Primary Site >> Liver Cancer
Gene >> AURKA
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Ref: Identification of novel tumor markers in hepatitis C virus-associated hepatocellular carcinoma. PMID: 12591738 |
Ref: Overexpression and amplification of Aurora-A in hepatocellular carcinoma. PMID: 15041727 |
Ref: Constitutive phosphorylation of aurora-a on ser51 induces its stabilization and consequent overexpression in cancer. PMID: 17895985 |
Ref: Hypoxia-inducible enhancer/alpha-fetoprotein promoter-driven RNA interference targeting STK15 suppresses proliferation and induces apoptosis in human hepatocellular carcinoma cells. PMID: 18803637 |
Ref: Small molecule R1498 as a well-tolerated and orally active kinase inhibitor for hepatocellular carcinoma and gastric cancer treatment via targeting angiogenesis and mitosis pathways. PMID: 23755206 Ref: Aurora kinase A (AURKA) expression in colorectal cancer liver metastasis is associated with poor prognosis. PMID: 24104968 |
Ref: Aurora kinase A mediates c-Myc's oncogenic effects in hepatocellular carcinoma. PMID: 25284017 Ref: Evaluation of the medicinal herb Graptopetalum paraguayense as a treatment for liver cancer. PMID: 25849560 Ref: NUMB phosphorylation destabilizes p53 and promotes self-renewal of tumor-initiating cells by a NANOG-dependent mechanism in liver cancer. PMID: 26174965 Ref: Quantitative Proteomics Reveals That the Inhibition of Na(+)/K(+)-ATPase Activity Affects S-Phase Progression Leading to a Chromosome Segregation Disorder by Attenuating the Aurora A Function in Hepatocellular Carcinoma Cells. PMID: 26491887 |
Ref: Molecular imaging of aurora kinase A (AURKA) expression: Synthesis and preclinical evaluation of radiolabeled alisertib (MLN8237). PMID: 26432753 Ref: A MYC-aurora kinase A protein complex represents an actionable drug target in p53-altered liver cancer. PMID: 27213815 |
Ref: AURKA promotes cancer metastasis by regulating epithelial-mesenchymal transition and cancer stem cell properties in hepatocellular carcinoma. PMID: 28322787 Ref: A proteomics-based investigation on the anticancer activity of alisertib, an Aurora kinase A inhibitor, in hepatocellular carcinoma Hep3B cells. PMID: 28861148 Ref: Association between the functional polymorphism Ile31Phe in the AURKA gene and susceptibility of hepatocellular carcinoma in chronic hepatitis B virus carriers. PMID: 28903390 |
Ref: Variations in the AURKA Gene: Biomarkers for the Development and Progression of Hepatocellular Carcinoma. PMID: 29333101 Ref: Genomic analysis of liver cancer unveils novel driver genes and distinct prognostic features. PMID: 29556353 Ref: Identification of molecular target genes and key pathways in hepatocellular carcinoma by bioinformatics analysis. PMID: 29670361 Ref: Screening and function analysis of hub genes and pathways in hepatocellular carcinoma via bioinformatics approaches. PMID: 29843214 Ref: MicroRNA-26-5p functions as a new inhibitor of hepatoblastoma by repressing lin-28 homolog B and aurora kinase a expression. PMID: 30027143 Ref: c-Myc is a major determinant for antitumor activity of Aurora A kinase inhibitor MLN8237 in thyroid cancer. PMID: 30226440 |