Primary Site >> Colorectal Cancer
Gene >> AXIN1
| 1. | |||||||||||
| Journal: | Proc Natl Acad Sci U S A. 1998 Mar 17;95(6):3020-3. | ||||||||||
| Title: | Bridging of beta-catenin and glycogen synthase kinase-3beta by axin and inhibition of beta-catenin-mediated transcription. | ||||||||||
| Author: | Sakanaka, C|Weiss, J B|Williams, L T | ||||||||||
| PMID: | 9501208 | ||||||||||
| 2. | |||||||||||
| Journal: | Curr Biol. 1998 May 7;8(10):573-81. | ||||||||||
| Title: | Downregulation of beta-catenin by human Axin and its association with the APC tumor suppressor, beta-catenin and GSK3 beta. | ||||||||||
| Author: | Hart, M J|de los Santos, R|Albert, I N|Rubinfeld, B|Polakis, P | ||||||||||
| PMID: | 9601641 | ||||||||||
| 3. | |||||||||||
| Journal: | Genes Cells. 1998 Jun;3(6):395-403. | ||||||||||
| Title: | Axin, an inhibitor of the Wnt signalling pathway, interacts with beta-catenin, GSK-3beta and APC and reduces the beta-catenin level. | ||||||||||
| Author: | Nakamura, T|Hamada, F|Ishidate, T|Anai, K|Kawahara, K|Toyoshima, K|Akiyama, T | ||||||||||
| PMID: | 9734785 | ||||||||||
| 4. | |||||||||||
| Journal: | Curr Biol. 1999 Jan 28;9(2):105-8. | ||||||||||
| Title: | Identification of APC2, a homologue of the adenomatous polyposis coli tumour suppressor. | ||||||||||
| Author: | van Es, J H|Kirkpatrick, C|van de Wetering, M|Molenaar, M|Miles, A|Kuipers, J|Destree, O|Peifer, M|Clevers, H | ||||||||||
| PMID: | 10021369 | ||||||||||
| 5. | |||||||||||
| Journal: | EMBO J. 1999 May 4;18(9):2401-10. | ||||||||||
| Title: | An F-box protein, FWD1, mediates ubiquitin-dependent proteolysis of beta-catenin. | ||||||||||
| Author: | Kitagawa, M|Hatakeyama, S|Shirane, M|Matsumoto, M|Ishida, N|Hattori, K|Nakamichi, I|Kikuchi, A|Nakayama, K|Nakayama, K | ||||||||||
| PMID: | 10228155 | ||||||||||
| 6. | |||||||||||
| Journal: | Proc Natl Acad Sci U S A. 1999 May 11;96(10):5522-7. | ||||||||||
| Title: | The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway. | ||||||||||
| Author: | Shtutman, M|Zhurinsky, J|Simcha, I|Albanese, C|D'Amico, M|Pestell, R|Ben-Ze'ev, A | ||||||||||
| PMID: | 10318916 | ||||||||||
| 7. | |||||||||||
| Journal: | Bioessays. 1999 Dec;21(12):1021-30. | ||||||||||
| Title: | beta-catenin signaling and cancer. | ||||||||||
| Author: | Morin, P J | ||||||||||
| PMID: | 10580987 | ||||||||||
| 8. | |||||||||||
| Journal: | Nat Genet. 2000 Mar;24(3):245-50. | ||||||||||
| Title: | AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1. | ||||||||||
| Author: | Satoh, S|Daigo, Y|Furukawa, Y|Kato, T|Miwa, N|Nishiwaki, T|Kawasoe, T|Ishiguro, H|Fujita, M|Tokino, T|Sasaki, Y|Imaoka, S|Murata, M|Shimano, T|Yamaoka, Y|Nakamura, Y | ||||||||||
| PMID: | 10700176 | ||||||||||
| 9. | |||||||||||
| Journal: | J Biol Chem. 2000 Mar 24;275(12):8369-74. | ||||||||||
| Title: | Down-regulation of beta-catenin by the colorectal tumor suppressor APC requires association with Axin and beta-catenin. | ||||||||||
| Author: | Kawahara, K|Morishita, T|Nakamura, T|Hamada, F|Toyoshima, K|Akiyama, T | ||||||||||
| PMID: | 10722668 | ||||||||||
| 10. | |||||||||||
| Journal: | Genes Chromosomes Cancer. 2000 Aug;28(4):443-53. | ||||||||||
| Title: | Sequence variants of the axin gene in breast, colon, and other cancers: an analysis of mutations that interfere with GSK3 binding. | ||||||||||
| Author: | Webster, M T|Rozycka, M|Sara, E|Davis, E|Smalley, M|Young, N|Dale, T C|Wooster, R | ||||||||||
| PMID: | 10862053 | ||||||||||
| 11. | |||||||||||
| Journal: | J Biol Chem. 2000 Nov 3;275(44):34399-406. | ||||||||||
| Title: | Complex formation of adenomatous polyposis coli gene product and axin facilitates glycogen synthase kinase-3 beta-dependent phosphorylation of beta-catenin and down-regulates beta-catenin. | ||||||||||
| Author: | Hinoi, T|Yamamoto, H|Kishida, M|Takada, S|Kishida, S|Kikuchi, A | ||||||||||
| PMID: | 10906131 | ||||||||||
| 12. | |||||||||||
| Journal: | Oncol Res. 2000;12(4):193-201. | ||||||||||
| Title: | Sodium butyrate-induced differentiation of human LIM2537 colon cancer cells decreases GSK-3beta activity and increases levels of both membrane-bound and Apc/axin/GSK-3beta complex-associated pools of beta-catenin. | ||||||||||
| Author: | Vincan, E|Leet, C S|Reyes, N I|Dilley, R J|Thomas, R J|Phillips, W A | ||||||||||
| PMID: | 11341469 | ||||||||||
| 13. | |||||||||||
| Journal: | Mol Carcinog. 2001 May;31(1):56-62. | ||||||||||
| Title: | Wingless-type frizzled protein receptor signaling and its putative role in human colon cancer. | ||||||||||
| Author: | Uthoff, S M|Eichenberger, M R|McAuliffe, T L|Hamilton, C J|Galandiuk, S | ||||||||||
| PMID: | 11398198 | ||||||||||
| 14. | |||||||||||
| Journal: | Oncogene. 2001 Aug 16;20(36):5062-6. | ||||||||||
| Title: | Identification of AXUD1, a novel human gene induced by AXIN1 and its reduced expression in human carcinomas of the lung, liver, colon and kidney. | ||||||||||
| Author: | Ishiguro, H|Tsunoda, T|Tanaka, T|Fujii, Y|Nakamura, Y|Furukawa, Y | ||||||||||
| PMID: | 11526492 | ||||||||||
| 15. | |||||||||||
| Journal: | Cancer Res. 2001 Nov 1;61(21):7722-6. | ||||||||||
| Title: | Up-regulation of the ectodermal-neural cortex 1 (ENC1) gene, a downstream target of the beta-catenin/T-cell factor complex, in colorectal carcinomas. | ||||||||||
| Author: | Fujita, M|Furukawa, Y|Tsunoda, T|Tanaka, T|Ogawa, M|Nakamura, Y | ||||||||||
| PMID: | 11691783 | ||||||||||
| 16. | |||||||||||
| Journal: | Genes Chromosomes Cancer. 2002 Jan;33(1):73-81. | ||||||||||
| Title: | Frequent alterations in the Wnt signaling pathway in colorectal cancer with microsatellite instability. | ||||||||||
| Author: | Shimizu, Yosuke|Ikeda, Satoshi|Fujimori, Masahiko|Kodama, Shinya|Nakahara, Masahiro|Okajima, Masazumi|Asahara, Toshimasa | ||||||||||
| PMID: | 11746989 | ||||||||||
| 17. | |||||||||||
| Journal: | Mol Cell Biol. 2002 Feb;22(4):1184-93. | ||||||||||
| Title: | Negative feedback loop of Wnt signaling through upregulation of conductin/axin2 in colorectal and liver tumors. | ||||||||||
| Author: | Lustig, Barbara|Jerchow, Boris|Sachs, Martin|Weiler, Sigrid|Pietsch, Torsten|Karsten, Uwe|van de Wetering, Marc|Clevers, Hans|Schlag, Peter M|Birchmeier, Walter|Behrens, Jurgen | ||||||||||
| PMID: | 11809809 | ||||||||||
| 18. | |||||||||||
| Journal: | Am J Pathol. 2002 Feb;160(2):389-401. | ||||||||||
| Title: | Beta-catenin--a linchpin in colorectal carcinogenesis? | ||||||||||
| Author: | Wong, Newton Alexander Chiang Shuek|Pignatelli, Massimo | ||||||||||
| PMID: | 11839557 | ||||||||||
| 19. | |||||||||||
| Journal: | Biol Chem. 2002 Feb;383(2):255-61. | ||||||||||
| Title: | TCF: Lady Justice casting the final verdict on the outcome of Wnt signalling. | ||||||||||
| Author: | Brantjes, Helen|Barker, Nick|van Es, Johan|Clevers, Hans | ||||||||||
| PMID: | 11934263 | ||||||||||
| 20. | |||||||||||
| Journal: | Am J Pathol. 2002 Apr;160(4):1229-38. | ||||||||||
| Title: | Role of beta-catenin/T-cell factor-regulated genes in ovarian endometrioid adenocarcinomas. | ||||||||||
| Author: | Zhai, Yali|Wu, Rong|Schwartz, Donald R|Darrah, Danielle|Reed, Heather|Kolligs, Frank T|Nieman, Marvin T|Fearon, Eric R|Cho, Kathleen R | ||||||||||
| PMID: | 11943708 | ||||||||||
| 21. | |||||||||||
| Journal: | J Biol Chem. 2002 Jul 5;277(27):24258-64. Epub 2002 May 1. | ||||||||||
| Title: | Lymphoid enhancer factor-1 blocks adenomatous polyposis coli-mediated nuclear export and degradation of beta-catenin. Regulation by histone deacetylase 1. | ||||||||||
| Author: | Henderson, Beric R|Galea, Melanie|Schuechner, Stefan|Leung, Louie | ||||||||||
| PMID: | 11986304 | ||||||||||
| 22. | |||||||||||
| Journal: | Cancer Res. 2002 Jun 1;62(11):3322-6. | ||||||||||
| Title: | Overexpression of Icat induces G(2) arrest and cell death in tumor cell mutants for adenomatous polyposis coli, beta-catenin, or Axin. | ||||||||||
| Author: | Sekiya, Takashi|Nakamura, Tsutomu|Kazuki, Yasuhiro|Oshimura, Mitsuo|Kohu, Kazuyoshi|Tago, Ken-Ichi|Ohwada, Susumu|Akiyama, Tetsu | ||||||||||
| PMID: | 12036951 | ||||||||||
| 23. | |||||||||||
| Journal: | Proc Natl Acad Sci U S A. 2002 Jun 25;99(13):8683-8. Epub 2002 Jun 18. | ||||||||||
| Title: | Subcellular distribution of Wnt pathway proteins in normal and neoplastic colon. | ||||||||||
| Author: | Anderson, Christine B|Neufeld, Kristi L|White, Raymond L | ||||||||||
| PMID: | 12072559 | ||||||||||
| 24. | |||||||||||
| Journal: | Cancer Res. 2002 Oct 15;62(20):5651-6. | ||||||||||
| Title: | Isolation of a novel human gene, APCDD1, as a direct target of the beta-Catenin/T-cell factor 4 complex with probable involvement in colorectal carcinogenesis. | ||||||||||
| Author: | Takahashi, Meiko|Fujita, Manabu|Furukawa, Yoichi|Hamamoto, Ryuji|Shimokawa, Takashi|Miwa, Nobutomo|Ogawa, Michio|Nakamura, Yusuke | ||||||||||
| PMID: | 12384519 | ||||||||||
| 25. | |||||||||||
| Journal: | Digestion. 2002;66(3):131-44. | ||||||||||
| Title: | Wnt/beta-catenin/tcf signaling: a critical pathway in gastrointestinal tumorigenesis. | ||||||||||
| Author: | Kolligs, Frank T|Bommer, Guido|Goke, Burkhard | ||||||||||
| PMID: | 12481159 | ||||||||||
| 26. | |||||||||||
| Journal: | Cancer Biol Ther. 2002 Nov-Dec;1(6):621-5. | ||||||||||
| Title: | beta-Catenin signaling: therapeutic strategies in oncology. | ||||||||||
| Author: | Li, Han|Pamukcu, Rifat|Thompson, W Joseph | ||||||||||
| PMID: | 12642683 | ||||||||||
| 27. | |||||||||||
| Journal: | Oncogene. 2003 Jan 30;22(4):632-6. | ||||||||||
| Title: | AXIN1 mutations but not deletions in cerebellar medulloblastomas. | ||||||||||
| Author: | Baeza, Nathalie|Masuoka, Jun|Kleihues, Paul|Ohgaki, Hiroko | ||||||||||
| PMID: | 12555076 | ||||||||||
| 28. | |||||||||||
| Journal: | Int J Cancer. 2003 Dec 10;107(5):696-9. | ||||||||||
| Title: | Detection of point mutations of the Axin1 gene in colorectal cancers. | ||||||||||
| Author: | Jin, Li-Hua|Shao, Qiu-Jie|Luo, Wen|Ye, Zhi-Yun|Li, Qing|Lin, Sheng-Cai | ||||||||||
| PMID: | 14566817 | ||||||||||
| 29. | |||||||||||
| Journal: | Med Klin (Munich). 2003 Dec 15;98(12):776-82. | ||||||||||
| Title: | [Familial adenomatous polyposis syndrome (FAP): pathogenesis and molecular mechanisms]. | ||||||||||
| Author: | Friedrich, Anja|Kullmann, Frank | ||||||||||
| PMID: | 14685680 | ||||||||||
| 30. | |||||||||||
| Journal: | Oncol Rep. 2004 Feb;11(2):341-8. | ||||||||||
| Title: | Promoter CpG methylation of tumor suppressor genes in colorectal cancer and its relationship to clinical features. | ||||||||||
| Author: | Lin, Shyr-Yi|Yeh, Kun-Tu|Chen, Willian Tzu-Liang|Chen, Hung-Chang|Chen, Shou-Tung|Chiou, Hung-Yi|Chang, Jan-Gowth | ||||||||||
| PMID: | 14719065 | ||||||||||
| 31. | |||||||||||
| Journal: | Oncogene. 2004 Jun 3;23(26):4577-83. | ||||||||||
| Title: | Failure of a medulloblastoma-derived mutant of SUFU to suppress WNT signaling. | ||||||||||
| Author: | Taylor, Michael D|Zhang, Xiaoyun|Liu, Ling|Hui, Chi-Chung|Mainprize, Todd G|Scherer, Stephen W|Wainwright, Brandon|Hogg, David|Rutka, James T | ||||||||||
| PMID: | 15077159 | ||||||||||
| 32. | |||||||||||
| Journal: | Proc Natl Acad Sci U S A. 2004 Nov 9;101(45):15992-7. Epub 2004 Nov 1. | ||||||||||
| Title: | Multiple rare variants in different genes account for multifactorial inherited susceptibility to colorectal adenomas. | ||||||||||
| Author: | Fearnhead, Nicola S|Wilding, Jennifer L|Winney, Bruce|Tonks, Susan|Bartlett, Sylvia|Bicknell, David C|Tomlinson, Ian P M|Mortensen, Neil J McC|Bodmer, Walter F | ||||||||||
| PMID: | 15520370 | ||||||||||
| 33. | |||||||||||
| Journal: | Cancer Res. 2004 Dec 1;64(23):8496-501. | ||||||||||
| Title: | Role of a BCL9-related beta-catenin-binding protein, B9L, in tumorigenesis induced by aberrant activation of Wnt signaling. | ||||||||||
| Author: | Adachi, Shungo|Jigami, Takafumi|Yasui, Toshio|Nakano, Tetsuhiro|Ohwada, Susumu|Omori, Yoshihiro|Sugano, Sumio|Ohkawara, Bisei|Shibuya, Hiroshi|Nakamura, Tsutomu|Akiyama, Tetsu | ||||||||||
| PMID: | 15574752 | ||||||||||
| 34. | |||||||||||
| Journal: | Cancer Res. 2005 Jan 1;65(1):166-76. | ||||||||||
| Title: | Transcriptional profiles of intestinal tumors in Apc(Min) mice are unique from those of embryonic intestine and identify novel gene targets dysregulated in human colorectal tumors. | ||||||||||
| Author: | Reichling, Tim|Goss, Kathleen Heppner|Carson, Daniel J|Holdcraft, Robert W|Ley-Ebert, Cathy|Witte, Dave|Aronow, Bruce J|Groden, Joanna | ||||||||||
| PMID: | 15665292 | ||||||||||
| 35. | |||||||||||
| Journal: | Biochem Biophys Res Commun. 2005 Mar 4;328(1):227-34. | ||||||||||
| Title: | Quercetin, a potent inhibitor against beta-catenin/Tcf signaling in SW480 colon cancer cells. | ||||||||||
| Author: | Park, Chi Hoon|Chang, Joon Young|Hahm, Eun Ryeong|Park, Seyeon|Kim, Hyun-Kyung|Yang, Chul Hak | ||||||||||
| PMID: | 15670774 | ||||||||||
| 36. | |||||||||||
| Journal: | Gastroenterology. 2005 Jun;128(7):1907-18. | ||||||||||
| Title: | Oncogenic K-ras stimulates Wnt signaling in colon cancer through inhibition of GSK-3beta. | ||||||||||
| Author: | Li, Jingnan|Mizukami, Yusuke|Zhang, Xiaobo|Jo, Won-Seok|Chung, Daniel C | ||||||||||
| PMID: | 15940626 | ||||||||||
| 37. | |||||||||||
| Journal: | Anat Sci Int. 2005 Sep;80(3):121-31. | ||||||||||
| Title: | Adenomatous polyposis coli (Apc) tumor suppressor gene as a multifunctional gene. | ||||||||||
| Author: | Senda, Takao|Shimomura, Atsushi|Iizuka-Kogo, Akiko | ||||||||||
| PMID: | 16158975 | ||||||||||
| 38. | |||||||||||
| Journal: | Int J Oncol. 2005 Dec;27(6):1483-7. | ||||||||||
| Title: | Identification of SP5 as a downstream gene of the beta-catenin/Tcf pathway and its enhanced expression in human colon cancer. | ||||||||||
| Author: | Takahashi, Meiko|Nakamura, Yusuke|Obama, Kazutaka|Furukawa, Yoichi | ||||||||||
| PMID: | 16273202 | ||||||||||
| 39. | |||||||||||
| Journal: | Science. 2005 Dec 2;310(5753):1504-10. | ||||||||||
| Title: | Prostaglandin E2 promotes colon cancer cell growth through a Gs-axin-beta-catenin signaling axis. | ||||||||||
| Author: | Castellone, Maria Domenica|Teramoto, Hidemi|Williams, Bart O|Druey, Kirk M|Gutkind, J Silvio | ||||||||||
| PMID: | 16293724 | ||||||||||
| 40. | |||||||||||
| Journal: | BMC Genomics. 2006 Jun 13;7:148. | ||||||||||
| Title: | Verification of predicted alternatively spliced Wnt genes reveals two new splice variants (CTNNB1 and LRP5) and altered Axin-1 expression during tumour progression. | ||||||||||
| Author: | Pospisil, Heike|Herrmann, Alexander|Butherus, Kristine|Pirson, Stefan|Reich, Jens G|Kemmner, Wolfgang | ||||||||||
| PMID: | 16772034 | ||||||||||
| 41. | |||||||||||
| Journal: | Am J Gastroenterol. 2006 Dec;101(12):2810-7. | ||||||||||
| Title: | Singapore familial adenomatous polyposis (FAP) patients with classical adenomatous polyposis but undetectable APC mutations have accelerated cancer progression. | ||||||||||
| Author: | Cao, Xia|Hong, Yi|Eu, Kong Weng|Loi, Carol|Cheah, Peh Yean | ||||||||||
| PMID: | 17026565 | ||||||||||
| 42. | |||||||||||
| Journal: | Oncogene. 2006 Dec 4;25(57):7531-7. | ||||||||||
| Title: | Colorectal cancer and genetic alterations in the Wnt pathway. | ||||||||||
| Author: | Segditsas, S|Tomlinson, I | ||||||||||
| PMID: | 17143297 | ||||||||||
| 43. | |||||||||||
| Journal: | Oncogene. 2007 Jul 12;26(32):4699-713. Epub 2007 Feb 5. | ||||||||||
| Title: | Frequent epigenetic inactivation of SFRP genes and constitutive activation of Wnt signaling in gastric cancer. | ||||||||||
| Author: | Nojima, M|Suzuki, H|Toyota, M|Watanabe, Y|Maruyama, R|Sasaki, S|Sasaki, Y|Mita, H|Nishikawa, N|Yamaguchi, K|Hirata, K|Itoh, F|Tokino, T|Mori, M|Imai, K|Shinomura, Y | ||||||||||
| PMID: | 17297461 | ||||||||||
| 44. | |||||||||||
| Journal: | Proteins. 2007 Jun 1;67(4):941-9. | ||||||||||
| Title: | Insights into unbinding mechanisms upon two mutations investigated by molecular dynamics study of GSK3beta-axin complex: role of packing hydrophobic residues. | ||||||||||
| Author: | Zhang, Na|Jiang, Yongjun|Zou, Jianwei|Zhuang, Shulin|Jin, Haixiao|Yu, Qingsen | ||||||||||
| PMID: | 17380482 | ||||||||||
| 45. | |||||||||||
| Journal: | Science. 2007 May 18;316(5827):1043-6. | ||||||||||
| Title: | Wilms tumor suppressor WTX negatively regulates WNT/beta-catenin signaling. | ||||||||||
| Author: | Major, Michael B|Camp, Nathan D|Berndt, Jason D|Yi, Xianhua|Goldenberg, Seth J|Hubbert, Charlotte|Biechele, Travis L|Gingras, Anne-Claude|Zheng, Ning|Maccoss, Michael J|Angers, Stephane|Moon, Randall T | ||||||||||
| PMID: | 17510365 | ||||||||||
| 46. | |||||||||||
| Journal: | Int J Cancer. 2007 Sep 15;121(6):1175-81. | ||||||||||
| Title: | Inhibition of Wnt-2 and galectin-3 synergistically destabilizes beta-catenin and induces apoptosis in human colorectal cancer cells. | ||||||||||
| Author: | Shi, Yihui|He, Biao|Kuchenbecker, Kristopher M|You, Liang|Xu, Zhidong|Mikami, Iwao|Yagui-Beltran, Adam|Clement, Genevieve|Lin, Yu-Ching|Okamoto, Junichi|Bravo, Dawn T|Jablons, David M | ||||||||||
| PMID: | 17534895 | ||||||||||
| 47. | |||||||||||
| Journal: | Med Mol Morphol. 2007 Jun;40(2):68-81. Epub 2007 Jun 18. | ||||||||||
| Title: | Adenomatous polyposis coli (APC) plays multiple roles in the intestinal and colorectal epithelia. | ||||||||||
| Author: | Senda, Takao|Iizuka-Kogo, Akiko|Onouchi, Takanori|Shimomura, Atsushi | ||||||||||
| PMID: | 17572842 | ||||||||||
| 48. | |||||||||||
| Journal: | Cell Signal. 2007 Sep;19(9):1973-85. Epub 2007 Jun 2. | ||||||||||
| Title: | Htid-1, the human homolog of the Drosophila melanogaster l(2)tid tumor suppressor, defines a novel physiological role of APC. | ||||||||||
| Author: | Kurzik-Dumke, Ursula|Czaja, Joachim | ||||||||||
| PMID: | 17588722 | ||||||||||
| 49. | |||||||||||
| Journal: | J Cell Sci. 2007 Oct 1;120(Pt 19):3327-35. | ||||||||||
| Title: | Adenomatous polyposis coli (APC): a multi-functional tumor suppressor gene. | ||||||||||
| Author: | Aoki, Koji|Taketo, Makoto M | ||||||||||
| PMID: | 17881494 | ||||||||||
| 50. | |||||||||||
| Journal: | Genes Cells. 2007 Dec;12(12):1339-45. | ||||||||||
| Title: | Putative tumor suppressor EDD interacts with and up-regulates APC. | ||||||||||
| Author: | Ohshima, Ryuichi|Ohta, Tomohiko|Wu, Wenwen|Koike, Ayaka|Iwatani, Tsuguo|Henderson, Michelle|Watts, Colin K W|Otsubo, Takehito | ||||||||||
| PMID: | 18076571 | ||||||||||
| 51. | |||||||||||
| Journal: | Int J Mol Med. 2008 Jan;21(1):19-31. | ||||||||||
| Title: | Progression of colorectal cancers correlates with overexpression and loss of polarization of expression of the htid-1 tumor suppressor. | ||||||||||
| Author: | Kurzik-Dumke, Ursula|Horner, Manuela|Czaja, Joachim|Nicotra, Maria Rita|Simiantonaki, Nektaria|Koslowski, Michael|Natali, Pier Giorgio | ||||||||||
| PMID: | 18097612 | ||||||||||
| 52. | |||||||||||
| Journal: | Genes Chromosomes Cancer. 2008 Jul;47(7):614-24. | ||||||||||
| Title: | Concomitant activation of Wnt pathway and loss of mismatch repair function in human melanoma. | ||||||||||
| Author: | Castiglia, Daniele|Bernardini, Silvia|Alvino, Ester|Pagani, Elena|De Luca, Naomi|Falcinelli, Sabrina|Pacchiarotti, Alberto|Bonmassar, Enzo|Zambruno, Giovanna|D'Atri, Stefania | ||||||||||
| PMID: | 18384130 | ||||||||||
| 53. | |||||||||||
| Journal: | Oncol Res. 2008;17(1):1-9. | ||||||||||
| Title: | Hyperinduction of Wnt activity: a new paradigm for the treatment of colorectal cancer? | ||||||||||
| Author: | Bordonaro, Michael|Lazarova, Darina L|Sartorelli, Alan C | ||||||||||
| PMID: | 18488710 | ||||||||||
| 54. | |||||||||||
| Journal: | Curr Cancer Drug Targets. 2008 Sep;8(6):454-65. | ||||||||||
| Title: | Importance of Wnt signaling in the tumor stroma microenvironment. | ||||||||||
| Author: | Macheda, Maria L|Stacker, Steven A | ||||||||||
| PMID: | 18781892 | ||||||||||
| 55. | |||||||||||
| Journal: | Mol Cancer Res. 2008 Sep;6(9):1421-30. | ||||||||||
| Title: | Sox7 Is an independent checkpoint for beta-catenin function in prostate and colon epithelial cells. | ||||||||||
| Author: | Guo, Lizheng|Zhong, Diansheng|Lau, Stephen|Liu, Xiuju|Dong, Xue-Yuan|Sun, Xiaodong|Yang, Vincent W|Vertino, Paula M|Moreno, Carlos S|Varma, Vijay|Dong, Jin-Tang|Zhou, Wei | ||||||||||
| PMID: | 18819930 | ||||||||||
| 56. | |||||||||||
| Journal: | Hybridoma (Larchmt). 2009 Jun;28(3):183-8. | ||||||||||
| Title: | A novel monoclonal antibody specific to DIXDC1 protein. | ||||||||||
| Author: | Liu, Tantan|Wang, Lei|Chen, Qi|Zheng, Li|Zhu, Hongguang | ||||||||||
| PMID: | 19519246 | ||||||||||
| 57. | |||||||||||
| Journal: | Cancer Sci. 2009 Oct;100(10):1801-8. | ||||||||||
| Title: | DIXDC1 targets p21 and cyclin D1 via PI3K pathway activation to promote colon cancer cell proliferation. | ||||||||||
| Author: | Wang, Lei|Cao, Xi-Xi|Chen, Qi|Zhu, Teng-Fang|Zhu, Hong-Guang|Zheng, Li | ||||||||||
| PMID: | 19572978 | ||||||||||
| 58. | |||||||||||
| Journal: | J Biol Chem. 2009 Dec 18;284(51):35308-13. | ||||||||||
| Title: | Phosphatidylinositol 3-kinase signaling does not activate the wnt cascade. | ||||||||||
| Author: | Ng, Ser Sue|Mahmoudi, Tokameh|Danenberg, Esther|Bejaoui, Ines|de Lau, Wim|Korswagen, Hendrik C|Schutte, Mieke|Clevers, Hans | ||||||||||
| PMID: | 19850932 | ||||||||||
| 59. | |||||||||||
| Journal: | PLoS One. 2009 Nov 24;4(11):e7982. | ||||||||||
| Title: | Mutations in the human naked cuticle homolog NKD1 found in colorectal cancer alter Wnt/Dvl/beta-catenin signaling. | ||||||||||
| Author: | Guo, Jianhui|Cagatay, Tolga|Zhou, Guangjin|Chan, Chih-Chiang|Blythe, Shelby|Suyama, Kaye|Zheng, Li|Pan, Kaifeng|Qian, Chiping|Hamelin, Richard|Thibodeau, Stephen N|Klein, Peter S|Wharton, Keith A|Liu, Wanguo | ||||||||||
| PMID: | 19956716 | ||||||||||
| 60. | |||||||||||
| Journal: | Oncogene. 2010 Mar 18;29(11):1663-71. | ||||||||||
| Title: | Contribution of the 15 amino acid repeats of truncated APC to beta-catenin degradation and selection of APC mutations in colorectal tumours from FAP patients. | ||||||||||
| Author: | Kohler, E M|Brauburger, K|Behrens, J|Schneikert, J | ||||||||||
| PMID: | 19966865 | ||||||||||
| 61. | |||||||||||
| Journal: | Biol Chem. 2010 Feb-Mar;391(2-3):171-80. | ||||||||||
| Title: | MAP3K1 functionally interacts with Axin1 in the canonical Wnt signalling pathway. | ||||||||||
| Author: | Sue Ng, Ser|Mahmoudi, Tokameh|Li, Vivian S W|Hatzis, Pantelis|Boersema, Paul J|Mohammed, Shabaz|Heck, Albert J|Clevers, Hans | ||||||||||
| PMID: | 20128690 | ||||||||||
| 62. | |||||||||||
| Journal: | Mol Cancer. 2010 Aug 6;9:212. | ||||||||||
| Title: | The Wnt/beta-catenin pathway regulates growth and maintenance of colonospheres. | ||||||||||
| Author: | Kanwar, Shailender S|Yu, Yingjie|Nautiyal, Jyoti|Patel, Bhaumik B|Majumdar, Adhip P N | ||||||||||
| PMID: | 20691072 | ||||||||||
| 63. | |||||||||||
| Journal: | Nat Chem Biol. 2010 Nov;6(11):829-36. | ||||||||||
| Title: | Small-molecule inhibition of Wnt signaling through activation of casein kinase 1alpha. | ||||||||||
| Author: | Thorne, Curtis A|Hanson, Alison J|Schneider, Judsen|Tahinci, Emilios|Orton, Darren|Cselenyi, Christopher S|Jernigan, Kristin K|Meyers, Kelly C|Hang, Brian I|Waterson, Alex G|Kim, Kwangho|Melancon, Bruce|Ghidu, Victor P|Sulikowski, Gary A|LaFleur, Bonnie|S | ||||||||||
| PMID: | 20890287 | ||||||||||
| 64. | |||||||||||
| Journal: | PLoS One. 2010 Nov 30;5(11):e14127. | ||||||||||
| Title: | Independent interactions of phosphorylated beta-catenin with E-cadherin at cell-cell contacts and APC at cell protrusions. | ||||||||||
| Author: | Faux, Maree C|Coates, Janine L|Kershaw, Nadia J|Layton, Meredith J|Burgess, Antony W | ||||||||||
| PMID: | 21152425 | ||||||||||
| 65. | |||||||||||
| Journal: | Cancer Genet Cytogenet. 2010 Dec;203(2):316-23. | ||||||||||
| Title: | Screening for common copy-number variants in cancer genes. | ||||||||||
| Author: | Tyson, Jess|Majerus, Tamsin M O|Walker, Susan|Armour, John A L | ||||||||||
| PMID: | 21156252 | ||||||||||
| 66. | |||||||||||
| Journal: | Med Oncol. 2011 Dec;28 Suppl 1:S259-67. | ||||||||||
| Title: | Diversity of axin in signaling pathways and its relation to colorectal cancer. | ||||||||||
| Author: | Parveen, Nighat|Hussain, Mahboob Ul|Pandith, Arshad A|Mudassar, Syed | ||||||||||
| PMID: | 21053101 | ||||||||||
| 67. | |||||||||||
| Journal: | Mol Cell Biochem. 2011 Sep;355(1-2):149-55. | ||||||||||
| Title: | Novelty of Axin 2 and lack of Axin 1 gene mutation in colorectal cancer: a study in Kashmiri population. | ||||||||||
| Author: | Khan, Nighat P|Pandith, Arshad A|Hussain, Mahboob Ul|Yousuf, Adfar|Khan, Mosin S|Wani, Khursheed A|Mudassar, Syed | ||||||||||
| PMID: | 21541676 | ||||||||||
| 68. | |||||||||||
| Journal: | Gastroenterology. 2012 Feb;142(2):219-32. | ||||||||||
| Title: | Dysregulation of Wnt/beta-catenin signaling in gastrointestinal cancers. | ||||||||||
| Author: | White, Bryan D|Chien, Andy J|Dawson, David W | ||||||||||
| PMID: | 22155636 | ||||||||||
| 69. | |||||||||||
| Journal: | Mol Biol Rep. 2012 May;39(5):6171-8. | ||||||||||
| Title: | Epigenetic and genetic analysis of WNT signaling pathway in sporadic colorectal cancer patients from Iran. | ||||||||||
| Author: | Naghibalhossaini, Fakhraddin|Zamani, Mozhdeh|Mokarram, Pooneh|Khalili, Islam|Rasti, Mozhgan|Mostafavi-Pour, Zohreh | ||||||||||
| PMID: | 22207181 | ||||||||||
| 70. | |||||||||||
| Journal: | PLoS One. 2012;7(2):e31882. | ||||||||||
| Title: | Wnt signalling pathway parameters for mammalian cells. | ||||||||||
| Author: | Tan, Chin Wee|Gardiner, Bruce S|Hirokawa, Yumiko|Layton, Meredith J|Smith, David W|Burgess, Antony W | ||||||||||
| PMID: | 22363759 | ||||||||||
| 71. | |||||||||||
| Journal: | Cell. 2012 Jun 8;149(6):1245-56. | ||||||||||
| Title: | Wnt signaling through inhibition of beta-catenin degradation in an intact Axin1 complex. | ||||||||||
| Author: | Li, Vivian S W|Ng, Ser Sue|Boersema, Paul J|Low, Teck Y|Karthaus, Wouter R|Gerlach, Jan P|Mohammed, Shabaz|Heck, Albert J R|Maurice, Madelon M|Mahmoudi, Tokameh|Clevers, Hans | ||||||||||
| PMID: | 22682247 | ||||||||||
| 72. | |||||||||||
| Journal: | PLoS One. 2012;7(11):e48670. | ||||||||||
| Title: | Inhibition of tankyrases induces Axin stabilization and blocks Wnt signalling in breast cancer cells. | ||||||||||
| Author: | Bao, Renyue|Christova, Tania|Song, Siyuan|Angers, Stephane|Yan, Xiaojun|Attisano, Liliana | ||||||||||
| PMID: | 23144924 | ||||||||||
| 73. | |||||||||||
| Journal: | Turk Patoloji Derg. 2013;29(2):87-93. | ||||||||||
| Title: | Relationship between beta-catenin expression and prognostic parameters of colorectal carcinomas. | ||||||||||
| Author: | Peker, Kemal|Basoglu, Mahmut|Gursan, Nesrin | ||||||||||
| PMID: | 23661344 | ||||||||||
| 74. | |||||||||||
| Journal: | Dig Dis Sci. 2013 Sep;58(9):2507-17. | ||||||||||
| Title: | Inhibitory effect of a standardized pomegranate fruit extract on Wnt signalling in 1, 2-dimethylhydrazine induced rat colon carcinogenesis. | ||||||||||
| Author: | Sadik, Nermin Abdel Hamid|Shaker, Olfat Gamil | ||||||||||
| PMID: | 23722564 | ||||||||||
| 75. | |||||||||||
| Journal: | PLoS Comput Biol. 2013;9(9):e1003217. | ||||||||||
| Title: | Modeling the effect of APC truncation on destruction complex function in colorectal cancer cells. | ||||||||||
| Author: | Barua, Dipak|Hlavacek, William S | ||||||||||
| PMID: | 24086117 | ||||||||||
| 76. | |||||||||||
| Journal: | J Med Chem. 2013 Dec 27;56(24):10003-15. | ||||||||||
| Title: | Development of novel dual binders as potent, selective, and orally bioavailable tankyrase inhibitors. | ||||||||||
| Author: | Hua, Zihao|Bregman, Howard|Buchanan, John L|Chakka, Nagasree|Guzman-Perez, Angel|Gunaydin, Hakan|Huang, Xin|Gu, Yan|Berry, Virginia|Liu, Jingzhou|Teffera, Yohannes|Huang, Liyue|Egge, Bryan|Emkey, Renee|Mullady, Erin L|Schneider, Steve|Andrews, Paul S|Acqu | ||||||||||
| PMID: | 24294969 | ||||||||||
| 77. | |||||||||||
| Journal: | ACS Med Chem Lett. 2013 Oct 21;4(12):1218-23. | ||||||||||
| Title: | Structure-based design of 2-aminopyridine oxazolidinones as potent and selective tankyrase inhibitors. | ||||||||||
| Author: | Huang, Hongbing|Guzman-Perez, Angel|Acquaviva, Lisa|Berry, Virginia|Bregman, Howard|Dovey, Jennifer|Gunaydin, Hakan|Huang, Xin|Huang, Liyue|Saffran, Doug|Serafino, Randy|Schneider, Steve|Wilson, Cindy|DiMauro, Erin F | ||||||||||
| PMID: | 24900633 | ||||||||||
| 78. | |||||||||||
| Journal: | Cancer Res. 2014 Mar 1;74(5):1495-505. | ||||||||||
| Title: | LEF1 and B9L shield beta-catenin from inactivation by Axin, desensitizing colorectal cancer cells to tankyrase inhibitors. | ||||||||||
| Author: | de la Roche, Marc|Ibrahim, Ashraf E K|Mieszczanek, Juliusz|Bienz, Mariann | ||||||||||
| PMID: | 24419084 | ||||||||||
| 79. | |||||||||||
| Journal: | PLoS One. 2014 Apr 10;9(4):e94413. | ||||||||||
| Title: | different Roles for the axin interactions with the SAMP versus the second twenty amino acid repeat of adenomatous polyposis coli. | ||||||||||
| Author: | Schneikert, Jean|Ruppert, Jan Gustav|Behrens, Jurgen|Wenzel, Eva Maria | ||||||||||
| PMID: | 24722208 | ||||||||||
| 80. | |||||||||||
| Journal: | J Cell Sci. 2014 Jul 15;127(Pt 14):3116-30. | ||||||||||
| Title: | The metastasis suppressor NDRG1 modulates the phosphorylation and nuclear translocation of beta-catenin through mechanisms involving FRAT1 and PAK4. | ||||||||||
| Author: | Jin, Runsen|Liu, Wensheng|Menezes, Sharleen|Yue, Fei|Zheng, Minhua|Kovacevic, Zaklina|Richardson, Des R | ||||||||||
| PMID: | 24829151 | ||||||||||
| 81. | |||||||||||
| Journal: | Oncol Lett. 2014 Jun;7(6):2185-2191. | ||||||||||
| Title: | FBXL20 acts as an invasion inducer and mediates E-cadherin in colorectal adenocarcinoma. | ||||||||||
| Author: | Zhu, Jianjun|Deng, Shishan|Duan, Jie|Xie, Xingguo|Xu, Shiquan|Ran, Maocheng|Dai, Xiaosi|Pu, Yu|Zhang, Xiaoming | ||||||||||
| PMID: | 24932313 | ||||||||||
| 82. | |||||||||||
| Journal: | PLoS One. 2014 Sep 15;9(9):e106881. | ||||||||||
| Title: | Open tubular lab-on-column/mass spectrometry for targeted proteomics of nanogram sample amounts. | ||||||||||
| Author: | Hustoft, Hanne Kolsrud|Vehus, Tore|Brandtzaeg, Ole Kristian|Krauss, Stefan|Greibrokk, Tyge|Wilson, Steven Ray|Lundanes, Elsa | ||||||||||
| PMID: | 25222838 | ||||||||||
| 83. | |||||||||||
| Journal: | Cancer Lett. 2014 Dec 1;355(1):1-8. | ||||||||||
| Title: | |||||||||||