Literatures

Primary Site >> Pancreatic Cancer

Gene >> ATM

1.
Journal:	Breast Cancer Res. 2004;6(4):R366-71. Epub 2004 May 14.
Title:	No germline mutations in the histone acetyltransferase gene EP300 in BRCA1 and BRCA2 negative families with breast cancer and gastric, pancreatic, or colorectal cancer.
Author:	Campbell, Ian G\|Choong, David\|Chenevix-Trench, Georgia
PMID:	15217503

2.
Journal:	Biochem Biophys Res Commun. 2004 Nov 19;324(3):986-92.
Title:	IGF-1 phosphorylates AMPK-alpha subunit in ATM-dependent and LKB1-independent manner.
Author:	Suzuki, Atsushi\|Kusakai, Gen-ichi\|Kishimoto, Atsuhiro\|Shimojo, Yosuke\|Ogura, Tsutomu\|Lavin, Martin F\|Esumi, Hiroyasu
PMID:	15485651

3.
Journal:	Fam Cancer. 2004;3(3-4):233-40.
Title:	Familial pancreatic carcinoma in Jews.
Author:	Lynch, Henry T\|Deters, Carolyn A\|Lynch, Jane F\|Brand, Randall E
PMID:	15516847

4.
Journal:	Pancreas. 2004 May;28(4):421-6.
Title:	Expression of ATM protein and its relationship with p53 in pancreatic carcinoma with tissue array.
Author:	Yu, Guanzhen\|Zhu, Ming-hua\|Zhu, Zhi\|Ni, Can-rong\|Zheng, Jian-ming\|Li, Fang-mei
PMID:	15097860

5.
Journal:	J Gastroenterol Hepatol. 2005 Jul;20(7):1046-53.
Title:	Neutral lipid isolated from endosperm of Job's tears inhibits the growth of pancreatic cancer cells via apoptosis, G2/M arrest, and regulation of gene expression.
Author:	Bao, Ying\|Yuan, Yaozong\|Xia, Lu\|Jiang, Hua\|Wu, Weirong\|Zhang, Xuejun
PMID:	15955213

6.
Journal:	Zhonghua Bing Li Xue Za Zhi. 2005 Jul;34(7):389-92.
Title:	[Mucinous noncystic (colloid) adenocarcinoma of the pancreas].
Author:	Zhu, Ming-hua\|Hu, Xian-gui\|Ni, Can-rong\|Zhang, Shun-min\|Xi, Peng-cheng\|Yu, Guan-zhen
PMID:	16251039

7.
Journal:	Ai Zheng. 2005 Nov;24(11):1398-403.
Title:	[Expression and clinical significance of P53 pathway-associated proteins in pancreatic carcinoma].
Author:	Yu, Guan-Zhen\|Zhu, Ming-Hua\|Chen, Ying\|Ni, Can-Rong\|Li, Fang-Mei
PMID:	16552971

8.
Journal:	J Clin Oncol. 2006 Apr 10;24(11):1720-8. Epub 2006 Mar 6.
Title:	Single nucleotide polymorphisms of RecQ1, RAD54L, and ATM genes are associated with reduced survival of pancreatic cancer.
Author:	Li, Donghui\|Frazier, Marsha\|Evans, Douglas B\|Hess, Kenneth R\|Crane, Christopher H\|Jiao, Li\|Abbruzzese, James L
PMID:	16520463

9.
Journal:	Cancer Biol Ther. 2007 Mar;6(3):367-76. Epub 2007 Mar 13.
Title:	Basic transcription factor 3 (BTF3) regulates transcription of tumor-associated genes in pancreatic cancer cells.
Author:	Kusumawidjaja, Grace\|Kayed, Hany\|Giese, Nathalia\|Bauer, Andrea\|Erkan, Mert\|Giese, Thomas\|Hoheise, Jorg D\|Friess, Helmut\|Kleeff, Jorg
PMID:	17312387

10.
Journal:	J Clin Invest. 2007 May;117(5):1440-9. Epub 2007 Apr 12.
Title:	Fanconi anemia pathway-deficient tumor cells are hypersensitive to inhibition of ataxia telangiectasia mutated.
Author:	Kennedy, Richard D\|Chen, Clark C\|Stuckert, Patricia\|Archila, Elyse M\|De la Vega, Michelle A\|Moreau, Lisa A\|Shimamura, Akiko\|D'Andrea, Alan D
PMID:	17431503

11.
Journal:	Cancer Res. 2007 Jul 15;67(14):6936-45.
Title:	Nonhomologous end joining is essential for cellular resistance to the novel antitumor agent, beta-lapachone.
Author:	Bentle, Melissa S\|Reinicke, Kathryn E\|Dong, Ying\|Bey, Erik A\|Boothman, David A
PMID:	17638905

12.
Journal:	Clin Cancer Res. 2008 Apr 1;14(7):2042-8.
Title:	Single-nucleotide polymorphisms of DNA damage response genes are associated with overall survival in patients with pancreatic cancer.
Author:	Okazaki, Taro\|Jiao, Li\|Chang, Ping\|Evans, Douglas B\|Abbruzzese, James L\|Li, Donghui
PMID:	18381943

13.
Journal:	Clin Cancer Res. 2009 Jan 15;15(2):740-6.
Title:	DNA repair gene polymorphisms and risk of pancreatic cancer.
Author:	Li, Donghui\|Suzuki, Hideo\|Liu, Bingrong\|Morris, Jeffrey\|Liu, Jun\|Okazaki, Taro\|Li, Yanan\|Chang, Ping\|Abbruzzese, James L
PMID:	19147782

14.
Journal:	Br J Cancer. 2009 May 5;100(9):1425-33.
Title:	Activation of ATM/Chk1 by curcumin causes cell cycle arrest and apoptosis in human pancreatic cancer cells.
Author:	Sahu, R P\|Batra, S\|Srivastava, S K
PMID:	19401701

15.
Journal:	Cancer Res. 2010 Jun 15;70(12):4972-81.
Title:	Mechanism of radiosensitization by the Chk1/2 inhibitor AZD7762 involves abrogation of the G2 checkpoint and inhibition of homologous recombinational DNA repair.
Author:	Morgan, Meredith A\|Parsels, Leslie A\|Zhao, Lili\|Parsels, Joshua D\|Davis, Mary A\|Hassan, Maria C\|Arumugarajah, Sankari\|Hylander-Gans, Linda\|Morosini, Deborah\|Simeone, Diane M\|Canman, Christine E\|Normolle, Daniel P\|Zabludoff, Sonya D\|Maybaum, Jonathan\|Lawre
PMID:	20501833

16.
Journal:	PLoS One. 2010 Sep 8;5(9):e12653.
Title:	Mutational profiling of kinases in human tumours of pancreatic origin identifies candidate cancer genes in ductal and ampulla of vater carcinomas.
Author:	Corbo, Vincenzo\|Ritelli, Rossana\|Barbi, Stefano\|Funel, Niccola\|Campani, Daniela\|Bardelli, Alberto\|Scarpa, Aldo
PMID:	20838624

17.
Journal:	Invest New Drugs. 2011 Oct;29(5):1057-65.
Title:	Thymidylate synthase (TYMS) enhancer region genotype-directed phase II trial of oral capecitabine for 2nd line treatment of advanced pancreatic cancer.
Author:	Weekes, Colin D\|Nallapareddy, Sujatha\|Rudek, Michelle A\|Norris-Kirby, Alexis\|Laheru, Daniel\|Jimeno, Antonio\|Donehower, Ross C\|Murphy, Kathleen M\|Hidalgo, Manuel\|Baker, Sharyn D\|Messersmith, Wells A
PMID:	20306339

18.
Journal:	Mol Biol Rep. 2012 May;39(5):5719-25.
Title:	Association between ATM polymorphisms and cancer risk: a meta-analysis.
Author:	Shen, Li\|Yin, Zhi-Hua\|Wan, Yan\|Zhang, Yue\|Li, Kun\|Zhou, Bao-Sen
PMID:	22203481

19.
Journal:	Cell Death Dis. 2012 Dec 6;3:e441.
Title:	Targeting ATR in vivo using the novel inhibitor VE-822 results in selective sensitization of pancreatic tumors to radiation.
Author:	Fokas, E\|Prevo, R\|Pollard, J R\|Reaper, P M\|Charlton, P A\|Cornelissen, B\|Vallis, K A\|Hammond, E M\|Olcina, M M\|Gillies McKenna, W\|Muschel, R J\|Brunner, T B
PMID:	23222511

20.
Journal:	Cancer J. 2012 Nov-Dec;18(6):485-91.
Title:	Inherited pancreatic cancer syndromes.
Author:	Solomon, Sheila\|Das, Siddhartha\|Brand, Randall\|Whitcomb, David C
PMID:	23187834

21.
Journal:	Nature. 2012 Nov 15;491(7424):399-405.
Title:	Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes.
Author:	Biankin, Andrew V\|Waddell, Nicola\|Kassahn, Karin S\|Gingras, Marie-Claude\|Muthuswamy, Lakshmi B\|Johns, Amber L\|Miller, David K\|Wilson, Peter J\|Patch, Ann-Marie\|Wu, Jianmin\|Chang, David K\|Cowley, Mark J\|Gardiner, Brooke B\|Song, Sarah\|Harliwong, Ivon\|Idrisog
PMID:	23103869

22.
Journal:	Nat Rev Gastroenterol Hepatol. 2012 Aug;9(8):445-53.
Title:	Familial pancreatic cancer--current knowledge.
Author:	Bartsch, Detlef K\|Gress, Thomas M\|Langer, Peter
PMID:	22664588

23.
Journal:	Cancer Discov. 2012 Jan;2(1):41-6.
Title:	ATM mutations in patients with hereditary pancreatic cancer.
Author:	Roberts, Nicholas J\|Jiao, Yuchen\|Yu, Jun\|Kopelovich, Levy\|Petersen, Gloria M\|Bondy, Melissa L\|Gallinger, Steven\|Schwartz, Ann G\|Syngal, Sapna\|Cote, Michele L\|Axilbund, Jennifer\|Schulick, Richard\|Ali, Syed Z\|Eshleman, James R\|Velculescu, Victor E\|Goggins,
PMID:	22585167

24.
Journal:	Cancer Discov. 2012 Jan;2(1):14-5.
Title:	A role for ATM in hereditary pancreatic cancer.
Author:	Bakker, Janine L\|de Winter, Johan P
PMID:	22585162

25.
Journal:	ACS Chem Biol. 2012 Jul 20;7(7):1152-7.
Title:	A small-molecule probe of the histone methyltransferase G9a induces cellular senescence in pancreatic adenocarcinoma.
Author:	Yuan, Yuan\|Wang, Qiu\|Paulk, Joshiawa\|Kubicek, Stefan\|Kemp, Melissa M\|Adams, Drew J\|Shamji, Alykhan F\|Wagner, Bridget K\|Schreiber, Stuart L
PMID:	22536950

26.
Journal:	J Cell Physiol. 2012 Jun;227(6):2586-94.
Title:	Mechanism of T-oligo-induced cell cycle arrest in Mia-PaCa pancreatic cancer cells.
Author:	Rankin, Andrew M\|Sarkar, Sibaji\|Faller, Douglas V
PMID:	21898405

27.
Journal:	Invest New Drugs. 2013 Oct;31(5):1115-24.
Title:	Digalloylresveratrol, a novel resveratrol analog inhibits the growth of human pancreatic cancer cells.
Author:	Saiko, Philipp\|Graser, Geraldine\|Giessrigl, Benedikt\|Steinmann, Marie-Therese\|Schuster, Heike\|Lackner, Andreas\|Grusch, Michael\|Krupitza, Georg\|Jaeger, Walter\|Somepalli, Venkateswarlu\|Golakoti, Trimurtulu\|Fritzer-Szekeres, Monika\|Szekeres, Thomas
PMID:	23943154

28.
Journal:	Pathol Res Pract. 2013 Oct;209(10):635-9.
Title:	Influence of MRE11, RAD50 and NIBRIN protein expression on survival in pancreatic carcinoma after curative resection.
Author:	Horst, Klemens\|Ganzera, Silke\|Kaisers, Wolfgang\|Munding, Johanna\|Flott-Rahmel, Berenike\|Tannapfel, Andrea\|Zirngibl, Hubert
PMID:	23954013

29.
Journal:	J Pathol. 2014 Mar;232(4):428-35.
Title:	Whole-exome sequencing of pancreatic neoplasms with acinar differentiation.
Author:	Jiao, Yuchen\|Yonescu, Raluca\|Offerhaus, G Johan A\|Klimstra, David S\|Maitra, Anirban\|Eshleman, James R\|Herman, James G\|Poh, Weijie\|Pelosof, Lorraine\|Wolfgang, Christopher L\|Vogelstein, Bert\|Kinzler, Kenneth W\|Hruban, Ralph H\|Papadopoulos, Nickolas\|Wood, La
PMID:	24293293

30.
Journal:	Genes Dev. 2014 Jan 1;28(1):1-7.
Title:	Familial pancreatic cancer: genetic advances.
Author:	Rustgi, Anil K
PMID:	24395243

31.
Journal:	Cancer Res. 2014 Mar 15;74(6):1778-88.
Title:	ATDC/TRIM29 phosphorylation by ATM/MAPKAP kinase 2 mediates radioresistance in pancreatic cancer cells.
Author:	Wang, Lidong\|Yang, Huibin\|Palmbos, Phillip L\|Ney, Gina\|Detzler, Taylor Ann\|Coleman, Dawn\|Leflein, Jacob\|Davis, Mary\|Zhang, Min\|Tang, Wenhua\|Hicks, J Kevin\|Helchowski, Corey M\|Prasad, Jayendra\|Lawrence, Theodore S\|Xu, Liang\|Yu, Xiaochun\|Canman, Christine E
PMID:	24469230

32.
Journal:	Clin Cancer Res. 2014 Apr 1;20(7):1865-72.
Title:	Having pancreatic cancer with tumoral loss of ATM and normal TP53 protein expression is associated with a poorer prognosis.
Author:	Kim, Haeryoung\|Saka, Burcu\|Knight, Spencer\|Borges, Michael\|Childs, Erica\|Klein, Alison\|Wolfgang, Christopher\|Herman, Joseph\|Adsay, Volkan N\|Hruban, Ralph H\|Goggins, Michael
PMID:	24486587

33.
Journal:	Cell Death Dis. 2014 Apr 24;5:e1199.
Title:	APPL proteins modulate DNA repair and radiation survival of pancreatic carcinoma cells by regulating ATM.
Author:	Hennig, J\|McShane, M P\|Cordes, N\|Eke, I
PMID:	24763056

34.
Journal:	Nat Commun. 2015 Jul 29;6:7677.
Title:	Loss of ATM accelerates pancreatic cancer formation and epithelial-mesenchymal transition.
Author:	Russell, Ronan\|Perkhofer, Lukas\|Liebau, Stefan\|Lin, Qiong\|Lechel, Andre\|Feld, Fenja M\|Hessmann, Elisabeth\|Gaedcke, Jochen\|Guthle, Melanie\|Zenke, Martin\|Hartmann, Daniel\|von Figura, Guido\|Weissinger, Stephanie E\|Rudolph, Karl-Lenhard\|Moller, Peter\|Lennerz,
PMID:	26220524

35.
Journal:	Nat Genet. 2015 Aug;47(8):911-6.
Title:	Common variation at 2p13.3, 3q29, 7p13 and 17q25.1 associated with susceptibility to pancreatic cancer.
Author:	Childs, Erica J\|Mocci, Evelina\|Campa, Daniele\|Bracci, Paige M\|Gallinger, Steven\|Goggins, Michael\|Li, Donghui\|Neale, Rachel E\|Olson, Sara H\|Scelo, Ghislaine\|Amundadottir, Laufey T\|Bamlet, William R\|Bijlsma, Maarten F\|Blackford, Amanda\|Borges, Michael\|Brenn
PMID:	26098869

36.
Journal:	Mol Cancer Res. 2015 Aug;13(8):1174-84.
Title:	PTK6 Potentiates Gemcitabine-Induced Apoptosis by Prolonging S-phase and Enhancing DNA Damage in Pancreatic Cancer.
Author:	Ono, Hiroaki\|Basson, Marc D\|Ito, Hiromichi
PMID:	26013168

37.
Journal:	Clin Cancer Res. 2015 May 1;21(9):2029-37.
Title:	Precision Medicine for Advanced Pancreas Cancer: The Individualized Molecular Pancreatic Cancer Therapy (IMPaCT) Trial.
Author:	Chantrill, Lorraine A\|Nagrial, Adnan M\|Watson, Clare\|Johns, Amber L\|Martyn-Smith, Mona\|Simpson, Skye\|Mead, Scott\|Jones, Marc D\|Samra, Jaswinder S\|Gill, Anthony J\|Watson, Nicole\|Chin, Venessa T\|Humphris, Jeremy L\|Chou, Angela\|Brown, Belinda\|Morey, Adrienne
PMID:	25896973

38.
Journal:	Gastroenterology. 2015 Mar;148(3):556-64.
Title:	Prevalence of germline mutations in cancer predisposition genes in patients with pancreatic cancer.
Author:	Grant, Robert C\|Selander, Iris\|Connor, Ashton A\|Selvarajah, Shamini\|Borgida, Ayelet\|Briollais, Laurent\|Petersen, Gloria M\|Lerner-Ellis, Jordan\|Holter, Spring\|Gallinger, Steven
PMID:	25479140

39.
Journal:	Biomed Sci Instrum. 2015;51:393-9.
Title:	The Effects of Metformin and EGCG On PANC-1 Cell Survival.
Author:	Hodges, Victoria\|Tucci, Michelle\|Benghuzzi, Hamed
PMID:	25996744

40.
Journal:	Cancer Epidemiol Biomarkers Prev. 2016 Jul;25(7):1185-91.
Title:	Association of Common Susceptibility Variants of Pancreatic Cancer in Higher-Risk Patients: A PACGENE Study.
Author:	Childs, Erica J\|Chaffee, Kari G\|Gallinger, Steven\|Syngal, Sapna\|Schwartz, Ann G\|Cote, Michele L\|Bondy, Melissa L\|Hruban, Ralph H\|Chanock, Stephen J\|Hoover, Robert N\|Fuchs, Charles S\|Rider, David N\|Amundadottir, Laufey T\|Stolzenberg-Solomon, Rachael\|Wolpin
PMID:	27197284

41.
Journal:	Oncotarget. 2016 Nov 8;7(45):74227-74235.
Title:	Germline mutations in Japanese familial pancreatic cancer patients.
Author:	Takai, Erina\|Yachida, Shinichi\|Shimizu, Kyoko\|Furuse, Junji\|Kubo, Emi\|Ohmoto, Akihiro\|Suzuki, Masami\|Hruban, Ralph H\|Okusaka, Takuji\|Morizane, Chigusa\|Furukawa, Toru
PMID:	27732944

42.
Journal:	World J Gastroenterol. 2016 Aug 28;22(32):7275-88.
Title:	Perspectives on the combination of radiotherapy and targeted therapy with DNA repair inhibitors in the treatment of pancreatic cancer.
Author:	Yang, Shih-Hung\|Kuo, Ting-Chun\|Wu, Hsu\|Guo, Jhe-Cyuan\|Hsu, Chiun\|Hsu, Chih-Hung\|Tien, Yu-Wen\|Yeh, Kun-Huei\|Cheng, Ann-Lii\|Kuo, Sung-Hsin
PMID:	27621574

43.
Journal:	Hum Genet. 2016 Nov;135(11):1241-1249.
Title:	Multiple rare variants in high-risk pancreatic cancer-related genes may increase risk for pancreatic cancer in a subset of patients with and without germline CDKN2A mutations.
Author:	Yang, Xiaohong R\|Rotunno, Melissa\|Xiao, Yanzi\|Ingvar, Christian\|Helgadottir, Hildur\|Pastorino, Lorenza\|van Doorn, Remco\|Bennett, Hunter\|Graham, Cole\|Sampson, Joshua N\|Malasky, Michael\|Vogt, Aurelie\|Zhu, Bin\|Bianchi-Scarra, Giovanna\|Bruno, William\|Queirolo
PMID:	27449771

44.
Journal:	J Gastrointest Oncol. 2016 Apr;7(2):E6-E12.
Title:	Molecular profiling of a case of advanced pancreatic cancer identifies an active and tolerable combination of targeted therapy with backbone chemotherapy.
Author:	Johnson, Benny\|Vanderwalde, Ari\|Javadi, Nader\|Feldman, Rebecca\|Reddy, Sandeep Bobby
PMID:	27034805

45.
Journal:	Ann Surg Oncol. 2016 May;23(5):1729-35.
Title:	Statewide Retrospective Review of Familial Pancreatic Cancer in Delaware, and Frequency of Genetic Mutations in Pancreatic Cancer Kindreds.
Author:	Catts, Zohra Ali-Khan\|Baig, Muhammad Khurram\|Milewski, Becky\|Keywan, Christine\|Guarino, Michael\|Petrelli, Nicholas
PMID:	26727920

46.
Journal:	Cancer Discov. 2016 Feb;6(2):166-75.
Title:	Whole Genome Sequencing Defines the Genetic Heterogeneity of Familial Pancreatic Cancer.
Author:	Roberts, Nicholas J\|Norris, Alexis L\|Petersen, Gloria M\|Bondy, Melissa L\|Brand, Randall\|Gallinger, Steven\|Kurtz, Robert C\|Olson, Sara H\|Rustgi, Anil K\|Schwartz, Ann G\|Stoffel, Elena\|Syngal, Sapna\|Zogopoulos, George\|Ali, Syed Z\|Axilbund, Jennifer\|Chaffee,
PMID:	26658419

47.
Journal:	Cancer Epidemiol Biomarkers Prev. 2016 Jan;25(1):207-11.
Title:	Prevalence of Pathogenic Mutations in Cancer Predisposition Genes among Pancreatic Cancer Patients.
Author:	Hu, Chunling\|Hart, Steven N\|Bamlet, William R\|Moore, Raymond M\|Nandakumar, Kannabiran\|Eckloff, Bruce W\|Lee, Yean K\|Petersen, Gloria M\|McWilliams, Robert R\|Couch, Fergus J
PMID:	26483394

48.
Journal:	Ann Surg. 2016 Jan;263(1):153-61.
Title:	Reliable Detection of Somatic Mutations in Fine Needle Aspirates of Pancreatic Cancer With Next-generation Sequencing: Implications for Surgical Management.
Author:	Valero, Vicente 3rd\|Saunders, Tyler J\|He, Jin\|Weiss, Matthew J\|Cameron, John L\|Dholakia, Avani\|Wild, Aaron T\|Shin, Eun Ji\|Khashab, Mouen A\|O'Broin-Lennon, Anne Marie\|Ali, Syed Z\|Laheru, Daniel\|Hruban, Ralph H\|Iacobuzio-Donahue, Christine A\|Herman, Joseph
PMID:	26020105

49.
Journal:	Oncotarget. 2017 Apr 20;8(42):73240-73257.
Title:	Germline mutations in pancreatic cancer and potential new therapeutic options.
Author:	Pihlak, Rille\|Valle, Juan W\|McNamara, Mairead G
PMID:	29069866

50.
Journal:	Oncotarget. 2017 Dec 1;8(68):112893-112906.
Title:	Radiosensitization of the PI3K inhibitor HS-173 through reduction of DNA damage repair in pancreatic cancer.
Author:	Park, Jung Hee\|Jung, Kyung Hee\|Kim, Soo Jung\|Fang, Zhenghuan\|Yan, Hong Hua\|Son, Mi Kwon\|Kim, Juyoung\|Kang, Yeo Wool\|Lee, Ji Eun\|Han, Boreum\|Lim, Joo Han\|Hong, Soon-Sun
PMID:	29348875

51.
Journal:	Sheng Li Xue Bao. 2017 Dec 25;69(6):759-766.
Title:	Caveolin-1 is involved in DNA damage and repair signaling in X-irradiated Chang liver cells.
Author:	Li, Hong-Yan\|Qu, Chao\|Zhang, Ye-Jun\|Sun, Jia\|Han, Chao\|Liu, Jing\|Zou, Wei
PMID:	29270591

52.
Journal:	Sci Rep. 2017 Sep 11;7(1):11144.
Title:	ATM-deficiency increases genomic instability and metastatic potential in a mouse model of pancreatic cancer.
Author:	Drosos, Yiannis\|Escobar, David\|Chiang, Ming-Yi\|Roys, Kathryn\|Valentine, Virginia\|Valentine, Marc B\|Rehg, Jerold E\|Sahai, Vaibhav\|Begley, Lesa A\|Ye, Jianming\|Paul, Leena\|McKinnon, Peter J\|Sosa-Pineda, Beatriz
PMID:	28894253

53.
Journal:	Int J Mol Sci. 2017 Aug 31;18(9). pii: ijms18091886.
Title:	The Role of PALB2 in the DNA Damage Response and Cancer Predisposition.
Author:	Nepomuceno, Thales C\|De Gregoriis, Giuliana\|de Oliveira, Francisco M Bastos\|Suarez-Kurtz, Guilherme\|Monteiro, Alvaro N\|Carvalho, Marcelo A
PMID:	28858227

54.
Journal:	PLoS One. 2017 May 30;12(5):e0178221.
Title:	The G2 checkpoint inhibitor CBP-93872 increases the sensitivity of colorectal and pancreatic cancer cells to chemotherapy.
Author:	Iwata, Tsutomu\|Uchino, Tairin\|Koyama, Ayako\|Johmura, Yoshikazu\|Koyama, Kenichi\|Saito, Takuya\|Ishiguro, Seiji\|Arikawa, Takashi\|Komatsu, Shunichiro\|Miyachi, Masahiko\|Sano, Tsuyoshi\|Nakanishi, Makoto\|Shimada, Midori
PMID:	28558031

55.
Journal:	Cell Cycle. 2017 May 19;16(10):991-998.
Title:	Susceptibility of ATM-deficient pancreatic cancer cells to radiation.
Author:	Ayars, Michael\|Eshleman, James\|Goggins, Michael
PMID:	28453388

56.
Journal:	Oncotarget. 2017 Apr 18;8(16):26344-26355.
Title:	Poly (ADP-ribose) polymerase inhibitor, an effective radiosensitizer in lung and pancreatic cancers.
Author:	Hastak, Kedar\|Bhutra, Steven\|Parry, Renate\|Ford, James M
PMID:	28412751

57.
Journal:	Int J Biol Macromol. 2017 Sep;102:718-728.
Title:	The over expression of long non-coding RNA ANRIL promotes epithelial-mesenchymal transition by activating the ATM-E2F1 signaling pathway in pancreatic cancer: An in vivo and in vitro study.
Author:	Chen, Shi\|Zhang, Jia-Qiang\|Chen, Jiang-Zhi\|Chen, Hui-Xing\|Qiu, Fu-Nan\|Yan, Mao-Lin\|Chen, Yan-Ling\|Peng, Cheng-Hong\|Tian, Yi-Feng\|Wang, Yao-Dong
PMID:	28344092

58.
Journal:	J Gastrointest Oncol. 2017 Feb;8(1):164-172.
Title:	Potential actionable targets in appendiceal cancer detected by immunohistochemistry, fluorescent in situ hybridization, and mutational analysis.
Author:	Borazanci, Erkut\|Millis, Sherri Z\|Kimbrough, Jeffery\|Doll, Nancy\|Von Hoff, Daniel\|Ramanathan, Ramesh K
PMID:	28280620

59.
Journal:	J Clin Oncol. 2017 Oct 20;35(30):3382-3390.
Title:	Deleterious Germline Mutations in Patients With Apparently Sporadic Pancreatic Adenocarcinoma.
Author:	Shindo, Koji\|Yu, Jun\|Suenaga, Masaya\|Fesharakizadeh, Shahriar\|Cho, Christy\|Macgregor-Das, Anne\|Siddiqui, Abdulrehman\|Witmer, P Dane\|Tamura, Koji\|Song, Tae Jun\|Navarro Almario, Jose Alejandro\|Brant, Aaron\|Borges, Michael\|Ford, Madeline\|Barkley, Thomas\|He,
PMID:	28767289

60.
Journal:	Oncol Res Treat. 2018;41(10):619-625.
Title:	Targeting Defects in the Cellular DNA Damage Response for the Treatment of Pancreatic Ductal Adenocarcinoma.
Author:	Schmitt, Anna\|Feldmann, Georg\|Zander, Thomas\|Reinhardt, H Christian
PMID:	30286473

61.
Journal:	Gastrointest Endosc. 2018 Aug 23. pii: S0016-5107(18)32987-0.
Title:	Chronic pancreatitis changes in high-risk individuals for pancreatic ductal adenocarcinoma.
Author:	Thiruvengadam, Sushrut S\|Chuang, Judith\|Huang, Robert\|Girotra, Mohit\|Park, Walter G
PMID:	30145314

62.
Journal:	Pancreas. 2018 Sep;47(8):924-936.
Title:	Germline Variants and Risk for Pancreatic Cancer: A Systematic Review and Emerging Concepts.
Author:	Zhan, Wei\|Shelton, Celeste A\|Greer, Phil J\|Brand, Randall E\|Whitcomb, David C
PMID:	30113427

63.
Journal:	NPJ Genom Med. 2018 Jul 20;3:18.
Title:	Recurrent loss of heterozygosity correlates with clinical outcome in pancreatic neuroendocrine cancer.
Author:	Lawrence, Ben\|Blenkiron, Cherie\|Parker, Kate\|Tsai, Peter\|Fitzgerald, Sandra\|Shields, Paula\|Robb, Tamsin\|Yeong, Mee Ling\|Kramer, Nicole\|James, Sarah\|Black, Mik\|Fan, Vicky\|Poonawala, Nooriyah\|Yap, Patrick\|Coats, Esther\|Woodhouse, Braden\|Ramsaroop, Reena\|Yoz
PMID:	30062048

64.
Journal:	Genet Med. 2018 Jul 2. pii: 10.1038/s41436-018-0009-5.
Title:	Germline cancer susceptibility gene variants, somatic second hits, and survival outcomes in patients with resected pancreatic cancer.
Author:	Yurgelun, Matthew B\|Chittenden, Anu B\|Morales-Oyarvide, Vicente\|Rubinson, Douglas A\|Dunne, Richard F\|Kozak, Margaret M\|Qian, Zhi Rong\|Welch, Marisa W\|Brais, Lauren K\|Da Silva, Annacarolina\|Bui, Justin L\|Yuan, Chen\|Li, Tingting\|Li, Wanwan\|Masuda, Atsuhiro\|
PMID:	29961768

65.
Journal:	Clin Cancer Res. 2018 Jun 28. pii: 1078-0432.CCR-18-0531.
Title:	Molecular Profiling of Patients with Pancreatic Cancer: Initial Results from the Know Your Tumor Initiative.
Author:	Pishvaian, Michael J\|Bender, Robert J\|Halverson, David\|Rahib, Lola\|Hendifar, Andrew E\|Mikhail, Sameh\|Chung, Vincent\|Picozzi, Vincent J\|Sohal, Davendra\|Blais, Edik M\|Mason, Kimberly\|Lyons, Emily E\|Matrisian, Lynn M\|Brody, Jonathan R\|Madhavan, Subha\|Petrico
PMID:	29954777

66.
Journal:	JAMA. 2018 Jun 19;319(23):2401-2409.
Title:	Association Between Inherited Germline Mutations in Cancer Predisposition Genes and Risk of Pancreatic Cancer.
Author:	Hu, Chunling\|Hart, Steven N\|Polley, Eric C\|Gnanaolivu, Rohan\|Shimelis, Hermela\|Lee, Kun Y\|Lilyquist, Jenna\|Na, Jie\|Moore, Raymond\|Antwi, Samuel O\|Bamlet, William R\|Chaffee, Kari G\|DiCarlo, John\|Wu, Zhong\|Samara, Raed\|Kasi, Pashtoon M\|McWilliams, Robert R\|
PMID:	29922827

67.
Journal:	Oncotarget. 2018 Apr 13;9(28):19817-19825.
Title:	Association between homologous recombination repair gene mutations and response to oxaliplatin in pancreatic cancer.
Author:	Kondo, Tomohiro\|Kanai, Masashi\|Kou, Tadayuki\|Sakuma, Tomohiro\|Mochizuki, Hiroaki\|Kamada, Mayumi\|Nakatsui, Masahiko\|Uza, Norimitsu\|Kodama, Yuzo\|Masui, Toshihiko\|Takaori, Kyoichi\|Matsumoto, Shigemi\|Miyake, Hidehiko\|Okuno, Yasushi\|Muto, Manabu
PMID:	29731985

68.
Journal:	J Gastroenterol. 2018 Oct;53(10):1159-1167.
Title:	Germline variants in pancreatic cancer patients with a personal or family history of cancer fulfilling the revised Bethesda guidelines.
Author:	Ohmoto, Akihiro\|Morizane, Chigusa\|Kubo, Emi\|Takai, Erina\|Hosoi, Hiroko\|Sakamoto, Yasunari\|Kondo, Shunsuke\|Ueno, Hideki\|Shimada, Kazuaki\|Yachida, Shinichi\|Okusaka, Takuji
PMID:	29667044

69.
Journal:	Clin Cancer Res. 2018 Sep 15;24(18):4444-4454.
Title:	Integrated Genomic and Immunophenotypic Classification of Pancreatic Cancer Reveals Three Distinct Subtypes with Prognostic/Predictive Significance.
Author:	Wartenberg, Martin\|Cibin, Silvia\|Zlobec, Inti\|Vassella, Erik\|Eppenberger-Castori, Serenella\|Terracciano, Luigi\|Eichmann, Micha David\|Worni, Mathias\|Gloor, Beat\|Perren, Aurel\|Karamitopoulou, Eva
PMID:	29661773

70.
Journal:	Nat Commun. 2018 Apr 3;9(1):1317.
Title:	Multi-omics analysis reveals neoantigen-independent immune cell infiltration in copy-number driven cancers.
Author:	McGrail, Daniel J\|Federico, Lorenzo\|Li, Yongsheng\|Dai, Hui\|Lu, Yiling\|Mills, Gordon B\|Yi, Song\|Lin, Shiaw-Yih\|Sahni, Nidhi
PMID:	29615613

71.
Journal:	J Natl Cancer Inst. 2018 Feb 28. pii: 4915401.
Title:	Prospective Evaluation of Germline Alterations in Patients With Exocrine Pancreatic Neoplasms.
Author:	Lowery, Maeve A\|Wong, Winston\|Jordan, Emmet J\|Lee, Jonathan W\|Kemel, Yelena\|Vijai, Joseph\|Mandelker, Diana\|Zehir, Ahmet\|Capanu, Marinela\|Salo-Mullen, Erin\|Arnold, Angela G\|Yu, Kenneth H\|Varghese, Anna M\|Kelsen, David P\|Brenner, Robin\|Kaufmann, Erica\|Ravic
PMID:	29506128

72.
Journal:	BMC Complement Altern Med. 2018 Feb 20;18(1):71.
Title:	Anacardic acid inhibits pancreatic cancer cell growth, and potentiates chemotherapeutic effect by Chmp1A - ATM - p53 signaling pathway.
Author:	Park, Maiyon\|Upton, Danielle\|Blackmon, Melodie\|Dixon, Valerie\|Craver, Scott\|Neal, Dawn\|Perkins, Derek
PMID:	29463243

73.
Journal:	Oncol Lett. 2018 Feb;15(2):1943-1948.
Title:	Down-expression of poly(ADP-ribose) polymerase in p53-regulated pancreatic cancer cells.
Author:	Hou, Zhenyu\|Cui, Yunfeng\|Xing, Huizhi\|Mu, Xiaoyan
PMID:	29434894

74.
Journal:	Gastrointest Endosc. 2018 Jun;87(6):1443-1450.
Title:	Pancreatic cancer screening in high-risk individuals with germline genetic mutations.
Author:	DaVee, Tomas\|Coronel, Emmanuel\|Papafragkakis, Charilaos\|Thaiudom, Sayam\|Lanke, Gandhi\|Chakinala, Raja C\|Nogueras Gonzalez, Graciela M\|Bhutani, Manoop S\|Ross, William A\|Weston, Brian R\|Lee, Jeffrey H
PMID:	29309780

75.
Journal:	Fam Cancer. 2018 Jan;17(1):101-111.
Title:	Development of a high risk pancreatic screening clinic using 3.0 T MRI.
Author:	Barnes, Chad A\|Krzywda, Elizabeth\|Lahiff, Shannon\|McDowell, Dena\|Christians, Kathleen K\|Knechtges, Paul\|Tolat, Parag\|Hohenwalter, Mark\|Dua, Kulwinder\|Khan, Abdul H\|Evans, Douglas B\|Geurts, Jennifer\|Tsai, Susan
PMID:	29101607

76.
Journal:	Genet Med. 2018 Jan;20(1):119-127.
Title:	Prevalence of germ-line mutations in cancer genes among pancreatic cancer patients with a positive family history.
Author:	Chaffee, Kari G\|Oberg, Ann L\|McWilliams, Robert R\|Majithia, Neil\|Allen, Brian A\|Kidd, John\|Singh, Nanda\|Hartman, Anne-Renee\|Wenstrup, Richard J\|Petersen, Gloria M
PMID:	28726808

77.
Journal:	Fam Cancer. 2018 Apr;17(2):235-245.
Title:	The spectrum of genetic variants in hereditary pancreatic cancer includes Fanconi anemia genes.
Author:	Slavin, Thomas P\|Neuhausen, Susan L\|Nehoray, Bita\|Niell-Swiller, Mariana\|Solomon, Ilana\|Rybak, Christina\|Blazer, Kathleen\|Adamson, Aaron\|Yang, Kai\|Sand, Sharon\|Guerrero-Llamas, Nancy\|Castillo, Danielle\|Herzog, Josef\|Wu, Xiwei\|Tao, Shu\|Raja, Shivali\|Chung,
PMID:	28687971