Primary Site >> Colorectal Cancer
Gene >> ATG7
| 1. | |||||||||||
| Journal: | Cancer Res. 2007 Oct 15;67(20):9677-84. | ||||||||||
| Title: | Autophagy is activated in colorectal cancer cells and contributes to the tolerance to nutrient deprivation. | ||||||||||
| Author: | Sato, Kazunori|Tsuchihara, Katsuya|Fujii, Satoshi|Sugiyama, Masanori|Goya, Tomoyuki|Atomi, Yutaka|Ueno, Takashi|Ochiai, Atsushi|Esumi, Hiroyasu | ||||||||||
| PMID: | 17942897 | ||||||||||
| 2. | |||||||||||
| Journal: | J Cell Mol Med. 2010 Oct;14(10):2448-59. | ||||||||||
| Title: | Autophagy inhibition enhances vorinostat-induced apoptosis via ubiquitinated protein accumulation. | ||||||||||
| Author: | Carew, Jennifer S|Medina, Ernest C|Esquivel, Juan A 2nd|Mahalingam, Devalingam|Swords, Ronan|Kelly, Kevin|Zhang, Hui|Huang, Peng|Mita, Alain C|Mita, Monica M|Giles, Francis J|Nawrocki, Steffan T | ||||||||||
| PMID: | 19583815 | ||||||||||
| 3. | |||||||||||
| Journal: | Autophagy. 2010 Jan;6(1):46-60. Epub 2010 Jan 13. | ||||||||||
| Title: | Bacillus calmette-guerin cell wall cytoskeleton enhances colon cancer radiosensitivity through autophagy. | ||||||||||
| Author: | Yuk, Jae-Min|Shin, Dong-Min|Song, Kyoung-Sub|Lim, Kyu|Kim, Ki-Hye|Lee, Sang-Hee|Kim, Jin-Man|Lee, Ji-Sook|Paik, Tae-Hyun|Kim, Jun-Sang|Jo, Eun-Kyeong | ||||||||||
| PMID: | 19901560 | ||||||||||
| 4. | |||||||||||
| Journal: | PLoS One. 2010 Jan 18;5(1):e8755. | ||||||||||
| Title: | Differential dependence on Beclin 1 for the regulation of pro-survival autophagy by Bcl-2 and Bcl-xL in HCT116 colorectal cancer cells. | ||||||||||
| Author: | Priault, Muriel|Hue, Erika|Marhuenda, Fanny|Pilet, Paul|Oliver, Lisa|Vallette, Francois M | ||||||||||
| PMID: | 20090905 | ||||||||||
| 5. | |||||||||||
| Journal: | Eur J Cancer. 2010 Jul;46(10):1900-9. | ||||||||||
| Title: | Inhibition of autophagy augments 5-fluorouracil chemotherapy in human colon cancer in vitro and in vivo model. | ||||||||||
| Author: | Li, Jie|Hou, Ni|Faried, Ahmad|Tsutsumi, Soichi|Kuwano, Hiroyuki | ||||||||||
| PMID: | 20231086 | ||||||||||
| 6. | |||||||||||
| Journal: | Nat Cell Biol. 2010 Jul;12(7):665-75. | ||||||||||
| Title: | Cytosolic FoxO1 is essential for the induction of autophagy and tumour suppressor activity. | ||||||||||
| Author: | Zhao, Ying|Yang, Jing|Liao, Wenjuan|Liu, Xiangyu|Zhang, Hui|Wang, Shan|Wang, Donglai|Feng, Jingnan|Yu, Li|Zhu, Wei-Guo | ||||||||||
| PMID: | 20543840 | ||||||||||
| 7. | |||||||||||
| Journal: | Cell Death Differ. 2011 Apr;18(4):602-18. | ||||||||||
| Title: | Short-chain fatty acids induced autophagy serves as an adaptive strategy for retarding mitochondria-mediated apoptotic cell death. | ||||||||||
| Author: | Tang, Y|Chen, Y|Jiang, H|Nie, D | ||||||||||
| PMID: | 20930850 | ||||||||||
| 8. | |||||||||||
| Journal: | Free Radic Biol Med. 2012 Aug 1;53(3):532-43. | ||||||||||
| Title: | P38 MAP kinase functions as a switch in MS-275-induced reactive oxygen species-dependent autophagy and apoptosis in human colon cancer cells. | ||||||||||
| Author: | Zhan, Yao|Gong, Ke|Chen, Chao|Wang, Haiqing|Li, Wenhua | ||||||||||
| PMID: | 22634147 | ||||||||||
| 9. | |||||||||||
| Journal: | PLoS One. 2012;7(5):e37572. | ||||||||||
| Title: | Hydrogen sulfide lowers proliferation and induces protective autophagy in colon epithelial cells. | ||||||||||
| Author: | Wu, Ya C|Wang, Xiao J|Yu, Le|Chan, Francis K L|Cheng, Alfred S L|Yu, Jun|Sung, Joseph J Y|Wu, William K K|Cho, Chi H | ||||||||||
| PMID: | 22679478 | ||||||||||
| 10. | |||||||||||
| Journal: | J Pharmacol Exp Ther. 2012 Dec;343(3):763-78. | ||||||||||
| Title: | The autophagy-senescence connection in chemotherapy: must tumor cells (self) eat before they sleep? | ||||||||||
| Author: | Goehe, Rachel W|Di, Xu|Sharma, Khushboo|Bristol, Molly L|Henderson, Scott C|Valerie, Kristoffer|Rodier, Francis|Davalos, Albert R|Gewirtz, David A | ||||||||||
| PMID: | 22927544 | ||||||||||
| 11. | |||||||||||
| Journal: | PLoS Genet. 2013 Apr;9(4):e1003464. | ||||||||||
| Title: | Breakpoint analysis of transcriptional and genomic profiles uncovers novel gene fusions spanning multiple human cancer types. | ||||||||||
| Author: | Giacomini, Craig P|Sun, Steven|Varma, Sushama|Shain, A Hunter|Giacomini, Marilyn M|Balagtas, Jay|Sweeney, Robert T|Lai, Everett|Del Vecchio, Catherine A|Forster, Andrew D|Clarke, Nicole|Montgomery, Kelli D|Zhu, Shirley|Wong, Albert J|van de Rijn, Matt|Wes | ||||||||||
| PMID: | 23637631 | ||||||||||
| 12. | |||||||||||
| Journal: | Autophagy. 2013 Dec;9(12):2126-39. | ||||||||||
| Title: | BIX-01294 induces autophagy-associated cell death via EHMT2/G9a dysfunction and intracellular reactive oxygen species production. | ||||||||||
| Author: | Kim, Yunha|Kim, Yong-Sook|Kim, Dong Eun|Lee, Jee Suk|Song, Ji Hoon|Kim, Ha-Gyeong|Cho, Dong-Hyung|Jeong, Seong-Yun|Jin, Dong-Hoon|Jang, Se Jin|Seol, Hyang-Sook|Suh, Young-Ah|Lee, Seung Jin|Kim, Choung-Soo|Koh, Jae-Young|Hwang, Jung Jin | ||||||||||
| PMID: | 24322755 | ||||||||||
| 13. | |||||||||||
| Journal: | Cell Death Dis. 2013 Aug 1;4:e750. | ||||||||||
| Title: | A ginseng metabolite, compound K, induces autophagy and apoptosis via generation of reactive oxygen species and activation of JNK in human colon cancer cells. | ||||||||||
| Author: | Kim, A D|Kang, K A|Kim, H S|Kim, D H|Choi, Y H|Lee, S J|Kim, H S|Hyun, J W | ||||||||||
| PMID: | 23907464 | ||||||||||
| 14. | |||||||||||
| Journal: | PLoS One. 2013 May 20;8(5):e63641. | ||||||||||
| Title: | FK-16 derived from the anticancer peptide LL-37 induces caspase-independent apoptosis and autophagic cell death in colon cancer cells. | ||||||||||
| Author: | Ren, Shun X|Shen, Jin|Cheng, Alfred S L|Lu, Lan|Chan, Ruby L Y|Li, Zhi J|Wang, Xiao J|Wong, Clover C M|Zhang, Lin|Ng, Simon S M|Chan, Franky L|Chan, Francis K L|Yu, Jun|Sung, Joseph J Y|Wu, William K K|Cho, Chi H | ||||||||||
| PMID: | 23700428 | ||||||||||
| 15. | |||||||||||
| Journal: | Oncogene. 2014 Oct 2;33(40):4847-56. | ||||||||||
| Title: | microRNA-18a induces apoptosis in colon cancer cells via the autophagolysosomal degradation of oncogenic heterogeneous nuclear ribonucleoprotein A1. | ||||||||||
| Author: | Fujiya, M|Konishi, H|Mohamed Kamel, M K|Ueno, N|Inaba, Y|Moriichi, K|Tanabe, H|Ikuta, K|Ohtake, T|Kohgo, Y | ||||||||||
| PMID: | 24166503 | ||||||||||
| 16. | |||||||||||
| Journal: | Autophagy. 2014 Jul;10(7):1179-92. | ||||||||||
| Title: | Autophagy promotes resistance to photodynamic therapy-induced apoptosis selectively in colorectal cancer stem-like cells. | ||||||||||
| Author: | Wei, Ming-Feng|Chen, Min-Wei|Chen, Ke-Cheng|Lou, Pei-Jen|Lin, Susan Yun-Fan|Hung, Shih-Chieh|Hsiao, Michael|Yao, Cheng-Jung|Shieh, Ming-Jium | ||||||||||
| PMID: | 24905352 | ||||||||||
| 17. | |||||||||||
| Journal: | Exp Mol Med. 2014 Dec 5;46:e124. | ||||||||||
| Title: | Inhibition of phospholipase D2 induces autophagy in colorectal cancer cells. | ||||||||||
| Author: | Hwang, Won Chan|Kim, Mi Kyoung|Song, Ju Hyun|Choi, Kang-Yell|Min, Do Sik | ||||||||||
| PMID: | 25475140 | ||||||||||
| 18. | |||||||||||
| Journal: | BMC Cancer. 2015 Nov 19;15:919. | ||||||||||
| Title: | Pan-Bcl-2 inhibitor Obatoclax is a potent late stage autophagy inhibitor in colorectal cancer cells independent of canonical autophagy signaling. | ||||||||||
| Author: | Koehler, Bruno Christian|Jassowicz, Adam|Scherr, Anna-Lena|Lorenz, Stephan|Radhakrishnan, Praveen|Kautz, Nicole|Elssner, Christin|Weiss, Johanna|Jaeger, Dirk|Schneider, Martin|Schulze-Bergkamen, Henning | ||||||||||
| PMID: | 26585594 | ||||||||||
| 19. | |||||||||||
| Journal: | Eur J Pharmacol. 2015 Oct 15;765:217-27. | ||||||||||
| Title: | Blockade of autophagy enhances proapoptotic potential of BI-69A11, a novel Akt inhibitor, in colon carcinoma. | ||||||||||
| Author: | Pal, Ipsita|Parida, Sheetal|Prashanth Kumar, B N|Banik, Payel|Kumar Dey, Kaushik|Chakraborty, Sandipan|Bhutia, Sujit K|Mandal, Mahitosh | ||||||||||
| PMID: | 26306675 | ||||||||||
| 20. | |||||||||||
| Journal: | Nat Cell Biol. 2015 Aug;17(8):1062-73. | ||||||||||
| Title: | Intestinal inhibition of Atg7 prevents tumour initiation through a microbiome-influenced immune response and suppresses tumour growth. | ||||||||||
| Author: | Levy, Jonathan|Cacheux, Wulfran|Bara, Medhi Ait|L'Hermitte, Antoine|Lepage, Patricia|Fraudeau, Marie|Trentesaux, Coralie|Lemarchand, Julie|Durand, Aurelie|Crain, Anne-Marie|Marchiol, Carmen|Renault, Gilles|Dumont, Florent|Letourneur, Franck|Delacre, Myria | ||||||||||
| PMID: | 26214133 | ||||||||||
| 21. | |||||||||||
| Journal: | Int J Mol Sci. 2015 Jan 9;16(1):1544-61. | ||||||||||
| Title: | Defective autophagosome formation in p53-null colorectal cancer reinforces crocin-induced apoptosis. | ||||||||||
| Author: | Amin, Amr|Bajbouj, Khuloud|Koch, Adrian|Gandesiri, Muktheshwar|Schneider-Stock, Regine | ||||||||||
| PMID: | 25584615 | ||||||||||
| 22. | |||||||||||
| Journal: | Mol Med Rep. 2015 Apr;11(4):3160-6. | ||||||||||
| Title: | Sann-Joong-Kuey-Jian-Tang decreases the protein expression of mammalian target of rapamycin but increases microtubule associated protein II light chain 3 expression to inhibit human BxPC3 pancreatic carcinoma cells. | ||||||||||
| Author: | Su, Chin-Cheng | ||||||||||
| PMID: | 25516264 | ||||||||||
| 23. | |||||||||||
| Journal: | Autophagy. 2015;11(8):1230-46. | ||||||||||
| Title: | Upregulation of ATG3 contributes to autophagy induced by the detachment of intestinal epithelial cells from the extracellular matrix, but promotes autophagy-independent apoptosis of the attached cells. | ||||||||||
| Author: | Yoo, Byong Hoon|Zagryazhskaya, Anna|Li, Yongling|Koomson, Ananda|Khan, Iman Aftab|Sasazuki, Takehiko|Shirasawa, Senji|Rosen, Kirill V | ||||||||||
| PMID: | 26061804 | ||||||||||
| 24. | |||||||||||
| Journal: | Free Radic Biol Med. 2016 Jan;90:158-72. | ||||||||||
| Title: | DHA-induced stress response in human colon cancer cells - Focus on oxidative stress and autophagy. | ||||||||||
| Author: | Pettersen, Kristine|Monsen, Vivi Talstad|Hakvag Pettersen, Caroline Hild|Overland, Hilde Bremseth|Pettersen, Grete|Samdal, Helle|Tesfahun, Almaz Nigatu|Lundemo, Anne Goril|Bjorkoy, Geir|Schonberg, Svanhild A | ||||||||||
| PMID: | 26585906 | ||||||||||
| 25. | |||||||||||
| Journal: | Oncotarget. 2016 Jul 19;7(29):45112-45121. | ||||||||||
| Title: | Enhanced autophagy in colorectal cancer stem cells does not contribute to radio-resistance. | ||||||||||
| Author: | Yan, Chen|Luo, Lan|Goto, Shinji|Urata, Yoshishige|Guo, Chang-Ying|Doi, Hanako|Kitazato, Kaio|Li, Tao-Sheng | ||||||||||
| PMID: | 27129175 | ||||||||||
| 26. | |||||||||||
| Journal: | Mol Med Rep. 2016 Sep;14(3):2548-54. | ||||||||||
| Title: | Co-expression of autophagic markers following photodynamic therapy in SW620 human colon adenocarcinoma cells. | ||||||||||
| Author: | Ziolkowska, Barbara|Wozniak, Marta|Ziolkowski, Piotr | ||||||||||
| PMID: | 27485939 | ||||||||||
| 27. | |||||||||||
| Journal: | Cell Death Dis. 2016 Aug 11;7(8):e2334. | ||||||||||
| Title: | Ginsenoside compound K sensitizes human colon cancer cells to TRAIL-induced apoptosis via autophagy-dependent and -independent DR5 upregulation. | ||||||||||
| Author: | Chen, Lei|Meng, Yue|Sun, Qi|Zhang, Zhongyu|Guo, Xiaoqing|Sheng, Xiaotong|Tai, Guihua|Cheng, Hairong|Zhou, Yifa | ||||||||||
| PMID: | 27512955 | ||||||||||
| 28. | |||||||||||
| Journal: | Am J Cancer Res. 2016 Aug 1;6(8):1661-80. eCollection 2016. | ||||||||||
| Title: | EZH2 inhibitors transcriptionally upregulate cytotoxic autophagy and cytoprotective unfolded protein response in human colorectal cancer cells. | ||||||||||
| Author: | Hsieh, Yao-Yu|Lo, Hsiang-Ling|Yang, Pei-Ming | ||||||||||
| PMID: | 27648357 | ||||||||||
| 29. | |||||||||||
| Journal: | Eur J Cancer. 2016 Nov;68:38-50. | ||||||||||
| Title: | 6-C-(E-phenylethenyl)naringenin induces cell growth inhibition and cytoprotective autophagy in colon cancer cells. | ||||||||||
| Author: | Zhao, Yueliang|Fan, Daming|Ru, Beibei|Cheng, Ka-Wing|Hu, Shuting|Zhang, Jiangwen|Li, Edmund T S|Wang, Mingfu | ||||||||||
| PMID: | 27710830 | ||||||||||
| 30. | |||||||||||
| Journal: | Oncotarget. 2017 Jan 24;8(4):6419-6432. | ||||||||||
| Title: | Autophagy inhibition enhances photocytotoxicity of Photosan-II in human colorectal cancer cells. | ||||||||||
| Author: | Xiong, Li|Liu, Zhipeng|Ouyang, Guoqing|Lin, Liangwu|Huang, He|Kang, Hongxiang|Chen, Wei|Miao, Xiongying|Wen, Yu | ||||||||||
| PMID: | 28031534 | ||||||||||
| 31. | |||||||||||
| Journal: | Oncotarget. 2017 Aug 3;8(51):88563-88574. | ||||||||||
| Title: | Traditional Chinese medicine Danggui Buxue Tang inhibits colorectal cancer growth through induction of autophagic cell death. | ||||||||||
| Author: | Chen, Shun-Ting|Lee, Tzung-Yan|Tsai, Tung-Hu|Huang, Yu-Chuen|Lin, Yin-Cheng|Lin, Chin-Ping|Shieh, Hui-Ru|Hsu, Ming-Ling|Chi, Chih-Wen|Lee, Ming-Cheng|Chang, Hen-Hong|Chen, Yu-Jen | ||||||||||
| PMID: | 29179457 | ||||||||||
| 32. | |||||||||||
| Journal: | Rom J Morphol Embryol. 2017;58(1):27-31. | ||||||||||
| Title: | Autophagy in aging and disease. | ||||||||||
| Author: | Filfan, Madalina|Sandu, Raluca Elena|Zavaleanu, Alexandra Daniela|GresiTa, Andrei|Glavan, Daniela Gabriela|Olaru, Denissa Greta|Popa-Wagner, Aurel | ||||||||||
| PMID: | 28523294 | ||||||||||
| 33. | |||||||||||
| Journal: | Cell Death Dis. 2017 May 11;8(5):e2789. | ||||||||||
| Title: | Halofuginone dually regulates autophagic flux through nutrient-sensing pathways in colorectal cancer. | ||||||||||
| Author: | Chen, Guo-Qing|Gong, Rui-Hong|Yang, Da-Jian|Zhang, Ge|Lu, Ai-Ping|Yan, Siu-Cheong|Lin, Shu-Hai|Bian, Zhao-Xiang | ||||||||||
| PMID: | 28492544 | ||||||||||
| 34. | |||||||||||
| Journal: | Cell Death Differ. 2017 Jun;24(6):1045-1062. | ||||||||||
| Title: | mTORC1-independent autophagy regulates receptor tyrosine kinase phosphorylation in colorectal cancer cells via an mTORC2-mediated mechanism. | ||||||||||
| Author: | Lampada, Aikaterini|O'Prey, James|Szabadkai, Gyorgy|Ryan, Kevin M|Hochhauser, Daniel|Salomoni, Paolo | ||||||||||
| PMID: | 28475179 | ||||||||||
| 35. | |||||||||||
| Journal: | Cell Physiol Biochem. 2017;41(5):1851-1864. | ||||||||||
| Title: | Osteopontin Promotes Cell Migration and Invasion, and Inhibits Apoptosis and Autophagy in Colorectal Cancer by activating the p38 MAPK Signaling Pathway. | ||||||||||
| Author: | Huang, Ren-Hong|Quan, Ying-Jun|Chen, Jin-Hong|Wang, Ting-Feng|Xu, Ming|Ye, Min|Yuan, Hao|Zhang, Chong-Jie|Liu, Xiao-Jian|Min, Zhi-Jun | ||||||||||
| PMID: | 28376477 | ||||||||||
| 36. | |||||||||||
| Journal: | Oncotarget. 2017 Mar 7;8(10):16633-16641. | ||||||||||
| Title: | microRNA-375 inhibits colorectal cancer cells proliferation by downregulating JAK2/STAT3 and MAP3K8/ERK signaling pathways. | ||||||||||
| Author: | Wei, Ran|Yang, Qin|Han, Bing|Li, Yan|Yao, Kun|Yang, Xiuyu|Chen, Zexi|Yang, Shanshan|Zhou, Jiaqi|Li, Meizhang|Yu, Haijing|Yu, Min|Cui, Qinghua | ||||||||||
| PMID: | 28186962 | ||||||||||
| 37. | |||||||||||
| Journal: | Med Mol Morphol. 2017 Jun;50(2):76-85. | ||||||||||
| Title: | miR-106a suppresses tumor cells death in colorectal cancer through targeting ATG7. | ||||||||||
| Author: | Hao, Haibin|Xia, Guangfeng|Wang, Chao|Zhong, Fuping|Liu, Laipeng|Zhang, Dong | ||||||||||
| PMID: | 27981410 | ||||||||||
| 38. | |||||||||||
| Journal: | Cancer Lett. 2017 Mar 1;388:34-42. | ||||||||||
| Title: | Doxorubicin-induced mitophagy contributes to drug resistance in cancer stem cells from HCT8 human colorectal cancer cells. | ||||||||||
| Author: | Yan, Chen|Luo, Lan|Guo, Chang-Ying|Goto, Shinji|Urata, Yoshishige|Shao, Jiang-Hua|Li, Tao-Sheng | ||||||||||
| PMID: | 27913197 | ||||||||||
| 39. | |||||||||||
| Journal: | Photodiagnosis Photodyn Ther. 2018 Mar;21:396-403. | ||||||||||
| Title: | Inhibition of autophagy potentiates the apoptosis-inducing effects of photodynamic therapy on human colon cancer cells. | ||||||||||
| Author: | Ouyang, Guoqing|Xiong, Li|Liu, Zhipeng|Lam, Brandon|Bui, Brian|Ma, Lun|Chen, Xiang|Zhou, Pan|Wang, Kunpeng|Zhang, Zijian|Huang, He|Miao, Xiongying|Chen, Wei|Wen, Yu | ||||||||||
| PMID: | 29355734 | ||||||||||
| 40. | |||||||||||
| Journal: | J Cell Commun Signal. 2018 Jan 24. pii: 10.1007/s12079-018-0454-6. | ||||||||||
| Title: | Autophagic flux is essential for the downregulation of D-dopachrome tautomerase by atractylenolide I to ameliorate intestinal adenoma formation. | ||||||||||
| Author: | Li, Lu|Jing, Linlin|Wang, Junjiang|Xu, Wenjuan|Gong, Xianling|Zhao, Yiye|Ma, Ye|Yao, Xueqing|Sun, Xuegang | ||||||||||
| PMID: | 29368299 | ||||||||||
| 41. | |||||||||||
| Journal: | PLoS One. 2018 Aug 27;13(8):e0202856. | ||||||||||
| Title: | Opposite functions of GSN and OAS2 on colorectal cancer metastasis, mediating perineural and lymphovascular invasion, respectively. | ||||||||||
| Author: | Kim, Jin Cheon|Ha, Ye Jin|Tak, Ka Hee|Roh, Seon Ae|Kwon, Yi Hong|Kim, Chan Wook|Yoon, Yong Sik|Lee, Jong Lyul|Park, Yangsoon|Kim, Seon-Kyu|Kim, Seon-Young|Cho, Dong-Hyung|Kim, Yong Sung | ||||||||||
| PMID: | 30148861 | ||||||||||
| 42. | |||||||||||
| Journal: | Med Oncol. 2018 Oct 29;35(12):159. | ||||||||||
| Title: | The Influence of Tumor Microenvironment on ATG4D Gene Expression in Colorectal Cancer Patients. | ||||||||||
| Author: | Gil, Justyna|Ramsey, David|Pawlowski, Pawel|Szmida, Elzbieta|Leszczynski, Przemyslaw|Bebenek, Marek|Sasiadek, Maria M | ||||||||||
| PMID: | 30374741 | ||||||||||