Literatures

Primary Site >> Colorectal Cancer

Gene >> AURKA

1.
Journal:	EMBO J. 1998 Jun 1;17(11):3052-65.
Title:	A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers.
Author:	Bischoff, J R\|Anderson, L\|Zhu, Y\|Mossie, K\|Ng, L\|Souza, B\|Schryver, B\|Flanagan, P\|Clairvoyant, F\|Ginther, C\|Chan, C S\|Novotny, M\|Slamon, D J\|Plowman, G D
PMID:	9606188

2.
Journal:	Nat Genet. 1998 Oct;20(2):189-93.
Title:	Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation.
Author:	Zhou, H\|Kuang, J\|Zhong, L\|Kuo, W L\|Gray, J W\|Sahin, A\|Brinkley, B R\|Sen, S
PMID:	9771714

3.
Journal:	Mol Cancer Ther. 2003 Mar;2(3):283-94.
Title:	Targeting aurora2 kinase in oncogenesis: a structural bioinformatics approach to target validation and rational drug design.
Author:	Vankayalapati, Hariprasad\|Bearss, David J\|Saldanha, Jose W\|Munoz, Ruben M\|Rojanala, Sangeeta\|Von Hoff, Daniel D\|Mahadevan, Daruka
PMID:	12657723

4.
Journal:	Curr Med Chem Anticancer Agents. 2003 Jan;3(1):25-34.
Title:	Structure-based design of novel anti-cancer agents targeting aurora kinases.
Author:	Mahadevan, Daruka\|Bearss, David J\|Vankayalapati, Hariprasad
PMID:	12678912

5.
Journal:	Cancer Sci. 2003 Feb;94(2):148-52.
Title:	Polo-like kinase 1 (PLK1) is overexpressed in primary colorectal cancers.
Author:	Takahashi, Takao\|Sano, Bun\|Nagata, Takayasu\|Kato, Hiroki\|Sugiyama, Yasuyuki\|Kunieda, Katsuyuki\|Kimura, Masashi\|Okano, Yukio\|Saji, Shigetoyo
PMID:	12708489

6.
Journal:	Nat Genet. 2003 Aug;34(4):403-12.
Title:	Identification of Stk6/STK15 as a candidate low-penetrance tumor-susceptibility gene in mouse and human.
Author:	Ewart-Toland, Amanda\|Briassouli, Paraskevi\|de Koning, John P\|Mao, Jian-Hua\|Yuan, Jinwei\|Chan, Florence\|MacCarthy-Morrogh, Lucy\|Ponder, Bruce A J\|Nagase, Hiroki\|Burn, John\|Ball, Sarah\|Almeida, Maria\|Linardopoulos, Spiros\|Balmain, Allan
PMID:	12881723

7.
Journal:	Oncol Rep. 2003 Sep-Oct;10(5):1275-9.
Title:	The putative serine/threonine kinase gene STK15 on chromosome 20q13.2 is amplified in human gliomas.
Author:	Reichardt, Wilfried\|Jung, Volker\|Brunner, Christian\|Klein, Alexandra\|Wemmert, Silke\|Romeike, Bernd F M\|Zang, Klaus D\|Urbschat, Steffi
PMID:	12883693

8.
Journal:	Hepatogastroenterology. 2003 Nov-Dec;50(54):1857-63.
Title:	Chromosome arm 20q gains and other genomic alterations in esophageal squamous cell carcinoma, as analyzed by comparative genomic hybridization and fluorescence in situ hybridization.
Author:	Fujita, Yoshifumi\|Sakakura, Chouhei\|Shimomura, Katsumi\|Nakanishi, Masayoshi\|Yasuoka, Rie\|Aragane, Hideki\|Hagiwara, Akeo\|Abe, Tatsuo\|Inazawa, Johji\|Yamagishi, Hisakazu
PMID:	14696419

9.
Journal:	Cancer Metastasis Rev. 2004 Jan-Jun;23(1-2):11-27.
Title:	Genomic instability and colon cancer.
Author:	Grady, William M
PMID:	15000146

10.
Journal:	Carcinogenesis. 2005 Aug;26(8):1368-73. Epub 2005 Mar 31.
Title:	Aurora-A/STK15 T+91A is a general low penetrance cancer susceptibility gene: a meta-analysis of multiple cancer types.
Author:	Ewart-Toland, Amanda\|Dai, Qi\|Gao, Yu-Tang\|Nagase, Hiroki\|Dunlop, Malcolm G\|Farrington, Susan M\|Barnetson, Rebecca A\|Anton-Culver, Hoda\|Peel, David\|Ziogas, Argyrios\|Lin, Dongxin\|Miao, Xiaoping\|Sun, Tong\|Ostrander, Elaine A\|Stanford, Janet L\|Langlois, Marie
PMID:	15802297

11.
Journal:	Int J Cancer. 2006 Jan 15;118(2):505-8.
Title:	Preferential amplification of AURKA 91A (Ile31) in familial colorectal cancers.
Author:	Hienonen, Tuija\|Salovaara, Reijo\|Mecklin, Jukka-Pekka\|Jarvinen, Heikki\|Karhu, Auli\|Aaltonen, Lauri A
PMID:	16049965

12.
Journal:	J Pathol. 2006 Mar;208(4):462-72.
Title:	Centrosome-, chromosomal-passenger- and cell-cycle-associated mRNAs are differentially regulated in the development of sporadic colorectal cancer.
Author:	Gerlach, Ulrike\|Kayser, Gian\|Walch, Axel\|Hopt, Ulrich\|Schulte-Monting, Jurgen\|Werner, Martin\|Lassmann, Silke
PMID:	16402339

13.
Journal:	Cell Cycle. 2006 Apr;5(8):818-23.
Title:	Chromosomal instability, colorectal cancer and taxane resistance.
Author:	Swanton, Charles\|Tomlinson, Ian\|Downward, Julian
PMID:	16628000

14.
Journal:	Zhonghua Zhong Liu Za Zhi. 2006 Jan;28(1):43-6.
Title:	[Association between genetic polymorphism in STK15 and risk of colorectal cancer in a Chinese population].
Author:	Zhang, Wen-jie\|Miao, Xiao-ping\|Sun, Tong\|Zhang, Xue-mei\|Qu, Shi-ning\|Tan, Wen\|Xiong, Ping\|Zheng, Rong\|Lin, Dong-xin
PMID:	16737620

15.
Journal:	Br J Cancer. 2006 Oct 23;95(8):1047-9. Epub 2006 Sep 26.
Title:	Case-control, kin-cohort and meta-analyses provide no support for STK15 F31I as a low penetrance colorectal cancer allele.
Author:	Webb, E L\|Rudd, M F\|Houlston, R S
PMID:	17003782

16.
Journal:	Mol Carcinog. 2007 Apr;46(4):249-56.
Title:	Association between Aurora-A kinase polymorphisms and age of onset of hereditary nonpolyposis colorectal cancer in a Caucasian population.
Author:	Chen, Jinyun\|Sen, Subrata\|Amos, Christopher I\|Wei, Chongjuan\|Jones, J Shawn\|Lynch, Patrick\|Frazier, Marsha L
PMID:	17219423

17.
Journal:	Gastroenterology. 2007 Feb;132(2):645-53.
Title:	A simple method for the routine detection of somatic quantitative genetic alterations in colorectal cancer.
Author:	Killian, Audrey\|Di Fiore, Frederic\|Le Pessot, Florence\|Blanchard, France\|Lamy, Aude\|Raux, Gregory\|Flaman, Jean-Michel\|Paillot, Bernard\|Michel, Pierre\|Sabourin, Jean-Christophe\|Tuech, Jean-Jacques\|Michot, Francis\|Kerckaert, Jean-Pierre\|Sesboue, Richard\|Fre
PMID:	17258723

18.
Journal:	Biochem Biophys Res Commun. 2007 Mar 23;354(4):992-8.
Title:	The FBXW7 beta-form is suppressed in human glioma cells.
Author:	Gu, Zhaodi\|Inomata, Kenichi\|Ishizawa, Kota\|Horii, Akira
PMID:	17274947

19.
Journal:	J Clin Pathol. 2007 Dec;60(12):1403-8.
Title:	Spindle proteins Aurora A and BUB1B, but not Mad2, are aberrantly expressed in dysplastic mucosa of patients with longstanding ulcerative colitis.
Author:	Burum-Auensen, E\|Deangelis, P M\|Schjolberg, A R\|Roislien, Jo\|Andersen, S N\|Clausen, O P F
PMID:	17322345

20.
Journal:	Cancer Biol Ther. 2007 Apr;6(4):525-33.
Title:	High copy amplification of the Aurora-A gene is associated with chromosomal instability phenotype in human colorectal cancers.
Author:	Nishida, Naoshi\|Nagasaka, Takeshi\|Kashiwagi, Kazuhiro\|Boland, C Richard\|Goel, Ajay
PMID:	17457043

21.
Journal:	Ann Oncol. 2007 Jun;18 Suppl 6:vi47-52.
Title:	The role of Aurora-A inhibitors in cancer therapy.
Author:	Agnese, V\|Bazan, V\|Fiorentino, F P\|Fanale, D\|Badalamenti, G\|Colucci, G\|Adamo, V\|Santini, D\|Russo, A
PMID:	17591831

22.
Journal:	BMC Cancer. 2007 Nov 13;7:212.
Title:	Simultaneous Aurora-A/STK15 overexpression and centrosome amplification induce chromosomal instability in tumour cells with a MIN phenotype.
Author:	Lentini, Laura\|Amato, Angela\|Schillaci, Tiziana\|Di Leonardo, Aldo
PMID:	17999753

23.
Journal:	Cell Cycle. 2007 Dec 15;6(24):3114-31.
Title:	The cyclin-dependent kinase inhibitor seliciclib (R-roscovitine; CYC202) decreases the expression of mitotic control genes and prevents entry into mitosis.
Author:	Whittaker, Steven R\|Te Poele, Robert H\|Chan, Florence\|Linardopoulos, Spiros\|Walton, Michael I\|Garrett, Michelle D\|Workman, Paul
PMID:	18075315

24.
Journal:	Int J Cancer. 2008 Mar 15;122(6):1273-7.
Title:	Aurora-A and Cyclin D1 polymorphisms and the age of onset of colorectal cancer in hereditary nonpolyposis colorectal cancer.
Author:	Talseth, Bente A\|Ashton, Katie A\|Meldrum, Cliff\|Suchy, Janina\|Kurzawski, Grzegorz\|Lubinski, Jan\|Scott, Rodney J
PMID:	18027856

25.
Journal:	Oncol Res. 2008;17(3):115-25.
Title:	Aurora-A transcriptional silencing and vincristine treatment show a synergistic effect in human tumor cells.
Author:	Lentini, Laura\|Amato, Angela\|Schillaci, Tiziana\|Insalaco, Lavinia\|Di Leonardo, Aldo
PMID:	18669163

26.
Journal:	Cell Prolif. 2008 Aug;41(4):645-59.
Title:	Reduced level of the spindle checkpoint protein BUB1B is associated with aneuploidy in colorectal cancers.
Author:	Burum-Auensen, E\|DeAngelis, P M\|Schjolberg, A R\|Roislien, J\|Mjaland, O\|Clausen, O P F
PMID:	18699967

27.
Journal:	Cancer Inform. 2008;6:147-64. Epub 2008 Mar 26.
Title:	Chromosome 20q amplification regulates in vitro response to Kinesin-5 inhibitor.
Author:	Jackson, Aimee L\|Mao, Mao\|Kobayashi, Sumire\|Ward, Teresa\|Biery, Matthew\|Dai, Hongyue\|Bartz, Steven R\|Linsley, Peter S
PMID:	19259408

28.
Journal:	Gut. 2009 Jan;58(1):79-89.
Title:	Multiple putative oncogenes at the chromosome 20q amplicon contribute to colorectal adenoma to carcinoma progression.
Author:	Carvalho, B\|Postma, C\|Mongera, S\|Hopmans, E\|Diskin, S\|van de Wiel, M A\|van Criekinge, W\|Thas, O\|Matthai, A\|Cuesta, M A\|Terhaar Sive Droste, J S\|Craanen, M\|Schrock, E\|Ylstra, B\|Meijer, G A
PMID:	18829976

29.
Journal:	J Clin Pathol. 2009 Sep;62(9):777-85.
Title:	Molecular pathology of endometrial carcinoma: practical aspects from the diagnostic and therapeutic viewpoints.
Author:	Llobet, D\|Pallares, J\|Yeramian, A\|Santacana, M\|Eritja, N\|Velasco, A\|Dolcet, X\|Matias-Guiu, X
PMID:	18977806

30.
Journal:	Chembiochem. 2009 Feb 13;10(3):464-78.
Title:	Development and biological evaluation of a novel aurora A kinase inhibitor.
Author:	Sardon, Teresa\|Cottin, Thomas\|Xu, Jing\|Giannis, Athanassios\|Vernos, Isabelle
PMID:	19199284

31.
Journal:	Proc Natl Acad Sci U S A. 2009 Apr 28;106(17):7131-6.
Title:	Association of survival and disease progression with chromosomal instability: a genomic exploration of colorectal cancer.
Author:	Sheffer, Michal\|Bacolod, Manny D\|Zuk, Or\|Giardina, Sarah F\|Pincas, Hanna\|Barany, Francis\|Paty, Philip B\|Gerald, William L\|Notterman, Daniel A\|Domany, Eytan
PMID:	19359472

32.
Journal:	Neoplasia. 2009 May;11(5):418-25.
Title:	Aurora-A expression is independently associated with chromosomal instability in colorectal cancer.
Author:	Baba, Yoshifumi\|Nosho, Katsuhiko\|Shima, Kaori\|Irahara, Natsumi\|Kure, Shoko\|Toyoda, Saori\|Kirkner, Gregory J\|Goel, Ajay\|Fuchs, Charles S\|Ogino, Shuji
PMID:	19412426

33.
Journal:	Mol Cancer Ther. 2009 Jul;8(7):2046-56.
Title:	Determinants for the efficiency of anticancer drugs targeting either Aurora-A or Aurora-B kinases in human colon carcinoma cells.
Author:	Kaestner, Phillip\|Stolz, Ailine\|Bastians, Holger
PMID:	19584233

34.
Journal:	Mod Pathol. 2009 Oct;22(10):1385-97.
Title:	Aurora A is differentially expressed and regulated in chromosomal and microsatellite instable sporadic colorectal cancers.
Author:	Lassmann, Silke\|Danciu, Mihai\|Muller, Matthias\|Weis, Roland\|Makowiec, Frank\|Schulte-Monting, Jurgen\|Hopt, Ulrich T\|Werner, Martin
PMID:	19648887

35.
Journal:	J Clin Invest. 2009 Sep;119(9):2714-24.
Title:	Deficiencies in Chfr and Mlh1 synergistically enhance tumor susceptibility in mice.
Author:	Fu, Zheng\|Regan, Kevin\|Zhang, Lizhi\|Muders, Michael H\|Thibodeau, Stephen N\|French, Amy\|Wu, Yanhong\|Kaufmann, Scott H\|Lingle, Wilma L\|Chen, Junjie\|Tindall, Donald J
PMID:	19690386

36.
Journal:	Cancer Causes Control. 2009 Nov;20(9):1769-77.
Title:	Genetic variants in the cell cycle control pathways contribute to early onset colorectal cancer in Lynch syndrome.
Author:	Chen, Jinyun\|Etzel, Carol J\|Amos, Christopher I\|Zhang, Qing\|Viscofsky, Nancy\|Lindor, Noralane M\|Lynch, Patrick M\|Frazier, Marsha L
PMID:	19690970

37.
Journal:	Environ Mol Mutagen. 2009 Oct;50(8):672-96.
Title:	Nucleation capacity and presence of centrioles define a distinct category of centrosome abnormalities that induces multipolar mitoses in cancer cells.
Author:	Difilippantonio, Michael J\|Ghadimi, B Michael\|Howard, Tamara\|Camps, Jordi\|Nguyen, Quang Tri\|Ferris, Douglas K\|Sackett, Dan L\|Ried, Thomas
PMID:	19768832

38.
Journal:	J Biol Chem. 2009 Nov 27;284(48):33177-84.
Title:	A cancer-associated aurora A mutant is mislocalized and misregulated due to loss of interaction with TPX2.
Author:	Bibby, Rachel Ann\|Tang, Chan\|Faisal, Amir\|Drosopoulos, Konstantinos\|Lubbe, Steven\|Houlston, Richard\|Bayliss, Richard\|Linardopoulos, Spiros
PMID:	19801554

39.
Journal:	BMC Cancer. 2009 Dec 12;9:435.
Title:	Aurora-A overexpression enhances cell-aggregation of Ha-ras transformants through the MEK/ERK signaling pathway.
Author:	Tseng, Ya-Shih\|Lee, Jenq-Chang\|Huang, Chi-Ying F\|Liu, Hsiao-Sheng
PMID:	20003375

40.
Journal:	Anticancer Res. 2009 Nov;29(11):4381-7.
Title:	Aneuploidy is associated with TP53 expression but not with BRCA1 or TERT expression in sporadic colorectal cancer.
Author:	Schjolberg, Aasa R\|Clausen, Ole Petter F\|Burum-Auensen, Espen\|De Angelis, Paula M
PMID:	20032382

41.
Journal:	Cancer Chemother Pharmacol. 2010 Mar;65(4):707-17.
Title:	SNS-314, a pan-Aurora kinase inhibitor, shows potent anti-tumor activity and dosing flexibility in vivo.
Author:	Arbitrario, Jennifer P\|Belmont, Brian J\|Evanchik, Marc J\|Flanagan, W Michael\|Fucini, Raymond V\|Hansen, Stig K\|Harris, Shannon O\|Hashash, Ahmad\|Hoch, Ute\|Hogan, Jennifer N\|Howlett, Anthony R\|Jacobs, Jeffrey W\|Lam, Joni W\|Ritchie, Sean C\|Romanowski, Michael
PMID:	19649632

42.
Journal:	Biochem Pharmacol. 2010 Jan 15;79(2):122-9.
Title:	Aurora kinase inhibitor ZM447439 induces apoptosis via mitochondrial pathways.
Author:	Li, Minglun\|Jung, Anke\|Ganswindt, Ute\|Marini, Patrizia\|Friedl, Anna\|Daniel, Peter T\|Lauber, Kirsten\|Jendrossek, Verena\|Belka, Claus
PMID:	19686703

43.
Journal:	J Cell Mol Med. 2010 Jun;14(6B):1520-31.
Title:	Translational up-regulation of Aurora-A in EGFR-overexpressed cancer.
Author:	Lai, Chien-Hsien\|Tseng, Joseph T\|Lee, Yi-Chao\|Chen, Ying-Ju\|Lee, Jeng-Chang\|Lin, Bo-Wen\|Huang, Tai-Chien\|Liu, Yao-Wen\|Leu, Tzeng-Horng\|Liu, Yi-Wen\|Chen, Ya-Ping\|Chang, Wen-Chang\|Hung, Liang-Yi
PMID:	19799648

44.
Journal:	Cancer Res. 2010 Jan 15;70(2):824-31.
Title:	HEF1 is a crucial mediator of the proliferative effects of prostaglandin E(2) on colon cancer cells.
Author:	Xia, Dianren\|Holla, Vijaykumar R\|Wang, Dingzhi\|Menter, David G\|DuBois, Raymond N
PMID:	20068165

45.
Journal:	Tumour Biol. 2010 Apr;31(2):89-96.
Title:	Identification of key genes for carcinogenic pathways associated with colorectal adenoma-to-carcinoma progression.
Author:	Sillars-Hardebol, Anke H\|Carvalho, Beatriz\|de Wit, Meike\|Postma, Cindy\|Delis-van Diemen, Pien M\|Mongera, Sandra\|Ylstra, Bauke\|van de Wiel, Mark A\|Meijer, Gerrit A\|Fijneman, Remond J A
PMID:	20358421

46.
Journal:	J Med Chem. 2010 May 27;53(10):3973-4001.
Title:	Discovery of GSK1070916, a potent and selective inhibitor of Aurora B/C kinase.
Author:	Adams, Nicholas D\|Adams, Jerry L\|Burgess, Joelle L\|Chaudhari, Amita M\|Copeland, Robert A\|Donatelli, Carla A\|Drewry, David H\|Fisher, Kelly E\|Hamajima, Toshihiro\|Hardwicke, Mary Ann\|Huffman, William F\|Koretke-Brown, Kristin K\|Lai, Zhihong V\|McDonald, Octerl
PMID:	20420387

47.
Journal:	Clin Cancer Res. 2010 Jun 15;16(12):3171-81.
Title:	Aurora kinase A promotes ovarian tumorigenesis through dysregulation of the cell cycle and suppression of BRCA2.
Author:	Yang, Gong\|Chang, Bin\|Yang, Fan\|Guo, Xiaoqing\|Cai, Kathy Qi\|Xiao, Xue Sherry\|Wang, Huamin\|Sen, Subrata\|Hung, Mien-Chie\|Mills, Gordon B\|Chang, Sandy\|Multani, Asha S\|Mercado-Uribe, Imelda\|Liu, Jinsong
PMID:	20423983

48.
Journal:	Cancer Res. 2010 Jun 1;70(11):4655-65.
Title:	Aurora-a is essential for the tumorigenic capacity and chemoresistance of colorectal cancer stem cells.
Author:	Cammareri, Patrizia\|Scopelliti, Alessandro\|Todaro, Matilde\|Eterno, Vincenzo\|Francescangeli, Federica\|Moyer, Mary Pat\|Agrusa, Antonino\|Dieli, Francesco\|Zeuner, Ann\|Stassi, Giorgio
PMID:	20460511

49.
Journal:	Acta Biochim Biophys Sin (Shanghai). 2010 Nov;42(11):834-8.
Title:	Copy number increase of aurora kinase A in colorectal cancers: a correlation with tumor progression.
Author:	Zhang, Chao\|Fang, Zhengyu\|Xiong, Yi\|Li, Jiana\|Liu, Li\|Li, Manhui\|Zhang, Wei\|Wan, Jun
PMID:	20929925

50.
Journal:	Pharmacogenomics J. 2011 Apr;11(2):93-9.
Title:	Pharmacogenetic profiling of Aurora kinase B is associated with overall survival in metastatic colorectal cancer.
Author:	Pohl, A\|Azuma, M\|Zhang, W\|Yang, D\|Ning, Y\|Winder, T\|Danenberg, K\|Lenz, H-J
PMID:	20368716

51.
Journal:	Int J Cancer. 2011 Feb 1;128(3):691-701.
Title:	Downregulation of survivin and aurora A by histone deacetylase and RAS inhibitors: a new drug combination for cancer therapy.
Author:	Biran, Anat\|Brownstein, Michael\|Haklai, Ronit\|Kloog, Yoel
PMID:	20473860

52.
Journal:	Bioorg Med Chem Lett. 2011 Sep 15;21(18):5633-7.
Title:	Design, synthesis, and biological evaluation of pyrazolopyrimidine-sulfonamides as potent multiple-mitotic kinase (MMK) inhibitors (part I).
Author:	Zhang, Lin\|Fan, Junhua\|Chong, Jer-Hong\|Cesena, Angela\|Tam, Betty Y Y\|Gilson, Charles\|Boykin, Christina\|Wang, Deping\|Aivazian, Dikran\|Marcotte, Doug\|Xiao, Guangqing\|Le Brazidec, Jean-Yves\|Piao, Jinhua\|Lundgren, Karen\|Hong, Kevin\|Vu, Khang\|Nguyen, Khanh\|Gan
PMID:	21798738

53.
Journal:	Cancer Biol Ther. 2011 Dec 15;12(12):1059-68.
Title:	Aurora A mediates cross-talk between N- and C-terminal post-translational modifications of p53.
Author:	Warnock, Lorna Jane\|Raines, Sally Anne\|Milner, Jo
PMID:	22157150

54.
Journal:	Oncogene. 2012 Mar 8;31(10):1217-27.
Title:	Dual inhibition of SRC and Aurora kinases induces postmitotic attachment defects and cell death.
Author:	Ratushny, V\|Pathak, H B\|Beeharry, N\|Tikhmyanova, N\|Xiao, F\|Li, T\|Litwin, S\|Connolly, D C\|Yen, T J\|Weiner, L M\|Godwin, A K\|Golemis, E A
PMID:	21785464

55.
Journal:	Exp Mol Pathol. 2012 Feb;92(1):27-32.
Title:	Efficiency of G2/M-related tumor-associated antigen-targeting cancer immunotherapy depends on antigen expression in the cancer stem-like population.
Author:	Mori, Takashi\|Nishizawa, Satoshi\|Hirohashi, Yoshihiko\|Torigoe, Toshihiko\|Tamura, Yasuaki\|Takahashi, Akari\|Kochin, Vitaly\|Fujii, Reona\|Kondo, Toru\|Greene, Mark I\|Hara, Isao\|Sato, Noriyuki
PMID:	22001602

56.
Journal:	J Pathol. 2012 Feb;226(3):442-50.
Title:	BCL2L1 has a functional role in colorectal cancer and its protein expression is associated with chromosome 20q gain.
Author:	Sillars-Hardebol, Anke H\|Carvalho, Beatriz\|Belien, Jeroen Am\|de Wit, Meike\|Delis-van Diemen, Pien M\|Tijssen, Marianne\|van de Wiel, Mark A\|Ponten, Fredrik\|Fijneman, Remond Ja\|Meijer, Gerrit A
PMID:	22009326

57.
Journal:	Gut. 2012 Nov;61(11):1568-75. Epub 2011 Dec 29.
Title:	TPX2 and AURKA promote 20q amplicon-driven colorectal adenoma to carcinoma progression.
Author:	Sillars-Hardebol, Anke H\|Carvalho, Beatriz\|Tijssen, Marianne\|Belien, Jeroen A M\|de Wit, Meike\|Delis-van Diemen, Pien M\|Ponten, Fredrik\|van de Wiel, Mark A\|Fijneman, Remond J A\|Meijer, Gerrit A
PMID:	22207630

58.
Journal:	Mol Cancer Ther. 2012 Mar;11(3):710-9.
Title:	An integrated genomic approach to identify predictive biomarkers of response to the aurora kinase inhibitor PF-03814735.
Author:	Hook, Kenneth E\|Garza, Scott J\|Lira, Maruja E\|Ching, Keith A\|Lee, Nathan V\|Cao, Joan\|Yuan, Jing\|Ye, Jingjing\|Ozeck, Mark\|Shi, Stephanie T\|Zheng, Xianxian\|Rejto, Paul A\|Kan, Julie L C\|Christensen, James G\|Pavlicek, Adam
PMID:	22222631

59.
Journal:	Biochem Pharmacol. 2012 May 1;83(9):1217-28.
Title:	Acute sensitization of colon cancer cells to inflammatory cytokines by prophase arrest.
Author:	Kuratnik, Anton\|Senapati, Virginia E\|Verma, Rajeev\|Mellone, Barbara G\|Vella, Anthony T\|Giardina, Charles
PMID:	22306067

60.
Journal:	Ann Surg Oncol. 2012 Jul;19 Suppl 3:S682-92.
Title:	Cell cycle proteins predict recurrence in stage II and III colon cancer.
Author:	Belt, Eric J Th\|Brosens, Rebecca P M\|Delis-van Diemen, Pien M\|Bril, Herman\|Tijssen, Marianne\|van Essen, Dirk F\|Heymans, Martijn W\|Belien, Jeroen A M\|Stockmann, Hein B A C\|Meijer, Sybren\|Meijer, Gerrit A
PMID:	22311118

61.
Journal:	J Med Chem. 2012 Apr 12;55(7):3250-60.
Title:	Discovery of highly potent and selective pan-Aurora kinase inhibitors with enhanced in vivo antitumor therapeutic index.
Author:	Liu, Gang\|Abraham, Sunny\|Tran, Lan\|Vickers, Troy D\|Xu, Shimin\|Hadd, Michael J\|Quiambao, Sheena\|Holladay, Mark W\|Hua, Helen\|Ford Pulido, Julia M\|Gunawardane, Ruwanthi N\|Davis, Mindy I\|Eichelberger, Shawn R\|Apuy, Julius L\|Gitnick, Dana\|Gardner, Michael F\|Ja
PMID:	22380736

62.
Journal:	Cell Cycle. 2012 Jun 1;11(11):2149-58.
Title:	Preferential killing of p53-deficient cancer cells by reversine.
Author:	Jemaa, Mohamed\|Galluzzi, Lorenzo\|Kepp, Oliver\|Boileve, Alice\|Lissa, Delphine\|Senovilla, Laura\|Harper, Francis\|Pierron, Gerard\|Berardinelli, Francesco\|Antoccia, Antonio\|Castedo, Maria\|Vitale, Ilio\|Kroemer, Guido
PMID:	22592527

63.
Journal:	Proc Natl Acad Sci U S A. 2013 May 7;110(19):E1779-87.
Title:	Aurora kinase inhibitors reveal mechanisms of HURP in nucleation of centrosomal and kinetochore microtubules.
Author:	Wu, Jiun-Ming\|Chen, Chiung-Tong\|Coumar, Mohane Selvaraj\|Lin, Wen-Hsin\|Chen, Zi-Jie\|Hsu, John T-A\|Peng, Yi-Hui\|Shiao, Hui-Yi\|Lin, Wen-Hsing\|Chu, Chang-Ying\|Wu, Jian-Sung\|Lin, Chih-Tsung\|Chen, Ching-Ping\|Hsueh, Ching-Cheng\|Chang, Kai-Yen\|Kao, Li-Pin\|Huang,
PMID:	23610398

64.
Journal:	Int J Biol Sci. 2013 Apr 29;9(4):403-11.
Title:	A novel aurora-A inhibitor, BPR1K0609S1, sensitizes colorectal tumor cells to 5-fluorofracil (5-FU) treatment.
Author:	Shionome, Yoshimi\|Lin, Wen-Hsing\|Shiao, Hui-Yi\|Hsieh, Hsing-Pang\|Hsu, John Tsu-An\|Ouchi, Toru
PMID:	23678290

65.
Journal:	Br J Cancer. 2013 Oct 29;109(9):2445-52.
Title:	Aurora kinase A (AURKA) expression in colorectal cancer liver metastasis is associated with poor prognosis.
Author:	Goos, J A C M\|Coupe, V M H\|Diosdado, B\|Delis-Van Diemen, P M\|Karga, C\|Belien, J A M\|Carvalho, B\|van den Tol, M P\|Verheul, H M W\|Geldof, A A\|Meijer, G A\|Hoekstra, O S\|Fijneman, R J A
PMID:	24104968

66.
Journal:	J Cancer Res Ther. 2013 Jul-Sep;9(3):467-70.
Title:	Expression profiling based on graph-clustering approach to determine colon cancer pathway.
Author:	Zhu, Xiao-qu\|Hu, Mei-lan\|Zhang, Feng\|Tao, Yu\|Wu, Chun-ming\|Lin, Shang-zhu\|He, Fu-le
PMID:	24125984

67.
Journal:	J Med Chem. 2013 Nov 27;56(22):9122-35.
Title:	Aurora isoform selectivity: design and synthesis of imidazo[4,5-b]pyridine derivatives as highly selective inhibitors of Aurora-A kinase in cells.
Author:	Bavetsias, Vassilios\|Faisal, Amir\|Crumpler, Simon\|Brown, Nathan\|Kosmopoulou, Magda\|Joshi, Amar\|Atrash, Butrus\|Perez-Fuertes, Yolanda\|Schmitt, Jessica A\|Boxall, Katherine J\|Burke, Rosemary\|Sun, Chongbo\|Avery, Sian\|Bush, Katherine\|Henley, Alan\|Raynaud, Flor
PMID:	24195668

68.
Journal:	Cancer Epidemiol. 2014 Apr;38(2):111-7.
Title:	STK15 rs2273535 polymorphism and cancer risk: a meta-analysis of 74,896 subjects.
Author:	Xu, Lei\|Zhou, Xin\|Jiang, Feng\|Xu, Lin\|Yin, Rong
PMID:	24252226

69.
Journal:	J Biol Chem. 2014 Jan 31;289(5):2978-91.
Title:	Novel piperazine-based compounds inhibit microtubule dynamics and sensitize colon cancer cells to tumor necrosis factor-induced apoptosis.
Author:	Chopra, Avijeet\|Anderson, Amy\|Giardina, Charles
PMID:	24338023

70.
Journal:	Dis Markers. 2014;2014:798170.
Title:	Expression of the microtubule-associated protein MAP9/ASAP and its partners AURKA and PLK1 in colorectal and breast cancers.
Author:	Rouquier, Sylvie\|Pillaire, Marie-Jeanne\|Cazaux, Christophe\|Giorgi, Dominique
PMID:	24876664

71.
Journal:	Nat Cell Biol. 2014 Aug;16(8):779-91.
Title:	Increased microtubule assembly rates influence chromosomal instability in colorectal cancer cells.
Author:	Ertych, Norman\|Stolz, Ailine\|Stenzinger, Albrecht\|Weichert, Wilko\|Kaulfuss, Silke\|Burfeind, Peter\|Aigner, Achim\|Wordeman, Linda\|Bastians, Holger
PMID:	24976383

72.
Journal:	BMC Complement Altern Med. 2014 Jul 24;14:264.
Title:	Cytotoxicity of Eupatorium cannabinum L. ethanolic extract against colon cancer cells and interactions with Bisphenol A and Doxorubicin.
Author:	Ribeiro-Varandas, Edna\|Ressurreicao, Filipe\|Viegas, Wanda\|Delgado, Margarida
PMID:	25056133

73.
Journal:	Nat Cell Biol. 2014 Aug;16(8):739-41.
Title:	A growing role for Aurora A in chromosome instability.
Author:	Maia, Ana R R\|van Heesbeen, Roy G H P\|Medema, Rene H
PMID:	25082197

74.
Journal:	J BUON. 2014 Jul-Sep;19(3):686-91.
Title:	Prognostic role of Aurora-A expression in metastatic colorectal cancer patients.
Author:	Goktas, Sevil\|Yildirim, Mustafa\|Suren, Dinc\|Alikanoglu, Arsenal Sezgin\|Dilli, Utku Donem\|Bulbuller, Nurullan\|Sezer, Cem\|Yildiz, Mustafa
PMID:	25261653

75.
Journal:	Exp Ther Med. 2015 Jan;9(1):219-226.
Title:	Serine/threonine kinase 15 gene polymorphism and risk of digestive system cancers: A meta-analysis.
Author:	Luo, Jianfei\|Yan, Ruicheng\|Zou, Li
PMID:	25452806

76.
Journal:	Hum Pathol. 2015 Mar;46(3):411-8.
Title:	Aurora kinase A gene copy number is associated with the malignant transformation of colorectal adenomas but not with the serrated neoplasia progression.
Author:	Casorzo, Laura\|Dell'Aglio, Carmine\|Sarotto, Ivana\|Risio, Mauro
PMID:	25596657

77.
Journal:	Ann Oncol. 2015 May;26(5):935-42.
Title:	The AURKA/TPX2 axis drives colon tumorigenesis cooperatively with MYC.
Author:	Takahashi, Y\|Sheridan, P\|Niida, A\|Sawada, G\|Uchi, R\|Mizuno, H\|Kurashige, J\|Sugimachi, K\|Sasaki, S\|Shimada, Y\|Hase, K\|Kusunoki, M\|Kudo, S\|Watanabe, M\|Yamada, K\|Sugihara, K\|Yamamoto, H\|Suzuki, A\|Doki, Y\|Miyano, S\|Mori, M\|Mimori, K
PMID:	25632068

78.
Journal:	Mol Cancer Ther. 2015 Jul;14(7):1693-704.
Title:	Daurinol Enhances the Efficacy of Radiotherapy in Lung Cancer via Suppression of Aurora Kinase A/B Expression.
Author:	Woo, Jong Kyu\|Kang, Ju-Hee\|Shin, DongYun\|Park, Seong-Hyeok\|Kang, Kyungsu\|Nho, Chu Won\|Seong, Je Kyung\|Lee, Sang-Jin\|Oh, Seung Hyun
PMID:	25882311

79.
Journal:	Biochem Biophys Res Commun. 2015 Jun 12;461(4):605-11.
Title:	Effects of KRC-108 on the Aurora A activity and growth of colorectal cancer cells.
Author:	Chung, Hye Jin\|Park, Kyeong Ryang\|Lee, Hyo Jeong\|Lee, Jongkook\|Kim, Jeong-Hyun\|Kim, Yong-Chul\|Han, Sun-Young
PMID:	25912878

80.
Journal:	Chem Biol Drug Des. 2015 Dec;86(6):1528-40.
Title:	Characterization of a Pyrazolo[4,3-d]pyrimidine Inhibitor of Cyclin-Dependent Kinases 2 and 5 and Aurora A With Pro-Apoptotic and Anti-Angiogenic Activity In Vitro.
Author:	Reznickova, Eva\|Weitensteiner, Sabine\|Havlicek, Libor\|Jorda, Radek\|Gucky, Tomas\|Berka, Karel\|Bazgier, Vaclav\|Zahler, Stefan\|Krystof, Vladimir\|Strnad, Miroslav
PMID:	26198005

81.
Journal:	Oncol Rep. 2015 Oct;34(4):1905-14.
Title:	Never in mitosis gene A-related kinase 6 and aurora kinase A: New gene biomarkers in the conversion from ulcerative colitis to colorectal cancer.
Author:	Gerceker, Emre\|Boyacioglu, Seda Orenay\|Kasap, Elmas\|Baykan, Ahmed\|Yuceyar, Hakan\|Yildirim, Hatice\|Ayhan, Semin\|Ellidokuz, Ender\|Korkmaz, Mehmet
PMID:	26259750

82.
Journal:	Toxicol In Vitro. 2015 Dec;29(8):2009-14.
Title:	Bisphenol A at the reference level counteracts doxorubicin transcriptional effects on cancer related genes in HT29 cells.
Author:	Delgado, Margarida\|Ribeiro-Varandas, Edna
PMID:	26320837

83.
Journal:	Yao Xue Xue Bao. 2015 Jul;50(7):854-60.
Title:	[The anti-tumor activity and molecular mechanisms of an Aurora kinase inhibitor ZLJ213 in suppressing colon cancer growth].
Author:	Zhou, Wan-qi\|Zhang, Li-jing\|Yang, Han-ze\|Feng, Zhi-qiang\|Li, Yan
PMID:	26552147

84.
Journal:	Int J Mol Sci. 2015 Dec 29;17(1). pii: ijms17010041.
Title:	Alisertib Induces Cell Cycle Arrest, Apoptosis, Autophagy and Suppresses EMT in HT29 and Caco-2 Cells.
Author:	Ren, Bao-Jun\|Zhou, Zhi-Wei\|Zhu, Da-Jian\|Ju, Yong-Le\|Wu, Jin-Hao\|Ouyang, Man-Zhao\|Chen, Xiao-Wu\|Zhou, Shu-Feng
PMID:	26729093

85.
Journal:	Tumour Biol. 2016 Mar;37(3):3071-80.
Title:	The potential role of the NEK6, AURKA, AURKB, and PAK1 genes in adenomatous colorectal polyps and colorectal adenocarcinoma.
Author:	Kasap, Elmas\|Gerceker, Emre\|Boyacioglu, Seda Orenay\|Yuceyar, Hakan\|Yildirm, Hatice\|Ayhan, Semin\|Korkmaz, Mehmet
PMID:	26423403

86.
Journal:	Nucl Med Biol. 2016 Jan;43(1):63-72.
Title:	Molecular imaging of aurora kinase A (AURKA) expression: Synthesis and preclinical evaluation of radiolabeled alisertib (MLN8237).
Author:	Goos, Jeroen A C M\|Verbeek, Joost\|Geldof, Albert A\|Hiemstra, Annemieke C\|van de Wiel, Mark A\|Adamzek, Kevin A\|Delis-Van Diemen, Pien M\|Stroud, Stephen G\|Bradley, Daniel P\|Meijer, Gerrit A\|Hoekstra, Otto S\|Fijneman, Remond J A\|Windhorst, Albert D
PMID:	26432753

87.
Journal:	Oncotarget. 2016 Jan 12;7(2):2123-34.
Title:	A prognostic classifier for patients with colorectal cancer liver metastasis, based on AURKA, PTGS2 and MMP9.
Author:	Goos, Jeroen A C M\|Coupe, Veerle M H\|van de Wiel, Mark A\|Diosdado, Begona\|Delis-Van Diemen, Pien M\|Hiemstra, Annemieke C\|de Cuba, Erienne M V\|Belien, Jeroen A M\|Menke-van der Houven van Oordt, C Willemien\|Geldof, Albert A\|Meijer, Gerrit A\|Hoekstra, Otto S
PMID:	26497206

88.
Journal:	Int J Oncol. 2016 Aug;49(2):603-10.
Title:	Tanshinone I induces human colorectal cancer cell apoptosis: The potential roles of Aurora A-p53 and survivin-mediated signaling pathways.
Author:	Lu, Mingjie\|Wang, Chen\|Wang, Jian
PMID:	27279458

89.
Journal:	Oncotarget. 2016 Jul 19;7(29):45803-45818.
Title:	Over-expression of AURKA, SKA3 and DSN1 contributes to colorectal adenoma to carcinoma progression.
Author:	Chuang, Tzu-Po\|Wang, Jaw-Yuan\|Jao, Shu-Wen\|Wu, Chang-Chieh\|Chen, Jiann-Hwa\|Hsiao, Koung-Hung\|Lin, Chung-Yen\|Chen, Shu-Hwa\|Su, Sheng-Yao\|Chen, Ying-Ju\|Chen, Yuan-Tsong\|Wu, Deng-Chyang\|Li, Ling-Hui
PMID:	27329586

90.
Journal:	Oncotarget. 2016 Aug 2;7(31):50290-50301.
Title:	Antitumor activity of the aurora a selective kinase inhibitor, alisertib, against preclinical models of colorectal cancer.
Author:	Pitts, Todd M\|Bradshaw-Pierce, Erica L\|Bagby, Stacey M\|Hyatt, Stephanie L\|Selby, Heather M\|Spreafico, Anna\|Tentler, John J\|McPhillips, Kelly\|Klauck, Peter J\|Capasso, Anna\|Diamond, Jennifer R\|Davis, S Lindsey\|Tan, Aik Choon\|Arcaroli, John J\|Purkey, Alicia\|
PMID:	27385211

91.
Journal:	Biomed Pharmacother. 2016 Aug;82:413-24.
Title:	Targeting the interaction of Aurora kinases and SIRT1 mediated by Wnt signaling pathway in colorectal cancer: A critical review.
Author:	Subramaniyan, Boopathi\|Jagadeesan, Kaviya\|Ramakrishnan, Sabitha\|Mathan, Ganeshan
PMID:	27470380

92.
Journal:	Oncotarget. 2016 Nov 22;7(47):76852-76866.
Title:	Epigenetic silencing of miR-137 contributes to early colorectal carcinogenesis by impaired Aurora-A inhibition.
Author:	Huang, Yu-Chuan\|Lee, Chung-Ta\|Lee, Jenq-Chang\|Liu, Yao-Wen\|Chen, Ying-Jen\|Tseng, Joseph T\|Kang, Jui-Wen\|Sheu, Bor-Shyang\|Lin, Bo-Wen\|Hung, Liang-Yi
PMID:	27764771

93.
Journal:	Mol Med Rep. 2017 Feb;15(2):867-872.
Title:	Identification of key genes in colorectal cancer using random walk with restart.
Author:	Cui, Xiaofeng\|Shen, Kexin\|Xie, Zhongshi\|Liu, Tongjun\|Zhang, Haishan
PMID:	28000901

94.
Journal:	Int J Cancer. 2017 Apr 1;140(7):1653-1661.
Title:	Copy number variations in DCC/18q and ERBB2/17q are associated with disease-free survival in microsatellite stable colon cancer.
Author:	Sefrioui, David\|Vermeulin, Thomas\|Blanchard, France\|Chapusot, Caroline\|Beaussire, Ludivine\|Armengol-Debeir, Laura\|Sesboue, Richard\|Gangloff, Alice\|Hebbar, Mohamed\|Copin, Marie-Christine\|Houivet, Estelle\|Schwarz, Lilian\|Clatot, Florian\|Tuech, Jean-Jacques\|
PMID:	28006840

95.
Journal:	J Pathol Transl Med. 2017 Jan;51(1):32-39.
Title:	Aurora Kinase A Is a Prognostic Marker in Colorectal Adenocarcinoma.
Author:	Koh, Hyun Min\|Jang, Bo Geun\|Hyun, Chang Lim\|Kim, Young Sill\|Hyun, Jin Won\|Chang, Weon Young\|Maeng, Young Hee
PMID:	28013532

96.
Journal:	Cell Death Dis. 2017 Jan 12;8(1):e2555.
Title:	Translational upregulation of Aurora-A by hnRNP Q1 contributes to cell proliferation and tumorigenesis in colorectal cancer.
Author:	Lai, Chien-Hsien\|Huang, Yu-Chuan\|Lee, Jenq-Chang\|Tseng, Joseph Ta-Chien\|Chang, Kung-Chao\|Chen, Yen-Ju\|Ding, Nai-Jhu\|Huang, Pao-Hsuan\|Chang, Wen-Chang\|Lin, Bo-Wen\|Chen, Ruo-Yu\|Wang, Yu-Chu\|Lai, Yi-Chien\|Hung, Liang-Yi
PMID:	28079881

97.
Journal:	Oncotarget. 2017 Mar 14;8(11):18106-18117.
Title:	3'-hydroxy-4'-methoxy-beta-methyl-beta-nitrostyrene inhibits tumorigenesis in colorectal cancer cells through ROS-mediated DNA damage and mitochondrial dysfunction.
Author:	Tsai, Chun-Hao\|Hung, Amos C\|Chen, Yuan-Yin\|Chiu, Ya-Wen\|Hsieh, Pei-Wen\|Lee, Yi-Chen\|Su, Yu-Han\|Chang, Po-Chih\|Hu, Stephen Chu-Sung\|Yuan, Shyng-Shiou F
PMID:	28178649

98.
Journal:	Immune Netw. 2017 Apr;17(2):110-115.
Title:	Characterization of the Indirubin Derivative LDD970 as a Small Molecule Aurora Kinase A Inhibitor in Human Colorectal Cancer Cells.
Author:	Ndolo, Karyn Muzinga\|Park, Kyeong Ryang\|Lee, Hyo Jeong\|Yoon, Kyoung Bin\|Kim, Yong-Chul\|Han, Sun-Young
PMID:	28458622

99.
Journal:	Oncol Lett. 2017 Dec;14(6):6571-6577.
Title:	Aurora kinase A inhibitor TCS7010 demonstrates pro-apoptotic effect through the unfolded protein response pathway in HCT116 colon cancer cells.
Author:	Lee, Da Hyun\|Kim, Chang Gun\|Lim, Yoongho\|Shin, Soon Young
PMID:	29163689

100.
Journal:	Eur J Med Chem. 2018 May 10;151:533-545.
Title:	Design and synthesis of BPR1K653 derivatives targeting the back pocket of Aurora kinases for selective isoform inhibition.
Author:	Ke, Yi-Yu\|Chang, Chun-Ping\|Lin, Wen-Hsing\|Tsai, Chia-Hua\|Chiu, I-Chen\|Wang, Wan-Ping\|Wang, Pei-Chen\|Chen, Pei-Yi\|Lin, Wen-Hsin\|Chang, Chun-Feng\|Kuo, Po-Chu\|Song, Jen-Shin\|Shih, Chuan\|Hsieh, Hsing-Pang\|Chi, Ya-Hui
PMID:	29656197

101.
Journal:	Sci Rep. 2018 May 14;8(1):7522.
Title:	Aurora kinase A (AURKA) interaction with Wnt and Ras-MAPK signalling pathways in colorectal cancer.
Author:	Jacobsen, Annika\|Bosch, Linda J W\|Martens-de Kemp, Sanne R\|Carvalho, Beatriz\|Sillars-Hardebol, Anke H\|Dobson, Richard J\|de Rinaldis, Emanuele\|Meijer, Gerrit A\|Abeln, Sanne\|Heringa, Jaap\|Fijneman, Remond J A\|Feenstra, K Anton
PMID:	29760449

102.
Journal:	Mol Cancer Res. 2018 Sep;16(9):1361-1372.
Title:	Spindle Assembly Disruption and Cancer Cell Apoptosis with a CLTC-Binding Compound.
Author:	Bond, Michael J\|Bleiler, Marina\|Harrison, Lauren E\|Scocchera, Eric W\|Nakanishi, Masako\|G-Dayanan, Narendran\|Keshipeddy, Santosh\|Rosenberg, Daniel W\|Wright, Dennis L\|Giardina, Charles
PMID:	29769406

103.
Journal:	Nat Commun. 2018 Aug 10;9(1):3212.
Title:	Targeting AURKA-CDC25C axis to induce synthetic lethality in ARID1A-deficient colorectal cancer cells.
Author:	Wu, Changjie\|Lyu, Junfang\|Yang, Eun Ju\|Liu, Yifan\|Zhang, Baoyuan\|Shim, Joong Sup
PMID:	30097580

104.
Journal:	Cancer Lett. 2018 Nov 1;436:28-37.
Title:	PTEN deficiency confers colorectal cancer cell resistance to dual inhibitors of FLT3 and aurora kinase A.
Author:	Liu, Yifan\|Yang, Eun Ju\|Zhang, Baoyuan\|Miao, Zhengqiang\|Wu, Changjie\|Lyu, Junfang\|Tan, Kaeling\|Poon, Terence Chuen Wai\|Shim, Joong Sup
PMID:	30118842

105.
Journal:	Invest New Drugs. 2018 Sep 6. pii: 10.1007/s10637-018-0663-0.
Title:	Phase I study combining the aurora kinase a inhibitor alisertib with mFOLFOX in gastrointestinal cancer.
Author:	Goff, Laura W\|Azad, Nilo\|Stein, Stacey\|Whisenant, Jennifer G\|Koyama, Tatsuki\|Vaishampayan, Ulka\|Hochster, Howard\|Connolly, Roisin\|Weise, Amy\|LoRusso, Patricia M\|Salaria, Safia N\|El-Rifai, Wael\|Berlin, Jordan D
PMID:	30191522

106.
Journal:	Gastroenterology. 2018 Oct 17. pii: S0016-5085(18)35161-8.
Title:	Inhibition of AURKA Reduces Proliferation and Survival of Gastrointestinal Cancer Cells With Activated KRAS by Preventing Activation of RPS6KB1.
Author:	Wang-Bishop, Lihong\|Chen, Zheng\|Gomaa, Ahmed\|Lockhart, Albert Craig\|Salaria, Safia\|Wang, Jialiang\|Lewis, Keeli B\|Ecsedy, Jeffrey\|Washington, Kay\|Beauchamp, Robert Daniel\|El-Rifai, Wael
PMID:	30342037