||||
| 35. | |||||||||||
| Journal: | Int J Mol Med. 2017 Feb;39(2):347-356. | ||||||||||
| Title: | The role of lncRNA MALAT1 in the regulation of hepatocyte proliferation during liver regeneration. | ||||||||||
| Author: | Li, Cuicui|Chang, Lei|Chen, Zhiquan|Liu, Zhongzhong|Wang, Yanfeng|Ye, Qifa | ||||||||||
| PMID: | 28075444 | ||||||||||
| 36. | |||||||||||
| Journal: | Int J Oncol. 2017 Aug;51(2):545-554. | ||||||||||
| Title: | The Wnt inhibitor LGK-974 enhances radiosensitivity of HepG2 cells by modulating Nrf2 signaling. | ||||||||||
| Author: | Tian, Dan|Shi, Ying|Chen, Dexi|Liu, Qiang|Fan, Feiyue | ||||||||||
| PMID: | 28627706 | ||||||||||
| 37. | |||||||||||
| Journal: | J Cell Sci. 2017 Sep 15;130(18):3108-3115. | ||||||||||
| Title: | TRIM65 triggers beta-catenin signaling via ubiquitylation of Axin1 to promote hepatocellular carcinoma. | ||||||||||
| Author: | Yang, Yu-Feng|Zhang, Mei-Fang|Tian, Qiu-Hong|Zhang, Chris Zhiyi | ||||||||||
| PMID: | 28754688 | ||||||||||
| 38. | |||||||||||
| Journal: | Mol Cancer. 2017 Aug 30;16(1):149. | ||||||||||
| Title: | The biology of Hepatocellular carcinoma: implications for genomic and immune therapies. | ||||||||||
| Author: | Khemlina, Galina|Ikeda, Sadakatsu|Kurzrock, Razelle | ||||||||||
| PMID: | 28854942 | ||||||||||
| 39. | |||||||||||
| Journal: | J Hepatol. 2018 Jun;68(6):1203-1213. | ||||||||||
| Title: | AXIN deficiency in human and mouse hepatocytes induces hepatocellular carcinoma in the absence of beta-catenin activation. | ||||||||||
| Author: | Abitbol, Shirley|Dahmani, Rajae|Coulouarn, Cedric|Ragazzon, Bruno|Mlecnik, Bernhard|Senni, Nadia|Savall, Mathilde|Bossard, Pascale|Sohier, Pierre|Drouet, Valerie|Tournier, Emilie|Dumont, Florent|Sanson, Romain|Calderaro, Julien|Zucman-Rossi, Jessica|Vasse | ||||||||||
| PMID: | 29525529 | ||||||||||
| 40. | |||||||||||
| Journal: | Int J Mol Med. 2018 Aug;42(2):713-725. | ||||||||||
| Title: | Multilayered prevention and treatment of chronic inflammation, organ fibrosis and cancer associated with canonical WNT/betacatenin signaling activation (Review). | ||||||||||
| Author: | Katoh, Masaru | ||||||||||
| PMID: | 29786110 | ||||||||||
| 41. | |||||||||||
| Journal: | Clin Cancer Res. 2018 Sep 21. pii: 1078-0432.CCR-18-0088. | ||||||||||
| Title: | Multi-modal meta-analysis of 1494 hepatocellular carcinoma samples reveals significant impact of consensus driver genes on phenotypes. | ||||||||||
| Author: | Chaudhary, Kumardeep|Poirion, Olivier B|Lu, Liangqun|Huang, Sijia|Ching, Travers|Garmire, Lana X | ||||||||||
| PMID: | 30242023 | ||||||||||
| 42. | |||||||||||
| Journal: | Mol Cancer Res. 2018 Sep 26. pii: 1541-7786.MCR-18-0054. | ||||||||||
| Title: | Oncogenic STRAP Supports Hepatocellular Carcinoma Growth by Enhancing Wnt/beta-Catenin Signaling. | ||||||||||
| Author: | Wang, Wenhui|Li, Shan|Liu, Pengyu|Sideras, Kostandinos|van de Werken, Harmen J G|van der Heide, Marieke|Cao, Wanlu|Lavrijsen, Marla|Peppelenbosch, Maikel P|Bruno, Marco|Pan, Qiuwei|Smits, Ron | ||||||||||
| PMID: | 30257989 | ||||||||||