Primary Site >> Pancreatic Cancer
Gene >> ATR
| 1. | |||||||||||
| Journal: | Clin Cancer Res. 2008 Apr 1;14(7):2042-8. | ||||||||||
| Title: | Single-nucleotide polymorphisms of DNA damage response genes are associated with overall survival in patients with pancreatic cancer. | ||||||||||
| Author: | Okazaki, Taro|Jiao, Li|Chang, Ping|Evans, Douglas B|Abbruzzese, James L|Li, Donghui | ||||||||||
| PMID: | 18381943 | ||||||||||
| 2. | |||||||||||
| Journal: | Cancer Res. 2010 Jun 15;70(12):4972-81. | ||||||||||
| Title: | Mechanism of radiosensitization by the Chk1/2 inhibitor AZD7762 involves abrogation of the G2 checkpoint and inhibition of homologous recombinational DNA repair. | ||||||||||
| Author: | Morgan, Meredith A|Parsels, Leslie A|Zhao, Lili|Parsels, Joshua D|Davis, Mary A|Hassan, Maria C|Arumugarajah, Sankari|Hylander-Gans, Linda|Morosini, Deborah|Simeone, Diane M|Canman, Christine E|Normolle, Daniel P|Zabludoff, Sonya D|Maybaum, Jonathan|Lawre | ||||||||||
| PMID: | 20501833 | ||||||||||
| 3. | |||||||||||
| Journal: | Nat Struct Mol Biol. 2011 Nov 27;18(12):1331-5. | ||||||||||
| Title: | Exploiting oncogene-induced replicative stress for the selective killing of Myc-driven tumors. | ||||||||||
| Author: | Murga, Matilde|Campaner, Stefano|Lopez-Contreras, Andres J|Toledo, Luis I|Soria, Rebeca|Montana, Maria F|D'Artista, Luana|Schleker, Thomas|Guerra, Carmen|Garcia, Elena|Barbacid, Mariano|Hidalgo, Manuel|Amati, Bruno|Fernandez-Capetillo, Oscar | ||||||||||
| PMID: | 22120667 | ||||||||||
| 4. | |||||||||||
| Journal: | Cancer Biol Ther. 2012 Sep;13(11):1072-81. | ||||||||||
| Title: | The novel ATR inhibitor VE-821 increases sensitivity of pancreatic cancer cells to radiation and chemotherapy. | ||||||||||
| Author: | Prevo, Remko|Fokas, Emmanouil|Reaper, Philip M|Charlton, Peter A|Pollard, John R|McKenna, W Gillies|Muschel, Ruth J|Brunner, Thomas B | ||||||||||
| PMID: | 22825331 | ||||||||||
| 5. | |||||||||||
| Journal: | Cell Death Dis. 2012 Dec 6;3:e441. | ||||||||||
| Title: | Targeting ATR in vivo using the novel inhibitor VE-822 results in selective sensitization of pancreatic tumors to radiation. | ||||||||||
| Author: | Fokas, E|Prevo, R|Pollard, J R|Reaper, P M|Charlton, P A|Cornelissen, B|Vallis, K A|Hammond, E M|Olcina, M M|Gillies McKenna, W|Muschel, R J|Brunner, T B | ||||||||||
| PMID: | 23222511 | ||||||||||
| 6. | |||||||||||
| Journal: | Oncotarget. 2015 May 30;6(15):13072-87. | ||||||||||
| Title: | Wee1 is required to sustain ATR/Chk1 signaling upon replicative stress. | ||||||||||
| Author: | Saini, Priyanka|Li, Yizhu|Dobbelstein, Matthias | ||||||||||
| PMID: | 25965828 | ||||||||||
| 7. | |||||||||||
| Journal: | Cell Rep. 2016 Jun 28;16(1):133-147. | ||||||||||
| Title: | In Vivo Functional Platform Targeting Patient-Derived Xenografts Identifies WDR5-Myc Association as a Critical Determinant of Pancreatic Cancer. | ||||||||||
| Author: | Carugo, Alessandro|Genovese, Giannicola|Seth, Sahil|Nezi, Luigi|Rose, Johnathon Lynn|Bossi, Daniela|Cicalese, Angelo|Shah, Parantu Krushnakant|Viale, Andrea|Pettazzoni, Piergiorgio Francesco|Akdemir, Kadir Caner|Bristow, Christopher Aaron|Robinson, Freder | ||||||||||
| PMID: | 27320920 | ||||||||||
| 8. | |||||||||||
| Journal: | J Biol Chem. 2016 Oct 14;291(42):21956-21962. | ||||||||||
| Title: | Ewing Tumor-associated Antigen 1 Interacts with Replication Protein A to Promote Restart of Stalled Replication Forks. | ||||||||||
| Author: | Feng, Sumin|Zhao, Yichao|Xu, Yixi|Ning, Shaokai|Huo, Wei|Hou, Mei|Gao, Ge|Ji, Jianguo|Guo, Rong|Xu, Dongyi | ||||||||||
| PMID: | 27601467 | ||||||||||
| 9. | |||||||||||
| Journal: | World J Gastroenterol. 2016 Aug 28;22(32):7275-88. | ||||||||||
| Title: | Perspectives on the combination of radiotherapy and targeted therapy with DNA repair inhibitors in the treatment of pancreatic cancer. | ||||||||||
| Author: | Yang, Shih-Hung|Kuo, Ting-Chun|Wu, Hsu|Guo, Jhe-Cyuan|Hsu, Chiun|Hsu, Chih-Hung|Tien, Yu-Wen|Yeh, Kun-Huei|Cheng, Ann-Lii|Kuo, Sung-Hsin | ||||||||||
| PMID: | 27621574 | ||||||||||
| 10. | |||||||||||
| Journal: | Oncol Rep. 2017 Jun;37(6):3377-3386. | ||||||||||
| Title: | Inhibition of ATR potentiates the cytotoxic effect of gemcitabine on pancreatic cancer cells through enhancement of DNA damage and abrogation of ribonucleotide reductase induction by gemcitabine. | ||||||||||
| Author: | Liu, Shuang|Ge, Yubin|Wang, Tingting|Edwards, Holly|Ren, Qihang|Jiang, Yiqun|Quan, Chengshi|Wang, Guan | ||||||||||
| PMID: | 28440428 | ||||||||||
| 11. | |||||||||||
| Journal: | PLoS One. 2017 May 30;12(5):e0178221. | ||||||||||
| Title: | The G2 checkpoint inhibitor CBP-93872 increases the sensitivity of colorectal and pancreatic cancer cells to chemotherapy. | ||||||||||
| Author: | Iwata, Tsutomu|Uchino, Tairin|Koyama, Ayako|Johmura, Yoshikazu|Koyama, Kenichi|Saito, Takuya|Ishiguro, Seiji|Arikawa, Takashi|Komatsu, Shunichiro|Miyachi, Masahiko|Sano, Tsuyoshi|Nakanishi, Makoto|Shimada, Midori | ||||||||||
| PMID: | 28558031 | ||||||||||
| 12. | |||||||||||
| Journal: | Int J Mol Sci. 2017 Aug 31;18(9). pii: ijms18091886. | ||||||||||
| Title: | The Role of PALB2 in the DNA Damage Response and Cancer Predisposition. | ||||||||||
| Author: | Nepomuceno, Thales C|De Gregoriis, Giuliana|de Oliveira, Francisco M Bastos|Suarez-Kurtz, Guilherme|Monteiro, Alvaro N|Carvalho, Marcelo A | ||||||||||
| PMID: | 28858227 | ||||||||||
| 13. | |||||||||||
| Journal: | Biomed Pharmacother. 2018 Jan;97:1250-1258. | ||||||||||
| Title: | Vildagliptin loaded triangular DNA nanospheres coated with eudragit for oral delivery and better glycemic control in type 2 diabetes mellitus. | ||||||||||
| Author: | Baig, Mirza Muhammad Faran Ashraf|Khan, Sara|Naeem, Muhammad Ahsan|Khan, Ghulam Jilany|Ansari, Muhammad Tayyab | ||||||||||
| PMID: | 29145151 | ||||||||||
| 14. | |||||||||||
| Journal: | Oncol Lett. 2018 Jun;15(6):8878-8884. | ||||||||||
| Title: | 3F-Box protein 32 degrades ataxia telangiectasia and Rad3-related and regulates DNA damage response induced by gemcitabine in pancreatic cancer. | ||||||||||
| Author: | Yang, Chong|Fan, Ping|Zhu, Shikai|Yang, Hongji|Jin, Xin|Wu, Heshui | ||||||||||
| PMID: | 29805624 | ||||||||||