Primary Site >> Colorectal Cancer
Gene >> ATG7
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Ref: Autophagy is activated in colorectal cancer cells and contributes to the tolerance to nutrient deprivation. PMID: 17942897 |
Ref: Autophagy inhibition enhances vorinostat-induced apoptosis via ubiquitinated protein accumulation. PMID: 19583815 Ref: Bacillus calmette-guerin cell wall cytoskeleton enhances colon cancer radiosensitivity through autophagy. PMID: 19901560 Ref: Differential dependence on Beclin 1 for the regulation of pro-survival autophagy by Bcl-2 and Bcl-xL in HCT116 colorectal cancer cells. PMID: 20090905 Ref: Inhibition of autophagy augments 5-fluorouracil chemotherapy in human colon cancer in vitro and in vivo model. PMID: 20231086 Ref: Cytosolic FoxO1 is essential for the induction of autophagy and tumour suppressor activity. PMID: 20543840 |
Ref: Short-chain fatty acids induced autophagy serves as an adaptive strategy for retarding mitochondria-mediated apoptotic cell death. PMID: 20930850 |
Ref: P38 MAP kinase functions as a switch in MS-275-induced reactive oxygen species-dependent autophagy and apoptosis in human colon cancer cells. PMID: 22634147 Ref: Hydrogen sulfide lowers proliferation and induces protective autophagy in colon epithelial cells. PMID: 22679478 Ref: The autophagy-senescence connection in chemotherapy: must tumor cells (self) eat before they sleep? PMID: 22927544 |
Ref: Breakpoint analysis of transcriptional and genomic profiles uncovers novel gene fusions spanning multiple human cancer types. PMID: 23637631 Ref: FK-16 derived from the anticancer peptide LL-37 induces caspase-independent apoptosis and autophagic cell death in colon cancer cells. PMID: 23700428 Ref: A ginseng metabolite, compound K, induces autophagy and apoptosis via generation of reactive oxygen species and activation of JNK in human colon cancer cells. PMID: 23907464 Ref: BIX-01294 induces autophagy-associated cell death via EHMT2/G9a dysfunction and intracellular reactive oxygen species production. PMID: 24322755 |
Ref: microRNA-18a induces apoptosis in colon cancer cells via the autophagolysosomal degradation of oncogenic heterogeneous nuclear ribonucleoprotein A1. PMID: 24166503 Ref: Autophagy promotes resistance to photodynamic therapy-induced apoptosis selectively in colorectal cancer stem-like cells. PMID: 24905352 Ref: Inhibition of phospholipase D2 induces autophagy in colorectal cancer cells. PMID: 25475140 |
Ref: Sann-Joong-Kuey-Jian-Tang decreases the protein expression of mammalian target of rapamycin but increases microtubule associated protein II light chain 3 expression to inhibit human BxPC3 pancreatic carcinoma cells. PMID: 25516264 Ref: Defective autophagosome formation in p53-null colorectal cancer reinforces crocin-induced apoptosis. PMID: 25584615 Ref: Upregulation of ATG3 contributes to autophagy induced by the detachment of intestinal epithelial cells from the extracellular matrix, but promotes autophagy-independent apoptosis of the attached cells. PMID: 26061804 Ref: Intestinal inhibition of Atg7 prevents tumour initiation through a microbiome-influenced immune response and suppresses tumour growth. PMID: 26214133 Ref: Blockade of autophagy enhances proapoptotic potential of BI-69A11, a novel Akt inhibitor, in colon carcinoma. PMID: 26306675 Ref: Pan-Bcl-2 inhibitor Obatoclax is a potent late stage autophagy inhibitor in colorectal cancer cells independent of canonical autophagy signaling. PMID: 26585594 |
Ref: DHA-induced stress response in human colon cancer cells - Focus on oxidative stress and autophagy. PMID: 26585906 Ref: Enhanced autophagy in colorectal cancer stem cells does not contribute to radio-resistance. PMID: 27129175 Ref: Co-expression of autophagic markers following photodynamic therapy in SW620 human colon adenocarcinoma cells. PMID: 27485939 Ref: Ginsenoside compound K sensitizes human colon cancer cells to TRAIL-induced apoptosis via autophagy-dependent and -independent DR5 upregulation. PMID: 27512955 Ref: EZH2 inhibitors transcriptionally upregulate cytotoxic autophagy and cytoprotective unfolded protein response in human colorectal cancer cells. PMID: 27648357 Ref: 6-C-(E-phenylethenyl)naringenin induces cell growth inhibition and cytoprotective autophagy in colon cancer cells. PMID: 27710830 |
Ref: Doxorubicin-induced mitophagy contributes to drug resistance in cancer stem cells from HCT8 human colorectal cancer cells. PMID: 27913197 Ref: miR-106a suppresses tumor cells death in colorectal cancer through targeting ATG7. PMID: 27981410 Ref: Autophagy inhibition enhances photocytotoxicity of Photosan-II in human colorectal cancer cells. PMID: 28031534 Ref: microRNA-375 inhibits colorectal cancer cells proliferation by downregulating JAK2/STAT3 and MAP3K8/ERK signaling pathways. PMID: 28186962 Ref: Osteopontin Promotes Cell Migration and Invasion, and Inhibits Apoptosis and Autophagy in Colorectal Cancer by activating the p38 MAPK Signaling Pathway. PMID: 28376477 Ref: mTORC1-independent autophagy regulates receptor tyrosine kinase phosphorylation in colorectal cancer cells via an mTORC2-mediated mechanism. PMID: 28475179 Ref: Halofuginone dually regulates autophagic flux through nutrient-sensing pathways in colorectal cancer. PMID: 28492544 Ref: Autophagy in aging and disease. PMID: 28523294 Ref: Traditional Chinese medicine Danggui Buxue Tang inhibits colorectal cancer growth through induction of autophagic cell death. PMID: 29179457 |
Ref: Inhibition of autophagy potentiates the apoptosis-inducing effects of photodynamic therapy on human colon cancer cells. PMID: 29355734 Ref: Autophagic flux is essential for the downregulation of D-dopachrome tautomerase by atractylenolide I to ameliorate intestinal adenoma formation. PMID: 29368299 Ref: Opposite functions of GSN and OAS2 on colorectal cancer metastasis, mediating perineural and lymphovascular invasion, respectively. PMID: 30148861 Ref: The Influence of Tumor Microenvironment on ATG4D Gene Expression in Colorectal Cancer Patients. PMID: 30374741 |