Primary Site >> Colorectal Cancer
Gene >> AURKB
| 1. | |||||||||||
| Journal: | EMBO J. 1998 Jun 1;17(11):3052-65. | ||||||||||
| Title: | A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers. | ||||||||||
| Author: | Bischoff, J R|Anderson, L|Zhu, Y|Mossie, K|Ng, L|Souza, B|Schryver, B|Flanagan, P|Clairvoyant, F|Ginther, C|Chan, C S|Novotny, M|Slamon, D J|Plowman, G D | ||||||||||
| PMID: | 9606188 | ||||||||||
| 2. | |||||||||||
| Journal: | Jpn J Cancer Res. 2000 Oct;91(10):1007-14. | ||||||||||
| Title: | Centrosomal kinases, HsAIRK1 and HsAIRK3, are overexpressed in primary colorectal cancers. | ||||||||||
| Author: | Takahashi, T|Futamura, M|Yoshimi, N|Sano, J|Katada, M|Takagi, Y|Kimura, M|Yoshioka, T|Okano, Y|Saji, S | ||||||||||
| PMID: | 11050471 | ||||||||||
| 3. | |||||||||||
| Journal: | Chromosoma. 2001 May;110(2):65-74. | ||||||||||
| Title: | Human INCENP colocalizes with the Aurora-B/AIRK2 kinase on chromosomes and is overexpressed in tumour cells. | ||||||||||
| Author: | Adams, R R|Eckley, D M|Vagnarelli, P|Wheatley, S P|Gerloff, D L|Mackay, A M|Svingen, P A|Kaufmann, S H|Earnshaw, W C | ||||||||||
| PMID: | 11453556 | ||||||||||
| 4. | |||||||||||
| Journal: | Cancer Res. 2002 Sep 15;62(18):5168-77. | ||||||||||
| Title: | Increased mitotic phosphorylation of histone H3 attributable to AIM-1/Aurora-B overexpression contributes to chromosome number instability. | ||||||||||
| Author: | Ota, Takahide|Suto, Shiho|Katayama, Hiroshi|Han, Zhen-Bo|Suzuki, Fumio|Maeda, Masayo|Tanino, Mikio|Terada, Yasuhiko|Tatsuka, Masaaki | ||||||||||
| PMID: | 12234980 | ||||||||||
| 5. | |||||||||||
| Journal: | Mol Cancer Ther. 2003 Mar;2(3):283-94. | ||||||||||
| Title: | Targeting aurora2 kinase in oncogenesis: a structural bioinformatics approach to target validation and rational drug design. | ||||||||||
| Author: | Vankayalapati, Hariprasad|Bearss, David J|Saldanha, Jose W|Munoz, Ruben M|Rojanala, Sangeeta|Von Hoff, Daniel D|Mahadevan, Daruka | ||||||||||
| PMID: | 12657723 | ||||||||||
| 6. | |||||||||||
| Journal: | Clin Cancer Res. 2007 Jun 15;13(12):3682-8. | ||||||||||
| Title: | AZD1152, a selective inhibitor of Aurora B kinase, inhibits human tumor xenograft growth by inducing apoptosis. | ||||||||||
| Author: | Wilkinson, Robert W|Odedra, Rajesh|Heaton, Simon P|Wedge, Stephen R|Keen, Nicholas J|Crafter, Claire|Foster, John R|Brady, Madeleine C|Bigley, Alison|Brown, Elaine|Byth, Kate F|Barrass, Nigel C|Mundt, Kirsten E|Foote, Kevin M|Heron, Nicola M|Jung, Frederi | ||||||||||
| PMID: | 17575233 | ||||||||||
| 7. | |||||||||||
| Journal: | Cell Cycle. 2007 Dec 15;6(24):3114-31. | ||||||||||
| Title: | The cyclin-dependent kinase inhibitor seliciclib (R-roscovitine; CYC202) decreases the expression of mitotic control genes and prevents entry into mitosis. | ||||||||||
| Author: | Whittaker, Steven R|Te Poele, Robert H|Chan, Florence|Linardopoulos, Spiros|Walton, Michael I|Garrett, Michelle D|Workman, Paul | ||||||||||
| PMID: | 18075315 | ||||||||||
| 8. | |||||||||||
| Journal: | Cell Prolif. 2008 Aug;41(4):645-59. | ||||||||||
| Title: | Reduced level of the spindle checkpoint protein BUB1B is associated with aneuploidy in colorectal cancers. | ||||||||||
| Author: | Burum-Auensen, E|DeAngelis, P M|Schjolberg, A R|Roislien, J|Mjaland, O|Clausen, O P F | ||||||||||
| PMID: | 18699967 | ||||||||||
| 9. | |||||||||||
| Journal: | Int J Cancer. 2009 Sep 1;125(5):996-1003. | ||||||||||
| Title: | Rimonabant inhibits human colon cancer cell growth and reduces the formation of precancerous lesions in the mouse colon. | ||||||||||
| Author: | Santoro, Antonietta|Pisanti, Simona|Grimaldi, Claudia|Izzo, Angelo A|Borrelli, Francesca|Proto, Maria C|Malfitano, Anna M|Gazzerro, Patrizia|Laezza, Chiara|Bifulco, Maurizio | ||||||||||
| PMID: | 19479993 | ||||||||||
| 10. | |||||||||||
| Journal: | Mol Cancer Ther. 2009 Jul;8(7):2046-56. | ||||||||||
| Title: | Determinants for the efficiency of anticancer drugs targeting either Aurora-A or Aurora-B kinases in human colon carcinoma cells. | ||||||||||
| Author: | Kaestner, Phillip|Stolz, Ailine|Bastians, Holger | ||||||||||
| PMID: | 19584233 | ||||||||||
| 11. | |||||||||||
| Journal: | Anticancer Res. 2009 Nov;29(11):4381-7. | ||||||||||
| Title: | Aneuploidy is associated with TP53 expression but not with BRCA1 or TERT expression in sporadic colorectal cancer. | ||||||||||
| Author: | Schjolberg, Aasa R|Clausen, Ole Petter F|Burum-Auensen, Espen|De Angelis, Paula M | ||||||||||
| PMID: | 20032382 | ||||||||||
| 12. | |||||||||||
| Journal: | Cancer Chemother Pharmacol. 2010 Mar;65(4):707-17. | ||||||||||
| Title: | SNS-314, a pan-Aurora kinase inhibitor, shows potent anti-tumor activity and dosing flexibility in vivo. | ||||||||||
| Author: | Arbitrario, Jennifer P|Belmont, Brian J|Evanchik, Marc J|Flanagan, W Michael|Fucini, Raymond V|Hansen, Stig K|Harris, Shannon O|Hashash, Ahmad|Hoch, Ute|Hogan, Jennifer N|Howlett, Anthony R|Jacobs, Jeffrey W|Lam, Joni W|Ritchie, Sean C|Romanowski, Michael | ||||||||||
| PMID: | 19649632 | ||||||||||
| 13. | |||||||||||
| Journal: | J Med Chem. 2010 May 27;53(10):3973-4001. | ||||||||||
| Title: | Discovery of GSK1070916, a potent and selective inhibitor of Aurora B/C kinase. | ||||||||||
| Author: | Adams, Nicholas D|Adams, Jerry L|Burgess, Joelle L|Chaudhari, Amita M|Copeland, Robert A|Donatelli, Carla A|Drewry, David H|Fisher, Kelly E|Hamajima, Toshihiro|Hardwicke, Mary Ann|Huffman, William F|Koretke-Brown, Kristin K|Lai, Zhihong V|McDonald, Octerl | ||||||||||
| PMID: | 20420387 | ||||||||||
| 14. | |||||||||||
| Journal: | Cell Signal. 2010 Aug;22(8):1214-21. | ||||||||||
| Title: | RasV12 induces Survivin/AuroraB pathway conferring tumor cell apoptosis resistance. | ||||||||||
| Author: | Hadj-Slimane, Reda|Pamonsinlapatham, Perayot|Herbeuval, Jean-Philippe|Garbay, Christiane|Lepelletier, Yves|Raynaud, Francoise | ||||||||||
| PMID: | 20362665 | ||||||||||
| 15. | |||||||||||
| Journal: | Mol Cancer. 2010 Feb 22;9:42. | ||||||||||
| Title: | Antineoplastic effects of an Aurora B kinase inhibitor in breast cancer. | ||||||||||
| Author: | Gully, Christopher P|Zhang, Fanmao|Chen, Jian|Yeung, James A|Velazquez-Torres, Guermarie|Wang, Edward|Yeung, Sai-Ching Jim|Lee, Mong-Hong | ||||||||||
| PMID: | 20175926 | ||||||||||
| 16. | |||||||||||
| Journal: | Pharmacogenomics J. 2011 Apr;11(2):93-9. | ||||||||||
| Title: | Pharmacogenetic profiling of Aurora kinase B is associated with overall survival in metastatic colorectal cancer. | ||||||||||
| Author: | Pohl, A|Azuma, M|Zhang, W|Yang, D|Ning, Y|Winder, T|Danenberg, K|Lenz, H-J | ||||||||||
| PMID: | 20368716 | ||||||||||
| 17. | |||||||||||
| Journal: | J Pathol. 2011 Oct;225(2):243-54. | ||||||||||
| Title: | Aberrantly expressed AURKC enhances the transformation and tumourigenicity of epithelial cells. | ||||||||||
| Author: | Tsou, Jen-Hui|Chang, Kung-Chao|Chang-Liao, Pey-Yi|Yang, Shu-Ting|Lee, Chung-Ta|Chen, Ya-Ping|Lee, Yi-Chao|Lin, Bo-Wen|Lee, Jenq-Chang|Shen, Meng-Ru|Chuang, Chin-Kai|Chang, Wen-Chang|Wang, Ju-Ming|Hung, Liang-Yi | ||||||||||
| PMID: | 21710690 | ||||||||||
| 18. | |||||||||||
| Journal: | Oncol Lett. 2012 May;3(5):1109-1114. | ||||||||||
| Title: | Nuclear Aurora B and cytoplasmic Survivin expression is involved in lymph node metastasis of colorectal cancer. | ||||||||||
| Author: | Tuncel, Handan|Shimamoto, Fumio|Kaneko Guangying Qi, Hiroshi|Aoki, Eriko|Jikihara, Hiroshi|Nakai, Shiro|Takata, Takashi|Tatsuka, Masaaki | ||||||||||
| PMID: | 22783401 | ||||||||||
| 19. | |||||||||||
| Journal: | Cell Cycle. 2012 Jun 1;11(11):2149-58. | ||||||||||
| Title: | Preferential killing of p53-deficient cancer cells by reversine. | ||||||||||
| Author: | Jemaa, Mohamed|Galluzzi, Lorenzo|Kepp, Oliver|Boileve, Alice|Lissa, Delphine|Senovilla, Laura|Harper, Francis|Pierron, Gerard|Berardinelli, Francesco|Antoccia, Antonio|Castedo, Maria|Vitale, Ilio|Kroemer, Guido | ||||||||||
| PMID: | 22592527 | ||||||||||
| 20. | |||||||||||
| Journal: | J Neurooncol. 2012 Jul;108(3):349-60. | ||||||||||
| Title: | Aurora kinase B/C inhibition impairs malignant glioma growth in vivo. | ||||||||||
| Author: | Diaz, Roberto Jose|Golbourn, Brian|Shekarforoush, Maryam|Smith, Christian A|Rutka, James T | ||||||||||
| PMID: | 22382783 | ||||||||||
| 21. | |||||||||||
| Journal: | Mol Cancer Ther. 2012 Mar;11(3):710-9. | ||||||||||
| Title: | An integrated genomic approach to identify predictive biomarkers of response to the aurora kinase inhibitor PF-03814735. | ||||||||||
| Author: | Hook, Kenneth E|Garza, Scott J|Lira, Maruja E|Ching, Keith A|Lee, Nathan V|Cao, Joan|Yuan, Jing|Ye, Jingjing|Ozeck, Mark|Shi, Stephanie T|Zheng, Xianxian|Rejto, Paul A|Kan, Julie L C|Christensen, James G|Pavlicek, Adam | ||||||||||
| PMID: | 22222631 | ||||||||||
| 22. | |||||||||||
| Journal: | DNA Cell Biol. 2012 May;31(5):660-71. | ||||||||||
| Title: | Frequent increased gene copy number and high protein expression of tRNA (cytosine-5-)-methyltransferase (NSUN2) in human cancers. | ||||||||||
| Author: | Okamoto, Mayumi|Hirata, Sumi|Sato, Sunao|Koga, Satomi|Fujii, Mikiko|Qi, Guangying|Ogawa, Ikuko|Takata, Takashi|Shimamoto, Fumio|Tatsuka, Masaaki | ||||||||||
| PMID: | 22136356 | ||||||||||
| 23. | |||||||||||
| Journal: | Biochem Pharmacol. 2012 May 1;83(9):1217-28. | ||||||||||
| Title: | Acute sensitization of colon cancer cells to inflammatory cytokines by prophase arrest. | ||||||||||
| Author: | Kuratnik, Anton|Senapati, Virginia E|Verma, Rajeev|Mellone, Barbara G|Vella, Anthony T|Giardina, Charles | ||||||||||
| PMID: | 22306067 | ||||||||||
| 24. | |||||||||||
| Journal: | Cancer Lett. 2013 Jun 10;333(2):244-52. | ||||||||||
| Title: | Myristoylated Alanine-Rich protein Kinase C Substrate (MARCKS) expression modulates the metastatic phenotype in human and murine colon carcinoma in vitro and in vivo. | ||||||||||
| Author: | Rombouts, Krista|Carloni, Vinicio|Mello, Tommaso|Omenetti, Sara|Galastri, Sara|Madiai, Stefania|Galli, Andrea|Pinzani, Massimo | ||||||||||
| PMID: | 23376641 | ||||||||||
| 25. | |||||||||||
| Journal: | Br J Cancer. 2013 May 28;108(10):2013-20. | ||||||||||
| Title: | 212Pb-radioimmunotherapy potentiates paclitaxel-induced cell killing efficacy by perturbing the mitotic spindle checkpoint. | ||||||||||
| Author: | Yong, K J|Milenic, D E|Baidoo, K E|Brechbiel, M W | ||||||||||
| PMID: | 23632482 | ||||||||||
| 26. | |||||||||||
| Journal: | J Med Chem. 2013 Nov 27;56(22):9122-35. | ||||||||||
| Title: | Aurora isoform selectivity: design and synthesis of imidazo[4,5-b]pyridine derivatives as highly selective inhibitors of Aurora-A kinase in cells. | ||||||||||
| Author: | Bavetsias, Vassilios|Faisal, Amir|Crumpler, Simon|Brown, Nathan|Kosmopoulou, Magda|Joshi, Amar|Atrash, Butrus|Perez-Fuertes, Yolanda|Schmitt, Jessica A|Boxall, Katherine J|Burke, Rosemary|Sun, Chongbo|Avery, Sian|Bush, Katherine|Henley, Alan|Raynaud, Flor | ||||||||||
| PMID: | 24195668 | ||||||||||
| 27. | |||||||||||
| Journal: | J Exp Clin Cancer Res. 2014 Jan 29;33:13. | ||||||||||
| Title: | Inhibition of Aurora B by CCT137690 sensitizes colorectal cells to radiotherapy. | ||||||||||
| Author: | Wu, Xiaoyu|Liu, Wentao|Cao, Qinhong|Chen, Che|Chen, Zhiwei|Xu, Zhe|Li, Weisu|Liu, Fukun|Yao, Xuequan | ||||||||||
| PMID: | 24476310 | ||||||||||
| 28. | |||||||||||
| Journal: | Cell Cycle. 2015;14(23):3755-67. | ||||||||||
| Title: | Functional analysis of phosphorylation of the mitotic centromere-associated kinesin by Aurora B kinase in human tumor cells. | ||||||||||
| Author: | Ritter, Andreas|Sanhaji, Mourad|Friemel, Alexandra|Roth, Susanne|Rolle, Udo|Louwen, Frank|Yuan, Juping | ||||||||||
| PMID: | 26148251 | ||||||||||
| 29. | |||||||||||
| Journal: | Oncol Rep. 2015 Oct;34(4):1905-14. | ||||||||||
| Title: | Never in mitosis gene A-related kinase 6 and aurora kinase A: New gene biomarkers in the conversion from ulcerative colitis to colorectal cancer. | ||||||||||
| Author: | Gerceker, Emre|Boyacioglu, Seda Orenay|Kasap, Elmas|Baykan, Ahmed|Yuceyar, Hakan|Yildirim, Hatice|Ayhan, Semin|Ellidokuz, Ender|Korkmaz, Mehmet | ||||||||||
| PMID: | 26259750 | ||||||||||
| 30. | |||||||||||
| Journal: | Mol Cancer Ther. 2015 Jul;14(7):1693-704. | ||||||||||
| Title: | Daurinol Enhances the Efficacy of Radiotherapy in Lung Cancer via Suppression of Aurora Kinase A/B Expression. | ||||||||||
| Author: | Woo, Jong Kyu|Kang, Ju-Hee|Shin, DongYun|Park, Seong-Hyeok|Kang, Kyungsu|Nho, Chu Won|Seong, Je Kyung|Lee, Sang-Jin|Oh, Seung Hyun | ||||||||||
| PMID: | 25882311 | ||||||||||
| 31. | |||||||||||
| Journal: | Virchows Arch. 2015 May;466(5):503-15. | ||||||||||
| Title: | Aurora B expression and histone variant H1.4S27 phosphorylation are no longer coordinated during metaphase in aneuploid colorectal carcinomas. | ||||||||||
| Author: | Sijare, Fahima|Geissler, Anna-Lena|Fichter, Christiane D|Hergeth, Sonja P|Bogatyreva, Lioudmila|Hauschke, Dieter|Schneider, Robert|Werner, Martin|Lassmann, Silke | ||||||||||
| PMID: | 25680570 | ||||||||||
| 32. | |||||||||||
| Journal: | Eur J Med Chem. 2015 Jan 7;89:310-9. | ||||||||||
| Title: | In vitro and in vivo characterization of a benzofuran derivative, a potential anticancer agent, as a novel Aurora B kinase inhibitor. | ||||||||||
| Author: | Xie, Fang|Zhu, Hengrui|Zhang, Haoxing|Lang, Qingyu|Tang, Lisha|Huang, Qiang|Yu, Long | ||||||||||
| PMID: | 25462247 | ||||||||||
| 33. | |||||||||||
| Journal: | Tumour Biol. 2016 Mar;37(3):3071-80. | ||||||||||
| Title: | The potential role of the NEK6, AURKA, AURKB, and PAK1 genes in adenomatous colorectal polyps and colorectal adenocarcinoma. | ||||||||||
| Author: | Kasap, Elmas|Gerceker, Emre|Boyacioglu, Seda Orenay|Yuceyar, Hakan|Yildirm, Hatice|Ayhan, Semin|Korkmaz, Mehmet | ||||||||||
| PMID: | 26423403 | ||||||||||
| 34. | |||||||||||
| Journal: | PLoS One. 2016 Apr 20;11(4):e0153818. | ||||||||||
| Title: | Efficient Activation of Apoptotic Signaling during Mitotic Arrest with AK301. | ||||||||||
| Author: | Chopra, Avijeet|Bond, Michael J|Bleiler, Marina|Yeagley, Michelle|Wright, Dennis|Giardina, Charles | ||||||||||
| PMID: | 27097159 | ||||||||||
| 35. | |||||||||||
| Journal: | J Biol Chem. 2017 Feb 3;292(5):1910-1924. | ||||||||||
| Title: | Functional Effects of AKT3 on Aurora Kinase Inhibitor-induced Aneuploidy. | ||||||||||
| Author: | Noguchi, Kohji|Hongama, Keita|Hariki, Shiori|Nonomiya, Yuma|Katayama, Kazuhiro|Sugimoto, Yoshikazu | ||||||||||
| PMID: | 28028179 | ||||||||||
| 36. | |||||||||||
| Journal: | Oncotarget. 2017 Mar 14;8(11):18106-18117. | ||||||||||
| Title: | 3'-hydroxy-4'-methoxy-beta-methyl-beta-nitrostyrene inhibits tumorigenesis in colorectal cancer cells through ROS-mediated DNA damage and mitochondrial dysfunction. | ||||||||||
| Author: | Tsai, Chun-Hao|Hung, Amos C|Chen, Yuan-Yin|Chiu, Ya-Wen|Hsieh, Pei-Wen|Lee, Yi-Chen|Su, Yu-Han|Chang, Po-Chih|Hu, Stephen Chu-Sung|Yuan, Shyng-Shiou F | ||||||||||
| PMID: | 28178649 | ||||||||||
| 37. | |||||||||||
| Journal: | Nat Commun. 2018 Mar 16;9(1):1106. | ||||||||||
| Title: | PLK1 has tumor-suppressive potential in APC-truncated colon cancer cells. | ||||||||||
| Author: | Raab, Monika|Sanhaji, Mourad|Matthess, Yves|Horlin, Albrecht|Lorenz, Ioana|Dotsch, Christina|Habbe, Nils|Waidmann, Oliver|Kurunci-Csacsko, Elisabeth|Firestein, Ron|Becker, Sven|Strebhardt, Klaus | ||||||||||
| PMID: | 29549256 | ||||||||||
| 38. | |||||||||||
| Journal: | Eur J Med Chem. 2018 May 10;151:533-545. | ||||||||||
| Title: | Design and synthesis of BPR1K653 derivatives targeting the back pocket of Aurora kinases for selective isoform inhibition. | ||||||||||
| Author: | Ke, Yi-Yu|Chang, Chun-Ping|Lin, Wen-Hsing|Tsai, Chia-Hua|Chiu, I-Chen|Wang, Wan-Ping|Wang, Pei-Chen|Chen, Pei-Yi|Lin, Wen-Hsin|Chang, Chun-Feng|Kuo, Po-Chu|Song, Jen-Shin|Shih, Chuan|Hsieh, Hsing-Pang|Chi, Ya-Hui | ||||||||||
| PMID: | 29656197 | ||||||||||
| 39. | |||||||||||
| Journal: | Oncotarget. 2016 Jul 18;9(28):19525-19542. | ||||||||||
| Title: | Aurora B prevents premature removal of spindle assembly checkpoint proteins from the kinetochore: A key role for Aurora B in mitosis. | ||||||||||
| Author: | Gurden, Mark D|Anderhub, Simon J|Faisal, Amir|Linardopoulos, Spiros | ||||||||||
| PMID: | 29731963 | ||||||||||
| 40. | |||||||||||
| Journal: | Oncotarget. 2018 May 8;9(35):23960-23974. | ||||||||||
| Title: | Identification of different mutational profiles in cancers arising in specific colon segments by next generation sequencing. | ||||||||||
| Author: | Oliveira, Duarte Mendes|Laudanna, Carmelo|Migliozzi, Simona|Zoppoli, Pietro|Santamaria, Gianluca|Grillone, Katia|Elia, Laura|Mignogna, Chiara|Biamonte, Flavia|Sacco, Rosario|Corcione, Francesco|Viglietto, Giuseppe|Malanga, Donatella|Rizzuto, Antonia | ||||||||||
| PMID: | 29844865 | ||||||||||