Primary Site >> Liver Cancer

Gene >> ATM

Journal: Cancer Res. 1988 Sep 1;48(17):4848-54.
Title: Identification of a tumor-associated target antigen, ATM-1, for a human T-cell clone with activated killer activity and its existence in sera of cancer patients.
Author: Kaieda, T|Imawari, M|Yamasaki, Z|Ohnishi, S|Koike, M|Idezuki, Y|Takaku, F
PMID: 3044579
Journal: Hepatogastroenterology. 1999 May-Jun;46(27):1798-9.
Title: Early post-operative hyperbaric oxygen therapy modifies neutrophile activation.
Author: Ueno, S|Tanabe, G|Kihara, K|Aoki, D|Arikawa, K|Dogomori, H|Aikou, T
PMID: 10430348
Journal: Int J Cancer. 2001 Jul 15;93(2):288-93.
Title: Cancer risk in heterozygotes for ataxia-telangiectasia.
Author: Geoffroy-Perez, B|Janin, N|Ossian, K|Lauge, A|Croquette, M F|Griscelli, C|Debre, M|Bressac-de-Paillerets, B|Aurias, A|Stoppa-Lyonnet, D|Andrieu, N
PMID: 11410879
Journal: Lab Invest. 2003 May;83(5):643-54.
Title: Dysregulation of DNA repair pathways in a transforming growth factor alpha/c-myc transgenic mouse model of accelerated hepatocarcinogenesis.
Author: Hironaka, Koji|Factor, Valentina M|Calvisi, Diego F|Conner, Elizabeth A|Thorgeirsson, Snorri S
PMID: 12746474
Journal: Ai Zheng. 2003 Jul;22(7):680-5.
Title: [Determination of expression of eight p53-related genes in hepatocellular carcinoma with tissue microarrays].
Author: Zhu, Ming-Hua|Ni, Can-Rong|Zhu, Zhi|Li, Fang-Mei|Zhang, Shun-Min
PMID: 12866955
Journal: Exp Cell Res. 2005 Mar 10;304(1):1-15.
Title: The relative contribution of CHK1 and CHK2 to Adriamycin-induced checkpoint.
Author: Ho, Chui Chui|Siu, Wai Yi|Chow, Jeremy P H|Lau, Anita|Arooz, Talha|Tong, Hoi Yee|Ng, Irene O L|Poon, Randy Y C
PMID: 15707569
Journal: Eur J Cancer. 2006 Dec;42(18):3304-11.
Title: The effect of hyperbaric oxygen therapy on tumour growth in a mouse model of colorectal cancer liver metastases.
Author: Daruwalla, Jurstine|Christophi, Chris
PMID: 17010602
Journal: Proc Natl Acad Sci U S A. 2007 Aug 7;104(32):13028-33.
Title: Cellular senescence is an important mechanism of tumor regression upon c-Myc inactivation.
Author: Wu, Chi-Hwa|van Riggelen, Jan|Yetil, Alper|Fan, Alice C|Bachireddy, Pavan|Felsher, Dean W
PMID: 17664422
Journal: J Biol Chem. 2008 Sep 12;283(37):25455-67.
Title: Hepatitis B virus X protein via the p38MAPK pathway induces E2F1 release and ATR kinase activation mediating p53 apoptosis.
Author: Wang, Wen-Horng|Hullinger, Ronald L|Andrisani, Ourania M
PMID: 18606816
Journal: Zhonghua Yi Xue Za Zhi. 2009 Mar 31;89(12):800-4.
Title: [Nanogold inhibits angiogenesis and growth of liver cancer: experiment with mice].
Author: Pan, Yun-Long|Qiu, Si-Yuan|Qin, Li|Cai, Ji-Ye|Sun, Jia-Sheng
PMID: 19595116
Journal: Naunyn Schmiedebergs Arch Pharmacol. 2009 Nov;380(5):373-82.
Title: Tunicamycin induces resistance to camptothecin and etoposide in human hepatocellular carcinoma cells: role of cell-cycle arrest and GRP78.
Author: Hsu, Jui-Ling|Chiang, Po-Cheng|Guh, Jih-Hwa
PMID: 19777212
Journal: J Immunol. 2010 Dec 1;185(11):6985-98.
Title: Hepatitis C virus inhibits DNA damage repair through reactive oxygen and nitrogen species and by interfering with the ATM-NBS1/Mre11/Rad50 DNA repair pathway in monocytes and hepatocytes.
Author: Machida, Keigo|McNamara, George|Cheng, Kevin T-H|Huang, Jeffrey|Wang, Chun-Hsiang|Comai, Lucio|Ou, Jing-Hsiung James|Lai, Michael M C
PMID: 20974981
Journal: Cancer Lett. 2010 Feb 28;288(2):204-13.
Title: Butein induces G(2)/M phase arrest and apoptosis in human hepatoma cancer cells through ROS generation.
Author: Moon, Dong-Oh|Kim, Mun-Ock|Choi, Yung Hyun|Hyun, Jin Won|Chang, Weon Young|Kim, Gi-Young
PMID: 19643530
Journal: Langenbecks Arch Surg. 2011 Jan;396(1):99-106.
Title: Safety and efficacy of early postoperative hyperbaric oxygen therapy with restriction of transfusions in patients with HCC who have undergone partial hepatectomy.
Author: Ueno, Shinichi|Sakoda, Masahiko|Kurahara, Hiroshi|Iino, Satoshi|Minami, Koji|Ando, Kei|Mataki, Yukou|Maemura, Kosei|Ishigami, Sumiya|Shinchi, Hiroyuki|Natsugoe, Shoji
PMID: 21069381
Journal: Biochem Pharmacol. 2011 Mar 1;81(5):594-605.
Title: Autophagy inhibition enhances apoptosis triggered by BO-1051, an N-mustard derivative, and involves the ATM signaling pathway.
Author: Chen, Li-Hsin|Loong, Che-Chuan|Su, Tsann-Long|Lee, Yi-Jang|Chu, Pei-Ming|Tsai, Ming-Long|Tsai, Ping-Hsin|Tu, Pang-Hsien|Chi, Chin-Wen|Lee, Hsin-Chen|Chiou, Shih-Hwa
PMID: 21184746
Journal: Cell Cycle. 2011 Oct 15;10(20):3554-65.
Title: Dissection of cell context-dependent interactions between HBx and p53 family members in regulation of apoptosis: a role for HBV-induced HCC.
Author: Knoll, Susanne|Furst, Katharina|Thomas, Saijo|Villanueva Baselga, Sergio|Stoll, Anja|Schaefer, Stephanie|Putzer, Brigitte M
PMID: 22030623
Journal: J Med Virol. 2012 May;84(5):733-46.
Title: Hepatitis C virus promotes expression of the 3beta-hydroxysterol delta24-reductase through Sp1.
Author: Saito, Makoto|Kohara, Michinori|Tsukiyama-Kohara, Kyoko
PMID: 22431021
Journal: Biochem Biophys Res Commun. 2012 May 25;422(1):103-8.
Title: CGK733 enhances multinucleated cell formation and cytotoxicity induced by taxol in Chk1-deficient HBV-positive hepatocellular carcinoma cells.
Author: Wang, Huan|Zuo, Bin|Wang, Haibin|Ren, Laifeng|Yang, Peng|Zeng, Ming|Duan, Dan|Liu, Cong|Li, Mingyuan
PMID: 22564734
Journal: J Asian Nat Prod Res. 2012;14(7):657-64.
Title: Induction of cell cycle arrest by GL331 via triggering an ATM-dependent DNA damage response in HepG2 cells.
Author: Wang, Ya-Jie|Chen, Xiao-Guang|Xiao, Zhi-Yan|Liu, Geng-Tao|Sun, Hua
PMID: 22583615
Journal: Cancers (Basel). 2012 Apr 5;4(2):354-78.
Title: A New Player in the Development of TRAIL Based Therapies for Hepatocarcinoma Treatment: ATM Kinase.
Author: Stagni, Venturina|Santini, Simonetta|Barila, Daniela
PMID: 24213315
Journal: World J Gastroenterol. 2013 Dec 21;19(47):8873-9.
Title: Target genes discovery through copy number alteration analysis in human hepatocellular carcinoma.
Author: Gu, De-Leung|Chen, Yen-Hsieh|Shih, Jou-Ho|Lin, Chi-Hung|Jou, Yuh-Shan|Chen, Chian-Feng
PMID: 24379610
Journal: Biochimie. 2014 Aug;103:118-25.
Title: CCT128930 induces cell cycle arrest, DNA damage, and autophagy independent of Akt inhibition.
Author: Wang, Feng-Ze|Chang, Zheng-Yao|Fei, Hong-Rong|Yang, Ming-Feng|Yang, Xiao-Yi|Sun, Bao-Liang
PMID: 24793486
Journal: BMC Cancer. 2014 Dec 19;14:987.
Title: SC-III3, a novel scopoletin derivative, induces cytotoxicity in hepatocellular cancer cells through oxidative DNA damage and ataxia telangiectasia-mutated nuclear protein kinase activation.
Author: Zhao, Peng|Chen, Li|Li, Lin-Hu|Wei, Zhi-Feng|Tong, Bei|Jia, Yu-Gai|Kong, Ling-Yi|Xia, Yu-Feng|Dai, Yue
PMID: 25527123
Journal: Food Funct. 2014 Dec;5(12):3320-8.
Title: Piper betle leaf extracts induced human hepatocellular carcinoma Hep3B cell death via MAPKs regulating the p73 pathway in vitro and in vivo.
Author: Wu, Pei-Fang|Tseng, Hsien-Chun|Chyau, Charng-Cherng|Chen, Jing-Hsien|Chou, Fen-Pi
PMID: 25371988
Journal: Chem Biol Interact. 2014 Aug 5;219:184-94.
Title: Hellebrigenin induces cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells through inhibition of Akt.
Author: Deng, Li-Juan|Hu, Li-Ping|Peng, Qun-Long|Yang, Xiao-Lin|Bai, Liang-Liang|Yiu, Anita|Li, Yong|Tian, Hai-Yan|Ye, Wen-Cai|Zhang, Dong-Mei
PMID: 24954031
Journal: Oncotarget. 2014 May 30;5(10):3012-22.
Title: Identification of novel therapeutic targets in the PI3K/AKT/mTOR pathway in hepatocellular carcinoma using targeted next generation sequencing.
Author: Janku, Filip|Kaseb, Ahmed O|Tsimberidou, Apostolia M|Wolff, Robert A|Kurzrock, Razelle
PMID: 24931142
Journal: Asian Pac J Cancer Prev. 2014;15(17):7043-8.
Title: Hsp90 inhibitor geldanamycin enhances the antitumor efficacy of enediyne lidamycin in association with reduced DNA damage repair.
Author: Han, Fei-Fei|Li, Liang|Shang, Bo-Yang|Shao, Rong-Guang|Zhen, Yong-Su
PMID: 25227788
Journal: Arch Toxicol. 2015 Jun;89(6):967-77.
Title: Mechanistic relationships between hepatic genotoxicity and carcinogenicity in male B6C3F1 mice treated with polycyclic aromatic hydrocarbon mixtures.
Author: Phillips, Tracie D|Richardson, Molly|Cheng, Yi-Shing Lisa|He, Lingyu|McDonald, Thomas J|Cizmas, Leslie H|Safe, Stephen H|Donnelly, Kirby C|Wang, Fen|Moorthy, Bhagavatula|Zhou, Guo-Dong
PMID: 24888377
Journal: Curr Cancer Drug Targets. 2015;15(6):533-41.
Title: A novel NGR-conjugated peptide targets DNA damage responses for radiosensitization.
Author: Ma, Jinlu|Zhang, Dan|Ying, Xia|Zhao, Ying|He, Chenchen|Zhu, Qing|Han, Suxia
PMID: 25850444
Journal: PLoS One. 2015 Apr 15;10(4):e0123333.
Title: Reptin regulates DNA double strand breaks repair in human hepatocellular carcinoma.
Author: Raymond, Anne-Aurelie|Benhamouche, Samira|Neaud, Veronique|Di Martino, Julie|Javary, Joaquim|Rosenbaum, Jean
PMID: 25875766
Journal: Chem Res Toxicol. 2015 Nov 16;28(11):2160-9.
Title: Polychlorinated Biphenyl Quinone Metabolite Promotes p53-Dependent DNA Damage Checkpoint Activation, S-Phase Cycle Arrest and Extrinsic Apoptosis in Human Liver Hepatocellular Carcinoma HepG2 Cells.
Author: Song, Xiufang|Li, Lingrui|Shi, Qiong|Lehmler, Hans-Joachim|Fu, Juanli|Su, Chuanyang|Xia, Xiaomin|Song, Erqun|Song, Yang
PMID: 26451628
Journal: Sci Rep. 2015 Nov 3;5:16185.
Title: Ailanthone Inhibits Huh7 Cancer Cell Growth via Cell Cycle Arrest and Apoptosis In Vitro and In Vivo.
Author: Zhuo, Zhenjian|Hu, Jianyang|Yang, Xiaolin|Chen, Minfen|Lei, Xueping|Deng, Lijuan|Yao, Nan|Peng, Qunlong|Chen, Zhesheng|Ye, Wencai|Zhang, Dongmei
PMID: 26525771
Journal: Oncotarget. 2016 Dec 27;7(52):85832-85847.
Title: Clock gene Per2 as a controller of liver carcinogenesis.
Author: Mteyrek, Ali|Filipski, Elisabeth|Guettier, Catherine|Okyar, Alper|Levi, Francis
PMID: 27494874
Journal: Oncotarget. 2016 Apr 5;7(14):18896-905.
Title: Exogenous p53 and ASPP2 expression enhances rAdV-TK/ GCV-induced death in hepatocellular carcinoma cells lacking functional p53.
Author: Liu, Xiuhong|Wang, Shuang|Guo, Xianghua|Wei, Feili|Yin, Jiming|Zang, Yunjin|Li, Ning|Chen, Dexi
PMID: 26934443
Journal: BMC Complement Altern Med. 2017 Jan 19;17(1):62.
Title: Sinularin induces DNA damage, G2/M phase arrest, and apoptosis in human hepatocellular carcinoma cells.
Author: Chung, Ting-Wen|Lin, Shih-Chao|Su, Jui-Hsin|Chen, Yu-Kuo|Lin, Chi-Chien|Chan, Hong-Lin
PMID: 28103869
Journal: Cancer Cell Int. 2017 Apr 26;17:49.
Title: pATM and gammaH2AX are effective radiation biomarkers in assessing the radiosensitivity of (12)C(6+) in human tumor cells.
Author: Zhao, Jin|Guo, Zhong|Pei, Shuyan|Song, Lei|Wang, Chenjing|Ma, Jianxiu|Jin, Long|Ma, Yanqing|He, Renke|Zhong, Jianbin|Ma, Ying|Zhang, Hong
PMID: 28450809
Journal: Int J Med Sci. 2017 Apr 9;14(6):523-529.
Title: Synergistic Antitumor Effect of Sorafenib in Combination with ATM Inhibitor in Hepatocellular Carcinoma Cells.
Author: Liu, Jianhua|Liu, Yahui|Meng, Lingyu|Ji, Bai|Yang, Daqing
PMID: 28638267
Journal: Sci Rep. 2017 Aug 30;7(1):9989.
Title: XWL-1-48 exerts antitumor activity via targeting topoisomerase II and enhancing degradation of Mdm2 in human hepatocellular carcinoma.
Author: Wang, Yajie|Sun, Hua|Xiao, Zhiyan|Zhang, Dan|Bao, Xiuqi|Wei, Ning
PMID: 28855652
Journal: Biochem Biophys Res Commun. 2018 Jan 22;495(4):2566-2572.
Title: Knockdown of AMPKalpha decreases ATM expression and increases radiosensitivity under hypoxia and nutrient starvation in an SV40-transformed human fibroblast cell line, LM217.
Author: Murata, Yasuhiko|Hashimoto, Takuma|Urushihara, Yusuke|Shiga, Soichiro|Takeda, Kazuya|Jingu, Keiichi|Hosoi, Yoshio
PMID: 29284117
Journal: Exp Mol Pathol. 2018 Feb;104(1):45-49.
Title: Alcoholic hepatitis versus non-alcoholic steatohepatitis: Levels of expression of some proteins involved in tumorigenesis.
Author: Nguyen, Luan|Masouminia, Maryam|Mendoza, Alejandro|Samadzadeh, Sara|Tillman, Brittany|Morgan, Timothy|French, Barbara|French, Samuel
PMID: 29307797
Journal: Bioconjug Chem. 2018 Jun 20;29(6):2039-2049.
Title: Rational Design of Cancer-Targeted Selenadiazole Derivative as Efficient Radiosensitizer for Precise Cancer Therapy.
Author: Zeng, Delong|Deng, Shulin|Sang, Chengcheng|Zhao, Jianfu|Chen, Tianfeng
PMID: 29771500
Journal: Acta Pharmacol Sin. 2018 Jun 19. pii: 10.1038/s41401-018-0047-1.
Title: Aescin-induced reactive oxygen species play a pro-survival role in human cancer cells via ATM/AMPK/ULK1-mediated autophagy.
Author: Li, Bin|Wu, Guo-Liang|Dai, Wei|Wang, Gang|Su, Hao-Yuan|Shen, Xue-Ping|Zhan, Rui|Xie, Jia-Ming|Wang, Zhong|Qin, Zheng-Hong|Gao, Quan-Gen|Shen, Gen-Hai
PMID: 29921885