Primary Site >> Colorectal Cancer

Gene >> APC2

Journal: Curr Biol. 1999 Jan 28;9(2):105-8.
Title: Identification of APC2, a homologue of the adenomatous polyposis coli tumour suppressor.
Author: van Es, J H|Kirkpatrick, C|van de Wetering, M|Molenaar, M|Miles, A|Kuipers, J|Destree, O|Peifer, M|Clevers, H
PMID: 10021369
Journal: Gene. 2001 Apr 4;267(1):101-10.
Title: Interaction of MCC2, a novel homologue of MCC tumor suppressor, with PDZ-domain Protein AIE-75.
Author: Ishikawa, S|Kobayashi, I|Hamada, J|Tada, M|Hirai, A|Furuuchi, K|Takahashi, Y|Ba, Y|Moriuchi, T
PMID: 11311560
Journal: Development. 2002 Apr;129(7):1751-62.
Title: Drosophila Apc1 and Apc2 regulate Wingless transduction throughout development.
Author: Ahmed, Yashi|Nouri, Ali|Wieschaus, Eric
PMID: 11923210
Journal: Dev Biol. 2002 Oct 1;250(1):71-90.
Title: Drosophila APC2 and APC1 have overlapping roles in the larval brain despite their distinct intracellular localizations.
Author: Akong, Kathryn|McCartney, Brooke M|Peifer, Mark
PMID: 12297097
Journal: Dev Biol. 2002 Oct 1;250(1):91-100.
Title: Drosophila APC2 and APC1 play overlapping roles in wingless signaling in the embryo and imaginal discs.
Author: Akong, Kathryn|Grevengoed, Elizabeth E|Price, Meredith H|McCartney, Brooke M|Hayden, Melissa A|DeNofrio, Jan C|Peifer, Mark
PMID: 12297098
Journal: J Gastrointest Surg. 2008 Oct;12(10):1745-53.
Title: Epigenetic regulation of WNT signaling pathway genes in inflammatory bowel disease (IBD) associated neoplasia.
Author: Dhir, Mashaal|Montgomery, Elizabeth A|Glockner, Sabine C|Schuebel, Kornel E|Hooker, Craig M|Herman, James G|Baylin, Stephen B|Gearhart, Susan L|Ahuja, Nita
PMID: 18716850
Journal: Clin Cancer Res. 2009 Feb 15;15(4):1155-61.
Title: Distinct BRAF (V600E) and KRAS mutations in high microsatellite instability sporadic colorectal cancer in African Americans.
Author: Kumar, Krishan|Brim, Hassan|Giardiello, Francis|Smoot, Duane T|Nouraie, Mehdi|Lee, Edward L|Ashktorab, Hassan
PMID: 19190129
Journal: PLoS One. 2009 Sep 11;4(9):e7012.
Title: Distinct high-profile methylated genes in colorectal cancer.
Author: Mokarram, Pooneh|Kumar, Krishan|Brim, Hassan|Naghibalhossaini, Fakhraddin|Saberi-firoozi, Mehdi|Nouraie, Mehdi|Green, Robert|Lee, Ed|Smoot, Duane T|Ashktorab, Hassan
PMID: 19750230
Journal: Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2010 Feb;35(2):140-5.
Title: [Effect of recombinant pEGFP-N3-APC vectors carrying various APC functional domains on the expression of beta-catenin in HT-29 cells].
Author: Lu, Liang|Huo, Jirong|Liu, Jia|Wu, Jie|Wang, Jie
PMID: 20197613
Journal: Pathol Oncol Res. 2011 Dec;17(4):819-25.
Title: High frequency of genes' promoter methylation, but lack of BRAF V600E mutation among Iranian colorectal cancer patients.
Author: Naghibalhossaini, Fakhraddin|Hosseini, Hamideh Mahmoodzadeh|Mokarram, Pooneh|Zamani, Mozhdeh
PMID: 21455633
Journal: PLoS One. 2012;7(2):e31284.
Title: Defining components of the ss-catenin destruction complex and exploring its regulation and mechanisms of action during development.
Author: Roberts, David M|Pronobis, Mira I|Alexandre, Kelly M|Rogers, Gregory C|Poulton, John S|Schneider, Daniel E|Jung, Kuo-Chen|McKay, Daniel J|Peifer, Mark
PMID: 22359584
Journal: Mol Biol Cell. 2012 Jun;23(11):2041-56.
Title: Regulation of Wnt signaling by the tumor suppressor adenomatous polyposis coli does not require the ability to enter the nucleus or a particular cytoplasmic localization.
Author: Roberts, David M|Pronobis, Mira I|Poulton, John S|Kane, Eric G|Peifer, Mark
PMID: 22513088
Journal: Mol Biol Rep. 2013 May;40(5):3851-7.
Title: Different patterns of DNA methylation of the two distinct O6-methylguanine-DNA methyltransferase (O6-MGMT) promoter regions in colorectal cancer.
Author: Mokarram, P|Zamani, M|Kavousipour, S|Naghibalhossaini, F|Irajie, C|Moradi Sarabi, M|Hosseini, S V
PMID: 23271133
Journal: PLoS One. 2013 Jul 1;8(7):e68072.
Title: Functional comparison of human adenomatous polyposis coli (APC) and APC-like in targeting beta-catenin for degradation.
Author: Schneikert, Jean|Vijaya Chandra, Shree Harsha|Ruppert, Jan Gustav|Ray, Suparna|Wenzel, Eva Maria|Behrens, Jurgen
PMID: 23840886
Journal: Genetics. 2014 Aug;197(4):1285-302.
Title: Testing models of the APC tumor suppressor/beta-catenin interaction reshapes our view of the destruction complex in Wnt signaling.
Author: Yamulla, Robert J|Kane, Eric G|Moody, Alexandra E|Politi, Kristin A|Lock, Nicole E|Foley, Andrew V A|Roberts, David M
PMID: 24931405
Journal: Mol Biol Cell. 2015 Dec 1;26(24):4503-18.
Title: The two SAMP repeats and their phosphorylation state in Drosophila Adenomatous polyposis coli-2 play mechanistically distinct roles in negatively regulating Wnt signaling.
Author: Kunttas-Tatli, Ezgi|Von Kleeck, Ryan A|Greaves, Bradford D|Vinson, David|Roberts, David M|McCartney, Brooke M
PMID: 26446838
Journal: J Biol Chem. 2016 Jun 10;291(24):12747-60.
Title: The Poly(ADP-ribose) Polymerase Enzyme Tankyrase Antagonizes Activity of the beta-Catenin Destruction Complex through ADP-ribosylation of Axin and APC2.
Author: Croy, Heather E|Fuller, Caitlyn N|Giannotti, Jemma|Robinson, Paige|Foley, Andrew V A|Yamulla, Robert J|Cosgriff, Sean|Greaves, Bradford D|von Kleeck, Ryan A|An, Hyun Hyung|Powers, Catherine M|Tran, Julie K|Tocker, Aaron M|Jacob, Kimberly D|Davis, Beckley
PMID: 27068743
Journal: Development. 2016 Jul 15;143(14):2629-40.
Title: Proteomic analysis reveals APC-dependent post-translational modifications and identifies a novel regulator of beta-catenin.
Author: Blundon, Malachi A|Schlesinger, Danielle R|Parthasarathy, Amritha|Smith, Samantha L|Kolev, Hannah M|Vinson, David A|Kunttas-Tatli, Ezgi|McCartney, Brooke M|Minden, Jonathan S
PMID: 27287809
Journal: J Biol Chem. 2017 May 5;292(18):7566-7577.
Title: A novel microRNA located in the TrkC gene regulates the Wnt signaling pathway and is differentially expressed in colorectal cancer specimens.
Author: Dokanehiifard, Sadat|Yasari, Atena|Najafi, Hadi|Jafarzadeh, Meisam|Nikkhah, Maryam|Mowla, Seyed Javad|Soltani, Bahram M
PMID: 28100780
Journal: Clin Epidemiol. 2017 Jul 13;9:377-384.
Title: Fecal occult blood versus DNA testing: indirect comparison in a colorectal cancer screening population.
Author: Brenner, Hermann|Chen, Hongda
PMID: 28761377
Journal: J Cell Biochem. 2018 Jul;119(7):5104-5117.
Title: Introduction of hsa-miR-103a and hsa-miR-1827 and hsa-miR-137 as new regulators of Wnt signaling pathway and their relation to colorectal carcinoma.
Author: Fasihi, Ali|M Soltani, Bahram|Atashi, Amir|Nasiri, Shirzad
PMID: 28817181