Primary Site >> Colorectal Cancer

Gene >> ATF4

Journal: J Natl Cancer Inst. 2004 Sep 1;96(17):1300-10.
Title: Effect on tumor cells of blocking survival response to glucose deprivation.
Author: Park, Hae-Ryong|Tomida, Akihiro|Sato, Shigeo|Tsukumo, Yoshinori|Yun, Jisoo|Yamori, Takao|Hayakawa, Yoichi|Tsuruo, Takashi|Shin-ya, Kazuo
PMID: 15339968
Journal: Cancer Res. 2007 Feb 1;67(3):1262-9.
Title: Inhibition of fatty acid synthase induces endoplasmic reticulum stress in tumor cells.
Author: Little, Joy L|Wheeler, Frances B|Fels, Diane R|Koumenis, Constantinos|Kridel, Steven J
PMID: 17283163
Journal: Int J Cancer. 2008 Aug 1;123(3):687-94.
Title: Growth inhibition of colon cancer cells by polyisoprenylated benzophenones is associated with induction of the endoplasmic reticulum response.
Author: Protiva, Petr|Hopkins, Michael E|Baggett, Scott|Yang, Hui|Lipkin, Martin|Holt, Peter R|Kennelly, Edward J|Bernard, Weinstein I
PMID: 18470880
Journal: BMC Cell Biol. 2009 Sep 15;10:64.
Title: Inhibition of eIF2alpha dephosphorylation inhibits ErbB2-induced deregulation of mammary acinar morphogenesis.
Author: Sequeira, Sharon J|Wen, Huei Chi|Avivar-Valderas, Alvaro|Farias, Eduardo F|Aguirre-Ghiso, Julio A
PMID: 19754954
Journal: J Cell Physiol. 2010 Jul;224(1):33-40.
Title: Arctigenin blocks the unfolded protein response and shows therapeutic antitumor activity.
Author: Kim, Ju-Young|Hwang, Ji-Hwan|Cha, Mi-Ran|Yoon, Mi-Young|Son, Eun-Soon|Tomida, Akihiro|Ko, Bosung|Song, Si-Whan|Shin-ya, Kazuo|Hwang, Yong-il|Park, Hae-Ryong
PMID: 20232300
Journal: Mol Cancer Ther. 2010 Jul;9(7):2007-15.
Title: ABT-737 overcomes resistance to immunotoxin-mediated apoptosis and enhances the delivery of pseudomonas exotoxin-based proteins to the cell cytosol.
Author: Traini, Roberta|Ben-Josef, Gal|Pastrana, Diana V|Moskatel, Elizabeth|Sharma, Ashima K|Antignani, Antonella|Fitzgerald, David J
PMID: 20587662
Journal: Biochim Biophys Acta. 2011 Jul;1809(7):306-15.
Title: Dickkopf homolog 1, a Wnt signaling antagonist, is transcriptionally up-regulated via an ATF4-independent and MAPK/ERK-dependent pathway following amino acid deprivation.
Author: Zhou, Dan|Zhang, Yukun|Pan, Yuan-Xiang|Chen, Hong
PMID: 21683813
Journal: Lipids Health Dis. 2011 Oct 25;10:190.
Title: Tetradecylthioacetic acid inhibits proliferation of human SW620 colon cancer cells--gene expression profiling implies endoplasmic reticulum stress.
Author: Lundemo, Anne G|Pettersen, Caroline H H|Berge, Kjetil|Berge, Rolf K|Schonberg, Svanhild A
PMID: 22027281
Journal: Biochem J. 2012 Jun 1;444(2):249-59.
Title: AMPK and GCN2-ATF4 signal the repression of mitochondria in colon cancer cells.
Author: Martinez-Reyes, Inmaculada|Sanchez-Arago, Maria|Cuezva, Jose M
PMID: 22435535
Journal: J Nutr Biochem. 2013 Apr;24(4):664-71.
Title: 3,3'-diindolylmethane induces activating transcription factor 3 (ATF3) via ATF4 in human colorectal cancer cells.
Author: Lee, Seong-Ho|Min, Kyung-Won|Zhang, Xiaobo|Baek, Seung Joon
PMID: 22819556
Journal: Toxicol In Vitro. 2013 Mar;27(2):588-96.
Title: Helenalin-induced apoptosis is dependent on production of reactive oxygen species and independent of induction of endoplasmic reticulum stress in renal cell carcinoma.
Author: Jang, Ji Hoon|Iqbal, Taha|Min, Kyoung-Jin|Kim, Shin|Park, Jong-Wook|Son, Eun-Ik|Lee, Tae-Jin|Kwon, Taeg Kyu
PMID: 23123298
Journal: Cancer Prev Res (Phila). 2013 Dec;6(12):1337-47.
Title: The involvement of endoplasmic reticulum stress in the suppression of colorectal tumorigenesis by tolfenamic acid.
Author: Zhang, Xiaobo|Lee, Seong-Ho|Min, Kyung-Won|McEntee, Michael F|Jeong, Jin Boo|Li, Qingwang|Baek, Seung Joon
PMID: 24104354
Journal: Cell Death Dis. 2013 Oct 10;4:e851.
Title: Translational control in the stress adaptive response of cancer cells: a novel role for the heat shock protein TRAP1.
Author: Matassa, D S|Amoroso, M R|Agliarulo, I|Maddalena, F|Sisinni, L|Paladino, S|Romano, S|Romano, M F|Sagar, V|Loreni, F|Landriscina, M|Esposito, F
PMID: 24113185
Journal: Biochim Biophys Acta. 2014 Jun;1840(6):1808-16.
Title: A new tellurium-containing amphiphilic molecule induces apoptosis in HCT116 colon cancer cells.
Author: Du, Peng|Saidu, Nathaniel Edward Bennett|Intemann, Johanna|Jacob, Claus|Montenarh, Mathias
PMID: 24530428
Journal: Cancer Biol Ther. 2014;15(12):1646-57.
Title: Regulation of dimethyl-fumarate toxicity by proteasome inhibitors.
Author: Booth, Laurence|Cruickshanks, Nichola|Tavallai, Seyedmehrad|Roberts, Jane L|Peery, Matthew|Poklepovic, Andrew|Dent, Paul
PMID: 25482938
Journal: J Biol Chem. 2014 Aug 1;289(31):21544-61.
Title: Role of activating transcription factor 3 (ATF3) in endoplasmic reticulum (ER) stress-induced sensitization of p53-deficient human colon cancer cells to tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis through up-re
Author: Edagawa, Makoto|Kawauchi, Junya|Hirata, Manabu|Goshima, Hiroto|Inoue, Makoto|Okamoto, Tatsuro|Murakami, Akira|Maehara, Yoshihiko|Kitajima, Shigetaka
PMID: 24939851
Journal: Biochem Biophys Res Commun. 2014 Mar 7;445(2):320-6.
Title: Role of ATF3 in synergistic cancer cell killing by a combination of HDAC inhibitors and agonistic anti-DR5 antibody through ER stress in human colon cancer cells.
Author: Liu, Jia|Edagawa, Makoto|Goshima, Hiroto|Inoue, Makoto|Yagita, Hideo|Liu, Zhonghui|Kitajima, Shigetaka
PMID: 24530917
Journal: Mol Pharmacol. 2014 Mar;85(3):451-9.
Title: Triapine and a more potent dimethyl derivative induce endoplasmic reticulum stress in cancer cells.
Author: Trondl, Robert|Flocke, Lea S|Kowol, Christian R|Heffeter, Petra|Jungwirth, Ute|Mair, Georg E|Steinborn, Ralf|Enyedy, Eva A|Jakupec, Michael A|Berger, Walter|Keppler, Bernhard K
PMID: 24378333
Journal: Clin Exp Metastasis. 2015 Oct;32(7):677-87.
Title: Suppression of lung metastases by the CD26/DPP4 inhibitor Vildagliptin in mice.
Author: Jang, Jae-Hwi|Baerts, Lesley|Waumans, Yannick|De Meester, Ingrid|Yamada, Yoshito|Limani, Perparim|Gil-Bazo, Ignacio|Weder, Walter|Jungraithmayr, Wolfgang
PMID: 26233333
Journal: J Cell Biochem. 2016 May;117(5):1078-91.
Title: TRAIL-Induced Caspase Activation Is a Prerequisite for Activation of the Endoplasmic Reticulum Stress-Induced Signal Transduction Pathways.
Author: Lee, Dae-Hee|Sung, Ki Sa|Guo, Zong Sheng|Kwon, William Taehyung|Bartlett, David L|Oh, Sang Cheul|Kwon, Yong Tae|Lee, Yong J
PMID: 26212606
Journal: Nat Commun. 2016 Jun 20;7:11971.
Title: Oncogenic PIK3CA mutations reprogram glutamine metabolism in colorectal cancer.
Author: Hao, Yujun|Samuels, Yardena|Li, Qingling|Krokowski, Dawid|Guan, Bo-Jhih|Wang, Chao|Jin, Zhicheng|Dong, Bohan|Cao, Bo|Feng, Xiujing|Xiang, Min|Xu, Claire|Fink, Stephen|Meropol, Neal J|Xu, Yan|Conlon, Ronald A|Markowitz, Sanford|Kinzler, Kenneth W|Velculesc
PMID: 27321283
Journal: World J Gastroenterol. 2016 Jul 21;22(27):6235-45.
Title: Glucose deprivation induces chemoresistance in colorectal cancer cells by increasing ATF4 expression.
Author: Hu, Ya-Ling|Yin, Yuan|Liu, He-Yong|Feng, Yu-Yang|Bian, Ze-Hua|Zhou, Le-Yuan|Zhang, Ji-Wei|Fei, Bo-Jian|Wang, Yu-Gang|Huang, Zhao-Hui
PMID: 27468213
Journal: J Tradit Chin Med. 2016 Aug;36(4):514-21.
Title: Diterpenoid Tanshinones, the extract from Danshen (Radix Salviae Miltiorrhizae) induced apoptosis in nine human cancer cell lines.
Author: Shen, Li|Lou, Zhaohuan|Zhang, Guangshun|Xu, Guanhua|Zhang, Guangji
PMID: 28459519
Journal: Oncotarget. 2017 Feb 7;8(6):9280-9292.
Title: Co-targeting translation and proteasome rapidly kills colon cancer cells with mutant RAS/RAF via ER stress.
Author: Li, Xiangyun|Li, Mei|Ruan, Hang|Qiu, Wei|Xu, Xiang|Zhang, Lin|Yu, Jian
PMID: 28030835
Journal: Cell Death Dis. 2017 Mar 16;8(3):e2681.
Title: Smad7 knockdown activates protein kinase RNA-associated eIF2alpha pathway leading to colon cancer cell death.
Author: De Simone, Veronica|Bevivino, Gerolamo|Sedda, Silvia|Izzo, Roberta|Laudisi, Federica|Dinallo, Vincenzo|Franze, Eleonora|Colantoni, Alfredo|Ortenzi, Angela|Salvatori, Silvia|Rossi, Piero|Sica, Giuseppe S|Fantini, Massimo C|Stolfi, Carmine|Monteleone, Giova
PMID: 28300830
Journal: Anticancer Res. 2017 Jun;37(6):2975-2984.
Title: Enhanced Susceptibility to 5-Fluorouracil in Human Colon Cancer Cells by Silencing of GRP78.
Author: Yun, Seungpil|Han, Yong-Seok|Lee, Jun Hee|Kim, Sangmin|Lee, Sang Hun
PMID: 28551635
Journal: PLoS One. 2018 Feb 8;13(2):e0191107.
Title: Implication of KRT16, FAM129A and HKDC1 genes as ATF4 regulated components of the integrated stress response.
Author: Evstafieva, Alexandra G|Kovaleva, Irina E|Shoshinova, Maria S|Budanov, Andrei V|Chumakov, Peter M
PMID: 29420561
Journal: Sci Rep. 2018 Feb 16;8(1):3178.
Title: beta-catenin-independent regulation of Wnt target genes by RoR2 and ATF2/ATF4 in colon cancer cells.
Author: Voloshanenko, Oksana|Schwartz, Uwe|Kranz, Dominique|Rauscher, Benedikt|Linnebacher, Michael|Augustin, Iris|Boutros, Michael
PMID: 29453334