Primary Site >> Stomach Cancer

Gene >> AURKA

Journal: Cancer Res Treat. 2001 Aug;33(4):309-17.
Title: Genetic Alterations in Gastric Carcinomas and Adjacent Mucosa Detected by Comparative Genomic Hybridization (CGH).
Author: Kim, D W|Choi, S J|Lee, J Y|Kim, K J|Park, M I|Park, S J|Koo, S H|Koo, J Y
PMID: 26680801
Journal: Br J Cancer. 2001 Mar 23;84(6):824-31.
Title: Tumour-amplified kinase BTAK is amplified and overexpressed in gastric cancers with possible involvement in aneuploid formation.
Author: Sakakura, C|Hagiwara, A|Yasuoka, R|Fujita, Y|Nakanishi, M|Masuda, K|Shimomura, K|Nakamura, Y|Inazawa, J|Abe, T|Yamagishi, H
PMID: 11259099
Journal: Hepatogastroenterology. 2003 Nov-Dec;50(54):1857-63.
Title: Chromosome arm 20q gains and other genomic alterations in esophageal squamous cell carcinoma, as analyzed by comparative genomic hybridization and fluorescence in situ hybridization.
Author: Fujita, Yoshifumi|Sakakura, Chouhei|Shimomura, Katsumi|Nakanishi, Masayoshi|Yasuoka, Rie|Aragane, Hideki|Hagiwara, Akeo|Abe, Tatsuo|Inazawa, Johji|Yamagishi, Hisakazu
PMID: 14696419
Journal: Int J Oncol. 2003 Jun;22(6):1369-74.
Title: MGC9753 gene, located within PPP1R1B-STARD3-ERBB2-GRB7 amplicon on human chromosome 17q12, encodes the seven-transmembrane receptor with extracellular six-cystein domain.
Author: Katoh, Masuko|Katoh, Masaru
PMID: 12739007
Journal: Oncol Rep. 2004 Sep;12(3):593-9.
Title: Amplification/overexpression of Aurora-A in human gastric carcinoma: potential role in differentiated type gastric carcinogenesis.
Author: Kamada, Kiyoshi|Yamada, Yukishige|Hirao, Tomoko|Fujimoto, Heisuke|Takahama, Yasushi|Ueno, Masatoh|Takayama, Tomoyoshi|Naito, Akihiko|Hirao, Shuya|Nakajima, Yoshiyuki
PMID: 15289843
Journal: Cancer Lett. 2006 Oct 28;242(2):273-9. Epub 2006 Jan 18.
Title: Functional polymorphism 57Val>Ile of aurora kinase A associated with increased risk of gastric cancer progression.
Author: Ju, Hyoungseok|Cho, Hyunmi|Kim, Yong Sung|Kim, Woo Ho|Ihm, Chunhwa|Noh, Seung-Moo|Kim, Jin-Bok|Hahn, Dong-Soo|Choi, Bo-Yuol|Kang, Changwon
PMID: 16412566
Journal: Zhonghua Bing Li Xue Za Zhi. 2006 Feb;35(2):106-9.
Title: [Mitotic arrest of gastric cancer cells induced by silencing of STK15 gene].
Author: Lan, Bin|Chen, Xue-hua|Liu, Bing-ya|Qu, Ying|Zhang, Xiao-qing|Cai, Qu|Dai, Qi-bao|Zhang, Jian|Zhu, Zheng-gang
PMID: 16630486
Journal: Zhonghua Wei Chang Wai Ke Za Zhi. 2006 Sep;9(5):417-20.
Title: [Inhibition of serine/threonine kinase 15 gene expression induces apoptosis of gastric cancer cells].
Author: Lan, Bin|Liu, Bing-ya|Chen, Xue-hua|Qu, Ying|Zhang, Xiao-qing|Cai, Qu|Dai, Qi-bao|Zhang, Jian|Zhu, Zheng-Gang
PMID: 17043964
Journal: Zhonghua Zhong Liu Za Zhi. 2006 Aug;28(8):568-71.
Title: [Analysis of gene expression profiles in gastric cancer cell cycle].
Author: Lan, Bin|Liu, Bin-ya|Cheng, Xue-hua|Zhang, Ji|Wang, Kan-kan|Zhu, Zheng-gang
PMID: 17236548
Journal: J Cell Sci. 2007 Sep 1;120(Pt 17):2987-96.
Title: Aurora-A: the maker and breaker of spindle poles.
Author: Barr, Alexis R|Gergely, Fanni
PMID: 17715155
Journal: PLoS One. 2007 Sep 26;2(9):e944.
Title: Constitutive phosphorylation of aurora-a on ser51 induces its stabilization and consequent overexpression in cancer.
Author: Kitajima, Shojiro|Kudo, Yasusei|Ogawa, Ikuko|Tatsuka, Masaaki|Kawai, Hidehiko|Pagano, Michele|Takata, Takashi
PMID: 17895985
Journal: PLoS One. 2008 Mar 12;3(3):e1776.
Title: The anti-proliferative effects of the CHFR depend on the forkhead associated domain, but not E3 ligase activity mediated by ring finger domain.
Author: Fukuda, Tomokazu|Kondo, Yasuyuki|Nakagama, Hitoshi
PMID: 18335050
Journal: Oncogene. 2009 Feb 12;28(6):866-75.
Title: The aurora kinase A regulates GSK-3beta in gastric cancer cells.
Author: Dar, A A|Belkhiri, A|El-Rifai, W
PMID: 19060929
Journal: Eur J Cancer. 2009 Dec;45(18):3326-35.
Title: CyclinD1 and interleukin-1 receptor antagonist polymorphisms are associated with prognosis in neoadjuvant-treated gastric carcinoma.
Author: Stocker, Gertraud|Ott, Katja|Henningsen, Nils|Becker, Karen|Hapfelmeier, Alexander|Lordick, Florian|Hois, Stefan|Plaschke, Susanne|Hofler, Heinz|Keller, Gisela
PMID: 19822419
Journal: Mol Cancer Ther. 2010 Apr;9(4):883-94.
Title: PF-03814735, an orally bioavailable small molecule aurora kinase inhibitor for cancer therapy.
Author: Jani, Jitesh P|Arcari, Joel|Bernardo, Vincent|Bhattacharya, Samit K|Briere, David|Cohen, Bruce D|Coleman, Kevin|Christensen, James G|Emerson, Erling O|Jakowski, Amy|Hook, Kenneth|Los, Gerrit|Moyer, James D|Pruimboom-Brees, Ingrid|Pustilnik, Leslie|Rossi,
PMID: 20354118
Journal: Med Oncol. 2011 Dec;28(4):1017-22.
Title: Copy-number increase of AURKA in gastric cancers in a Chinese population: a correlation with tumor progression.
Author: Fang, Zhengyu|Xiong, Yi|Li, Jiana|Liu, Li|Li, Manhui|Zhang, Chao|Zhang, Wei|Wan, Jun
PMID: 20585902
Journal: Oncol Rep. 2011 Jul;26(1):23-32.
Title: Aurora-A as an independent molecular prognostic marker in gastric cancer.
Author: Wang, Jing|Yang, Sheng|Zhang, Haizeng|Song, Yan|Zhang, Xun|Qian, Haili|Han, Xiaohong|Shi, Yuankai
PMID: 21479365
Journal: Nutr Cancer. 2011;63(7):1095-103.
Title: Capsaicin induces apoptosis of cisplatin-resistant stomach cancer cells by causing degradation of cisplatin-inducible Aurora-A protein.
Author: Huh, Hui-Chung|Lee, Sun-Young|Lee, Seung-Keun|Park, Neung Hwa|Han, In-Seob
PMID: 21932983
Journal: Asian Pac J Cancer Prev. 2011;12(10):2717-20.
Title: Inhibition of proliferation, viability, migration and invasion of gastric cancer cells by Aurora-A deletion.
Author: Wang, Wei|Zhang, Ning|Wang, Jian|Bu, Xian-Min|Zhao, Cheng-Hai
PMID: 22320980
Journal: Ann Surg Oncol. 2012 Oct;19(11):3491-9.
Title: Integrating bioinformatics and clinicopathological research of gastrointestinal stromal tumors: identification of aurora kinase A as a poor risk marker.
Author: Yen, Chueh-Chuan|Yeh, Chun-Nan|Cheng, Chi-Tung|Jung, Shih-Ming|Huang, Shih-Chiang|Chang, Ting-Wei|Jan, Yi-Yin|Tzeng, Cheng-Hwai|Chao, Ta-Chung|Chen, Yeng-Yang|Yang, Ching-Yao|Ho, Ching-Liang|Fletcher, Jonathan A
PMID: 22588468
Journal: Pathol Int. 2012 Jul;62(7):477-84.
Title: Detection of kinase amplifications in gastric cancer archives using fluorescence in situ hybridization.
Author: Kiyose, Shin-ichiro|Nagura, Kiyoko|Tao, Hong|Igarashi, Hisaki|Yamada, Hidetaka|Goto, Masanori|Maeda, Matsuyoshi|Kurabe, Nobuya|Suzuki, Masaya|Tsuboi, Masaru|Kahyo, Tomoaki|Shinmura, Kazuya|Hattori, Naohiko|Sugimura, Haruhiko
PMID: 22691185
Journal: Am J Transl Res. 2013 Dec 1;6(1):28-42. eCollection 2013.
Title: Transcriptomic changes induced by mycophenolic acid in gastric cancer cells.
Author: Dun, Boying|Sharma, Ashok|Xu, Heng|Liu, Haitao|Bai, Shan|Zeng, Lingwen|She, Jin-Xiong
PMID: 24349619
Journal: Gastroenterology. 2013 Dec;145(6):1312-22.e1-8.
Title: Aurora kinase A promotes inflammation and tumorigenesis in mice and human gastric neoplasia.
Author: Katsha, Ahmed|Soutto, Mohammed|Sehdev, Vikas|Peng, Dunfa|Washington, M Kay|Piazuelo, M Blanca|Tantawy, Mohammed N|Manning, H Charles|Lu, Pengcheng|Shyr, Yu|Ecsedy, Jeffrey|Belkhiri, Abbes|El-Rifai, Wael
PMID: 23993973
Journal: PLoS One. 2013 Jun 5;8(6):e65264.
Title: Small molecule R1498 as a well-tolerated and orally active kinase inhibitor for hepatocellular carcinoma and gastric cancer treatment via targeting angiogenesis and mitosis pathways.
Author: Zhang, Chao|Wu, Xihan|Zhang, Meifang|Zhu, Liangcheng|Zhao, Rong|Xu, Danqing|Lin, Zhaohu|Liang, Chungen|Chen, Taiping|Chen, Li|Ren, Yi|Zhang, Joe|Qin, Ning|Zhang, Xiongwen
PMID: 23755206
Journal: J Surg Oncol. 2014 Mar;109(3):189-97.
Title: TNK2 gene amplification is a novel predictor of a poor prognosis in patients with gastric cancer.
Author: Shinmura, Kazuya|Kiyose, Shinichiro|Nagura, Kiyoko|Igarashi, Hisaki|Inoue, Yusuke|Nakamura, Satoki|Maeda, Matsuyoshi|Baba, Megumi|Konno, Hiroyuki|Sugimura, Haruhiko
PMID: 24178904
Journal: Clin Cancer Res. 2014 Jan 1;20(1):76-86.
Title: HDM2 regulation by AURKA promotes cell survival in gastric cancer.
Author: Sehdev, Vikas|Katsha, Ahmed|Arras, Janet|Peng, Dunfa|Soutto, Mohammed|Ecsedy, Jeffrey|Zaika, Alexander|Belkhiri, Abbes|El-Rifai, Wael
PMID: 24240108
Journal: J Pediatr Surg. 2014 Jan;49(1):159-65.
Title: Targeting Aurora kinase-A downregulates cell proliferation and angiogenesis in neuroblastoma.
Author: Romain, Carmelle|Paul, Pritha|Kim, Kwang Woon|Lee, Sora|Qiao, Jingbo|Chung, Dai H
PMID: 24439602
Journal: Turk J Med Sci. 2014;44(3):461-70.
Title: Detection of kinase amplifications in gastric adenocarcinomas.
Author: Ozdemiri, Muhsin|Oznur, Murat|Ciftci, Evrim|Durak Aras, Beyhan|Aslan, Huseyin|Saygili, Hande|Oner, Kevser Setenay|Erkasap, Serdar Mustafa|Ozakyol, Aysegiil|Pasaoglu, Ozgiil|Cilingir, Oguz|Artan, Sevilhan
PMID: 25558650
Journal: Drug Des Devel Ther. 2015 Jan 14;9:487-508.
Title: Inhibition of mitotic Aurora kinase A by alisertib induces apoptosis and autophagy of human gastric cancer AGS and NCI-N78 cells.
Author: Yuan, Chun-Xiu|Zhou, Zhi-Wei|Yang, Yin-Xue|He, Zhi-Xu|Zhang, Xueji|Wang, Dong|Yang, Tianxing|Wang, Ning-Ju|Zhao, Ruan Jin|Zhou, Shu-Feng
PMID: 25609923
Journal: Clin Cancer Res. 2015 Feb 1;21(3):661.
Title: Correction: HDM2 Regulation by AURKA Promotes Cell Survival in Gastric Cancer.
Author:
PMID: 25646184
Journal: BMC Cancer. 2015 Nov 25;15:935.
Title: Osteoprotegerin secreted by inflammatory and invasive breast cancer cells induces aneuploidy, cell proliferation and angiogenesis.
Author: Goswami, Sudeshna|Sharma-Walia, Neelam
PMID: 26608463
Journal: IUBMB Life. 2016 Aug;68(8):634-44.
Title: Association of the AURKA and AURKC gene polymorphisms with an increased risk of gastric cancer.
Author: Mesic, Aner|Rogar, Marija|Hudler, Petra|Juvan, Robert|Komel, Radovan
PMID: 27270838
Journal: Oncotarget. 2016 May 31;7(22):33152-64.
Title: AURKA induces EMT by regulating histone modification through Wnt/beta-catenin and PI3K/Akt signaling pathway in gastric cancer.
Author: Liu, Xi|Li, Zhaoxia|Song, Yue|Wang, Rui|Han, Lei|Wang, Qixue|Jiang, Kui|Kang, Chunsheng|Zhang, Qingyu
PMID: 27121204
Journal: Cancer Med. 2016 Mar;5(3):516-26.
Title: Expression of aurora kinase A correlates with the Wnt-modulator RACGAP1 in gastric cancer.
Author: Bornschein, Jan|Nielitz, Jessica|Drozdov, Ignat|Selgrad, Michael|Wex, Thomas|Jechorek, Doerthe|Link, Alexander|Vieth, Michael|Malfertheiner, Peter
PMID: 26778597
Journal: Oncogenesis. 2017 Feb 20;6(2):e298.
Title: Aurora kinase A regulates Survivin stability through targeting FBXL7 in gastric cancer drug resistance and prognosis.
Author: Kamran, M|Long, Z-J|Xu, D|Lv, S-S|Liu, B|Wang, C-L|Xu, J|Lam, E W-F|Liu, Q
PMID: 28218735
Journal: Int J Oncol. 2017 Apr;50(4):1116-1126.
Title: UBE2C induces EMT through Wnt/betacatenin and PI3K/Akt signaling pathways by regulating phosphorylation levels of Aurora-A.
Author: Wang, Rui|Song, Yue|Liu, Xi|Wang, Qixue|Wang, Yunfei|Li, Liwei|Kang, Chunsheng|Zhang, Qingyu
PMID: 28260026
Journal: Mol Oncol. 2017 Aug;11(8):981-995.
Title: Cisplatin-resistant cancer cells are sensitive to Aurora kinase A inhibition by alisertib.
Author: Wang, Lihong|Arras, Janet|Katsha, Ahmed|Hamdan, Saif|Belkhiri, Abbes|Ecsedy, Jeffrey|El-Rifai, Wael
PMID: 28417568
Journal: Environ Mol Mutagen. 2017 Dec;58(9):701-711.
Title: Single nucleotide polymorphisms rs911160 in AURKA and rs2289590 in AURKB mitotic checkpoint genes contribute to gastric cancer susceptibility.
Author: Mesic, Aner|Markocic, Ela|Rogar, Marija|Juvan, Robert|Hudler, Petra|Komel, Radovan
PMID: 28843004
Journal: Oncotarget. 2017 Aug 10;8(43):74479-74493.
Title: FAM83D, a microtubule-associated protein, promotes tumor growth and progression of human gastric cancer.
Author: Huang, Minlu|Ma, Xinjie|Shi, Hongpeng|Hu, Lei|Fan, Zhiyuan|Pang, Li|Zhu, Fan|Yang, Xiao|Xu, Wei|Liu, Binya|Zhu, Zhenggang|Li, Chen
PMID: 29088801
Journal: Int J Mol Med. 2018 Jun;41(6):3629-3641.
Title: Low expression of PTEN is essential for maintenance of a malignant state in human gastric adenocarcinoma via upregulation of pAURKA mediated by activation of AURKA.
Author: Li, Liwei|Song, Yue|Liu, Qing|Liu, Xi|Wang, Rui|Kang, Chunsheng|Zhang, Qingyu
PMID: 29512701
Journal: Cell Death Dis. 2018 Jul 16;9(8):781.
Title: Suppression of AURKA alleviates p27 inhibition on Bax cleavage and induces more intensive apoptosis in gastric cancer.
Author: Hou, Daisen|Che, Zhihui|Chen, Ping|Zhang, Wenli|Chu, Yiwei|Yang, Dongqin|Liu, Jie
PMID: 30013101
Journal: Oncol Lett. 2018 Sep;16(3):3070-3082.
Title: Role of PLK1 signaling pathway genes in gastrointestinal stromal tumors.
Author: Chen, Jen-Shi|Yeh, Chun-Nan|Cheng, Chi-Tung|Yen, Chueh-Chuan|Chen, Yen-Yang|Huang, Shih-Chiang|Chiang, Kun-Chun|Yeh, Ta-Sen|Chen, San-Chi|Chao, Ta-Chung|Yang, Muh-Hwa|Chao, Yee
PMID: 30127898
Journal: Front Physiol. 2018 Aug 17;9:1124.
Title: The Association Between AURKA Gene rs2273535 Polymorphism and Gastric Cancer Risk in a Chinese Population.
Author: Zhou, Xiaoyan|Wang, Pengli|Zhao, Hui
PMID: 30174615
Journal: Mol Biol Rep. 2018 Sep 24. pii: 10.1007/s11033-018-4389-z.
Title: Expression profiles of histone modification genes in gastric cancer progression.
Author: Orenay-Boyacioglu, Seda|Kasap, Elmas|Gerceker, Emre|Yuceyar, Hakan|Demirci, Ufuk|Bilgic, Fahri|Korkmaz, Mehmet
PMID: 30250993