Primary Site >> Liver Cancer

Gene >> AURKA

Journal: Cancer Res. 2003 Feb 15;63(4):859-64.
Title: Identification of novel tumor markers in hepatitis C virus-associated hepatocellular carcinoma.
Author: Smith, Maria W|Yue, Zhaoxia N|Geiss, Gary K|Sadovnikova, Natalya Y|Carter, Victoria S|Boix, Loreto|Lazaro, Catherine A|Rosenberg, Gary B|Bumgarner, Roger E|Fausto, Nelson|Bruix, Jordi|Katze, Michael G
PMID: 12591738
Journal: Clin Cancer Res. 2004 Mar 15;10(6):2065-71.
Title: Overexpression and amplification of Aurora-A in hepatocellular carcinoma.
Author: Jeng, Yung-Ming|Peng, Shian-Yang|Lin, Chiao-Ying|Hsu, Hey-Chi
PMID: 15041727
Journal: PLoS One. 2007 Sep 26;2(9):e944.
Title: Constitutive phosphorylation of aurora-a on ser51 induces its stabilization and consequent overexpression in cancer.
Author: Kitajima, Shojiro|Kudo, Yasusei|Ogawa, Ikuko|Tatsuka, Masaaki|Kawai, Hidehiko|Pagano, Michele|Takata, Takashi
PMID: 17895985
Journal: Cancer Sci. 2008 Nov;99(11):2209-17.
Title: Hypoxia-inducible enhancer/alpha-fetoprotein promoter-driven RNA interference targeting STK15 suppresses proliferation and induces apoptosis in human hepatocellular carcinoma cells.
Author: Gao, Ping|Wang, Rui|Shen, Jian-Jun|Lin, Fang|Wang, Xi|Dong, Ke|Zhang, Hui-Zhong
PMID: 18803637
Journal: PLoS One. 2013 Jun 5;8(6):e65264.
Title: Small molecule R1498 as a well-tolerated and orally active kinase inhibitor for hepatocellular carcinoma and gastric cancer treatment via targeting angiogenesis and mitosis pathways.
Author: Zhang, Chao|Wu, Xihan|Zhang, Meifang|Zhu, Liangcheng|Zhao, Rong|Xu, Danqing|Lin, Zhaohu|Liang, Chungen|Chen, Taiping|Chen, Li|Ren, Yi|Zhang, Joe|Qin, Ning|Zhang, Xiongwen
PMID: 23755206
Journal: Br J Cancer. 2013 Oct 29;109(9):2445-52.
Title: Aurora kinase A (AURKA) expression in colorectal cancer liver metastasis is associated with poor prognosis.
Author: Goos, J A C M|Coupe, V M H|Diosdado, B|Delis-Van Diemen, P M|Karga, C|Belien, J A M|Carvalho, B|van den Tol, M P|Verheul, H M W|Geldof, A A|Meijer, G A|Hoekstra, O S|Fijneman, R J A
PMID: 24104968
Journal: Mol Carcinog. 2015 Nov;54(11):1467-79.
Title: Aurora kinase A mediates c-Myc's oncogenic effects in hepatocellular carcinoma.
Author: Lu, Longfeng|Han, Han|Tian, Yuan|Li, Wenjuan|Zhang, Jinxiang|Feng, Maohui|Li, Youjun
PMID: 25284017
Journal: PLoS One. 2015 Apr 7;10(4):e0121298.
Title: Evaluation of the medicinal herb Graptopetalum paraguayense as a treatment for liver cancer.
Author: Hsu, Wei-Hsiang|Chang, Chia-Chuan|Huang, Kai-Wen|Chen, Yi-Chen|Hsu, Shih-Lan|Wu, Li-Chen|Tsou, Ann-Ping|Lai, Jin-Mei|Huang, Chi-Ying F
PMID: 25849560
Journal: Hepatology. 2015 Nov;62(5):1466-79.
Title: NUMB phosphorylation destabilizes p53 and promotes self-renewal of tumor-initiating cells by a NANOG-dependent mechanism in liver cancer.
Author: Siddique, Hifzur R|Feldman, Douglas E|Chen, Chia-Lin|Punj, Vasu|Tokumitsu, Hiroshi|Machida, Keigo
PMID: 26174965
Journal: J Proteome Res. 2015 Nov 6;14(11):4594-602.
Title: Quantitative Proteomics Reveals That the Inhibition of Na(+)/K(+)-ATPase Activity Affects S-Phase Progression Leading to a Chromosome Segregation Disorder by Attenuating the Aurora A Function in Hepatocellular Carcinoma Cells.
Author: Xu, Zhongwei|Wang, Fengmei|Fan, Fengxu|Gu, Yanjun|Shan, Nana|Meng, Xiangyan|Cheng, Shixiang|Liu, Yingfu|Wang, Chengyan|Song, Yueying|Xu, Ruicheng
PMID: 26491887
Journal: Nucl Med Biol. 2016 Jan;43(1):63-72.
Title: Molecular imaging of aurora kinase A (AURKA) expression: Synthesis and preclinical evaluation of radiolabeled alisertib (MLN8237).
Author: Goos, Jeroen A C M|Verbeek, Joost|Geldof, Albert A|Hiemstra, Annemieke C|van de Wiel, Mark A|Adamzek, Kevin A|Delis-Van Diemen, Pien M|Stroud, Stephen G|Bradley, Daniel P|Meijer, Gerrit A|Hoekstra, Otto S|Fijneman, Remond J A|Windhorst, Albert D
PMID: 26432753
Journal: Nat Med. 2016 Jul;22(7):744-53.
Title: A MYC-aurora kinase A protein complex represents an actionable drug target in p53-altered liver cancer.
Author: Dauch, Daniel|Rudalska, Ramona|Cossa, Giacomo|Nault, Jean-Charles|Kang, Tae-Won|Wuestefeld, Torsten|Hohmeyer, Anja|Imbeaud, Sandrine|Yevsa, Tetyana|Hoenicke, Lisa|Pantsar, Tatu|Bozko, Przemyslaw|Malek, Nisar P|Longerich, Thomas|Laufer, Stefan|Poso, Antti|
PMID: 27213815
Journal: Biochem Biophys Res Commun. 2017 Apr 29;486(2):514-520.
Title: AURKA promotes cancer metastasis by regulating epithelial-mesenchymal transition and cancer stem cell properties in hepatocellular carcinoma.
Author: Chen, Chenlin|Song, Guangyuan|Xiang, Jue|Zhang, Hongcheng|Zhao, Shaoyun|Zhan, Yinchu
PMID: 28322787
Journal: Am J Transl Res. 2017 Aug 15;9(8):3558-3572. eCollection 2017.
Title: A proteomics-based investigation on the anticancer activity of alisertib, an Aurora kinase A inhibitor, in hepatocellular carcinoma Hep3B cells.
Author: Zhu, Qiaohua|Luo, Meihua|Zhou, Chengyu|Zhou, Zhiwei|He, Zhixu|Yu, Xinfa|Zhou, Shufeng
PMID: 28861148
Journal: Oncotarget. 2017 Jun 27;8(33):54904-54912.
Title: Association between the functional polymorphism Ile31Phe in the AURKA gene and susceptibility of hepatocellular carcinoma in chronic hepatitis B virus carriers.
Author: Bao, Zhiyu|Lu, Lei|Liu, Xinyi|Guo, Bingqian|Zhai, Yun|Li, Yuanfeng|Wang, Yahui|Xie, Bobo|Ren, Qian|Cao, Pengbo|Han, Yuqing|Jia, Weihua|Chen, Minshan|Liang, Xinqiang|Wang, Xuan|Zeng, Yi-Xin|He, Fuchu|Zhang, Hongxing|Cui, Ying|Zhou, Gangqiao
PMID: 28903390
Journal: Int J Med Sci. 2018 Jan 1;15(2):170-175.
Title: Variations in the AURKA Gene: Biomarkers for the Development and Progression of Hepatocellular Carcinoma.
Author: Wang, Bin|Hsu, Chin-Jung|Chou, Chia-Hsuan|Lee, Hsiang-Lin|Chiang, Whei-Ling|Su, Chen-Ming|Tsai, Hsiao-Chi|Yang, Shun-Fa|Tang, Chih-Hsin
PMID: 29333101
Journal: Theranostics. 2018 Feb 12;8(6):1740-1751.
Title: Genomic analysis of liver cancer unveils novel driver genes and distinct prognostic features.
Author: Li, Xiangchun|Xu, Weiqi|Kang, Wei|Wong, Sunny H|Wang, Mengyao|Zhou, Yong|Fang, Xiaodong|Zhang, Xiuqing|Yang, Huanming|Wong, Chi H|To, Ka F|Chan, Stephen L|Chan, Matthew T V|Sung, Joseph J Y|Wu, William K K|Yu, Jun
PMID: 29556353
Journal: Onco Targets Ther. 2018 Apr 4;11:1861-1869.
Title: Identification of molecular target genes and key pathways in hepatocellular carcinoma by bioinformatics analysis.
Author: Zhou, Lei|Du, Yanyan|Kong, Lingqun|Zhang, Xingyuan|Chen, Qiangpu
PMID: 29670361
Journal: Cancer Biomark. 2018;22(3):511-521.
Title: Screening and function analysis of hub genes and pathways in hepatocellular carcinoma via bioinformatics approaches.
Author: Zhang, Liang|Huang, Yi|Ling, Junjun|Zhuo, Wenlei|Yu, Zhen|Shao, Mengmeng|Luo, Yunbo|Zhu, Yi
PMID: 29843214
Journal: Hepatol Commun. 2018 May 21;2(7):861-871.
Title: MicroRNA-26-5p functions as a new inhibitor of hepatoblastoma by repressing lin-28 homolog B and aurora kinase a expression.
Author: Zhang, Yutong|Zhao, Yulan|Wu, Jianguo|Liangpunsakul, Suthat|Niu, Junqi|Wang, Li
PMID: 30027143
Journal: Thyroid. 2018 Sep 18.
Title: c-Myc is a major determinant for antitumor activity of Aurora A kinase inhibitor MLN8237 in thyroid cancer.
Author: Li, Yiqi|Li, Xinru|Pu, Jun|Yang, Qi|Guan, Haixia|Ji, Meiju|Shi, Bingyin|Chen, Mingwei|Hou, Peng
PMID: 30226440