Primary Site >> Pancreatic Cancer
Gene >> AURKA
| 1. | |||||||||||
| Journal: | Curr Med Chem Anticancer Agents. 2003 Jan;3(1):25-34. | ||||||||||
| Title: | Structure-based design of novel anti-cancer agents targeting aurora kinases. | ||||||||||
| Author: | Mahadevan, Daruka|Bearss, David J|Vankayalapati, Hariprasad | ||||||||||
| PMID: | 12678912 | ||||||||||
| 2. | |||||||||||
| Journal: | Clin Cancer Res. 2003 Mar;9(3):991-7. | ||||||||||
| Title: | Overexpression of oncogenic STK15/BTAK/Aurora A kinase in human pancreatic cancer. | ||||||||||
| Author: | Li, Donghui|Zhu, Jijiang|Firozi, Pervez F|Abbruzzese, James L|Evans, Douglas B|Cleary, Karen|Friess, Helmut|Sen, Subrata | ||||||||||
| PMID: | 12631597 | ||||||||||
| 3. | |||||||||||
| Journal: | Mol Cancer Ther. 2004 Apr;3(4):451-7. | ||||||||||
| Title: | The mitotic serine threonine kinase, Aurora-2, is a potential target for drug development in human pancreatic cancer. | ||||||||||
| Author: | Rojanala, Sangeeta|Han, Haiyong|Munoz, Ruben M|Browne, Walden|Nagle, Raymond|Von Hoff, Daniel D|Bearss, David J | ||||||||||
| PMID: | 15078988 | ||||||||||
| 4. | |||||||||||
| Journal: | Cancer Res. 2005 Apr 1;65(7):2899-905. | ||||||||||
| Title: | RNA interference targeting aurora kinase a suppresses tumor growth and enhances the taxane chemosensitivity in human pancreatic cancer cells. | ||||||||||
| Author: | Hata, Tatsuo|Furukawa, Toru|Sunamura, Makoto|Egawa, Shinichi|Motoi, Fuyuhiko|Ohmura, Noriyuki|Marumoto, Tomotoshi|Saya, Hideyuki|Horii, Akira | ||||||||||
| PMID: | 15805292 | ||||||||||
| 5. | |||||||||||
| Journal: | Cancer Genet Cytogenet. 2005 May;159(1):10-7. | ||||||||||
| Title: | AURKA amplification, chromosome instability, and centrosome abnormality in human pancreatic carcinoma cells. | ||||||||||
| Author: | Zhu, Jijiang|Abbruzzese, James L|Izzo, Julie|Hittelman, Walter N|Li, Donghui | ||||||||||
| PMID: | 15860351 | ||||||||||
| 6. | |||||||||||
| Journal: | Int J Biochem Cell Biol. 2005 Aug;37(8):1572-7. | ||||||||||
| Title: | Aurora kinases. | ||||||||||
| Author: | Bolanos-Garcia, Victor M | ||||||||||
| PMID: | 15896667 | ||||||||||
| 7. | |||||||||||
| Journal: | Cancer Sci. 2006 Jan;97(1):1-7. | ||||||||||
| Title: | Molecular mechanisms of pancreatic carcinogenesis. | ||||||||||
| Author: | Furukawa, Toru|Sunamura, Makoto|Horii, Akira | ||||||||||
| PMID: | 16367914 | ||||||||||
| 8. | |||||||||||
| Journal: | Oncogene. 2006 Aug 10;25(35):4831-9. Epub 2006 Mar 13. | ||||||||||
| Title: | AURKA is one of the downstream targets of MAPK1/ERK2 in pancreatic cancer. | ||||||||||
| Author: | Furukawa, T|Kanai, N|Shiwaku, H O|Soga, N|Uehara, A|Horii, A | ||||||||||
| PMID: | 16532023 | ||||||||||
| 9. | |||||||||||
| Journal: | Clin Cancer Res. 2007 May 15;13(10):3100-4. | ||||||||||
| Title: | Aurora-A and p16 polymorphisms contribute to an earlier age at diagnosis of pancreatic cancer in Caucasians. | ||||||||||
| Author: | Chen, Jinyun|Li, Donghui|Wei, Chongjuan|Sen, Subrata|Killary, Ann M|Amos, Christopher I|Evans, Douglas B|Abbruzzese, James L|Frazier, Marsha L | ||||||||||
| PMID: | 17505013 | ||||||||||
| 10. | |||||||||||
| Journal: | Prostate. 2008 Feb 1;68(2):139-51. | ||||||||||
| Title: | Deletion of PSCA increases metastasis of TRAMP-induced prostate tumors without altering primary tumor formation. | ||||||||||
| Author: | Moore, Miranda L|Teitell, Michael A|Kim, Yoon|Watabe, Tetsuro|Reiter, Robert E|Witte, Owen N|Dubey, Purnima | ||||||||||
| PMID: | 18044730 | ||||||||||
| 11. | |||||||||||
| Journal: | World J Gastroenterol. 2008 Mar 7;14(9):1378-82. | ||||||||||
| Title: | MK615 inhibits pancreatic cancer cell growth by dual inhibition of Aurora A and B kinases. | ||||||||||
| Author: | Okada, Toshie|Sawada, Tokihiko|Osawa, Tatsushi|Adachi, Masakazu|Kubota, Keiichi | ||||||||||
| PMID: | 18322951 | ||||||||||
| 12. | |||||||||||
| Journal: | Pancreas. 2008 Oct;37(3):e39-44. | ||||||||||
| Title: | Pdx-1-driven overexpression of aurora a kinase induces mild ductal dysplasia of pancreatic ducts near islets in transgenic mice. | ||||||||||
| Author: | Warner, Steven L|Munoz, Ruben M|Bearss, David J|Grippo, Paul|Han, Haiyong|Von Hoff, Daniel D | ||||||||||
| PMID: | 18815537 | ||||||||||
| 13. | |||||||||||
| Journal: | Environ Mol Mutagen. 2009 Oct;50(8):672-96. | ||||||||||
| Title: | Nucleation capacity and presence of centrioles define a distinct category of centrosome abnormalities that induces multipolar mitoses in cancer cells. | ||||||||||
| Author: | Difilippantonio, Michael J|Ghadimi, B Michael|Howard, Tamara|Camps, Jordi|Nguyen, Quang Tri|Ferris, Douglas K|Sackett, Dan L|Ried, Thomas | ||||||||||
| PMID: | 19768832 | ||||||||||
| 14. | |||||||||||
| Journal: | Clin Cancer Res. 2010 Jun 15;16(12):3171-81. | ||||||||||
| Title: | Aurora kinase A promotes ovarian tumorigenesis through dysregulation of the cell cycle and suppression of BRCA2. | ||||||||||
| Author: | Yang, Gong|Chang, Bin|Yang, Fan|Guo, Xiaoqing|Cai, Kathy Qi|Xiao, Xue Sherry|Wang, Huamin|Sen, Subrata|Hung, Mien-Chie|Mills, Gordon B|Chang, Sandy|Multani, Asha S|Mercado-Uribe, Imelda|Liu, Jinsong | ||||||||||
| PMID: | 20423983 | ||||||||||
| 15. | |||||||||||
| Journal: | Cancer Chemother Pharmacol. 2010 Mar;65(4):707-17. | ||||||||||
| Title: | SNS-314, a pan-Aurora kinase inhibitor, shows potent anti-tumor activity and dosing flexibility in vivo. | ||||||||||
| Author: | Arbitrario, Jennifer P|Belmont, Brian J|Evanchik, Marc J|Flanagan, W Michael|Fucini, Raymond V|Hansen, Stig K|Harris, Shannon O|Hashash, Ahmad|Hoch, Ute|Hogan, Jennifer N|Howlett, Anthony R|Jacobs, Jeffrey W|Lam, Joni W|Ritchie, Sean C|Romanowski, Michael | ||||||||||
| PMID: | 19649632 | ||||||||||
| 16. | |||||||||||
| Journal: | Cell Signal. 2012 Aug;24(8):1677-89. | ||||||||||
| Title: | A novel role for TPX2 as a scaffold and co-activator protein of the Chromosomal Passenger Complex. | ||||||||||
| Author: | Iyer, Jyoti|Tsai, Ming-Ying | ||||||||||
| PMID: | 22560880 | ||||||||||
| 17. | |||||||||||
| Journal: | Clin Cancer Res. 2012 Oct 1;18(19):5234-46. | ||||||||||
| Title: | Nupr1-aurora kinase A pathway provides protection against metabolic stress-mediated autophagic-associated cell death. | ||||||||||
| Author: | Hamidi, Tewfik|Cano, Carla E|Grasso, Daniel|Garcia, Maria Noe|Sandi, Maria Jose|Calvo, Ezequiel L|Dagorn, Jean-Charles|Lomberk, Gwen|Urrutia, Raul|Goruppi, Sandro|Carracedo, Arkaitz|Velasco, Guillermo|Iovanna, Juan L | ||||||||||
| PMID: | 22899799 | ||||||||||
| 18. | |||||||||||
| Journal: | Br J Cancer. 2012 Nov 6;107(10):1692-701. | ||||||||||
| Title: | Paclitaxel and CYC3, an aurora kinase A inhibitor, synergise in pancreatic cancer cells but not bone marrow precursor cells. | ||||||||||
| Author: | Lin, Y|Richards, F M|Krippendorff, B-F|Bramhall, J L|Harrington, J A|Bapiro, T E|Robertson, A|Zheleva, D|Jodrell, D I | ||||||||||
| PMID: | 23037716 | ||||||||||
| 19. | |||||||||||
| Journal: | Cell Death Differ. 2013 Mar;20(3):503-14. | ||||||||||
| Title: | The histone deacetylase SIRT2 stabilizes Myc oncoproteins. | ||||||||||
| Author: | Liu, P Y|Xu, N|Malyukova, A|Scarlett, C J|Sun, Y T|Zhang, X D|Ling, D|Su, S-P|Nelson, C|Chang, D K|Koach, J|Tee, A E|Haber, M|Norris, M D|Toon, C|Rooman, I|Xue, C|Cheung, B B|Kumar, S|Marshall, G M|Biankin, A V|Liu, T | ||||||||||
| PMID: | 23175188 | ||||||||||
| 20. | |||||||||||
| Journal: | Cancer Lett. 2013 Aug 19;336(2):270-80. | ||||||||||
| Title: | Holy Basil leaf extract decreases tumorigenicity and metastasis of aggressive human pancreatic cancer cells in vitro and in vivo: potential role in therapy. | ||||||||||
| Author: | Shimizu, Tomohiro|Torres, Maria P|Chakraborty, Subhankar|Souchek, Joshua J|Rachagani, Satyanarayana|Kaur, Sukhwinder|Macha, Muzafar|Ganti, Apar K|Hauke, Ralph J|Batra, Surinder K | ||||||||||
| PMID: | 23523869 | ||||||||||
| 21. | |||||||||||
| Journal: | Mol Cancer. 2014 Apr 28;13:94. | ||||||||||
| Title: | The negative interplay between Aurora A/B and BRCA1/2 controls cancer cell growth and tumorigenesis via distinct regulation of cell cycle progression, cytokinesis, and tetraploidy. | ||||||||||
| Author: | Wang, Yan|Wang, Ziliang|Qi, Zihao|Yin, Sheng|Zhang, Na|Liu, Yang|Liu, Mingming|Meng, Jiao|Zang, Rongyu|Zhang, Zhen|Yang, Gong | ||||||||||
| PMID: | 24775809 | ||||||||||
| 22. | |||||||||||
| Journal: | Oncotarget. 2015 May 10;6(13):10840-52. | ||||||||||
| Title: | The long non-coding RNA HOTTIP enhances pancreatic cancer cell proliferation, survival and migration. | ||||||||||
| Author: | Cheng, Yating|Jutooru, Indira|Chadalapaka, Gayathri|Corton, J Christopher|Safe, Stephen | ||||||||||
| PMID: | 25912306 | ||||||||||
| 23. | |||||||||||
| Journal: | J Cell Sci. 2017 Mar 15;130(6):1078-1093. | ||||||||||
| Title: | The Aurora-A-Twist1 axis promotes highly aggressive phenotypes in pancreatic carcinoma. | ||||||||||
| Author: | Wang, Jing|Nikhil, Kumar|Viccaro, Keith|Chang, Lei|Jacobsen, Max|Sandusky, George|Shah, Kavita | ||||||||||
| PMID: | 28167680 | ||||||||||
| 24. | |||||||||||
| Journal: | BMC Biol. 2017 Feb 13;15(1):10. | ||||||||||
| Title: | Phosphorylation-dependent regulation of ALDH1A1 by Aurora kinase A: insights on their synergistic relationship in pancreatic cancer. | ||||||||||
| Author: | Wang, Jing|Nikhil, Kumar|Viccaro, Keith|Chang, Lei|White, Jacoba|Shah, Kavita | ||||||||||
| PMID: | 28193222 | ||||||||||
| 25. | |||||||||||
| Journal: | Nat Commun. 2017 Feb 21;8:14294. | ||||||||||
| Title: | An integrative approach unveils FOSL1 as an oncogene vulnerability in KRAS-driven lung and pancreatic cancer. | ||||||||||
| Author: | Vallejo, Adrian|Perurena, Naiara|Guruceaga, Elisabet|Mazur, Pawel K|Martinez-Canarias, Susana|Zandueta, Carolina|Valencia, Karmele|Arricibita, Andrea|Gwinn, Dana|Sayles, Leanne C|Chuang, Chen-Hua|Guembe, Laura|Bailey, Peter|Chang, David K|Biankin, Andrew| | ||||||||||
| PMID: | 28220783 | ||||||||||
| 26. | |||||||||||
| Journal: | Mol Cancer Res. 2017 Aug;15(8):984-997. | ||||||||||
| Title: | Combined AURKA and H3K9 Methyltransferase Targeting Inhibits Cell Growth By Inducing Mitotic Catastrophe. | ||||||||||
| Author: | Mathison, Angela|Salmonson, Ann|Missfeldt, Mckenna|Bintz, Jennifer|Williams, Monique|Kossak, Sarah|Nair, Asha|de Assuncao, Thiago M|Christensen, Trace|Buttar, Navtej|Iovanna, Juan|Huebert, Robert|Lomberk, Gwen | ||||||||||
| PMID: | 28442587 | ||||||||||
| 27. | |||||||||||
| Journal: | Gastroenterology. 2017 Nov;153(5):1429-1443.e5. | ||||||||||
| Title: | Inhibition of Aurora Kinase A Induces Necroptosis in Pancreatic Carcinoma. | ||||||||||
| Author: | Xie, Yangchun|Zhu, Shan|Zhong, Meizuo|Yang, Manhua|Sun, Xiaofan|Liu, Jinbao|Kroemer, Guido|Lotze, Michael|Zeh, Herbert J 3rd|Kang, Rui|Tang, Daolin | ||||||||||
| PMID: | 28764929 | ||||||||||
| 28. | |||||||||||
| Journal: | Signal Transduct Target Ther. 2018 Apr 20;3:11. | ||||||||||
| Title: | Yes-associated protein (YAP) in pancreatic cancer: at the epicenter of a targetable signaling network associated with patient survival. | ||||||||||
| Author: | Rozengurt, Enrique|Sinnett-Smith, James|Eibl, Guido | ||||||||||
| PMID: | 29682330 | ||||||||||