Literatures

Primary Site >> Colorectal Cancer

Gene >> APEX1

1.
Journal:	Mol Cell Biol. 1994 Sep;14(9):5997-6003.
Title:	Activation of AP-1 and of a nuclear redox factor, Ref-1, in the response of HT29 colon cancer cells to hypoxia.
Author:	Yao, K S\|Xanthoudakis, S\|Curran, T\|O'Dwyer, P J
PMID:	8065332

2.
Journal:	Cancer Res. 1997 May 1;57(9):1794-7.
Title:	Human apurinic endonuclease 1 expression in a colorectal adenoma-carcinoma sequence.
Author:	Kakolyris, S\|Kaklamanis, L\|Engels, K\|Turley, H\|Hickson, I D\|Gatter, K C\|Harris, A L
PMID:	9135024

3.
Journal:	Z Arztl Fortbild Qualitatssich. 1997 Mar;91(2):125-33.
Title:	[Molecular etiology of colorectal carcinogenesis, clinical manifestations and therapy].
Author:	Jacobasch, G\|Jacobasch, K H
PMID:	9244653

4.
Journal:	J Clin Invest. 2003 Dec;112(12):1887-94.
Title:	The adaptive imbalance in base excision-repair enzymes generates microsatellite instability in chronic inflammation.
Author:	Hofseth, Lorne J\|Khan, Mohammed A\|Ambrose, Mark\|Nikolayeva, Olga\|Xu-Welliver, Meng\|Kartalou, Maria\|Hussain, S Perwez\|Roth, Richard B\|Zhou, Xiaoling\|Mechanic, Leah E\|Zurer, Irit\|Rotter, Varda\|Samson, Leona D\|Harris, Curtis C
PMID:	14679184

5.
Journal:	Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2004 Feb;21(1):64-7.
Title:	[Study on significance of single nucleotide polymorphisms in the redox domain of aprimidinic/apurinic endonuclease/redox factor-1 gene in Chinese sporadic colorectal cancer].
Author:	Tang, Xian-bin\|Hou, Jun\|Tan, Yun-shan\|Zhou, Heng-hua\|Liu, Jia
PMID:	14767913

6.
Journal:	ANZ J Surg. 2004 Apr;74(4):248-59.
Title:	Sexual function after rectal excision.
Author:	Keating, John P
PMID:	15043737

7.
Journal:	DNA Repair (Amst). 2005 Mar 2;4(3):315-25.
Title:	Insight into the functional consequences of hMYH variants associated with colorectal cancer: distinct differences in the adenine glycosylase activity and the response to AP endonucleases of Y150C and G365D murine MYH.
Author:	Pope, Mary Ann\|Chmiel, Nikolas H\|David, Sheila S
PMID:	15661655

8.
Journal:	Mol Pharmacol. 2006 May;69(5):1607-14.
Title:	Apurinic/apyrimidinic endonuclease-1 protein level is associated with the cytotoxicity of L-configuration deoxycytidine analogs (troxacitabine and beta-L-2',3'-dideoxy-2',3'-didehydro-5-fluorocytidine) but not D-configuration deoxycytidine analogs (gemcit
Author:	Lam, Wing\|Park, Shin-Young\|Leung, Chung-Hang\|Cheng, Yung-Chi
PMID:	16481390

9.
Journal:	Cancer Res. 2007 Feb 1;67(3):1395-404.
Title:	Genetic variation in base excision repair genes and the prevalence of advanced colorectal adenoma.
Author:	Berndt, Sonja I\|Huang, Wen-Yi\|Fallin, M Daniele\|Helzlsouer, Kathy J\|Platz, Elizabeth A\|Weissfeld, Joel L\|Church, Timothy R\|Welch, Robert\|Chanock, Stephen J\|Hayes, Richard B
PMID:	17283177

10.
Journal:	Oncogene. 2007 Nov 29;26(54):7517-25. Epub 2007 Jun 18.
Title:	Base excision DNA repair defect in Gadd45a-deficient cells.
Author:	Jung, H J\|Kim, E H\|Mun, J-Y\|Park, S\|Smith, M L\|Han, S S\|Seo, Y R
PMID:	17599061

11.
Journal:	Genet Med. 2007 Dec;9(12):836-41.
Title:	Heterogeneous molecular mechanisms underlie attenuated familial adenomatous polyposis.
Author:	Cattaneo, Francesca\|Molatore, Sara\|Mihalatos, Markos\|Apessos, Angela\|Venesio, Tiziana\|Bione, Silvia\|Grignani, Pierangela\|Nasioulas, Georgios\|Ranzani, Guglielmina Nadia
PMID:	18091433

12.
Journal:	J Exp Clin Cancer Res. 2008 Sep 30;27:49.
Title:	Association of MUTYH Gln324His and APEX1 Asp148Glu with colorectal cancer and smoking in a Japanese population.
Author:	Kasahara, Mayumi\|Osawa, Kayo\|Yoshida, Kana\|Miyaishi, Aiko\|Osawa, Yasunori\|Inoue, Natsuko\|Tsutou, Akimitsu\|Tabuchi, Yoshiki\|Tanaka, Kenichi\|Yamamoto, Masahiro\|Shimada, Etsuji\|Takahashi, Juro
PMID:	18823566

13.
Journal:	Cancer Gene Ther. 2008 Oct;15(10):625-35.
Title:	Chimeric adenoviral vector Ad5/F35-mediated APE1 siRNA enhances sensitivity of human colorectal cancer cells to radiotherapy in vitro and in vivo.
Author:	Xiang, D-B\|Chen, Z-T\|Wang, D\|Li, M-X\|Xie, J-Y\|Zhang, Y-S\|Qing, Y\|Li, Z-P\|Xie, J
PMID:	18535621

14.
Journal:	Nucleic Acids Res. 2008 Mar;36(5):1555-66.
Title:	Regulation of the human AP-endonuclease (APE1/Ref-1) expression by the tumor suppressor p53 in response to DNA damage.
Author:	Zaky, Amira\|Busso, Carlos\|Izumi, Tadahide\|Chattopadhyay, Ranajoy\|Bassiouny, Ahmad\|Mitra, Sankar\|Bhakat, Kishor K
PMID:	18208837

15.
Journal:	Mutat Res. 2008 Feb 1;638(1-2):146-53. Epub 2007 Oct 2.
Title:	DNA repair genetic polymorphisms and risk of colorectal cancer in the Czech Republic.
Author:	Pardini, B\|Naccarati, A\|Novotny, J\|Smerhovsky, Z\|Vodickova, L\|Polakova, V\|Hanova, M\|Slyskova, J\|Tulupova, E\|Kumar, R\|Bortlik, M\|Barale, R\|Hemminki, K\|Vodicka, P
PMID:	17991492

16.
Journal:	Hum Pathol. 2008 Feb;39(2):201-8.
Title:	Increased expression of thioredoxin-1, vascular endothelial growth factor, and redox factor-1 is associated with poor prognosis in patients with liver metastasis from colorectal cancer.
Author:	Noike, Terumasa\|Miwa, Shiro\|Soeda, Junpei\|Kobayashi, Akira\|Miyagawa, Shin-ichi
PMID:	17949784

17.
Journal:	Mutat Res. 2009 Mar 31;674(1-2):131-6.
Title:	Accumulation of oxidatively induced clustered DNA lesions in human tumor tissues.
Author:	Nowsheen, Somaira\|Wukovich, Rebecca L\|Aziz, Khaled\|Kalogerinis, Peter T\|Richardson, Christopher C\|Panayiotidis, Mihalis I\|Bonner, William M\|Sedelnikova, Olga A\|Georgakilas, Alexandros G
PMID:	18948225

18.
Journal:	Mutagenesis. 2009 Nov;24(6):507-12.
Title:	The DNA repair gene APE1 T1349G polymorphism and cancer risk: a meta-analysis of 27 case-control studies.
Author:	Gu, Dongying\|Wang, Meilin\|Wang, Miaomiao\|Zhang, Zhengdong\|Chen, Jinfei
PMID:	19762350

19.
Journal:	Mol Cancer Res. 2009 Dec;7(12):1973-83.
Title:	A novel inhibitor of DNA polymerase beta enhances the ability of temozolomide to impair the growth of colon cancer cells.
Author:	Jaiswal, Aruna S\|Banerjee, Sanjeev\|Panda, Harekrushna\|Bulkin, Charles D\|Izumi, Tadahide\|Sarkar, Fazlul H\|Ostrov, David A\|Narayan, Satya
PMID:	19996303

20.
Journal:	Mutagenesis. 2010 Sep;25(5):463-71.
Title:	Oxidative stress and 8-oxoguanine repair are enhanced in colon adenoma and carcinoma patients.
Author:	Obtulowicz, Tomasz\|Swoboda, Maja\|Speina, Elzbieta\|Gackowski, Daniel\|Rozalski, Rafal\|Siomek, Agnieszka\|Janik, Justyna\|Janowska, Beata\|Ciesla, Jaroslaw M\|Jawien, Arkadiusz\|Banaszkiewicz, Zbigniew\|Guz, Jolanta\|Dziaman, Tomasz\|Szpila, Anna\|Olinski, Ryszard\|Tu
PMID:	20534734

21.
Journal:	Free Radic Biol Med. 2010 Sep 15;49(6):1064-71.
Title:	Aberrant repair of etheno-DNA adducts in leukocytes and colon tissue of colon cancer patients.
Author:	Obtulowicz, Tomasz\|Winczura, Alicja\|Speina, Elzbieta\|Swoboda, Maja\|Janik, Justyna\|Janowska, Beata\|Ciesla, Jaroslaw M\|Kowalczyk, Pawel\|Jawien, Arkadiusz\|Gackowski, Daniel\|Banaszkiewicz, Zbigniew\|Krasnodebski, Ireneusz\|Chaber, Andrzej\|Olinski, Ryszard\|Nair,
PMID:	20600828

22.
Journal:	J Appl Genet. 2010;51(3):343-52.
Title:	Association between single-nucleotide polymorphisms of selected genes involved in the response to DNA damage and risk of colon, head and neck, and breast cancers in a Polish population.
Author:	Jelonek, K\|Gdowicz-Klosok, A\|Pietrowska, M\|Borkowska, M\|Korfanty, J\|Rzeszowska-Wolny, J\|Widlak, P
PMID:	20720310

23.
Journal:	Cancer Epidemiol Biomarkers Prev. 2010 Dec;19(12):3167-73.
Title:	Polymorphisms in base excision repair genes as colorectal cancer risk factors and modifiers of the effect of diets high in red meat.
Author:	Brevik, Asgeir\|Joshi, Amit D\|Corral, Roman\|Onland-Moret, N Charlotte\|Siegmund, Kimberly D\|Le Marchand, Loic\|Baron, John A\|Martinez, Maria Elena\|Haile, Robert W\|Ahnen, Dennis J\|Sandler, Robert S\|Lance, Peter\|Stern, Mariana C
PMID:	21037106

24.
Journal:	J Biol Chem. 2011 Feb 18;286(7):4968-77.
Title:	Distinct roles of Ape1 protein in the repair of DNA damage induced by ionizing radiation or bleomycin.
Author:	Fung, Hua\|Demple, Bruce
PMID:	21081487

25.
Journal:	PLoS One. 2011 Feb 2;6(2):e16691.
Title:	DNA polymerase beta as a novel target for chemotherapeutic intervention of colorectal cancer.
Author:	Jaiswal, Aruna S\|Banerjee, Sanjeev\|Aneja, Ritu\|Sarkar, Fazlul H\|Ostrov, David A\|Narayan, Satya
PMID:	21311763

26.
Journal:	Curr Med Res Opin. 2011 Jul;27(7):1295-302.
Title:	Association of APE1 and hOGG1 polymorphisms with colorectal cancer risk in a Turkish population.
Author:	Canbay, Emel\|Cakmakoglu, Bedia\|Zeybek, Umit\|Sozen, Seyma\|Cacina, Canan\|Gulluoglu, Mine\|Balik, Emre\|Bulut, Turker\|Yamaner, Sumer\|Bugra, Dursun
PMID:	21561390

27.
Journal:	PLoS One. 2011;6(12):e28862.
Title:	Checkpoint signaling, base excision repair, and PARP promote survival of colon cancer cells treated with 5-fluorodeoxyuridine but not 5-fluorouracil.
Author:	Geng, Liyi\|Huehls, Amelia M\|Wagner, Jill M\|Huntoon, Catherine J\|Karnitz, Larry M
PMID:	22194930

28.
Journal:	Int J Radiat Oncol Biol Phys. 2012 Jan 1;82(1):130-7.
Title:	Prognostic significance of human apurinic/apyrimidinic endonuclease (APE/Ref-1) expression in rectal cancer treated with preoperative radiochemotherapy.
Author:	Kim, Jun-Sang\|Kim, Jin-Man\|Liang, Zhe Long\|Jang, Ji Young\|Kim, Sup\|Huh, Gil Ja\|Kim, Ki-Hwan\|Cho, Moon-June
PMID:	21075552

29.
Journal:	Clin Cancer Res. 2012 Nov 1;18(21):5878-87.
Title:	Functional, genetic, and epigenetic aspects of base and nucleotide excision repair in colorectal carcinomas.
Author:	Slyskova, Jana\|Korenkova, Vlasta\|Collins, Andrew R\|Prochazka, Pavel\|Vodickova, Ludmila\|Svec, Jiri\|Lipska, Ludmila\|Levy, Miroslav\|Schneiderova, Michaela\|Liska, Vaclav\|Holubec, Lubos\|Kumar, Rajiv\|Soucek, Pavel\|Naccarati, Alessio\|Vodicka, Pavel
PMID:	22966016

30.
Journal:	Med Oncol. 2013 Jun;30(2):505.
Title:	Polymorphisms in genes of APE1, PARP1, and XRCC1: risk and prognosis of colorectal cancer in a northeast Chinese population.
Author:	Li, Ye\|Li, Shuying\|Wu, Zhiwei\|Hu, Fulan\|Zhu, Lin\|Zhao, Xiaojuan\|Cui, Binbin\|Dong, Xinshu\|Tian, Suli\|Wang, Fan\|Zhao, Yashuang
PMID:	23430444

31.
Journal:	Mutat Res. 2013 Jul 4;755(1):42-8.
Title:	The influence of XPD, APE1, XRCC1, and NBS1 polymorphic variants on DNA repair in cells exposed to X-rays.
Author:	Gdowicz-Klosok, Agnieszka\|Widel, Maria\|Rzeszowska-Wolny, Joanna
PMID:	23669291

32.
Journal:	J Clin Invest. 2013 Jul 1. pii: 65521.
Title:	Colon cancer progression is driven by APEX1-mediated upregulation of Jagged.
Author:	Kim, Mi-Hwa\|Kim, Hong-Beum\|Yoon, Sang Pil\|Lim, Sung-Chul\|Cha, Man Jin\|Jeon, Young Jin\|Park, Sang Gon\|Chang, In-Youb\|You, Ho Jin
PMID:	23863623

33.
Journal:	Redox Rep. 2013;18(5):165-73.
Title:	Apurinic/apyrimidinic endonuclease 1, the sensitive marker for DNA deterioration in dextran sulfate sodium-induced acute colitis.
Author:	Chang, In-Youb\|Kim, Jin Nam\|Maeng, Young Hee\|Yoon, Sang Pil
PMID:	23883737

34.
Journal:	Mol Biol Rep. 2013 Oct;40(10):5921-9.
Title:	Evaluation of tumor suppressor gene expressions and aberrant methylation in the colon of cancer-induced rats: a pilot study.
Author:	Polakova Vymetalkova, Veronika\|Vannucci, Luca\|Korenkova, Vlasta\|Prochazka, Pavel\|Slyskova, Jana\|Vodickova, Ludmila\|Rusnakova, Vendula\|Bielik, Ludovit\|Burocziova, Monika\|Rossmann, Pavel\|Vodicka, Pavel
PMID:	24065530

35.
Journal:	Tumour Biol. 2014 Dec;35(12):12775-6.
Title:	Letter regarding Shen et al. entitled "The APE1 Asp148Glu polymorphism and colorectal cancer susceptibility: a meta-analysis".
Author:	Liu, Fei\|Wei, Yong-Gang\|Wang, Wen-Tao\|Li, Bo
PMID:	25384510

36.
Journal:	Zhonghua Wei Chang Wai Ke Za Zhi. 2014 Nov;17(11):1106-10.
Title:	[Extralevator abdominoperineal excision versus traditional abdominoperineal excision in the treatment of low rectal cancer].
Author:	Zhang, Xin\|Shen, Zhanlong\|Xie, Qiwei\|Yin, Mujun\|Yang, Xiaodong\|Jiang, Kewei\|Wang, Youli\|Cao, Jian\|Ye, Yingjiang\|Wang, Shan\|Liang, Bin
PMID:	25421770

37.
Journal:	Drug Des Devel Ther. 2014 Nov 3;8:2147-60.
Title:	Functional analysis of tanshinone IIA that blocks the redox function of human apurinic/apyrimidinic endonuclease 1/redox factor-1.
Author:	Sui, Jiangdong\|Li, Mengxia\|Qian, Chengyuan\|Wang, Shufeng\|Cheng, Yi\|Chen, Benjamin P C\|Wang, Dong
PMID:	25395832

38.
Journal:	Int J Mol Sci. 2014 Sep 29;15(10):17333-43.
Title:	Effect of APE1 T2197G (Asp148Glu) polymorphism on APE1, XRCC1, PARP1 and OGG1 expression in patients with colorectal cancer.
Author:	Santos, Juliana C\|Funck, Alexandre\|Silva-Fernandes, Isabelle J L\|Rabenhorst, Silvia H B\|Martinez, Carlos A R\|Ribeiro, Marcelo L
PMID:	25268610

39.
Journal:	Recent Results Cancer Res. 2014;203:57-67.
Title:	Ultra low resection versus abdomino-perineal excision in low rectal cancer.
Author:	Holm, Torbjorn
PMID:	25103000

40.
Journal:	World J Gastroenterol. 2014 Jul 14;20(26):8700-8.
Title:	APE1 polymorphisms are associated with colorectal cancer susceptibility in Chinese Hans.
Author:	Zhang, Shi-Heng\|Wang, Lin-Ang\|Li, Zheng\|Peng, Yu\|Cun, Yan-Ping\|Dai, Nan\|Cheng, Yi\|Xiao, He\|Xiong, Yan-Li\|Wang, Dong
PMID:	25024628

41.
Journal:	Oncol Lett. 2014 Apr;7(4):1078-1082.
Title:	Aberrant expression of redox protein Ape1 in colon cancer stem cells.
Author:	Lou, Debao\|Zhu, Lina\|Ding, Huawei\|Dai, Hai-Yan\|Zou, Gang-Ming
PMID:	24944672

42.
Journal:	Mol Med Rep. 2014 Jul;10(1):486-90.
Title:	Growth hormone protects colorectal cancer cells from radiation by improving the ability of DNA damage repair.
Author:	Wu, Xiao-Yu\|Chen, Che\|Yao, Xue-Quan\|Cao, Qin-Hong\|Xu, Zhe\|Li, Wei-Su\|Liu, Fu-Kun\|Li, Gang
PMID:	24788673

43.
Journal:	Tumour Biol. 2014 Mar;35(3):2529-35.
Title:	The APE1 Asp148Glu polymorphism and colorectal cancer susceptibility: a meta-analysis.
Author:	Shen, Erdong\|Liu, Chuan\|Wei, Li\|Hu, Jianbing\|Weng, Jie\|Yin, Qinghua\|Wang, Yajie
PMID:	24254302

44.
Journal:	Int J Cancer. 2014 Jan 15;134(2):376-83.
Title:	8-Oxo-7,8-dihydroguanine and uric acid as efficient predictors of survival in colon cancer patients.
Author:	Dziaman, Tomasz\|Banaszkiewicz, Zbigniew\|Roszkowski, Krzysztof\|Gackowski, Daniel\|Wisniewska, Ewa\|Rozalski, Rafal\|Foksinski, Marek\|Siomek, Agnieszka\|Speina, Elzbieta\|Winczura, Alicja\|Marszalek, Andrzej\|Tudek, Barbara\|Olinski, Ryszard
PMID:	23832862

45.
Journal:	Int J Cancer. 2015 Mar 15;136(6):E488-95.
Title:	Multiple mucin depleted foci, high proliferation and low apoptotic response in the onset of colon carcinogenesis of the PIRC rat, mutated in Apc.
Author:	Femia, Angelo Pietro\|Luceri, Cristina\|Soares, Paulo Victoria\|Lodovici, Maura\|Caderni, Giovanna
PMID:	25257656

46.
Journal:	Cell Biochem Biophys. 2015 Mar;71(2):977-82.
Title:	Susceptibility and REF1 gene polymorphism towards colorectal cancer.
Author:	Yang, Shibin\|Lai, Yuanhui\|Xiao, Longbin\|Han, Fanghai\|Wu, Wenhui\|Long, Shuo\|Li, Wenfeng\|He, Yulong
PMID:	25344644

47.
Journal:	Pol Przegl Chir. 2015 Mar;87(3):121-3.
Title:	Impact of APEX Ile64val Gene Polymorphisms of DNA Repair Ber System on Modulation of the Risk of Colorectal Cancer in the Polish Population.
Author:	Kabzinski, Jacek\|Majsterek, Ireneusz\|Mik, Michal\|Dziki, Adam\|Dziki, Lukasz\|Maciejczak, Lucjan
PMID:	26146106

48.
Journal:	World J Gastroenterol. 2016 Mar 28;22(12):3372-80.
Title:	Association between polymorphisms of APE1 and OGG1 and risk of colorectal cancer in Taiwan.
Author:	Lai, Ching-Yu\|Hsieh, Ling-Ling\|Tang, Reiping\|Santella, Regina M\|Chang-Chieh, Chung Rong\|Yeh, Chih-Ching
PMID:	27022219

49.
Journal:	J Cell Biochem. 2017 Jul;118(7):1868-1878.
Title:	Oxidative Stress Promotes Doxorubicin-Induced Pgp and BCRP Expression in Colon Cancer Cells Under Hypoxic Conditions.
Author:	Pinzon-Daza, Martha L\|Cuellar-Saenz, Yenith\|Nualart, Francisco\|Ondo-Mendez, Alejandro\|Del Riesgo, Lilia\|Castillo-Rivera, Fabio\|Garzon, Ruth
PMID:	28106284

50.
Journal:	Mol Cancer Res. 2017 Jul;15(7):831-841.
Title:	Mitochondrial DNA Integrity Is Maintained by APE1 in Carcinogen-Induced Colorectal Cancer.
Author:	Ballista-Hernandez, Joan\|Martinez-Ferrer, Margaly\|Velez, Roman\|Climent, Consuelo\|Sanchez-Vazquez, Maria M\|Torres, Ceidy\|Rodriguez-Munoz, Adlin\|Ayala-Pena, Sylvette\|Torres-Ramos, Carlos A
PMID:	28360037

51.
Journal:	Gastroenterol Res Pract. 2017;2017:3840243.
Title:	Modulation of Colorectal Cancer Risk by Polymorphisms in 51Gln/His, 64Ile/Val, and 148Asp/Glu of APEX Gene; 23Gly/Ala of XPA Gene; and 689Ser/Arg of ERCC4 Gene.
Author:	Dziki, L\|Dziki, A\|Mik, M\|Majsterek, I\|Kabzinski, J
PMID:	28386271

52.
Journal:	Clin Transl Gastroenterol. 2017 Jul 27;8(7):e109.
Title:	The Association of Low-Penetrance Variants in DNA Repair Genes with Colorectal Cancer: A Systematic Review and Meta-Analysis.
Author:	Aggarwal, Nikhil\|Donald, Neil D\|Malik, Salim\|Selvendran, Subothini S\|McPhail, Mark Jw\|Monahan, Kevin J
PMID:	28749454

53.
Journal:	Eur Rev Med Pharmacol Sci. 2018 Mar;22(5):1286-1289.
Title:	Clinical value of combined detection of serum APE1-Aabs and CEACAM-1 in the diagnosis of colorectal cancer.
Author:	Huajun, W\|Ying, F\|Hongxing, Z\|Weifeng, S\|Pingyang, S\|Mingde, H\|Guoguang, L
PMID:	29565485

54.
Journal:	Mol Genet Genomic Med. 2018 Apr 17.
Title:	Polymorphisms of DNA repair genes are associated with colorectal cancer in patients with Lynch syndrome.
Author:	Kamiza, Abram B\|Hsieh, Ling-Ling\|Tang, Reiping\|Chien, Huei-Tzu\|Lai, Chih-Hsiung\|Chiu, Li-Ling\|Lo, Tsai-Ping\|Hung, Kuan-Yi\|You, Jeng-Fu\|Wang, Wen-Chang\|Hsiung, Chao A\|Yeh, Chih-Ching
PMID:	29664240