Primary Site >> Liver Cancer
Gene >> ATM
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Ref: Identification of a tumor-associated target antigen, ATM-1, for a human T-cell clone with activated killer activity and its existence in sera of cancer patients. PMID: 3044579 |
Ref: Early post-operative hyperbaric oxygen therapy modifies neutrophile activation. PMID: 10430348 |
Ref: Cancer risk in heterozygotes for ataxia-telangiectasia. PMID: 11410879 |
Ref: Dysregulation of DNA repair pathways in a transforming growth factor alpha/c-myc transgenic mouse model of accelerated hepatocarcinogenesis. PMID: 12746474 Ref: [Determination of expression of eight p53-related genes in hepatocellular carcinoma with tissue microarrays]. PMID: 12866955 |
Ref: The relative contribution of CHK1 and CHK2 to Adriamycin-induced checkpoint. PMID: 15707569 |
Ref: The effect of hyperbaric oxygen therapy on tumour growth in a mouse model of colorectal cancer liver metastases. PMID: 17010602 |
Ref: Cellular senescence is an important mechanism of tumor regression upon c-Myc inactivation. PMID: 17664422 |
Ref: Hepatitis B virus X protein via the p38MAPK pathway induces E2F1 release and ATR kinase activation mediating p53 apoptosis. PMID: 18606816 |
Ref: [Nanogold inhibits angiogenesis and growth of liver cancer: experiment with mice]. PMID: 19595116 Ref: Tunicamycin induces resistance to camptothecin and etoposide in human hepatocellular carcinoma cells: role of cell-cycle arrest and GRP78. PMID: 19777212 |
Ref: Butein induces G(2)/M phase arrest and apoptosis in human hepatoma cancer cells through ROS generation. PMID: 19643530 Ref: Hepatitis C virus inhibits DNA damage repair through reactive oxygen and nitrogen species and by interfering with the ATM-NBS1/Mre11/Rad50 DNA repair pathway in monocytes and hepatocytes. PMID: 20974981 |
Ref: Safety and efficacy of early postoperative hyperbaric oxygen therapy with restriction of transfusions in patients with HCC who have undergone partial hepatectomy. PMID: 21069381 Ref: Autophagy inhibition enhances apoptosis triggered by BO-1051, an N-mustard derivative, and involves the ATM signaling pathway. PMID: 21184746 Ref: Dissection of cell context-dependent interactions between HBx and p53 family members in regulation of apoptosis: a role for HBV-induced HCC. PMID: 22030623 |
Ref: Hepatitis C virus promotes expression of the 3beta-hydroxysterol delta24-reductase through Sp1. PMID: 22431021 Ref: CGK733 enhances multinucleated cell formation and cytotoxicity induced by taxol in Chk1-deficient HBV-positive hepatocellular carcinoma cells. PMID: 22564734 Ref: Induction of cell cycle arrest by GL331 via triggering an ATM-dependent DNA damage response in HepG2 cells. PMID: 22583615 Ref: A New Player in the Development of TRAIL Based Therapies for Hepatocarcinoma Treatment: ATM Kinase. PMID: 24213315 |
Ref: Target genes discovery through copy number alteration analysis in human hepatocellular carcinoma. PMID: 24379610 |
Ref: CCT128930 induces cell cycle arrest, DNA damage, and autophagy independent of Akt inhibition. PMID: 24793486 Ref: Identification of novel therapeutic targets in the PI3K/AKT/mTOR pathway in hepatocellular carcinoma using targeted next generation sequencing. PMID: 24931142 Ref: Hellebrigenin induces cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells through inhibition of Akt. PMID: 24954031 Ref: Hsp90 inhibitor geldanamycin enhances the antitumor efficacy of enediyne lidamycin in association with reduced DNA damage repair. PMID: 25227788 Ref: Piper betle leaf extracts induced human hepatocellular carcinoma Hep3B cell death via MAPKs regulating the p73 pathway in vitro and in vivo. PMID: 25371988 Ref: SC-III3, a novel scopoletin derivative, induces cytotoxicity in hepatocellular cancer cells through oxidative DNA damage and ataxia telangiectasia-mutated nuclear protein kinase activation. PMID: 25527123 |
Ref: Mechanistic relationships between hepatic genotoxicity and carcinogenicity in male B6C3F1 mice treated with polycyclic aromatic hydrocarbon mixtures. PMID: 24888377 Ref: A novel NGR-conjugated peptide targets DNA damage responses for radiosensitization. PMID: 25850444 Ref: Reptin regulates DNA double strand breaks repair in human hepatocellular carcinoma. PMID: 25875766 Ref: Polychlorinated Biphenyl Quinone Metabolite Promotes p53-Dependent DNA Damage Checkpoint Activation, S-Phase Cycle Arrest and Extrinsic Apoptosis in Human Liver Hepatocellular Carcinoma HepG2 Cells. PMID: 26451628 Ref: Ailanthone Inhibits Huh7 Cancer Cell Growth via Cell Cycle Arrest and Apoptosis In Vitro and In Vivo. PMID: 26525771 |
Ref: Exogenous p53 and ASPP2 expression enhances rAdV-TK/ GCV-induced death in hepatocellular carcinoma cells lacking functional p53. PMID: 26934443 Ref: Clock gene Per2 as a controller of liver carcinogenesis. PMID: 27494874 |
Ref: Sinularin induces DNA damage, G2/M phase arrest, and apoptosis in human hepatocellular carcinoma cells. PMID: 28103869 Ref: pATM and gammaH2AX are effective radiation biomarkers in assessing the radiosensitivity of (12)C(6+) in human tumor cells. PMID: 28450809 Ref: Synergistic Antitumor Effect of Sorafenib in Combination with ATM Inhibitor in Hepatocellular Carcinoma Cells. PMID: 28638267 Ref: XWL-1-48 exerts antitumor activity via targeting topoisomerase II and enhancing degradation of Mdm2 in human hepatocellular carcinoma. PMID: 28855652 |
Ref: Knockdown of AMPKalpha decreases ATM expression and increases radiosensitivity under hypoxia and nutrient starvation in an SV40-transformed human fibroblast cell line, LM217. PMID: 29284117 Ref: Alcoholic hepatitis versus non-alcoholic steatohepatitis: Levels of expression of some proteins involved in tumorigenesis. PMID: 29307797 Ref: Rational Design of Cancer-Targeted Selenadiazole Derivative as Efficient Radiosensitizer for Precise Cancer Therapy. PMID: 29771500 Ref: Aescin-induced reactive oxygen species play a pro-survival role in human cancer cells via ATM/AMPK/ULK1-mediated autophagy. PMID: 29921885 |