Primary Site >> Colorectal Cancer
Gene >> ARHGEF4
| 1. | |||||||||||
| Journal: | Science. 2000 Aug 18;289(5482):1194-7. | ||||||||||
| Title: | Asef, a link between the tumor suppressor APC and G-protein signaling. | ||||||||||
| Author: | Kawasaki, Y|Senda, T|Ishidate, T|Koyama, R|Morishita, T|Iwayama, Y|Higuchi, O|Akiyama, T | ||||||||||
| PMID: | 10947987 | ||||||||||
| 2. | |||||||||||
| Journal: | Mol Cell Biol. 2007 Feb;27(4):1380-93. Epub 2006 Dec 4. | ||||||||||
| Title: | Asef2 functions as a Cdc42 exchange factor and is stimulated by the release of an autoinhibitory module from a concealed C-terminal activation element. | ||||||||||
| Author: | Hamann, Michael J|Lubking, Casey M|Luchini, Doris N|Billadeau, Daniel D | ||||||||||
| PMID: | 17145773 | ||||||||||
| 3. | |||||||||||
| Journal: | J Biol Chem. 2007 Feb 16;282(7):4238-42. Epub 2006 Dec 26. | ||||||||||
| Title: | Crystal structure of the rac activator, Asef, reveals its autoinhibitory mechanism. | ||||||||||
| Author: | Murayama, Kazutaka|Shirouzu, Mikako|Kawasaki, Yoshihiro|Kato-Murayama, Miyuki|Hanawa-Suetsugu, Kyoko|Sakamoto, Ayako|Katsura, Yasuhiro|Suenaga, Atsushi|Toyama, Mitsutoshi|Terada, Takaho|Taiji, Makoto|Akiyama, Tetsu|Yokoyama, Shigeyuki | ||||||||||
| PMID: | 17190834 | ||||||||||
| 4. | |||||||||||
| Journal: | Cell Signal. 2007 Sep;19(9):1973-85. Epub 2007 Jun 2. | ||||||||||
| Title: | Htid-1, the human homolog of the Drosophila melanogaster l(2)tid tumor suppressor, defines a novel physiological role of APC. | ||||||||||
| Author: | Kurzik-Dumke, Ursula|Czaja, Joachim | ||||||||||
| PMID: | 17588722 | ||||||||||
| 5. | |||||||||||
| Journal: | Oncogene. 2007 Dec 6;26(55):7620-267. Epub 2007 Jun 18. | ||||||||||
| Title: | Identification and characterization of Asef2, a guanine-nucleotide exchange factor specific for Rac1 and Cdc42. | ||||||||||
| Author: | Kawasaki, Y|Sagara, M|Shibata, Y|Shirouzu, M|Yokoyama, S|Akiyama, T | ||||||||||
| PMID: | 17599059 | ||||||||||
| 6. | |||||||||||
| Journal: | Nat Struct Mol Biol. 2007 Sep;14(9):814-23. Epub 2007 Aug 19. | ||||||||||
| Title: | Release of autoinhibition of ASEF by APC leads to CDC42 activation and tumor suppression. | ||||||||||
| Author: | Mitin, Natalia|Betts, Laurie|Yohe, Marielle E|Der, Channing J|Sondek, John|Rossman, Kent L | ||||||||||
| PMID: | 17704816 | ||||||||||
| 7. | |||||||||||
| Journal: | Oncogene. 2009 Mar 12;28(10):1357-65. | ||||||||||
| Title: | Asef2 and Neurabin2 cooperatively regulate actin cytoskeletal organization and are involved in HGF-induced cell migration. | ||||||||||
| Author: | Sagara, M|Kawasaki, Y|Iemura, S-i|Natsume, T|Takai, Y|Akiyama, T | ||||||||||
| PMID: | 19151759 | ||||||||||
| 8. | |||||||||||
| Journal: | J Biol Chem. 2009 Aug 14;284(33):22436-43. | ||||||||||
| Title: | Adenomatous polyposis coli and Asef function downstream of hepatocyte growth factor and phosphatidylinositol 3-kinase. | ||||||||||
| Author: | Kawasaki, Yoshihiro|Tsuji, Shinnosuke|Sagara, Masaki|Echizen, Kanae|Shibata, Yoko|Akiyama, Tetsu | ||||||||||
| PMID: | 19525225 | ||||||||||
| 9. | |||||||||||
| Journal: | Hepatobiliary Pancreat Dis Int. 2010 Apr;9(2):149-53. | ||||||||||
| Title: | Proteomic analysis of differentially expressed proteins involving in liver metastasis of human colorectal carcinoma. | ||||||||||
| Author: | Li, Shi-Yong|An, Ping|Cai, Hui-Yun|Bai, Xue|Zhang, Ying-Nan|Yu, Bo|Zuo, Fu-Yi|Chen, Gang | ||||||||||
| PMID: | 20382585 | ||||||||||
| 10. | |||||||||||
| Journal: | J Biol Chem. 2010 Jan 8;285(2):1199-207. | ||||||||||
| Title: | The adenomatous polyposis coli-associated guanine nucleotide exchange factor Asef is involved in angiogenesis. | ||||||||||
| Author: | Kawasaki, Yoshihiro|Jigami, Takafumi|Furukawa, Shiori|Sagara, Masaki|Echizen, Kanae|Shibata, Yoko|Sato, Rina|Akiyama, Tetsu | ||||||||||
| PMID: | 19897489 | ||||||||||
| 11. | |||||||||||
| Journal: | Cell Res. 2012 Feb;22(2):372-86. | ||||||||||
| Title: | Structural basis for the recognition of Asef by adenomatous polyposis coli. | ||||||||||
| Author: | Zhang, Zhenyi|Chen, Leyi|Gao, Lei|Lin, Kui|Zhu, Liang|Lu, Yang|Shi, Xiaoshan|Gao, Yuan|Zhou, Jing|Xu, Ping|Zhang, Jian|Wu, Geng | ||||||||||
| PMID: | 21788986 | ||||||||||
| 12. | |||||||||||
| Journal: | Cancer Sci. 2013 Aug;104(8):1135-8. | ||||||||||
| Title: | Differences in the localization of the adenomatous polyposis coli-Asef/Asef2 complex between adenomatous polyposis coli wild-type and mutant cells. | ||||||||||
| Author: | Kawasaki, Yoshihiro|Furukawa, Shiori|Sato, Rina|Akiyama, Tetsu | ||||||||||
| PMID: | 23910005 | ||||||||||
| 13. | |||||||||||
| Journal: | PLoS One. 2013 Nov 11;8(11):e80609. | ||||||||||
| Title: | The miR-1-NOTCH3-Asef pathway is important for colorectal tumor cell migration. | ||||||||||
| Author: | Furukawa, Shiori|Kawasaki, Yoshihiro|Miyamoto, Masaya|Hiyoshi, Masaya|Kitayama, Joji|Akiyama, Tetsu | ||||||||||
| PMID: | 24244701 | ||||||||||
| 14. | |||||||||||
| Journal: | Cancer Res. 2014 Oct 1;74(19):5480-92. | ||||||||||
| Title: | CDC42 inhibition suppresses progression of incipient intestinal tumors. | ||||||||||
| Author: | Sakamori, Ryotaro|Yu, Shiyan|Zhang, Xiao|Hoffman, Andrew|Sun, Jiaxin|Das, Soumyashree|Vedula, Pavan|Li, Guangxun|Fu, Jiang|Walker, Francesca|Yang, Chung S|Yi, Zheng|Hsu, Wei|Yu, Da-Hai|Shen, Lanlan|Rodriguez, Alexis J|Taketo, Makoto M|Bonder, Edward M|Ver | ||||||||||
| PMID: | 25113996 | ||||||||||
| 15. | |||||||||||
| Journal: | PLoS One. 2016 Apr 25;11(4):e0153125. | ||||||||||
| Title: | Aberrant DNA Methylation: Implications in Racial Health Disparity. | ||||||||||
| Author: | Wang, Xuefeng|Ji, Ping|Zhang, Yuanhao|LaComb, Joseph F|Tian, Xinyu|Li, Ellen|Williams, Jennie L | ||||||||||
| PMID: | 27111221 | ||||||||||
| 16. | |||||||||||
| Journal: | Nat Chem Biol. 2017 Sep;13(9):994-1001. | ||||||||||
| Title: | Peptidomimetic inhibitors of APC-Asef interaction block colorectal cancer migration. | ||||||||||
| Author: | Jiang, Haiming|Deng, Rong|Yang, Xiuyan|Shang, Jialin|Lu, Shaoyong|Zhao, Yanlong|Song, Kun|Liu, Xinyi|Zhang, Qiufen|Chen, Yu|Chinn, Y Eugene|Wu, Geng|Li, Jian|Chen, Guoqiang|Yu, Jianxiu|Zhang, Jian | ||||||||||
| PMID: | 28759015 | ||||||||||
| 17. | |||||||||||
| Journal: | Mol Cell Biol. 2018 Aug 15;38(17). pii: MCB.00135-18. | ||||||||||
| Title: | Truncated Adenomatous Polyposis Coli Mutation Induces Asef-Activated Golgi Fragmentation. | ||||||||||
| Author: | Kim, Sang Bum|Zhang, Lu|Yoon, Jimok|Lee, Jeon|Min, Jaewon|Li, Wenlin|Grishin, Nick V|Moon, Young-Ah|Wright, Woodring E|Shay, Jerry W | ||||||||||
| PMID: | 29866653 | ||||||||||
| 18. | |||||||||||
| Journal: | J Med Chem. 2018 Sep 13;61(17):8017-8028. | ||||||||||
| Title: | Rational Design and Structure Validation of a Novel Peptide Inhibitor of the Adenomatous-Polyposis-Coli (APC)-Rho-Guanine-Nucleotide-Exchange-Factor-4 (Asef) Interaction. | ||||||||||
| Author: | Yang, Xiuyan|Zhong, Jie|Zhang, Qiufen|Qian, Jinxing|Song, Kun|Ruan, Cong|Xu, Jianrong|Ding, Ke|Zhang, Jian | ||||||||||
| PMID: | 30095910 | ||||||||||