Literatures

Primary Site >> Colorectal Cancer

Gene >> ATM

1.
Journal:	Arch Pathol Lab Med. 1990 Aug;114(8):855-7.
Title:	A rapid and simple in vitro method for evaluating human colorectal epithelial proliferation.
Author:	Darmon, E\|Pincu-Hornstein, A\|Rozen, P
PMID:	1695838

2.
Journal:	Oncogene. 1997 Nov 27;15(22):2659-65.
Title:	Influence of ATM function on telomere metabolism.
Author:	Smilenov, L B\|Morgan, S E\|Mellado, W\|Sawant, S G\|Kastan, M B\|Pandita, T K
PMID:	9400992

3.
Journal:	Oncol Rep. 1999 May-Jun;6(3):655-8.
Title:	Loss of heterozygosity at the ATM locus in colorectal carcinoma.
Author:	Uhrhammer, N\|Bay, J\|Pernin, D\|Rio, P\|Grancho, M\|Kwiatkowski, F\|Gosse-Brun, S\|Daver, A\|Bignon, Y
PMID:	10203610

4.
Journal:	Mol Cell Biol. 1999 Oct;19(10):6963-71.
Title:	Altered telomere nuclear matrix interactions and nucleosomal periodicity in ataxia telangiectasia cells before and after ionizing radiation treatment.
Author:	Smilenov, L B\|Dhar, S\|Pandita, T K
PMID:	10490633

5.
Journal:	Int J Cancer. 2000 Apr 15;86(2):262-8.
Title:	Aberrant splicing of the ATM gene associated with shortening of the intronic mononucleotide tract in human colon tumor cell lines: a novel mutation target of microsatellite instability.
Author:	Ejima, Y\|Yang, L\|Sasaki, M S
PMID:	10738255

6.
Journal:	Radiat Res. 2000 Aug;154(2):133-9.
Title:	Influence of ATM function on interactions between telomeres and nuclear matrix.
Author:	Pandita, T K\|Dhar, S
PMID:	10931683

7.
Journal:	Int J Cancer. 2000 Dec 15;88(6):928-31.
Title:	A polymorphism in the ATM gene modulates the penetrance of hereditary non-polyposis colorectal cancer.
Author:	Maillet, P\|Chappuis, P O\|Vaudan, G\|Dobbie, Z\|Muller, H\|Hutter, P\|Sappino, A P
PMID:	11093816

8.
Journal:	Cancer Lett. 2001 Jun 10;167(1):91-7.
Title:	Methylation of the hMLH1, p16, and MDR1 genes in colorectal carcinoma: associations with clinicopathological features.
Author:	Shannon, B A\|Iacopetta, B J
PMID:	11323103

9.
Journal:	Int J Cancer. 2001 Jul 15;93(2):288-93.
Title:	Cancer risk in heterozygotes for ataxia-telangiectasia.
Author:	Geoffroy-Perez, B\|Janin, N\|Ossian, K\|Lauge, A\|Croquette, M F\|Griscelli, C\|Debre, M\|Bressac-de-Paillerets, B\|Aurias, A\|Stoppa-Lyonnet, D\|Andrieu, N
PMID:	11410879

10.
Journal:	Oncogene. 2001 Sep 20;20(42):6095-101.
Title:	Frequent allelic imbalance at the ATM locus in DNA multiploid colorectal carcinomas.
Author:	Sugai, T\|Habano, W\|Uesugi, N\|Jiao, Y F\|Nakamura, S I\|Yoshida, T\|Higuchi, T
PMID:	11593417

11.
Journal:	Leuk Lymphoma. 2001 Jul;42(3):517-20.
Title:	Analysis of the CHK2 gene in lymphoid malignancies.
Author:	Tavor, S\|Takeuchi, S\|Tsukasaki, K\|Miller, C W\|Hofmann, W K\|Ikezoe, T\|Said, J W\|Koeffler, H P
PMID:	11699418

12.
Journal:	EMBO Rep. 2002 Mar;3(3):248-54. Epub 2002 Feb 15.
Title:	Human MRE11 is inactivated in mismatch repair-deficient cancers.
Author:	Giannini, Giuseppe\|Ristori, Elisabetta\|Cerignoli, Fabio\|Rinaldi, Christian\|Zani, Massimo\|Viel, Alessandra\|Ottini, Laura\|Crescenzi, Marco\|Martinotti, Stefano\|Bignami, Margherita\|Frati, Luigi\|Screpanti, Isabella\|Gulino, Alberto
PMID:	11850399

13.
Journal:	Oncogene. 2002 May 30;21(24):3864-71.
Title:	Aberrant methylation of the ATM promoter correlates with increased radiosensitivity in a human colorectal tumor cell line.
Author:	Kim, Wan-ju\|Vo, Quynh N\|Shrivastav, Meena\|Lataxes, Tamara A\|Brown, Kevin D
PMID:	12032824

14.
Journal:	J Biol Chem. 2002 Oct 11;277(41):38222-9.
Title:	ATM is activated in response to N-methyl-N'-nitro-N-nitrosoguanidine-induced DNA alkylation.
Author:	Adamson, Aaron W\|Kim, Wan-Ju\|Shangary, Sanjeev\|Baskaran, R\|Brown, Kevin D
PMID:	12151394

15.
Journal:	Int J Oncol. 2003 Mar;22(3):663-70.
Title:	Gene expression profile of metastatic colon cancer cells resistant to cisplatin-induced apoptosis.
Author:	Huerta, Sergio\|Harris, Diane M\|Jazirehi, Ali\|Bonavida, Benjamin\|Elashoff, David\|Livingston, Edward H\|Heber, David
PMID:	12579322

16.
Journal:	Hum Mutat. 2003 May;21(5):535-41.
Title:	Detection of hotspot mutations and polymorphisms using an enhanced PCR-RFLP approach.
Author:	Liu, W H\|Kaur, M\|Makrigiorgos, G M
PMID:	12673796

17.
Journal:	Br J Cancer. 2003 Oct 20;89(8):1559-65.
Title:	Brostallicin (PNU-166196)--a new DNA minor groove binder that retains sensitivity in DNA mismatch repair-deficient tumour cells.
Author:	Fedier, A\|Fowst, C\|Tursi, J\|Geroni, C\|Haller, U\|Marchini, S\|Fink, D
PMID:	14562032

18.
Journal:	Int J Colorectal Dis. 2004 Jan;19(1):49-54.
Title:	DNA variants in the ATM gene are not associated with sporadic rectal cancer in a Norwegian population-based study.
Author:	Kristensen, Annette Torgunrud\|Bjorheim, Jens\|Wiig, Johan\|Giercksky, Karl E\|Ekstrom, Per O
PMID:	12827413

19.
Journal:	Oncogene. 2004 Jun 24;23(29):4984-92.
Title:	Induction of S-phase arrest and p21 overexpression by a small molecule 2[[3-(2,3-dichlorophenoxy)propyl] amino]ethanol in correlation with activation of ERK.
Author:	Zhu, Hongbo\|Zhang, Lidong\|Wu, Shuhong\|Teraishi, Fuminori\|Davis, John J\|Jacob, Dietmar\|Fang, Bingliang
PMID:	15122344

20.
Journal:	Environ Mol Mutagen. 2004;44(1):3-9.
Title:	Nitric oxide and p53 in cancer-prone chronic inflammation and oxyradical overload disease.
Author:	Goodman, Julie E\|Hofseth, Lorne J\|Hussain, S Perwez\|Harris, Curtis C
PMID:	15199542

21.
Journal:	Breast Cancer Res. 2004;6(4):R366-71. Epub 2004 May 14.
Title:	No germline mutations in the histone acetyltransferase gene EP300 in BRCA1 and BRCA2 negative families with breast cancer and gastric, pancreatic, or colorectal cancer.
Author:	Campbell, Ian G\|Choong, David\|Chenevix-Trench, Georgia
PMID:	15217503

22.
Journal:	J Biol Chem. 2004 Sep 17;279(38):39584-92. Epub 2004 Jul 20.
Title:	ATM-dependent CHK2 activation induced by anticancer agent, irofulven.
Author:	Wang, Jian\|Wiltshire, Timothy\|Wang, Yutian\|Mikell, Carmenza\|Burks, Julian\|Cunningham, Cynthia\|Van Laar, Emily S\|Waters, Stephen J\|Reed, Eddie\|Wang, Weixin
PMID:	15269203

23.
Journal:	Cell Cycle. 2004 Sep;3(9):1177-81. Epub 2004 Sep 13.
Title:	Chk1, but not Chk2, is involved in the cellular response to DNA damaging agents: differential activity in cells expressing or not p53.
Author:	Carrassa, Laura\|Broggini, Massimo\|Erba, Eugenio\|Damia, Giovanna
PMID:	15326376

24.
Journal:	Mol Cancer Ther. 2004 Sep;3(9):1147-57.
Title:	CHK1 and CHK2 are differentially involved in mismatch repair-mediated 6-thioguanine-induced cell cycle checkpoint responses.
Author:	Yan, Tao\|Desai, Anand B\|Jacobberger, James W\|Sramkoski, R Michael\|Loh, Tamalette\|Kinsella, Timothy J
PMID:	15367709

25.
Journal:	Cancer Res. 2004 Sep 15;64(18):6588-94.
Title:	5-fluoro-2'-deoxyuridine-induced cdc25A accumulation correlates with premature mitotic entry and clonogenic death in human colon cancer cells.
Author:	Parsels, Leslie Anne\|Parsels, Joshua David\|Tai, Daniel Chung-Ho\|Coughlin, Daniel James\|Maybaum, Jonathan
PMID:	15374972

26.
Journal:	Int J Cancer. 2004 Dec 10;112(5):846-53.
Title:	Promoter hypermethylation of tumor-related genes in the progression of colorectal neoplasia.
Author:	Bai, Alfa H C\|Tong, Joanna H M\|To, Ka-Fai\|Chan, Michael W Y\|Man, Ellen P S\|Lo, Kwok-Wai\|Lee, Janet F Y\|Sung, Joseph J Y\|Leung, Wai K
PMID:	15386372

27.
Journal:	J Natl Cancer Inst. 2005 Jun 1;97(11):813-22.
Title:	Cancer risks and mortality in heterozygous ATM mutation carriers.
Author:	Thompson, Deborah\|Duedal, Silvia\|Kirner, Jennifer\|McGuffog, Lesley\|Last, James\|Reiman, Anne\|Byrd, Philip\|Taylor, Malcolm\|Easton, Douglas F
PMID:	15928302

28.
Journal:	Oncol Rep. 2005 Aug;14(2):313-7.
Title:	ATM expression in rectal cancers with or without preoperative radiotherapy.
Author:	Arlehag, Linda\|Adell, Gunnar\|Knutsen, Annica\|Thorstenson, Sten\|Sun, Xiao-Feng
PMID:	16012708

29.
Journal:	Cancer Causes Control. 2005 Aug;16(6):749-53.
Title:	ATM polymorphism and hereditary nonpolyposis colorectal cancer (HNPCC) age of onset (United States).
Author:	Jones, J Shawn\|Gu, Xiangjun\|Lynch, Patrick M\|Rodriguez-Bigas, Miguel\|Amos, Christopher I\|Frazier, Marsha L
PMID:	16049814

30.
Journal:	Biochim Biophys Acta. 2006 Jan;1765(1):67-73. Epub 2005 Oct 6.
Title:	CtIP, a candidate tumor susceptibility gene is a team player with luminaries.
Author:	Chinnadurai, G
PMID:	16249056

31.
Journal:	Nucleic Acids Res. 2006 Feb 2;34(3):880-92. Print 2006.
Title:	Haploinsufficiency of the Mus81-Eme1 endonuclease activates the intra-S-phase and G2/M checkpoints and promotes rereplication in human cells.
Author:	Hiyama, Takashi\|Katsura, Mari\|Yoshihara, Takashi\|Ishida, Mari\|Kinomura, Aiko\|Tonda, Tetsuji\|Asahara, Toshimasa\|Miyagawa, Kiyoshi
PMID:	16456034

32.
Journal:	Clin Cancer Res. 2006 Mar 1;12(5):1494-500.
Title:	Expression of DNA double-strand break repair proteins ATM and BRCA1 predicts survival in colorectal cancer.
Author:	Grabsch, Heike\|Dattani, Mit\|Barker, Lisa\|Maughan, Nicola\|Maude, Karen\|Hansen, Olaf\|Gabbert, Helmut E\|Quirke, Phil\|Mueller, Wolfram
PMID:	16533773

33.
Journal:	Int J Radiat Biol. 2006 Apr;82(4):277-83.
Title:	Radiosensitization of tumor cells by modulation of ATM kinase.
Author:	Choi, Eun Kyung\|Ji, In Mi\|Lee, So Ryung\|Kook, Yeon Hee\|Griffin, Robert J\|Lim, Byung Uk\|Kim, Jin-Seok\|Lee, Doo Sung\|Song, Chang Won\|Park, Heon Joo
PMID:	16690595

34.
Journal:	J Biol Chem. 2006 Oct 13;281(41):30814-23. Epub 2006 Aug 10.
Title:	Defective Mre11-dependent activation of Chk2 by ataxia telangiectasia mutated in colorectal carcinoma cells in response to replication-dependent DNA double strand breaks.
Author:	Takemura, Haruyuki\|Rao, V Ashutosh\|Sordet, Olivier\|Furuta, Takahisa\|Miao, Ze-Hong\|Meng, Linghua\|Zhang, Hongliang\|Pommier, Yves
PMID:	16905549

35.
Journal:	Gastroenterology. 2006 Sep;131(3):841-52.
Title:	Recruitment of ataxia-telangiectasia mutated to the p21(waf1) promoter by ZBP-89 plays a role in mucosal protection.
Author:	Bai, Longchuan\|Kao, John Y\|Law, David J\|Merchant, Juanita L
PMID:	16952553

36.
Journal:	Hum Mol Genet. 2006 Nov 1;15(21):3263-71.
Title:	Search for low penetrance alleles for colorectal cancer through a scan of 1467 non-synonymous SNPs in 2575 cases and 2707 controls with validation by kin-cohort analysis of 14 704 first-degree relatives.
Author:	Webb, Emily L\|Rudd, Matthew F\|Sellick, Gabrielle S\|El Galta, Rachid\|Bethke, Lara\|Wood, Wendy\|Fletcher, Olivia\|Penegar, Steven\|Withey, Laura\|Qureshi, Mobshra\|Johnson, Nichola\|Tomlinson, Ian\|Gray, Richard\|Peto, Julian\|Houlston, Richard S
PMID:	17000706

37.
Journal:	Clin Cancer Res. 2006 Nov 1;12(21):6532-9.
Title:	2-methoxyestradiol, an endogenous mammalian metabolite, radiosensitizes colon carcinoma cells through c-Jun NH2-terminal kinase activation.
Author:	Zou, HuiChao\|Adachi, Masaaki\|Imai, Kohzoh\|Hareyama, Masato\|Yoshioka, Katsuji\|Zhao, Shiguang\|Shinomura, Yasuhisa
PMID:	17085668

38.
Journal:	Oncogene. 2007 Mar 1;26(10):1449-58. Epub 2006 Aug 28.
Title:	The Wip1 phosphatase (PPM1D) antagonizes activation of the Chk2 tumour suppressor kinase.
Author:	Oliva-Trastoy, M\|Berthonaud, V\|Chevalier, A\|Ducrot, C\|Marsolier-Kergoat, M-C\|Mann, C\|Leteurtre, F
PMID:	16936775

39.
Journal:	J Mol Med (Berl). 2007 Mar;85(3):293-304. Epub 2006 Dec 2.
Title:	Array CGH identifies distinct DNA copy number profiles of oncogenes and tumor suppressor genes in chromosomal- and microsatellite-unstable sporadic colorectal carcinomas.
Author:	Lassmann, Silke\|Weis, Roland\|Makowiec, Frank\|Roth, Jasmine\|Danciu, Mihai\|Hopt, Ulrich\|Werner, Martin
PMID:	17143621

40.
Journal:	J Pathol. 2007 Mar;211(4):471-80.
Title:	Evidence for the receipt of DNA damage stimuli by PML nuclear domains.
Author:	Varadaraj, A\|Dovey, C L\|Laredj, L\|Ferguson, B\|Alexander, C E\|Lubben, N\|Wyllie, A H\|Rich, T
PMID:	17206596

41.
Journal:	Gastroenterology. 2007 Jan;132(1):221-35.
Title:	5-ASA affects cell cycle progression in colorectal cells by reversibly activating a replication checkpoint.
Author:	Luciani, M Gloria\|Campregher, Christoph\|Fortune, John M\|Kunkel, Thomas A\|Gasche, Christoph
PMID:	17241873

42.
Journal:	Cancer Biol Ther. 2007 Mar;6(3):367-76. Epub 2007 Mar 13.
Title:	Basic transcription factor 3 (BTF3) regulates transcription of tumor-associated genes in pancreatic cancer cells.
Author:	Kusumawidjaja, Grace\|Kayed, Hany\|Giese, Nathalia\|Bauer, Andrea\|Erkan, Mert\|Giese, Thomas\|Hoheise, Jorg D\|Friess, Helmut\|Kleeff, Jorg
PMID:	17312387

43.
Journal:	Am J Gastroenterol. 2007 May;102(5):1070-6. Epub 2007 Mar 22.
Title:	Detection of hypermethylated DNA or cyclooxygenase-2 messenger RNA in fecal samples of patients with colorectal cancer or polyps.
Author:	Leung, Wai K\|To, Ka-Fai\|Man, Ellen P S\|Chan, Michael W Y\|Hui, Aric J\|Ng, Simon S M\|Lau, James Y W\|Sung, Joseph J Y
PMID:	17378912

44.
Journal:	Carcinogenesis. 2007 Oct;28(10):2207-17.
Title:	Aspirin blocks proliferation in colon cells by inducing a G1 arrest and apoptosis through activation of the checkpoint kinase ATM.
Author:	Luciani, M Gloria\|Campregher, Christoph\|Gasche, Christoph
PMID:	17510082

45.
Journal:	Cancer Res. 2007 Dec 1;67(23):11158-65.
Title:	Novel NBS1 heterozygous germ line mutation causing MRE11-binding domain loss predisposes to common types of cancer.
Author:	Ebi, Hiromichi\|Matsuo, Keitaro\|Sugito, Nobuyoshi\|Suzuki, Motoshi\|Osada, Hirotaka\|Tajima, Kazuo\|Ueda, Ryuzo\|Takahashi, Takashi
PMID:	18056440

46.
Journal:	Oncogene. 2008 Feb 7;27(7):1013-8. Epub 2007 Aug 13.
Title:	Atm is a negative regulator of intestinal neoplasia.
Author:	Kwong, L N\|Weiss, K R\|Haigis, K M\|Dove, W F
PMID:	17700532

47.
Journal:	Carcinogenesis. 2008 Jan;29(1):139-46.
Title:	Chemopreventive properties of pinoresinol-rich olive oil involve a selective activation of the ATM-p53 cascade in colon cancer cell lines.
Author:	Fini, Lucia\|Hotchkiss, Erin\|Fogliano, Vincenzo\|Graziani, Giulia\|Romano, Marco\|De Vol, Edward B\|Qin, Huanying\|Selgrad, Michael\|Boland, C Richard\|Ricciardiello, Luigi
PMID:	17999988

48.
Journal:	DNA Repair (Amst). 2008 Feb 1;7(2):239-52.
Title:	Hypersensitivity to chromium-induced DNA damage correlates with constitutive deregulation of upstream p53 kinases in p21-/- HCT116 colon cancer cells.
Author:	Hill, Richard\|Leidal, Andrew M\|Madureira, Patricia A\|Gillis, Laura D\|Cochrane, Haley K\|Waisman, David M\|Chiu, Arthur\|Lee, Patrick W K
PMID:	18024214

49.
Journal:	Br J Nutr. 2008 Jul;100(1):27-35.
Title:	Response of cell cycle/stress-related protein expression and DNA damage upon treatment of CaCo2 cells with anthocyanins.
Author:	Renis, Marcella\|Calandra, Laura\|Scifo, Christian\|Tomasello, Barbara\|Cardile, Venera\|Vanella, Luca\|Bei, Roberto\|La Fauci, Luca\|Galvano, Fabio
PMID:	18053307

50.
Journal:	J Clin Invest. 2008 Jan;118(1):79-88.
Title:	Targeting lysosomal degradation induces p53-dependent cell death and prevents cancer in mouse models of lymphomagenesis.
Author:	Maclean, Kirsteen H\|Dorsey, Frank C\|Cleveland, John L\|Kastan, Michael B
PMID:	18097482

51.
Journal:	Oncogene. 2008 Jun 5;27(25):3615-23.
Title:	p21(WAF1/CIP1) induction by 5-azacytosine nucleosides requires DNA damage.
Author:	Jiemjit, A\|Fandy, T E\|Carraway, H\|Bailey, K A\|Baylin, S\|Herman, J G\|Gore, S D
PMID:	18223691

52.
Journal:	Clin Cancer Res. 2008 Mar 15;14(6):1877-87.
Title:	Ataxia telangiectasia mutated and p21CIP1 modulate cell survival of drug-induced senescent tumor cells: implications for chemotherapy.
Author:	Crescenzi, Elvira\|Palumbo, Giuseppe\|de Boer, Jasper\|Brady, Hugh J M
PMID:	18347191

53.
Journal:	Mol Pharmacol. 2008 Jul;74(1):173-83.
Title:	AKT is activated in an ataxia-telangiectasia and Rad3-related-dependent manner in response to temozolomide and confers protection against drug-induced cell growth inhibition.
Author:	Caporali, Simona\|Levati, Lauretta\|Starace, Giuseppe\|Ragone, Gianluca\|Bonmassar, Enzo\|Alvino, Ester\|D'Atri, Stefania
PMID:	18413665

54.
Journal:	Anticancer Res. 2008 Mar-Apr;28(2A):583-92.
Title:	Cellular response to irinotecan in colon cancer cell lines showing differential response to 5-fluorouracil.
Author:	Haug, Kristiane\|Kravik, K Liza\|De Angelis, Paula M
PMID:	18506996

55.
Journal:	Ann Oncol. 2008 Nov;19(11):1875-81.
Title:	Telomere shortening is correlated with the DNA damage response and telomeric protein down-regulation in colorectal preneoplastic lesions.
Author:	Raynaud, C M\|Jang, S J\|Nuciforo, P\|Lantuejoul, S\|Brambilla, E\|Mounier, N\|Olaussen, K A\|Andre, F\|Morat, L\|Sabatier, L\|Soria, J-C
PMID:	18641004

56.
Journal:	Mutat Res. 2008 Oct 14;645(1-2):27-32.
Title:	Colorectal cancers in patients with the (9A/6A) polymorphism of TGFBR1 exhibit lesser inter-(simple sequence repeat) PCR genomic instability and present clinically at greater age.
Author:	Dutt, Smitha S\|Chen, Neng\|Darbary, Huferesh K\|Swede, Helen\|Petrelli, Nicholas J\|Stoler, Daniel L\|Anderson, Garth R
PMID:	18778720

57.
Journal:	Cancer Biol Ther. 2008 Nov;7(11):1783-6. Epub 2008 Nov 4.
Title:	Deficiency of Bloom syndrome helicase activity is radiomimetic.
Author:	Horowitz, David P\|Topaloglu, Ozlem\|Zhang, Yonggang\|Bunz, Fred
PMID:	18787401

58.
Journal:	Biochem Biophys Res Commun. 2008 Nov 21;376(3):509-13.
Title:	Characterization of a cancer cell line that expresses a splicing variant form of 53BP1: separation of checkpoint and repair functions in 53BP1.
Author:	Iwabuchi, Kuniyoshi\|Matsui, Tadashi\|Hashimoto, Mitsumasa\|Matsumoto, Yoshihisa\|Kurihara, Takayuki\|Date, Takayasu
PMID:	18804090

59.
Journal:	Chem Biol Interact. 2009 Jan 27;177(2):121-7.
Title:	Kaempferol induces apoptosis in human HCT116 colon cancer cells via the Ataxia-Telangiectasia Mutated-p53 pathway with the involvement of p53 Upregulated Modulator of Apoptosis.
Author:	Li, Wei\|Du, Bingna\|Wang, Tianyi\|Wang, Siling\|Zhang, Jinghai
PMID:	19028473

60.
Journal:	Int J Cancer. 2009 Jun 15;124(12):2797-803.
Title:	Ascochlorin activates p53 in a manner distinct from DNA damaging agents.
Author:	Jeong, Ji-Hak\|Nakajima, Hiroo\|Magae, Junji\|Furukawa, Chiharu\|Taki, Keiko\|Otsuka, Kensuke\|Tomita, Masanori\|Lee, In-Seon\|Kim, Cheorl-Ho\|Chang, Hyeun-Wook\|Min, Kwan-Sik\|Park, Kwang-Kyun\|Park, Kwan-Kyu\|Chang, Young-Chae
PMID:	19253369

61.
Journal:	Br J Cancer. 2009 Jul 21;101(2):357-62.
Title:	Explorative study to identify novel candidate genes related to oxaliplatin efficacy and toxicity using a DNA repair array.
Author:	Kweekel, D M\|Antonini, N F\|Nortier, J W R\|Punt, C J A\|Gelderblom, H\|Guchelaar, H-J
PMID:	19536092

62.
Journal:	Cell Cycle. 2009 Oct 1;8(19):3157-64. Epub 2009 Oct 3.
Title:	Hypoxia-mediated regulation of Cdc25A phosphatase by p21 and miR-21.
Author:	de Oliveira, Pierre E Queiroz\|Zhang, Lin\|Wang, Zhenghe\|Lazo, John S
PMID:	19738433

63.
Journal:	Neoplasia. 2009 Nov;11(11):1226-34.
Title:	Naphthalimides induce G(2) arrest through the ATM-activated Chk2-executed pathway in HCT116 cells.
Author:	Zhu, Hong\|Miao, Ze-Hong\|Huang, Min\|Feng, Jian-Ming\|Zhang, Zhi-Xiang\|Lu, Jin-Jian\|Cai, Yu-Jun\|Tong, Lin-Jiang\|Xu, Yu-Fang\|Qian, Xu-Hong\|Ding, Jian
PMID:	19881958

64.
Journal:	Eur J Cancer. 2010 Dec;46(18):3365-74.
Title:	Molecular targets of apigenin in colorectal cancer cells: involvement of p21, NAG-1 and p53.
Author:	Zhong, Yi\|Krisanapun, Chutwadee\|Lee, Seong-Ho\|Nualsanit, Thararat\|Sams, Carl\|Peungvicha, Penchom\|Baek, Seung Joon
PMID:	20709524

65.
Journal:	J Biol Chem. 2010 Oct 22;285(43):33010-7.
Title:	Selenium compounds activate ATM-dependent DNA damage response via the mismatch repair protein hMLH1 in colorectal cancer cells.
Author:	Qi, Yongmei\|Schoene, Norberta W\|Lartey, Frederick M\|Cheng, Wen-Hsing
PMID:	20709753

66.
Journal:	Radiat Oncol. 2010 Nov 15;5:107.
Title:	Cell death by the quinoxaline dioxide DCQ in human colon cancer cells is enhanced under hypoxia and is independent of p53 and p21.
Author:	El-Khatib, Mona\|Geara, Fady\|Haddadin, Makhluf J\|Gali-Muhtasib, Hala
PMID:	21078189

67.
Journal:	Genes Cancer. 2010 Sep;1(9):917-26.
Title:	The "Mutated in Colorectal Cancer" Protein Is a Novel Target of the UV-Induced DNA Damage Checkpoint.
Author:	Pangon, Laurent\|Sigglekow, Nicholas D\|Larance, Mark\|Al-Sohaily, Sam\|Mladenova, Dessislava N\|Selinger, Christina I\|Musgrove, Elizabeth A\|Kohonen-Corish, Maija R J
PMID:	21779472

68.
Journal:	BMC Cancer. 2011 Feb 21;11:79.
Title:	A p53-independent role for the MDM2 antagonist Nutlin-3 in DNA damage response initiation.
Author:	Valentine, Jane M\|Kumar, Sonia\|Moumen, Abdeladim
PMID:	21338495

69.
Journal:	Cell Death Dis. 2011 Mar 10;2:e128.
Title:	Phosphorylation of SMC1 by ATR is required for desferrioxamine (DFO)-induced apoptosis.
Author:	So, E Y\|Ausman, M\|Saeki, T\|Ouchi, T
PMID:	21390062

70.
Journal:	Mol Cell Biochem. 2011 Aug;354(1-2):247-52.
Title:	Curcumin induces DNA damage and caffeine-insensitive cell cycle arrest in colorectal carcinoma HCT116 cells.
Author:	Lu, Jin-Jian\|Cai, Yu-Jun\|Ding, Jian
PMID:	21526346

71.
Journal:	Int J Oncol. 2011 Aug;39(2):393-400.
Title:	Priming and potentiation of DNA damage response by fibronectin in human colon cancer cells and tumor-derived myofibroblasts.
Author:	De Wever, Olivier\|Sobczak-Thepot, Joelle\|Vercoutter-Edouart, Anne-Sophie\|Michalski, Jean-Claude\|Ouelaa-Benslama, Radia\|Stupack, Dwayne G\|Bracke, Marc\|Wang, Jean Y J\|Gespach, Christian\|Emami, Shahin
PMID:	21567080

72.
Journal:	Toxicol Appl Pharmacol. 2011 Aug 1;254(3):288-98.
Title:	5-Methoxyflavanone induces cell cycle arrest at the G2/M phase, apoptosis and autophagy in HCT116 human colon cancer cells.
Author:	Shin, Soon Young\|Hyun, Jiye\|Yu, Jae-Ran\|Lim, Yoongho\|Lee, Young Han
PMID:	21616090

73.
Journal:	Mol Cell Biochem. 2011 Nov;357(1-2):255-62.
Title:	Dual role of insulin-like growth factor-1 in acetyl-CoA carboxylase-alpha activity in human colon cancer cells HCT-8: downregulating its expression and phosphorylation.
Author:	Luo, Di-Xian\|Peng, Xu-hong\|Xiong, Yan\|Liao, Duan-Fang\|Cao, Deliang\|Li, Longjiang
PMID:	21638027

74.
Journal:	Int J Oncol. 2011 Sep;39(3):673-82.
Title:	DNA damage signaling in response to 5-fluorouracil in three colorectal cancer cell lines with different mismatch repair and TP53 status.
Author:	Adamsen, Birgitte L\|Kravik, Katherine L\|De Angelis, Paula M
PMID:	21674128

75.
Journal:	Radiother Oncol. 2011 Jun;99(3):293-9.
Title:	AMPK regulates metabolism and survival in response to ionizing radiation.
Author:	Zannella, Vanessa E\|Cojocari, Dan\|Hilgendorf, Susan\|Vellanki, Ravi N\|Chung, Stephen\|Wouters, Bradly G\|Koritzinsky, Marianne
PMID:	21715037

76.
Journal:	Cancer Res. 2011 Sep 1;71(17):5904-14.
Title:	Blocking Hedgehog survival signaling at the level of the GLI genes induces DNA damage and extensive cell death in human colon carcinoma cells.
Author:	Mazumdar, Tapati\|Devecchio, Jennifer\|Agyeman, Akwasi\|Shi, Ting\|Houghton, Janet A
PMID:	21747117

77.
Journal:	Oncotarget. 2011 Aug;2(8):638-45.
Title:	The GLI genes as the molecular switch in disrupting Hedgehog signaling in colon cancer.
Author:	Mazumdar, Tapati\|DeVecchio, Jennifer\|Agyeman, Akwasi\|Shi, Ting\|Houghton, Janet A
PMID:	21860067

78.
Journal:	PLoS One. 2011;6(10):e24429.
Title:	Cellular stress induced alterations in microRNA let-7a and let-7b expression are dependent on p53.
Author:	Saleh, Anthony D\|Savage, Jason E\|Cao, Liu\|Soule, Benjamin P\|Ly, David\|DeGraff, William\|Harris, Curtis C\|Mitchell, James B\|Simone, Nicole L
PMID:	22022355

79.
Journal:	PLoS One. 2011;6(12):e28862.
Title:	Checkpoint signaling, base excision repair, and PARP promote survival of colon cancer cells treated with 5-fluorodeoxyuridine but not 5-fluorouracil.
Author:	Geng, Liyi\|Huehls, Amelia M\|Wagner, Jill M\|Huntoon, Catherine J\|Karnitz, Larry M
PMID:	22194930

80.
Journal:	Exp Ther Med. 2011 May;2(3):393-397.
Title:	Trifluorothymidine exhibits potent antitumor activity via the induction of DNA double-strand breaks.
Author:	Suzuki, Norihiko\|Nakagawa, Fumio\|Nukatsuka, Mamoru\|Fukushima, Masakazu
PMID:	22977515

81.
Journal:	DNA Cell Biol. 2012 Jan;31(1):15-29.
Title:	Cooperative enhancement of radiosensitivity after combined treatment of 17-(allylamino)-17-demethoxygeldanamycin and celecoxib in human lung and colon cancer cell lines.
Author:	Kim, Young-Mee\|Pyo, Hongryull
PMID:	21830942

82.
Journal:	Cell Signal. 2012 Jan;24(1):316-24.
Title:	The p53-p21WAF1 checkpoint pathway plays a protective role in preventing DNA rereplication induced by abrogation of FOXF1 function.
Author:	Lo, Pang-Kuo\|Lee, Ji Shin\|Sukumar, Saraswati
PMID:	21964066

83.
Journal:	Radiother Oncol. 2012 Sep;104(3):395-400.
Title:	Combination of quercetin with radiotherapy enhances tumor radiosensitivity in vitro and in vivo.
Author:	Lin, Chenghe\|Yu, Yan\|Zhao, Hong-Guan\|Yang, Aimin\|Yan, Hong\|Cui, Yali
PMID:	22119371

84.
Journal:	Cell Signal. 2012 Jul;24(7):1369-74.
Title:	Down-regulation of Fer induces ROS levels accompanied by ATM and p53 activation in colon carcinoma cells.
Author:	Makovski, Adar\|Yaffe, Etai\|Shpungin, Sally\|Nir, Uri
PMID:	22434045

85.
Journal:	Evid Based Complement Alternat Med. 2012;2012:178178.
Title:	Activations of Both Extrinsic and Intrinsic Pathways in HCT 116 Human Colorectal Cancer Cells Contribute to Apoptosis through p53-Mediated ATM/Fas Signaling by Emilia sonchifolia Extract, a Folklore Medicinal Plant.
Author:	Lan, Yu-Hsuan\|Chiang, Jo-Hua\|Huang, Wen-Wen\|Lu, Chi-Cheng\|Chung, Jing-Gung\|Wu, Tian-Shung\|Jhan, Jia-Hua\|Lin, Kuei-Li\|Pai, Shu-Jen\|Chiu, Yu-Jen\|Tsuzuki, Minoru\|Yang, Jai-Sing
PMID:	22474491

86.
Journal:	Int J Oncol. 2012 Jul;41(1):76-82.
Title:	Bortezomib induces G2-M arrest in human colon cancer cells through ROS-inducible phosphorylation of ATM-CHK1.
Author:	Hong, Yong Sang\|Hong, Seung-Woo\|Kim, Seung-Mi\|Jin, Dong-Hoon\|Shin, Jae-Sik\|Yoon, Dok Hyun\|Kim, Kyu-Pyo\|Lee, Jae-Lyun\|Heo, Dae Seog\|Lee, Jung Shin\|Kim, Tae Won
PMID:	22552540

87.
Journal:	Undersea Hyperb Med. 2012 May-Jun;39(3):693-8.
Title:	Hyperbaric oxygen therapy reduces COX-2 expression in a dimethylhydrazine-induced rat model of colorectal carcinogenesis.
Author:	Gois, Emanuel Jr\|Daniel, Rosemary A F\|Parra, Rogerio S\|Almeida, Ana L N R\|Rocha, Jose J R\|Garcia, Sergio B\|Feres, Omar
PMID:	22670549

88.
Journal:	Nature. 2012 Aug 30;488(7413):660-4.
Title:	Recurrent R-spondin fusions in colon cancer.
Author:	Seshagiri, Somasekar\|Stawiski, Eric W\|Durinck, Steffen\|Modrusan, Zora\|Storm, Elaine E\|Conboy, Caitlin B\|Chaudhuri, Subhra\|Guan, Yinghui\|Janakiraman, Vasantharajan\|Jaiswal, Bijay S\|Guillory, Joseph\|Ha, Connie\|Dijkgraaf, Gerrit J P\|Stinson, Jeremy\|Gnad, Flo
PMID:	22895193

89.
Journal:	Oncotarget. 2012 Aug;3(8):854-68.
Title:	Regulation of DNA damage following termination of Hedgehog (HH) survival signaling at the level of the GLI genes in human colon cancer.
Author:	Agyeman, Akwasi\|Mazumdar, Tapati\|Houghton, Janet A
PMID:	23097684

90.
Journal:	Oncotarget. 2012 Nov;3(11):1348-55.
Title:	Loss of expression of the double strand break repair protein ATM is associated with worse prognosis in colorectal cancer and loss of Ku70 expression is associated with CIN.
Author:	Beggs, Andrew D\|Domingo, Enric\|McGregor, Megan\|Presz, Mikael\|Johnstone, Elaine\|Midgley, Rachel\|Kerr, David\|Oukrif, Dahmane\|Novelli, Marco\|Abulafi, Muti\|Hodgson, Shirley V\|Fadhil, Wakkas\|Ilyas, Mohammad\|Tomlinson, Ian P M
PMID:	23154512

91.
Journal:	Arq Gastroenterol. 2012 Dec;49(4):273-8.
Title:	CHEK2 1100DELC germline mutation: a frequency study in hereditary breast and colon cancer Brazilian families.
Author:	Abud, Jamile\|Koehler-Santos, Patricia\|Ashton-Prolla, Patricia\|Prolla, Joao Carlos
PMID:	23329222

92.
Journal:	Springerplus. 2012 Dec;1(1):65.
Title:	Inhibition of cancer cell proliferation by 5-fluoro-2'-deoxycytidine, a DNA methylation inhibitor, through activation of DNA damage response pathway.
Author:	Zhao, Quanyi\|Fan, Jiadong\|Hong, Wei\|Li, Lianyun\|Wu, Min
PMID:	23397046

93.
Journal:	J Pathol. 2013 Apr;229(5):697-704.
Title:	Whole-genome methylation analysis of benign and malignant colorectal tumours.
Author:	Beggs, Andrew D\|Jones, Angela\|El-Bahrawy, Mona\|Abulafi, Muti\|Hodgson, Shirley V\|Tomlinson, Ian P M
PMID:	23096130

94.
Journal:	Eur J Cancer. 2013 Mar;49(5):1142-51.
Title:	The impairment of the High Mobility Group A (HMGA) protein function contributes to the anticancer activity of trabectedin.
Author:	D'Angelo, Daniela\|Borbone, Eleonora\|Palmieri, Dario\|Uboldi, Sarah\|Esposito, Francesco\|Frapolli, Roberta\|Pacelli, Roberto\|D'Incalci, Maurizio\|Fusco, Alfredo
PMID:	23149213

95.
Journal:	Mol Med Rep. 2013 Feb;7(2):559-64.
Title:	MicroRNA-18a upregulates autophagy and ataxia telangiectasia mutated gene expression in HCT116 colon cancer cells.
Author:	Qased, Abu Baker\|Yi, Heqing\|Liang, Nan\|Ma, Shumei\|Qiao, Shixing\|Liu, Xiaodong
PMID:	23229340

96.
Journal:	PLoS One. 2013;8(2):e57036.
Title:	MicroRNA-18a attenuates DNA damage repair through suppressing the expression of ataxia telangiectasia mutated in colorectal cancer.
Author:	Wu, Chung-Wah\|Dong, Yu-Juan\|Liang, Qiao-Yi\|He, Xin-Qi\|Ng, Simon S M\|Chan, Francis K L\|Sung, Joseph J Y\|Yu, Jun
PMID:	23437304

97.
Journal:	Int J Oncol. 2013 Jul;43(1):289-96.
Title:	Genistein induces G2/M cell cycle arrest and apoptosis via ATM/p53-dependent pathway in human colon cancer cells.
Author:	Zhang, Zhiyu\|Wang, Chong-Zhi\|Du, Guang-Jian\|Qi, Lian-Wen\|Calway, Tyler\|He, Tong-Chuan\|Du, Wei\|Yuan, Chun-Su
PMID:	23686257

98.
Journal:	Free Radic Res. 2013 Sep;47(9):672-82.
Title:	Cytotoxicity of 1,4-diamino-2-butanone, a putrescine analogue, to RKO cells: mechanism and redox imbalance.
Author:	Soares, C O\|Boiani, M\|Marnett, L J\|Bechara, E J H
PMID:	23758064

99.
Journal:	J Proteome Res. 2013 Sep 6;12(9):4136-51.
Title:	TIMP-1 increases expression and phosphorylation of proteins associated with drug resistance in breast cancer cells.
Author:	Hekmat, Omid\|Munk, Stephanie\|Fogh, Louise\|Yadav, Rachita\|Francavilla, Chiara\|Horn, Heiko\|Wurtz, Sidse Ornbjerg\|Schrohl, Anne-Sofie\|Damsgaard, Britt\|Romer, Maria Unni\|Belling, Kirstine C\|Jensen, Niels Frank\|Gromova, Irina\|Bekker-Jensen, Dorte B\|Moreira, Jo
PMID:	23909892

100.
Journal:	J Exp Med. 2013 Nov 18;210(12):2675-92.
Title:	Modulation of NKG2D ligand expression and metastasis in tumors by spironolactone via RXRgamma activation.
Author:	Leung, Wai-Hang\|Vong, Queenie P\|Lin, Wenwei\|Janke, Laura\|Chen, Taosheng\|Leung, Wing
PMID:	24190430

101.
Journal:	PLoS One. 2013 Nov 19;8(11):e81034.
Title:	Telomere-binding protein TPP1 modulates telomere homeostasis and confers radioresistance to human colorectal cancer cells.
Author:	Yang, Lei\|Wang, Wenbo\|Hu, Liu\|Yang, Xiaoxi\|Zhong, Juan\|Li, Zheng\|Yang, Hui\|Lei, Han\|Yu, Haijun\|Liao, ZhengKai\|Zhou, Fuxiang\|Xie, Conghua\|Zhou, Yunfeng
PMID:	24260532

102.
Journal:	Mol Oncol. 2014 Feb;8(1):83-92.
Title:	miR-203 induces oxaliplatin resistance in colorectal cancer cells by negatively regulating ATM kinase.
Author:	Zhou, Yunfei\|Wan, Guohui\|Spizzo, Riccardo\|Ivan, Cristina\|Mathur, Rohit\|Hu, Xiaoxiao\|Ye, Xiangcang\|Lu, Jia\|Fan, Fan\|Xia, Ling\|Calin, George A\|Ellis, Lee M\|Lu, Xiongbin
PMID:	24145123

103.
Journal:	Clin Cancer Res. 2014 Feb 15;20(4):1042-52.
Title:	Overexpression of the circadian clock gene Bmal1 increases sensitivity to oxaliplatin in colorectal cancer.
Author:	Zeng, Zhao-lei\|Luo, Hui-yan\|Yang, Jing\|Wu, Wen-jing\|Chen, Dong-liang\|Huang, Peng\|Xu, Rui-hua
PMID:	24277452

104.
Journal:	Biochem Pharmacol. 2014 Aug 1;90(3):265-75.
Title:	Autophagy inhibition switches low-dose camptothecin-induced premature senescence to apoptosis in human colorectal cancer cells.
Author:	Zhang, Jian-wei\|Zhang, Shan-shan\|Song, Jian-rui\|Sun, Kai\|Zong, Chen\|Zhao, Qiu-dong\|Liu, Wen-ting\|Li, Rong\|Wu, Meng-chao\|Wei, Li-xin
PMID:	24858802

105.
Journal:	J Exp Clin Cancer Res. 2014 Aug 5;33:65.
Title:	Promoter methylation of tumor suppressor genes in pre-neoplastic lesions; potential marker of disease recurrence.
Author:	Rengucci, Claudia\|De Maio, Giulia\|Casadei Gardini, Andrea\|Zucca, Mattia\|Scarpi, Emanuela\|Zingaretti, Chiara\|Foschi, Giovanni\|Tumedei, Maria Maddalena\|Molinari, Chiara\|Saragoni, Luca\|Puccetti, Maurizio\|Amadori, Dino\|Zoli, Wainer\|Calistri, Daniele
PMID:	25091577

106.
Journal:	Onco Targets Ther. 2014 Oct 24;7:1955-61.
Title:	Downregulated Ku70 and ATM associated to poor prognosis in colorectal cancer among Chinese patients.
Author:	Lu, Yuanfang\|Gao, Jingyan\|Lu, Yuanming
PMID:	25368522

107.
Journal:	BMC Cancer. 2014 Nov 20;14:851.
Title:	High mobility group A1 protein expression reduces the sensitivity of colon and thyroid cancer cells to antineoplastic drugs.
Author:	D'Angelo, Daniela\|Mussnich, Paula\|Rosa, Roberta\|Bianco, Roberto\|Tortora, Giampaolo\|Fusco, Alfredo
PMID:	25409711

108.
Journal:	Cancer Biol Ther. 2014;15(12):1700-4.
Title:	Distinct DNA damage determines differential phosphorylation of Chk2.
Author:	Ouchi, Mutsuko\|Ouchi, Toru
PMID:	25535901

109.
Journal:	Int J Oncol. 2015 Jan;46(1):63-70.
Title:	5FU resistance abrogates the amplified cytotoxic effects induced by inhibiting checkpoint kinase 1 in p53mutated colon cancer cells.
Author:	Akasaka, Tomofumi\|Tsujii, Masahiko\|Kondo, Jumpei\|Hayashi, Yoshito\|Ying, Jin\|Lu, Yuquan\|Kato, Motohiko\|Yamada, Takuya\|Yamamoto, Shunsuke\|Inoue, Takuya\|Tsujii, Yoshiki\|Maekawa, Akira\|Fujinaga, Tetsuji\|Shiraishi, Eri\|Hiyama, Satoshi\|Inoue, Takahiro\|Shinzaki,
PMID:	25310623

110.
Journal:	Cancer Med. 2015 Feb;4(2):278-92.
Title:	Zerumbone increases oxidative stress in a thiol-dependent ROS-independent manner to increase DNA damage and sensitize colorectal cancer cells to radiation.
Author:	Deorukhkar, Amit\|Ahuja, Niharika\|Mercado, Armando-Lopez\|Diagaradjane, Parmeswaran\|Raju, Uma\|Patel, Nalini\|Mohindra, Pranshu\|Diep, Nga\|Guha, Sushovan\|Krishnan, Sunil
PMID:	25450478

111.
Journal:	Gastroenterology. 2015 Mar;148(3):556-64.
Title:	Prevalence of germline mutations in cancer predisposition genes in patients with pancreatic cancer.
Author:	Grant, Robert C\|Selander, Iris\|Connor, Ashton A\|Selvarajah, Shamini\|Borgida, Ayelet\|Briollais, Laurent\|Petersen, Gloria M\|Lerner-Ellis, Jordan\|Holter, Spring\|Gallinger, Steven
PMID:	25479140

112.
Journal:	Cancer Lett. 2015 Feb 28;357(2):582-90.
Title:	Dual phosphoinositide 3-kinase/mammalian target of rapamycin inhibitor is an effective radiosensitizer for colorectal cancer.
Author:	Chen, Yu-Hsuan\|Wei, Ming-Feng\|Wang, Chun-Wei\|Lee, Hsiao-Wei\|Pan, Shiow-Lin\|Gao, Ming\|Kuo, Sung-Hsin\|Cheng, Ann-Lii\|Teng, Che-Ming
PMID:	25497009

113.
Journal:	Mol Cancer Ther. 2015 Feb;14(2):597-607.
Title:	Targeting BRG1 chromatin remodeler via its bromodomain for enhanced tumor cell radiosensitivity in vitro and in vivo.
Author:	Kwon, Su-Jung\|Lee, Seul-Ki\|Na, Juri\|Lee, Shin-Ai\|Lee, Han-Sae\|Park, Ji-Hye\|Chung, June-Key\|Youn, Hyewon\|Kwon, Jongbum
PMID:	25504753

114.
Journal:	Br J Cancer. 2015 Mar 3;112(5):851-6.
Title:	Tailoring heated intraperitoneal mitomycin C for peritoneal metastases originating from colorectal carcinoma: a translational approach to improve survival.
Author:	Kwakman, R\|de Cuba, E M V\|de Winter, J P\|de Hingh, I H J T\|Delis-van Diemen, P M\|Tijssen, M\|Rooimans, M A\|Krijgsman, O\|Carvalho, B\|Peters, G J\|Bonjer, H J\|Meijer, G A\|Te Velde, E A
PMID:	25668003

115.
Journal:	Cancer Genet. 2015 Jan-Feb;208(1-2):35-40.
Title:	Systematic search for rare variants in Finnish early-onset colorectal cancer patients.
Author:	Tanskanen, Tomas\|Gylfe, Alexandra E\|Katainen, Riku\|Taipale, Minna\|Renkonen-Sinisalo, Laura\|Jarvinen, Heikki\|Mecklin, Jukka-Pekka\|Bohm, Jan\|Kilpivaara, Outi\|Pitkanen, Esa\|Palin, Kimmo\|Vahteristo, Pia\|Tuupanen, Sari\|Aaltonen, Lauri A
PMID:	25749350

116.
Journal:	J Mol Cell Biol. 2015 Apr;7(2):105-18.
Title:	P53 deficiency-induced Smad1 upregulation suppresses tumorigenesis and causes chemoresistance in colorectal cancers.
Author:	Ruan, Xinsen\|Zuo, Qiao\|Jia, Hao\|Chau, Jenny\|Lin, Jinlin\|Ao, Junping\|Xia, Xuechun\|Liu, Huijuan\|Habib, Samy L\|Fu, Chuangang\|Li, Baojie
PMID:	25757624

117.
Journal:	Toxicol In Vitro. 2015 Aug;29(5):1156-65.
Title:	Resveratrol induces DNA damage in colon cancer cells by poisoning topoisomerase II and activates the ATM kinase to trigger p53-dependent apoptosis.
Author:	Demoulin, Benjamin\|Hermant, Maryse\|Castrogiovanni, Cedric\|Staudt, Catherine\|Dumont, Patrick
PMID:	25952326

118.
Journal:	Nat Genet. 2015 Aug;47(8):906-10.
Title:	Loss-of-function variants in ATM confer risk of gastric cancer.
Author:	Helgason, Hannes\|Rafnar, Thorunn\|Olafsdottir, Halla S\|Jonasson, Jon G\|Sigurdsson, Asgeir\|Stacey, Simon N\|Jonasdottir, Adalbjorg\|Tryggvadottir, Laufey\|Alexiusdottir, Kristin\|Haraldsson, Asgeir\|le Roux, Louise\|Gudmundsson, Julius\|Johannsdottir, Hrefna\|Oddss
PMID:	26098866

119.
Journal:	Front Pharmacol. 2015 Jul 22;6:147.
Title:	Simultaneous inhibition of ATR and PARP sensitizes colon cancer cell lines to irinotecan.
Author:	Abu-Sanad, Atlal\|Wang, Yunzhe\|Hasheminasab, Fatemeh\|Panasci, Justin\|Noe, Alycia\|Rosca, Lorena\|Davidson, David\|Amrein, Lilian\|Sharif-Askari, Bahram\|Aloyz, Raquel\|Panasci, Lawrence
PMID:	26257651

120.
Journal:	Cancer Biol Ther. 2015;16(12):1738-45.
Title:	Special AT-rich sequence binding protein 1 expression correlates with response to preoperative radiotherapy and clinical outcome in rectal cancer.
Author:	Meng, Wen-Jian\|Pathak, Surajit\|Ding, Zhen-Yu\|Zhang, Hong\|Adell, Gunnar\|Holmlund, Birgitta\|Li, Yuan\|Zhou, Zong-Guang\|Sun, Xiao-Feng
PMID:	26528635

121.
Journal:	J Nat Prod. 2015 Dec 24;78(12):2983-93.
Title:	Antitumor Activity of Americanin A Isolated from the Seeds of Phytolacca americana by Regulating the ATM/ATR Signaling Pathway and the Skp2-p27 Axis in Human Colon Cancer Cells.
Author:	Jung, Cholomi\|Hong, Ji-Young\|Bae, Song Yi\|Kang, Sam Sik\|Park, Hyen Joo\|Lee, Sang Kook
PMID:	26595875

122.
Journal:	Tumour Biol. 2016 May;37(5):6389-402.
Title:	Cooperative effect of BI-69A11 and celecoxib enhances radiosensitization by modulating DNA damage repair in colon carcinoma.
Author:	Pal, Ipsita\|Dey, Kaushik Kumar\|Chaurasia, Madhuri\|Parida, Sheetal\|Das, Subhayan\|Rajesh, Y\|Sharma, Kulbhushan\|Chowdhury, Tamohan\|Mandal, Mahitosh
PMID:	26631035

123.
Journal:	Cancer Genet. 2016 Mar;209(3):70-4.
Title:	The risk for developing cancer in Israeli ATM, BLM, and FANCC heterozygous mutation carriers.
Author:	Laitman, Yael\|Boker-Keinan, Lital\|Berkenstadt, Michal\|Liphsitz, Irena\|Weissglas-Volkov, Daphna\|Ries-Levavi, Liat\|Sarouk, Ifat\|Pras, Elon\|Friedman, Eitan
PMID:	26778106

124.
Journal:	PLoS One. 2016 Jan 19;11(1):e0147053.
Title:	Dynamic Effects of Topoisomerase I Inhibition on R-Loops and Short Transcripts at Active Promoters.
Author:	Marinello, Jessica\|Bertoncini, Stefania\|Aloisi, Iris\|Cristini, Agnese\|Malagoli Tagliazucchi, Guidantonio\|Forcato, Mattia\|Sordet, Olivier\|Capranico, Giovanni
PMID:	26784695

125.
Journal:	PLoS One. 2016 Apr 20;11(4):e0153818.
Title:	Efficient Activation of Apoptotic Signaling during Mitotic Arrest with AK301.
Author:	Chopra, Avijeet\|Bond, Michael J\|Bleiler, Marina\|Yeagley, Michelle\|Wright, Dennis\|Giardina, Charles
PMID:	27097159

126.
Journal:	Cancer Epidemiol Biomarkers Prev. 2016 Jul;25(7):1185-91.
Title:	Association of Common Susceptibility Variants of Pancreatic Cancer in Higher-Risk Patients: A PACGENE Study.
Author:	Childs, Erica J\|Chaffee, Kari G\|Gallinger, Steven\|Syngal, Sapna\|Schwartz, Ann G\|Cote, Michele L\|Bondy, Melissa L\|Hruban, Ralph H\|Chanock, Stephen J\|Hoover, Robert N\|Fuchs, Charles S\|Rider, David N\|Amundadottir, Laufey T\|Stolzenberg-Solomon, Rachael\|Wolpin
PMID:	27197284

127.
Journal:	Front Chem. 2016 Jun 28;4:28.
Title:	Guardian of the Human Genome: Host Defense Mechanisms against LINE-1 Retrotransposition.
Author:	Ariumi, Yasuo
PMID:	27446907

128.
Journal:	Int J Oncol. 2016 Oct;49(4):1600-8.
Title:	Deficiency of 53BP1 inhibits the radiosensitivity of colorectal cancer.
Author:	Xiao, Yong\|Zheng, Xiumei\|Huang, Ai\|Liu, Tao\|Zhang, Tao\|Ma, Hong
PMID:	27499037

129.
Journal:	Med Oncol. 2016 Oct;33(10):106.
Title:	Targeted molecular profiling of rare genetic alterations in colorectal cancer using next-generation sequencing.
Author:	Jauhri, Mayank\|Bhatnagar, Akanksha\|Gupta, Satish\|Shokeen, Yogender\|Minhas, Sachin\|Aggarwal, Shyam
PMID:	27568332

130.
Journal:	Oncotarget. 2016 Sep 20;7(38):60807-60822.
Title:	Phenotypic consequences of somatic mutations in the ataxia-telangiectasia mutated gene in non-small cell lung cancer.
Author:	Weber, Anika Maria\|Drobnitzky, Neele\|Devery, Aoife Maire\|Bokobza, Sivan Mili\|Adams, Richard A\|Maughan, Timothy S\|Ryan, Anderson Joseph
PMID:	27602502

131.
Journal:	Cancer Biol Ther. 2016 Nov;17(11):1139-1148.
Title:	Chk1 and DNA-PK mediate TPEN-induced DNA damage in a ROS dependent manner in human colon cancer cells.
Author:	Rahal, Omar Nasser\|Fatfat, Maamoun\|Hankache, Carla\|Osman, Bassam\|Khalife, Hala\|Machaca, Khaled\|Muhtasib, Hala-Gali
PMID:	27690730

132.
Journal:	Mol Cancer. 2016 Oct 18;15(1):63.
Title:	Spatio-temporal mutation profiles of case-matched colorectal carcinomas and their metastases reveal unique de novo mutations in metachronous lung metastases by targeted next generation sequencing.
Author:	Kovaleva, Valentina\|Geissler, Anna-Lena\|Lutz, Lisa\|Fritsch, Ralph\|Makowiec, Frank\|Wiesemann, Sebastian\|Hopt, Ulrich T\|Passlick, Bernward\|Werner, Martin\|Lassmann, Silke
PMID:	27756406

133.
Journal:	PLoS One. 2016 Dec 8;11(12):e0167675.
Title:	MRE11 and ATM Expression Levels Predict Rectal Cancer Survival and Their Association with Radiotherapy Response.
Author:	Ho, Vincent\|Chung, Liping\|Revoltar, Maxine\|Lim, Stephanie H\|Tut, Thein-Ga\|Abubakar, Askar\|Henderson, Chris J\|Chua, Wei\|Ng, Weng\|Lee, Mark\|De Souza, Paul\|Morgan, Matthew\|Lee, C Soon\|Shin, Joo-Shik
PMID:	27930716

134.
Journal:	Sichuan Da Xue Xue Bao Yi Xue Ban. 2016 Jul;47(4):451-457.
Title:	[Study on the Effect of Overexpression of miR-18a on Cellular Proliferation and Migration by Targeting ATM in Human Colorectal Cancer Cells].
Author:	Liu, Ming-Jia\|Chen, Li-Hong\|Hu, Kai-Feng\|Yang, Xiao-Long\|Dong, Jing-Ying\|Liu, Ji
PMID:	28591941

135.
Journal:	Mol Oncol. 2016 Dec;10(10):1575-1584.
Title:	Somatic mutation detection using various targeted detection assays in paired samples of circulating tumor DNA, primary tumor and metastases from patients undergoing resection of colorectal liver metastases.
Author:	Beije, Nick\|Helmijr, Jean C\|Weerts, Marjolein J A\|Beaufort, Corine M\|Wiggin, Matthew\|Marziali, Andre\|Verhoef, Cornelis\|Sleijfer, Stefan\|Jansen, Maurice P H M\|Martens, John W M
PMID:	28949453

136.
Journal:	J Gastroenterol. 2017 Mar;52(3):327-340.
Title:	Aberrant BLM cytoplasmic expression associates with DNA damage stress and hypersensitivity to DNA-damaging agents in colorectal cancer.
Author:	Votino, Carolina\|Laudanna, Carmelo\|Parcesepe, Pietro\|Giordano, Guido\|Remo, Andrea\|Manfrin, Erminia\|Pancione, Massimo
PMID:	27169843

137.
Journal:	Oncogene. 2017 Feb 2;36(5):700-713.
Title:	MUC13 protects colorectal cancer cells from death by activating the NF-kappaB pathway and is a potential therapeutic target.
Author:	Sheng, Y H\|He, Y\|Hasnain, S Z\|Wang, R\|Tong, H\|Clarke, D T\|Lourie, R\|Oancea, I\|Wong, K Y\|Lumley, J W\|Florin, T H\|Sutton, P\|Hooper, J D\|McMillan, N A\|McGuckin, M A
PMID:	27399336

138.
Journal:	J Cancer Res Clin Oncol. 2017 Mar;143(3):419-431.
Title:	53BP1 loss induces chemoresistance of colorectal cancer cells to 5-fluorouracil by inhibiting the ATM-CHK2-P53 pathway.
Author:	Yao, Jing\|Huang, Ai\|Zheng, Xiumei\|Liu, Tao\|Lin, Zhenyu\|Zhang, Sheng\|Yang, Qin\|Zhang, Tao\|Ma, Hong
PMID:	27838786

139.
Journal:	JAMA Oncol. 2017 Apr 1;3(4):464-471.
Title:	Prevalence and Spectrum of Germline Cancer Susceptibility Gene Mutations Among Patients With Early-Onset Colorectal Cancer.
Author:	Pearlman, Rachel\|Frankel, Wendy L\|Swanson, Benjamin\|Zhao, Weiqiang\|Yilmaz, Ahmet\|Miller, Kristin\|Bacher, Jason\|Bigley, Christopher\|Nelsen, Lori\|Goodfellow, Paul J\|Goldberg, Richard M\|Paskett, Electra\|Shields, Peter G\|Freudenheim, Jo L\|Stanich, Peter P\|Lat
PMID:	27978560

140.
Journal:	Cancer Lett. 2017 Apr 1;390:48-57.
Title:	The depletion of ATM inhibits colon cancer proliferation and migration via B56gamma2-mediated Chk1/p53/CD44 cascades.
Author:	Liu, Rui\|Tang, Jiajia\|Ding, Chaodong\|Liang, Weicheng\|Zhang, Li\|Chen, Tianke\|Xiong, Yan\|Dai, Xiaowei\|Li, Wenfeng\|Xu, Yunsheng\|Hu, Jin\|Lu, Liting\|Liao, Wanqin\|Lu, Xincheng
PMID:	28093285

141.
Journal:	Oncotarget. 2017 Jan 24;8(4):6579-6588.
Title:	Whole-exome sequencing identified mutational profiles of high-grade colon adenomas.
Author:	Lee, Sung Hak\|Jung, Seung Hyun\|Kim, Tae-Min\|Rhee, Je-Keun\|Park, Hyeon-Chun\|Kim, Min Sung\|Kim, Sung Soo\|An, Chang Hyeok\|Lee, Sug Hyung\|Chung, Yeun-Jun
PMID:	28179590

142.
Journal:	Transl Oncol. 2017 Apr;10(2):190-196.
Title:	ATM-Deficient Colorectal Cancer Cells Are Sensitive to the PARP Inhibitor Olaparib.
Author:	Wang, Chen\|Jette, Nicholas\|Moussienko, Daniel\|Bebb, D Gwyn\|Lees-Miller, Susan P
PMID:	28182994

143.
Journal:	Oncotarget. 2017 Mar 7;8(10):17164-17190.
Title:	ATM mutations and E-cadherin expression define sensitivity to EGFR-targeted therapy in colorectal cancer.
Author:	Geissler, Anna-Lena\|Geissler, Miriam\|Kottmann, Daniel\|Lutz, Lisa\|Fichter, Christiane D\|Fritsch, Ralph\|Weddeling, Britta\|Makowiec, Frank\|Werner, Martin\|Lassmann, Silke
PMID:	28199979

144.
Journal:	J Gastrointest Oncol. 2017 Feb;8(1):164-172.
Title:	Potential actionable targets in appendiceal cancer detected by immunohistochemistry, fluorescent in situ hybridization, and mutational analysis.
Author:	Borazanci, Erkut\|Millis, Sherri Z\|Kimbrough, Jeffery\|Doll, Nancy\|Von Hoff, Daniel\|Ramanathan, Ramesh K
PMID:	28280620

145.
Journal:	Oncotarget. 2017 Jun 27;8(26):42487-42494.
Title:	Local recurrences at the anastomotic area are clonally related to the primary tumor in sporadic colorectal carcinoma.
Author:	Vakiani, Efsevia\|Shah, Ronak H\|Berger, Michael F\|Makohon-Moore, Alvin P\|Reiter, Johannes G\|Ostrovnaya, Irina\|Attiyeh, Marc A\|Cercek, Andrea\|Shia, Jinru\|Iacobuzio-Donahue, Christine A\|Solit, David B\|Weiser, Martin R
PMID:	28476018

146.
Journal:	Cell Death Differ. 2017 Sep;24(9):1632-1644.
Title:	NOX2-dependent ATM kinase activation dictates pro-inflammatory macrophage phenotype and improves effectiveness to radiation therapy.
Author:	Wu, Qiuji\|Allouch, Awatef\|Paoletti, Audrey\|Leteur, Celine\|Mirjolet, Celine\|Martins, Isabelle\|Voisin, Laurent\|Law, Frederic\|Dakhli, Haithem\|Mintet, Elodie\|Thoreau, Maxime\|Muradova, Zeinaf\|Gauthier, Melanie\|Caron, Olivier\|Milliat, Fabien\|Ojcius, David M\|Ros
PMID:	28574504

147.
Journal:	Cancer Cell Int. 2017 Aug 7;17:75.
Title:	Aberrantly methylated-differentially expressed genes and pathways in colorectal cancer.
Author:	Liu, Jingwei\|Li, Hao\|Sun, Liping\|Wang, Zhenning\|Xing, Chengzhong\|Yuan, Yuan
PMID:	28794688

148.
Journal:	Food Chem Toxicol. 2017 Oct;108(Pt A):267-275.
Title:	Methyleugenol and selected oxidative metabolites affect DNA-Damage signalling pathways and induce apoptosis in human colon tumour HT29 cells.
Author:	Groh, Isabel Anna Maria\|Esselen, Melanie
PMID:	28818686

149.
Journal:	Cell Death Dis. 2017 Aug 24;8(8):e3019.
Title:	AKT2 suppresses pro-survival autophagy triggered by DNA double-strand breaks in colorectal cancer cells.
Author:	Seiwert, Nina\|Neitzel, Carina\|Stroh, Svenja\|Frisan, Teresa\|Audebert, Marc\|Toulany, Mahmoud\|Kaina, Bernd\|Fahrer, Jorg
PMID:	28837154

150.
Journal:	Sci Rep. 2017 Sep 19;7(1):11864.
Title:	Oligo-Fucoidan prevents IL-6 and CCL2 production and cooperates with p53 to suppress ATM signaling and tumor progression.
Author:	Chen, Li-Mei\|Liu, Po-Yen\|Chen, Yen-An\|Tseng, Hong-Yu\|Shen, Pei-Chun\|Hwang, Pai-An\|Hsu, Hsin-Ling
PMID:	28928376

151.
Journal:	Hum Genet. 2017 Nov;136(11-12):1431-1444.
Title:	Expanding the spectrum of germline variants in cancer.
Author:	Siraj, Abdul K\|Masoodi, Tariq\|Bu, Rong\|Parvathareddy, Sandeep Kumar\|Al-Badawi, Ismail A\|Al-Sanea, Nasser\|Ashari, Luai H\|Abduljabbar, Alaa\|Alhomoud, Samar\|Al-Sobhi, Saif S\|Tulbah, Asma\|Ajarim, Dahish\|Alzoman, Khalid\|Aljuboury, Muna\|Yousef, Hussam Bin\|Al-Da
PMID:	28975465

152.
Journal:	Mutagenesis. 2017 Oct 17;32(5):533-542.
Title:	MicroRNA-binding site polymorphisms in genes involved in colorectal cancer etiopathogenesis and their impact on disease prognosis.
Author:	Schneiderova, Michaela\|Naccarati, Alessio\|Pardini, Barbara\|Rosa, Fabio\|Gaetano, Cornelia Di\|Jiraskova, Katerina\|Opattova, Alena\|Levy, Miroslav\|Veskrna, Karel\|Veskrnova, Veronika\|Buchler, Tomas\|Landi, Stefano\|Vodicka, Pavel\|Vymetalkova, Veronika
PMID:	29048575

153.
Journal:	Ann Transl Med. 2017 Sep;5(18):381.
Title:	Erratum to epigenetics of colorectal cancer: emerging circulating diagnostic and prognostic biomarkers.
Author:
PMID:	29057241

154.
Journal:	Biomed Res Int. 2017;2017:5718968.
Title:	XRRA1 Targets ATM/CHK1/2-Mediated DNA Repair in Colorectal Cancer.
Author:	Wang, Wenjun\|Guo, Minzhang\|Xia, Xiaojun\|Zhang, Chao\|Zeng, Yuan\|Wu, Sipei
PMID:	29082250

155.
Journal:	Oncotarget. 2017 Sep 6;8(48):84258-84275.
Title:	GPER mediates differential effects of estrogen on colon cancer cell proliferation and migration under normoxic and hypoxic conditions.
Author:	Bustos, Viviana\|Nolan, Aine M\|Nijhuis, Anke\|Harvey, Harry\|Parker, Alexandra\|Poulsom, Richard\|McBryan, Jean\|Thomas, Warren\|Silver, Andrew\|Harvey, Brian J
PMID:	29137421

156.
Journal:	Oncol Lett. 2017 Dec;14(6):7825-7828.
Title:	Expression and clinical significance of ATM and PUMA gene in patients with colorectal cancer.
Author:	Xiong, Hui\|Zhang, Jiangnan
PMID:	29344228

157.
Journal:	Gut. 2018 May;67(5):903-917.
Title:	CHK1-targeted therapy to deplete DNA replication-stressed, p53-deficient, hyperdiploid colorectal cancer stem cells.
Author:	Manic, Gwenola\|Signore, Michele\|Sistigu, Antonella\|Russo, Giorgio\|Corradi, Francesca\|Siteni, Silvia\|Musella, Martina\|Vitale, Sara\|De Angelis, Maria Laura\|Pallocca, Matteo\|Amoreo, Carla Azzurra\|Sperati, Francesca\|Di Franco, Simone\|Barresi, Sabina\|Policicch
PMID:	28389531

158.
Journal:	Cancer. 2018 Mar 1;124(5):1070-1082.
Title:	A mutational comparison of adult and adolescent and young adult (AYA) colon cancer.
Author:	Tricoli, James V\|Boardman, Lisa A\|Patidar, Rajesh\|Sindiri, Sivasish\|Jang, Jin S\|Walsh, William D\|McGregor, Paul M 3rd\|Camalier, Corinne E\|Mehaffey, Michele G\|Furman, Wayne L\|Bahrami, Armita\|Williams, P Mickey\|Lih, Chih-Jian\|Conley, Barbara A\|Khan, Javed
PMID:	29194591

159.
Journal:	Cell Death Dis. 2018 Jan 19;9(2):44.
Title:	Insight into the role of PIKK family members and NF-small ka, CyrillicB in DNAdamage-induced senescence and senescence-associated secretory phenotype of colon cancer cells.
Author:	Strzeszewska, Anna\|Alster, Olga\|Mosieniak, Grazyna\|Ciolko, Agata\|Sikora, Ewa
PMID:	29352261

160.
Journal:	Int J Radiat Biol. 2018 Apr;94(4):327-334.
Title:	53BP1 loss suppresses the radiosensitizing effect of icotinib hydrochloride in colorectal cancer cells.
Author:	Huang, Ai\|Yao, Jing\|Liu, Tao\|Lin, Zhenyu\|Zhang, Sheng\|Zhang, Tao\|Ma, Hong
PMID:	29388453

161.
Journal:	Am J Hum Genet. 2018 Mar 1;102(3):401-414.
Title:	Inherited DNA-Repair Defects in Colorectal Cancer.
Author:	AlDubayan, Saud H\|Giannakis, Marios\|Moore, Nathanael D\|Han, G Celine\|Reardon, Brendan\|Hamada, Tsuyoshi\|Mu, Xinmeng Jasmine\|Nishihara, Reiko\|Qian, Zhirong\|Liu, Li\|Yurgelun, Matthew B\|Syngal, Sapna\|Garraway, Levi A\|Ogino, Shuji\|Fuchs, Charles S\|Van Allen, E
PMID:	29478780

162.
Journal:	Genes Chromosomes Cancer. 2018 Jul;57(7):366-376.
Title:	Mutation analysis of adenomas and carcinomas of the colon: Early and late drivers.
Author:	Wolff, Roger K\|Hoffman, Michael D\|Wolff, Erica C\|Herrick, Jennifer S\|Sakoda, Lori C\|Samowitz, Wade S\|Slattery, Martha L
PMID:	29575536

163.
Journal:	Anticancer Res. 2018 Apr;38(4):2235-2240.
Title:	Racial Disparities in the Molecular Landscape of Cancer.
Author:	Heath, Elisabeth I\|Lynce, Filipa\|Xiu, Joanne\|Ellerbrock, Angela\|Reddy, Sandeep K\|Obeid, Elias\|Liu, Stephen V\|Bollig-Fischer, Aliccia\|Separovic, Duska\|Vanderwalde, Ari
PMID:	29599344

164.
Journal:	JAMA Oncol. 2018 Aug 1;4(8):1085-1092.
Title:	Immune Profiling of Premalignant Lesions in Patients With Lynch Syndrome.
Author:	Chang, Kyle\|Taggart, Melissa W\|Reyes-Uribe, Laura\|Borras, Ester\|Riquelme, Erick\|Barnett, Reagan M\|Leoni, Guido\|San Lucas, F Anthony\|Catanese, Maria T\|Mori, Federica\|Diodoro, Maria G\|You, Y Nancy\|Hawk, Ernest T\|Roszik, Jason\|Scheet, Paul\|Kopetz, Scott\|Nico
PMID:	29710228

165.
Journal:	Acta Pharmacol Sin. 2018 May 31. pii: aps2017192.
Title:	Escin-induced DNA damage promotes escin-induced apoptosis in human colorectal cancer cells via p62 regulation of the ATM/gammaH2AX pathway.
Author:	Wang, Zhong\|Chen, Qiang\|Li, Bin\|Xie, Jia-Ming\|Yang, Xiao-Dong\|Zhao, Kui\|Wu, Yong\|Ye, Zhen-Yu\|Chen, Zheng-Rong\|Qin, Zheng-Hong\|Xing, Chun-Gen
PMID:	29849127

166.
Journal:	PLoS One. 2018 Jun 5;13(6):e0197154.
Title:	The expression of telomere-related proteins and DNA damage response and their association with telomere length in colorectal cancer in Saudi patients.
Author:	Aljarbou, Ftoon\|Almousa, Nourah\|Bazzi, Mohammad\|Aldaihan, Sooad\|Alanazi, Mohammed\|Alharbi, Othman\|Almadi, Majid\|Aljebreen, Abdulrahman M\|Azzam, Nahla Ali\|Arafa, Maha\|Aldbass, Abeer\|Shaik, Jilani\|Alasirri, Shaheerah\|Warsy, Arjumand\|Alamri, Abdullah\|Parine,
PMID:	29870526

167.
Journal:	Acta Pharmacol Sin. 2018 Jun 19. pii: 10.1038/s41401-018-0047-1.
Title:	Aescin-induced reactive oxygen species play a pro-survival role in human cancer cells via ATM/AMPK/ULK1-mediated autophagy.
Author:	Li, Bin\|Wu, Guo-Liang\|Dai, Wei\|Wang, Gang\|Su, Hao-Yuan\|Shen, Xue-Ping\|Zhan, Rui\|Xie, Jia-Ming\|Wang, Zhong\|Qin, Zheng-Hong\|Gao, Quan-Gen\|Shen, Gen-Hai
PMID:	29921885

168.
Journal:	Oncotarget. 2018 Jan 23;9(42):26616-26624.
Title:	Association of genetic variants in ATR-CHEK1 and ATM-CHEK2 pathway genes with risk of colorectal cancer in a Chinese population.
Author:	Wang, Shijia\|Zhang, Yue\|Chen, Min\|Wang, Yong\|Feng, Yifei\|Xu, Ziwei\|Zhang, Dongsheng\|Sun, Yueming\|Fu, Zan
PMID:	29928473

169.
Journal:	J Pathol. 2018 Oct;246(2):134-140.
Title:	Geminin ablation in vivo enhances tumorigenesis through increased genomic instability.
Author:	Champeris Tsaniras, Spyridon\|Villiou, Maria\|Giannou, Anastassios D\|Nikou, Sofia\|Petropoulos, Michalis\|Pateras, Ioannis S\|Tserou, Paraskevi\|Karousi, Foteini\|Lalioti, Maria-Eleni\|Gorgoulis, Vassilis G\|Patmanidi, Alexandra L\|Stathopoulos, Georgios T\|Bravou,
PMID:	29952003

170.
Journal:	Oncotarget. 2018 Jun 12;9(45):27835-27850.
Title:	Survivin antagonizes chemotherapy-induced cell death of colorectal cancer cells.
Author:	Rauch, Anke\|Carlstedt, Annemarie\|Emmerich, Claudia\|Mustafa, Al-Hassan M\|Goder, Anja\|Knauer, Shirley K\|Linnebacher, Michael\|Heinzel, Thorsten\|Kramer, Oliver H
PMID:	29963241

171.
Journal:	Cancer Res. 2018 Sep 1;78(17):5072-5083.
Title:	A Novel Inhibitor Targets Both Wnt Signaling and ATM/p53 in Colorectal Cancer.
Author:	Cheng, Jiongjia\|Dwyer, Mary\|Okolotowicz, Karl J\|Mercola, Mark\|Cashman, John R
PMID:	30032112

172.
Journal:	Clin Colorectal Cancer. 2018 Jun 8. pii: S1533-0028(18)30141-5.
Title:	Ataxia Telangiectasia Mutated Protein Loss and Benefit From Oxaliplatin-based Chemotherapy in Colorectal Cancer.
Author:	Sundar, Raghav\|Miranda, Susana\|Rodrigues, Daniel Nava\|Chenard-Poirier, Maxime\|Dolling, David\|Clarke, Matthew\|Figueiredo, Ines\|Bertan, Claudia\|Yuan, Wei\|Ferreira, Ana\|Chistova, Rossitza\|Boysen, Gunther\|Perez, Desamparados Roda\|Tunariu, Nina\|Mateo, Joaquin\|
PMID:	30042009

173.
Journal:	Lancet Gastroenterol Hepatol. 2018 Sep;3(9):635-643.
Title:	Mutation burden and other molecular markers of prognosis in colorectal cancer treated with curative intent: results from the QUASAR 2 clinical trial and an Australian community-based series.
Author:	Domingo, Enric\|Camps, Carme\|Kaisaki, Pamela J\|Parsons, Marie J\|Mouradov, Dmitri\|Pentony, Melissa M\|Makino, Seiko\|Palmieri, Michelle\|Ward, Robyn L\|Hawkins, Nicholas J\|Gibbs, Peter\|Askautrud, Hanne\|Oukrif, Dahmane\|Wang, Haitao\|Wood, Joe\|Tomlinson, Evie\|Bark
PMID:	30042065

174.
Journal:	Int J Oncol. 2018 Oct;53(4):1667-1680.
Title:	Radiosensitization by irinotecan is attributed to G2/M phase arrest, followed by enhanced apoptosis, probably through the ATM/Chk/Cdc25C/Cdc2 pathway in p53-mutant colorectal cancer cells.
Author:	Wang, Yaqi\|Yang, Lifeng\|Zhang, Jing\|Zhou, Menglong\|Shen, Lijun\|Deng, Weijuan\|Liang, Liping\|Hu, Ran\|Yang, Wang\|Yao, Ye\|Zhang, Hui\|Zhang, Zhen
PMID:	30085332

175.
Journal:	Oncol Lett. 2018 Oct;16(4):4671-4678.
Title:	Chaetominine induces cell cycle arrest in human leukemia K562 and colon cancer SW1116 cells.
Author:	Yao, Jingyun\|Xiao, Jianbo\|Wei, Xing\|Lu, Yanhua
PMID:	30214601

176.
Journal:	Clin Colorectal Cancer. 2018 Sep 13. pii: S1533-0028(18)30431-6.
Title:	ATM Is Required for the Repair of Oxaliplatin-Induced DNA Damage in Colorectal Cancer.
Author:	Bakkenist, Christopher J\|Lee, James J\|Schmitz, John C
PMID:	30316683

177.
Journal:	Br J Cancer. 2018 Nov 2. pii: 10.1038/s41416-018-0286-4.
Title:	pRAD50: a novel and clinically applicable pharmacodynamic biomarker of both ATM and ATR inhibition identified using mass spectrometry and immunohistochemistry.
Author:	Jones, Gemma N\|Rooney, Claire\|Griffin, Nicola\|Roudier, Martine\|Young, Lucy A\|Garcia-Trinidad, Antonio\|Hughes, Gareth D\|Whiteaker, Jeffrey R\|Wilson, Zena\|Odedra, Rajesh\|Zhao, Lei\|Ivey, Richard G\|Howat, William J\|Harrington, Elizabeth A\|Barrett, J Carl\|Ramo
PMID:	30385821